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Articles 29671 - 29700 of 1821584
Full-Text Articles in Entire DC Network
How Can Learning Management Systems Positively Impact Student Engagement In Online Courses?, Jerald P. Wilson
How Can Learning Management Systems Positively Impact Student Engagement In Online Courses?, Jerald P. Wilson
Electronic Theses and Dissertations
The topic of this dissertation is learning management systems, specifically Canvas. Research has proven that student engagement is a strong factor in student achievement in both online and inperson courses. The COVID-19 pandemic highlighted a deficit in instructors’ ability to acquire and maintain student engagement in online courses. This study details why this problem exists and how instructors have successfully addressed it in higher-level online courses. The primary purpose of this qualitative descriptive study was to examine how learning management systems, specifically Canvas, can increase student engagement in online courses in higher education. Qualitative research was the chosen paradigm for …
Discovery Of A New Cataclysmic Variable, Galex J211240.9–422959, Via The Exoasteroids Citizen Science Project, Mei Lin, Aaron Meisner, Siyi Xu, Arttu Sainio, Liliana E. Rivera Sandoval, Paula Szkody, Christopher Tanner, Laura K. Rogers, Sarah Casewell, Austin Humphreys
Discovery Of A New Cataclysmic Variable, Galex J211240.9–422959, Via The Exoasteroids Citizen Science Project, Mei Lin, Aaron Meisner, Siyi Xu, Arttu Sainio, Liliana E. Rivera Sandoval, Paula Szkody, Christopher Tanner, Laura K. Rogers, Sarah Casewell, Austin Humphreys
Physics & Astronomy Faculty Publications
We report the discovery and spectroscopic classification of a new cataclysmic variable (CV), GALEX J211240.9–422959 (Gaia DR3 source ID 6580244356829724928). This object was initially identified as a source exhibiting strong mid-infrared variability in Wide-field Infrared Survey Explorer (WISE) time-series data by a volunteer participating in the Exoasteroids citizen science project. Prompted by this strong variability at 3–5 μm, we obtained a follow-up optical spectrum using the Gemini Multi-Object Spectrograph at the Gemini South Observatory. The resulting spectrum displays a blue continuum dominated by strong, broad emission lines of the hydrogen Balmer series and neutral helium, spectral signatures characteristic of …
Antimicrobial Performance Of Amorphous Vs. Crystalline La1-Xsrxcoo3 Perovskites, S. M. Au Shohag, Fahmida Akhter, Ahmed Touhami, Swati Mohan, Md. Wasikur Rahman, Mohammed Jasim Uddin
Antimicrobial Performance Of Amorphous Vs. Crystalline La1-Xsrxcoo3 Perovskites, S. M. Au Shohag, Fahmida Akhter, Ahmed Touhami, Swati Mohan, Md. Wasikur Rahman, Mohammed Jasim Uddin
Physics & Astronomy Faculty Publications
Perovskite materials, with their unique crystal structure and chemical properties, are emerging as promising antimicrobial agents for potential biomedical applications. In this research, different weight percentages of Sr2 + doped amorphous and crystalline Lanthanum Cobaltite (La1-xSrxCoO3 defined as LSCO) (x = 0, 0.025, 0.05, 0.1, and 0.15) perovskite was synthesized by using a simple combination of sol-gel and molten-salt processes and characterized by X-ray diffraction (XRD), and scanning electron microscopy (SEM) ensures the uniform morphology of the materials. During antimicrobial study using the Kirby Bauer method, amorphous LSCO showed much better activity than crystalline LSCO against Escherichia coli, Vibrio …
A Search For Magnetically Active Binary Counterparts To Chandra X-Ray Sources In 47 Tucanae With Hst Imaging, Haldan N. Cohn, Phyllis M. Lugger, Craig O. Heinke, Maureen Van Den Berg, Liliana Rivera Sandoval, Jay Anderson
A Search For Magnetically Active Binary Counterparts To Chandra X-Ray Sources In 47 Tucanae With Hst Imaging, Haldan N. Cohn, Phyllis M. Lugger, Craig O. Heinke, Maureen Van Den Berg, Liliana Rivera Sandoval, Jay Anderson
Physics & Astronomy Faculty Publications
