Digital Commons Network^™

Parent–Child Leisure And Parent Affect: The Role Of Family Structure, Camilla Hodge, Jocelyn Wikle

Faculty Publications

This study evaluates differences in parent–child leisure and parent affect across single- and two-parent families. The Ecology of Family Experiences framework suggests contextual factors such as family structure and the novelty of the activity environment contribute to heterogeneity in how parents experience leisure, partly because constraints may differ across family structures. Using a large, nationally representative data sample of parents from the American Time Use Survey (N = 78,353), this study shows single-parents experience leisure deficits compared to other parents, and leisure deficits are greatest in home-based leisure. Additionally, using a subsample (N = 16,214), we found that at-home leisure …

Are Pharmacists Up To Speed?: Pharmacy Driven Initiatives, Allison Vargas

All Publications

No abstract provided.

A Qualitative Study Of Emergency Department Delirium Prevention Initiatives, Anita Chary, Shan W Liu, Ilianna Santangelo, Kyler M Godwin, Christopher R Carpenter, Aanand D Naik, Maura Kennedy

Faculty, Staff and Students Publications

BACKGROUND: Delirium is a serious but preventable syndrome of acute brain failure. It affects 15% of patients presenting to emergency care and up to half of hospitalized patients. The emergency department (ED) often represents the entry point for hospital care for older adults and as such is an important site for delirium prevention.

OBJECTIVE: We sought to characterize delirium prevention initiatives in EDs in the United States and Canada.

METHODS: We conducted qualitative interviews with 16 ED administrators representing 14 EDs with delirium prevention initiatives. We used a combined deductive-inductive approach to code responses about involved staff, target patient population, …

Esophageal Perforation Successfully Treated With Evt, Kavea Panneerselvam, Ronald Samuel, Robert J Sealock

Faculty, Staff and Students Publications

Esophageal perforation is rare and carries high morbidity and mortality. A high degree of suspicion is needed for timely diagnosis and treatment. A 54-year-old man presented with fever and confusion. Imaging revealed air in the hepatic inferior vena cava and concern for a fistula between the distal esophagus and the inferior vena cava. An upper endoscopic evaluation revealed a dental floss pick penetrating the distal esophagus. The foreign body was removed, and endoluminal vacuum therapy was used to close the perforation. Endoluminal vacuum therapy is an emerging therapy to treat full-thickness gastrointestinal injuries.

Severe Inflammatory Colitis Related To Encorafenib And Binimetinib Following Immune Checkpoint Inhibitor Therapy, Aaron G Issac, David Szafron, Dongguang Wei, Jennifer L Mcquade, Yinghong Wang

Faculty, Staff and Students Publications

Encorafenib, a BRAF kinase inhibitor, in combination with binimetinib, a selective MEK inhibitor have known gastrointestinal adverse events; however, adverse colitis events have not been well studied. We report a case series of 4 patients with melanoma who developed inflammatory colitis after BRAF and MEK inhibition with encorafenib and binimetinib, respectively. In the setting of immune checkpoint inhibitor use, BRAF and MEK inhibitors can cause significant inflammatory colitis with endoscopic patterns of predominant right colon ulcerations. It can lead to significant morbidity and frequent interruption of cancer treatment. Early recognition and prompt intervention are critical to improving patient outcomes.

Cytomegalovirus Infection Among Patients With Cancer Receiving Immune Checkpoint Inhibitors, Kavea Panneerselvam, David Szafron, Rajan N Amin, Dongguang Wei, Dongfeng Tan, Mehmet Altan, Pablo C Okhuysen, Malek Shatila, Gottumukkala Subba Raju, Anusha S Thomas, Yinghong Wang

Faculty, Staff and Students Publications

BACKGROUND: Immune checkpoint inhibitors (ICIs), used for the treatment of solid and hematologic malignancies, come with the risk of immune-related adverse events (irAEs). Opportunistic infections (e.g., cytomegalovirus [CMV]) mimic irAE symptoms and are understudied in this population. We aimed to describe the incidence, characteristics, treatment and outcomes of CMV infection in ICI-treated patients.

METHODS: We conducted a single-center retrospective review of all adult patients who were CMV-positive after ICI therapy between 06/2011 and 05/2020. A CMV-positive non-ICI cohort was matched to the ICI group based on age, sex and cancer type. Variables of interest were collected through electronic medical records. …

Inpatient Coding System And Opportunities For Documentation Optimization: An Interactive Session For Internal Medicine Residents, Lindsey Jordan Gay, Doris Lin, Ziba Colah, Glynda Raynaldo

Faculty, Staff and Students Publications

INTRODUCTION: The Inpatient Prospective Payment System, the framework for categorization of admissions, is based upon physician documentation leading to International Classification of Diseases, Tenth Revision code generation and Medical Severity Diagnosis-Related Group (MS-DRG) assignment. In this curriculum, we introduced internal medicine residents to this inpatient coding framework and its effects on hospital quality metrics and reimbursement. We focused on educating learners about the importance of physicians being proficient in providing thorough and specific clinical documentation to produce appropriate DRG assignment.

