Digital Commons Network^™

In Silico Study Of N-Pyrazoline Derivate Compounds As Anticancer Through Inhibition Of Pi3k And Pr Expression, Denny Satria, Syukur Berkat Waruwu, Eti Nurwening Sholikhah, Mustofa Mustofa, Pamungkas Bagus Satriyo, Tutik Dwi Wahyuningsih, Hesti L Wiraswati, Ema Damayanti

Baghdad Science Journal

Breast cancer treatment has many options directed at therapeutic targets, but some remain incurable, so new therapies are needed. Pyrazoline has shown various biological activities, one of which is anticancer effectiveness. The purpose of this study was to conduct an in silico analysis of Pyrazoline inhibition of PI3K and PR proteins using docking and MD simulation methods. Predictions of toxicity and pharmacokinetics, including absorption, distribution, metabolism, excretion, and toxicity, were also conducted computationally. The analysis showed that the Pyrazoline compound had interactions with ligands of PI3K proteins and PR proteins. Pharmacokinetic predictions showed that the compound in the human intestine …

Determination Of Mebeverine – Hcl Using 3, 5–Dinitrosalicylic Acid And Multiple Continuous Flow Cell That Works As A Solo Flow Cell With 4s×3 – 3d Analyzer, Elham N. Mezaal, Nagam S. Turkey

Baghdad Science Journal

A new method, simple and sensitive was utilized in determining mebeverine – HCl (MB-HCl) (3, 4-Dimethoxy benzoic acid ethyl 2, 4 methoxy4-phenyl-1-methyl ethyl amino-butyl ester) in pure and pharmaceutical formulations via utilization this multiple continuous flow cell. The method is dependent on genesis for complex of ion pair(4-((3, 4-dimethoxybenzoyl) oxy)-N-ethyl-N-(1-(4-methoxyphenyl) propan-2-yl) butan-1-aminium-2-hydroxy-3,5-dinitrobenzoate) among mebeverine–HCl (MB-HCl) and 3,5-Dinitrosalicylic acid (3,5-DNSA) in ammonium acetate middle to configure a whiteish yellow precipitate compound via utilizing multiple continuous flow cell that works as a solo flow cell with 4S×3 – 3D analyzer. Optimum parameters were studied to raise the sensitivity for improving the method. …

A Capability Maturity Model For Artificial Intelligence Integration In Supply Chain Management, Lordt Becklines

Dissertations

Artificial Intelligence (AI) is transforming Supply Chain Management (SCM), yet many organizations struggle to assess their readiness for AI adoption and to understand how AI capabilities develop across maturity stages. This dissertation addresses this gap by developing a Capability Maturity Model (CMM) for AI integration in SCM, grounded in Organizational Information Processing Theory (OIPT), the Resource-Based View, and related capability frameworks. The model provides a structured approach for evaluating an organization's information-processing requirements, resource configurations, and alignment needed for effective AI-enabled supply chain operations.

Using a design science research approach, the AI-SCM CMM and its associated assessment instrument were derived …

Short-Term Spark Or Long-Term Flame? Sustaining Academic Psychiatric Departments, Rohit Shankar, Richard Laugharne, Derek K. Tracy, Dinesh Bhugra

Peninsula Medical School

SummaryOver the past two decades, the number of academic psychiatrists in the UK has declined by more than a third, despite an expansion in medical schools and growth in most other medical academic specialties. Drawing on direct experience of establishing a new academic unit, we argue that the long-term sustainability of academic psychiatry departments is critical for service quality, innovation and talent development. This paper outlines the structural, cultural and strategic factors needed to create academic units that endure and flourish beyond individual careers, enabling better integration of research and clinical practice.

Positional Differences In Internal And External Match-Play Loads Among Njcaa Division Ii Women's Soccer Players, Shannon Baisden

Doctorate in Kinesiology

This study quantified and compared the internal and external match-play demands of female community college soccer players by position during competitive match play. Using a retrospective observational design, GPS- and heart-rate–derived data were analyzed across eight regular-season matches from one NJCAA Division II women's soccer team. Nineteen outfield players were classified as defenders, midfielders, or forwards. Internal load was assessed using heart-rate metrics and time spent in intensity zones, while external load was measured using total distance and proprietary workload metrics. Linear mixed-effects models were employed to evaluate positional differences while accounting for repeated measures. Results revealed clear positional trends …

