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Embodying Policy Work: An Exploration Of Contexts, Actions And Meanings Towards New Possibilities For Physical Education Teacher Education (Pete), Victoria Evans, David Aldous, Dawn Penney Jan 2026

Embodying Policy Work: An Exploration Of Contexts, Actions And Meanings Towards New Possibilities For Physical Education Teacher Education (Pete), Victoria Evans, David Aldous, Dawn Penney

Research outputs 2022 to 2026

This theoretical paper presents a heuristic framework that is directed towards transformative thinking and practices in Physical Education Teacher Education (PETE). The research focus and direction, embodying policy work, applies and extends Bernstein’s concepts of the pedagogic and corporeal device to offer new directions for inquiry and explore the considerations these raise for PETE professionals and their practices. The paper affirms the importance of policy work in PETE, while recognising a need for more nuanced and critical understandings of the complex interrelationships between contexts and actions, and the potential meanings generated and ascribed to different forms of policy work and …


Gastronomy Tourism Destinations: Developing A Scale To Measure Tourists’ Perceived Attributes, Ganghua Chen, Jingmei Xu, Songshan (Sam) Huang Jan 2026

Gastronomy Tourism Destinations: Developing A Scale To Measure Tourists’ Perceived Attributes, Ganghua Chen, Jingmei Xu, Songshan (Sam) Huang

Research outputs 2022 to 2026

Purpose: This study emphasizes the growing significance of destination attributes in shaping the experiences and behaviours of gastronomy and culinary tourists. Understanding both core and complementary attributes of a gastronomy tourism destination is crucial for its sustainable development. However, there is a lack of a reliable measurement for tourists’ perceived attributes of gastronomy tourism destinations (PAGTD). Therefore, the purpose of this study is to develop a scale to measure tourists’ PAGTD. Design/methodology/approach: The study systematically followed the scale development and validation process, using three samples (Sample 1, n = 200; Sample 2, n = 204; and Sample 3, n = …


Australian University Websites As Colonialities Of Gender, Emily M. Gray, Ampersand Pasley, Emma Fishwick, Mindy Blaise, Jacqueline Ullman, Maria Delaney Jan 2026

Australian University Websites As Colonialities Of Gender, Emily M. Gray, Ampersand Pasley, Emma Fishwick, Mindy Blaise, Jacqueline Ullman, Maria Delaney

Research outputs 2022 to 2026

This paper offers analysis of the first phase of a research project, Understanding and Addressing Everyday Sexisms in Australian Universities. This phase involved a critical content analysis of all 39 of Australia’s public university websites, focusing on how they represent gender, absences in relation to gender and the navigability of the websites in relation to gender equity policy. Drawing on Maria Lugones’s colonialities of gender, this paper demonstrates how university websites have the potential to reproduce or renegotiate inherited institutional everyday sexisms and broader gender inequities. Themes of reconfiguring acceptable gendering, conspicuous absences, and in-built obscurity that emerged from this …


The Role Of Games In Hospitality Management Education, Arghavan Hadinejad, Samira Zare Jan 2026

The Role Of Games In Hospitality Management Education, Arghavan Hadinejad, Samira Zare

Research outputs 2022 to 2026

Building upon game-based learning, this study compares hospitality students’ cognition, metacognition, engagement, satisfaction, and performance in a course across two academic terms at an Australian university. One term featured teaching content without any games while the second term incorporated gamification. A quasi-experimental design was used in which surveys, interviews and students’ evaluation reports were utilized. Students demonstrated more favorable cognitive thoughts, and higher levels of engagement and satisfaction in the gamified course. Students’ performance in assessments across the two courses as well as their metacognition were found to be similar. This study presents a game effectiveness matrix with Kahoot as …


Ensuring That Marginalized Young People Feel Welcome, Understood, And Empowered In Health Services: A Qualitative Examination Of The Service Needs Of Aboriginal Lgbtqa+ Young People, Shakara Liddelow-Hunt, Ashleigh Lin, Yael Perry, Braden Hill, Bep Uink Jan 2026

