Digital Commons Network^™

Analysis Of Effect Of Grouting Micro⁃Pile Strengthening Subgrade Based On Heterogeneous Layer Model, Zhou Ke, Lei Jinsheng, Liu Jinxin, Liu Wanchun, Shi Zhiqiang, Dang Runmeng

Journal of China & Foreign Highway

In view of subgrade sedimentation and other hazard control problems of road subgrade diseases, this paper considered the spatial heterogeneity of soil parameters of subgrade with diseases and analyzed the characteristics of grouting micro⁃pile strengthening subgrade. Meanwhile, based on the stochastic fractal search algorithm, it generated a random distribution profile of voidage, elastic modulus, and permeability coefficient, built a heterogeneous formation model, and simulated grouting diffusion in the subgrade. According to the calculation results of grouting diffusion, the effect of grouting micro-piles on strengthening subgrade was analyzed. The results show that due to the uneven distribution of geophysical parameters, the …

Numerical Study On Effect Of Heterogenicity On Micro⁃Cracking Behavior Of Cement⁃Stabilized Macadam Material, Dong Qiao, Yuan Jiawei, Zhao Xiaokang, Chen Xueqin

Journal of China & Foreign Highway

To investigate the effect of heterogeneity of cement mortar on the micro-cracking behavior of cement-stabilized macadam (CSM) material, this paper built a circular aggregate micro-fracture model based on the finite element method (FEM). Meanwhile, the micro-cracking behavior of the material was simulated by embedding a zero-thickness cohesive element with a bilinear cohesive zone model, and the material random field with Weibull distribution was introduced to characterize the heterogeneity characteristics of the mortar matrix and interface transition zone (ITZ). Based on virtual semicircular bending (SCB) tests, this paper simulated the micro-cracking process and analyzed the influence of material homogeneity on the …

Soil Arching Effect Of Pile Supported Emban Kmentand Evolution Law Of Bearing Characteristics, Huang Zebin, Xie Zhiwei, Lu Jun, Liu Xianlin, Lv Xilin

Journal of China & Foreign Highway

The pile-supported embankment is widely used for subgrade settlement control in soft soil areas. Analyzing the soil arch effect of the embankment is the key to obtaining its bearing and deformation characteristics. Physical model tests of the soil arch effect and three-dimensional elastoplastic finite element numerical simulation of pile-supported embankment were carried out to study the soil arch formation process and bearing characteristics in embankment under the condition of differential settlement of pile and soil. The results show that with the increase in the differential settlement of pile and soil, the stress distribution in the embankment changes constantly, and the …

Study On Mix Design And Performance Of Cement Stabilized Coral Reef Mixture, Fan Xueyong, Xu Gang, Ma Qiang

Journal of China & Foreign Highway

The dredging process of harbor ponds will produce a large number of coral reef rocks. In order to reduce the impact of stone mining on the natural environment and improve the application of coral reef rock in the road base, this paper carried out the design of coral reef rock mixture grading according to Taylor n method, analyzed the impact of compaction process on the mixture grading through compaction test, and evaluated the degree of aggregate fragmentation with the breakage rate B5. The road performance of cement-stabilized coral reef rock mixture was studied by measuring the unconfined compressive strength, splitting …

2024 January 18, Faculty Senate Minutes, State University Of New York At Cortland

Minutes

Faculty Senate Minutes; 2024 January 18

SUNY Cortland Faculty Senate Committees Roster 2023-2024

Effects Of Organic Surface Contamination On The Mass Accommodation Coefficient Of Water: A Molecular Dynamics Study, Jordan Hartfield, Eric Bird, Zhi Liang

Mechanical and Aerospace Engineering Faculty Research & Creative Works

The mass accommodation coefficient (MAC), a parameter that quantifies the possibility of a phase change to occur at a liquid-vapor interface, can strongly affect the evaporation and condensation rates at a liquid surface. Due to the various challenges in experimental determination of the MAC, molecular dynamics (MD) simulations have been widely used to study the MAC on liquid surfaces with no impurities or contaminations. However, experimental studies show that airborne hydrocarbons from various sources can adsorb on liquid surfaces and alter the liquid surface properties. In this work, therefore, we study the effects of organic surface contamination, which is immiscible …

Spectator 2024-01-18, Editors Of The Spectator

The Spectator

No abstract provided.

