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Quasiparticle Weight And Effective Mass Of The Landau Liquid From The Complex-Frequency Formalism, Aydin Cem Keser, Oleg P. Sushkov Dec 2025

Quasiparticle Weight And Effective Mass Of The Landau Liquid From The Complex-Frequency Formalism, Aydin Cem Keser, Oleg P. Sushkov

Turkish Journal of Physics

We present a method for calculating the effective mass and quasiparticle weight of a Landau Fermi liquid using time-ordered Green’s functions and a Wick rotation to the imaginary frequency axis. This technique simplifies the evaluation of self-energy derivatives by ensuring analytic properties compatible with contour deformations. We apply the method to the electron gas in both two and three spatial dimensions within the random phase approximation (RPA), and derive explicit expressions for the static and dynamic contributions to the self-energy. Our results confirm known limits at weak coupling and offer an accurate and transparent route to evaluate effective mass and …


Application Of Polarization Transfer Algorithm In Organic Molecules With Three Nonequivalent Coupled Spins, Dim Safin, Alexander Perepukhov, Sergei Rzhevskiy, Yuri Belousov Dec 2025

Application Of Polarization Transfer Algorithm In Organic Molecules With Three Nonequivalent Coupled Spins, Dim Safin, Alexander Perepukhov, Sergei Rzhevskiy, Yuri Belousov

Turkish Journal of Physics

Polarization transfer between three $1/2$ nuclear spins in a specially prepared isotopically enriched molecule diethylphthalimide malonate-2-$^{13}$C,$^{15}$N molecule was obtained using the nuclear magnetic resonance (NMR) method. The polarization transfer was performed by implementing a sequence of radio frequency pulses and waiting intervals. Relaxation times and NMR spectrum for the studied nuclei were measured in samples of molecules with natural and enriched isotopes $^{13}$C and $^{15}$N. Measurements of the proton relaxation rate for diethylphthalimidomalonate and diethylpthalimidomalonate-2-$^{13}$C,$^{15}$N showed an increase in relaxation rate by a factor of 4 for protons bound to $^{13}$C,$^{15}$N nuclei. The use of the quantum polarization transfer method …


First-Principles And Deep Learning Frameworks To Predict The Electronic, Magnetic And Electrical Properties Of V-Doped Sic Nanotube, Debarati Dey Roy, Sevda Rzayeva, Sevinj Guluzade, Vusala Nabi Jafarova Dec 2025

First-Principles And Deep Learning Frameworks To Predict The Electronic, Magnetic And Electrical Properties Of V-Doped Sic Nanotube, Debarati Dey Roy, Sevda Rzayeva, Sevinj Guluzade, Vusala Nabi Jafarova

Turkish Journal of Physics

Nowadays, with the miniaturization of nanoindustry, we are increasingly interested in doping effects for nanotube systems. In this study, based on density functional theory (DFT) and local spin density approximation (LDA) methods within Hubbard U corrections, the electronic, magnetic and electrical properties of single-wall silicon carbide nanotubes doped with vanadium were theoretically studied. Although the undoped SiC system is nonmagnetic, the V-doped SiC nanotube induces magnetism and the total magnetic moment of this magnetic material is equal to ~1 µB. Density of states calculations indicated that the magnetization of SiC:V single-wall nanotubes mainly comes from the 2p orbitals of carbon …


Corrigendum To “Circular Motion And Thermodynamic Characteristics Of Particles Around A Quintessential Nonrotating Black Hole” [Turkish Journal Of Physcis 49 (3) 2025 72-91], Indrajit Halder, Kamal Lochan Mahanta, Rakesh Ranjan Sahoo Dec 2025

Corrigendum To “Circular Motion And Thermodynamic Characteristics Of Particles Around A Quintessential Nonrotating Black Hole” [Turkish Journal Of Physcis 49 (3) 2025 72-91], Indrajit Halder, Kamal Lochan Mahanta, Rakesh Ranjan Sahoo

