Digital Commons Network^™

The Immune System And Metabolic Products In Epilepsy And Glioma-Associated Epilepsy: Emerging Therapeutic Directions, Craig M Horbinski, Jessica W Templer, Joshua M Rosenow, Timothy L Sita, Charles D James, Benjamin Deneen, Stephen D Miller, Amy B Heimberger

Faculty, Staff and Students Publications

Epilepsy has a profound impact on quality of life. Despite the development of new antiseizure medications (ASMs), approximately one-third of affected patients have drug-refractory epilepsy and are nonresponsive to medical treatment. Nearly all currently approved ASMs target neuronal activity through ion channel modulation. Recent human and animal model studies have implicated new immunotherapeutic and metabolomic approaches that may benefit patients with epilepsy. In this Review, we detail the proinflammatory immune landscape of epilepsy and contrast this with the immunosuppressive microenvironment in patients with glioma-related epilepsy. In the tumor setting, excessive neuronal activity facilitates immunosuppression, thereby contributing to subsequent glioma progression. …

Differences In Out-Of-School Suspensions Between Black And White High School Students When Controlling For Student Factors, School Factors, And Delinquency, Steven Craig Davidson

Doctoral Dissertations and Projects

This quantitative, correlational study aims to determine how accurately out-of-school suspensions can be predicted from a linear combination of student delinquency, in-school delinquency, and prior suspensions for Black and White high school students. Further, a causal-comparative design is used to determine if there is a statically significant difference in out-of-school suspensions between Black and White high school students when controlling for student factors, school factors, and student delinquency factors. The study consists of five guiding theories that inform two general hypotheses. The first hypothesis, referred to as the differential selection hypothesis, is guided by critical race theory (CRT) and implicit …

Development Of A Suspended Aerobic Membrane Bioreactor (Sambr) For Sustainable Wastewater Treatment On Early Planetary Bases, Talon James Bullard

USF Tampa Graduate Theses and Dissertations

Environmental Control and Life Support Systems (ECLSS) ideally should treat all “waste” streams for recovery in a sustainable and near closed-loop manner. This will be critical for Partial Gravity Habitats (PGH) and Early Planetary Bases (EPB) that will be established on the Moon and Mars due to the lack of readily available resources. Currently, the Water Recovery System (WRS), onboard the International Space Station (ISS), recovers and purifies water from urine and graywater. While efficient, this system is not optimized for future missions and utilizes physical-chemical technologies that operate with single-use and hazardous consumables. In response to the lack of …

Arab Journalists Have No Place: Authorities Use Digital Surveillance To Control Investigative Reporting, Miral Sabry Alashry

Faculty Journal Articles

The purpose of this study was to investigate the extent of digital surveillance by Arab authorities, who face risks and threats of surveillance, and how journalists seeking press freedom use tools and techniques to communicate securely, such as open source in journalism. These journalists share and rely heavily on an opensource data ideology. With novel methods and tools, they integrate a new set of actors, competencies, and technologies into journalistic practice, renegotiating and transcending professional boundaries. The methodology of the study was based on in-depth interviews from Egypt, Yemen, Syria, Lebanon, Jordan, Libya, and Tunisia with a selection of journalists …

Exploring The Relationship Between Staffing And Long-Term Care Worker Mental Health, Matthew R. Trombley

Doctoral Dissertations and Projects

This research delves into the relationship between staffing levels during a crisis in the healthcare workforce and the mental well-being of long-term care workers, with a specific focus on variables such as burnout, compassion fatigue, and compassion satisfaction. With increasing workforce shortages, the attention to providing quality care during this tumultuous period has become increasingly urgent. There has been scarce empirical research that has explicitly sought to comprehend the connection between staffing levels and the mental health of long-term care professionals. This study was designed as a non-experimental, quantitative correlational investigation, aiming to understand the intricate dynamics between patient-to-staff ratios …

Burnout Triggers In The Novice Registered Nurse, Sharon K. Nguyen

Doctoral Dissertations and Projects

Nurse burnout has been strongly associated with decreased patient satisfaction and reduced retention rates in the novice registered nurse. This phenomenon is exacerbating the already rising global nursing shortage. A strong correlation is established between novice registered nurses who endure repeated or multiple triggers, such as unsafe staffing ratios, inadequate preceptorship, and ineffective leadership to those who succumb to burnout. Burnout is a significant problem in the United States, impacting how healthcare is perceived by the public. In 2019 there were more than six million nurses, making up the largest segment of the healthcare population and directly affecting the safety …

