Digital Commons Network^™

Genetic And Environmental Variation In Continuous Phenotypes In The Abcd Study®, Hermine H M Maes, Dana M Lapato, J Eric Schmitt, Monica Luciana, Marie T Banich, James M Bjork, John K Hewitt, Pamela A Madden, Andrew C Heath, Deanna M Barch, Wes K Thompson, William G Iacono, Michael C Neale

2020-Current year OA Pubs

Twin studies yield valuable insights into the sources of variation, covariation and causation in human traits. The ABCD Study® (abcdstudy.org) was designed to take advantage of four universities known for their twin research, neuroimaging, population-based sampling, and expertise in genetic epidemiology so that representative twin studies could be performed. In this paper we use the twin data to: (i) provide initial estimates of heritability for the wide range of phenotypes assessed in the ABCD Study using a consistent direct variance estimation approach, assuring that both data and methodology are sound; and (ii) provide an online resource for researchers that can …

Hemoglobin Concentration Impacts Viscoelastic Hemostatic Assays In Icu Admitted Patients, David J Roh, Tiffany R Chang, Aditya Kumar, Devin Burke, Glenda Torres, Katherine Xu, Winni Yang, Azzurra Cottarelli, Ernest Moore, Angela Sauaia, Kirk Hansen, Angela Velazquez, Amelia Boehme, Athina Vrosgou, Shivani Ghoshal, Soojin Park, Sachin Agarwal, Jan Claassen, E Sander Connolly, Gebhard Wagener, Richard O Francis, Eldad Hod

Faculty, Staff and Student Publications

Objectives: Low hemoglobin concentration impairs clinical hemostasis across several diseases. It is unclear whether hemoglobin impacts laboratory functional coagulation assessments. We evaluated the relationship of hemoglobin concentration on viscoelastic hemostatic assays in intracerebral hemorrhage (ICH) and perioperative patients admitted to an ICU.

Design: Observational cohort study and separate in vitro laboratory study.

Setting: Multicenter tertiary referral ICUs.

Patients: Two acute ICH cohorts receiving distinct testing modalities: rotational thromboelastometry (ROTEM) and thromboelastography (TEG), and a third surgical ICU cohort receiving ROTEM were evaluated to assess the generalizability of findings across disease processes and testing platforms. A separate in vitro ROTEM laboratory …

Wallaby Pilot Survey: H I Gas Kinematics Of Galaxy Pairs In Cluster Environment, Shin-Jeong Kim, Se-Heon Oh, Jing Wang, Lister Staveley-Smith, Bärbel S. Koribalski, Minsu Kim, Hye-Jin Park, Shinna Kim, Kristine Spekkens, Juan P. Madrid

Physics & Astronomy Faculty Publications

We examine the H I gas kinematics of galaxy pairs in two clusters and a group using Australian Square Kilometre Array Pathfinder (ASKAP) WALLABY pilot survey observations. We compare the H I properties of galaxy pair candidates in the Hydra I and Norma clusters, and the NGC 4636 group, with those of non-paired control galaxies selected in the same fields. We perform H I profile decomposition of the sample galaxies using a tool, BAYGAUD, which allows us to deblend a line-of-sight velocity profile with an optimal number of Gaussian components. We construct H I superprofiles of the sample galaxies via …

Enhanced Two-Step Deep-Learning Approach For Electromagnetic-Inverse-Scattering Problems: Frequency Extrapolation And Scatterer Reconstruction, Huan Huan Zhang, He Ming Yao, Lijun Jiang, Michael Ng

Electrical and Computer Engineering Faculty Research & Creative Works

The electromagnetic-inverse-scattering (EMIS) problem is solved by a novel two-step deep-learning (DL) approach in this article. The newly proposed two-step DL approach not only predicts the multifrequency EM scattered field, but also overcomes the limitation of the conventional methods for solving EMIS problems, such as expensive computational cost, strong ill-conditions, and invalidity on high contrast. In the first step, the complex-valued deep residual convolutional neural network (DRCNN) is utilized to predict multifrequency EM scattered fields only using single-frequency EM scattered field information. Based on a new complex-valued deep convolutional encoder-decoder (DCED) structure, the second step utilizes the obtained multifrequency EM …

