Digital Commons Network^™

Deep Learning Auto-Segmentation Of Cervical Skeletal Muscle For Sarcopenia Analysis In Patients With Head And Neck Cancer, Mohamed A Naser, Kareem A Wahid, Aaron J Grossberg, Brennan Olson, Rishab Jain, Dina El-Habashy, Cem Dede, Vivian Salama, Moamen Abobakr, Abdallah S R Mohamed, Renjie He, Joel Jaskari, Jaakko Sahlsten, Kimmo Kaski, Clifton D Fuller

Faculty, Staff and Student Publications

Background/purpose: Sarcopenia is a prognostic factor in patients with head and neck cancer (HNC). Sarcopenia can be determined using the skeletal muscle index (SMI) calculated from cervical neck skeletal muscle (SM) segmentations. However, SM segmentation requires manual input, which is time-consuming and variable. Therefore, we developed a fully-automated approach to segment cervical vertebra SM.

Materials/methods: 390 HNC patients with contrast-enhanced CT scans were utilized (300-training, 90-testing). Ground-truth single-slice SM segmentations at the C3 vertebra were manually generated. A multi-stage deep learning pipeline was developed, where a 3D ResUNet auto-segmented the C3 section (33 mm window), the middle slice of the …

High-Resolution Metabolomics Of Exposure To Tobacco Smoke During Pregnancy And Adverse Birth Outcomes In The Atlanta African American Maternal-Child Cohort, Youran Tan, Dana Boyd Barr, P Barry Ryan, Veronika Fedirko, Jeremy A Sarnat, Audrey J Gaskins, Che-Jung Chang, Ziyin Tang, Carmen J Marsit, Elizabeth J Corwin, Dean P Jones, Anne L Dunlop, Donghai Liang

Faculty, Staff and Student Publications

Exposure to tobacco smoke during pregnancy has been associated with a series of adverse reproductive outcomes; however, the underlying molecular mechanisms are not well-established. We conducted an untargeted metabolome-wide association study to identify the metabolic perturbations and molecular mechanisms underlying the association between cotinine, a widely used biomarker of tobacco exposure, and adverse birth outcomes. We collected early and late pregnancy urine samples for cotinine measurement and serum samples for high-resolution metabolomics (HRM) profiling from 105 pregnant women from the Atlanta African American Maternal-Child cohort (2014-2016). Maternal metabolome perturbations mediating prenatal tobacco smoke exposure and adverse birth outcomes were assessed …

Establishment And Validation Of Pre-Therapy Cervical Vertebrae Muscle Quantification As A Prognostic Marker Of Sarcopenia In Patients With Head And Neck Cancer, Brennan Olson, Jared Edwards, Catherine Degnin, Nicole Santucci, Michelle Buncke, Jeffrey Hu, Yiyi Chen, Clifton D Fuller, Mathew Geltzeiler, Aaron J Grossberg, Daniel Clayburgh

Faculty, Staff and Student Publications

Background: Sarcopenia is prognostic for survival in patients with head and neck cancer (HNC). However, identification of this high-risk feature remains challenging without computed tomography (CT) imaging of the abdomen or thorax. Herein, we establish sarcopenia thresholds at the C3 level and determine if C3 sarcopenia is associated with survival in patients with HNC.

Methods: This retrospective cohort study was conducted in consecutive patients with a squamous cell carcinoma of the head and neck with cross-sectional abdominal or neck imaging within 60 days prior to treatment. Measurement of cross-sectional muscle area at L3 and C3 levels was performed from CT …

Cancer Treatment-Induced Nad+ Depletion In Premature Senescence And Late Cardiovascular Complications, Priyanka Banerjee, Elizabeth A Olmsted-Davis, Anita Deswal, Minh Th Nguyen, Efstratios Koutroumpakis, Nicholas L Palaskas, Steven H Lin, Sivareddy Kotla, Cielito Reyes-Gibby, Sai-Ching J Yeung, Syed Wamique Yusuf, Momoko Yoshimoto, Michihiro Kobayashi, Bing Yu, Keri Schadler, Joerg Herrmann, John P Cooke, Abhishek Jain, Eduardo Chini, Nhat-Tu Le, Jun-Ichi Abe