Re: Approval Letter For The Final Repository Siting Study (Rss) Detailed Evaluation And Recommendations Report (Dated February 11, 2026), Emma Rott

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

Autonomous Aesthetic Composition Via A Generative Model In A Robotic Control Loop, Rohit Sinha, Prathamesh Save, Kumar N. Dwarakanath

Defensive Publications Series

Automated camera systems may focus on geometric tracking without considering aesthetic composition, while certain aesthetic evaluation software may lack the physical agency to move a camera to create an improved image. Disclosed are systems and methods for a closed-loop control architecture that can integrate a mobile robotic platform, such as a drone or wheeled robot, with a generative cognitive agent. Such a system can operate through an iterative cycle where an image can be captured, the agent can provide a natural language critique and a corrective command based on a high-level subjective goal, and a local controller can translate the …

Perencanaan Pemukiman Transmigrasi Sebagai Usaha Pengembangan Wilayah Serta Masalah Hukum Dalam Penyediaan Dan Penyiapan Tanahnya, Arie Sukanti Sumantri, S.H.

Jurnal Hukum & Pembangunan

Abstract

Strategies For Sustainable And Inclusive Outdoor Wayfinding In Healthcare Facilities: An Approach To Enhance User Experience At Kafr Alsheikh University Hospital, Egypt, Rania Abd Allateef Ghanam, Ahmed Salah El-Deep

Mansoura Engineering Journal

Outdoor wayfinding plays a critical role in shaping user experience in healthcare environments, where inadequate navigation can heighten stress and hinder timely access to care. Despite the presence of wayfinding systems in many hospitals, outdoor navigation remains underexamined and inconsistently addressed in design guidelines. This study fills this gap by investigating architectural strategies to enhance outdoor wayfinding and reduce user stress. The research focuses on Kafrelsheikh University Hospital in Egypt and applies a twophase methodology: (1) a comprehensive literature review to identify current principles, guidelines, and best practices in outdoor wayfinding, and (2) an on-site case study to assess existing …

The Impact Of Integrating Social Benefit Requirements For Urban Green Infrastructure And Place Identity Attributes To Enhance The Sense Of Place - Case Study Of Central Park, Madinaty, New Cairo City, Egypt, Ibrahim Magdi Mohammed, Rehab Abdelfatah Abdel Aziz Mahmoud

Mansoura Engineering Journal

This research develops an integrated model that links the social benefit requirements of Urban Green Infrastructure (UGI) with the non-physical attributes of Place Identity (PI) to enhance the Sense of Place (SOP) in contemporary urban environments. The need for this integration arises from limitations in current planning frameworks, which often prioritize ecological performance while overlooking cultural, perceptual, and behavioral dimensions that shape user attachment and belonging. The study adopts an inductive and synthesis-based approach to identify key UGI indicators across environmental, social, economic, and spatial dimensions, alongside PI attributes related to places’ legibility, uniqueness, publicness and territoriality, place’s identification. To …

Enhancing Thermal Energy Storage Efficiency Using Optimized Concrete Materials: A Review, Ahmed Mohamed Abbass, Ahmed M. El-Khayatt, Khaled A. Eltawil

Mansoura Engineering Journal

The increasing global energy demand and the environmental impact of fossil fuels necessitate the development of sustainable energy solutions. Solar energy is a promising alternative, but its intermittency and inefficiency limit its widespread adoption. This study explores the role of advanced concrete-based thermal energy storage systems in addressing these challenges. Key aspects examined include packing density optimization, high-temperature performance, and hydrothermal durability of concrete. The research highlights the importance of granulometric optimization, binder selection, and hydration mechanisms in enhancing concrete properties. Additionally, the effects of heat exposure on concrete durability, permeability, and mechanical strength are analyzed, with a focus on …

Optimized Thermal Management Of Cylindrical Lithium-Ion Batteries Using Circular Fins And Forced Air-Cooling, Mohamed M. Donia, Ahmed A. Hegazi, Mohamed A. Aziz, Osama Abdelrehim

Mansoura Engineering Journal

The Battery Thermal Management System (BTMS) is vital for maintaining the optimal performance, safety, and longevity of electric vehicle batteries by keeping their temperature within a desired range. This study proposes an optimized cooling solution for BTMS based on both experimental and numerical investigations. Experimental tests were performed on a single battery cell under discharging rates of 1C, 2C, 3C, and 4C using an electronic load, with thermal performance evaluated under natural convection. Numerical models simulating both forced and natural convection were developed using ANSYS 19.3, and a combined Computational Fluid Dynamics (CFD) and Response Surface Methodology (RSM) approach was …

