Open Access. Powered by Scholars. Published by Universities.®

Digital Commons Network™

Open Access. Powered by Scholars. Published by Universities.®

Discipline
Institution
Keyword
Publication Year
Publication
Publication Type
File Type

Articles 8701 - 8730 of 240071

Full-Text Articles in Entire DC Network

Let's Bee Pragmatic: The Economic Case For Neonicotinoid Regulation In Conservative States, Annie Rosenstein Oct 2025

Let's Bee Pragmatic: The Economic Case For Neonicotinoid Regulation In Conservative States, Annie Rosenstein

William & Mary Environmental Law and Policy Review

The importance of bees in our ecosystem and to our food system in the United States cannot be overstated. In fact, 35% of global crop production depends on bees and other pollinating insects. Pollinators not only influence the production of many foods that we hold dear and rely on, such as apples, chocolate, potatoes, and coffee, but also influence the quality of these products.

Currently, the most insidious threat against bees in the United States is neonicotinoid pesticides (neonics). While neonics are effective at killing the target populations of beetles, aphids, and flies, they are equally effective at killing pollinators, …


Barriers And Best Practices In Diversity, Equity, And Inclusion (Dei) Initiatives: A Case Study From The United States Aerospace And Defense Industry, Jeremy A. Bailey Oct 2025

Barriers And Best Practices In Diversity, Equity, And Inclusion (Dei) Initiatives: A Case Study From The United States Aerospace And Defense Industry, Jeremy A. Bailey

Doctoral Dissertations and Master's Theses

The main objective of this study was to unpack the barriers around diversity, equity, and inclusion (DEI) initiatives, and then provide best practices to improve DEI efforts in the aerospace and defense (A&D) industry. There has been a multitude of research conducted on DEI in the past few years. However, very little research has focused on DEI practices in the A&D industry. This case study focused on one large company in this industry to explore and understand various aspects of DEI initiative implementation. As organizations strive to meet industry and client objectives, as well as address employee needs, two research …


Saudi Clinical Practice Guidelines For Management Of Diabetic Kidney Disease In Adults, Khalid I. Almatham, Hajer Y. Almudaiheem, Waleed A. Alhazzani, Haifa F. Alotaibi, Saad S. Alobaili, Mohammed H. Tawhari, Saud N. Alsifri, Rehab B. Albakr, Mohammed N. Alomi, Khalidah A. Alenzi, Bedor A. Al-Omari, Ahmed H. Al-Jedai Oct 2025

Saudi Clinical Practice Guidelines For Management Of Diabetic Kidney Disease In Adults, Khalid I. Almatham, Hajer Y. Almudaiheem, Waleed A. Alhazzani, Haifa F. Alotaibi, Saad S. Alobaili, Mohammed H. Tawhari, Saud N. Alsifri, Rehab B. Albakr, Mohammed N. Alomi, Khalidah A. Alenzi, Bedor A. Al-Omari, Ahmed H. Al-Jedai

Saudi Medical Journal

ABSTRACT Objectives: To develop evidence-based national guidelines incorporating recent advancements in clinical research and therapeutic strategies for the management of patients with diabetic kidney disease (DKD) in the Kingdom of Saudi Arabia (KSA). Methods: We developed the guidelines using the GRADE methodology and a multidisciplinary expert panel comprising nephrologists, endocrinologists, clinical pharmacists, and methodologists across KSA. We conducted a systematic literature review of studies published between 2014–2024. The evidence certainty was evaluated across 5 domains using GRADEpro and categorized into 4 levels: “high”, “moderate”, “low”, and “very low”. Recommendations were formulated based on the benefit-risk ratio, evidence quality, and expert …


Global Transfusion Practices In Septic Patients In The Intensive Care Unit: Insights From The Input-Study Sub-Analysis, Vincent Kurucz, Andrew Flint, Alexis Poole, Merijn Reuland, Claudia Oord, Caroline Schaap, Jan Bakker, Maurizio Cecconi, Aarne Feldheiser, Marcus Lance Oct 2025

Global Transfusion Practices In Septic Patients In The Intensive Care Unit: Insights From The Input-Study Sub-Analysis, Vincent Kurucz, Andrew Flint, Alexis Poole, Merijn Reuland, Claudia Oord, Caroline Schaap, Jan Bakker, Maurizio Cecconi, Aarne Feldheiser, Marcus Lance

Anaesthesiology, East Africa

Background Transfusion practices among intensive care unit (ICU) patients with sepsis vary widely. While restrictive hemoglobin thresholds for red blood cell (RBC) transfusion are well studied, the indications and thresholds for platelet and plasma transfusions remain uncertain.