Faculty, Staff and Student Publications

Numerous studies have revealed the critical role of premature senescence induced by various cancer treatment modalities in the pathogenesis of aging-related diseases. Senescence-associated secretory phenotype (SASP) can be induced by telomere dysfunction. Telomeric DNA damage response induced by some cancer treatments can persist for months, possibly accounting for long-term sequelae of cancer treatments. Telomeric DNA damage-induced mitochondrial dysfunction and increased reactive oxygen species production are hallmarks of premature senescence. Recently, we reported that the nucleus-mitochondria positive feedback loop formed by p90 ribosomal S6 kinase (p90RSK) and phosphorylation of S496 on ERK5 (a unique member of the mitogen-activated protein kinase family …

Serum Gamma Glutamyltransferase (Ggt) In Coronary Artery Disease: Exploring The Asian Indian Connection, Kunal K Singh, Aditya Kapoor, Roopali Khanna, Ankit Sahu, Vishwas Kapoor, Sudeep Kumar, Naveen Garg, Satyendra Tewari, Pravin Goel

Faculty, Staff and Student Publications

BACKGROUND: There is a need to identify novel markers for CAD, independent of traditional CV risk factors. One of these is gamma-glutamyl transferase (GGT), a marker of increased oxidative stress. Given the high prevalence of CAD in Asian Indians, the link of GGT and CAD in them needs to be studied.

AIM: To assess GGT in patients with angiographically documented CAD.

METHODS AND RESULTS: Two hundred patients aged 58.1 ± 9.95 years, 73% males, hypertension 56%, diabetes 40% were included. Mean GGT was 63.6 ± 44.33 (10–269 U/L). The levels of GGT progressively increased in those with single/double or triple-vessel …

Emerging Current Trends And Research Focus Related To Pancreatic Cancer Metabolism: A Bibliometric And Visualized Analysis, Qian Shen, Chuanlong Zhang, Xiaochen Jiang, Junchen Li, Fudong Liu, Xiyuan Zhang, Ge'er En, Bo Pang

Faculty, Staff and Student Publications

BACKGROUND: As a malignant digestive system tumor, pancreatic cancer has unique metabolic characteristics. In recent years, the study of pancreatic cancer metabolism is in full swing, which provides a new direction for the treatment of pancreatic cancer patients. However, there is no systematic report of pancreatic cancer metabolism. In this paper, bibliometrics and visualization methods were used to analyze the number of publications, countries/regions, authors, institutions, journals, co-cited references, and keywords of pancreatic cancer metabolism articles, to summarize the research trends and predict research hotspots.

METHODS: We searched, screened and downloaded articles on pancreatic cancer metabolism through the Web of …

Factors That Affect The Rate Of Preterm Birth: An Examination Of The Inter-Related Impacts Of Social Determinants, Behavior And Physical Health Status, Krystal Michelle Hunter

Dissertations

The work seeks to examine the factors that have significant relationships to the rate of preterm birth (PTB) along with its cost to society.

There are four papers within this work. This purpose of the first paper is to measure the impact that healthy behaviors have on the rate of PTB when modeled with other factors like household demographics, community deprivation, chronic disease and mental health. This work finds that positive health behaviors has a negative relationship with PTB. The interaction between body mass index (BMI) and social class and its relationship to PTB is examined in the second paper. …

Penggunaan Goal Programming Dalam Perencanaan Menu Untuk Lansia Penderita Hipertensi, Diana Islamiyati, Dwi Lestari, Nur Insani

PYTHAGORAS : Jurnal Matematika dan Pendidikan Matematika

Penelitian ini bertujuan untuk membangun suatu model goal programming untuk mengoptimalkan perencanaan menu harian lansia penderita hipertensi. Fungsi tujuan model ini yaitu untuk memaksimumkan kandungan gizi makanan lansia sesuai Angka Kecukupan Gizi (AKG), meminimumkan biaya pangan, memaksimumkan kuantitas pangan, dan meminimumkan konsumsi pangan yang mengandung natrium. Berdasarkan eksperimen komputasi yang dilakukan dengan menerapkan model weighted goal programming ini, dihasilkan solusi optimal kebutuhan gizi lansia penderita hipertensi yang sesuai dengan AKG. Adapun perencanaan optimal menu makanan untuk lima hari yaitu terdiri dari 12 jenis pangan dengan pengeluaran biaya sebesar Rp 11.236,- untuk hari pertama, 13 jenis pangan dengan pengeluaran biaya …

The Determinant Factor Of The Mother's Ability To Choose Healthy Food, Nurul Ridhi Utami, Endang Mulyatiningsih

