Bap1 Loss Links Myc Activation, Stress Response Vulnerability, And Disease Progression In Kidney Cancer, Ilya Strunilin

Arts & Sciences Graduate Student Theses and Dissertations

BAP1, a chromatin modifier, is a frequently mutated tumor suppressor in clear cell renal cell carcinoma (ccRCC). Mutations in BAP1 are associated with a more aggressive and lethal disease. However, the downstream mediators of BAP1 loss in ccRCC oncogenesis are not well understood. To better understand mechanisms of BAP1-mediated tumor suppression, I have extensively characterized the very early transcriptional mediators of BAP1 loss in a postnatal kidney-specific genetic knockout model. Because VHL loss is the initiating event in ccRCC, we modeled Bap1 loss in a Vhl-deficient background. I have found that Vhl/Bap1 double-knockout cells of PT segment S2 strongly activate …

Women And Wars: Understanding Women’S Political Empowerment Post- Conflict In France, Lebanon, And Sierra Leone, Alaa S. Sayed

Theses and Dissertations

This thesis attempts to discusses how conflict can be a time of change for women and how conflict can be a crucial aspect for change and improvement. Conflict provides a chance for the women to witness and experience the disruption of gender roles, which was a common practice during wartime, as women were placed in roles that were not officially theirs, according to what society adheres to or ascribes as acceptable roles for women. The conflict is presented as a “window” of opportunity. However, the reality of the situation of this “window” is not uniform across all post-conflict societies; the …

Fatherhood In Egypt: Identity Formation And Role Theory Perspectives, Mahmoud Nasr Gawdat

Theses and Dissertations

Fatherhood is a central yet under-researched dimension of family life in Egypt, particularly from a psychological and identity-based perspective. This study explores how Egyptian fathers construct and experience fatherhood through the lenses of identity theory and role theory. Using a qualitative research design, seven focus groups were conducted with 43 Egyptian fathers to examine the meanings they attribute to fatherhood, their perceived roles, challenges, support systems, and personal transformations. Thematic analysis revealed six interconnected themes: (1) describing the father’s role, (2) learning the father role, (3) social and cultural influences on the father role, (4) meaning of being a father, …

Experimental And Numerical Analyses Of Eccentric Bolted Connections Subject To Shear And Torsion, Mohannad Mahran Zanaty

Theses and Dissertations

Steel connections are one of the pillars of the steel structures construction industry, and yet, it still to this day holds some ambiguities in our design procedures. Several authors believe that the elastic-based methods constricted connection design into a conservative approach, and accordingly initiated a method called Instantaneous Center, which is a method indicating that the center of rotation is around a fictitious point. The method was investigated analytically by exploring the domain and found the method often present multiple roots, with one of the roots often indicating an unrealistic point of rotation with a marginally high exaggerated capacity of …

A Novel Design-For-Test Flow Using Librelane, Mohamed E. Gaber

Theses and Dissertations

Design-for-testing is a crucial element of application-specific integrated circuit design, yet, in the nascent open-source electronic design automation scene, the solutions for it are sorely limited. Design-for-test-enabled chips allow defects to be caught early on in the manufacturing process, avoiding incurring huge costs if hardware with defective chips is shipped to equipment manufacturers or, worse, end-users. Yet, the current open-source solutions rely on a brute-force utility that does not scale and negatively impacts the design by holding design-for-testing features as co-equal with the design’s regular operation, and a nominally layout-aware solution that does not holistically integrate into a larger flow. …

Enhancing The Performance Of Brain-Computer Interfaces Via A Spatially-Aware Framework, Ahmed Ayman Eloraby

Theses and Dissertations

Electroencephalography (EEG)-based brain–computer interfaces (BCIs) provide a non-invasive pathway for communication, with the P300 speller being one of the most established paradigms. Despite its practicality, EEG signals present inherent challenges, including low signal-to-noise ratio, high dimensionality, and limited spatial resolution. These characteristics complicate the extraction of discriminative spatial patterns, which are critical for accurate P300 detection and character-level decoding.