The Effects Of Social Gratitude On Anxiety, Depression, And Persistence To Graduate Among College Students, Terrie L. Hilbun

Doctoral Dissertations and Projects

Anxiety and depression have become increasingly prevalent among college students, leading to negative consequences such as decreased persistence to graduate. This study’s goal was to research the effects of a two-week gratitude intervention on attitude health, focusing on gratitude, depression, anxiety, and persistence of college students. The participants were drawn from a convenience sample of community college students located in northeast Alabama. A single pre-and post-test design was utilized, to compare the effects of a social gratitude intervention on gratitude, anxiety, depression, and persistence. A total of 25 volunteers, aged 18 or older, participated. It was hypothesized that there would …

Philosophies Of Empirical And Habitual Teaching: Healthy Vocal Methodologies In Higher Education For The Twenty-First Century, Katie Denise Osuamkpe

Doctoral Dissertations and Projects

Despite research done on healthy vocal methodologies, there are continuous changes in how best to prepare collegiate music students, relating to their emotional health through empirical and habitual teachings. This study will show how healthy vocal methodologies can influence higher education vocal students of the twenty-first century. This qualitative study can build a bridge to related topics in an exploratory framework with perspectives on: Dr. William Hettler’s Emotional Well-Being and its seven dimensions, Jean Piaget's Cognitive Construction Theory, Peter Salovey and John Mayer's Emotional Intelligence Theory, Daniel Goleman’s Social Emotional Learning Methodology, Susan Brookhart’s “Classroometrics” Theory, Howard Gardner’s Theory of …

The Mental Health Effects Of Vicarious Trauma, Moral Injury, And Positive Religious Coping With Canine Comfort Handlers, Terri Jeanne O'Brien-Cross

Doctoral Dissertations and Projects

The intention of this study was to examine whether positive religious coping buffered the mental health effects of vicarious trauma and moral injuries in canine comfort handlers. By examining whether positive religious coping would reduce symptoms of posttraumatic stress disorder (PTSD), a better understanding of the mental, emotional, and spiritual effects of volunteer handlers was discovered. Handlers work throughout their communities and deploy to crisis events such as mass shootings and natural disasters. By partnering with highly trained canines, they provide support and comfort to those in need. During these interactions, handlers are often exposed to traumatic situations and may …

Age-Related Differences In Motor Skill Transfer With Brief Memory Reactivation, Kylie B Tomlin, Brian P Johnson, Kelly P Westlake

2020-Current year OA Pubs

Motor memories can be strengthened through online practice and offline consolidation. Offline consolidation involves the stabilization of memory traces in post-practice periods. Following initial consolidation of a motor memory, subsequent practice of the motor skill can lead to reactivation and reconsolidation of the memory trace. The length of motor memory reactivation may influence motor learning outcomes; for example, brief, as opposed to long, practice of a previously learned motor skill appears to optimize intermanual transfer in healthy young adults. However, the influence of aging on reactivation-based motor learning has been scarcely explored. Here, the effects of brief and long motor …

Light That Appears To Come From A Source That Does Not Exist, Itamar Stern, Yakov Bloch, Einav Grynszpan, Merav Kahn, Yakir Aharonov, Justin Dressel, Eliahu Cohen, John C. Howell

Mathematics, Physics, and Computer Science Faculty Articles and Research

Superoscillatory, band-limited functions oscillate faster than their fastest Fourier component. Superoscillations have been intensively explored recently as they give rise to many out-of-the-spectrum phenomena entailing both fundamental and applied significance. We experimentally demonstrate a form of superoscillations which is manifested by light apparently coming from a source located far away from the actual one. These superoscillations are sensed through sharp transverse shifts in the local wave vector at the minima of a pinhole diffraction pattern. We call this phenomenon “optical ventriloquism.”

Cell Membrane-Anchored And Tumor-Targeted Il-12 T-Cell Therapy Destroys Cancer-Associated Fibroblasts And Disrupts Extracellular Matrix In Heterogenous Osteosarcoma Xenograft Models, Jiemiao Hu, Alexander J Lazar, Davis Ingram, Wei-Lien Wang, Wendong Zhang, Dristhi Ragoonanan, Xueqing Xia, Kris Mahadeo, Richard Gorlick, Shulin Li

Faculty, Staff and Student Publications

Background: The extracellular matrix (ECM) and cancer-associated fibroblasts (CAFs) play major roles in tumor progression, metastasis, and the poor response of many solid tumors to immunotherapy. CAF-targeted chimeric antigen receptor-T cell therapy cannot infiltrate ECM-rich tumors such as osteosarcoma.