METHODS: Internal medicine residents participated in a 90-minute session that introduced the basic framework of inpatient coding, discussed effects of …

Minimum Dataset And Metadata Guidelines For Soil-Test Correlation And Calibration Research, Nathan A. Slaton, Sarah E. Lyons, Deanna L. Osmond, Sylvie M. Brouder, Steve W. Culman, Gerson L. Drescher, Luciano C. Gatiboni, John Hoben, Peter J.A. Kleinman, Joshua M. Mcgrath, Robert O. Miller, Austin Pearce, Amy L. Shober, John T. Spargo, Jeff J. Volenec

Crop, Soil and Environmental Sciences Faculty Publications and Presentations

Soil-test correlation and calibration data are essential to modern agriculture, and their continued relevance is underscored by the expansion of precision farming and the persistence of sustainable soil management priorities. In support of transparent, science-based fertilizer recommendations, we seek to establish a core set of required and recommended information for soil-test P and K correlation and calibration studies, a minimum dataset, building on previous research. The Fertilizer Recommendation Support Tool (FRST) project team and collaborators are developing a national database that will support a soil-test-based nutrient management decision aid tool. The FRST team includes over 80 scientists from 37 land-grant …

Physical Activity And Diet Quality In Relation To Non-Alcoholic Fatty Liver Disease: A Cross-Sectional Study In A Representative Sample Of Us Adults Using Nhanes 2017–2018, Natalia I Heredia, Xiaotao Zhang, Maya Balakrishnan, Carrie R Daniel, Jessica P Hwang, Lorna H Mcneill, Aaron P Thrift

Faculty, Staff and Students Publications

The association of physical activity (PA) and diet quality with non-alcoholic fatty liver disease (NAFLD) and NAFLD-related fibrosis have never been examined in a representative sample of U.S. adults using a more precise form of measuring NAFLD. The purpose of this study was to assess the associations of PA and diet quality (Healthy Eating Index [HEI]-2015) with NAFLD and a subset with advanced fibrosis (F3-4) as assessed by vibration-controlled transient elastography with controlled attenuation parameter in a representative sample of U.S. adults. This cross-sectional analysis uses data from 2017-2018 National Health and Nutrition Examination Survey. NAFLD was defined as controlled …

Racial/Ethnic Variations In Alcohol And Cigarette Use By Pregnancy Status Among 20- To 44-Year-Old Women, Nhanes 2001–2018, Jacqueline M Hirth, Catherine Valadez, Sandra Gonzalez, Alicia Kowalchuk, Judith A Gutierrez, Roger Zoorob

Faculty, Staff and Students Publications

OBJECTIVES: This study examines alcohol consumption and smoking behaviors by pregnancy status and race/ethnicity in order to inform improved interventions designed to assist women of all races to avoid alcohol and tobacco use during pregnancy for their health and to prevent potential fetal exposure.

METHODS: This retrospective secondary data analysis utilized nationally representative National Health and Nutrition Examination Survey data between 2001 and 2018. Smoking and alcohol use were evaluated by race/ethnicity and pregnancy risk. Sexual behavior, reproductive health, and prescription drug use determined pregnancy risk, categorized as low pregnancy risk, at risk of becoming pregnant, and pregnant. Binary and …

A Survey On Self-Medication For The Prevention Or Treatment Of Covid-19 And Distrust In Healthcare Of Veterans In A Primary Care Setting In The United States, Eva Amenta, Larissa Grigoryan, Laura Dillon, Casey Hines-Munson, John Van, Barbara Trautner

Faculty, Staff and Students Publications

BACKGROUND: The SARS-CoV-2 (COVID-19) pandemic brought the public overwhelming and conflicting information. Rates of trust in healthcare professionals have been declining among laypersons over the past five decades. In this setting, we sought to evaluate the use of medications, both with or without a prescription, to prevent and treat SARS-CoV-2 as well as trust in healthcare among patients in a primary care clinic.

DESIGN: We surveyed 150 veterans in primary care clinic waiting rooms at a large southwestern tertiary care Veterans Affairs hospital. This survey was performed in March-November 2021.

METHODS: The survey asked about respondents' demographics, use of medications, …

The Effect Of Er:Yag, Nd:Yag And Co2 Laser Combined With Hydrogen Peroxide, Sodium Hypochlorite, Chlorohexidine Or Fluoride On Reducing Oral Bacterial Count Implicated In Root Caries, Nitya Reddy

Theses and Dissertations

Purpose: Lasers have been used for treatment of dentinal hypersensitivity and for various bacterial reduction indications in periodontology. Their effectiveness in killing oral bacteria is not well known. The compounding effect of the combination of a laser treatment and adjunct antimicrobial agent use on bacterial viability is still evolving. The purpose of this in vitro study was to evaluate the effect of three lasers commonly used in dentistry in conjunction with chlorhexidine (CHX), hydrogen peroxide (H₂O₂), sodium hypochlorite (NaOCl), or sodium fluoride (NaF) on viability of oral bacteria associated with root caries.