Methods We performed a sepsis-specific sub-analysis of the International Point Prevalence Study of Intensive Care Unit Transfusion Practices, a prospective, multicenter, observational study capturing all adult ICU admissions during four pre-scheduled weeks between March 2019 and October 2022. Patients admitted with sepsis or septic shock, or who developed sepsis during their ICU stay, were included. We recorded demographics, daily laboratory values, and transfusion …


College Of Natural Sciences Newsletter, Fall 2025, College Of Natural Sciences Oct 2025

College Of Natural Sciences Newsletter, Fall 2025, College Of Natural Sciences

College of Natural Sciences Newsletters and Reports

P.1 Dean's Message from Dr. Sen Subramanian
P.2 Student Spotlights
P.3 One Day for STATE
P.4 Fun Filming with Jack
P.5 Germanium Studies
P.6 Research Expenditures
P.8 Increased Enrollment
P.9 Faculty Recognition
P.11 Scoops & Smiles


Loma Linda Nurse - Vol. 34, Loma Linda University School Of Nursing Oct 2025

Loma Linda Nurse - Vol. 34, Loma Linda University School Of Nursing

Loma Linda Nurse

FEATURES

4 | Jordan Robison Profile

6 | LLUSN Mission Service— A Living Legacy

10 | Steps to a New School

12 | Entry Level Master’s at Murietta

LLUSN HIGHLIGHTS

14-21 | ALUMNI NEWS

22-27 | ACADEMICS

28-33 | HOMECOMING

34-37 | FACULTY UPDATES


In Defense Of The Care Economy, Emily Daniel Oct 2025

In Defense Of The Care Economy, Emily Daniel

Araneum: Richmond Journal of American & Global Affairs

Women are burdened with caregiving, yet their contributions are frequently undervalued and undercompensated. During the nineteenth century, women worldwide gained the right to vote, access to education, marital freedom, and the right to join the workforce. Yet today, they contribute significantly to unpaid or low-paying care work, tending to domestic responsibilities while participating in the labor force. These roles are motivated by moral or altruistic values rather than financial compensation and provide for needs in childhood, old age, and sickness. With women doing an average of 2.5 times more unpaid domestic work than men, they are at the heart of …


Characterization Of Pigeonpea As An Alternate Summer Forage Crop In Virginia, Satya S. S. Narina, Glenn Chappell Iii, Harbans L. Bhardwaj Oct 2025

Characterization Of Pigeonpea As An Alternate Summer Forage Crop In Virginia, Satya S. S. Narina, Glenn Chappell Iii, Harbans L. Bhardwaj

Virginia Journal of Science

Pigeonpea (Cajanus cajan L.), a major multifunctional food legume crop valued globally, contributes to food security by supplying protein-rich grain for human consumption and provides nutrient-rich biomass for livestock feeding across diverse production systems. However, little is known about its forage potential in the mid-Atlantic region of the United States. In 2009 and 2010, four cultivars (GA-1, GA-2, W-1, and W-3) were evaluated in a split-plot design with three intra-row plant populations (2, 4, or 6 plants per 0.3 m row) and three planting dates (May, June, and July). Forage yield, crude protein, minerals, and other nutritional traits were …


Finding Aid For University Of Mississippi Small Manuscripts(Mum01771) Oct 2025

Finding Aid For University Of Mississippi Small Manuscripts(Mum01771)

Archives & Special Collections: Finding Aids (alphabetical)

The collection contains items related to the University of Mississippi. The collection is arranged by subject.


Diabetes-Related Foot Complications And Socioeconomic Influences Among Hispanic Males In South Texas: A Scoping Review, Mariana J. Rodriguez, Demian Rodriguez, Amanda Killeen Oct 2025

Diabetes-Related Foot Complications And Socioeconomic Influences Among Hispanic Males In South Texas: A Scoping Review, Mariana J. Rodriguez, Demian Rodriguez, Amanda Killeen

School of Podiatric Medicine Publications

Introduction: Diabetes mellitus is the 7th leading cause of death in the U.S. and 6th in Texas. South Texas counties have higher diabetes rates than state and national averages. This complex, progressive disease affects multiple body systems and can lead to serious complications, especially in the lower extremities. Uncontrolled diabetes is often associated with diabetic foot ulcers (DFU), foot infections, and lower extremity amputations (LEA). South Texas, predominantly Hispanic American, is disproportionately affected. This demographic faces clinical barriers due to a lack of cultural understanding, highlighting the need for culturally sensitive healthcare workers such as promotoras. This study aimed to …


Arcadia Magazine, 2025-10 Oct 2025

Arcadia Magazine, 2025-10

Alumni Magazine

No abstract provided.


