Digital Commons Network^™

Volume Electron Microscopy Reveals Heterogeneity Of The Hemostatic Response In Veins And Arteries, Maurizio Tomaiuolo, Meghan E. Roberts, Jenna R. Severa, Christopher D. Mansi, Brenna B. Y. Mathers, Anna Mannix, Trace A Christensen, Lawrence F Brass, Talid Sinno, Timothy J. Stalker

Cardeza Foundation for Hematologic Research

Intravital imaging studies have provided insights into the spatial and temporal variations of platelet activation and thrombin generation that occur during hemostasis; however, these studies are generally limited to small vessels due to the practical limitations of imaging in thicker tissues. Recent advances in cleared tissue fluorescence imaging as well as volume electron microscopy (vEM) coupled with machine learning-based image segmentation provide an opportunity for analysis of the 3-dimensional structure of complex tissues. We utilized these technologies to examine hemostatic plugs from murine jugular veins and carotid arteries to investigate the spatial distribution of platelet activation and biochemical responses in …

Comparison Of Early-, Average-, And Late-Onset Pancreatic Cancer In A Multi-Site Cancer Center: Treatment Patterns And Outcomes, Chirag K. Patel, Jimmy J. Hwang, Mohamed E. Salem, Kunal C. Kadakia

Journal of Patient-Centered Research and Reviews

Purpose: The aim of this study was to investigate treatment and outcomes differences, as well as predictors of early mortality, among early-onset pancreatic adenocarcinoma (EOPC, ≤ 50 years), average-onset pancreatic adenocarcinoma (AOPC, 51-69 years), and late-onset pancreatic adenocarcinoma (LOPC, ≥ 70 years).

Methods: We retrospectively analyzed 333 patients with pancreatic adenocarcinoma at a multi-site center between 2011-2018. Clinical, demographic, and treatment variables were compared by age group. Predictors of early mortality (death ≤ 6 months from diagnosis) were assessed using multivariable logistic regression. Survival outcomes were evaluated using Kaplan-Meier analyses.

Results: Among the 333 patients, 56% were male, and the …

A Governance-Aware Multi-Agent Framework For Enhancing Fairness & Temporal Accuracy In Disaster Response Systems, Md. Ashfaqur Rahman

Theses and Dissertations

Large Language Models (LLMs) have demonstrated significant potential in disaster-response decision support, however, their deployment in high-stakes humanitarian settings raises critical concerns regarding factual reliability, fairness, temporal validity, and governance compliance. Hallucinated outputs, demographic bias, and outdated recommendations can directly impact vulnerable populations and undermine public trust. This dissertation proposes a governance-aware multi-agent framework designed to enhance fairness and temporal accuracy in disaster-response systems through structured Retrieval-Augmented Generation (RAG), verification-driven orchestration, and adaptive correction mechanisms.The proposed architecture decomposes response generation into specialized agents responsible for real-time retrieval, fact-checking, bias auditing, temporal validation, threshold-based correction, and monitoring. By embedding governance constraints …

Smart Pediatric Oncology Tracker Of Symptoms (Spots), A Web-Based Interface For The Pediatric Pro-Ctcae: Development And Usability Study, Stacey Crane, Deevakar Rogith, Melody Hellsten, Andrew D Miller, Jacqueline Castillo, Brandy Boeger, Susan Vidaurre, Stefanie Pieper, Cecile Nguyen, Duc Anh Thanh Huynh, Jessica Wooden, Amy Franklin, Karen Moody, Wenyaw Chan, Pamela S Hinds, Constance Johnson

Faculty, Staff and Student Publications

Background: Children undergoing cancer treatment experience a range of treatment-related toxicities that significantly affect quality of life and adherence to therapy. Current methods for symptom reporting rely heavily on clinician interpretation of caregiver or child verbal reports, which can result in incomplete or inaccurate records. The Pediatric Patient-Reported Outcomes version of the Common Terminology Criteria for Adverse Events (Pediatric PRO-CTCAE; National Cancer Institute) provides a validated mechanism for direct symptom reporting by children and caregivers, yet its traditional administration and preselection of questions limit the breadth of symptom capture.