An Evaluation Of Avian Influenza Virus Whole-Genome Sequencing Approaches Using Nanopore Technology, Hon S. Ip, Sarah Uhm, Mary Lea Killian, Mia K. Torchetti

United States Department of Agriculture Wildlife Services: Staff Publications

As exemplified by the global response to the SARS-CoV-2 pandemic, whole-genome sequencing played an important role in monitoring the evolution of novel viral variants and provided guidance on potential antiviral treatments. The recent rapid and extensive introduction and spread of highly pathogenic avian influenza virus in Europe, North America, and elsewhere raises the need for similarly rapid sequencing to aid in appropriate response and mitigation activities. To facilitate this objective, we investigate a next-generation sequencing platform that uses a portable nanopore sequencing device to generate and present data in real time. This platform offers the potential to extend in-house sequencing …

The Effect Of An American Heart Association–Approved Exercise Regimen On Burnout In Nurse Practitioners And Physician Assistants Working In Emergency Departments, Michelle Lee Johnson

Electronic Theses and Dissertations

Burnout is a widely known state of physical and emotional fatigue previously noted to affect as many as 60% of healthcare providers, but one that is understudied in nurse practitioners and physician assistants working in emergency departments. It is imperative that the providers of healthcare recognize in themselves signs of burnout and have resources available to mitigate the condition. A pretest–posttest, quasi-experimental, nonequivalent control group, descriptive research design with descriptive statistics analysis was used to analyze answers to an email-based survey sent to nurse practitioners and physician assistants working for one large emergency medicine staffing company. The intent of this …

Mindfulness Based Stress Reduction Techniques In Chronic Illness, Anna Celia Gil

Electronic Theses and Dissertations

Abstract

Chronic stress and its effect on both physical and mental health have been a topic of increasing interest in the past several decades. There is mounting evidence that recurrent, persistent stress of both a physiologic and psychological nature leads to a dysfunction in the hypothalamic pituitary axis (HPA), the system which helps the body recover and adapt to short term stress. In long term stress, this HPA dysfunction leads to impairment of the immune and neuroendocrine systems resulting in chronic low-grade inflammation. This type of chronic inflammation acts as a precursor to several chronic illnesses such as diabetes, hypertension, …

Female Ex-Offenders Transitioning Into Society, Stacey L. Forte

Electronic Theses and Dissertations

The purpose of this qualitative study was to examine female ex-offenders’ perceptions of their lived experience(s) while transitioning into society after incarceration. This study examined risk factors that female ex-offenders faced while transitioning into society asking the question, “What are the lived experiences of female ex-offenders who utilized transitional housing for reentry with regard to their perception of the benefits of certain services/offerings and staff support?” Nine participants were part of the study ranging from 25–64 years of age, with the majority being between the ages of 25 and 55 years old, residing originally in five different states. Sixty percent …

On Viscoelastic Fiber Jet Formation By Forcespinning At High Rotation Rate, Daniel N. Riahi, Saulo Orizaga

School of Mathematical & Statistical Sciences Faculty Publications

We consider a nonlinear three-dimensional viscoelastic fiber jet that is generated during a forcespinning process. We provide a particular case for such a rotating jet at a high rotation rate. We use a viscoelastic constitutive model for the jet equations and then applying a new slender body approach, we continue with proper scaling and perturbation technique to develop a new model for such a jet system. We find that the profiles for jet quantities versus arc length are notably different from all those in related studies reported before for either high or low rotation rates. In particular, jet radius first …

Psychosocial, Medical, And Demographic Variables Associated With Parent Mealtime Behavior In Young Children Recently Diagnosed With Type 1 Diabetes, Caroline Gonynor, Christine Wang, Carrie Tully, Maureen Monaghan, Randi Streisand, Marisa E Hilliard

Faculty, Staff and Students Publications

OBJECTIVE: Managing young children's mealtime concerns can be challenging after type 1 diabetes (T1D) diagnosis because of developmental factors and diabetes management demands. To identify potential intervention targets, we evaluated medical, psychosocial, and demographic factors in relation to parents' engagement in problem mealtime behaviors (e.g., pressure to eat, restriction).