This thesis addresses these challenges through the development of AttenPCA-Net, a deep learning framework that integrates spatially-aware processing with dimensionality reduction. Principal Component Analysis (PCA) is employed to reduce redundancy and noise while preserving the most informative components of the EEG …

Educational Governance And Policy Implementation In Conflict-Affected Contexts: The Case Of Hadhramout, Yemen, Naa'ma M. Al-Hendi

Theses and Dissertations

Education remains a vital component of societal resilience and development in a world increasingly defined by conflict and instability. Education during conflict is crucial for academic learning and providing essential life skills and psychosocial support to children affected by war. Yemen is being plagued by political upheaval and a lack of economic flow to keep education running efficiently. Although Hadhramout, a governorate in Yemen, remains relatively stable, its education sector continues to face persistent challenges that hinder the quality and effectiveness of education. This study investigates the key challenges facing K-12 education in Hadhramout and examines the extent to which …

Instagram Influencers And Egyptian Women: Links To Self- Perception And Behavior, Fatma El Sayad

Theses and Dissertations

The rapid rise of Instagram influencers has transformed the ways young women engage with media, shaping perceptions of appearance, lifestyle, success, and everyday behavior. This study examines how frequent exposure to Instagram influencers affects self-esteem, internalization of beauty and lifestyle ideals, perceived realism of influencer content, and behavioral and consumption habits among young Egyptian females. The study explores participants’ lived experiences, interpretations, and coping strategies in relation to influencer culture. Perceived influencer credibility emerged as a key factor for females to follow them, influencers viewed as relatable, specialized, and transparent were more likely to inspire adaptive behaviors, whereas those promoting …

Creating Public Value Through Public-Private Partnerships In Technical And Vocational Education And Training In Egypt, Aseel Amr Tajuddin

Theses and Dissertations

Technical and Vocational Education and Training (TVET) has emerged in the last decade as a foundational pillar for Egypt’s workforce and economic development vision. More recently, the Egyptian Ministry of Education and Technical Education (MoETE) has scaled industry driven and Public Private Partnerships (PPPs) TVET models, industry affiliated dual education programs and Applied Technology Schools (ATS), seeking to strengthen alignment with the labor market and improving TVET graduates employability. Yet, TVET in Egypt continues to suffer from persistent social stigma, limited social legitimacy and low social ranking, despite the state led reform efforts. Existing TVET literature remains limited to examining …

Between Reform And Dependency: Ifi Influence On Egyptian Food Sovereignty, Nayera Ayman Abouelfarh

Theses and Dissertations

This thesis examines how international financial institutions (IFIs), particularly the International Monetary Fund (IMF) and the World Bank, have influenced Egyptian food sovereignty between 2016 and 2024. It asks how IFI-backed structural adjustment programs, policy influence, and ideational influence reshaped Egyptian public policy and affected the state’s capacity to autonomously manage its food system. The thesis argues that IFI-driven reform agendas prioritized macroeconomic stabilization, fiscal discipline, and export-oriented growth over food sovereignty, increasing Egypt’s external dependence and vulnerability to global market shocks. Methodologically, the study employs a qualitative comparative case study design combining process tracing and thematic document analysis using …

Fathers’ Footprints: The Role Of The Father-Son Relationship In Shaping Men’S Experience And Expression Of Anger In Egypt, Lydia E. Wassef

Theses and Dissertations

Abstract

In many Egyptian families, the father holds a central position as an authority figure, a protector, and a provider, yet often remains emotionally reserved and relationally distant. The emotional legacy of paternal acceptance or rejection extends into adulthood, shaping patterns of emotional regulation. Particularly, the father-son relationship plays a fundamental role in shaping men’s experiences and expressions of anger. Within cultural contexts discouraging vulnerability and associating masculinity with strength and emotional restraint, anger may become one of the few socially acceptable modes of emotional expression for men. This study positions these dynamics within the cultural context of fatherhood in …

An Integrated Sensor-Fusion Framework For Performance-Based Compensation In Construction, Aly Ayman El-Ashry

Theses and Dissertations

Construction productivity has historically stagnated due to a reliance on subjective labor monitoring and “lagging” performance indicators. This research proposes a novel compensation model with the use of Total Energy Management System (TEMS) to translate labor effort and efficiency into payment incentives with the integration of Internet of Things (IoT) wearables and Statistical Process Control (SPC) charts.

