Digital Commons Network^™

Serum High Sensitivity Cardiac Troponin I Level And Its Relation To Severity Of Psoriasis Vulgaris, Aya Hassan Mohammed El-Shamy, Samia Mohammed Abdel Naby, Mohammed Fawzy El Sayed, Amany Ragab Youssef Ahmed

Mansoura Medical Journal

Background: Psoriasis is a chronic inflammatory skin disease affecting 2.5% of the worldwide population. Troponin I levels are accompanied by cardiovascular disease (CVD) risk in psoriatic cases. So, this study was conducted to detect serum levels of high-sensitivity cardiac troponin I (HScTnI) in psoriasis vulgaris (PV) cases compared to healthy controls. Methods: This case-control study included 40 cases with PV and 40 healthy subjects as a control group. Disease severity evaluation was conducted by using the psoriasis area severity index (PASI) score to classify the cases into groups according to severity. Measurement of HScTnI levels was conducted. Results: Mean HsCTn …

Prevalence And Outcome Of Splenic Injury Among Pediatric Trauma Patients, Omar Emad El-Din Bedair Hassan El-Nekity, Magdy Basheer, Amir A. Fikry, Mohamed Shetiwy

Mansoura Medical Journal

Background Pediatric trauma represents a critical public health issue, being the leading contributor of death and long-term disability in this age group. Blunt abdominal trauma is particularly common, with the spleen identified as the most frequently injured organ due to children's distinct anatomical traits. This study aims to detect morbidity, mortality, and complications resulting from splenic injuries in the pediatric population. Patients and methods This observational cross-sectional study was conducted at Mansoura University Emergency Hospital from September 2024 to September 2025. It included 104 pediatric patients with splenic injury out of 3600 pediatric trauma patients. Results The prevalence of splenic …

Role Of Positron Emission Tomography-Computed Tomography (Pet-Ct) In Evaluation Of Hepato-Cellular Carcinoma, Mona Baz, Ahmed Youssef Kandeel, Mohamed Ali El-Adalany, Dina El-Metwally

Mansoura Medical Journal

Background: Globally HCC appeared to be the third main reason of mortality associated with cancer.  According to degree of differentiation, HCC can be classified into four grades. PET/CT represents a functional imaging technique that offers metabolic insights into the tumor. It may play a substantial turn in prediction of biological behavior of HCC, predicting tumor grade and presence of microvascular invasion.

Aim of the work:  This work aimed to assess the utility of 18F-FDG PET/CT in identification of primary hepatocellular carcinoma (HCC) and in predicting its histological grade.

Methods: A total of 52 patients with established HCC were included in …

Epidemiologic, Clinical And Genetic Characteristics Of Familial Mediterranean Fever In Egyptian Children’S Tertiary Care Center, Ghada Ahmed Elsayed Mgahed, Mayada Sabry Zeid, Ali Sobh, Shaltout A

Mansoura Medical Journal

Background: Familial Mediterranean fever (FMF) is an inherited disorder known by recurrent, brief, and self-limiting episodes of fever and serosal inflammation. It is primarily defined by acute inflammatory involvement of serosal membranes, including the pleura, peritoneum, and/or synovial tissues, typically associated by fever. This inflammatory cascade is inherently self-propagating and, if inadequately controlled, may lead to recurrent episodes or sustained inflammatory activity.

Aim of the work: To examine the clinical and demographic characteristics of individuals with childhood- initiation FMF, to determine the prevalence of the most frequent mutations in the FMF-linked gene within this population, and to assess the …

Demographic Characteristics In Patients With Heart Failure And Iron Deficiency, Ahmed Alaa Eldin Abd Elazeem, Abdul Razek Abdul Lateef Maaty, Hanan Ahmed Azzam, Ahmed Mohamed Reda

Mansoura Medical Journal

Background: Iron deficiency (ID) is a major and prevalent comorbidity among heart failure (HF) patients. It is associated with poor exercise tolerance, recurrent hospitalization and higher mortality. Studying patients’ demographics helps to determine vulnerable groups to ID, risk factors and associated comorbidities to be considered during screening and management.