Objective: This research aimed to co-design and conduct formative usability testing …

Deep Learning Compilers, Raffi Khatchadourian

Open Educational Resources

These lecture slides introduce deep learning compilers for a graduate compiler-construction course (CSc 81010). Building on the classical compiler pipeline, they show how modern machine-learning systems compile tensor programs: static tensor and type analysis (illustrated by a WALA/Ariadne-based refactoring of imperative TensorFlow code to graph mode), MLIR-based end-to-end compilation with IREE, and the PyTorch 2.x stack—TorchDynamo graph capture, AOTAutograd, PrimTorch operator decomposition, and TorchInductor lowering to Triton (GPU) and C++/OpenMP (CPU). The slides are a self-contained HTML (W3C Slidy) deck with editable Pandoc Markdown source. Part of a two-session unit on advanced compiler topics; see also "LLMs in Compiler Construction."

Effective Strategies Psychiatric Hospital Leaders Use To Retain Staff To Avoid Turnover Costs, Christian Azuka Obiajulu Ossai

Walden Dissertations and Doctoral Studies

No abstract provided.

Teachers’ Perspectives And Experiences On Using Assistive Technological Tools To Support Middle School Students With Dyslexia, Crystal Courtner

Walden Dissertations and Doctoral Studies

No abstract provided.

The Impact Of Nurse-Led Universal Depression And Suicide Risk Screening On Adolescent Mental Health Outcomes In Pediatric Primary Care, Malu-Kanoa Hewitt, Briana Morris, Dolly Ukpong, Lula Teklehaimanot, Preet Kamal Singh, Latasha Scott, Charity Msamalia Chimwala-Selico

General Submissions: Clinical Settings Materials

Background: Adolescent depression and suicide are critical public health concerns in the United States. Approximately 20% of youth aged 12–17 experience a major depressive episode annually, yet fewer than half receive treatment (NIMH, 2023). Suicide is a leading cause of death among adolescents and young adults (CDC, 2023). The U.S. Preventive Services Task Force (USPSTF) recommends screening for major depressive disorder (MDD) in adolescents aged 12–18 when adequate systems are in place for diagnosis, treatment, and follow-up, but concludes that evidence is insufficient to recommend routine suicide risk screening in children and adolescents (USPSTF, 2022).

Purpose: This literature review evaluates …

Can Architecture Save The World?, Stella Majewsky

Bachelor of Architecture Theses - 5th Year

The Okefenokee Swamp in Georgia has been under ongoing threat from mining. It sits at the border between Georgia and Florida in an area with child poverty rates up to 52 %.Heavy reliant on the timber industry, the region has suffered ecologically through hurricanes, mill closures and various other economic forces. The thesis proposes an architectural intervention in the Stephen Foster State Park in the Okefenokee. The objective is to develop an architecture that will help to protect the swamp; an architecture which invites the visitor to follow a trail into the swamp, to learn about the unique landscape, and …

Reclaiming Civic Space: Designing A Public Space For Political Engagement, Joiya Nguyen

Bachelor of Architecture Theses - 5th Year

According to a 2018 survey of the United States, loneliness has reached generational highs, particularly among those who substitute social media for in-person social relationships — from dating to political engagement. Despite this knowledge, digital interaction continues to displace physical community. The root of this turn to the digital is the lack of adequate public spaces. This project investigates how the built environment can reclaim civic spaces by offering meaningful, in-person alternatives to digital interaction.