The Role Of The Global Financial Reporting Standards (Gri) In Enhancing Accounting Disclosure Of Sustainability In Iraqi Companies, Adnan Yasir Mohamaad Oct 2025

The Role Of The Global Financial Reporting Standards (Gri) In Enhancing Accounting Disclosure Of Sustainability In Iraqi Companies, Adnan Yasir Mohamaad

Journal of Economics and Administrative Sciences

The research aims to identify the role of Global Financial Reporting Standards (GRI) in enhancing accounting disclosure of sustainability in Iraqi companies, by relying on the four global financial reporting standards, which include: the economic axis (GRI 200), the environmental axis (GRI 300), the social axis (GRI 400 and the general indicators (GRI 102),  the research sample represented an interantional companies listed on the Iraq Stock Exchange, namely: Al-Khatam Company and Asiacell Company. In order to analyse the results, the content and disclosure survey of the data and reports published in the Iraq Stock Exchange was employed. The accounting disclosure …


Une Com Research And Scholarship Fall Forum October 2025, Une Com Research & Scholarship Oct 2025

Une Com Research And Scholarship Fall Forum October 2025, Une Com Research & Scholarship

Osteopathic Student Research Symposia

Program including abstracts from the University of New England College of Osteopathic Medicine’s 2025 Research and Scholarship Fall Forum.

Supplemental content: List of award winners.


Bone Mineral Density Of Willow Ptarmigan (Lagopus Lagopus) As A Potential Taphonomic Factor In Skeletal Part Attrition, Frank J. Dirrigl Jr., Samuel R. Buchanan Oct 2025

Bone Mineral Density Of Willow Ptarmigan (Lagopus Lagopus) As A Potential Taphonomic Factor In Skeletal Part Attrition, Frank J. Dirrigl Jr., Samuel R. Buchanan

School of Integrative Biological & Chemical Sciences Faculty Publications

Agents of taphonomy can bias skeletal parts and the frequency of bones in archaeological sites. An important factor to consider is the possible effect of bone density-mediated attrition on archaeornithological assemblages. We scanned willow ptarmigan (Lagopus lagopus) specimens using a Lunar iDXA and an enCcore small animal body add-on to develop a rank-order scheme based on the volumetric bone mineral density (vBMD) of skeletal parts. Our results identified the tibiotarsus and femur to be the least dense bones, while carpometacarpus, 3rd digit, and coracoid were the densest. This novel scheme allowed us to evaluate a sample of 22 …


Beyond The Plate: Equity-Focused Solutions To Childhood Nutrition And Family Well-Being, Lynn Brann, Rachel Razza, Xiafei Wang, Kristen Davis Oct 2025

Beyond The Plate: Equity-Focused Solutions To Childhood Nutrition And Family Well-Being, Lynn Brann, Rachel Razza, Xiafei Wang, Kristen Davis

The Lender Center for Social Justice

Food insecurity continues to affect millions of U.S. families, with nearly one in ten households with children struggling to consistently access nutritious food. This policy brief explores equity-focused solutions to childhood nutrition and family well-being, drawing on insights from parents of young children in low-income, culturally diverse households in Syracuse, New York. Through a participatory action research approach, parents shared their experiences, challenges, and hopes for improving their children’s eating habits and preserving cultural food traditions. The findings reveal that while parents are committed to providing healthy meals, systemic barriers such as financial constraints, limited access to culturally relevant foods, …


Combating Obesity: Creating A Comprehensive Wellness Plan For Uninsured & Low-Income Populations, Kayla C. Berrios Oct 2025

Combating Obesity: Creating A Comprehensive Wellness Plan For Uninsured & Low-Income Populations, Kayla C. Berrios

Doctor of Nursing Practice Scholarly Projects

Aim: The aim of this project was to research the specific barriers encountered by obese patients that are low-income and uninsured. The goal of this data collection was to inform the stakeholders involved in creating a comprehensive wellness plan for obese patients.