Aim of the Work: To study the demographic characteristics of heart failure patients with iron deficiency.

Patients and Methods: A cross sectional observational study was conducted at a tertiary care university hospital at Delta region of Egypt between year 2024 and 2026. Among 117 HF patients, 100 HF patients …

Predictors Of Outcomes Of Adult Mandibular Fractures: A Prospective Study., Norhan Yahia El-Henawy, Mohamed Ali Mahgoub, Mohamed Radwan El-Hadidy, Ahmed Hassan El-Sabbagh

Mansoura Medical Journal

Background: Mandibular fractures not only cause physical disfigurement and functional impairments but also significantly affect the patient’s psychological, emotional, and social well-being. Predictors are variables that may influence or explain variation in the outcome of mandibular fracture. Aim of work: To evaluate demographic, clinical, radiological, and psychosocial factors associated with early postoperative complications and postoperative depressive symptoms following surgical management of adult mandibular fractures. Methods: A prospective study evaluated patients who will undergo treatment for surgical mandibular fracture/s at Mansoura Emergency Hospital, DK, from August 2023 to July 2024. The patients were assessed by history taking, clinical picture, radiological tools, …

Supporting Latine Older Adults’ Nutrition And Physical Health Goals In Counseling, Zachary P. Mcniece, Jacqueline J. Bergman

Faculty Research, Scholarly, and Creative Activity

Latine older adults face disproportionate risk of chronic nutrition-related conditions and food insecurity, which can exacerbate or contribute to the development of mental health-related concerns. Cultural stigma toward mental illness can result in Latine clients, especially older adults, somatizing symptoms and focusing on physical health goals in counseling. Despite these intersecting needs, counselors often overlook clients’ physical health goals due to limited training and the assumption that medical providers alone should address them. This article advocates integrating basic, culturally responsive nutrition information into counseling practice to support client well-being while staying within the scope of practice. We offer practical recommendations …

Spectroscopic And Structural Characterization Of Unexpected Porphyrinoid Byproducts Resulting From The Reaction Of A Cyclopentadiene Trialdehyde With N-Alkyltripyrranes, Kimberly Le, Gregory M. Ferrence, Timothy D. Lash

Faculty Publications – Chemistry

Acid-catalyzed condensation of N-alkyltripyrranes with a cyclopentadiene trialdehyde, followed by oxidation with aqueous ferric chloride solutions, gave unusual tripyrrolic byproducts in addition to previously reported carbaporphyrins and oxycarbaporphyrins. These stable nonaromatic structures incorporate aldehyde substituents, macrocyclic ketones, two conjugated pyrrole units, and a pyrrolo[1,2-a]pyrrole moiety. The NMR and UV-vis data were consistent with a nonaromatic system, and single-crystal X-ray diffraction confirmed that these structures are highly distorted. Structural characterization of a related aromatic carbaporphyrin triketone was also accomplished.

Detection And Quantification Of Spreading Depolarization In Drosophila Melanogaster Using High-Throughput, Wide-Field Brain Imaging, Wolfgang Stein, Allison L. Harris

Faculty publications – Physics

Spreading depolarization (SD) is a ubiquitous neural phenomenon implicated in mammalian neurological disorders including cerebral ischemia, brain death, stroke, brain injury, and migraine, as well as in insect chill coma. During SD, a breakdown of ion homeostasis and a slowly spreading wave of neural depolarization leads to processing deficits, such as sensory disturbances and paralysis. Our protocols introduce high-throughput techniques using wide-field fluorescence brain imaging in Drosophila melanogaster larvae and adults to detect and quantify the spatial and temporal dynamics of SD and its initiation points. Two SD initiation techniques, rapid cooling and pharmacological manipulation, are detailed. The larval protocols …