Using Hubble Space Telescope (HST) imaging, we searched for candidate magnetically active binary (AB) counterparts to low-luminosity Chandra X-ray sources in the globular cluster 47 Tucanae (NGC 104). We consider the catalog of 300 Chandra sources within the half-light radius of 47 Tuc compiled by C. O. Heinke et al. (2005). The 10-band HST imaging used to identify these sources spans the range from 275–658 nm. We generated a cross-matched catalog of objects detected by photometric reductions. We used this catalog to search for counterparts within Chandra source error circles using color–magnitude diagrams and a color–color plot. We …
Predictors Of Total Hip Arthroplasty Among Patients With Chronic Comorbidities: A Multivariate Analysis Of A Medically Underserved Region, Blake C. Martin, Manoj Peiris
Predictors Of Total Hip Arthroplasty Among Patients With Chronic Comorbidities: A Multivariate Analysis Of A Medically Underserved Region, Blake C. Martin, Manoj Peiris
School of Medicine Publications
Background
THA is a common orthopedic procedure that is expected to increase in the coming years. Obesity and osteoarthritis are major factors that increase the risk of individuals requiring THA. The Rio Grande Valley (RGV) is a distinctive health professional shortage area with high rates of obesity, arthritis, and diabetes. This study aims to examine the relationship between chronic medical conditions and the need for THA in this at-risk, medically underserved population.
Methods
This investigation employed a retrospective chart review encompassing patient records from January 1, 2018, through January 1, 2025, using the University of Texas Rio Grande Valley electronic …
Kidney Disease And Heart Failure: Recent Advances And Current Challenges: Conclusions From A Kidney Disease: Improving Global Outcomes (Kdigo) Controversies Conference, Carolyn S P Lam, Biykem Bozkurt, David Z I Cherney, Justin A Ezekowitz, Meg J Jardine, Sadiya S Khan, Magdalena Madero, Mark J Sarnak, Jozine M Ter Maaten, Michael Cheung, Jennifer M King, Morgan E Grams, Michel Jadoul, Nisha Bansal
Kidney Disease And Heart Failure: Recent Advances And Current Challenges: Conclusions From A Kidney Disease: Improving Global Outcomes (Kdigo) Controversies Conference, Carolyn S P Lam, Biykem Bozkurt, David Z I Cherney, Justin A Ezekowitz, Meg J Jardine, Sadiya S Khan, Magdalena Madero, Mark J Sarnak, Jozine M Ter Maaten, Michael Cheung, Jennifer M King, Morgan E Grams, Michel Jadoul, Nisha Bansal
Faculty, Staff and Students Publications
Heart failure (HF) and chronic kidney disease (CKD) frequently coexist, which elevates the risks of hospitalization, disease progression, and death. Despite advances in treating each condition independently, many challenges remain in diagnosing and managing them in combination. In March 2024, Kidney Disease: Improving Global Outcomes (KDIGO) held the Controversies Conference on Kidney Disease and Heart Failure: Recent Advances and Current Challenges. Discussions highlighted the complex, bidirectional relationship between HF and CKD, including shared risk factors and overlapping pathophysiology as well as nuances in interpreting biomarkers such as natriuretic peptides and serum creatinine. Sodium-glucose cotransporter-2 inhibitors, renin-angiotensin-aldosterone system inhibitors, and emerging …
Feasibility Of Identifying Factors Related To Alzheimer’S Disease And Related Dementia In Real-World Data, Yu Huang, Qian Li, Aokun Chen, Yongqiu Li, Yu-Neng Chuang, Xia Hu, Serena Jingchuan Guo, Xing He, Yijiang Pang, Jiayu Zhou, Yonghui Wu, Yi Guo, Jiang Bian
Feasibility Of Identifying Factors Related To Alzheimer’S Disease And Related Dementia In Real-World Data, Yu Huang, Qian Li, Aokun Chen, Yongqiu Li, Yu-Neng Chuang, Xia Hu, Serena Jingchuan Guo, Xing He, Yijiang Pang, Jiayu Zhou, Yonghui Wu, Yi Guo, Jiang Bian
Faculty, Staff and Student Publications
Objective: This study aimed to provide a comprehensive understanding of factors associated with Alzheimer's disease (AD) and AD-related dementias (AD/ADRD), which could aid in studies to develop new treatments for AD/ADRD patients and identify high-risk populations for prevention.