Method: In this study, we used RNA sequencing to assess whether the recently invented membrane-anchored and tumor-targeted IL-12-armed (attIL12) T cells, which bind cell-surface vimentin (CSV) on tumor cells, could destroy CAFs to disrupt the ECM. We established an in vitro model of the interaction between osteosarcoma CAFs and attIL12-T cells to uncover the underlying mechanism by which attIL12-T cells penetrate …

Toward Standardization, Harmonization, And Integration Of Social Determinants Of Health Data: A Texas Clinical And Translational Science Award Institutions Collaboration, Catherine K Craven, Linda Highfield, Mujeeb Basit, Elmer V Bernstam, Byeong Yeob Choi, Jonathan A Gelfond, Vaishnavi Kannan, Paula K Shireman, Heidi Spratt, Kayla J Torres Morales, Chen-Pin Wang, Zhan Wang, Meredith N Zozus, Edward C Sankary, Susanne Schmidt

Faculty, Staff and Student Publications

INTRODUCTION: The focus on social determinants of health (SDOH) and their impact on health outcomes is evident in U.S. federal actions by Centers for Medicare & Medicaid Services and Office of National Coordinator for Health Information Technology. The disproportionate impact of COVID-19 on minorities and communities of color heightened awareness of health inequities and the need for more robust SDOH data collection. Four Clinical and Translational Science Award (CTSA) hubs comprising the Texas Regional CTSA Consortium (TRCC) undertook an inventory to understand what contextual-level SDOH datasets are offered centrally and which individual-level SDOH are collected in structured fields in each …

Steeper Size Spectra With Decreasing Phytoplankton Biomass Indicate Strong Trophic Amplification And Future Fish Declines, Angus Atkinson, Axel G. Rossberg, Ursula Gaedke, Gary Sprules, Ryan F. Heneghan, Stratos Batziakas, Maria Grigoratou, Elaine Fileman, Katrin Schmidt, Constantin Frangoulis

School of Geography, Earth and Environmental Sciences

Under climate change, model ensembles suggest that declines in phytoplankton biomass amplify into greater reductions at higher trophic levels, with serious implications for fisheries and carbon storage. However, the extent and mechanisms of this trophic amplification vary greatly among models, and validation is problematic. In situ size spectra offer a novel alternative, comparing biomass of small and larger organisms to quantify the net efficiency of energy transfer through natural food webs that are already challenged with multiple climate change stressors. Our global compilation of pelagic size spectrum slopes supports trophic amplification empirically, independently from model simulations. Thus, even a modest …

Prediction Of Hydrogel Degradation Time Based On Central Composite Design, Manlai Zhang, Xiaohui Li

Faculty, Staff and Student Publications

In this study, a self-degrading hydrogel was formed by free-radical-initiated copolymerization, which can be used for oil and gas well strip pressure operations. Fourier transform infrared spectroscopy (FTIR), nuclear magnetic resonance (1H NMR), scanning electron microscopy (SEM), and thermogravimetry-mass spectrometry (TGA-MS) were used to study the reaction mechanism as well as the microstructure of the gels. Then, the effects of the four factors and their interactions on gel degradation time were determined by central composite design (CCD). Then, the effects of copolymer concentration, cross-linker, initiator, and reaction temperature and their interactions on gel degradation time were determined by central composite …

Analisis Butir Soal Okupasi Terapi Pada Pediatri Menggunakan Software Klasika Dengan Pendekatan Classical Test Theory (Ctt), Reza Nur Arsyi, Hermito Gideon

Jurnal Vokasi Indonesia

Penelitian ini bertujuan untuk mendeskripsikan hasil analisis kualitas soal yang ada pada soal okupasi terapi pediatri dibutuhkan karena sebagai salah satu bahan evaluasi pengajaran dan evaluasi terhadap pengetahuan yang dimiliki oleh mahasiswa. Penelitian ini merupakan penelitian deskriptif dengan pendekatan kuantitatif. Ujian terdiri dari 31 item yang diujikan pada 60 mahasiswa yang telah mendapatkan mata kuliah Okupasi Terapi pada pediatri, Evaluasi tersebut dianalisis dengan pendekatan classical test theory menggunakan software klasika. Hasil yang diperoleh dari penelitian klasika diperoleh nilai SEM 2,123, alpha 0,635, mean biserial 0,428, daya pembeda pada item diterima sebanyak 20, 4 item perlu direvisi/dicek dan 7 item ditolak. …