Jurnal Pendidikan Vokasi

This study aims to reveal: 1.) The size of the capital city in consuming healthy food; 2.) Selection of healthy food between working and non-working mothers; 3.) Choosing mothers in healthy food between families with a budget for food costs per person per day; and 4.) Choosing mothers in healthy food according to the number of family members. This research is a quantitative survey. The population was the research of PKK mothers in Delta Pawan and Benua Kayong districts, Ketapang, West Kalimantan. Samples of 90 can be responsive using cluster area random sampling. Validity is based on content validity. The …

A Critical Study On Female Roles In Television Commercials Of Bangladesh, Moriom Begum Mim, Maliha Tabassum

Informasi

Media representation of female gender roles in advertising are relentlessly contested themes in a traditional society. Stereotypical representation not only limits the socially accepted traditional roles of gender, but also has an impact on how people perceive women. This study has focused on how women characters are constructed in order to understand reflection of stereotypical gender norms in Bangladeshi television commercials. Stuart Hall's representation theory has adapted as the framework for conceptualizing the context of this study and scrutinizing the data. Using qualitative and quantitative methods, this paper has explored how such representations constitute unequal gender identities, traditional norms and …

Annual Report 2020 - 2021, Houston Academy Of Medicine - Texas Medical Center Library

Annual Reports: 1943 - Present

This file contains the Annual Report for the library from 2020-2021.

Thinking In The Global South — Reflections On Anti-Vaxxers As An Instance Of Global Alterity, Raul Pertierra

Social Transformations Journal of the Global South

Excerpt: The COVID-19 pandemic has brought to light several features of the present state of globality. In many countries, objections against vaccination have attracted media prominence. Although reasons for this resistance may differ from one country to another, there seems to be a common thread linking them globally. This paper examines this thread and explores its relationship to conditions underlying modernity. As some have argued (e.g., Latour 2014, Luhmann 1998), modernity is not an explanatory concept but a category that allows us to label a complex reality, which includes internal contradictions (e.g., a society of universal levelling whose mechanism effaces …

The Difference In Nutrition Intake Adequacy Amonginstitutionalized Elderly Residents With And Without Sarcopeniaat Nursing Homes In Bandung, West Java, Delia Anastasia Tirtadjaja, Muhamad Apandi, Lazuardhi Dwipa

Jurnal Penyakit Dalam Indonesia

Introduction. The changes in the elderly’s daily routine including dietary intake and nutritional pattern may cause them to be more susceptible to malnutrition. The changes also increase the risk of sarcopenia that may lead to poor health outcomes such as fall injury, fracture, hospitalization, disability, or even death. Sarcopenia is more likely to occur in a nursing home compared to community settings. This study aimed to determine the difference in nutrition intake adequacy between institutionalized elderly subjects with and without sarcopenia in Bandung, West Java. Methods. A cross-sectional study was held in Ciparay and Budi Istri Nursing Home, Bandung, West …

Correlation Between Polypharmacy And Length Of Stay Geriatric Patient In Mohammad Hoesin Palembang Hospital, Iswadi Tanzil, Nur Riviati, Irsan Saleh

Jurnal Penyakit Dalam Indonesia

Introduction. Geriatric patients have multipathological characteristics, low physiologic reserves, atypical clinical signs and symptoms, decreased functional status, and nutritional disturbances. This situation is a risk factor for polypharmacy. Polypharmacy is closely related to drug side effects, drug interactions, and patient compliance. Polypharmacy is thought to have a relationship with the length of stay in geriatric patients. The purpose of this study was to determine the correlation between polypharmacy and length of stay in geriatric patients at Moehammad Hoesin Hospital Palembang. Methods. This was a cross-sectional study with a correlation test design conducted at Dr. Mohammad Hoesin Hospital (RSMH) Palembang from …

Depressive Symptoms As A Predictor Factor Of All-Cause Mortality Within Six Months In Elderly Hemodialysis Patients, Langgeng Perdhana, Shofa Chasan, Yudo Murti Mupangati, Siti Nuraini

Jurnal Penyakit Dalam Indonesia

Introduction. Depression is a mental disorder that is often found in the elderly and hemodialysis patients, resulting in bad effects on patients. There is no study on the relationship between depression and all-cause mortality risk in elderly hemodialysis patients in Indonesia. This study aimed to determine the role of depression as a predictor factor of all-cause mortality within 6 months in elderly hemodialysis patients. Methods. A prospective cohort study was conducted from February to August 2020 at the hemodialysis unit of Roemani Muhammadiyah Hospital, Semarang. The inclusion criteria were elderly patients (aged ≥60 years), undergoing hemodialysis ≥3 months, hemodialysis frequency …