Turkish Journal of Physics

This corrigendum addresses an error in equation (35) in the original published version of this article. This error led to minor inaccuracies in subsequent equations.To correct this oversight and ensure the accuracy of the scholarly record, the corrected equations are provided below for reference. The authors apologize for any inconvenience caused and state that the scientific conclusions are unaffected. Corrected equations ofsection 3.3. [2,3]:

The original article can be accessed at: https://doi.org/10.55730/1300-0101.2777


Exposures, Protections, And Barriers: Advancing Understanding Of Agricultural Worker Health, Alexandra A. Farfalla Dec 2025

Exposures, Protections, And Barriers: Advancing Understanding Of Agricultural Worker Health, Alexandra A. Farfalla

Theses & Dissertations

Farming is a hazardous occupation. Exposures are multifactorial, variable, and shaped by overlapping tasks, environments, and social contexts. This dissertation aimed to illustrate the complexity of agricultural exposures and the barriers to protective practices through three complementary studies.

The first study examined co-exposures to solvents and noise as risk factors for hearing loss (HL) among 7,495 farmers and ranchers in a 7-state region. Results indicated nearly 60% of co-exposed participants reported hearing loss, with an adjusted odds ratio nearly six-fold (OR=6.03, [4.67-7.78]) for moderate/severe HL. This work highlights the importance of recognizing chemical exposures as a modality in HL in …


Feasibility And Function Of A Tilt-In-Space Wheelchair Insert For Low Resource Settings (Development Of The Open Tilt Base), Luke Mcauley, Karen Menard Dec 2025

Feasibility And Function Of A Tilt-In-Space Wheelchair Insert For Low Resource Settings (Development Of The Open Tilt Base), Luke Mcauley, Karen Menard

Student Capstone Papers

The ability to move and be mobile is a basic part of human function. For those without the muscle control and/or strength to attain and maintain the posture necessary for basic movement and mobility a device is necessary to support them and provide them with the highest level of independence possible. This type of device comes at a significant cost and need for highly customizable products which are difficult to obtain in most situations, but especially in Low-Middle-Income Countries (LMIC). The product discussed in this paper is designed to provide a cost effective solution for those in need of a …


Public Perception About Covid-19 Vaccine Hesitancy In South Central Nebraska, Rita Nnenne Oparaocha Dec 2025

Public Perception About Covid-19 Vaccine Hesitancy In South Central Nebraska, Rita Nnenne Oparaocha

Biology Theses, Dissertations, and Student Creative Activity

The COVID-19 pandemic created a shift in the trajectory of vaccination hesitancy, altering risk perceptions and vaccination attitudes among individuals in rural communities. The 5C framework highlights confidence, complacency, constraints, calculation, and collective responsibility as influencing factors of vaccine hesitancy. This study assessed the proportion of adults who refused COVID-19 vaccination and identified the individual reasons for hesitancy among those who refused the COVID -19 vaccines in South Central Nebraska. Data was analyzed from a local cross-sectional public health survey administered to 2,034 adult participants over a six-month period (March-August 2024), including 91 respondents who were from outside the seven-county …


Comparisons Of Fish Communities Between A Restored And A Control Pool Of The Mississippi River: A Before-And-After Examination, Hannah Lenning Dec 2025

Comparisons Of Fish Communities Between A Restored And A Control Pool Of The Mississippi River: A Before-And-After Examination, Hannah Lenning

Biology Theses, Dissertations, and Student Creative Activity

The quality and availability of valuable backwater habitats have declined in many rivers, including the Upper Mississippi River (UMR), due to river modifications and land use change. Habitat Rehabilitation and Enhancement Projects (HREPs) are implemented by the Upper Mississippi River Restoration Program and often aim to mitigate accelerated sedimentation and degradation of backwater habitats. One HREP in Pool 12 of the UMR targeted overwintering fish habitat by restoring four backwaters within 14 RKM. Fish community data was collected before (2006-2012) and after (2020-2024) restoration in Pool 12 and a downstream, control reach, Pool 13. The first objective of my study …


Self-Assembling Rna Nanostructures Are Highly Sensitive To Environmental Conditions, Jordan Aposhian, Surya Pratap S. Deopa, Scott Horowitz, Joseph D. Yesselman Dec 2025