METHOD: Parents (N = 157) of young children (age 1-6 years) reported on psychosocial variables (parent fear of hypoglycemia, family functioning, parent problem solving, and parents' problem mealtime behavior frequency and perceptions of being problematic) within 2 months after T1D diagnosis. Hierarchical regression analyses examined associations among psychosocial variables, demographics (child …

World Transit Research February 2023 Newsletter, Institute Of Transport Studies Monash University

World Transit Research Newsletter

No abstract provided.

Automated Field-In-Field Whole Brain Radiotherapy Planning, Kai Huang, Soleil Hernandez, Chenyang Wang, Callistus Nguyen, Tina Marie Briere, Carlos Cardenas, Laurence Court, Yao Xiao

Faculty, Staff and Student Publications

PURPOSE: We developed and tested an automatic field-in-field (FIF) solution for whole-brain radiotherapy (WBRT) planning that creates a homogeneous dose distribution by minimizing hotspots, resulting in clinically acceptable plans.

METHODS: A configurable auto-planning algorithm was developed to automatically generate FIF WBRT plans independent of the treatment planning system. Configurable parameters include the definition of hotspots, target volume, maximum number of subfields, and minimum number of monitor units per field. This algorithm iteratively identifies a hotspot, creates two opposing subfields, calculates the dose, and optimizes the beam weight based on user-configured constraints of dose-volume histogram coverage and least-squared cost functions. The …

Erratum: "Aapm Task Group Report 303 Endorsed By The Abs: Mri Implementation In Hdr Brachytherapy-Considerations From Simulation To Treatment", Joann Prisciandaro, Jacqueline Esthappan Zoberi, Gil'ad Cohen, Yusung Kim, Perry Johnson, Eric Paulson, William Song, Ken-Pin Hwang, Beth Erickson, Sushil Beriwal, Christian Kirisits, Firas Mourtada

Faculty, Staff and Student Publications

No abstract provided.

The Effects Of Robot Voices And Appearances On Users' Emotion Recognition And Subjective Perception, Sangjin Ko, Jaclyn A. Barnes, Jiayuan Dong, Chung Hyuk Park, Ayanna Howard, Myounghoon Jeon

Michigan Tech Publications, Part 1

As the influence of social robots in people's daily lives grows, research on understanding people's perception of robots including sociability, trust, acceptance, and preference becomes more pervasive. Research has considered visual, vocal, or tactile cues to express robots' emotions, whereas little research has provided a holistic view in examining the interactions among different factors influencing emotion perception. We investigated multiple facets of user perception on robots during a conversational task by varying the robots' voice types, appearances, and emotions. In our experiment, 20 participants interacted with two robots having four different voice types. While participants were reading fairy tales to …

Australian Consumers’ Attitudes Towards Sustainable Diet Practices Regarding Food Waste, Food Processing, And The Health Aspects Of Diet: A Cross Sectional Survey, Janelle D. Healy, Satvinder S. Dhaliwal, Christina M. Pollard, Piyush Sharma, Clare Whitton, Lauren C. Blekkenhorst, Carol J. Boushey, Jane A. Scott, Deborah A. Kerr

Research outputs 2022 to 2026

Environmentally sustainable diets are increasingly aspired to in food-based dietary guidelines across the world. However, little is known about consumer attitudes toward these diets when making food decisions. This study aimed to identify the demographic characteristics of Australian adults based on the level of attention they paid to the healthfulness of their diet, their consideration of the level of food processing, and their concern about household food waste and sustainable packaging disposal. Adults aged from 18 to over 75 years (n = 540) were surveyed online. Thirty-seven percent were concerned about sustainable food waste, 28 % considered the level of …

Digital Twin Applications In 3d Concrete Printing, Yuxin Wang, Farhad Aslani, Arcady Dyskin, Elena Pasternak