Ensuring That Marginalized Young People Feel Welcome, Understood, And Empowered In Health Services: A Qualitative Examination Of The Service Needs Of Aboriginal Lgbtqa+ Young People, Shakara Liddelow-Hunt, Ashleigh Lin, Yael Perry, Braden Hill, Bep Uink

Research outputs 2022 to 2026

A lack of appropriate care and discrimination in healthcare settings likely compounds the existing risks to mental health and well-being for Aboriginal and Torres Strait Islander lesbian, gay, bisexual, trans, queer/questioning, and asexual (LGBTQA+) young people. The current study contributes findings from Aboriginal LGBTQA+ young people’s perspectives on their health service needs and preferences. Data consists of qualitative interviews and focus groups with N = 14 Aboriginal LGBTQA+ young people aged 14–25 years in Boorloo (Perth), Western Australia. The data was analyzed using reflexive thematic analysis. Analysis identified three major themes: (1) Unmet need for “whole self” care, (2) Communicating …


Antecedents Of Emergency Services’ Street Level Bureaucrats’ (Slbs) Delivery Of Public Value: An Exploratory Study, Yvonne Brunetto, Ben Farr-Wharton, Aglae Hernandez Grande, Fleur Sharafizad, Matthew Richman Jan 2026

Antecedents Of Emergency Services’ Street Level Bureaucrats’ (Slbs) Delivery Of Public Value: An Exploratory Study, Yvonne Brunetto, Ben Farr-Wharton, Aglae Hernandez Grande, Fleur Sharafizad, Matthew Richman

Research outputs 2022 to 2026

Street Level Organisations (SLOs) determine the Psychosocial Safety Climate (PSC) in their workplaces and we examine pathways from SLBs’ PSC and Public Service Motivation (PSM) to discretionary power, work stress, wellbeing and the subsequent delivery of public value. The structural equation modelling results from 195 Australian police, fire, ambulance, and emergency services workers indicate that PSC had a more significant role in explaining SLBs’ delivery of public value compared with PSM. The implication is that SLOs’ management must ensure psychosocially safe and supportive workplaces conducive to building SLBs’ wellbeing, because that is the pathway for delivering public value.


Care-Full Climate Justice Organising, Kylie Wrigley Jan 2026

Care-Full Climate Justice Organising, Kylie Wrigley

Research outputs 2022 to 2026

Feminist, Indigenous, and disability theories and activisms have long called for more attention to care–both as an ethic and practice–in response to environmental and social issues. Although care work is vital for collective survival, it is relatively devalued and trivialised in society and under-examined in climate justice research. Emerging critical research suggests that care work is central to how climate justice communities understand and respond to climate change and interlocking structural violences. Yet, there is limited climate justice scholarship that attends to the intersections of care and climate movements. At this juncture, this article draws on empirical reflections from a …


Christianity As Coping Mechanisms For Migrants With Mental Health Challenges In Australia: Social Work Implications, Obed Adonteng-Kissi, Nnaemeka Meribe, Kathomi Gatwiri, Lillian Mwanri, Agness Tembo, Frank Darkwa Baffour, Edith N. Botchway-Commey, Aunty Kerrie Doyle, David Chisanga, Ahmed A. Moustafa, Uchechukwu Levi Osuagwu Jan 2026

Christianity As Coping Mechanisms For Migrants With Mental Health Challenges In Australia: Social Work Implications, Obed Adonteng-Kissi, Nnaemeka Meribe, Kathomi Gatwiri, Lillian Mwanri, Agness Tembo, Frank Darkwa Baffour, Edith N. Botchway-Commey, Aunty Kerrie Doyle, David Chisanga, Ahmed A. Moustafa, Uchechukwu Levi Osuagwu

Research outputs 2022 to 2026

Christian religion may be a powerful resource that can serve as a coping mechanism to resolve challenges and provide comfort to African migrants confronted with mental health challenges. We aimed to explore the coping strategies among African migrants in Australia. We undertook semi-structured interviews online with 11 participants with African backgrounds, comprising six mental health clinicians and five migrant service users living in Australia for at least the past 12 months. Literature exploring religious coping mechanisms, social support and acculturation was drawn on. The interviews were undertaken online via Teams, WhatsApp call, and zoom with participants whom we recruited through …