Self-Assembling Rna Nanostructures Are Highly Sensitive To Environmental Conditions, Jordan Aposhian, Surya Pratap S. Deopa, Scott Horowitz, Joseph D. Yesselman

Chemistry and Biochemistry: Faculty Scholarship

Recent developments in RNA nanotechnology have led to an increase in the design of specific, higher-order RNA structures, which will ultimately be used in drug delivery and immunomodulation applications. As researchers create RNA nanostructures with the intention of making them a standard tool in molecular biologists' toolkits, further investigation is required into the robustness of RNA designs. Primarily, in what different molecular contexts are the designed and intended nanostructures stable? In this work, we show that RNA nanostructure self-assembly is highly sensitive to environmental conditions by using second-order right-angle light scattering. While a test RNA hexagonal grid nanostructure forms correctly …


Mind The Gap: Intergenerational Perspectives On Mental Illness Within Ghanaian American Communities, Ama Danso-Ayesu Dec 2025

Mind The Gap: Intergenerational Perspectives On Mental Illness Within Ghanaian American Communities, Ama Danso-Ayesu

Electronic Theses and Dissertations

This research explores attitudes toward mental illness among Ghanaian immigrants and

first-generation Ghanaian Americans, with particular focus on factors that influence

stigma. Guided by Bronfenbrenner’s Bioecological Model, the study utilized the

Community Attitudes Toward Mental Illness (CAMI) Scale to measure four dimensions

of stigma, including authoritarianism, benevolence, social restrictiveness, and community

mental health ideology. A comparative, cross-sectional design was employed to examine

differences between immigrant and American-born participants. The findings revealed

generational differences where Ghanaian immigrants reported higher levels of

authoritarian and socially restrictive beliefs, while first-generation Ghanaian Americans

demonstrated more benevolent and inclusive attitudes. Interpreted through the ecological

systems …


Examining The Effects Of Video Modeling To Enhance Culturally Specific Social Greeting Skills In Preschoolers With Asd In Saudi Arabia, Sarah Alzahrani Dec 2025

Examining The Effects Of Video Modeling To Enhance Culturally Specific Social Greeting Skills In Preschoolers With Asd In Saudi Arabia, Sarah Alzahrani

Electronic Theses and Dissertations

A lack of social communication skills, including initiation and responding, has been a prominent characteristic of children diagnosed with ASD (Kanner, 1943; Kroeger et al., 2007). Enhancing these skills in children with ASD during early childhood is crucial to their future relationships, friendships, participation in communal activities, and overall lowering the likelihood of adverse long-term effects, giving significance to this age as a pivotal period for enhancing various skills (Hart Barnett, 2018). Failure to provide interventions to address social communication in children with ASD, specifically in cultures that value this skill, can impede their integration into that society. Thus, this …


Effectiveness Of Picture Exchange Communication System On Functional Communication For Saudi Children With Autism Spectrum Disorder (Asd), Mohammed Albahrani Dec 2025

Effectiveness Of Picture Exchange Communication System On Functional Communication For Saudi Children With Autism Spectrum Disorder (Asd), Mohammed Albahrani

Electronic Theses and Dissertations

Autism Spectrum Disorder (ASD) is a complex neurodevelopmental disorder characterized by restricted interests, repetitive or inflexible behaviors, and challenges with communication and socialization (Flannery & Wisner-Carlson, 2020). Children with expressive communication disorders, including those with ASD, can benefit from using Augmentative and Alternative Communication (AAC) as a tool to improve their communication skills (Chazin et al., 2016). The AAC approach helps them learn and communicate more effectively by addressing various needs, such as making requests, commenting, or responding to questions (Mirenda, 2001). Many families, special education classrooms, and inclusive settings have adopted the Picture Exchange Communication System (PECS), an evidence-based …


Counselor Perspectives On Substance Use Treatment In Pennsylvania As Medical Cannabis Laws Evolve, Renee L. Ludwig Dec 2025

Counselor Perspectives On Substance Use Treatment In Pennsylvania As Medical Cannabis Laws Evolve, Renee L. Ludwig