Research outputs 2022 to 2026

The benefits of 3D concrete printing (3DCP) include reducing construction time and costs, providing design freedom, and being environmentally friendly. This technology is expected to be effective in addressing the global house shortage. This review highlights the main 3DCP applications and four critical challenges. It is proposed to combine 3D concrete printing with Digital Twin (DT) technology to meet the challenges the 3DCP faces and improve quality and sustainability. This paper provides a critical review of research into the application of DT technology in 3DCP, categorize the applications and directions proposed according to different lifecycles, and explore the possibility of …

Corticospinal And Intracortical Responses From Both Motor Cortices Following Unilateral Concentric Versus Eccentric Contractions, Onno Van Der Groen, Christopher Latella, Kazunori Nosaka, Dylan Edwards, Wei Peng Teo, Janet L. Taylor

Research outputs 2022 to 2026

Cross-education is the phenomenon where training of one limb can cause neuromuscular adaptations in the opposite untrained limb. This effect has been reported to be greater after eccentric (ECC) than concentric (CON) strength training; however, the underpinning neurophysiological mechanisms remain unclear. Thus, we compared responses to transcranial magnetic stimulation (TMS) in both motor cortices following single sessions of unilateral ECC and CON exercise of the elbow flexors. Fourteen healthy adults performed three sets of 10 ECC and CON right elbow flexor contractions at 75 % of respective maximum on separate days. Elbow flexor maximal voluntary isometric contraction (MVIC) torques were …

Impact Of The Skill Shortage On The Construction Supply Chain Performance In Australia, Ming Juan Ding, Ferry Jie, Sommala Sisombat, Bala S. Bandlamudi

Research outputs 2022 to 2026

The purpose of this paper is to investigate how the skill shortage impacts the performance of the construction supply chain in Australia. The study has adopted a quantitative research method. The quantitative data were collected by conducting a survey of employees who work in construction companies in Australia. A regression analysis was used to analyze the data from 113 respondents. The findings of the study reveal that the construction sector in Australia has high labour costs, but workers are still thinking they are not getting paid enough and cannot invest more in themselves to improve their skills. There is a …

Prediction Models Of Shielding Effectiveness Of Carbon Fibre Reinforced Cement-Based Composites Against Electromagnetic Interference, Shilpa Narayanan, Yifan Zhang, Farhad Aslani

Research outputs 2022 to 2026

With the rapid development of communication technology as well as a rapid rise in the usage of electronic devices, a growth of concerns over unintentional electromagnetic interference emitted by these devices has been witnessed. Pioneer researchers have deeply studied the relationship between the shielding effectiveness and a few mixed design parameters for cementitious composites incoporating carbon fibres by conducting physical experiments. This paper, therefore, aims to develop and propose a series of prediction models for the shielding effectiveness of cementitious composites involving carbon fibres using frequency and mixed design parameters, such as the water-to-cement ratio, fibre content, sand-to-cement ratio and …

Validity And Reliability Of Inertial Measurement System For Linear Movement Velocity In Flywheel Squat Exercise, Sergio Maroto-Izquierdo, Kazunori Nosaka, Jesús Alarcón-Gómez, Fernando Martín-Rivera

Research outputs 2022 to 2026

The aim of this study was to examine the validity and reliability of an Inertial Measurement System integrated into a secondary pulley (IMS) for determining linear velocity during flywheel squat exercises. Thirty-one male participants who were highly experienced in a flywheel resistance exercise training performed flywheel squat exercises with three incremental loads, and mean velocity (MV), mean propulsive velocity (MPV) and max velocity (Vmax) of the exercises were simultaneously recorded with a validated linear encoder and the IMS, in two different sessions. Validity was analyzed using ordinary least products regression (OLP), Lin’s concordance correlation coefficient (CCC), and Hedge’s g for …