Drawing on Henri Lefebvre's Right to the City and Anthony Vidler's writing on occupied spaces, alongside an analysis of historical civic precedents, this research maps …

Economic Survival And Chosen Kinship: Analyzing Intersectionality’S Role In Reframing Trans Representation In Tangerine, Lydia Britton '27

Student Research

Transgender representation in mainstream media has grown in recent years. However, these portrayals are often hegemonic, clinging to a traditional worldview. Depictions of trans characters prioritize Whiteness, higher socioeconomic status, and transitions that adhere to the binary. Additionally, transgender characters often have access to gender-affirming care and are supported by their families throughout their transition (Mocarski et al., 2019). Research on the media representations of transgender and gender diverse (TGD) individuals points out how these portrayals reinforce ideals surrounding transnormativity, or the idea that trans people’s identities and experiences must be applied to the dominant binary and medicalized framework (Bradford …

Λ-Fold Near-Factorizations Of Groups, Donald L. Kreher, Shuxing Li, Douglas R. Stinson

Michigan Tech Publications

We initiate the study of λ-fold near-factorizations of groups with λ>1. While λ-fold near-factorizations of groups with λ=1 have been studied in numerous papers, this is the first detailed treatment for λ>1. We establish fundamental properties of λ-fold near-factorizations and introduce the notion of equivalence. We prove various necessary conditions of λ-fold near-factorizations, including upper bounds on λ. We present three constructions of infinite families of λ-fold near-factorizations, highlighting the characterization of two subfamilies of λ-fold near-factorizations. We discuss a computational approach to λ-fold near-factorizations and tabulate computational results for abelian groups of small order.

Kattam Choreography- A Facade Of The Virgin Islands, Kiyani J.M. Ottley

Bachelor of Architecture Theses - 5th Year

Kattam Choreography reimagines a historic building in Charlotte Amalie, St. Thomas, USVI as a vibrant cultural hub that celebrates dance, memory, and commerce. Rooted in the embodied traditions of the qudrille folk dance, this project explores adaptive reuse as a performtive act—where architecture becomes a living archive of movement and heritage.

The design treats the building’s layered history not as a static artifact, but as a choreographic score. Quadrille’s spatial logic—its symmetry, rhythm, and communal gestures—informs circulation, program, and atmosphere. The building unfolds as a triptych: a dance pavilion, multi-purpose educational spaces, and a gift shop. Each element responds to …

Constructing Atmosphere The Use Of Light And Water As The Generators Of Architectural Atmosphere, Victoria A. Cioffi

Bachelor of Architecture Theses - 5th Year

What if the spaces we inhabit are no longer felt, only seen? In contemporary architecture, many buildings are designed for visual impact rather than human experience, often resulting in environments that feel emotionally detached. This thesis asks a central question: have buildings lost their soul? It proposes that atmosphere, understood as the sensory and emotional quality of space, is essential to restoring meaning and connection within architecture.

Drawing from the work of Peter Zumthor, this research explores how architecture can move beyond visual form to engage the body through environmental conditions. The study focuses on light, shadow, and water as …

Resurrecting The Romani Presence - Restoring Cultural Memory In Triana Seville, Jesus A. Sanchez

Bachelor of Architecture Theses - 5th Year

In an era of placeless architecture and fragmented civic identity, this thesis investigates how design can cultivate belonging through cultural and historical meaning. It examines the disjunction between spatial function and symbolic resonance in contemporary civic institutions, proposing a framework for architectural memory — a system of strategies that translate narrative, context, and collective history into spatial experience. Through precedent studies and design research, the project explores how rootedness can be achieved through materiality, sequencing, and light, transforming civic space into a vessel of memory and participation. The design proposal, a Romani Museum in Triana, Seville, situates architecture within …

The Use Of Tactile Stimulations To Mitigate Somatic Anxiety Responses: A Pilot Study, Abigail C. Robbins

Masters Theses

Anxiety is the body’s response to detected danger or stress. Physiological responses include shallow breathing, increased heart rate, sweating, shaking, and muscle tension. Roughly 33.7% of the population experiences anxiety, with approximately 40 million adults in the United States being affected by the disorder. Anxiety can create severe personal, social, and economic burdens. Traditional treatments of anxiety disorders such as medication and psychotherapy can be effective, but present multiple barriers such as cost, accessibility, and side effects. As a result, there is a growing industry for non-invasive, low-cost solutions that can help individuals regulate their physiological anxiety responses and reduce …

Glp-1 Receptor Agonists And Disordered Eating: Clinical Indicators And Patient Narratives, Samantha E. Schulz