Electronic Theses and Dissertations

Cannabis, once primarily regarded as a recreational or “party” drug, has undergone a significant shift in public and medical perception over the past two decades. It is now increasingly recognized as a therapeutic agent prescribed within clinical settings. While substantial research has examined the general use of medical cannabis, relatively little attention has been given to its implications for substance use counselors treating clients who use medical cannabis during treatment for substance use disorders. The purpose of this study is to explore the perceptions of substance use counselors regarding client use of medical cannabis and to investigate how such use …


A Fish & A Bird, Deanna Moorehead Dec 2025

A Fish & A Bird, Deanna Moorehead

Theses

As a curtain of trees opens and dawn breaks over the glistening waters of Lake Ontario, a fish and a bird spot each other through the surface and fall madly in love. They dance and sing together from their respective atmospheres, yet each time the bird soars past the water's edge and onto the beach, the fish cannot follow. Night after night, by the light of the moon, the fish trains herself to leap out of the water, hoping to breach high enough to join her beau above. Late one afternoon, the fish approaches the shore, where the bird stands …


Assessment Of Polymeric Chloroquine Formulations For Targeted Therapy Of Ulcerative Colitis And Metastatic Colorectal Cancer, Neha Kumari Dec 2025

Assessment Of Polymeric Chloroquine Formulations For Targeted Therapy Of Ulcerative Colitis And Metastatic Colorectal Cancer, Neha Kumari

Theses & Dissertations

Effective targeted drug delivery is a critical unmet need in the management of both ulcerative colitis and metastatic colorectal cancer, where conventional systemic therapies may be hindered by suboptimal efficacy and significant side effects. This thesis explores the development and preclinical assessment of polymeric chloroquine (PCQ)-based nanotherapeutics, leveraging stimuli-responsive designs for disease-specific delivery and action.

For ulcerative colitis, a reactive oxygen species (ROS)-responsive nanogel system was engineered to release PCQ, a macromolecular derivative of hydroxychloroquine, specifically in the inflamed areas within the colon. Nanogels with well-defined size and positive surface charge were synthesized via reversible fragmentation chain transfer (RAFT) polymerization …


Role Of Nadph Oxidase 4 In Murine Cancer-Associated Fibroblast, Faith M. Gomez Dec 2025

Role Of Nadph Oxidase 4 In Murine Cancer-Associated Fibroblast, Faith M. Gomez

Theses & Dissertations

Breast cancer is the second leading cause of cancer deaths in women in the United States. Frontline hormone therapies for breast cancer prove ineffective in triple negative breast cancer tumors wherein the hormones estrogen, progesterone, and HER2 are downregulated or absent; therefore, patients diagnosed with triple negative breast cancer are primarily limited to chemotherapies which carry a higher failure and resistance rate. Here we target cancer associated fibroblasts as potential drivers of chemoresistance in triple negative breast cancer. We investigated the mechanism by which Nox4 regulates the YAP/TAZ pathway in modulating DTX sensitivity and sought to determine if targeting Nox4 …


Regulation Of Chromatin Remodeling By The Post-Hsa Domain Of Brg1, A Subunit The Baf Atp-Dependent Chromatin Remodeling Complex, Min Sze Ewe Dec 2025

Regulation Of Chromatin Remodeling By The Post-Hsa Domain Of Brg1, A Subunit The Baf Atp-Dependent Chromatin Remodeling Complex, Min Sze Ewe

Theses & Dissertations

The ATP-dependent chromatin remodeler BAF complex regulates nucleosome positioning, chromatin accessibility, and tissue specific gene expression. Its catalytic subunit, BRG1, contains several regulatory domains including the post-HSA region, proposed to modulate ATPase activity. Multiple cancer-associated mutations map to these regulatory regions underscoring their importance, yet the precise role of the post-HSA region in chromatin remodeling remains poorly understood.