Maternal Western Diet Is Associated With Distinct Preclinical Pediatric Nafld Phenotypes In Juvenile Nonhuman Primate Offspring, Michael J Nash, Evgenia Dobrinskikh, Rachel C Janssen, Mark A Lovell, Deborah A Schady, Claire Levek, Kenneth L Jones, Angelo D'Alessandro, Paul Kievit, Kjersti M Aagaard, Carrie E Mccurdy, Maureen Gannon, Jacob E Friedman, Stephanie R Wesolowski

Faculty, Staff and Students Publications

Pediatric NAFLD has distinct and variable pathology, yet causation remains unclear. We have shown that maternal Western-style diet (mWSD) compared with maternal chow diet (CD) consumption in nonhuman primates produces hepatic injury and steatosis in fetal offspring. Here, we define the role of mWSD and postweaning Western-style diet (pwWSD) exposures on molecular mechanisms linked to NAFLD development in a cohort of 3-year-old juvenile nonhuman primates offspring exposed to maternal CD or mWSD followed by CD or Western-style diet after weaning. We used histologic, transcriptomic, and metabolomic analyses to identify hepatic pathways regulating NAFLD. Offspring exposed to mWSD showed increased hepatic …

Beyond Varices: Complications Of Cirrhotic Portal Hypertension In Pediatrics, Anna M Banc-Husu, Henry Shiau, Peace Dike, Benjamin L Shneider

Faculty, Staff and Students Publications

Complications of cirrhotic portal hypertension (PHTN) in children are broad and include clinical manifestations ranging from variceal hemorrhage, hepatic encephalopathy (HE), ascites, spontaneous bacterial peritonitis (SBP), and hepatorenal syndrome (HRS) to less common conditions such as hepatopulmonary syndrome, portopulmonary hypertension, and cirrhotic cardiomyopathy. The approaches to the diagnosis and management of these complications have become standard of practice in adults with cirrhosis with many guidance statements available. However, there is limited literature on the diagnosis and management of these complications of PHTN in children with much of the current guidance available focused on variceal hemorrhage. The aim of this review …

Superior Verbal Learning And Memory In Pediatric Brain Tumor Survivors Treated With Proton Versus Photon Radiotherapy, Lisa E Mash, Lisa S Kahalley, M Fatih Okcu, David R Grosshans, Arnold C Paulino, Heather Stancel, Luz De Leon, Elisabeth Wilde, Nilesh Desai, Zili D Chu, William E Whitehead, Murali Chintagumpala, Kimberly P Raghubar

Faculty, Staff and Student Publications

OBJECTIVE: Radiotherapy for pediatric brain tumor has been associated with late cognitive effects. Compared to conventional photon radiotherapy (XRT), proton radiotherapy (PRT) delivers lower doses of radiation to healthy brain tissue. PRT has been associated with improved long-term cognitive outcomes compared to XRT. However, there is limited research comparing the effects of XRT and PRT on verbal memory.

METHOD: Survivors of pediatric brain tumor treated with either XRT (

RESULTS: Overall, patients receiving PRT demonstrated superior verbal learning and recall compared to those treated with XRT. Encoding and retrieval deficits were more common in the XRT group than the PRT …

A Novel Data-Driven Method For Two-Dimensional Angles Finding Via Uniform Rectangular Array With Automatic Pairing, Yanming Zhang, Lijun Jiang

Electrical and Computer Engineering Faculty Research & Creative Works

A new hybrid dynamic mode decomposition (HDMD) algorithm is proposed to estimate the azimuth and elevation angles of multiple independent sources for two-dimensional (2D) massive MIMO systems with the uniform rectangular array (URA). To this end, the proposed hybrid scheme integrates the modified DMD with the augmented DMD. By treating the received data as spatial-spatial correlated signals, the modified DMD is first used to decompose these signals into spatial DMD spectrum and corresponding spatial dynamic modes. The obtained spatial DMD spectrum directly yields the electrical angle in the y-direction. Then, the corresponding electrical angle in the x-direction is computed using …