Assessing The Geomechanical Modelling Of Underground Reservoir For Co₂ Storage Trapping Mechanisms, Bonavian Hasiholan, Mohammed Ali Farea, Elhassan Mostafa Abdallah, Sami Abdelrahman M. Yagoub, Yasir Mukhtar

Mathematical Modelling and Numerical Simulation with Applications

Effective carbon dioxide (CO₂) storage is essential for mitigating climate change amid increasing global greenhouse gas emissions. This study investigates the influence of geomechanics on CO₂ storage performance within carbon capture and storage (CCS), focusing on structural, residual, and solubility trapping mechanisms using a fully coupled modeling framework. Two numerical models, with and without geomechanical effects, are developed to evaluate impacts on reservoir behavior, CO₂ migration, and trapping efficiency. Each mechanism is analyzed separately and within an integrated framework to assess their combined contributions. Results indicate that geomechanical coupling increases reservoir pressure, reduces CO₂ flow velocity, enhances migration control, and …

A Coupled Fractional Thermistor System Demonstrating Existence, Uniqueness, And Simulation Results With Two-Point Boundary Conditions, Yahia Awad, Angela Khattar, Hussein Fakih, Sami Hammoud, Karim Amin

Mathematical Modelling and Numerical Simulation with Applications

This paper studies a coupled system of Caputo fractional differential equations of orders $\alpha, \beta\in(1,2]$, subject to two-point boundary conditions. The model incorporates nonlinear nonlocal integral terms that capture the memory-dependent interactions between thermal and electrical dynamics in thermistor materials. We rigorously establish existence via Schaefer’s fixed-point theorem and uniqueness through Banach’s contraction principle in a Banach space of continuous and continuously differentiable functions. Additionally, we analyze Ulam–Hyers stability to quantify solution sensitivity to initial perturbations. A numerical example highlights the effects of fractional orders and nonlocal feedback on system behavior. This work generalizes classical thermistor models and provides a …

A Scoping Review On Governing The Commercial Determinants Of Health: Mechanisms, Tools, And Collaborative Approaches, Alyssa S. Khan, Sierra Arnold, Imran Bari, Isabel G. Long, Nino Paichadze

Student Works

Purpose: The commercial determinants of health (CDoH) are the systems, practices, and pathways through which commercial actors drive health and equity. This review aimed to identify CDoH governance approaches, distinguishing between promoted and criticized approaches.

Design/Methodology/Approach: We conducted a systematic scoping review in PubMed and Google Scholar databases. Relevant grey literature was also identified through citation searching and reference list review. Our search strategy combined terms related to economic and commercial determinants of health, governance models, and health outcomes. English-language publications between January 2000 to December 2025 were included. Relevant data from included sources were extracted and then synthesized using …

Norris Burroughs, Mark Naison, Steven Payne

Oral Histories

No abstract provided.

Trends In Self-Reported Responses To Nutrition Facts Labels Before And After Nutrition Labeling Policy Implementation: A Comparison Of Adults In The United States And Mexico, Jim Thrasher Ph.D., Ma, Ms, Victor Vilalobos, Dai Fang, Alejandra Jáuregui, Alejandra Contreras-Manzano, Rachel Davis Ph.D., Lana Vanderlee, Christine M. White, Rachel B. Acton, James W. Hardin, Edward A. Frongillo Jr. Ph.D., Simón Barquera, David Hammond

Faculty Publications

Background

Objectives

Methods

Quality Improvement Project: Integrating Modified Early Warning Score (Mews) Criteria Into A Local Community College's Nursing Curriculum, Breanna C. Bell

Doctor of Nursing Practice Projects

There is an international priority for early recognition of patient deterioration with adequate responses to facilitate patient safety. The modified early warning score (MEWS) tool is commonly used to identify and respond to acute patient deterioration, so it is effective to educate nursing students on its use to influence their future practice. However, there is a lack of a curriculum to integrate MEWS criteria for associate degree in nursing (ADN) students at a local community college. This quality improvement project aimed to enhance ADN faculty’s self-efficacy and ability to integrate MEWS criteria into the didactic curriculum at a community college …

E. The Michael Hofmann Seismic Sections - Part B, Michael H. Hofmann

1980 Flathead Lake Seismic Survey

This book contains a set  Images of the full seismic sections that were generated by Michael Hofmann in the early 2000s.  Links to the images follow the narrative by Robert W. Lankston.  This set of images relates to those lines that are not labeled on the track map in Figure 4C of the Kogan (1981) thesis.