To investigate the function of the post-HSA domain, we ectopically expressed FLAG-tagged BRG1 with post-HSA deletion (Δpost-HSA BRG1) in mouse embryonic stem cells. Western blot analysis confirmed expression of the mutant protein. To determine the effects of mutant protein expression on chromatin …


Macroinvertebrate Community Dynamics In A Recovering, Hypersaline Estuary, Catherine M. Eckert, Claudia A. Tamez, Erin E. Easton, David Hicks Dec 2025

Macroinvertebrate Community Dynamics In A Recovering, Hypersaline Estuary, Catherine M. Eckert, Claudia A. Tamez, Erin E. Easton, David Hicks

School of Earth, Environmental, & Marine Sciences Faculty Publications

The Bahia Grande is a 6,500—acre tidal basin located at the southernmost tip of Texas. Tidal flow into this coastal estuary was cut off in the 1930s, causing the basin to dry up for ~70 y. A pilot channel connecting the Bahia Grande to tidal waters was constructed in 2005, allowing flooding of the basin to occur. Throughout the period reported herein (2005–2019), the system remained characterized by persistent spatial and temporal episodes of extreme hypersalinity (>70)—a critical factor influencing estuarine community composition and driving key ecological processes. With additional rehabilitation actions forthcoming, characterization of the estuary is essential …


Perron Theorem Application To A Second-Order Differential Equation With Small Advances, Jason Hendrix Dec 2025

Perron Theorem Application To A Second-Order Differential Equation With Small Advances, Jason Hendrix

Theses and Dissertations

We analyze a delayed second order differential equation with small delay parameters, proving spectral stability via the characteristic quasi-polynomial and establishing uniform bounds on derivatives of the Green’s function to ensure sign preservation under perturbation, providing a foundation for monotone iteration methods. These results aim to advance the functional-analytic framework for traveling wave solutions in delayed reaction-diffusion systems.


‘If You Can Dream It, You Can Do It:’ Bridging Creative Ideas & Beliefs In A Neurodiverse Workforce Through Autonomy & Social Support, Mesaley A. Alemseged Dec 2025

‘If You Can Dream It, You Can Do It:’ Bridging Creative Ideas & Beliefs In A Neurodiverse Workforce Through Autonomy & Social Support, Mesaley A. Alemseged

Industrial-Organizational Psychology Dissertations

Reports from the business world highlight the competitive advantage that neurodiversity can provide for workplace creativity and innovation through the inclusion of workers who represent a broad range of perspectives and abilities. However, while neurodivergent individuals have naturally divergent ways of thinking, producing creative works might not come as easily in workplaces designed for neurotypical forms of thinking and working. Drawing from the componential theory of creativity, this study sought to explore how neurodivergence, as it relates to creativity-relevant processes, and work characteristics related to the social environment can influence creativity across the various stages of the creative process. While …


Accepting Vs Understanding, Transgender Aliens And Alienation, Reyna G. Aliah Dec 2025

Accepting Vs Understanding, Transgender Aliens And Alienation, Reyna G. Aliah

English

Trans people have been the subject of intense discrimination in recent years, suffering dehumanization from right-wing and conservative groups. This dehumanization (and the fear resulting from it) parallels common attitudes in science fiction about actual aliens. Orson Scott Card’s Hierarchy of Foreignness classifies individuals and species into five categories, depending on their sentience; whether they are from the same city, nation, or planet; and whether communication is possible. This paper examines how transgender people can be classified according to this system on a societal level, with said class depending on the lens used to view them as well as the …


Playing By Feel: Gender, Emotion, And Social Norms In Overwatch Role Choice, Cristo Leon, Angela Arroyo, James Lipuma Dec 2025

Playing By Feel: Gender, Emotion, And Social Norms In Overwatch Role Choice, Cristo Leon, Angela Arroyo, James Lipuma

STEM for Success Resources

This paper explores how emotion, gameplay context, and social norms shape role choice in both digital and institutional systems. Using Overwatch as a case study, it examines gendered experiences of physiological excitement and decision-making during play. Women often describe heightened emotional engagement where victory represents both personal achievement and resistance to cultural expectations. Such emotions influence situational choices, including whether to play as a Tank, DPS, or Support, and which hero to select based on perceived risk or visibility. Drawing on feminist game studies and transdisciplinary communication, the authors argue that role preference is determined not only by game mechanics …


