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Experimental Investigation Of Exhaust Temperature Effect On Teg Cells Power Generation And Assessment Of Engine Sfc And Emissions, Eid Mohamed Mar 2026

Experimental Investigation Of Exhaust Temperature Effect On Teg Cells Power Generation And Assessment Of Engine Sfc And Emissions, Eid Mohamed

Engineering and Technology Journal

The thermoelectric cell generators (TECG) convert thermal power into electrical power generated. The main factor in its operation is the temperature difference (TD) between its surfaces. An experimental investigation was conducted into the waste heat recovery performance of the TECG system. Forty thermoelectric cells (TECs) are supported on the (4 5) upper and (4 5) lower and upper arrangement of the engine exhaust manifold. The electrical power generated (EPG), exhaust gas flow rate, exhaust temperature, brake-specific fuel consumption (BSFC), and exhaust emissions were experimentally investigated under different engine speeds and 50 N.m and 100 N.m engine load conditions. Comparative results …


Recent Advances In Journal Bearings: Wear Fault Diagnostics, Condition Monitoring And Fault Diagnosis Methodologies, Nazik Jebur, Wafa Soud Mar 2026

Recent Advances In Journal Bearings: Wear Fault Diagnostics, Condition Monitoring And Fault Diagnosis Methodologies, Nazik Jebur, Wafa Soud

Engineering and Technology Journal

This review comprehensively encompasses a range of recent studies on journal bearings, emphasizing wear fault diagnostics, condition monitoring, and fault diagnosis methodologies. A significant finding reveals a shift back to the utilization of journal bearings in various rotating machinery such as compressors, motors, turbines, and pumps. Various methodologies employed in these recent studies include vibration analysis, machine learning, deep learning, and both numerical and experimental simulations. Key findings indicate that ensemble models, such as the CNN and deep neural network (CNNEPDNN) model, significantly improve convergence speed, test accuracy, and F-Score in bearing fault diagnosis by 15-20% compared to individual models. …


Finite Element Analysis And Artificial Neural Network For Stress Distribution Of An Aircraft Model In A Wind Tunnel, Ahmed Al-Mulla Khalaf, Sinan Al-Haddad, Bilal Al-Oubaidi, Naseem Ibrahim, Fawaz Abdulwahed, Athraa Hilal Mar 2026

Finite Element Analysis And Artificial Neural Network For Stress Distribution Of An Aircraft Model In A Wind Tunnel, Ahmed Al-Mulla Khalaf, Sinan Al-Haddad, Bilal Al-Oubaidi, Naseem Ibrahim, Fawaz Abdulwahed, Athraa Hilal

Engineering and Technology Journal

Wind tunnels are instrumental in the aerodynamic analysis of aircraft model structures, enabling the replication of real circumstances for better design and performance evaluation. This paper presents a novel enhancement to stress distribution predictions in wind tunnel simulations by combining Finite Element Analysis (FEA) and Artificial Neural Networks (ANN). First, the research focuses on analyzing ANSYS Fluent data, which provides insights into the complex fluid dynamics inside the wind tunnel. The proposed approach combines the best available FEA and ANN techniques regarding prediction accuracy and computational efficiency. Such findings are those that evidence that predictions of real stress levels using …


The Physical World Of The Greeks, Samuel Sambursky Mar 2026

The Physical World Of The Greeks, Samuel Sambursky

Hannah Arendt Marginalia - All

London : Routledge and Paul, 1956.

Call#: Q127.G7 S313 1956

Contains underlining and marginalia

PDF information: 17 pages - 5.7MB


Between Peaks And Traditions: Indigenous Andean Women Mountaineers, Hybrid Identities, And Decolonial Resistance Through Sport, Ilina Arsova, Lars Dzikus Mar 2026

Between Peaks And Traditions: Indigenous Andean Women Mountaineers, Hybrid Identities, And Decolonial Resistance Through Sport, Ilina Arsova, Lars Dzikus

Journal of Global South Sport Studies

This paper explores the hybrid identities of Indigenous Bolivian women mountaineers, focusing on how they embrace and resist elements of both Indigenous and Western traditions through sports. Challenging dominant Western narratives of mountaineering (Rak, 2021), these women engage in climbing as an act of cultural preservation (Haynes, 2013; Rak, 2021) and gender advocacy (U.N. Women, 2021). Informed by Indigenous feminism (Caravajal, 2019; Green, 2020) and social identity theory (Tajfel & Turner, 1979), the study explores the intersections of gender, culture, and mountain sports in the South American Andes. Through an interpretivist lens, this study uses narrative inquiry (Clandinin & Connelly, …