Scope and method: In our study, we summarized the risk factors for AD/ADRD by reviewing existing meta-analyses and review articles on risk and preventive factors for AD/ADRD. From this literature review and the identified AD/ADRD factors, we examined the accessibility of these risk and preventive factors in both structured and unstructured Electronic Health Records (EHRs) data.
Results: In total, we extracted 401 …
World Transit Research April 2026 Newsletter, Institute Of Transport Studies Monash University
World Transit Research April 2026 Newsletter, Institute Of Transport Studies Monash University
World Transit Research Newsletter
No abstract provided.
Nigella Sativa Oil-Loaded Treated Dentin Matrix Hydrogel As An Alternative Biomaterial For Direct Pulp Capping: A Systematic Review, Alfin R. Cahyadi, Ayu Annafi, Malika Q. Rahmalia, Adelisa D. Ryani, Tania Saskianti, Harly Prabowo, Nadia Kartikasari, Abil Kurdi, Agus Dahlan
Nigella Sativa Oil-Loaded Treated Dentin Matrix Hydrogel As An Alternative Biomaterial For Direct Pulp Capping: A Systematic Review, Alfin R. Cahyadi, Ayu Annafi, Malika Q. Rahmalia, Adelisa D. Ryani, Tania Saskianti, Harly Prabowo, Nadia Kartikasari, Abil Kurdi, Agus Dahlan
Journal of Dentomaxillofacial Science
Objective: To assess evidence on Treated Dentin Matrix Hydrogel (TDMH) and Nigella sativa oil (NSO), individually or combined, as biomaterials for direct pulp capping (DPC) and their reparative dentin promotion ability. Methods: A systematic search of PubMed, EBSCO, ScienceDirect, and Wiley (January 1, 2018–December 31, 2023) was conducted using MeSH-based terms associated with ``treated dentin matrix hydrogel,'' ``Nigella sativa oil,'' and ``direct pulp capping.'' Eligible studies included in vitro, in vivo, and clinical research evaluating TDMH or NSO for DPC; studies with no outcome data were excluded. Risk-of-bias assessment was performed using ROB2 (clinical) and SYRCLE (animal). Because of …
Oral Health–Related Quality Of Life Following Complete Denture Rehabilitation In Diabetic Edentulous Patients: A 6-Month Prospective Study, Eri Hendra Jubhari, Edy Machmud, Mohammad Dharma Utama, Bahruddin Thalib, Stang Stang, Rifaat Nurrahma, Indah Tresnawati
Oral Health–Related Quality Of Life Following Complete Denture Rehabilitation In Diabetic Edentulous Patients: A 6-Month Prospective Study, Eri Hendra Jubhari, Edy Machmud, Mohammad Dharma Utama, Bahruddin Thalib, Stang Stang, Rifaat Nurrahma, Indah Tresnawati
Journal of Dentomaxillofacial Science
Objective: Edentulism and diabetes mellitus (DM) are associated with impaired oral function and diminished quality of life. Complete denture rehabilitation plays a pivotal role in the restoration of mastication, comfort, and self-confidence. This study aimed to examine changes in oral health–related quality of life (OHRQoL) after complete denture insertion in diabetic edentulous patients using the OHIP-14 and Geriatric Oral Health Assessment Index (GOHAI) questionnaires.
