Digital Commons Network^™

Challenges Of Local Public Administration In Conflict -Affected Countries: Case Of Hadhramaut Governorate In Yemen, Istanbool Ba Abbad

Theses and Dissertations

This thesis explores the challenges local public administration faced in Hadhramaut, Yemen, and explores avenues for reform. The study's main question is: "What are the main challenges confronting local public administration in Hadhramaut, and what pathways can be pursued for reform?" Hadhramaut, known for its relative stability within Yemen's political unrest, was selected as the case study. Despite its stability, the governorate struggles with challenges arising from the conflict. The research aimed to uncover these challenges and suggest guidelines for recovery, envisioning the governorate as a model for the country. The research aimed to investigate the challenges confronted by public …

Exploring A Gene Panel For Parkinson’S Disease In An Egyptian Cohort, Asmaa Saeed Gabr

Theses and Dissertations

Parkinson’s disease is a highly heterogeneous disorder characterized by diverse neuropathological features, clinical presentations and progression patterns. In Egypt, Parkinson’s disease incidence rates lie outside the range reported elsewhere. The genetic background to the pathogenesis of Parkinson's disease has been postulated for a long time. However, Parkinson’s disease has never been systematically investigated in Egypt. This study aimed to explore genetic variants and interactions that are associated with the familial and sporadic forms of Parkinson's disease in an Egyptian cohort. This includes examining variants in PD-related genes, exploring the role of specific genes like MAPT and adjacent genomic regions, and …

The Impact Of Sharing Economy Platforms On Tourism: Opportunities, Challenges, And Future Directions, Mehmet Bahar

Journal of Global Hospitality and Tourism

The sharing economy is a socio-economic phenomenon where surplus goods and services, aided by technology, are shared mutually among those in need and providers, coming together to exchange these goods and services. Economic crises, environmental issues, changes in social life, and technological advancements have led to the emergence of the sharing economy as an alternative model to existing goods and services. In this regard, the tourism sector has also been affected by this change, offering new travel and holiday alternatives, competitive advantages to stakeholders, the creation of new income sources, and the establishment of a more sustainable approach. Consequently, this …

Investigating The Malting Suitability And Brewing Quality Of Different Rice Cultivars, Bernardo P. Guimaraes, Florian Schrickel, Nils Rettberg, Shannon R. M. Pinson, Anna M. Mcclung, Kaushik Luthra, Griffiths G. Atungulu, Xueyan Sha, Christian De Guzman, Scott Lafontaine

Food Science Faculty Publications and Presentations

Nineteen globally diverse rice cultivars were analyzed for various chemical parameters important to malting, including germination energy, protein, apparent amylose content, and gelatinization temperatures (GT). The rice cultivars were then malted, and congress mashes were produced. Several parameters important to brewing were then assessed in the malts and worts (i.e., extract, soluble protein, free amino nitrogen (FAN), GT, etc.). The rice malts produced were saccharified to varying degrees, had high limit dextrinase activities, and contained sufficient FAN/protein concentrations. This suggests their potential to yield robust fermentations in beer styles with high adjunct inclusions without requiring additional nitrogen supplementation. Rice cultivars …

The Relationship Between Cognitive Impairment In Psychiatric Patients And Readmission Rate To An Inpatient Facility, Cherilyn Isis Schuff

Theses and Dissertations

The primary intention of this study was to further understand the impact of assessing cognitive impairment in psychiatric patients, as a mediating factor on readmission rates. Mild cognitive dysfunction impacts a patient’s functional outcomes (Bowie & Harvey, 2006; Davis et al., 2012; Marcantonio, et al., 2001). Little information exists to guide best practices in the treatment of adults with cognitive impairment who are hospitalized for acute conditions (Davis et al., 2012). A cognitive impairment may impact patient prognosis and ability to function outside of a setting focused on stabilization. Neuropsychological testing is a valuable tool in predicting a patient’s cognitive …

World Transit Research February 2024 Newsletter, Institute Of Transport Studies Monash University

World Transit Research Newsletter

No abstract provided.