Performance Evaluation Of Self-Compacting Geopolymer Concrete With Recycled Brick Aggregate Under Varied Curing And Temperature Conditions, Thavasumony Dhasan, Raid S. Alrashidi, Muhammad Saleem, Joonaith C. Veedu, Shahnawaz Alam Mar 2026

Performance Evaluation Of Self-Compacting Geopolymer Concrete With Recycled Brick Aggregate Under Varied Curing And Temperature Conditions, Thavasumony Dhasan, Raid S. Alrashidi, Muhammad Saleem, Joonaith C. Veedu, Shahnawaz Alam

Yanbu Journal of Engineering and Science

In recent days, Self-Compacting Geopolymer Concrete (SCGC) has the potential to revolutionize concrete technology by combining the benefits of both Geopolymer Concrete (GPC) and Self-Compacting Concrete (SCC). The production of SCGC requires proper selection of materials and proportions to achieve a composite concrete with a refined pore structure and low permeability. Additionally, chemical and mineral admixtures play a crucial role in enhancing and refining the pore structure of SCGC, as mineral admixtures reduce the absorbency of the cement matrix further and improve the porosity of the aggregates. In this investigation, the impact of high temperatures on the properties of SCGC …


Evaluating The Interpolation Techniques For Completing The Soil Data And Mapping Jazan City, Saudi Arabia, Using Gis, Ehab Sabi, Mahmoud Abdelrahim Abdelgiom Mar 2026

Evaluating The Interpolation Techniques For Completing The Soil Data And Mapping Jazan City, Saudi Arabia, Using Gis, Ehab Sabi, Mahmoud Abdelrahim Abdelgiom

Yanbu Journal of Engineering and Science

The goal of the study is to determine which of the chosen interpolation techniques is optimal for forecasting soil characteristics in unmeasured areas for infrastructure and building projects. The study also incorporates geotechnical data from 23 regional boreholes with the UNESCO soil classification system developed by the Food and Agriculture Organization (FAO). The mapping and accuracy of different interpolation techniques were assessed using ArcGIS 10.4. Additionally, Spline, Inverse Distance Weighting (IDW), Kriging, Natural Neighbor, and Radial Basis Functions are used to assess the precision and efficacy of several interpolation techniques. The investigation's conclusions showed that the ``natural neighbor'' strategy was …


Bot-Theology: Inviting, Prosperous, And (In)Authentic Community, Daniel Jesse Mar 2026

Bot-Theology: Inviting, Prosperous, And (In)Authentic Community, Daniel Jesse

University Faculty Publications and Creative Works

The paper analyzes the theology, emotions, and community formation of the bots who post on YouTube and the people who respond to them. The paper finds that the bots’ theology is evangelical, charismatic, and prosperity-oriented. The paper also finds that the people who respond to the bots are sincere, supportive, and expressive, and that they create a virtual community of faith that is joyful, hopeful, and trusting. The paper suggests that virtual gatherings of Christians need more scholarly attention and that more research is needed on the emotional formation and theological implications of these online interactions.


Section Iii -- College Of Liberal Arts Policies And Procedures (Updated 03/02/2026), All Faculty Mar 2026

Section Iii -- College Of Liberal Arts Policies And Procedures (Updated 03/02/2026), All Faculty

Faculty Handbooks

No abstract provided.


Selassie Atoklo V. Attorney General United States Of America Mar 2026

Selassie Atoklo V. Attorney General United States Of America

2026 Decisions

Agency


Spectroscopy And Photochemistry Of The Astrochemical Molecules Sicp And Alcp, Vincent J. Esposito, Tarek Trabelsi, Rebecca Firth, Ryan C. Fortenberry, Joseph S. Francisco Mar 2026

Spectroscopy And Photochemistry Of The Astrochemical Molecules Sicp And Alcp, Vincent J. Esposito, Tarek Trabelsi, Rebecca Firth, Ryan C. Fortenberry, Joseph S. Francisco

Biology, Chemistry, and Environmental Sciences Faculty Articles and Research

Through characterization of the electronic excited-state topology, linear-SiCP is predicted to be photostable in the UV region, whereas linear-AlCP is predicted to undergo photodissociation to form Al+CP products after absorption of light in the 200–250 nm range, representing a catalytic process for freeing aluminum molecules from a solid dust grain. Both SiCP and AlCP are predicted to have electronic transitions with large absorption cross sections (∼10–17 cm2) and to undergo fluorescence from bound excited states. The total electronic absorption spectrum is provided to inform electronic spectroscopy experiments. Silicon (SiC) and aluminum (Al2O3) dust …