Hubungan Antara Fear Of Falling Dengan Aktivitas Fisik Pada Lansia Di Panti Jompo, Inez Deviantika, Farahdina Bachtiar, Ika Fitri Wulan Dhari, Andy Sirada

Jurnal Vokasi Indonesia

Pada lanjut usia (lansia), terjadinya perubahan fisik akan mempengaruhi proses aktivitas fisiknya. Salah satu faktor yang menjadi faktor terhambatnya aktivitas fisik adalah rasa takut jatuh, dimana hal ini dapat timbul dari pengalaman yang dirasakan lansia. Lansia akan menghindari aktivitas yang menimbulkan risiko jatuh bagi dirinya. Penelitian ini bertujuan untuk mengetahui hubungan antara fear of falling dan aktivitas fisik pada lansia. Penelitian ini menggunakan metode cross sectional dengan pendekatan korelasi di Panti Jompo Hajjah Andi Hasmah Noor Jakarta. Alat ukur yang digunakan dalam penelitian ini adalah Physical Activities Scale For Elderly (PASE-I) dan Modified Falls Efficacy Indonesian Scale (FES-I). Berdasarkan hasil …

Comparing The Effectiveness Of Static And Dynamic Audiovisual In An Additional Geography Lesson In One Pathway College In Jakarta, Erni Adelina, Peny Meliaty Hutabarat

Jurnal Vokasi Indonesia

Students are now used to using audiovisual platforms to learn as they once were forced to adapt to this type of learning due to face-to-face lessons were impossible at that time because of the pandemic. Audiovisual learning resources came out sporadically to accommodate the needs of study at home or anywhere possible. The static audiovisual (enhanced podcast) and dynamic audiovisual (video) are two types of virtual platforms educators continuously harness to support their lesson teachings even though the face-to-face meetings have been allowed gradually. However, there are not many studies conducted to analyze whether one type is more effective in …

Impact Of Weather Factors On Airport Arrival Rates: Application Of Machine Learning In Air Transportation, Robert W. Maxson, Dothang Truong, Woojin Choi

Journal of Aviation Technology and Engineering

Weather is responsible for approximately 70% of air transportation delays in the National Airspace System, and delays resulting from convective weather alone cost airlines and passengers millions of dollars each year due to delays that could be avoided. This research sought to establish relationships between environmental variables and airport efficiency estimates by data mining archived weather and airport performance data at ten geographically and climatologically different airports. Several meaningful relationships were discovered from six out of ten airports using various machine learning methods within an overarching data mining protocol, and the developed models were tested using historical data.

Exploring The Role Of Physical Activity Influencing Emotional Regulation And Mental Health In Adolescents, Alejandro G. Martinez, Lindsay Gietzen, Valerie F. Mcdaniel

Pacific Journal of Health

This research paper explores the intricate relationship between physical activity, emotional regulation, and mental health in adolescents through an in-depth content analysis grounded in catharsis theory and the transactional theory of stress and coping. It underscores physical activity as the best practice for adolescents to manage emotions and mental health, identifying key themes that highlight its role in enhancing emotional regulation skills and reducing anger, anxiety, and depression. The catharsis theory suggests physical activity releases negative emotions, while the transactional theory explores how adolescents perceive and respond to stressors. Emphasizing the positive impact of physical activity on emotional regulation and …

From Panels To Shelves: The Evolving Intersection Of Comics And Italian Libraries. History, Issues, Perspectives, Andrea Tosti

SANE journal: Sequential Art Narrative in Education

Despite comics' popularity and cultural significance in Italy, its integration into Italian libraries has been slow, problematic, and uneven. This is reflected in the scarcity of academic research on the topic, which demands further in-depth exploration.