Rudolph Coombs, Mark Naison, Steven Payne

Oral Histories

Coombs went on to attend Payne College in Georgia through a basketball scholarship. During his time at Payne, he became president of the undergraduate chapter of Alpha Kappa Psi, where he fundraised. His time at Payne would be unfortunately cut short when he was wrongfully arrested for assault and robbery. This happened when he was leaving a jewelry store in the Bronx during one of his breaks from school.

This would effectively change the trajectory of Coombs’ life. He was tried three times, found guilty two times, but on the third time, he was declared innocent after the victim told …

Charity Simone, Mark Naison, Anthony Abd-Al Shafi Rosado

Oral Histories

Simone’s path to leadership was inspired by her late mentor, Charles Foster, who encouraged her to be an active voice in their community. After seeing issues with building maintenance and a lack of clear communication, Simone ran for office and was elected Treasurer of her Building Association in 2023. Through this role, she noticed that community work is complex and needs navigating different opinions, yet the experience ultimately reinforced her belief that community is a “verb.” To her, it is an intentional, ongoing action that requires showing up every day to hold the system accountable.

A significant aspect of Simone's …

Testing The Accuracy Of Commercial Wrist-Wearable Activity Trackers At Different Exercise Intensities, Jabeth Azpeitia Aranda, Murat Karabulut, Rebekah D. Schlatter, Guillermo Perez, Ulku Karabulut

International Journal of Exercise Science: Conference Proceedings

Consumer wrist-worn activity trackers are widely used to monitor physical activity and physiological responses during exercise, yet their accuracy across exercise intensities and physiological variables remains uncertain. PURPOSE: To evaluate the accuracy of wrist-wearable fitness trackers for heart rate (HR), oxygen saturation (SpO₂), energy expenditure (EE), and step count across exercise intensities. METHODS: Thirty (30) recreationally active adult males and females (n = 30; age = 22.8 ± 4.5 yr) completed four sessions consisting of informed consent, anthropometric and baseline measurements, and three treadmill exercise sessions. Exercise sessions included walking at 3 mph (0% incline), walking at 3 mph (12% …

Pre- To Post-Season Changes In Body Composition Among Division Iii Football Players, Sebastian Schaefer, Cesar Navarro, Edward Merritt

International Journal of Exercise Science: Conference Proceedings

Collegiate football player body composition likely changes over the course of the season, and might differ based on player position. The extent to which this occurs in Division III football players is not known. PURPOSE: To examine differences in body composition from pre- to post-season and positional differences among Division III football players at Southwestern University. METHODS: Division III NCAA football players at Southwestern University were recruited prior to the 2025 season. Body composition was determined pre- and post-season by dual energy x-ray absorptiometry (DEXA).  Only athletes who completed the season and were not sidelined due to injury …

Physical Fitness Readiness And Preparation For Law Enforcement Academy A Pilot Cohort Study, Logan Moore, Sharon Carano, Karen Wallace, Pamela Rast

International Journal of Exercise Science: Conference Proceedings

It has been shown that lower baseline physical fitness among first responder recruits, specifically law enforcement, is consistently associated with (1) higher rates of academy attrition (including failures to meet physical standards or to complete training) and (2) increased injury risk during academy training PURPOSE: The purpose of this study is to test the physical fitness readiness of college students for entry into a law enforcement academy, and prepare the students for the rigors of the police officer physical resilience assessment, and the future physical activity requirements of being in law enforcement.  METHODS: College students (20±1.47 years old) …

A Novel Method For Producing Muscle Cramps Without Electrical Stimulation, Elizabeth C. Krajca, Benjamin Greengold, Edward Merritt

International Journal of Exercise Science: Conference Proceedings

Muscle cramps are involuntary, often painful, skeletal muscle contractions that can occur for multiple reasons including physical exertion, injury, dehydration, nutritional deficiencies, or other neuromuscular conditions. Understanding muscle cramping etiology and treatments is difficult due to their often unpredictable timing and conditions that need to be met for many individuals to experience them. Previous studies have induced muscle cramping through electrical stimulation, long duration exercise, dehydration, and other methods, but these techniques are either non-physiological or complex and time attentive. PURPOSE: Therefore, we aimed to develop a new method to produce a muscle cramp in the biceps brachii in a …