A Nuclear Terrorism Scenario: Improvised Nuclear Weapons With 60%-Enriched Uranium, Matt Caplan

Faculty publications – Physics

In this work we show that approximately 60–70 kg of 60%-enriched uranium can be used to build a crude nuclear weapon with a kiloton yield. While too large to fit on a missile, such a weapon could be delivered by a shipping container. This analysis is motivated by the June 2025 Israeli and US attacks on Iran, especially the bombings of the nuclear facilities at Natanz, Fordow and Isfahan. The Iranian stockpile of approximately 440 kg of 60%-enriched uranium is, at the time of writing, inaccessible to IAEA inspectors and stored in secret. The rapid clandestine relocation of this material …

Understanding And Mitigating The Impact Of Childhood Trauma: A Guide For Educators, Kirsten L. Sands

All Electronic Theses and Dissertations

Adverse Childhood Experiences (ACEs) are potentially traumatic experiences that occur during childhood with lasting effects on students’ academic, social, emotional, and behavioral development. Although childhood adversity typically occurs outside of the educational setting, difficulties with emotional regulation, peer relationships, concentration, behavior, and engagement impact education. Teachers are uniquely qualified to observe these behaviors and provide support. However, educators may lack the foundational knowledge and resources necessary to recognize potential signs of adversity. Teachers need foundational information on ACEs, knowledge of potential signs, and how to provide practical, trauma-informed strategies for responding to students who may be experiencing effects of childhood …

Ms Guo Jingjing 郭晶晶女士

Honorary Fellowship 榮譽院士

No abstract provided.

The Territorial Independence Of Intellectual Property Rights, Aaron X. Fellmeth

Chicago Journal of International Law

No abstract provided.

Empowering Students To Engage With Climate Change Action: A Project-Based Module For Artificial Intelligence Literacy And Sustainability Thinking, Gabriel Granco, Yu Chen, Heather Macias, Yunfei Hou, Frank A. Gomez

Faculty Research, Scholarly, and Creative Activity

There is a growing need to prepare students to address complex environmental challenges, particularly climate change and the expanding role of artificial intelligence (AI). This article examines the adaptation of the Artificial Intelligence for Social Good (AI4SG) Ideation module, a pitch- and project-based teaching framework designed to integrate AI literacy and sustainability education. Implemented in an upper division climate change course, the module combines project-based learning, culturally responsive pedagogy, and geographic thinking to guide students in developing community-oriented AI proposals aligned with the United Nations Sustainable Development Goals (SDGs). Students were encouraged to approach their communities not through deficit lenses, …

Comparison Of Mental Illness Comorbidity Pre-Pandemic Vs. Pandemic-Era And Associations With Clinical And Demographic Characteristics For Virginia Public Hospital Inpatient Discharges With A Substance Use Disorder, Marilyn Bartholmae, Tharidu Gunawardena

Department of Medicine Faculty Publications

The rise in mental illnesses after the COVID-19 pandemic is well documented. However, it is not known whether the rates of mental illness comorbidity increased. The objectives of this study were to compare mental illness comorbidity rates before and after the pandemic among inpatients with SUD and to test associations between mental illness comorbidity, physical illness, and demographics. We used a retrospective cross-sectional design in a sample of inpatient discharges (N = 233,017) at Virginia public hospitals from January 2018 to December 2022. We used Z tests to compare rates of mental illness comorbidity pre- and post-pandemic and Chi-square tests …

Criterion Validity Of The Functional Status And Pain Assessment Scale Versus Pain And Length Of Stay In Hospitalized Adults With Scd, Wally R. Smith, Daniel M. Sop, Yue May Zhang, Margaret S. Guy, Rehan Qayyum

Department of Medicine Faculty Publications

Objectives

In prior research we demonstrated face, construct, discriminant, and preliminary convergent validity of the newly developed, 10-item Functional Status Pain Assessment (FSPA) scale (0-50) in adult SCD patients hospitalized with VOC. We aimed in this study to further demonstrate criterion validity of the FSPA.