In the context of Italian libraries, characterized by chronic underfunding and staffing shortages, comics might be perceived as a low priority. However, as essential cultural institutions, libraries must strive to reflect both the contemporary era and the evolving reading habits of their audience. Comics, in this regard, could prove to be – and in part already are – a critical resource, a 'booster' for …

Developing And Sustaining A Graphic Scholarship Collection For Academic Libraries, Stewart Brower, Toni Hoberecht, Zane Ratcliffe, Bethie Seay

SANE journal: Sequential Art Narrative in Education

In early 2021, the Schusterman Library at the University of Oklahoma-Tulsa satellite campus took a new step towards building a culture of interest by creating the Graphic Scholarship Collection. This new endeavor is a curated collection of graphic novels, primarily non-fiction, aligned with the academic programs on campus, as well as promoting University initiatives in diversity, equity, and inclusion. A new organizational structure for the collection materials and their circulation metrics will be examined in detail. There will also be consideration of the challenges of selection and acquisition by a mixed team of selectors, some of whom have no experience …

Lanthorn, Vol. 58, No. 10, January 8, 2024, Grand Valley State University

Volume 58, August 7, 2023 - April 15, 2024

Lanthorn is Grand Valley State's student newspaper, published from 1968 to the present. Issue 9 is currently missing from our collection.

The Utah Statesman, January 8, 2024, Utah State University

The Utah Statesman

Weekly student newspaper of Utah State University in Logan.

Faculty Senate Monthly Packet January 2024, Portland State University Faculty Senate

Faculty Senate Monthly Packets

The January 8, 2024 monthly packet includes the January agenda, appendices, and the Faculty Senate minutes and attachments from the meeting held January 8, 2024.

Stevens-Johnson Syndrome From Combined Allopurinol And Angiotensin-Converting Enzyme Inhibitors: A Narrative Review, Isabella M. Fabian, Kirsten Maddox, Cameron Robicheaux, Rahib K. Islam, Ahmed Anwar, Bradley Dorius, Christopher L. Robinson, Adam M. Kaye, Giustino Varrassi, Shahab Ahmadzadeh, Sahar Shekoohi, Alan D. Kaye

School of Pharmacy Faculty Articles

Stevens-Johnson syndrome (SJS) is a severe and potentially debilitating skin reaction frequently related to medication use. Allopurinol and angiotensin-converting enzyme (ACE) inhibitors are commonly prescribed medications for prevalent health conditions worldwide, and their interaction associated with SJS warrants further investigation. A comprehensive literature search was performed to investigate cases as studies related to SJS occurring in patients with concomitant use of allopurinol and ACE inhibitors. We identified case reports and studies detailing hypersensitivity reactions, including SJS, attributed to a combination of allopurinol and ACE inhibitors. Despite the drug-drug interactions or lack thereof seen in patient populations, there is no definitive …

General Education Subcommittee Minutes 12-7-2023, Utah State University

Educational Policies Committee

• Call to Order - Matt Sanders
• Approval of Minutes- November2, 2023
• Course Approvals/Removals/Syllabi Approvals
• New Business
• Additional Items
• Adjourn: 9:26

Caste-Ethnicity Based Disparities In The Labor Market: Evidence From Panel Household Surveys In Nepal, Rajendra Dulal, Shankar Ghimire, Kul Kapri

Pennsylvania Economic Review

This paper examines labor market disparities across various caste-ethnic groups in Nepal using the 2004 and 2011 Nepal Living Standards Survey data. We study annual wage and salary employment to identify the disparities at both the individual and group levels. First, we use panel regression to capture the disparities in wage and employment and then employ the Blinder-Oaxaca decomposition method to identify the determinants of these disparities across various caste-ethnic groups. The results show that individual, household, and caste-ethnicity specific factors are all critical determinants of labor market outcomes. The results indicate education as a key contributor to employment disparities …

Strategies And Resources For Integrating Technology Into The Secondary Education World Language Classroom, Angelina M. Bauer

Masters Projects

This document is a research-based project that includes a reference manual of strategies for technology integration in the World Language curriculum, as well as an example lesson plan that implements many of the strategies. Many of the strategies and examples can be adapted to fit multiple subject areas. The theoretical framework upon which the project is constructed is a combination of TPACK and several of Stephen Krashen's Theories of Second Language Acquisition.

Episode 7: Strange Bedfellows, Sara Gras

Season 01

In this episode I explore the various factions who, despite their different general ideologies, have united in advocating for the exclusion of trans kids from sports. My guests and I discuss why this presents such a challenge when working to educate and advocate around this issue. I also provide some additional details on one of the largest and most powerful organizations supporting exclusion.

Erin Buzuvis (Faculty Profile)
Associate Dean for Academic Affairs and Professor of Law, Western New England School of Law

Kurt Weaver
Executive Director, You Can Play Project

Shira Berkowitz (Organizational Bio)
Senior Director …