Mo-Doped Titanate Nanofibers From Hydrothermal Syntheses For Improving Bone Scaffold, Yang Tian

Materials Science and Engineering Faculty Publications and Presentations

A longstanding interest in bone tissue engineering is the development of new bio- scaffolds that can be manufactured on a large scale with high throughput at low cost. Here, we report a low-cost and systematically optimized hydrothermal synthesis for producing Mo- doped potassium titanate nanofibers with high structural purity. This new nanosynthesis is based on bone tissue growth on an undoped titanate nanowires-entangled scaffold, as previously reported by our team. The morphological and structural characterization data suggest that the crystal structure of Mo-doped titanate nanofibers closely resembles that of the undoped ones. This resemblance is potentially valuable for assessing the …

Ypfs Lessons Learned Oral History Project: An Interview With Ignazio Visco, Ignazio Visco, Mercedes Cardona

Documents

No abstract provided.

Assessment Framework For Bim-Digital Twin Readiness In The Construction Industry, Ahmed Gouda Mohamed

Civil Engineering

This study introduces a pioneering structural equation modeling (SEM)-based framework to assess BIM-DT adoption readiness in sustainable construction. The research’s approach delves into the intricate correlation between key success factors (KSFs) and sustainable parameters (SPs), fostering BIM-DT deployment. This interdisciplinary perspective provides a holistic understanding of the impact of KSFs on BIM-DT adoption. The research aims to identify KSFs and parameters, prioritize their relative weights for BIM-DT implementation, analyze KSFs and SPs correlations, and offer practical insights into the findings. The results revealed the importance of sustainability considerations in BIM-DT adoption, with cost optimization and resource management playing pivotal roles. …

Alexander And The Roman Emperors, Sulochana Asirvatham

Department of Classics and General Humanities Faculty Scholarship and Creative Works

The Alexander most visible to us today is one who was created and recreated in the Roman period. While Alexander's presence in literature is strong enough that we can reasonably describe the trajectory of intellectual interest in Alexander during the Roman period, more difficult to pin down is the degree to which powerful Romans engaged in conscious imitatio or aemulatio Alexandri, which generally involves squaring literary hints with material evidence that does not always speak to us as directly as we would like it to. Without dismissing the world of ways in which various aspects of Alexander-myth may have been …

Introduction To Theatre Oer Course, Carmen R. Meyers

Open Educational Resources

Study of theatre and performance throughout history and across cultures including an examination of European, Carribean, and North and South American theatrical styles and genres.

This course is organized for a hybrid/asynchronous format. Our class meets on-campus every week for 75 minutes and the other 75 minutes will be completed asynchronously with weekly learning modules on Blackboard.

The first half of the course focuses on the history of theatre from Ancient Greece through Modern Realism. The second half of the course, students engage in the procedures of professional theatre artists through writing and refining a dramatic text; enacting a performance; …

Kenyon Collegian - January 18, 2024

The Kenyon Collegian

No abstract provided.

Making The Connection: How Membrane Contact Sites Have Changed Our View Of Organelle Biology, G. Voeltz, E. Sawyer, G. Hajnóczky, W. Prinz

Department of Pathology, Anatomy, and Cell Biology Faculty Papers

The view of organelles and how they operate together has changed dramatically over the last two decades. The textbook view of organelles was that they operated largely independently and were connected by vesicular trafficking and the diffusion of signals through the cytoplasm. We now know that all organelles make functional close contacts with one another, often called membrane contact sites. The study of these sites has moved to center stage in cell biology as it has become clear that they play critical roles in healthy and developing cells and during cell stress and disease states. Contact sites have important roles …

Montana Kaimin, January 18, 2024, Students Of The University Of Montana, Missoula

Montana Kaimin, 1898-present

Student newspaper of the University of Montana, Missoula.