Android-Based Waste Education App: An Information Media On Zero-Waste Programs, Muhammad Zamroni Uska, Rasyid Hardi Wirasasmita, Baiq Desi Dwi Arianti, Yosi Nur Kholisho, Muhammad Djamaluddin, Jamaluddin Jamaluddin

Elinvo (Electronics, Informatics, and Vocational Education)

Zero waste is one of the programs from the government of West Nusa Tenggara Province in Indonesia, where this program aims to provide education about waste to the public so that the waste can be processed or recycled so that it can be useful. Therefore, for the sake of creating a zero waste culture in the community, it is necessary to have media that provide education to the public about this program. The purpose of this article is to discuss the process of developing an Android-based waste education application as a medium of information about zero waste. This study uses …

Pengaruh Protokol Hidrasi Dan Status Hidrasi Terhadap Kekuatan Otot Tungkai Bawah, Atensi, Dan Passing Atlet Futsal Remaja, Leonardo Lubis, Nadhifah Salsabila, Siska Wiramihardja

Jurnal Keolahragaan

Tujuan penelitian ini untuk mengetahui pengaruh protokol hidrasi dan status hidrasi terhadap performa kekuatan otot tungkai bawah, atensi, dan passing atlet futsal. Metode yang digunakan adalah analitik kuantitatif dengan desain pretes (sebelum penerapan protokol hidrasi) dan postes (setelah 3 minggu penerapan protokol hidrasi) 22 atlet futsal Akademi Mayasari Bandung. Protokol hidrasi yang diberikan yaitu subjek mengonsumsi 500 mL air 1-2 jam sebelum latihan, 250-500 mL air 15 menit sebelum latihan, dan 500 mL-2 L air selama 1 jam latihan dengan interval minum setiap 20 menit. Pengukuran berat badan sebelum dan sesudah latihan, dilakukan menggunakan Tanita Body Composition Scales untuk menentukan …

Perceptual Motor Test For Children 5-6 Years Old, Yudanto Yudanto, Abdul Mahfudin Alim, Ahmad Nasrulloh

Jurnal Keolahragaan

This research and development aims to produce perceptual motor tests for children aged 5-6 years. The development procedure adapted the Borg and Gall model, namely: (1) the preliminary study and planning stage, (2) the product development stage, (3) the expert validation stage, 4) the trial phase, and (5) product revision. The trial subjects used 10 children aged 5-6 years. The data used in this research are quantitative and qualitative data. Quantitative data were obtained from the results of the validation of the perceptual motor test draft and trials. Qualitative data obtained from the results of a questionnaire in the form …

Swimming Training On Moderate Intensity Significantly Reduces Total Cholesterol And Bodyweight On Hypercholesterolemic Rat Model, Anindya Mar'atus Sholikhah, Mochamad Ridwan

Jurnal Keolahragaan

It is well established that regular exercise has many positive benefits on health. Exercise at the appropriate intensity and level has been shown to improve lipid profile and reduce the risk of cardiovascular disease. This study investigates the effect of swimming training on total cholesterol levels and body weight in male Wistar rats. Thirty rats weighing 150-200 grams were randomly divided into one control (C) and two treatment groups (ST=swimming training, SED=sedentary activity). Rats in control (C) group were fed a standard diet, while rats in both treatment groups were fed high-fat diet-induced hypercholesterolemia for three weeks. Rats in ST …

The Use Of Participatory Action Research To Improve Energy Intake Of The Soccer Athletes, Irwan Budiono, Arif Setiawan, Arif Rahmat Kurnia

Jurnal Keolahragaan

It was estimated that 5, 3 % of Universitas Negeri Semarang (UNNES) soccer athletes were malnourished. The consumption survey results show that the average dietary energy intake (DEI) was 63.24% of the dietary reference intake (DRI). The purpose of this study was to improve the energy intake of athletes. This research was using a participatory action research method. The study was divided into 2 cycles which allocated in 30 days. This research was using a total sampling method. A total of 19 UNNES soccer athletes were involved as research subjects. Data on nutritional status and energy intake were analyzed to …

The Effect Of Shadow Training Using Consecutive Steps And Cross Steps On The Agility Of The Footwork Of Badminton Athletes, Ahiriah Muthiarani, Lismadiana Lismadiana, Rina Yuniana