Materials and Methods: This prospective, longitudinal observational study included 25 completely edentulous diabetic patients. Their OHRQoL was evaluated at baseline and at 1, 2, and 6 months postdenture insertion using validated questionnaires, namely, OHIP-14 and GOHAI. …
Determinants Of Toothbrushing Behavior Among 12-Year-Old Children: An Application Of The Health Belief Model, Fitri D. Oktadewi, Riski A. Hidayah, Ryana B. Purnama, Ananda P. Yuliani
Determinants Of Toothbrushing Behavior Among 12-Year-Old Children: An Application Of The Health Belief Model, Fitri D. Oktadewi, Riski A. Hidayah, Ryana B. Purnama, Ananda P. Yuliani
Journal of Dentomaxillofacial Science
Objective: Effective toothbrushing behaviors in school-aged children play an important role in preventing dental and oral health problems. At the age of 12, the behaviors constitute a critical phase in the formation of healthy lifestyle habits. Therefore, this study aimed to analyze the factors that influence toothbrushing behaviors in 12-year-old children based on the Health Belief Model (HBM) theory.
Material and Methods: A total of 92 12-year-old children were selected by cluster sampling method at elementary schools in Banyumas, Central Java. The independent variables included perceived susceptibility, severity, barrier, and benefit in accordance with HBM. The dependent variable comprised toothbrushing …
Euphorbia Tirucalli L. Accelerates Mandibular Bone Healing: Analysis Of Pmns, Fibroblasts, Osteoblasts, And Osteoclasts In Wistar Rats, Florence Meliawaty, Juni Handajani, Heni Susilowati, Poerwati Soetji Rahajoe, Euis Reni Yuslianti, Rahmadaniah Khaerunnisa, Kertamaya Sundawan, Adzra Farah Fajrina, Lorintan Sitepu
Euphorbia Tirucalli L. Accelerates Mandibular Bone Healing: Analysis Of Pmns, Fibroblasts, Osteoblasts, And Osteoclasts In Wistar Rats, Florence Meliawaty, Juni Handajani, Heni Susilowati, Poerwati Soetji Rahajoe, Euis Reni Yuslianti, Rahmadaniah Khaerunnisa, Kertamaya Sundawan, Adzra Farah Fajrina, Lorintan Sitepu
Journal of Dentomaxillofacial Science
Objective: The present study aimed to elucidate the therapeutic potential of Euphorbia tirucalli L. stem extract in accelerating mandibular bone defect healing through the modulation of inflammatory and regenerative cellular responses, including polymorphonuclear cells, fibroblasts, osteoblasts, and osteoclasts in Wistar rats.
Material and Methods: A laboratory-based experimental study with a randomized post-test only control group design was conducted using 40 male Wistar rats. Standardized mandibular defects were created in the symphysis region utilizing a low-speed round bur. The animals were randomly assigned into four groups, including a negative control and three treatment groups receiving topical Euphorbia tirucalli L. stem extract …
Bone Regeneration On Modified Implant Surfaces: A Systematic Review, Irfan Dammar, Ratna S. Dewi, Ira Tanti, Lisa R. Amir, Lilies D. Sulistyanti, Yuniarti Soeroso
Bone Regeneration On Modified Implant Surfaces: A Systematic Review, Irfan Dammar, Ratna S. Dewi, Ira Tanti, Lisa R. Amir, Lilies D. Sulistyanti, Yuniarti Soeroso
Journal of Dentomaxillofacial Science
Objective: To describe effective implant surface modifications (ISMs) that enhance bone regeneration.
Methods: This systematic review involved literature searches in the PubMed, Scopus, and ScienceDirect databases to identify both in vivo and in vitro randomized controlled trials investigating bone regeneration on modified implant surfaces. The search was conducted using predefined population, intervention, comparison, outcome, and study design criteria, eligibility criteria, and relevant MeSH terms. Article selection followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses flow diagram.