Agricultural Groundcover Update January 2024, Justin Laycock

Natural resources published reports

Summary

• About 94% of the grainbelt had adequate (more than 50%) vegetative groundcover to prevent wind erosion in January 2024.
• In the northern half of the grainbelt, a larger-than-average area has 51–60% groundcover, which is expected to decrease to below 50% over the coming months.
• Just under 6% of the grainbelt (855,000 ha) had less than 50% groundcover, which is inadequate to prevent wind erosion. West Midlands Ag Soil Zone had the highest risk of wind erosion and 14.5% of this farmland had inadequate groundcover.
• Less than 0.5% of the grainbelt had a high to very high risk of wind …

The Trucking Industry, Working From Home, Covid-19, And Positive Social Change Effects, Martin Lulgjuraj

Walden Dissertations and Doctoral Studies

No abstract provided.

Spatial Accessibility And Travel To Pharmacy By Type In The Detroit Region, Xiaomeng Li, Igor Vojnovic, Arika Ligmann-Zielinska

School of Natural Resources: Faculty Publications

Background

Community pharmacies are a critical part of the health care provision system. Yet less is understood about the spatial accessibility to pharmacies and how people travel to reach these services.

Objectives

This study compared spatial accessibility and actual travel to different types of pharmacies among selected neighborhoods in the Detroit region.

Methods

Three types of neighborhoods were selected and compared, including two lower income Black urban neighborhoods of high-density and four upper income White suburbs (two of low density and two of high density). Spatial accessibility was computed by pharmacy type and compared among neighborhoods using ANOVA. Pharmacy trips …

A Conversation On The Carceral Home, Ngozi Okidegbe, Kate Weisburd, Emmett Sanders, James Kilgore

Faculty Scholarship

On February 8, 2024, scholars Ngozi Okidegbe, Kate Weisburd, Emmett Sanders, and James Kilgore met virtually at the Boston University School of Law to hold a conversation on Professor Weisburd’s article, The Carceral Home, 103 B.U. L. Rev. 1879 (2023).

Optimum Phosphate Ion Removal From Aqueous Solutions Using Roller Kiln Industrial Solid Waste, Dalia Amer Ali, Walaa A. Abdelwahab, Mai Hassan Roushdy

Chemical Engineering

Water scarcity is the most imperative predicament that concerns the population. In this research, a roller kiln (RK) industrial solid waste was used in the adsorption of phosphate ions from aqueous solutions thus converting a waste to wealth through aiding in serving as a water treatment application. The RK waste was produced from an Egyptian factory with a fow rate of million tons/ day. Surface characterization for this solid waste was performed including transmission electron microscopy (TEM), X-ray difraction (XRD), X-ray fuorescence (XRF), Fourier transform infra-red (FTIR), zeta potential (ZP), and particle size distribution (PSD). Based on the kinetics and …

The Biology Of Hope: Inflammatory And Neuroendocrine Profiles In Ovarian Cancer Patients, Susan K Lutgendorf, Rachel M Telles, Brendan Whitney, Premal H Thaker, George M Slavich, Frank J Penedo, Steven W Cole, Anil K Sood, Benjamin W Corn

Faculty, Staff and Student Publications

INTRODUCTION: Although the concept of hope is highly relevant for cancer patients, little is known about its association with cancer-relevant biomarkers. Here we examined how hope was related to diurnal cortisol and interleukin-6 (IL-6), a pro-inflammatory cytokine previously associated with tumor biology and survival in ovarian cancer. Secondly, we examined whether hope and hopelessness are distinctly associated with these biomarkers.

METHOD: Participants were 292 high-grade ovarian cancer patients who completed surveys and provided saliva samples 4x/daily for 3 days pre-surgery to assess diurnal cortisol. Blood (pre-surgery) and ascites were assessed for IL-6. Hope and hopelessness were assessed using standardized survey …

Deep Learning-Based Automatic Segmentation Of Cardiac Substructures For Lung Cancers, Xinru Chen, Raymond P Mumme, Kelsey L Corrigan, Yuki Mukai-Sasaki, Efstratios Koutroumpakis, Callistus M Nguyen, Kai Huang, Cenji Yu, Ting Xu, Aji Daniel, Peter A Balter, Xiaodong Zhang, Joshua S Niedzielski, Sanjay S Shete, Anita Deswal, Laurence E Court, Zhongxing Liao, Jinzhong Yang

Faculty, Staff and Student Publications

Purpose: Accurate and comprehensive segmentation of cardiac substructures is crucial for minimizing the risk of radiation-induced heart disease in lung cancer radiotherapy. We sought to develop and validate deep learning-based auto-segmentation models for cardiac substructures.