Stakeholder Perceptions Of The Feasibility Of E-Portfolio-Based Assessment Of Physical Literacy In Primary Health And Physical Education, Jaxon Hogan, Dawn Penney, Eibhlish O’Hara, Joseph Scott Jan 2026

Stakeholder Perceptions Of The Feasibility Of E-Portfolio-Based Assessment Of Physical Literacy In Primary Health And Physical Education, Jaxon Hogan, Dawn Penney, Eibhlish O’Hara, Joseph Scott

Research outputs 2022 to 2026

Background: Physical literacy (PL) is widely acknowledged as an integral component of high-quality physical education programmes. However, what constitutes appropriate assessment of PL remains a contested issue. This study drew on Whitehead’s conceptualisation of PL as a lifelong journey and investigated how primary school teachers can support students’ PL learning through innovative and engaging assessment methods. The study specifically examined the feasibility of using e-portfolios to facilitate quality PL learning and quality assessment in Physical Education (PE), from different stakeholder perspectives. Methods: This interpretive study employed a qualitative design and methods to investigate aspects of feasibility with three purposive participant …


From Perspectival Myopia To Professional Transformation: An Autoethnographic Retrospection Of A High School Principal From Nepal, Shankar Dhakal, Geoffrey W. Lummis, Andrew Jones Jan 2026

From Perspectival Myopia To Professional Transformation: An Autoethnographic Retrospection Of A High School Principal From Nepal, Shankar Dhakal, Geoffrey W. Lummis, Andrew Jones

Research outputs 2022 to 2026

This paper presents a re-storied account of my (lead author) decade-long (2007–2017) professional journey as a high school principal in diverse educational settings in Nepal. Using an autoethnographic approach, I have theorized my leadership transformation approaches through professional storytelling, employing critical reflexivity to trace intimate leadership experiences where authoritarian approaches to leadership, disparities, and inequalities in schools run rampant. My perspectival myopia, professional vulnerabilities, and the discrepancies between my leadership ideals and behaviors resulted in issues such as perceptions of disengagement, underperformance, and dissatisfaction on the receiving end, prompting me to contemplate professional transformation. While outlining several significant steps and …


Comparative Analysis Of Ev-Charging Converters Using Silicon Carbide Mosfets And Silicon Igbt’S, Muhammad A. Kahn Jan 2026

Comparative Analysis Of Ev-Charging Converters Using Silicon Carbide Mosfets And Silicon Igbt’S, Muhammad A. Kahn

Electrical Engineering Theses

The rapid expansion of electric vehicle (EV) charging infrastructure has increased the demand for efficient and reliable power electronic converters. Semiconductor device selection is critical to system performance, influencing efficiency, power density, and reliability. This thesis presents a comparative analysis of Silicon (Si) Insulated Gate Bipolar Transistors (IGBTs) and Silicon Carbide (SiC) MOSFETs in a representative EV charging converter, with emphasis on electrical performance and thermal behavior under identical operating conditions.

The research employs PLECS (Plexim) and electro-thermal simulation models to accurately characterize device and system interactions. The converter configuration consists of a grid-connected voltage source inverter (VSI) that maintains …


The Manifestation Of Antihaitianismo In Abinader’S Dominican Political Atmosphere, Isabella Alcantara Jan 2026

The Manifestation Of Antihaitianismo In Abinader’S Dominican Political Atmosphere, Isabella Alcantara

FCRH Honors Program Theses

In the past decade, Haitian migration has become central to Dominican political discourse. This shift is particularly evident under President Luis Abinader’s administration, which has overseen a sharp increase in restrictive border enforcement and citizenship measures targeting Haitian migrants fleeing escalating humanitarian crises. While existing scholarship on Dominican nationalism highlights the historical role of antihaitianismo in shaping exclusionary state practices, less attention has been paid to how contemporary elite rhetoric reproduces these dynamics in more indirect, coded ways. Drawing on theories of symbolic politics and securitization, this study examines how state discourse constructs Haitian migrants within national narratives. It asks: …


The Long Life Of Illumination: How Medieval Manuscripts Shaped Modern Print Culture, Malena Sullivan Jan 2026