Results: Various ISMs were identified, including elastin-like polypeptides, hydroxyapatite, doxycycline, sandblasted large-grit acid-etched, and others. The average bone-to-implant contact (BIC) in experimental …
Curating Black Knowledge In Academic Libraries: A Qualitative Study, Monique Christian-Long
Curating Black Knowledge In Academic Libraries: A Qualitative Study, Monique Christian-Long
Education Policy and Leadership Theses and Dissertations
Academic librarians play a critical role in shaping access to scholarly information. However, the intellectual contributions of African American scholars have often been marginalized in academia through structural inequities, archival gaps, and historical patterns of exclusion. This qualitative study explores how academic librarians understand and use their roles to advance access to African American scholarly contributions. This study is guided by Black Critical Race Theory (Dumas & Ross, 2016) and Ray’s (2019) Theory of Racialized Organizations, and examines how institutional structures, professional norms, and resource allocation influence librarians’ efforts to curate, preserve, and promote Black knowledge. The data was collected …
Jurisdiction Fiction: Is International Shoe Due For A Pennoyer Moment? Part I, Peter B. Rutledge, E. Reed Lemasters, Caleb Z. Morris
Jurisdiction Fiction: Is International Shoe Due For A Pennoyer Moment? Part I, Peter B. Rutledge, E. Reed Lemasters, Caleb Z. Morris
Missouri Law Review
Personal jurisdiction doctrine is a mess. In an attempt to clarify personal jurisdiction doctrine, the Supreme Court has routinely obscured its underlying rationale. That rationale predates the Court’s landmark decision in Pennoyer v. Neff and continues to loom in the background of the most recent post-International Shoe cases. Instead of laying bare that rationale, the doctrine has devolved into a string of proxies built upon proxies—all laboring mightily to avoid stating the obvious: State authority lies at the heart of all personal jurisdiction inquiries. From “physical presence” to “minimum contacts” to “targeting” to “effects” to “relatedness,” all fictions strive to …
The Varying Strength Of Parental Rights, Mark Strasser
The Varying Strength Of Parental Rights, Mark Strasser
Missouri Law Review
The United States Supreme Court has recognized that parental rights implicate fundamental interests and that statutes adversely affecting those rights require close examination. However, the Court has been inconsistent in both its analysis and results when deciding which statutes burdening parental rights nonetheless pass constitutional muster. The Court’s ambivalence and lack of clarity have made parental rights jurisprudence confused and confusing, as illustrated by the dissensus among the state supreme courts regarding which visitation statutes are constitutional. Yet, this jurisprudential quagmire cannot be blamed on one particular decision, as if a single clarification or modification could resolve the problem. Rather, …
An Unnecessary Burden: Why It Is Time To Eliminate Mcdonnell Douglas From Ada Failure-To-Accommodate Claims, Jonathan G. Jain
An Unnecessary Burden: Why It Is Time To Eliminate Mcdonnell Douglas From Ada Failure-To-Accommodate Claims, Jonathan G. Jain
Missouri Law Review
Several strangers sit together in a room, staring at three black lines on a white card. Their task seems simple: choose the line that matches the length of a line printed on a second card. One by one, the strangers correctly choose the matching line, and the task repeats with new white cards and new black lines. The correct answer is always obvious, but after a few rounds, one man suddenly finds himself alone in giving the correct response. What he does not know is that the others have been instructed to begin choosing incorrect lines. Eventually, despite what his …
Product Liability In The Digital Age: A Flexible Framework For Categorizing Technology After Ameer V. Lyft, Andrew Jensen
Product Liability In The Digital Age: A Flexible Framework For Categorizing Technology After Ameer V. Lyft, Andrew Jensen
Missouri Law Review
A single line of code can now cause a car crash, deny a loan, or—as in the case of Ameer v. Lyft—contribute to a man’s death. Traditional product liability law, born in the era of smokestacks and assembly lines, still assumes that only tangible things can be defective products. When software replaces machinery and algorithms make life-or-death decisions, courts face a question: can code itself be a defective product? The answer matters enormously. If courts decline to treat mass-marketed applications as “products,” victims of dangerous software may be left without recourse. On the other hand, if they expand liability too …
Late-Onset Legg-Calvé-Perthes Disease Treated With Varus Derotation Femoral Osteotomy: A Case Report, Mark Gamadia, Sami Habboub, Bianca Gamadia, Himanshu Panchal
Late-Onset Legg-Calvé-Perthes Disease Treated With Varus Derotation Femoral Osteotomy: A Case Report, Mark Gamadia, Sami Habboub, Bianca Gamadia, Himanshu Panchal
Student Publications
Introduction: Legg-Calvé-Perthes disease (LCPD) is categorized as idiopathic avascular necrosis of the femoral head, most common in children between the ages of 5 and 7. Prognosis is strongly influenced by age and lateral pillar classification, with children older than 8 years and those with Herring Group C disease typically experiencing poor outcomes. Delayed diagnosis represents a significant barrier to care, often limiting treatment options and worsening prognosis. This case highlights such a scenario while demonstrating that favorable functional and radiographic results remain achievable through meticulous surgical containment in late-presenting, severe disease.