Acetylcholine Receptor Based Chemogenetics Engineered For Neuronal Inhibition And Seizure Control Assessed In Mice, Katelyn N Benthall, Jillian Iafrati, Jesslyn Homidan, Jacob T Bendor, Barna Dudok, Jordan S Farrell, Tilo Gschwind, Charlotte L Porter, Annahita Keravala, G Steven Dodson, Ivan Soltesz

Faculty, Staff and Students Publications

Epilepsy is a prevalent disorder involving neuronal network hyperexcitability, yet existing therapeutic strategies often fail to provide optimal patient outcomes. Chemogenetic approaches, where exogenous receptors are expressed in defined brain areas and specifically activated by selective agonists, are appealing methods to constrain overactive neuronal activity. We developed BARNI (Bradanicline- and Acetylcholine-activated Receptor for Neuronal Inhibition), an engineered channel comprised of the α7 nicotinic acetylcholine receptor ligand-binding domain coupled to an α1 glycine receptor anion pore domain. Here we demonstrate that BARNI activation by the clinical stage α7 nicotinic acetylcholine receptor-selective agonist bradanicline effectively suppressed targeted neuronal activity, and controlled both …

Obesity And Skeletal Fragility

Faculty, Staff and Students Publications

Skeletal fracture has recently emerged as a complication of obesity. Given the normal or better than normal bone mineral density (BMD), the skeletal fragility of these patients appears to be a problem of bone quality rather than quantity. Type 2 diabetes mellitus (T2DM), the incidence of which increases with increasing body mass index, is also associated with an increased risk for fractures despite a normal or high BMD. With the additional bone pathology from diabetes itself, patients with both obesity and T2DM could have a worse skeletal profile. Clinically, however, there are no available methods for identifying those who are …

Long-Term Open-Label Vebicorvir For Chronic Hbv Infection: Safety And Off-Treatment Responses, Man-Fung Yuen, Scott Fung, Xiaoli Ma, Tuan Nguyen, Tarek Hassanein, Hie-Won Hann, Magdy Elkhashab, Ronald Nahass, James Park, Ira Jacobson, Walid Ayoub, Steven-Huy Han, Edward Gane, Katie Zomorodi, Ran Yan, Julie Ma, Steven Knox, Luisa Stamm, Maurizio Bonacini, Frank Weilert, Alnoor Ramji, Michael Bennett, Natarajan Ravendhran, Sing Chan, Douglas Dieterich, Paul Yien Kwo, Eugene Schiff, Ho Bae, Jacob Lalezari, Kosh Agarwal, Mark Sulkowski

Department of Medicine Faculty Papers

BACKGROUND & AIMS: The investigational first-generation core inhibitor vebicorvir (VBR) demonstrated safety and antiviral activity over 24 weeks in two phase IIa studies in patients with chronic HBV infection. In this long-term extension study, patients received open-label VBR with nucleos(t)ide reverse transcriptase inhibitors (NrtIs).

METHODS: Patients in this study (NCT03780543) previously received VBR + NrtI or placebo + NrtI in parent studies 201 (NCT03576066) or 202 (NCT03577171). After receiving VBR + NrtI for ≥52 weeks, stopping criteria (based on the treatment history and hepatitis B e antigen status in the parent studies) were applied, and patients either discontinued both VBR …

Effect Of Testosterone Replacement Therapy On Sexual Function And Hypogonadal Symptoms In Men With Hypogonadism, A Michael Lincoff, Steven E Nissen, Mohit Khera, Michael G Miller, Panagiotis Flevaris, Xue Li, Kathleen Wannemuehler, Shalender Bhasin

Faculty, Staff and Students Publications

Context: Few long-term randomized trials have evaluated the efficacy of testosterone replacement therapy (TRT) in improving sexual function and hypogonadal symptoms in men with hypogonadism and whether effects are sustained beyond 12 months.