Materials and methods: Nineteen cardiac substructures (whole heart, 4 heart chambers, 6 great vessels, 4 valves, and 4 coronary arteries) in 100 patients treated for non-small cell lung cancer were manually delineated by two radiation oncologists. The valves and coronary arteries were delineated as planning risk volumes. An nnU-Net auto-segmentation model was trained, validated, and tested on this dataset with a split ratio of 75:5:20. …

Mediators Of Necroptosis: From Cell Death To Metabolic Regulation, Xiaoqin Wu, Laura E Nagy, Jérémie Gautheron

Faculty, Staff and Student Publications

Necroptosis, a programmed cell death mechanism distinct from apoptosis, has garnered attention for its role in various pathological conditions. While initially recognized for its involvement in cell death, recent research has revealed that key necroptotic mediators, including receptor-interacting protein kinases (RIPKs) and mixed lineage kinase domain-like protein (MLKL), possess additional functions that go beyond inducing cell demise. These functions encompass influencing critical aspects of metabolic regulation, such as energy metabolism, glucose homeostasis, and lipid metabolism. Dysregulated necroptosis has been implicated in metabolic diseases, including obesity, diabetes, metabolic dysfunction-associated steatotic liver disease (MASLD) and alcohol-associated liver disease (ALD), contributing to chronic …

Txnrd1 Drives The Innate Immune Response In Senescent Cells With Implications For Age-Associated Inflammation, Xue Hao, Bo Zhao, Martina Towers, Liping Liao, Edgar Luzete Monteiro, Christina Freeman, Hsin-Yao Tang, Aaron Havas, Andrew V Kossenkov, Shelley L Berger, Peter D Adams, David W Speicher, David Schultz, Ronen Marmorstein, Kenneth S Zaret, Rugang Zhang

Faculty, Staff and Student Publications

Sterile inflammation, also known as 'inflammaging', is a hallmark of tissue aging. Cellular senescence contributes to tissue aging, in part, through the secretion of proinflammatory factors collectively known as the senescence-associated secretory phenotype (SASP). The genetic variability of thioredoxin reductase 1 (TXNRD1) is associated with aging and age-associated phenotypes such as late-life survival, activity of daily living and physical performance in old age. TXNRD1's role in regulating tissue aging has been attributed to its enzymatic role in cellular redox regulation. Here, we show that TXNRD1 drives the SASP and inflammaging through the cyclic GMP-AMP synthase (cGAS)-stimulator of interferon genes (STING) …

Minimal Information For Studies Of Extracellular Vesicles (Misev2023): From Basic To Advanced Approaches, Joshua A Welsh, Deborah C I Goberdhan, Lorraine O'Driscoll, Edit I Buzas, Cherie Blenkiron, Houjian Cai, Tom A P Driedonks, Uta Erdbrügger, Juan M Falcon-Perez, Qing-Ling Fu, Andrew F Hill, Metka Lenassi, Sai Kiang Lim, Mỹ G Mahoney, Sujata Mohanty, Andreas Möller, Rienk Nieuwland, Takahiro Ochiya, Susmita Sahoo, Ana C Torrecilhas, Lei Zheng, Andries Zijlstra, Sarah Abuelreich, Reem Bagabas, Paolo Bergese, Esther M Bridges, Marco Brucale, Dylan Burger, Randy P Carney, Emanuele Cocucci, Rossella Crescitelli, Edveena Hanser, Adrian L Harris, Norman J Haughey, An Hendrix, Alexander R Ivanov, Tijana Jovanovic-Talisman, Nicole A Kruh-Garcia, Vroniqa Ku'ulei-Lyn Faustino, Diego Kyburz, Cecilia Lässer, Kathleen M Lennon, Jan Lötvall, Adam L Maddox, Elena S Martens-Uzunova, Rachel R Mizenko, Lauren A Newman, Andrea Ridolfi, Eva Rohde, Tatu Rojalin, Andrew Rowland, Andras Saftics, Ursula S Sandau, Julie A Saugstad, Faezeh Shekari, Simon Swift, Dmitry Ter-Ovanesyan, Juan P Tosar, Zivile Useckaite, Francesco Valle, Zoltan Varga, Edwin Van Der Pol, Martijn J C Van Herwijnen, Marca H M Wauben, Ann M Wehman, Sarah Williams, Andrea Zendrini, Alan J Zimmerman, Clotilde Théry, Kenneth W Witwer