Methods

This was a prospective observational study of 561 daily functional and pain assessments from 91 hospitalized adults with SCD from January 2018 to June of 2019. Principal Component Analysis (PCA) Partial Least Squares (PLS) models determined the relationship between LOS, pain intensity, and FSPA. A Generalized Linear Model (GLM) to quantified the impact of …

Persistent Hypoxemia On Home Sleep Apnea Testing Prompting Further Evaluation For Pulmonary Embolism: A Case Report, Kyle Admire, Andrew Githaiga

Department of Medicine Faculty Publications

Obstructive sleep apnea is a condition characterized by recurrent upper airway collapse during sleep, which may be associated with sleep disruption and repetitive oxygen desaturations. It is diagnosed by nocturnal in-lab polysomnography or home sleep apnea testing. We present a case of an otherwise healthy individual who had home sleep apnea testing that revealed persistent, unexplained hypoxemia which, on further investigation, was found to be due to a saddle pulmonary embolism.

Enlarging Fingertip Nodule Mimicking A Pyogenic Granuloma In A Man In His 60'S, Avery H. Seward, Jocelyn H. Larocque, Stephen M. Hughes

Department of Medicine Faculty Publications

[Case presentation] A man in his 60's with a history of hypertension, hyperlipidemia, and resected colon cancer in remission presented with a 4-month history of an enlarging nodule on the right fourth fingertip. The patient recalled having a splinter removed from the same site a few weeks prior to the development of the lesion. The lesion was initially diagnosed by an orthopaedist as a pyogenic granuloma (Figure 1a), and the patient was advised to apply table salt to the area several times daily. However, the lesion continued to enlarge over 3 months with occasional bleeding and mild tenderness. Physical examination …

International Myositis Assessment And Clinical Studies Guidelines For Risk-Based Cancer Screening: An External Validation In Patients With Dermatomyositis Seen At A Metropolitan Academic Center, Isabel Silva, Jasper Dayanan, Alexandra Nigro, Capriana Jiang, Ma Georgina Erfe, Trixie Rivera, Saakshi Khattri

Department of Medicine Faculty Publications

Objective

Dermatomyositis (DM) is an idiopathic inflammatory myopathy (IIM) characterized by muscle weakness, skin findings, and increased malignancy risk. Cancer risk is greatest in the three years before or after DM onset, termed paraneoplastic DM. The International Myositis Assessment and Clinical Studies Group (IMACS) set forth evidence-based guidelines for risk stratification and cancer screenings for newly diagnosed patients with IIM. '

Methods

We retrospectively reviewed the records of 413 patients with a known diagnosis of DM or clinically amyopathic DM at the Mount Sinai Health System (2019-2024). Demographics, clinical findings, laboratory results, myositis autoantibody panels, and cancer screening or diagnosis …

Regional Pain Is Associated With Functional Performance In People With Parkinson's Disease, Ryan P. Duncan, Monica R. Hendricksen, Luke Ekdahl, Kevin Smaller, Benjamin Friedman, Miriam R. Rafferty

Department of Medicine Faculty Publications

Background and Purpose:

Little is known about how pain influences physical function in people with mild Parkinson disease (PwPD). The purpose of this study was to investigate the association between physical function and pain presence, location, and intensity in PwPD who were evaluated in an early physical therapy program.