The Long Life Of Illumination: How Medieval Manuscripts Shaped Modern Print Culture, Malena Sullivan

FCRH Honors Program Theses

Design is everywhere in our lives, from product and book layouts to advertisements and the web. Design packages information into visually appealing formats which grab attention and relate an easily understood message. Through fonts, illustrations, patterns, and color, good design does more than just convey information. Rather, it is an art form in itself that has the power to stay within the viewer’s imagination through impactful visuals. The act of designing is a creative process, but also one that often borrows from the past. Before printing was widely adopted in Europe in the fifteenth century, books were written out and …


Dual Targeting Of Amrc12 And Malassezia Globosa Disrupts Myc Liquid Condensates-Driven Nuclear Pore Complex Biogenesis In Neuroblastoma, Anpei Hu, Chunhui Yang, Zhijie Wang, Xiaolin Wang, Xinyue Li, Shunchen Zhou, Bosen Zhao, Jiaying Qu, Xiaojing Wang, Liduan Zheng, Qiangsong Tong Jan 2026

Dual Targeting Of Amrc12 And Malassezia Globosa Disrupts Myc Liquid Condensates-Driven Nuclear Pore Complex Biogenesis In Neuroblastoma, Anpei Hu, Chunhui Yang, Zhijie Wang, Xiaolin Wang, Xinyue Li, Shunchen Zhou, Bosen Zhao, Jiaying Qu, Xiaojing Wang, Liduan Zheng, Qiangsong Tong

Faculty, Staff and Students Publications

Rationale: Neuroblastoma (NB) is a predominant extra-cranial malignancy in childhood, while molecular drivers of its progression and effective treatment strategies have yet to be clarified.

Methods: RNA sequencing was performed to identify transcriptional regulators and corresponding target genes. To explore the biological effects and underlying mechanisms of these regulators, a comprehensive methodology was utilized, encompassing chromatin immunoprecipitation, dual-luciferase reporter assay, qRT-PCR, western blot, alongside gene over-expression and silencing techniques, co-immunoprecipitation, and mass spectrometry. The MTT assay, soft agar colony formation, Matrigel invasion, and nude mouse xenograft models were applied to assess oncogenic properties. Patient survival was analyzed using the log-rank …


Findings And Recommendations From The State Of The Art (Sota) Conference On Nursing Research To Improve Veteran Outcomes, Amelia E Schlak, Sarah Krein, Laura A Petersen, David Atkins, Catherine Battaglia, Elizabeth Burkhart, Renee Colsch, Marguerite Daus, Heather Gilmartin, Nipa Kamdar, Melissa Knox, Ann Kutney-Lee, Christine M Olney, Kathryn Rugen, Tracy Weistreich, Sheila Cox Sullivan, On Behalf The Nursing Sota Planning Committee Jan 2026

Findings And Recommendations From The State Of The Art (Sota) Conference On Nursing Research To Improve Veteran Outcomes, Amelia E Schlak, Sarah Krein, Laura A Petersen, David Atkins, Catherine Battaglia, Elizabeth Burkhart, Renee Colsch, Marguerite Daus, Heather Gilmartin, Nipa Kamdar, Melissa Knox, Ann Kutney-Lee, Christine M Olney, Kathryn Rugen, Tracy Weistreich, Sheila Cox Sullivan, On Behalf The Nursing Sota Planning Committee

Faculty, Staff and Students Publications

The Veterans Health Administration (VHA), the largest employer of nurses in the United States, has more than 120,000 nursing personnel providing care to over 9 million Veterans across diverse settings. Despite nursing's central role in delivering and sustaining care, research on strengthening the nursing workforce and optimizing nursing practice has remained underdeveloped in VHA. To address this gap, VHA's Office of Research and Development, in partnership with the Office of Nursing Services, convened a State of the Art (SOTA) conference in November 2023 focused on nursing. The Nursing SOTA brought together nurses, researchers, operational leaders, and other stakeholders to review …