Unapologetically Her: Leadership Lessons From Mom, Seth D. Kastle Ed.D., Courtney Imhoff Mar 2026

Unapologetically Her: Leadership Lessons From Mom, Seth D. Kastle Ed.D., Courtney Imhoff

Leadership Faculty Publications

The narrative of this article is a culmination of two lived experiences of the children of Melanie Elliott: Seth Kastle and Courtney Imhoff. Our mother has been the foundational influence on who we are and has been the catalyst in our development of a bias for action, a willingness to lead and a drive to take care of others. Through the process of writing, it became evident that, rather than conflating the overall narrative of this article into one voice, the stories were better told when preserved in their individual narratives. The reader will note that above each paragraph is …


Workforce Participation In Northeast Kentucky: A Qualitative Documentary Study, Timothy A. Gibbs Mar 2026

Workforce Participation In Northeast Kentucky: A Qualitative Documentary Study, Timothy A. Gibbs

Morehead State Theses and Dissertations

A capstone submitted in partial fulfillment of the requirements for the degree of Doctor of Education in the Ernst and Sara Lane Volgenau College of Education at Morehead State University By Timothy A. Gibbs on March 2, 2026.


R. S. V. East Brunswick Township School District Mar 2026

R. S. V. East Brunswick Township School District

2026 Decisions

USDC for the District of New Jersey


Jax Animal Behavior System (Jabs), A Genetics-Informed, End-To-End Advanced Behavioral Phenotyping Platform For The Laboratory Mouse., Anshul Choudhary, Brian Q Geuther, Thomas J. Sproule, Glen L Beane, Vivek Kohar, Jarek Trapszo, Vivek Kumar Mar 2026

Jax Animal Behavior System (Jabs), A Genetics-Informed, End-To-End Advanced Behavioral Phenotyping Platform For The Laboratory Mouse., Anshul Choudhary, Brian Q Geuther, Thomas J. Sproule, Glen L Beane, Vivek Kohar, Jarek Trapszo, Vivek Kumar

Faculty Research 2026

Automated detection of complex animal behavior remains a challenge in neuroscience. Developments in computer vision have greatly advanced automated behavior detection and allow high-throughput preclinical and mechanistic studies. An integrated hardware and software solution is necessary to facilitate the adoption of these advances in the field of behavioral neurogenetics, particularly for non-computational laboratories. We have published a series of papers using an open field arena to annotate complex behaviors such as grooming, posture, and gait as well as higher-level constructs such as biological age and pain. Here, we present our integrated rodent phenotyping platform, JAX Animal Behavior System (JABS), to …


Jax Animal Behavior System (Jabs), A Genetics-Informed, End-To-End Advanced Behavioral Phenotyping Platform For The Laboratory Mouse., Anshul Choudhary, Brian Q Geuther, Thomas J. Sproule, Glen L Beane, Vivek Kohar, Jarek Trapszo, Vivek Kumar Mar 2026

Jax Animal Behavior System (Jabs), A Genetics-Informed, End-To-End Advanced Behavioral Phenotyping Platform For The Laboratory Mouse., Anshul Choudhary, Brian Q Geuther, Thomas J. Sproule, Glen L Beane, Vivek Kohar, Jarek Trapszo, Vivek Kumar

Faculty Research 2026

Automated detection of complex animal behavior remains a challenge in neuroscience. Developments in computer vision have greatly advanced automated behavior detection and allow high-throughput preclinical and mechanistic studies. An integrated hardware and software solution is necessary to facilitate the adoption of these advances in the field of behavioral neurogenetics, particularly for non-computational laboratories. We have published a series of papers using an open field arena to annotate complex behaviors such as grooming, posture, and gait as well as higher-level constructs such as biological age and pain. Here, we present our integrated rodent phenotyping platform, JAX Animal Behavior System (JABS), to …


Graduate Council Minutes 2026-03-02, Northern Illinois University Mar 2026

Graduate Council Minutes 2026-03-02, Northern Illinois University

Graduate Council Archives

No abstract provided.