Background: The staff at Good Neighbor Clinic have struggled to support their support their obese patients with weight reduction. Many of the ailments that patients seek care for correlate to their obesity. Health promotion in this community clinic needs a more comprehensive program to support patients during their weight loss experience, providing support and resources to allow for …


Exploring Barriers To Patient Care In A South Carolina Free Clinic, Jonathan G. Green Oct 2025

Exploring Barriers To Patient Care In A South Carolina Free Clinic, Jonathan G. Green

Doctor of Nursing Practice Scholarly Projects

Access to healthcare remains a persistent challenge for medically underserved populations who rely on free medical clinics for primary care services, particularly in non-Medicaid expansion states such as South Carolina. Free clinics serve as critical safety-net providers, yet patients frequently encounter barriers that limit access, continuity, and quality of care. The purpose of this Doctor of Nursing Practice (DNP) project was to explore and identify the structural, social, and interprofessional barriers to patient care within a South Carolina free medical clinic to inform targeted, evidence-based interventions. A mixed-methods needs assessment design was used, combining a retrospective chart review of forty …


Empowering Mothers: A Digital Intervention For Perinatal Mental Wellness, Morgan Edmunds Oct 2025

Empowering Mothers: A Digital Intervention For Perinatal Mental Wellness, Morgan Edmunds

Doctor of Nursing Practice Scholarly Projects

Aim: The aim of this project was to develop a smartphone application prototype for peripartum mental health. The goal of this application was to enhance access to education and quality mental health care.

Background: Currently, in the United States, peripartum mental health conditions are the leading cause of maternal morbidity and mortality (The Joint Commission, 2023). There is a gap in education, screening, and treatment for peripartum mental health due to distrust and a lack of resources, including a lack of mental health providers (Dossette et al., 2024; Feldman & Perret, 2023). Therefore, there is a significant number of women …


Predictive Model Of School Dropout In Higher Education Through Learning Analytics With Neutrosophic Plithogenic Hypotheses, David Núñez, Purificación Galindo-Villardón Oct 2025

Predictive Model Of School Dropout In Higher Education Through Learning Analytics With Neutrosophic Plithogenic Hypotheses, David Núñez, Purificación Galindo-Villardón

Neutrosophic Sets and Systems

Higher education dropout rates are an international problem, as many people abandon their studies, especially in the early years. This problem affects institutions, causing significant losses. In this context, it is essential to consider methods that allow for predicting dropout rates and taking rapid and effective measures. Objective: The main objective is to analyze prediction models using Learning Analytics, integrating neutrosophic plithogenic hypotheses, to identify early the risk of dropout in higher education. This provides institutions with useful tools to implement actions that help retain more students, considering uncertainty and complex interactions between academic and non-academic factors. Methodology: The method …


Breastfeeding In Indonesia On The Rise, But Mothers Need More Support Oct 2025

Breastfeeding In Indonesia On The Rise, But Mothers Need More Support

Saudi Medical Journal

No abstract provided.


Harding Magazine Fall 2025 (Vol. 33, No. 1), Harding University Oct 2025

Harding Magazine Fall 2025 (Vol. 33, No. 1), Harding University

Harding Magazines

Publication distributed to alumni and friends of the community


Care As The Primary Motivation In Home Birthing Among Mothers In Panukulan, Quezon, Leslie A. Lopez, Marie Angelie Molina Oct 2025

Care As The Primary Motivation In Home Birthing Among Mothers In Panukulan, Quezon, Leslie A. Lopez, Marie Angelie Molina

Institute of Philippine Culture (IPC)

This qualitative study examines how women in Panukulan, Quezon, a GIDA municipality, make decisions regarding childbirth in light of national and municipal policies that promote institutional delivery and discourage home births. Using the Theory of Planned Behavior as an analytical framework, the study analyzes maternal intrapartum health-seeking behavior (HSB) through the following components: a) sociocultural and institutional context, b) intention formation based on attitudes toward facility and home birthing, perceptions of subjective norms, and perceived behavioral control, and c) actual behavior. Findings reveal that while facility births are widely recognized for their clinical safety, women’s preferences for specific behaviors are …


Adipose Tissue Estrogen Receptor-Alpha Overexpression Ameliorates High-Fat Diet–Induced Adipose Tissue Inflammation, Marion C. Hope, Christian A. Unger, M Chase Kettering, Cassidy E. Socia, Ahmed K. Aladhami, Barton C. Rice, Darya S. Niamira, Ben P. Wiznitzer, Diego Altomare Ph.D., William E. Cotham, Reilly T. Enos Oct 2025