Objective: The Testosterone Replacement therapy for Assessment of long-term Vascular Events and efficacy ResponSE in hypogonadal men (TRAVERSE) study evaluated the effect of TRT on major adverse cardiovascular events in middle-aged and older men with hypogonadism. The Sexual Function Study, nested within the parent trial, determined testosterone's efficacy in improving sexual activity, hypogonadal symptoms, libido, and erectile function among men reporting low libido.

Methods: Among 5204 men, …

Pilot Implementation Of A Nutrition-Focused Community-Health-Worker Intervention Among Formerly Chronically Homeless Adults In Permanent Supportive Housing, Farrah Hmaidan, Clara Smith, Eva Thibaudeau-Graczyk, Shreela V Sharma

Faculty, Staff and Student Publications

Food insecurity is a known health equity threat for formerly chronically homeless populations even after they transition into permanent housing. This project utilized a human-centered design methodology to plan and implement a nutrition-focused community-health-worker (CHW) intervention in permanent supportive housing (PSH). The project aimed to increase access to healthy foods, improve nutritional literacy, healthy cooking/eating practices, and build community/social connectedness among 140 PSH residents. Validated food-security screening conducted by CHWs identified low or very low food security among 64% of 83 residents who completed the baseline survey, which is similar to rates found in a previous study among formerly homeless …

Revealing Chronic Disease Progression Patterns Using Gaussian Process For Stage Inference, Hongyu Wang, Xiaobo Zhou

Faculty, Staff and Student Publications

OBJECTIVE: The early stages of chronic disease typically progress slowly, so symptoms are usually only noticed until the disease is advanced. Slow progression and heterogeneous manifestations make it challenging to model the transition from normal to disease status. As patient conditions are only observed at discrete timestamps with varying intervals, an incomplete understanding of disease progression and heterogeneity affects clinical practice and drug development.

MATERIALS AND METHODS: We developed the Gaussian Process for Stage Inference (GPSI) approach to uncover chronic disease progression patterns and assess the dynamic contribution of clinical features. We tested the ability of the GPSI to reliably …

Assessment Framework For Bim-Digital Twin Readiness In The Construction Industry, Aljawharah A. Alnaser, Ali Hassan Ali, Haytham H. Elmousalami, Ahmed Elyamany, Ahmed Gouda Mohamed

Civil Engineering

No abstract provided.

A Position Statement On The Post Gene-Therapy Rehabilitation Of Aromatic I-Amino Acid Decarboxylase Deficiency Patients., Hui-Min Lee, Saadet Mercimek-Andrews, Gabriella Horvath, Diana L. Marchese, Richard E. Poulin, Alexis Krolick, Kati-Lyn Tierney, Jasmine Turna, Judy Wei, Wuh-Liang Hwu

Manuscripts, Articles, Book Chapters and Other Papers

Aromatic L-amino acid decarboxylase (AADC) deficiency is a rare genetic disorder of monoamine neurotransmitter synthesis that presents with a range of symptoms, including motor dysfunction and limited attainment of developmental motor milestones. The approval of eladocagene exuparvovec, a gene therapy for AADC deficiency with demonstrated efficacy for motor improvements, now expands the range of motor outcomes possible for patients with this disorder. However, recommendations and guidelines for therapy following treatment with gene therapy are lacking. To ensure patients can reach their full potential following treatment with gene therapy, it is essential they receive rehabilitation therapies designed specifically with their impairments …

Determining Critical Nodes In Optimal Cost Attacks On Networked Infrastructures, Ishfaq Ahmad, Addison Clark, Muhammad Ali, Hansheng Lei, David Ferris, Alex Aved