Comment On The Draft Environmental Impact Statement For New Operations For Lake Powell And Lake Mead Post-2026, Bryan Williams, Caitlyn Andrus, Brittany Fager, Matthew Fugal, Parker Hansen, Ashley Jones, Shaun Joseph, Ashley Mcallister, Braden Wilding, David Rosenberg Mar 2026

Comment On The Draft Environmental Impact Statement For New Operations For Lake Powell And Lake Mead Post-2026, Bryan Williams, Caitlyn Andrus, Brittany Fager, Matthew Fugal, Parker Hansen, Ashley Jones, Shaun Joseph, Ashley Mcallister, Braden Wilding, David Rosenberg

Civil and Environmental Engineering Student Research

We appreciate the Bureau of Reclamation’s extensive effort in preparing the Post-2026 Draft Environmental Impact Statement (Draft EIS) for operational guidelines for Lake Powell, Lake Mead, and the Colorado River Basin. This commentary will address positives, questions, and concerns from the Draft EIS. We also share recommendations for consideration in the Final EIS.


Rising Sun: The Musical Legacy Of Clarence "Tom" Ashley, The Reece Museum, East Tennessee State University Mar 2026

Rising Sun: The Musical Legacy Of Clarence "Tom" Ashley, The Reece Museum, East Tennessee State University

The Reece Museum Exhibition Publications

Clarence “Tom” Ashley (September 29, 1895 - June 2, 1967) was a musician from Mountain City, Tennessee. Ashley began making music at medicine shows and local fiddlers’ conventions as early as 1911. Notably, Ashley participated in the Mountain City Fiddlers Convention in May 1925, an event that is considered to have helped launch the modern country music industry by catching the attention of recording executives in the years leading up to the historic Bristol Sessions (1927-1928) and Johnson City Sessions (1928-1929). Ashley was recorded during the historic 1929 Johnson City Sessions as both a solo artist and as a member …


Political Mediatization In The Digital Era: The Case Of Walhi West Sumatera’S Environmental Advocacy, Muhammad Thaufan Arifuddin, Ernita Arif, Yuliandre Darwis, Rinaldi Rinaldi, Muhammad Al-Amin Dalmenda Mar 2026

Political Mediatization In The Digital Era: The Case Of Walhi West Sumatera’S Environmental Advocacy, Muhammad Thaufan Arifuddin, Ernita Arif, Yuliandre Darwis, Rinaldi Rinaldi, Muhammad Al-Amin Dalmenda

JURNAL KOMUNIKASI INDONESIA

This article examines how political mediatization operates at the local level through environmental civil society activism in post-authoritarian Indonesia. Focusing on the West Sumatra chapter of the Indonesia Forum for Environment (WALHI) as a critical case, the study argues that media logic is not merely imposed by political elites or mainstream media, but is strategically appropriated by local civil society organizations to contest oligarchic power, shape public agendas, and sustain democratic engagement at the subnational level. Using a qualitative case study approach, data were collected through participant observation, in-depth interviews with environmental activists and youth organizers, and an analysis of …


Faculty Senate Agenda March 2, 2026, Utah State University Mar 2026

Faculty Senate Agenda March 2, 2026, Utah State University

Faculty Senate & Faculty Senate Executive Committee

  • 3:00 Call to Order
  • Approval of Minutes February 2, 2026
  • 3:05 University Business
  • 3:20 Faculty Senate Business
  • 3:35 Report
  • Parking and Transportation
  • 3:40 Information
  • EPC Report - February 5, 2026
  • 4:00 Old Business
  • 4:05 New Business
  • Special Faculty Forum
  • Adjourn: 4:30 pm


Should Single-Sales-Factor Formulas Be Constitutional?, Reuven S. Avi-Yonah Mar 2026

Should Single-Sales-Factor Formulas Be Constitutional?, Reuven S. Avi-Yonah

Articles

On October 28, 2025, Florida sued California in the Supreme Court over its application of a single-sales-factor (SSF) formula to exclude large out-of-state asset sales. But Florida couched its critique in much broader terms, seemingly attacking the validity of the SSF altogether. Florida Attorney General James Uthmeier (R) stated that: California has created a tax system that punishes economic freedom. We will not tolerate California over-taxing revenue earned in Florida. The Newsom regime is obviously attempting to punish business owners who have fled California due to its disastrous policies. Given that multitudes of California businesses and residents are moving to …


Shiga Toxin-Producing Escherichia Coli Outbreak In Canadian Daycare Centers, Mohamed Eltorki, Oluwatimilehin O Ajayi, Jina Seok, Jianling Xie, Francesco A Rizzuti, Byron M Berenger, Phillip I Tarr, Andrew T Pavia, Kate Snedeker, Silviu Grisaru, Otto G Vanderkooi, Linda Chui, Gillian A M Tarr, Gemma Vomiero, Stephen B Freedman Mar 2026