This research addresses the systemic problem of declining construction productivity caused by industry’s inability to objectively quantify human effort. While traditional models rely on post-facto production tallies, a significant research gap exists in real-time physiological labor monitoring. To bridge this, the proposed TEMS …

Protection Mechanisms’ Analysis Of Gender-Based Violence Among Refugees In Egypt, George Fattah

Theses and Dissertations

Gender-Based Violence remains a critical protection challenge in humanitarian settings, yet the mechanisms that determine who reports violence, and who receives care, are often uneven. In Egypt, current data reveals significant disparities in reporting rates across demographic groups, prompting a deeper inquiry into the inclusivity of existing protection frameworks. This study investigates the structural, economic, and socio-cultural factors that influence both the reporting of GBV and the delivery of services to refugee survivors. By examining the lived experiences of different migrant groups, the research interrogates how legal precarity and identity markers interact to create distinct barriers to justice and support. …

Breaking The Silence: A Content And Expert Analysis Of The 2025 Ramadan Series Lam Shamseya's Framing And Subversion Of Child Sexual Abuse Discourse In Egypt, Maya Abouelnasr

Theses and Dissertations

This thesis analyzes how the 2025 Egyptian TV series Lam Shamseya served as a sociocultural intervention and awareness platform for reframing and subverting the typical child sexual abuse (CSA) discourse in Egypt. Using a mixed-methods approach, the study triangulates framing theory and two complementary tools of the critical discourse analysis (CDA) and the circuit of culture model through a scene-level content analysis of 304 scenes across all 15 episodes of the series and ten semi-structured interviews with media experts, media practitioners, and psychologists. Key findings include reported corroboration of subversion of traditional tropes and archetypes, as well as reframing of …

Beyond Emergency: Charting Pathways To Sustainable Development In Fragile And Conflict-Affected Settings: A Case Study Of Yemen, Sharif Abdurabu Salem Farid Alsahbool

Theses and Dissertations

For nearly a decade, Yemen's eastern governorates of Hadramawt, Shabwah, and Al‑Mahrah have been relatively stable, yet the international aid system has kept delivering short‑term humanitarian relief like food baskets and water trucking instead of shifting to sustainable development that could rebuild people's lives, create jobs, fix infrastructure, and strengthen local government. This thesis investigates why this transition has taken so long. Based on 21 interviews with government officials, international NGO staff, and local NGO managers in these three governorates, the study develops a new way of understanding the problem. It introduces three ideas: the 'emergency mentality', which is a …

The Paradox Of Palestinian Exile: Unrwa, Structural Limbo, And The Manufactured Crisis Of The Right To Return, Laila Ibrahim Hassan Elkassas

Theses and Dissertations

This thesis argues that the temporariness of Palestinian exile has been turned into a manufactured limbo that is sustained by international law, humanitarian governance and host- country regimes. It uses General Assembly Resolution 194 and the broader human rights regime to show how the right to return is constantly reaffirmed but structurally postponed, resulting in a gap between legal promise and political reality. Drawing on Edward Said’s notion of exile as an unhealable rift, Pierre Bourdieu’s concept of habitus and Didier Fassin’s thinking on humanitarian reason, the thesis constructs a multi-scalar framework that conceptualizes limbo as existential experience, embodied practice …

Determinants Of Corporal Punishment And Severe Physical Punishment In Egypt: A Mixed-Methods Analysis For Child Protection Policy, Marwa Moustafa Nassef

Theses and Dissertations

Corporal punishment (CP) and severe physical punishment (SPP) remain a major public health, child rights, and child protection policy concern. In Egypt, despite legislative reforms, survey-weighted analysis of the 2021 Egypt Family Health Survey (EFHS) 2021 (CAPMAS, 2022) reveals prevalence rates of 60.5% for CP and 27.4% for SPP among children aged 1–14 (author’s calculations using EFHS-2021, n=7623), yet evidence distinguishing the determinants of routine corporal punishment from escalation to severe physical punishment remains limited in low- and middle-income contexts. Guided by Bronfenbrenner’s ecological framework, this mixed-methods study identifies key drivers of CP and its escalation to SPP among Egyptian …

Structure Functions For The Inclusive Semileptonic B-Quark Decay At Nnlo: A Semi-Analytic Calculation, A. Broggio, B. Capdevila, A. Ferroglia, P. Gambino

Publications and Research

We present a study of the inclusive charmless semileptonic b decay, b → X_uℓv at next-to-next-to-leading order (NNLO) in perturbative QCD, with the primary aim of extracting the hadronic structure functions Wi at NNLO. The analysis is based on a numerical calculation of the relevant kinematic distributions using a phase-space slicing method to handle infrared-sensitive contributions from real gluon emissions. We use known results from Heavy Quark Effective Theory and Soft-Collinear Effective Theory to extract the singular terms and construct a model for the regular contributions to the structure functions at NNLO, then perform a fit to the …