Faculty, Staff and Student Publications

Extracellular vesicles (EVs), through their complex cargo, can reflect the state of their cell of origin and change the functions and phenotypes of other cells. These features indicate strong biomarker and therapeutic potential and have generated broad interest, as evidenced by the steady year-on-year increase in the numbers of scientific publications about EVs. Important advances have been made in EV metrology and in understanding and applying EV biology. However, hurdles remain to realising the potential of EVs in domains ranging from basic biology to clinical applications due to challenges in EV nomenclature, separation from non-vesicular extracellular particles, characterisation and functional …

Neurologic Morbidity And Functional Independence In Adult Survivors Of Childhood Cancer, Stefanie C Vuotto, Mingjuan Wang, M Fatih Okcu, Daniel C Bowers, Nicole J Ullrich, Chenghong Li, Rebecca M Howell, Todd M Gibson, Wendy M Leisenring, Kevin C Oeffinger, Leslie L Robison, Gregory T Armstrong, Kevin R Krull, Tara M Brinkman

Faculty, Staff and Student Publications

OBJECTIVE: To examine associations between neurologic late effects and attainment of independence in adult survivors of childhood cancer treated with central nervous system (CNS)-directed therapies.

METHODS: A total of 7881 survivors treated with cranial radiation therapy (n = 4051; CRT) and/or intrathecal methotrexate (n = 4193; IT MTX) ([CNS-treated]; median age [range] = 25.5 years [18-48]; time since diagnosis = 17.7 years [6.8-30.2]) and 8039 without CNS-directed therapy reported neurologic conditions including stroke, seizure, neurosensory deficits, focal neurologic dysfunction, and migraines/severe headaches. Functional independence was assessed using latent class analysis with multiple indicators (independent living, assistance with routine and personal …

Circulating Tumor Dna And Radiological Tumor Volume Identify Patients At Risk For Relapse With Resected, Early-Stage Non-Small-Cell Lung Cancer, H T Tran, S Heeke, S Sujit, N Vokes, J Zhang, V K Lam, S G Swisher, M C B Godoy, T Cascone, B Sepesi, D L Gibbons, J Wu, J V Heymach

Faculty, Staff and Student Publications

Background: Predicting relapse and overall survival (OS) in early-stage non-small-cell lung cancer (NSCLC) patients remains challenging. Therefore, we hypothesized that detection of circulating tumor DNA (ctDNA) can identify patients with increased risk of relapse and that integrating radiological tumor volume measurement along with ctDNA detectability improves prediction of outcome.

Patients and methods: We analyzed 366 serial plasma samples from 85 patients who underwent surgical resections and assessed ctDNA using a next-generation sequencing liquid biopsy assay, and measured tumor volume using a computed tomography-based three-dimensional annotation.

Results: Our results showed that patients with detectable ctDNA at baseline or after treatment and …

Experiences Of Patients With Peritoneal Carcinomatosis-Related Complex Care Needs And Their Caregivers, Rachel A Pozzar, Jaclyn A Wall, Anna Tavormina, Embree Thompson, Andrea C Enzinger, Susana Campos, Alexi A Wright

Faculty, Staff and Student Publications

Background: Patients with peritoneal carcinomatosis (PC) frequently undergo palliative procedures, yet these patients and their caregivers report being unprepared to manage ostomies, drains, and other complex care needs at home. The purpose of this study was to characterize the unique needs of these patients and their caregivers during care transitions.

Methods: Patients completed measures of health status and advance care planning, caregivers completed measures of preparedness and burden, and all participants completed measures of depression and anxiety. Participants detailed their experiences in individual, semi-structured interviews. We analyzed data using descriptive statistics and conventional content analysis.