Shiga Toxin-Producing Escherichia Coli Outbreak In Canadian Daycare Centers, Mohamed Eltorki, Oluwatimilehin O Ajayi, Jina Seok, Jianling Xie, Francesco A Rizzuti, Byron M Berenger, Phillip I Tarr, Andrew T Pavia, Kate Snedeker, Silviu Grisaru, Otto G Vanderkooi, Linda Chui, Gillian A M Tarr, Gemma Vomiero, Stephen B Freedman

2020-Current year OA Pubs

IMPORTANCE: Shiga toxin-producing Escherichia coli (STEC) infections have significant morbidity, with 15% to 20% of children developing hemolytic uremic syndrome (HUS), more than half of whom require kidney replacement therapy (KRT).

OBJECTIVE: To describe health care resource utilization, clinical outcomes, and outcomes associated with daily laboratory monitoring for thrombotic microangiopathy (TMA) in a large point-source STEC outbreak.

DESIGN, SETTING, AND PARTICIPANTS: This retrospective cohort study was conducted among a population-based cohort of individuals exposed to a contaminated food item served in 11 childcare centers in Calgary, Alberta, Canada, on August 29, 2023. Children and adults with confirmed STEC infection linked …


Trends In Mammography Use Among Women Aged 40 To 74 Years In The Us, 2002-2022, Syed Mahfuz Al Hasan, Debbie L Bennett, Adetunji T Toriola Mar 2026

Trends In Mammography Use Among Women Aged 40 To 74 Years In The Us, 2002-2022, Syed Mahfuz Al Hasan, Debbie L Bennett, Adetunji T Toriola

2020-Current year OA Pubs

IMPORTANCE: Understanding how prior policies, systemic factors, and public health events have shaped mammography use among US women is essential for interpreting the 2024 US Preventive Services Task Force (USPSTF) recommendation update and identifying gaps to inform equitable public health strategies.

OBJECTIVE: To analyze mammography use trends in US women aged 40 to 49 and 50 to 74 years from 2002 to 2022 and assess variation by sociodemographic, health care access, behavioral, and geographic factors, including associations with the 2009 USPSTF recommendation and the COVID-19 pandemic.

DESIGN, SETTING, AND PARTICIPANTS: This cross-sectional study used data from the Behavioral Risk Factor …


Media Reporting Of The 2024 Us Preventive Services Task Force Mammography Guideline Update, Tamar Parmet, Yue Li, Joseph Cappella, Laura D Scherer, Erika A Waters, Ashley J Housten Mar 2026

Media Reporting Of The 2024 Us Preventive Services Task Force Mammography Guideline Update, Tamar Parmet, Yue Li, Joseph Cappella, Laura D Scherer, Erika A Waters, Ashley J Housten

2020-Current year OA Pubs

No abstract provided.


Body Mass Index Is Associated With Direction-Specific Increases In With-The-Rule Corneal And Refractive Astigmatism In Schoolchildren, Eoin Kerin, Michael Moore, James Loughman, Siofra Harrington Mar 2026

Body Mass Index Is Associated With Direction-Specific Increases In With-The-Rule Corneal And Refractive Astigmatism In Schoolchildren, Eoin Kerin, Michael Moore, James Loughman, Siofra Harrington

Research Outputs: 2025-Present

PurposeExamine the association between body mass index (BMI) and astigmatism directionality using vector analysis of refractive and corneal components (J0, J45) in a nationally representative sample of schoolchildren. Refractive and corneal J0 was the primary outcome, with secondary aims to assess whether BMI influences astigmatism severity or other refractive and axial parameters.MethodsThis cross-sectional study recruited 1626 schoolchildren aged 6–7 (n = 728) and 12–13 years (n = 898) from 37 randomly selected schools in Ireland. Cycloplegic autorefraction and ocular biometry were obtained. Height and weight were measured and BMI calculated and analysed as a continuous predictor, with WHO-defined BMI categories …


Design And Evaluation Of A Collaborative Xr Framework With Abstract Building Blocks For Manufacturing System Prototyping, Shaun Macdonald, Bixun Chen, Yuanjie Xia, Rami Ghannam Mar 2026

Design And Evaluation Of A Collaborative Xr Framework With Abstract Building Blocks For Manufacturing System Prototyping, Shaun Macdonald, Bixun Chen, Yuanjie Xia, Rami Ghannam