Jurnal Keolahragaan

This study aims to determine the effect of sequential and crossed step shadow exercises, as well as the differences between the two on improving footwork agility badminton athlete PB Wiratama Jaya Yogyakarta. This research is a quasi-experimental study, with a two group pre-test post-test design. The sample in this study amounted to 22 male athletes. The instrument in this study used a series of foot exercises proposed by Tohar. Data analysis techniques on hypothesis testing using the t test. The results showed: first, there was an effect of sequential step shadow training on the agility of the athlete's footwork PB …

Relationship Between Somatotype And Physical Fitness: Study On Badminton Athletes Of Pb Djarum Kudus, Nurlita Tri Ayuningtyas, Hardhono Susanto, Suroto Suroto

Jurnal Keolahragaan

Badminton athletes should have good physical abilities supported by the suitability of body type (somatotype) as it affects their biomechanics in badminton and performance. The purpose of this study was to explore the correlation between Heath Carter somatotype component factors that affect physical fitness. This study was a cross-sectional research design was used with 43 athletes in PB Djarum Kudus who were selected purposively to be the respondents. The data on Heath Carter somatotype was obtained from anthropometric measurements to generate somatotype scores, namely endomorphy, mesomorphy, and ectomorphy. Cardiorespiratory endurance data were obtained using Balke test, power using vertical jump, …

Program Asuhan Gizi Olahraga (Pago) Atlet Sepatu Roda Sebagai Strategi Memperbaiki Profil Status Gizi, Biokimia Dan Kualitas Asupan, Fillah Fithra Dieny, Firdananda Fikri Jauharany, Ayu Rahadiyanti, Deny Yudi Fitranti, A. Fahmy Arif Tsani, Dewi Marfu㢂¬„¢Ah Kurniawati

Jurnal Keolahragaan

Penelitian bertujuan menganalisis pengaruh pemberian intervensi gizi berupa edukasi dan konseling gizi pada atlet sepatu roda remaja terhadap status gizi, status hidrasi, status biokimia, dan asupan gizi. Penelitian one group pre and post test design yang melibatkan 11 atlet di Klub Sepatu Roda Kairos Semarang. Variabel terikat adalah profil antropometri (berat badan, tinggi badan, fat mass, massa otot, body water), status hidrasi, status biokimia (kadar gula darah puasa, asam urat, kolesterol, hemoglobin), dan asupan makan. Uji Wilcoxon digunakan untuk menganalisis perbedaan profi antropometri, status hidrasi, status biokimia, dan asupan makan subjek antara sebelum dan sesudah intervensi. Terdapat perbedaan yang …

The Differences Response Of Massage Types With Variation Massage Pressure On Running Speed In Popda Sleman Athletics, Riza Galih Mustika Rini, Eddy Purnomo

Jurnal Keolahragaan

This study aims to improve the athlete's performance from the physiological aspect by knowing the differences in the response of sport massage and swedish massage with variations in pressure (light, medium, and heavy) on the hind limbs a 30 m running speed taken four times. This research is a quasi-experimental design, with the research subjects of POPDA Sleman athletic athletes with sample of 20 people. The sample was divided by matching pairs with the aim of both groups getting a balanced power. The treatments used are sports massage with movement manipulation (effleurage, tapotement, shaking/vibration) and swedish massage with movement manipulation …

The Difference Between Male And Female Student's Physical Activity In Urban Region During School Recess, Agus Supriyanto, Erwin Setyo Kriswanto, Yudik Prasetyo, Sigit Dwi Andrianto

Jurnal Keolahragaan

Physical activity is one of the important components to support individual fitness and health. This study aims to determine differences in physical activity between male and female students of class V in urban areas during school breaks. This type of research is comparative descriptive. The research sample consisted of 54 elementary school students of grade V in urban areas in Depok Subdistrict, Sleman Regency, Yogyakarta Special Region. The technique used to determine the research sample is purposive sampling. The instrument in this study was the Nesco FJ 101 pedometer. The data analysis technique used in this study is a percentage. …

The Effect Of Skipping Combination With Body Weight Training On Cardiorespiratory Endurance And Body Mass Index (Bmi) As A Covid-19 Prevention Effort For Overweight Adolescents, Ahmad Nasrulloh, Rina Yuniana, Kukuh Wahyudin Pratama