Assessment Of In-Frame Indel Variants In An Unsolved Cohort Of Inherited Retinal Diseases Using Machine Learning, David E Rauch, Meng Wang, Muhammad Jafar Hussain Hafiz, Daniel C Brock, Yumei Li, Molly Marra, Mark E Pennesi, Paul Yang, Everett Lesley, Irma Lopez, Robert Koenekoop, Edward Ryan Collantes, Joanne Bolinao, Rui Chen Jan 2026

Assessment Of In-Frame Indel Variants In An Unsolved Cohort Of Inherited Retinal Diseases Using Machine Learning, David E Rauch, Meng Wang, Muhammad Jafar Hussain Hafiz, Daniel C Brock, Yumei Li, Molly Marra, Mark E Pennesi, Paul Yang, Everett Lesley, Irma Lopez, Robert Koenekoop, Edward Ryan Collantes, Joanne Bolinao, Rui Chen

Faculty, Staff and Students Publications

The standard for in silico pathogenicity prediction of in-frame insertions and deletions (indels) is less established compared to other types of variations. We aimed to systematically assess the performance of in silico machine learning (ML) tools on a patient cohort with inherited retinal diseases (IRDs). The performance of four ML tools (CADD, FATHMM-indel, VEST4, and MetaRNN-indel) was compared. Among them, MetaRNN-indel showed the best overall results. MetaRNN-indel was then applied to 1013 unsolved IRD patients, identifying two likely pathogenic causal variants in two unrelated IRD patients by confirming clinical phenotypes. Hence, our findings indicate that reliable prediction of the pathogenicity …


Strategies And Challenges For The Recruitment Of Young Healthy Participants In The Dietary Approaches To Longevity And Health (Dial Health) Pilot Trial, Hannah E Cabre, Courtney M Peterson, Gareth R Dutton, Kimberly L Drews, Stephanie T Broyles, Robert Dubin, Laura Q Rogers, Catherine Champagne, Dennis T Villareal, Daniel S Hsia, Leanne M Redman, Corby K Martin Jan 2026

Strategies And Challenges For The Recruitment Of Young Healthy Participants In The Dietary Approaches To Longevity And Health (Dial Health) Pilot Trial, Hannah E Cabre, Courtney M Peterson, Gareth R Dutton, Kimberly L Drews, Stephanie T Broyles, Robert Dubin, Laura Q Rogers, Catherine Champagne, Dennis T Villareal, Daniel S Hsia, Leanne M Redman, Corby K Martin

Faculty, Staff and Students Publications

Background: Understanding the impact of nutrition on human aging requires long-term trials in young, healthy, unmedicated adults. As part of the Dietary Approaches for Longevity and Health (DiAL Health) pilot project, we evaluated strategies for recruiting this population for aging-related dietary intervention studies.

Methods: We analyzed recruitment costs to enroll 70 participants (ages 25-49, BMI 22.0-29.9 kg/m2) across two DiAL Health sites and used NHANES data (2017-March 2020) to estimate the proportion of U.S. adults meeting partial trial eligibility. Additionally, a formative study surveyed 492 U.S. adults (≥18 years) to assess interest in aging-focused dietary trials.

Results: Of 2049 applicants …


Sewers To Solutions: A Guide To Wastewater Pathogen Monitoring, Justin R Clark, Anthony W Maresso Jan 2026

Sewers To Solutions: A Guide To Wastewater Pathogen Monitoring, Justin R Clark, Anthony W Maresso

Faculty, Staff and Students Publications

Wastewater-based epidemiology (WBE) is the analysis of wastewater to detect pathogen levels or activity for public health awareness or action. Pioneered in the 1940s, WBE underwent a resurgence during the COVID-19 pandemic, providing important information about number of cases, outbreaks, and seasonal impact. With advancements in detection technologies and growing interest in environmental surveillance, WBE is poised to become a standard practice in public health monitoring. Here, we provide an overview of the current state of the art of pathogen WBE, including methods of molecular detection, analysis of wastewater data, real-world applications and programs, public health interventions, and benefits and …