Exploring The Medicinal Properties Of Indigenous Plants Within An Enabling Program: Bridging The Gap Between School, Aboriginal And Torres Strait Islander Knowledge And Science, Sharon L. Gough, Julie Sartori, Angela Jones Dec 2025

Exploring The Medicinal Properties Of Indigenous Plants Within An Enabling Program: Bridging The Gap Between School, Aboriginal And Torres Strait Islander Knowledge And Science, Sharon L. Gough, Julie Sartori, Angela Jones

Research outputs 2022 to 2026

In 2021, less than half of Australian universities considered Indigenous perspectives in curriculum development, with only 15% ensuring Indigenous content in all courses. Literature acknowledges that a strengths-based approach to the inclusion of Aboriginal and Torres Strait Islander knowledge and perspectives, enhances representation and decolonises curriculum. In 2020, Noongar elder Vivienne Hansen, and John Horsfall created Noongar Bush Medicine, detailing the medicinal use of Indigenous plants. Yeshi, Turpin, Jamtsho, and Wangchuk noted that many Aboriginal and Torres Strait Islander communities use native plants for health purposes. However, there is limited data on the therapeutic efficacy of these plants. In 2024, …


Leveraging Transcranial Ultrasound Stimulation To Enhance Self-Regulation In Emotion And Sleep, Suraya Dunsford, Mica Komarnyckyj, Elsa Fouragnan Dec 2025

Leveraging Transcranial Ultrasound Stimulation To Enhance Self-Regulation In Emotion And Sleep, Suraya Dunsford, Mica Komarnyckyj, Elsa Fouragnan

School of Psychology

This Perspective article discusses the emerging potential of transcranial ultrasound stimulation (TUS) as a non-invasive neuromodulatory technique for enhancing self-regulatory processes, particularly emotion and sleep regulation, in healthy individuals. Offering high spatial precision and the ability to target both cortical and deep brain regions, TUS uses focused ultrasound waves to induce acute and delayed effects on brain activity. We propose that combining TUS with neurofeedback methods and/or specific cognitive training exercises may capitalise on these neuroplastic effects, thereby augmenting and prolonging their impact to support lasting improvements in self-regulation. We focus on the domains of sleep and emotion regulation, where …


Living Experiences Of Indigenous Health Practice: Belizean Maya Communities And Belize Migrants, Kristina Baines Dec 2025

Living Experiences Of Indigenous Health Practice: Belizean Maya Communities And Belize Migrants, Kristina Baines

Maya America: Journal of Essays, Commentary, and Analysis

Belize Maya communities, like many indigenous communities around the world, have long experienced challenges to maintaining health as they interface with an ever-expanding globalized model of development. This essay explores the relationship between traditional ecological practices and health in the context of a holistic understanding of what makes healthy bodies, healthy communities and healthy lives. Using the author’s Embodied Ecological Heritage (EEH) framework and a phenomenological lens, the essay shares how sensory experiences become embodied through everyday practice, promoting health and general wellbeing. This grounded theory, developed in and with Maya communities, helps us understand ways to consider and support …


Abnormalities In Sensorimotor Brain Function Are Related To Chronicity Of Low Back Pain, Jo Armour Smith, Rongwen Tain, Kelli G. Sharp, Laura M. Glynn, Linda R. Van Dillen, Jesse V. Jacobs, Steven C. Cramer Dec 2025

Abnormalities In Sensorimotor Brain Function Are Related To Chronicity Of Low Back Pain, Jo Armour Smith, Rongwen Tain, Kelli G. Sharp, Laura M. Glynn, Linda R. Van Dillen, Jesse V. Jacobs, Steven C. Cramer

Physical Therapy Faculty Articles and Research

Maladaptive plasticity in the brain may contribute to chronic low back pain (LBP) and underlie the altered postural control of the lumbopelvic musculature that is evident in some individuals with LBP. We recently described an MRI-compatible leg-raise paradigm to measure brain activity associated with lumbopelvic postural control. The objective of this study was to compare brain function in young adults with and without a history of LBP and to determine relationships between brain function, pain, and postural control characteristics. We recruited 55 participants with a history of LBP, who were asymptomatic when studied, and 30 healthy controls. Postural control during …