Jurnal Keolahragaan

This study aims to determine the effect of skipping combination with body weight training on cardiorespiratory endurance and BMI as an effort to prevent Covid 19 for overweight adolescents. This research is an experimental research. In this study, treatment was given in the form of skipping exercise combined with body weight training for 8 weeks with a frequency of 3 times / week, an intensity of 60%-70% MHR with a duration of 30 minutes. The population in this study were teenagers. Sampling was done by purposive sampling on adolescents aged between 17-21 years and overweight. Instrument used to measure VO2 …

The Effect Of Brain Vitalization Exercise On Muscle Strength And Endurance In People With Dementia, Mustika Fitri, Ajeng Fauziyah, Hana Astria Nur

Jurnal Keolahragaan

This study aims to determine the effect of brain vitalization exercise on muscle strength and endurance in people with dementia. The pre-experimental method with a one-group pretest-posttest design was used in this study. Purposive sampling technique was used in this study, then a sample of 31 people with dementia was obtained from a population of 78 people in Cibeunying Kidul District. The Arm Curl Test instrument is used in research that aims to measure arm muscle strength and Chair Stand Test which aims to measure leg muscle endurance. The data analysis technique in this study used Paired Sample T Test …

Aktivitas Olahraga Bulu Tangkis Dan Respon Perubahan Asam Urat Darah Usia Produktif, Angkit Kinasih, Ronaldo Lomi Djara, Ferry Fredy Karwur

Jurnal Keolahragaan

Penelitian ini bertujuan untuk mengetahui ada tidaknya respon perubahan pada kadar asam urat akibat aktivitas olahraga bulu tangkis. Desain penelitian ini adalah quasi eksperimen. Sampel yang digunakan sebanyak delapan responden dengan kriteria tertentu. Perlakukan aktivitas fisik dilakukan dua kali pada hari yang berbeda dengan 4 kali pengukuran kadar asam urat. Metode penelitian yang digunakan adalah repeated measure analysis. Ketika subyek diukur berulang kali dengan jumlah yang sedikit per percobaan maka repeated measures analysis dapat digunakan. Hasil penelitian menunjukkan bahwa perlakukan olahraga bulu tangkis memberikan respon perubahan yang signifikan terhadap perubahan kadar asam urat dengan nilai probabilitas sebesar 0,038. Hasil ini …

Analisis Kebijakan Penempatan Ahli Gizi Sebagai Tenaga Keolahragaan Indonesia, Mirza Hapsari Sakti Titis Penggalih, Laksono Trisnantoro, Zaenal Muttaqqien Sofro, Mutiara Tirta Prabandari Lintang Kusuma, Mustika Cahya Nirmala Dewinta, Ibtidau Niamilah, Meta Anastasia, Edi Nurinda Susila

Jurnal Keolahragaan

Peran ahli gizi sebagai tenaga keolahragaan pada dasarnya merupakan mandat hukum dari Undang-Undang No. 3 Tahun 2005 tentang Sistem Keolahragaan Nasional, khususnya Pasal 63 yang menyebutkan bahwa ahli gizi merupakan salah satu tenaga keolahragaan. Pada praktiknya, implementasi peran ahli gizi sebagai tenaga keolahragaan di pusat pembinaan atlet masih belum optimal. Keterbatasan sumber daya manusia dan anggaran, serta belum adanya kebijakan operasional yang mengatur tentang penempatan ahli gizi di pusat pembinaan atlet menjadi beberapa kendala yang perlu solusi. Pengkajian ini menggunakan pendekatan kualitatif dengan melakukan studi dokumen terhadap delapan peraturan yaitu 1 undang-undang, 1 perpres dan 6 permen. Seluruh dokumen kebijakan …

Iclas Laq Network For The Promotion Of Animal Quality In Research., Patri Vergara, Gregory Ballard, Cynthia Besch-Williford, Nobuhito Hayashimoto, Cynthia Pekow, Ana Perez, Katja Schmidt, William Shek, Martin Toft, Atsushi Yoshiki

Faculty Research 2023

ICLAS Laboratory Animal Quality Network (LAQN) programs currently consist of the Performance Evaluation Program (PEP), which focuses on microbial monitoring by and for laboratory animal diagnostic laboratories, and the Genetic Reference Monitoring Program (GENRef), which provides assay-ready reference DNA for genetic testing of mouse strains. Since 2008, PEP has grown to become a truly international program with participating laboratories in 5 continents. Launched in 2016, GENRef currently distributes DNA from 12 common inbred mouse strains for use in genetic monitoring of locally inbred colonies as well as for genetic testing of stocks, particularly genetically engineered stocks, of uncertain origins. GENRef …