Informatics and Engineering Systems Faculty Publications

A wide range of critical infrastructures are connected via wide area networks as well as the Internet-of-Thing (IoT). Apart from natural disasters, these infrastructures, providing services such as electricity, water, gas, and Internet, are vulnerable to terrorist attacks. Clearly, damages to these infrastructures can have dire consequences on economics, health services, security and safety, and various business sectors. An infrastructure network can be represented as a directed graph in which nodes and edges denote operation entities and dependencies between entities, respectively. A knowledgeable attacker who plans to harm the system would aim to use the minimum amount of effort, cost, …

Understanding The New Stress Factors Affecting Teachers' Burnout: A Scoping Review, Joby Thomas, Marc Eric S. Reyes

Makara Human Behavior Studies in Asia

The teaching profession is extremely vulnerable to burnout. The sudden outbreak of the COVID-19 pandemic posed new threats and changed the educational environment, the perceptions and the values of teachers. The traditional in-person learning approach was quickly replaced by distant online learning to continue education. As schools reopened, a new educational platform, the hybrid learning model, evolved by fusing the two learning models. The high expectations placed on teachers to swiftly adopt new teaching methods—often without the required resources or training—exacerbated their exhaustion. We conducted a scoping review to determine the new stress factors that cause teachers’ burnout, following the …

Uab Sports And Exercise Medicine Announces New Partnership With Lawson State Athletics, Anna Jones

Browse All News

No abstract provided.

2024-01-19 Message From The Vice President Of Student Affairs, Morehead State University. Office Of Student Affairs.

Staff Congress Records

A message from the Vice President of Student Affairs to the campus community on a drug free work apace from January 18, 2024.

Carbon Cycle–Climate Feedbacks In The Post-Paris World, David S. Schimel, Dustin Carroll

Faculty Research, Scholarly, and Creative Activity

The Paris Agreement calls for emissions reductions to limit climate change, but how will the carbon cycle change if it is successful? The land and oceans currently absorb roughly half of anthropogenic emissions, but this fraction will decline in the future. The amount of carbon that can be released before climate is mitigated depends on the amount of carbon the ocean and terrestrial ecosystems can absorb. Policy is based on model projections, but observations and theory suggest that climate effects emerging in today’s climate will increase and carbon cycle tipping points may be crossed. Warming temperatures, drought, and a slowing …

Self-Consistent Phonon Calculations And Quartic Anharmonic Lattice Thermal Conductivity In 2d Ins Monolayer, Eesha Andharia, Hind Alqurashi, Abhiyan Pandit, Bothina Hamad

Physics Faculty Publications and Presentations

Low lattice thermal conductivity (κ_l) is a crucial factor for higher figure-of merit and hence the efficiency of thermoelectric generators. There are several reports on intrinsically low κ_l values in two-dimensional (2D) van der Waals materials using density functional theory and molecular dynamics simulations. In general, phonon dispersions are studied at absolute zero temperature using the finite-displacement approach within harmonic approximations. In addition, the κ_l is calculated using the third-order cubic interatomic force constants (IFCs) by solving the Boltzmann transport equation for phonons. In these calculations, we use quartic IFCs to solve self-consistent phonon equations …

Measuring Policy, Systems, And Environmental Changes At Elementary Schools Involved In Snap-Ed New Mexico Programming, 2018-2022, Camille Velarde, Erica Landrau-Cribbs, Mahtab Soleimani, Theresa H Cruz

Pediatrics Research and Scholarship

INTRODUCTION: In 2018, the New Mexico Supplemental Nutrition Assistance Program-Education (SNAP-Ed NM) incorporated policy, systems, and environmental (PSE) strategies into the state plan to increase healthy eating and physical activity. Studies of multiple PSE strategies in elementary schools are lacking.

METHODS: We conducted assessments of physical activity and nutrition environments at 11 elementary schools in New Mexico before and after schools were given school-specific PSE recommendations and technical assistance. Baseline data were collected in 2018 by using the School Physical Activity and Nutrition Environment Tool (SPAN-ET), which measures policy, situational, and physical environments in elementary schools. PSE scores were calculated …