Lysine Demethylase 4a Is A Centrosome-Associated Protein Required For Centrosome Integrity And Genomic Stability, Pratim Chowdhury, Xiaoli Wang, Richard I Han, Manga Motrapu, Ashley G Boice, Yuya Nakatani, Sofia Vargas-Hernandez, Julia F Love, Claude Chew, Sandra L Grimm, Dereck Mezquita, Frank M Mason, Elisabeth D Martinez, Cristian Coarfa, Cheryl L Walker, Anna-Karin Gustavsson, Ruhee Dere Jan 2026

Lysine Demethylase 4a Is A Centrosome-Associated Protein Required For Centrosome Integrity And Genomic Stability, Pratim Chowdhury, Xiaoli Wang, Richard I Han, Manga Motrapu, Ashley G Boice, Yuya Nakatani, Sofia Vargas-Hernandez, Julia F Love, Claude Chew, Sandra L Grimm, Dereck Mezquita, Frank M Mason, Elisabeth D Martinez, Cristian Coarfa, Cheryl L Walker, Anna-Karin Gustavsson, Ruhee Dere

Faculty, Staff and Students Publications

Centrosomes play a fundamental role in nucleating and organizing microtubules in the cell and are vital for faithful chromosome segregation and maintenance of genomic stability. Loss of structural or functional integrity of centrosomes causes genomic instability and is a driver of oncogenesis. Here we identify lysine demethylase 4A (KDM4A), an epigenetic 'eraser' of chromatin methyl marks, as a centrosome-localized protein, visualized at the nanometer-scale resolution. We additionally uncovered that KDM4A demethylase enzymatic activity is required to maintain centrosome homeostasis and integrity; a previously unknown functionality unlinked to altered expression of genes regulating centrosome number. We find that KDM4A interacts with …


Clinical Factors And Diagnoses Associated With Inappropriate Urine Culture Ordering In Primary Care, Marissa Valentine-King, Barbara W Trautner, Michael A Hansen, Roger Zoorob, Lisa C K Danek, Kenneth Muldrew, Forrest Hudson, Robert L Atmar, Larissa Grigoryan Jan 2026

Clinical Factors And Diagnoses Associated With Inappropriate Urine Culture Ordering In Primary Care, Marissa Valentine-King, Barbara W Trautner, Michael A Hansen, Roger Zoorob, Lisa C K Danek, Kenneth Muldrew, Forrest Hudson, Robert L Atmar, Larissa Grigoryan

Faculty, Staff and Students Publications

Objective: Evaluate the prevalence and risk factors for inappropriately ordered urine cultures in primary care.

Design: Cross-sectional study using chart reviews.

Setting: Two primary care, safety-net clinics in Houston, Texas.

Patients: Non-pregnant adults without a urinary catheter who had a urine culture and a primary care visit between 11/2018 and 3/2020.

Methods: We classified patients lacking physician documentation of the following symptoms as having an inappropriately ordered urine culture: dysuria, frequency, urgency, hematuria, fever, chills, costovertebral angle tenderness, nephrolithiasis, and pain (suprapubic, pelvic, or flank). We extracted patient demographics, visit-related diagnostic codes, past medical history, and urine culture results. Diagnostic …


Between Trends And Truths: Tiktok Therapy-Speak And Mental Health, Zoe Stephens Jan 2026

Between Trends And Truths: Tiktok Therapy-Speak And Mental Health, Zoe Stephens

Scripps Senior Theses

The rise of therapy-speak on social media has introduced mental health terminology into everyday discourse among young adults, yet its psychological impacts remain unclear (Chevalier, 2024; Jain et al., 2025). The present study investigated the effects of TikTok videos containing therapy-speak on stigma toward mental illness, mental health awareness, and mental health literacy. Using a between-groups experimental design, 95 U.S. college students aged 18 to 24 were randomly assigned to view either therapy-speak TikTok content or neutral TikTok content. Participants subsequently completed three post-exposure measures: the Mental Health Literacy Scale (MHLS; O’Connor & Casey, 2015), a self-constructed Mental Health Awareness …


End-To-End Development And Experimental Validation Of A 1/10-Scale Autonomous Vehicle, Rikkin Pankaj Panchal Jan 2026

End-To-End Development And Experimental Validation Of A 1/10-Scale Autonomous Vehicle, Rikkin Pankaj Panchal