The Disembodied First Amendment, Nathan Cortez, William M. Sage

Faculty Scholarship

First Amendment doctrine is becoming disembodied—increasingly detached from human speakers and listeners. Corporations claim that their speech rights limit government regulation of everything from product labeling to marketing to ordinary business licensing. Courts extend protections to commercial speech that ordinarily extended only to core political and religious speech. And now, we are told, automated information generated for cryptocurrencies, robocalling, and social media bots are also protected speech under the Constitution. Where does it end? It begins, no doubt, with corporate and commercial speech. We show, however, that heightened protection for corporate and commercial speech is built on several “artifices” - …

Water-Cased Kicker Charges For Use In Explosive Demolition, Rachel L. Bauer, Paul Pitzel, Emily M. Johnson, Catherine E. Johnson

Mining Engineering Faculty Research & Creative Works

Demolition Projects Involving Explosives Often Incorporate Cutting Charges to Sever Columns in Conjunction with Kicker Charges that "Move" the Columns Out of Alignment. Traditional Kicker Charges Use Dynamite Secured to the Column above a Linear-Shaped Cutting Charge. This Study Investigates the Use of Water-Cased Kicker Charges for Use in Explosive Demolition. the Goal is to Reduce the Fragmentation of Steel Members and the Quantity of Explosive Needed Due to the Increased Density, Incompressibility, and Impedance Mismatch Water Provides. Simulations and Experimental Tests Were Utilized to Determine What Type of Charges Provide the Optimal Column Movement and Water Placement. Water Charges …

Origin And Evolution Of Marsupial-Specific Imprinting Clusters Through Lineage-Specific Gene Duplications And Acquisition Of Promoter Differential Methylation, Wenqi Cao, Kory C. Douglas, Paul B. Samollow, John Vandeberg, Xu Wang, Andrew G. Clark

School of Medicine Publications

Genomic imprinting is a parent-of-origin-specific expression phenomenon that plays fundamental roles in many biological processes. In animals, imprinting is only observed in therian mammals, with ∼200 imprinted genes known in humans and mice. The imprinting pattern in marsupials has been minimally investigated by examining orthologs to known eutherian imprinted genes. To identify marsupial-specific imprinting in an unbiased way, we performed RNA-seq studies on samples of fetal brain and placenta from the reciprocal cross progeny of two laboratory opossum stocks. We inferred allele-specific expression for >3,000 expressed genes and discovered/validated 13 imprinted genes, including three previously known imprinted genes, Igf2r, Peg10, …

Toxin Induced Parkinsonism And Hospitalization Related Adverse Outcome Mitigation For Parkinson’S Disease: A Comprehensive Review, Kenneth R. Dalton, Charles J. Kidd, Nawaz Hack

School of Medicine Publications

Patients with Parkinson’s disease admitted to the hospital have unique presentations. This unique subset of patients requires a multidisciplinary approach with a knowledge-based care team that can demonstrate awareness of complications specific to Parkinson’s disease to reduce critical care admissions, morbidity, and mortality. Early recognition of toxic exposures, medication withdrawals, or medication-induced symptoms can reduce morbidity and mortality. This review can assist in the critical assessment of new or exacerbating Parkinson’s disease symptoms.

Customised Multi-Energy Pricing: Model And Solutions, Qiuyi Hong, Fanlin Meng, Jian Liu

Electrical and Computer Engineering Faculty Research & Creative Works

With the increasing interdependence among energies (e.g., electricity, natural gas and heat) and the development of a decentralized energy system, a novel retail pricing scheme in the multi-energy market is demanded. Therefore, the problem of designing a customized multi-energy pricing scheme for energy retailers is investigated in this paper. In particular, the proposed pricing scheme is formulated as a bilevel optimization problem. At the upper level, the energy retailer (leader) aims to maximize its profit. Microgrids (followers) equipped with energy converters, storage, renewable energy sources (RES) and demand response (DR) programs are located at the lower level and minimize their …

Guest Editorial: Transition Towards Deep Decarbonisation Of Modern Energy Systems, Yujian Ye, Can Wan, Chenghong Gu, Dan Wu, Goran Strbac, Hongjian Sun, Peng Zhang, Rui Bo, Yi Tang, Zhongbei Tian

Electrical and Computer Engineering Faculty Research & Creative Works

No abstract provided.