Accelerated Recovery Following High-Dose Platelet-Rich Plasma Injection For Distal Biceps Tendon Tear In A Weightlifter, Saahil Naik, Stephanie Ward, John Broussard

International Journal of Exercise Science: Conference Proceedings

CASE HISTORY: A 44-year-old male avid weightlifter presented to the clinic for evaluation of acute onset distal bicep pain following a weightlifting session. He reports feeling a pop in his right distal bicep while performing a preacher curl and subsequently dropping the weight. PHYSICAL EXAM: Examination of the right arm demonstrated guarding with the elbow held in slight flexion without obvious deformity. Ecchymosis was noted on the volar aspect of the proximal forearm. Tenderness to palpation was present along the distal bicep tendon, as was elicitation of pain and weakness with resisted elbow flexion and supination. DIFFERENTIAL DIAGNOSES …

Footwear Matters: Speed And Barefoot Running Enhance Medial Gastrocnemius Emg, Kaleb M. Luna, Bryon C. Applequist

International Journal of Exercise Science: Conference Proceedings

Barefoot running alters foot strike mechanics and may change lower-extremity muscle demands compared to shod running, particularly at different speeds. PURPOSE: The purpose of this study was to examine the effects of footwear (barefoot vs. shod) and running speed (preferred vs. +20%) on normalized electromyographic (EMG) amplitude of the medial gastrocnemius (MG) and tibialis anterior (TA) in recreational runners. METHODS: Five healthy recreational runners completed treadmill running trials at preferred speed and +20% preferred speed in barefoot and shod conditions. Bilateral surface EMG was recorded from MG and TA (1500 Hz). Signals were bandpass filtered (20–450 Hz), rectified, …

A Comparative Analysis Of Maladaptive Perfectionism In Male And Female Competitive Bodybuilders, Maddox B. Utter, Christian O. Quintero, Samantha S. Dardaman, Stephen E. Rowden, Scott B. Martin

International Journal of Exercise Science: Conference Proceedings

Bodybuilding is a sport focused on physique optimization, where success is determined by judges’ evaluations of muscle mass, symmetry, and definition. Due to the sport’s emphasis of physical aesthetics, bodybuilders may feel the need to compare themselves with other competitors. This evaluation and comparison of physique may expose athletes to maladaptive perfectionistic tendencies, such as setting unattainably high standards, excessive worry over mistakes, and a diminished sense of competence. While current bodybuilding literature is limited, previous research suggests that perfectionism may lead to psychological impairments (e.g., body dysmorphia, anxiety, and reduced self-confidence) which may manifest differently between male and female …

Unusual Presentation Of An Anterior Talus And Fibular Head In A Youth Soccer Player, Stephanie Ward, Saahil Naik, Rajinder Persaud

International Journal of Exercise Science: Conference Proceedings

CASE HISTORY: The patient is a 13-year-old male who presented to the osteopathic manipulative medicine (OMM) clinic for evaluation of left ankle pain and stiffness. He reported ankle soreness, which he believed is due to extensive participation in soccer and running 2-3 miles daily. He occasionally experiences stiffness in his left knee and left ankle during physical activity, which does not prevent him from participating in athletic activities. He is left lower extremity dominant. He has a history of a grade 1 ankle sprain 2 years prior that was resolved with conservative management. He denied any other instances of …

How Does The Stage Of Pregnancy Influence Gait And Sway In Pregnant Women From Six To Eight Months., Lilie-Rose S. Gilbert, Scott P. Mclean, Edward Merritt

International Journal of Exercise Science: Conference Proceedings

Physiological changes that affect gait, posture, and balance during the late stages of pregnancy increase the risk of falling.  These changes were examined across the stages of pregnancy using simulated pregnancy loading. PURPOSE: To compare gait and postural balance measures under three loading conditions simulating zero, 6, and 8-months of simulated pregnancy. We predicted that the added weight in late-stage pregnancy would adversely affect gait characteristics and reduce postural control. METHODS: Twenty-one healthy females (20.1±1.2 years, 1.79±0.11 m, 64.1±9.5 kg) completed a 10-m walking gait assessment.  They then completed three trials under each condition, including the Stability Evaluation Test (SET) …