Adipose Tissue Estrogen Receptor-Alpha Overexpression Ameliorates High-Fat Diet–Induced Adipose Tissue Inflammation, Marion C. Hope, Christian A. Unger, M Chase Kettering, Cassidy E. Socia, Ahmed K. Aladhami, Barton C. Rice, Darya S. Niamira, Ben P. Wiznitzer, Diego Altomare Ph.D., William E. Cotham, Reilly T. Enos

Faculty Publications

Context

We created an innovative mouse model that enables inducible overexpression of estrogen receptor-alpha (ERα), specifically in adipose tissue (Adipo-ERα↑). Objective

We aimed to investigate how elevated Adipo-ERα↑ influences the development of high-fat diet (HFD)-induced obesity in both male and female mice. Methods

Male and female Adipo-ERα↑ mice and littermate controls were fed a low-fat diet (LFD) or HFD for 13 weeks. Adipo-ERα↑ was induced at the initiation of dietary treatment. Body morphology and composition, hepatic lipid accumulation, glucose tolerance, fasting insulin concentrations, and adipose tissue mRNA profiling were assessed. Liquid chromatography–mass spectrometry was used to determine circulating and adipose …


Hooks For Four-Dimensional Ecology Education (4dee) Teaching With Differing Audiences Of Nonmajors, Sara E. Scanga, Vikki L. Rodgers, Loren B. Byrne, Justin R. St. Juliana, Jon M. Honea, Erica S. Tietjen, George Middendorf Oct 2025

Hooks For Four-Dimensional Ecology Education (4dee) Teaching With Differing Audiences Of Nonmajors, Sara E. Scanga, Vikki L. Rodgers, Loren B. Byrne, Justin R. St. Juliana, Jon M. Honea, Erica S. Tietjen, George Middendorf

Arts & Sciences Faculty Publications

Nonmajors (i.e., undergraduate students not majoring in the natural sciences) constitute a majority of United States college graduates and are a large potential audience for courses with ecology content. However, nonmajors may be unmotivated to learn about ecology because they perceive it to be uninteresting and irrelevant to their everyday lives or career goals. Although the Four-Dimensional Ecology Education (4DEE) framework can be adapted for nonmajors courses as a starting point to improve student engagement, we suggest that nonmajors ecology instructors also use ecology hooks as effective gateways to 4DEE that will motivate and deepen student learning. Selecting and developing …


A Scoping Review Of Oral Feeding Skill Development In Typically Developing Children Part Ii: Exploring Variability In Oral Feeding Skill Descriptions, Amy Delaney, Anna Flatt, Hannah Koepp, Alissa Fial, Katherine C. Hustad Oct 2025

A Scoping Review Of Oral Feeding Skill Development In Typically Developing Children Part Ii: Exploring Variability In Oral Feeding Skill Descriptions, Amy Delaney, Anna Flatt, Hannah Koepp, Alissa Fial, Katherine C. Hustad

Speech Pathology and Audiology Faculty Research and Publications

Purpose:

This scoping review is the second in a two-part series that aims to synthesize the literature on oral feeding skills development and to create a classification system of observable skills. Building on the findings from Part 1, this article compiles and analyzes the types of feeding skills reported across studies and proposes a framework for standardizing terminology.

Method:

The review followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews guidelines. Of the 14 studies identified in Part 1 that focused on feeding skill development, 11 included unique skill descriptions. These skills were coded and …


Adipokines Mediate Fat-To-Ovary Communication To Regulate Oogenesis, Adipocyte Size, And Lipid Storage In Drosophila Melanogaster, Chad Herbert Simmons Oct 2025

Adipokines Mediate Fat-To-Ovary Communication To Regulate Oogenesis, Adipocyte Size, And Lipid Storage In Drosophila Melanogaster, Chad Herbert Simmons

Theses and Dissertations

Humans have complex signaling pathways that allow them to store and expend energy based on nutritional quality and availability. Inter-organ signaling is used to communicate nutrient availability between organs based on nutritional needs and the rate of cellular division. Our main overarching question is to investigate how fat-derived signals affect adipocyte morphology and the maintenance of stem cells in the ovary. While signaling pathways, like insulin and mTOR, and some adipokines that are involved in inter-organ nutrient sensing have been identified, the exact nutrient reliant mechanisms of stem cell maintenance are not completely understood. Using Drosophila melanogaster as a model, …


Approaches To Reduce The Impact Of Stroke In Gulf Cooperation Council Nations, Muath A. Alammar Oct 2025

Approaches To Reduce The Impact Of Stroke In Gulf Cooperation Council Nations, Muath A. Alammar

Saudi Medical Journal

No abstract provided.