Case report: An 11-year-old boy with no history of …
Development And Evaluation Of An Mpas-Based Urban Modeling System For The New York City Region, Marco S. Yu, Kristian Rice
Development And Evaluation Of An Mpas-Based Urban Modeling System For The New York City Region, Marco S. Yu, Kristian Rice
Publications and Research
Complex geometry and varying land cover make urban environments difficult to simulate accurately. This research presents a performance evaluation of the newly developed urban modeling system in the Model for Prediction Across Scales (MPAS). Weather over the New York metropolitan area during June 2018 was simulated using supercomputing resources and the new urban modeling system. Modeled 2-m air temperature was compared with historical hourly observations from five NYC Mesonet stations, one located in each of the five boroughs. Comparison showed that the model follows the timing of warming and cooling well, but overestimates the magnitude of temperature swings at peaks …
Geopolitical Myths And Symbols In Independent Kazakhstan: The Case Of The Head Of Kenesary Khan, Assem Maralova
Geopolitical Myths And Symbols In Independent Kazakhstan: The Case Of The Head Of Kenesary Khan, Assem Maralova
Dartmouth College Master’s Theses
This thesis examines the political myth surrounding the severed head of Kenesary Khan, the last khan of the Kazakh Khanate, and its significance in contemporary Kazakhstan. Focusing on historiographical debates, media narratives, and collective memory, the study analyzes how the unresolved fate of Kenesary Khan’s head functions as a symbolic site of post-colonial identity formation. Drawing on archival sources, scholarly literature, and cultural media, the research demonstrates that the myth operates as a tool for negotiating sovereignty, historical justice, and national memory in Kazakhstan’s nation-building process.
Dark Wave - Comics And Transgender Studies In Practice, Mieke Vanderveen
Dark Wave - Comics And Transgender Studies In Practice, Mieke Vanderveen
Dartmouth College Master’s Theses
This is a thesis in two parts. Its goal is to provoke the intersection of superhero comics and transgender studies in order to interrogate the parallels between those two identities and explore ways in which pairing them together can strengthen each other narratively and academically. Rather than seeking an answer to a question, the project as a whole serves as a way of communicating trans internalities from a transfeminine perspective in a format that brings the issues to the forefront of the narrative in an in-depth and entertaining way. The result is hopefully a coherent artistic work that achieves those …
Active Measures, Jacob Campbell
Active Measures, Jacob Campbell
Dartmouth College Master’s Theses
Active Measures is a Cold War era espionage drama, written for television. In the story, two mid-level agents in a centrally located, yet functionally unimportant CIA station are scapegoated after a high-level defection is sabotaged by an unknown mole, resulting in the defector’s death. Having found intelligence sewn into the defector’s jacket, the agents, John O’Neil and Sam Rosen, attempt to pursue his lead and clear their names while under internal investigation.