Electrical Engineering Theses

Autonomous vehicle development demands vast resources, making scaled down platforms a critical alternative for solving core algorithmic challenges. The primary contribution of this thesis is the end to end development and validation of a complete real time autonomous driving pipeline deployed on a one tenth scale vehicle. To streamline platform development, an AI assisted annotation framework automates dataset generation, significantly reducing manual labor while improving training data quality. The system perception stack features a reinforcement learning guided online multi camera calibration framework that enables adaptive surround view stitching without the need for offline recalibration. This is paired with robust lane …


Senolytic-Resistant Senescent Cells Have A Distinct Sasp Profile And Functional Impact: The Path To Developing Senosensitizers, Utkarsh Tripathi, Masayoshi Suda, Vagisha Kulshreshtha, Bryan T Piatkowski, Allyson K Palmer, Nino Giorgadze, Christina Inman, Nathan Gasek, Ming Xu, Kurt O Johnson, Tamar Pirtskhalava, Selim Chaib, Larissa P G Langhi Prata, Yi Zhu, Renuka Kandhaya-Pillai, Stefan G Tullius, Saranya P Wyles, Rambabu Majji, Hari Krishna Yalamanchili, David B Allison, Tamar Tchkonia, James L Kirkland Jan 2026

Senolytic-Resistant Senescent Cells Have A Distinct Sasp Profile And Functional Impact: The Path To Developing Senosensitizers, Utkarsh Tripathi, Masayoshi Suda, Vagisha Kulshreshtha, Bryan T Piatkowski, Allyson K Palmer, Nino Giorgadze, Christina Inman, Nathan Gasek, Ming Xu, Kurt O Johnson, Tamar Pirtskhalava, Selim Chaib, Larissa P G Langhi Prata, Yi Zhu, Renuka Kandhaya-Pillai, Stefan G Tullius, Saranya P Wyles, Rambabu Majji, Hari Krishna Yalamanchili, David B Allison, Tamar Tchkonia, James L Kirkland

Faculty, Staff and Students Publications

The senescent cell (SC) fate is linked to aging, multiple disorders and diseases, and physical dysfunction. Senolytics, agents that selectively eliminate 30%-70% of SCs, act by transiently disabling the senescent cell antiapoptotic pathways (SCAPs), which defend those SCs that are proapoptotic and pro-inflammatory from their own senescence-associated secretory phenotype (SASP). Consistent with this, a JAK/STAT inhibitor, Ruxolitinib, which attenuates the pro-inflammatory SASP of senescent human preadipocytes, caused them to become "senolytic-resistant". Administering senolytics to obese mice selectively decreased the abundance of the subset of SCs that is pro-inflammatory. In cell cultures, the 30%-70% of human senescent preadipocytes or human umbilical …


Corals, Creation, And Conservation: Evaluating Human-Marine Relations Through Coral Reef Biology And Artistic Practice, Emma Gray Garman Jan 2026

Corals, Creation, And Conservation: Evaluating Human-Marine Relations Through Coral Reef Biology And Artistic Practice, Emma Gray Garman

Scripps Senior Theses

This thesis investigates the relationship between humans and marine ecosystems through two complementary lenses: scientific research and artistic practice. The biology chapter proposes a five-year coral reef monitoring study across four Queensland, Australia islands — two heavily visited and inhabited (Fitzroy and Green Islands) and two minimally visited and uninhabited (High and Woody Islands) — to assess whether human activity correlates with bleaching severity over time. Grounded in preliminary survey data from Green Island in 2024, which revealed approximately 54% of coral bleached or dead, the study hypothesizes that reefs adjacent to inhabited islands will exhibit greater bleaching severity, consistent …


Spectral Decimation On The Schreier Graphs Of The Basilica Group: A Thesis In Fractal Analysis, Anne D. Bannon Jan 2026

Spectral Decimation On The Schreier Graphs Of The Basilica Group: A Thesis In Fractal Analysis, Anne D. Bannon