Methods:

Retrospective cross-sectional analysis of electronic medical records from patients with PD evaluated at a single center (2016-2023). Pain presence, location, and intensity (0-10 scale) were recorded at the initial physical therapy evaluation. Functional outcomes included 5-time sit-to-stand, 10-meter walk test, 6-minute walk test, timed up and go, mini-BESTest, and Functional …

Microplastics, Nanoplastics, And Obesity: Current Evidence And Biological Mechanisms, Maram Albandak, Sanam Rabeeah, Ahmad Mahdi Zahidi, David A. Johnson

Department of Medicine Faculty Publications

Obesity is a rapidly growing global health concern. The pathogenesis is complex and cannot be fully explained by lifestyle factors alone. The increasing attention towards this concern has finally been directed towards environmental contributors which may influence metabolic regulation. Microplastics and nano-plastics (MNPs) are ubiquitous environmental pollutants that have recently been detected in food, drinking water, air, and human biological samples, raising concerns about their potential role in metabolic disorders, including obesity. Chronic exposure to MNPs may interfere with metabolic homeostasis through multiple biological pathways. Emerging evidence, including both experimental and animal studies, reports alterations in lipid metabolism, body weight, …

Drug-Induced Lichen Planus Associated With Ocrelizumab, Avery Seward, John D. Strickley, Jeffrey P. Callen

Department of Medicine Faculty Publications

This case report highlights recurrent cutaneous lichen planus as a rare adverse effect of ocrelizumab, with flares occurring after each infusion and improving with prophylactic prednisone. Recognizing this association may help clinicians diagnose and manage similar cases while allowing patients to continue an otherwise effective therapy.

Comparing Pre-Occupational Therapy Student Intercultural Competence Through Local And Global Service Learning, Leah S. Dunn, Diane Ceo-Difrancesco

Journal of Occupational Therapy Education

This study examined undergraduate pre-occupational therapy student intercultural competence (ICC) development through a local or global service-learning experience. Using a mixed-method approach, responses to the Inventory for Assessing the Process of Cultural Competence among Healthcare Professions-Student Version (IAPCC-SV) were compared as well as a content analysis of student essays before and after the service-learning experience to determine ICC growth. Both groups demonstrated ICC growth, but global participants continued their development past the experience. Student essays revealed themes of dissonance, reflection, transformation, and advocacy, with local students focusing on clients and global students adopting broader advocacy goals. Immersive experiences in occupational …

How Do Students Come Across Occupational Therapy And What Makes Them Want To Study Occupational Therapy? Implications For Recruitment, Mette Eg Bruun, Mette Krohn, Sofie Balle Riis, Lene Tanggaard, Tina Helle

Journal of Occupational Therapy Education

Recruitment challenges in occupational therapy education vary globally. To address workforce needs, it is necessary to examine the factors influencing students’ decisions to pursue occupational therapy. This study investigated how students discovered occupational therapy, what they found appealing about the profession, the influence of study location, and demographic differences between students enrolled in an urban university city and a rural district. Three focus group interviews with 15 occupational therapy students were conducted, supplemented by descriptive statistics comparing student characteristics across urban and rural programs. Qualitative analysis identified five categories: (1) discovering occupational therapy by chance, (2) the power of occupational …

Balancing Acts: Exploring Chronic Illness’ Impact On Achievement In Graduate Health Education, Olivia J. Fulton, Lizeth S. Iboy, Bonnie Decker

Journal of Occupational Therapy Education

Graduate students with chronic illness encounter barriers as they navigate graduate programs to achieve their personal goals. Chronic illnesses are often invisible, which makes it more challenging to navigate the educational system. This study aimed to understand participants’ ability to engage in their academic environment and how the severity of their symptoms related to their diagnosis impacted participation in lectures, laboratory activities, exams, and competencies. Nineteen participants completed the online survey with questions regarding demographics and perception of how their condition impacted their academic performance on their best days versus worst days. Three assessment tools were incorporated into the survey: …

A Rasch Analysis Of The Self-Assessment Scale Of Clinical Reasoning In Occupational Therapy (Sa-Crot) For Continuing Professional Development, Sho Maruyama, Reiko Miyamoto, Takuya Hirose, Takao Kaneko, Peter Bontje