The story is influenced by the moral ambiguity of espionage novels by Alan Furst and John le Carre, and the television series The Americans. Like these predecessors, …
Ai Interpretability In Healthcare Communication, Ananya Jeyappragash
Ai Interpretability In Healthcare Communication, Ananya Jeyappragash
Dartmouth College Master’s Theses
Artificial intelligence has increasingly been adopted in healthcare, largely for specialized tasks and under significant human oversight. The use of large black-box systems raises important concerns about transparency in high-stakes environments such as clinical decision-making. Clinical communication is fundamentally human-centered, and failures in judgment can have serious consequences for patient care. Overestimating the reasoning abilities of large language models may lead to undue trust in fabricated or “hallucinated” outputs, while rejecting AI-assisted tools altogether may preserve inefficient workflows and contribute to missed or delayed diagnoses. These concerns reflect a broader tradeoff between accuracy and interpretability: although more complex models may …
Not Forgetting The Fathers: A Qualitative Narrative Review Exploring The Involvement And Psychological Well-Being Of Fathers In The Neonatal Intensive Care Unit., Kayleigh Gahagan, Kevin Hambridge, Matt Carey
Not Forgetting The Fathers: A Qualitative Narrative Review Exploring The Involvement And Psychological Well-Being Of Fathers In The Neonatal Intensive Care Unit., Kayleigh Gahagan, Kevin Hambridge, Matt Carey
School of Nursing and Midwifery
BackgroundDespite policy commitments to family-centred care, neonatal services often remain implicitly structured around maternal presence. Fathers, although increasingly acknowledged as vital to early child development, frequently experience feelings of exclusion throughout the neonatal journey, from antenatal care through to the neonatal intensive care unit.AimThis review explores how fathers experience involvement and psychological wellbeing during their infant’s admission to a neonatal intensive care unit.MethodsA narrative review of qualitative studies was conducted using the SPIDER framework to guide the search strategy. The nine included studies, which met the inclusion criteria were identified via searching the databases CINAHL, PubMed, and PsycINFO. Studies were …
Neutrophil-Microglia Interaction Drives Motor Dysfunction In A Neuromyelitis Optica Model Induced By Subarachnoid Aqp4-Igg, Fangfang Qi, Vanda A Lennon, Shunyi Zhao, Yong Guo, Husheng Ding, Caiyun Liu, Whitney M Bartley, Tingjun Chen, Claudia F Lucchinetti, Long-Jun Wu
Neutrophil-Microglia Interaction Drives Motor Dysfunction In A Neuromyelitis Optica Model Induced By Subarachnoid Aqp4-Igg, Fangfang Qi, Vanda A Lennon, Shunyi Zhao, Yong Guo, Husheng Ding, Caiyun Liu, Whitney M Bartley, Tingjun Chen, Claudia F Lucchinetti, Long-Jun Wu
Faculty, Staff and Student Publications
Neutrophils and neutrophil extracellular traps (NETs) contribute to early neuromyelitis optica (NMO) histopathology initiated by IgG targeting astrocytic aquaporin-4 (AQP4) water channels. Yet, the mechanisms underlying neutrophil recruitment and their pathogenic roles in disease progression remain unclear. To investigate molecular-cellular events preceding classical complement cascade activation in a mouse NMO model, we continuously infused, via spinal subarachnoid route, a non-complement-activating mouse monoclonal AQP4-IgG. Parenchymal infiltration of netting neutrophils containing C5a ensued with microglial activation and motor impairment but no blood-brain barrier leakage. Motor impairment and neuronal dysfunction both reversed when AQP4-IgG infusion stopped. Two-photon microscopy and electron microscopy-based reconstructions revealed …
Structural-Functional Analyses Of The Huntingtin/Hap40 Complex In Drosophila And Humans, Stephen M Farmer, Amanda Solbach, Shiyu Xu, Beatriz Rios, Xin Ye, Amy Gao, Daniela Covarrubias, Yue Yu, Lili Ye, Vicky Chuong, Erin Furr Stimming, Haiqing Zhao, Sheng Zhang
Structural-Functional Analyses Of The Huntingtin/Hap40 Complex In Drosophila And Humans, Stephen M Farmer, Amanda Solbach, Shiyu Xu, Beatriz Rios, Xin Ye, Amy Gao, Daniela Covarrubias, Yue Yu, Lili Ye, Vicky Chuong, Erin Furr Stimming, Haiqing Zhao, Sheng Zhang