Results: Sixty-one patients and 39 …

Intraoperative Language Mapping Guided By Real-Time Visualization Of Gamma Band Modulation Electrocorticograms: Case Report And Proof Of Concept, Kyle R Noll, Priscella Asman, Israt Tasnim, Matthew Hall, Katherine Connelly, Chibawanye Ene, Roxana M Grasu, Ho-Ling Liu, Vinodh A Kumar, Matthew Muir, Sarah Prinsloo, Hayley Michener, Jeffrey S Wefel, Nuri F Ince, Sujit S Prabhu

Faculty, Staff and Student Publications

BACKGROUND: Electrocorticography (ECoG) language mapping is often performed extraoperatively, frequently involves offline processing, and relationships with direct cortical stimulation (DCS) remain variable. We sought to determine the feasibility and preliminary utility of an intraoperative language mapping approach guided by real-time visualization of electrocorticograms.

METHODS: A patient with astrocytoma underwent awake craniotomy with intraoperative language mapping, utilizing a dual iPad stimulus presentation system coupled to a real-time neural signal processing platform capable of both ECoG recording and delivery of DCS. Gamma band modulations in response to 4 language tasks at each electrode were visualized in real-time. Next, DCS was conducted for …

New Algorithmic Support For The Fundamental Theorem Of Algebra, Vitaly Zaderman

Dissertations, Theses, and Capstone Projects

Univariate polynomial root-finding is a venerated subjects of Mathematics and Computational Mathematics studied for four millenia. In 1924 Herman Weyl published a seminal root-finder and called it an algorithmic proof of the Fundamental Theorem of Algebra. Steve Smale in 1981 and Arnold Schonhage in 1982 proposed to classify such algorithmic proofs in terms of their computational complexity. This prompted extensive research in 1980s and 1990s, culminated in a divide-and-conquer polynomial root-finder by Victor Pan at ACM STOC 1995, which used a near optimal number of bit-operations. The algorithm approximates all roots of a polynomial p almost as fast as one …

The Early Late Miocene Cessation Of Deep And Intermediate Water Circulation Through The Central American Seaway, Benjamin Stanley Kwiatkowski

Dissertations, Theses, and Capstone Projects

The state of the middle late Miocene global ocean circulations which regulated climate and affected deep ocean chemical environments were impacted by geographic changes. During the Miocene, cirum-equatorial circulations slowly decreased, which included through the seaway between the Americas called the Central American Seaway (CAS). Its shoaling and ultimate closing led to the onset of modern day oceanic circulation as characterized by the global thermohaline circulation. However, this seaway has a long hotly debated history concerning the timing of its restriction and shallowing owing in part to the shifting of tectonic plates.

The goal of this research focuses on investigating …

Fashion, Freedom, And Feminism: The Transcendent Work Of Rosa Genoni And Her "Tanagra Dress" Reimagined, Christina Trupiano

Dissertations, Theses, and Capstone Projects

The fashion industry itself is broad in scope and dependent upon numerous sub-industries to produce its garments. It is heavily dependent upon machinery of all kinds, yet unlike many industries today, it is still also largely reliant on manual labor, specifically minority women labor. This dependance upon manual labor correlates with its long history of worker exploitation and sweated labor. The concentration of exploitative labor practices in the fashion industry have made it a focal point in the ongoing struggle between workers and the downward pressure capitalism and industrialization placed on worker compensation, quality of life and job security.

This …

Teaching In The “Home Language” Is Not Enough: Navigating Spanish Raciolinguistic Ideologies In A Dual Language Bilingual Program, Gladys Yacely Aponte

Dissertations, Theses, and Capstone Projects

This ethnographic case study examines how fourth graders in a New York City Spanish/English dual language bilingual public school navigate hegemonic language ideologies about Spanish. Drawing on the scholarship of raciolinguistic ideologies—those that position the language practices of people of color as inherently deficient (Flores & Rosa, 2015), I analyze the discourse of seven Kiskeyanx students to examine how they navigate the widespread raciolinguistic marginalization of Kiskeyanxs— a demographic that is racialized as more Black than other Spanish-speaking groups.