Scripps Senior Theses

This thesis is intended to provide a comprehensive overview of the literature required to fully understand research conducted during the University of Connecticut's Fractals & Stochastics REU in the summer of 2025. The literature review includes a description of Robert Strichartz's seminal work pertaining to the Laplacian spectrum of the Sierpiński Gasket, which provides a framework for how we approach studying the spectrum of the basilica Julia set. Defining the basilica Julia set and the closely-related Basilica group involves graph theory, automata theory, iterated monodromy group theory, and amenable group theory. Further time is dedicated to defining the graph Laplacian …


Appalachia In Presidential Campaign Rhetoric Since 1964, Meredith Morello Jan 2026

Appalachia In Presidential Campaign Rhetoric Since 1964, Meredith Morello

Scripps Senior Theses

This thesis examines how presidential candidates have invoked Appalachia in campaign rhetoric from Lyndon B. Johnson's 1964 election through 2024, arguing the region functions not as a geographic reference but as a strategically deployable political symbol. Through mixed-methods analysis of 83 campaign-period sources archived in the American Presidency Project, a structured thematic coding schema traces how candidates frame the region across six decades using two analytically distinct modes: objective-economic and moralized-culture framing.

Five major structural patterns emerge: Johnson's institutionalization of the region as bounded domestic poverty; strategic silence during national instability; reframings enabling rhetorical reentry; symbolic portability across ideological projects; …


Making Faces, Elinor Attisani Jan 2026

Making Faces, Elinor Attisani

Scripps Senior Theses

Making Faces critiques the naturalization of gender norms and asserts that all gender expression is learned and imitative. With respect to my work, “naturalization” refers to the attribution of patterns of behavior to an unbreakable essence at the core of a person; the distinct qualities that place masculinity and femininity in opposition are often attributed to natural characteristics of the male and female sexes. Judith Butler famously contradicts this myth of gender expression as the externalization of an underlying core identity in their book, Gender Trouble, where they argue that the repeated imitation of a nonexistent ideal is constitutive of …


Modeling French Language Preservation: An Optimal Control Problem, Charlotte Blasi Jan 2026

Modeling French Language Preservation: An Optimal Control Problem, Charlotte Blasi

Scripps Senior Theses

The French language is one of the most globally spoken languages, with over 300 million speakers and designated the official language of 29 nations. French continues to prosper as a result of its titular nations' imperialist history that emphasized linguistic diffusion as well as the support of international organizations dedicated to promoting both the language and the culture of French-speaking nations. In this thesis, we explore the nuanced history of French-speaking countries and one institution dedicated  to promoting the French language, the OIF. We further examine the media mechanism of the OIF and construct a system of Ordinary Differential Equations …


From South Korea To South Central: The 1992 Los Angeles Uprising And The "Rooftop Korean", Mina Althea Lamson Jung Jan 2026

From South Korea To South Central: The 1992 Los Angeles Uprising And The "Rooftop Korean", Mina Althea Lamson Jung

Scripps Senior Theses

This thesis examines the historical formation of the "rooftop Korean," the racial figure of the armed Korean American shopkeeper that emerged during the 1992 Los Angeles Uprising and has since been mobilized repeatedly in service of anti-Black counterinsurgency. Drawing on the framework of racial capitalism, this thesis argues that the rooftop Korean was not a spontaneous product of the Korean-Black conflict in South Central Los Angeles but the culmination of decades of U.S.-Korea relations, South Korean militarization, and the racial geography of capitalist development on both sides of the Pacific.

Tracing a transnational arc from the Korean War through the …


The Split Child: Fragmented Temporalities And Selves In Post-Francoist Horror Cinema, Harper A. Denniston Jan 2026

The Split Child: Fragmented Temporalities And Selves In Post-Francoist Horror Cinema, Harper A. Denniston

Scripps Senior Theses

This thesis interrogates the prolific figure of the spectral child in post-dictatorial horror cinema in Spain. During the renaissance wave of the horror boom (a period between the late 1990s and early 2000s that experienced a surge in horror films), narratives of haunting often presented the ghost in child form, blending childhood and horror. This thesis examines the spectral child as depicted in the seminal horror films The Devil’s Backbone (2001) and The Orphanage (2007). First, I establish the historical context behind these films, exploring the traumatic history of children during the Spanish Civil War and Franco dictatorship, Spain’s cultural …