Re: Comment Letter For The Butte Priority Soils Operable Unit (Bpsou) 2025 Butte Reclamation Evaluation System (Bres) Site Specific Corrective Action Plans For Quadrant 2, Molly Roby

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

Radiometric Modeling And Glamr Comparison For Cpf Hysics Independent Calibration, Zhipeng (Ben) Wang, Kurtis Thome, Brian Wenny

The Characterization and Radiometric Calibration for Remote Sensing Annual Meeting (CALCON)

The Independent Calibration (IndCal) approach for the CLARREO Pathfinder (CPF) mission HySICS instrument targets SI-traceable absolute radiometric calibration at the sub-percent level. As a major element of IndCal, a physics-based endto- end instrument model of HySICS has been developed to predict spectral and radiometric behavior.

As part of HySICS pre-launch characterization, detector-based absolute radiometric calibration was performed using the NASA Goddard’s GLAMR, which is a tunable laser-based calibration system covering the 340–2500 nm spectral range. In this study, model predictions are compared with GLAMR measurements and other pre-launch component- and system-level calibration results. Special emphasis is placed on the effects …

Pace Oci On-Orbit Solar Calibration, Jeff Mcintire, Shihyan Lee, Robert E. Eplee, Gerhard Meister

The Characterization and Radiometric Calibration for Remote Sensing Annual Meeting (CALCON)

The launch of the Plankton, Aerosol, Cloud, ocean Ecosystem (PACE) mission in February of 2024 was a significant step forward for the observation of ocean science data from low Earth orbit. PACE has a payload of two polarimeters and the Ocean Color Instrument (OCI); OCI is the next generation sensor for ocean color science, drawing heritage from sensors such as MODIS, SeaWiFS, and VIIRS, but with increased spectral coverage and improved accuracy. OCI is a grating spectrometer with hyperspectral coverage from the ultraviolet (about 315 nm) to near-infrared (about 895 nm), with additional filtered channels in the short-wave infrared (940 …

Data-Driven Qoe Inference For Htttp Adaptive Streaming, Tisa Selma

Thesis/ Dissertation Defenses

In HTTP adaptive streaming, accurately inferring user Quality of Experience (QoE) remains challenging due to dynamic network conditions, content variations, end-to-end encryption, intrusive advertisement interruptions, and diverse user engagement behaviors. Conventional approaches, such as ITU-T P.1203, fall short in capturing real-time user perception, accounting for ad related disruptions, or adapting to model drift over time. This dissertation therefore aims to develop a multimodal face emotion recognition (FER) based inference model that predicts QoE under encryption and advertisement conditions while being interpretable, robust, resilient to drift, and highly accurate. To achieve these objectives, a unified framework is designed and implemented. The …

Defining The Opioid Crisis And The Limited Role Of The Criminal Justice System Resolving It, Julie A. Warren

University of Memphis Law Review

No abstract provided.

Effect Of Temperature On The Defensive And Predatory Behavior Of The Scorpion Hadrurus Obscurus (Scorpiones: Hadruridae), Zia Nisani, Megan Bennett, Audrey Enriquez, Mel Iniquez, Emilia Martinez Rios, Brooklyn Stone

Euscorpius

Scorpions employ their stinging mechanism both for defense and predation, and being ectothermic, temperature influences their physiology and behavior. As such, we hypothesized that temperature both affects defensive stinging and prey-capture behavior in scorpions. We tested the effects of body temperature on these behaviors in the desert hairy scorpion, Hadrurus obscurus Williams, 1970. In the first experiment, scorpions were placed in temperature-controlled chambers with either high (26-28°C) or low (21- 22°C) temperatures and probed to elicit a defensive sting. We recorded the reaction time and the number of probes needed to elicit a sting. In the second experiment, we observed …

Evolution Lower Limb Functional Asymmetry In Women's 400 M Hurdles From 1978-2022, Janusz Iskra, Wojciech Paśko, Paweł Gwiazdoń, Magdalena Chanas, Krzysztof Przednowek