Phase Iv Clinical Trials For The Treatment Of Non-Small Cell Lung Carcinoma (Nsclc): A Systemic Review From 2020-2025, Yousif A. Kariri, Mohammed H. Alqasmi, Bijad S. Alqahtani Oct 2025

Phase Iv Clinical Trials For The Treatment Of Non-Small Cell Lung Carcinoma (Nsclc): A Systemic Review From 2020-2025, Yousif A. Kariri, Mohammed H. Alqasmi, Bijad S. Alqahtani

Saudi Medical Journal

ABSTRACT Objective: To evaluate and provide evidence on drugs investigated in completed phase IV clinical trials for adult non-small cell lung carcinoma (NSCLC) therapy, primarily focusing on treatment objectives and adverse effects. Methods: Clinical research studies from January 2020 to January 2025 were systematically reviewed using the “ClinicalTrials.gov” database. The inclusion criteria focused on publicly available, relevant, and completed Phase IV studies limited to “Clinicaltrials.gov”, while those not meeting these specifications were excluded. As of 3 January 2025, a total of 7,541 Phase IV clinical trials were available on “ClinicalTrials.gov”, of which 121 were related to NSCLC. Results: Six of …


Stroke Incidence, Mortality And Disability-Adjusted Life Years (Dalys) Trends In Association With Air Pollution, Dietary And Metabolic Risk Factors In Gulf Cooperation Council Countries: Global Burden Of Disease Data Based Analysis 1990-2021, Bandar N. Aljafen, Anusha S. Meo, N. Shaikh, Sultan A. Meo Oct 2025

Stroke Incidence, Mortality And Disability-Adjusted Life Years (Dalys) Trends In Association With Air Pollution, Dietary And Metabolic Risk Factors In Gulf Cooperation Council Countries: Global Burden Of Disease Data Based Analysis 1990-2021, Bandar N. Aljafen, Anusha S. Meo, N. Shaikh, Sultan A. Meo

Saudi Medical Journal

ABSTRACT Objectives: To identify the primary risk factors contributing to stroke incidents and deaths, analyzing the trends and changes in regional stroke statistics between 1990 and 2021 in the Gulf Cooperation Council (GCC) countries. Methods: This longitudinal time trend study was conducted in the Department of Physiology, College of Medicine, King Saud University, Riyadh, Saudi Arabia, from June to August 2024. The data were recorded from the Institute for Health Metrics and Evaluation (IHME) and the Global Burden of Diseases (GBD) datasets. The incidence, mortality, and disability-adjusted life year (DALY) rates of stroke in the GCC countries, Bahrain, Kuwait, Oman, …


Characterization And Management Of Pain Across Phases Of Intraosseous Infusion In Emergency Department Patients With Non-Cardiac Arrest, Aiping Shi, Juan Chen, Xiaowei He, Chunyan Chen, Ming Sun, Wei Li, Wenxia Xu, Wei Yang, Xiaoqin Han Oct 2025

Characterization And Management Of Pain Across Phases Of Intraosseous Infusion In Emergency Department Patients With Non-Cardiac Arrest, Aiping Shi, Juan Chen, Xiaowei He, Chunyan Chen, Ming Sun, Wei Li, Wenxia Xu, Wei Yang, Xiaoqin Han

Saudi Medical Journal

ABSTRACT Objectives: To identify risk factors for moderate-to-severe pain during intraosseous infusion (IOI) in non-cardiac arrest patients in the emergency department (ED). Secondary aims include evaluating pain trajectory across procedural stages and assessing the efficacy of a personalized pain management strategy. Methods: This mixed-methods study analyzed 220 ED patients undergoing IOI (150 retrospective, 70 prospective). The prospective cohort was randomized to standard care (n=35) or personalized pain management (n=35). Pain was quantified using the numeric rating scale (NRS) and critical-care pain observation tool (CPOT). Results: During puncture, 35.33% (53/150) reported no/mild pain. Pain severity peaked during flushing, with 73.33% (110/150) …