School of Engineering Technology Faculty Publications

Manufacturing systems are complex installations designed and developed by stakeholders with differing expertise. However, system design primarily features traditional methods, long lead times, and siloed environments, which obstruct comprehension, communication, or collaboration. Prior research has used extended reality (XR) to prototype and visualise specific manufacturing applications; however, flexible system modelling remains complex. To address these issues and lay the foundation for future-facing manufacturing design as part of Industry 4.0, we introduce ARTIFY—a prototype XR framework for conceptual system prototyping. It features abstract building blocks that can be semantically reconfigured to support early-stage modelling of varied manufacturing systems in immersive environments. …


Do Attorneys Discriminate? Understanding The Implications Of Bias On Voir Dire & Jury Selection, Jessica Lambert Mar 2026

Do Attorneys Discriminate? Understanding The Implications Of Bias On Voir Dire & Jury Selection, Jessica Lambert

Doctor of Psychology (PsyD)

Biases, generally defined as predispositions or inclinations for or against ideas, is a broadly prevalent aspect of human cognition and decision-making (Steinhauser, 2020). Bias is present in every decision-making structure, even those in which we strive for the greatest neutrality, such as the legal system (Alter, 2010). An especially important place to seek to minimize or eliminate bias is in the courtroom. Our justice system is built upon the assumption of impartiality and nonpartisanship (Rosenberg, 2008), yet biases and stereotypical decision- making are common criticisms of the court (Curley et al., 2022; Chopp, 2017). This study attempts to identify the …


Transforming Orthopedic Clinic Workplace Culture Using The Pdsa Cycle, Tania Mae Golo-Atkin, Jodie Mae B. Shiba, Daniel A. Collins, Chrystal Leigh Lewis Mar 2026

Transforming Orthopedic Clinic Workplace Culture Using The Pdsa Cycle, Tania Mae Golo-Atkin, Jodie Mae B. Shiba, Daniel A. Collins, Chrystal Leigh Lewis

Creating Healthy Work Environments (CHWE)

BACKGROUND: Prior to the COVID-19 pandemic, the work environment was already associated as a contributing factor to nurses’ intention to leave the workplace (Nantsupawat et al., 2016; Shah et al. 2021). Additionally, peer-to-peer nursing isolation is a problem within ambulatory nursing (Allen, 2016). However, specific investigation into intent to leave in ambulatory nursing is limited. The National Database of Nursing Quality Indicators (NDNQI) survey was first used in this setting’s ambulatory clinics in 2021. The Orthopedic Clinic RN Coordinators (RNC) initial 2021 NDNQI scores on the specific metric exploring nurses’ intentions to leave their current workplace within 3 years was …


Designing Novel Bisquinoline Antimalarials From Historical 4-Aminoquinolines To Combat Drug-Resistant Malaria, Mason J. Handford, Yuexin Li, Terry Riscoe, Xiaowei Zhang, Jane X. Kelly, Michael K. Riscoe Mar 2026

Designing Novel Bisquinoline Antimalarials From Historical 4-Aminoquinolines To Combat Drug-Resistant Malaria, Mason J. Handford, Yuexin Li, Terry Riscoe, Xiaowei Zhang, Jane X. Kelly, Michael K. Riscoe

Chemistry Faculty Publications and Presentations

Plasmodium falciparum, the deadliest causative agent of malaria, continues to evade eradication efforts through widespread drug resistance. The recent development of ADC-028, a 4-aminoquinoline antimalarial with excellent activity and pharmacokinetic properties, prompted the investigation of bisquinoline analogs featuring similar structural motifs. Here, we describe a structure-activity relationship study that guided the optimization of compounds with key features, including the 4-anilinoquinoline core and diverse bridging linkers. Several analogs exhibited potent in vitro activity (IC50 < 20 nM) against both drug-sensitive and multidrug-resistant P. falciparum strains, while maintaining favorable cytotoxicity profiles. Among them, 25 demonstrated improved intrinsic metabolic stability (t1/2 = 121 min) and potent in vivo efficacy (ED50 = 0.32 mg/kg/day), achieving complete curative protection at a reduced dose compared to ADC-028. While 25 showed moderately reduced oral bioavailability (F = 43%) and a shorter half-life (T1/2 = 27.2 h) relative to ADC-028, its enhanced in vivo efficacy underscores its therapeutic potential. This work highlights a promising path forward in developing antimalarials that retain the efficacy of legacy compounds while overcoming modern resistance mechanisms.