Faculty, Staff and Student Publications
Huntington's disease (HD) is a neurodegenerative disorder caused by an abnormal CAG expansion in the Huntingtin (HTT) gene. Given its simple genetic cause but complex pathogenic mechanisms, interest in targeting HTT for HD treatment is growing, necessitating a clear understanding of HTT regulation. HTT protein primarily exists in a core complex with HAP40, forming a highly ordered structure with two large globular domains connected by a bridge. We previously demonstrated that HAP40 is conserved in
Local Institutions Mediate Effects Of Land Scarcity In Indigenous Territories In Amazonia, Ana Lucía Araujo Raurau, Oliver T. Coomes
Local Institutions Mediate Effects Of Land Scarcity In Indigenous Territories In Amazonia, Ana Lucía Araujo Raurau, Oliver T. Coomes
Student Publications [Scholarly]
Indigenous territories in Amazonia sustain forest cover through the practice of swidden-fallow agriculture, yet declining land availability threatens both the ecological sustainability of this agricultural system and its contributions to community livelihoods. While scholars recognize land scarcity’s potential to drive transformations in shifting cultivation systems, we lack a systematic understanding of how local institutional frameworks shape heterogeneous responses to resource constraints. This study examines how land access mechanisms, distribution dynamics and property regimes among Indigenous communities mediate experiences of and adaptations to land scarcity in the Peruvian Amazon. We conducted a comparative case study of Solidaridad and Tamboruna, two land-scarce …
Machine Learning And Multisensor Data Fusion For Forest Above Ground Biomass Estimation In Arkansas, Abdullah Al Saim, Mohamed Aly
Machine Learning And Multisensor Data Fusion For Forest Above Ground Biomass Estimation In Arkansas, Abdullah Al Saim, Mohamed Aly
Geosciences Faculty Publications and Presentations
Forests are essential for biodiversity conservation, climate change, natural education, scientific research, and carbon sequestration. This study uses machine learning-based Random Forest (RF) regression to estimate the Above Ground Biomass (AGB) of the Ozark and Ouachita forests at a 10-meter resolution by combining data from Sentinel-2, Sentinel-1, and GEDI (Global Ecosystem Dynamics Investigation) on Google Earth Engine. The RF model included 34 out of 154 variables representing topographical, spectral, and textural factors demonstrating strong correlations with measured biomass. The RF model showed strong performance with R-squared and RMSE values of 0.95 and 18.46 for the training dataset and 0.75 and …
Aht Diagnoses: The Influences Of Clinical Presentation And Evidence Of Impact, Ruairi Smith-Dewey, Angela Bachim, Colleen Bressler, Kristine Campbell, Lori Frasier, Christopher Greeley, Danielle Horton, Nicole Johnson, Jan Leonard, Megan M Letson, Caitlin Mcnamara, Ashley Sherman, Shalon Nienow, Stuart Sommers, Joanne N Wood, James Anderst
Aht Diagnoses: The Influences Of Clinical Presentation And Evidence Of Impact, Ruairi Smith-Dewey, Angela Bachim, Colleen Bressler, Kristine Campbell, Lori Frasier, Christopher Greeley, Danielle Horton, Nicole Johnson, Jan Leonard, Megan M Letson, Caitlin Mcnamara, Ashley Sherman, Shalon Nienow, Stuart Sommers, Joanne N Wood, James Anderst
Faculty, Staff and Students Publications
Background: The frequency of abusive head trauma (AHT) diagnoses by child abuse pediatricians (CAPs), especially regarding external evidence of head impact, has been questioned.
Objectives: To compare CAP diagnoses in subjects with subdural hemorrhage (SDH) across clinical presentations, including subgroups with and without external evidence of head impact. Additionally, we aimed to describe subjects with SDH and concomitant suspicious injuries (CSI) without evidence of head impact.
Participants and setting: Multicenter retrospective study including subjects < 24 months old with SDH.
Methods: Subjects were divided into groups based on clinical presentations: Ill SDH only, Non-ill SDH only, and SDH + CSI. Groups were subcategorized based on presence/absence …