As a first-generation Kiskeyana-New Yorker, a bilingual teacher educator and researcher, and a former dual language bilingual public-school teacher, it …

Socially Safe On Smartphones: How Smartphone Use Reduces Social Risk Taking, Diogo Koch Alves

Dissertations, Theses, and Capstone Projects

Consumers are often faced with decisions that carry a degree of social risk, with uncertain outcomes that could impact their social standing. Examples include choosing the ideal outfit to wear to an upcoming party or selecting a gift to give to a friend. Given the prevalence of smartphones in consumer decision making, I investigate the effect of smartphone use on social risk taking. Across seven studies, I find that smartphone use, relative to the use of other devices, results in a lower propensity to make socially risky decisions. I propose that smartphone use, by increasing the salience of one’s social …

A Municipal Modernity: Women, Architecture, And Public Health In Working-Class New York, 1913–1950, Jessica Fletcher

Dissertations, Theses, and Capstone Projects

“A Municipal Modernity” is the first study to analyze the architectural history of the district health centers in New York City that women reformers and their allies founded to address poor health in working-class communities. It reveals that women’s philanthropic adaptive re-use was foundational to the architecture of the public health care in New York and led to a program of municipal district health centers. Philanthropic reformers adapted buildings in the 1910s and 1920s to provide affordable health care for low-income women and children in European immigrant and Black neighborhoods. During the New Deal, municipal officials followed the example set …

Using Leaf Spectra To Elucidate The Taxonomy And Ecology Of Living And Dried Plants, Natalia L. Quinteros Casaverde

Dissertations, Theses, and Capstone Projects

Identifying plants and understanding of changes in plant communities are crucial to the conservation and management of nature. The shortwave spectral reflectance of leaves is a promising tool for rapidly identifying species at different taxonomic ranks and predicting important plant functional traits. However, the spectral reflectance of leaves changes in response to biotic and abiotic conditions.

The aim of this dissertation is to investigate the potential of shortwave spectral reflectance to investigate (Chapter 1) how its variation affects the accuracy of methods used to predict plant taxonomies and what environmental factors most influence biophysically predicted traits, (Chapter 2) what are …

Power And The Press: Reimagining The World By Producing Information Together, Jen Hoyer

Dissertations, Theses, and Capstone Projects

This study of three collectively-organized activist printing projects examines how information production is a strategy for communities to reimagine and reconfigure oppressive power structures. I consider the High School Student Union and their newspaper, the High School Free Press; the women’s collective that took over RAT Subterranean News; and WIMP, a radical printing collective that broke away from the New York City Students for a Democratic Society chapter and supported a variety of progressive movements in New York City in the late 1960s and early 1970s. This research examines how dissatisfaction with oppressive power structures leads individuals to build collective …

Cinema And Ritual: Decolonial Feminist Approaches To Image-Making In The Americas And The Caribbean, Natalie M. Erazo

Dissertations, Theses, and Capstone Projects

This thesis project is composed of an open-access syllabus hosted on a CUNY commons site, as well as a paper that examines various films and texts responding to the theme of cinema and ritual. Referenced films will focus on ritual as a decolonial feminist methodological framework, rooted primarily in Afro-descended and Indigenous cosmovisions within Latin America and the Caribbean. From a dance ritual spell warding off U.S. imperialism in present-day Puerto Rico, to a poetic visual eulogy for murdered women in rural Mexico, to a community prayer to Yemaya bringing relief for water scarcity in Cuba to a cautionary tale …

Stereospecific Cross-Coupling Reactions Of Enantioenriched Secondary Alkyltricyclohexyltin Nucleophiles, Meruyert Binayeva

Dissertations, Theses, and Capstone Projects

Transition metal-catalyzed cross-coupling reactions have evolved into a remarkable instrument for the formation of new bonds, and have significantly impacted how we approach to access complex organic molecules. Palladium is currently one of the most popular elements for catalytic applications due to its ability to facilitate powerful carbon-carbon and carbon-heteroatom couplings. Traditional Pd-catalyzed cross-coupling reactions have primarily concentrated on C(sp2)-C(sp2) cross-couplings, yielding planar products. Considering the use of C(sp3) nucleophiles would offer a viable control of the three dimensional arrangement in molecules. Herein, the first chapter details the history and development of Pd-catalyzed Stille cross-coupling reactions. The use of configurationally …