Masters Theses

Introduction: The use of the medication, GLP-1 receptor agonist (GLP-1 RA), for weight loss has increased exponentially in the United States over the past decade. The continuing rise in demand for the use of GLP-1 RAs for weight loss justifies the need to better understand the physical and psychological effects that can occur with significant weight loss. By combining a standardized screening tool for eating disorder (ED) risk with narratives from patients undergoing GLP-1 RA treatment for weight loss, this study examines associations between GLP-1 RA use patterns and risk of ED and explores patient experiences, including the role of …

Experimental Measurements Of The Forces Acting On A Submerged Beam Using High-Speed Videography, Madelyn Burrell

Masters Theses

The interaction of structures and fluids is highly relevant in many fields but difficult to accurately and reliably characterize. This study demonstrates a novel method of simplifying such problems by analyzing the structural deformations directly, without needing to explicitly solve for the fluid aspect. Six cantilever beams of varying properties were submerged in still water and released from an initial deflection at the free end: the cases consisted of three beam shapes (one of uniform width, one with a narrower free end, and one with a wider free end), with an end mass attached or detached. High-speed videography was utilized …

Law Enforcement Perceptions And Lived Experiences Concerning Homelessness, Pedro Osbaldo Preciado

Walden Dissertations and Doctoral Studies

No abstract provided.

Perceptions Of Music Educators On Their Preparedness To Implement Information And Communication Technology In Online Music Education, Marcia James

Walden Dissertations and Doctoral Studies

No abstract provided.

Reducing Burnout Among Psychiatric Practitioners And Therapists, Sarah Lemaine

Walden Dissertations and Doctoral Studies

No abstract provided.

Apoe Ε2 Potential Protection Against Long-Term Consequences Of Traumatic Brain Injury, Rebecca Faith Mesidort

Graduate Student Dissertations, Theses, Capstones, and Portfolios

Traumatic brain injury (TBI) can alter the quality of life, often resulting in cognitive decline, neurodegeneration, or death. There have been no biological advances to resolve the long-term consequences of TBI. The APOE ε2 gene is well known as a neuroprotectant against neurodegenerative diseases such as Alzheimer’s disease and Parkinson’s disease. However, the biological mechanisms of how APOE ε2 protects against neurodegeneration are unknown. The purpose of this study is to investigate APOE ε2’s response to an environmental stimulus that leads to neurodegeneration, TBI, and further investigate APOE ε2’s biological mechanisms. After inflicting blunt force trauma to our model organism, …

Modeling Velocity Distributions Of Interstellar Neutral Hydrogen In The Heliosphere, Lucas Robert Dyke

Dartmouth College Ph.D Dissertations

As interstellar neutral hydrogen (ISN H) is the most abundant neutral element in the helio- sphere, the region within which the solar wind interacts with the portion of the interstellar medium through which our solar system moves through, it is integral that we aim to under- stand its many properties and interactions within this region. This work details the synthesis and use of a model of ISN H, using trajectory methods to backtrace from a target point at a radial distance of 1 au where explorer probes like Interstellar Boundary Explorer (IBEX) and Interstellar Mapping and Acceleration Probe (IMAP) reside. …

A Review Of Magnesium-Based Stents: Manufacturing Strategies And Future Trends, Amir Motaharinia, Amir Sanati Nezhad, Jeremy Goldman, H. R. Bakhsheshi-Rad, J. Drelich

Michigan Tech Publications

Coronary artery disease is often treated with vascular stents to restore the blood flow. Recently, there has been growing interest in biodegradable metal stents, especially those made from magnesium (Mg). This review starts by explaining the complex pathophysiology of atherosclerosis and the current treatment options. It then discusses stents, including their potential benefits, capabilities, and limitations, as they represent the gold standard for percutaneous coronary intervention in treating atherosclerosis. Given the vital role of stents, we provide a thorough review of the manufacturing techniques involved, such as wire forming, subtractive manufacturing, and additive manufacturing, with a specific focus on stents …