Evaluation And Calibration Of Coupled Low-Cost Particulate Matter Sensors, Tyler Cargill Dec 2025

Evaluation And Calibration Of Coupled Low-Cost Particulate Matter Sensors, Tyler Cargill

McKelvey School of Engineering Graduate Student Theses & Dissertations

Low-cost sensors (LCS), if used appropriately, are useful instruments to elucidate human exposure to particles suspended in the air (i.e. particulate matter, PM). Characterizing this exposure is crucial, as exposure to PM2.5 (i.e. particles with aerodynamic diameter ≤ 2.5 μm) negatively affects the respiratory, cardiovascular, and other organ systems and is the leading environmental burden for global mortality. Similarly, exposure to particles with aerodynamic diameters greater than 2.5 μm and less than or equal to 10 μm, here forth termed as PMCoarse, is known to cause health ailments for the upper respiratory system. This dissertation focuses on the MODULAIRTM-PM (MOD-PM), …


Investigating Metabolic Heterogeneity In Engineered Isogenic Microorganisms, Xinyue Mu Dec 2025

Investigating Metabolic Heterogeneity In Engineered Isogenic Microorganisms, Xinyue Mu

McKelvey School of Engineering Graduate Student Theses & Dissertations

Engineered microorganisms play an increasingly important role in the sustainable production of fuels, bioplastics, and other valuable biomaterials. Successful industrial deployment depends on maximizing product titers and ensuring process robustness at large scale. However, one of the major obstacles is non-genetic cell-to-cell heterogeneity arising from stochastic intracellular processes. Such heterogeneity can result in subpopulations that divert substrates toward growth rather than product biosynthesis, ultimately reducing yield and contributing to batch-to-batch inconsistency. To better understand the mechanisms by which cell-to-cell variation emerges, propagates, and impacts bioproduction, this dissertation investigated how intracellular energetic dynamics and stochastic biosynthetic noise contributed to metabolic heterogeneity …


Transforming Co2 Into Value-Added Products: Liquefied Petroleum Gas And Solid Carbon Materials, Kaiying Wang Dec 2025

Transforming Co2 Into Value-Added Products: Liquefied Petroleum Gas And Solid Carbon Materials, Kaiying Wang

McKelvey School of Engineering Graduate Student Theses & Dissertations

The escalating climate crisis, driven by anthropogenic carbon dioxide (CO2) emissions, necessitates the development of advanced Carbon Capture and Utilization (CCU) technologies. A critical distinction within CCU lies between transient carbon cycling, which converts CO2 into fuels, and permanent sequestration, which transforms it into durable, solid materials. This dissertation addresses fundamental catalytic challenges across both pathways to develop economically viable and technologically sound solutions for CO2 valorization. This work seeks to answer two primary research questions: (1) How can the catalyst temperature mismatch and stability limitations in the tandem conversion of CO2 to Liquefied Petroleum Gas (LPG) be overcome to …


Beyond Precision: Ambiomic Survivorship In Childhood And Aya Cancer., Juan Antonio Ortega-García, Omar Shakeel, Nicole Wood, Antonio Pérez-Martínez, Jose Luís Fuster-Soler, Mark D. Miller Dec 2025

Beyond Precision: Ambiomic Survivorship In Childhood And Aya Cancer., Juan Antonio Ortega-García, Omar Shakeel, Nicole Wood, Antonio Pérez-Martínez, Jose Luís Fuster-Soler, Mark D. Miller

Manuscripts, Articles, Book Chapters and Other Papers

Background: Survival among children and adolescents and young adults (AYA) with cancer has improved substantially over recent decades; however, dominant survivorship models remain reactive-activated post-treatment and anchored to static exposure- and organ-based screening. This design underuses the anticipatory window at diagnosis and overlooks environmental and social determinants that modulate outcomes across the life course. Methods: We narratively reviewed international frameworks including the Children's Oncology Group (COG), the International Late Effects of Childhood Cancer Guideline Harmonization Group (IGHG), the Pan-European Network for Care of Survivors after Childhood and Adolescent Cancer (PanCare) and the National Comprehensive Cancer Network (NCCN), and synthesized evidence …