Baltic Journal of Health and Physical Activity

Background: Functional asymmetry of the lower limbs in the technique of clearing 10 hurdles in the 400 m hurdles event was the subject of the study. Materials and methods: This study investigates the patterns of hurdle clearance, distinguishing between left and right lead legs by 196 female hurdlers competing in major championship events (including Olympic Games, World Championships, European Championships) from 1978 to 2022. The hurdlers were categorized into three groups based on competition periods: Group A (1978–2000), Group B (2001–2011), and Group C (2012–2022). The share of the left lead leg (assumed by most authors to be the lead …

Ai-Augmented Constitutionalism: Framing The Alliance Between Ai And Fundamental Rights In Comparative Perspective, Sergio Sulmicelli

Indian Journal of Law and Technology

The dominant academic literature on artificial intelligence and fundamental rights has been organised around a structuring premise: that AI systems pose a systemic threat to constitutional values, and that rights protection is a project of constraining and resisting automated decision-making. This article accepts and supports the empirical foundation of that literature. It does not accept that the framework is complete. This article proposes the concept of AI-augmented constitutionalism, defined as the deployment of artificial intelligence systems to strengthen the detection, enforcement, and access dimensions of fundamental rights, subject to a rule of law safeguards architecture. The concept inverts the dominant …

Level Of Nitrogen Fertilizer In Annual Winter Pasture (Oats-Ryegrass) And Summer Pasture (Millet): Effects On Milk Production, C J. Olivo, I L. Barreto, D A. Stiles

IGC Proceedings (1977-2023)

Two experiments were conducted with lactating Holstein cows to study the effects of different levels of nitrogen fertilizer (urea) on annual pasture: experiment 1, oats (Avena byzantina K. Koch) and ryegrass (Lolium multiflorum Lam.); experiment 2, millet (Pennisetum americanum (L.] Leche). Base fertilizer (8-28-18) was applied, and at the five-leaf stage three levels of nitrogen (N) (75, 150, and 225 kg/ha) were applied. The millet pasture followed the oat + ryegrass pasture, with the N treatments being maintained in the same areas. Two ha were planted for each treatment (total, 6 ha). In experiment 1, twelve lactating cows were randomly …

Effect Of Sheep And Cattle Grazing On A Mixed Pasture Of Perennial Ryegrass, Kikuyu, And White Clover, G J. Goold

IGC Proceedings (1977-2023)

Mixed pastlkes of perennial ryegrass (Lolium perenne L. ), kikuyugrass (Pennisetum clandestinum Hochst. ), and white clover (Trifolium repens L.) are commonly found within warm-zone areas of New Zealand but are frequently disliked because of prob­lems associated with kikuyugrass dominance. A grazing experiment was conducted to provide basic information on the response of such swards to grazing by cattle and sheep. The pastures were rotationally grazed with young sheep or cattle at two stocking levels each year from 1970 to 1975, with stocking rates adjusted twice yearly according to seasonal pasture growth. The pastures grazed by cattle …

A Comparative Evaluation Of Six Ryegrass Cultivars Under Grazing And Conservation Managements, M Ryan

IGC Proceedings (1977-2023)

Meat and dairy products command overriding importance in the Irish agricultural economy. They are derived primarily from Irish grasslands, which occupy 89% of the arable land area. Use of improved grass cultivars is probably the best means of increasing grassland output once the basics, optimal fertilizer use, and high stocking rates have been met. Objective identification of superior cultivars is the responsibility of state agencies. A recommended list, published annually in Ireland, presently contains 47 ryegrass (Lolium perenne) cultivars. There is some doubt, however, that results from small-plot cutting trials can be extrapolated to equivalent performance by grazing …

Dynamics Of Herbage Growth And Senescence In A Mixed-Species Temperate Sward Continuously Grazed By Sheep, J S. Bircham, J Hodgson

IGC Proceedings (1977-2023)

Four perennial ryegrass (Lolium perenne L.)-Poa annua L.-white clover (Trifolium repens L.) swards with herbage mass rang­ing from 500 to 1,700 kg organic matter (OM)/ha were established and maintained in as near a steady state as possible by con­tinuous but variahle stocking with sheep in order to study the influence of herbage mass on rates of herbage growth (G), senescence (S), and net production (NP), and on species balance. Estimates ofG, S, and NP were derived from measurements on individual grass tillers and clover stolon growth sites. The mean contributions to total G were 54, 20, and 4 ( ± …