Llms In Compiler Construction, Raffi Khatchadourian

Open Educational Resources

These lecture slides survey the use of large language models (LLMs) in compiler construction for a graduate compiler course (CSc 81010). They situate LLMs across the compiler pipeline and examine representative work: foundation models trained on LLVM IR and assembly (Meta's LLM Compiler), LLM-driven code optimization, binary decompilation (LLM4Decompile), and LLM-assisted automated refactoring—alongside the challenges of applying probabilistic models to tasks that demand correctness. The slides are a self-contained HTML (W3C Slidy) deck with editable Pandoc Markdown source. Part of a two-session unit on advanced compiler topics; see also "Deep Learning Compilers."

2026 Phi Beta Kappa Induction Ceremony Program, Phi Beta Kappa, Psi Of California Chapter At Chapman University

Phi Beta Kappa Induction Ceremony Programs

The 2026 Induction Ceremony for the Psi of Chapter California was held on May 12, 2026 at the Hilbert Museum of California Art at Chapman University. In this ceremony, 27 outstanding students and one honorary member were inducted into Phi Beta Kappa.

Please click here to view photos from the ceremony.

Automation, Migration, And Development: Geography Of Job Precarity In South Asia And North Africa, Keshav Bhattarai, Ambika P. Adhikari

Himalayan Research Papers Archive

This article examines how accelerating automation and the adoption of artificial intelligence (AI) in advanced economies reshape labor markets across the Global South through interconnected channels of production, migration, and remittances. Drawing on the theories and practices of economic geography, labor economics, and development studies, the analysis conceptualizes automation as a transnational shock that contracts demand for migrant labor while simultaneously amplifying employment precarity in labor-surplus economies. The article advances a geographically grounded framework linking technology adoption in core industries with labor displacement, youth unemployment, and urban labor saturation in South Asia and North Africa. It further highlights the macroeconomic …

Built For The Moment: Creating Temporary Hotel Architecture With Prefabrication For Transit-Oriented Development Along Marta Stations, Joshua D. Aicher

Bachelor of Architecture Theses - 5th Year

This thesis explores an architectural approach to addressing temporary population increases caused by large sporting events through flexible, prefabricated structures that adapt to varying sites and programmatic needs. The project is situated in the context of the 2026 FIFA World Cup in the United States, where host cities face significant pressure to accommodate short-term population surges. Typically, cities invest heavily in roads, transit, and hotels to support these events which are then abandoned or underutilized after events. While cities such as London 2012 Olympic Games and Tokyo 2020 Olympic Games leveraged existing, mature transit networks to absorb this increased demand, …

Placemaking On Peachtree: Breathing Life In To Downtown Atlanta’S Outdoor Environment Through Wellbeing-Centric Design, Rachel Pickert

Bachelor of Architecture Theses - 5th Year

Why do outdoor public spaces in Atlanta not prioritize pedestrian well-being by providing comfort, safety, and service to their daily life? The built environment is a key determinant of overall well-being through the opportunity for social interaction, stimulation, safety, comfort, and a sense of belonging. The vehicular-centric design of Downtown Atlanta has resulted in pedestrians seeking comfort away from the ground level using viaducts, subterrain transit, and sky bridges. This historic removal of pedestrians from the streets of Atlanta has resulted in un-activated outdoor public spaces which do not fulfill the basic needs for pedestrian wellbeing. This thesis uses existing …

Domestic Remix: Rethinking Home When Everything Happens Everywhere All At Once, Erika Louise Morales

Bachelor of Architecture Theses - 5th Year

With the cost of living rising, Americans are gravitating towards a living arrangement that may seem unconventional by local standards, but is common throughout the world: multigenerational households. This shift signals a growing openness to shared domesticity and a more collective way of living. Traditionally, Americans, like many Western cultures, are perceived to be more individualistic, whereas multigenerational living is often associated with more traditionally collectivist societies in the East. Yet, as social and economic pressures rise, Americans are reconsidering what “home” means to them, not only in terms of their individual space, but in terms of how their day …