Journal of Occupational Therapy Education

The purpose of this study was to establish structural validity, internal reliability, and concurrent validity of the Self-Assessment scale of Clinical Reasoning in Occupational Therapy (SA-CROT) when used in continuing professional development. We conducted a cross-sectional survey of 513 occupational therapists with ≤5 years of experience. Rasch analysis was applied to assess structural validity (rating scale functioning, monotonicity, dimensionality, item/person fit) and reliability (item/person reliability, strata). Additionally, concurrent validity was examined by Spearman’s correlation with clinical experience. The Rasch rating scale analysis supported the structural validity of the SA-CROT. Categories showed ordered thresholds with outfit mean-square (MnSq) values ranging from …

From Classroom To Care: A Pilot Level I Fieldwork Experience Building Acute Care Self-Efficacy, Hannah Y. Oldenburg, Jennifer Bergstrom, Traci Kruse, Tamra Trenary, Corey Mcgee

Journal of Occupational Therapy Education

Level I fieldwork provides an opportunity for occupational therapy students to be exposed to the occupational therapy framework and process across various practice settings. This study addresses a gap in the literature regarding introductory fieldwork experiences for occupational therapy students in complex medical settings, specifically acute care. Researchers implemented a seven-week Level I fieldwork experience at two Midwest trauma centers, utilizing a mixed-methods, two-cohort design with 12 students and 16 practitioners. The program featured a blended Level I fieldwork supervision model, combining faculty-led and traditional on-site supervision. Over the seven-week period, students showed significant improvement in their perceived self-efficacy regarding …

Validity And Reliability Of The Professional Belonging Scale For Occupational Therapy Students Version 2, Sarah Corcoran Otd, Otr/L, Pooja Patel Drot, Otr/L, Izabela Dubiel Drot, Otr/L, Theresa Rhett-Davis Edd, Otr/L, Nancy Green Ms, Drot, Otr/L, Emily Pasqualetto Drot, Otr/L, Amanda Carter Drot, Otr/L

Journal of Occupational Therapy Education

A strong sense of belonging supports student engagement, motivation, clinical competency, retention, and overall well-being; yet few tools specifically assess this construct in occupational therapy (OT) and occupational therapy assistant (OTA) programs. To address this gap, Corcoran et al. (2025) developed the Professional Belonging Scale for Occupational Therapy Students (PBSOTSv1). The current study aimed to revise the PBSOTSv1 for clarity, inclusivity, and alignment with emerging theoretical frameworks and to evaluate the revised version (PBSOTSv2) for content validity and internal consistency reliability. Revisions involved expert cognitive interviews and Content Validity Index (CVI) ratings, guided by Allen et al.’s framework of belonging, …

Generative Artificial Intelligence Application In Occupational Therapy Education, James Wersal, Justin Mason, Mary Shotwell

Journal of Occupational Therapy Education

Generative artificial intelligence (GenAI) is a developing technology within Higher Education Institutions with substantial potential to transform teaching pedagogy, improve individualized learning experiences, and automate administrative functions. GenAI has the potential to bring significant enhancements by advancing adaptive learning interfaces, customized learning materials, and automate administrative support. Despite these benefits, ethical considerations, data privacy, and the risk of over-reliance should be considered prior to using GenAI. The authors highlight how GenAI is supported by adult learning theory and provide practical strategies for incorporating GenAI in the occupational therapy curricula and to support the faculty role. The impact of GenAI on …

The Psychosocial Occupational Therapy Competency Assessment, Revised- Pot-Ca(R), Jenna C. Yeager, Derek Piggott

Journal of Occupational Therapy Education

The Psychosocial Occupational Therapy Competency Assessment (POT-CA) was originally published in 2017 as a framework for assessing student development of foundational skills in evaluation, clinical reasoning, and therapeutic interactions in an occupational therapy psychosocial theory and practice course. The COVID-19 global pandemic necessitated the adaptation of this final student competency assessment for virtual administration. The Canadian Occupational Performance Measure (COPM) was selected as the performance-based element of the competency assessment in lieu of the previously required Allen Cognitive Level Screen (ACLS-5), which was unavailable to students due to pandemic restrictions. The purpose of this article is to present an analysis …