Methods: Three …

Outcome Of Vital Pulp Therapy On Immature Permanent Teeth With Calcium Silicate-Based Materials: Retrospective Cohort Study, Brian I. Hone

Theses and Dissertations

Introduction: The purpose of vital pulp therapy is to maintain pulp viability by eliminating bacteria from the dentin-pulp complex and to establish an environment in which apexogenesis can occur. The aim of this retrospective cohort study was to evaluate the clinical and radiographic outcomes of vital pulp therapy on immature permanent teeth using different calcium silicate-based materials. Methods: This study was carried out in the Virginia Commonwealth University Graduate Endodontics department in Richmond, Virginia. Vital pulp therapy cases performed by graduate endodontic residents were retrospectively searched and charts were reviewed to determine inclusion into this study. All cases …

A Novel Approach To Reducing Adiposity Among Young Men, Jean M. Reading

Theses and Dissertations

Background

Lifestyle intervention is the first line treatment for obesity. Yet, young men are underrepresented in lifestyle interventions, which is posited to be the result of unmet needs and overall low concern for weight management. The aims of this dissertation are to:

Papers 1 and 2: Test the preliminary efficacy, feasibility, and acceptability of a self-guided lifestyle intervention for young men.

Paper 3: Explore the behavioral and physiological factors associated with changes in adiposity among young men and women enrolled in a more intensive lifestyle intervention.

Results

Papers 1 and 2: The self-guided intervention produced modest weight …

Processes Underlying Black American College Students’ Mental Health: Examining The Roles Of Mental Health Literacy, Ethnic-Racial Identity, And Mental Health-Related Behaviors, Chloe Walker

Theses and Dissertations

Addressing the mental health of college students is a persistent and increasing priority (Auerbach et al., 2018), especially among Black American individuals. Given prevalent mental health disparities, it is critical to understand the association between Black American emerging adults’ mental health literacy (MHL) and mental health outcomes including promotive mental health-related behaviors (MHRBs) and symptoms (i.e., anxiety and depressive symptoms), and the modifiable underlying factors that inform them. Guided by the Theory of Planned Behavior (Ajzen, 1991) and the Identity-based Motivation theory (Oyserman & Yoder, 2007), the present study aimed to examine the relation between mental health literacy and mental …

The Role Of Human Dopamine Transporter Threonine 261 And Serine 262 In Amphetamine Regulation Of Transporter Function And Surface Expression, Sina Abdollahi

Theses and Dissertations

Amphetamine (AMPH) has been used clinically and recreationally around the world for years. A 2021 study reports a 67.5% rise in AMPH use from 2010-2017 across all fifty states. Study also shows that 30% of patients with AMPH-induced psychosis end up with primary psychosis over time. AMPH works by inhibiting monoamine (Norepinephrine (NE), Serotonin (5-HT), and Dopamine (DA) reuptake followed by triggering transporter mediated monoamine release and consequently increases monoamine concentrations in extracellular synaptic space. AMPH also works as a substrate for monoamine transporters, enters the neuron, and once its inside the neuron, it will prevent the storage of monoamines …

Removal Of Prefabricated Zirconia Crowns From Primary Anterior Teeth With Er,Cr:Ysgg Laser Compared To A High-Speed Handpiece: An In- Vitro Study, Andrew Crowell

Theses and Dissertations

Purpose: The aim of this study was to compare the time and pulpal temperature changes associated with the removal of prefabricated zirconia crowns from primary anterior teeth using an Er,Cr:YSGG laser compared to a rotary hand-piece.

Methods: This in-vitro study was conducted using extracted primary incisors. Teeth were prepared and restored with prefabricated zirconia crowns (NuSmile^®, Houston, TX, USA) sizes 4 and 5 cemented with resin-modified glass-ionomer cement. Restored teeth were stored in a humidor for at least 48 hours prior to removing crowns from the teeth using either an air-rotary hand-piece (HG, N=17) or erbium, chromium: …

Empowerment In Adolescents And Young Adults With Cystic Fibrosis, Rachel Holder

Theses and Dissertations

Adolescence and young adulthood is a pivotal time for individuals with cystic fibrosis (CF) that is characterized by increased self-management, transition to adult-oriented healthcare, and often a decline in treatment adherence and health-related quality of life (HRQoL) (Abbott et al., 2015; Modi et al., 2008). The literature regarding which factors are important for readiness to transition, treatment adherence, and HRQoL is limited in this population. However, empowerment has emerged as a salient construct in other disease groups (Acuña Mora et al., 2019; Burström et al., 2019; Kaal et al., 2017). As such, this thesis determined the convergent validity of the …

Flourish: Exploring Healing Environments In A Residential Treatment Setting, Emily D. Kalafian

Theses and Dissertations

The following project explores the ways in which our environments promote healing and support recovery through the design of a residential center for eating disorder recovery. The center will serve 8-10 young women as they seek recovery from restrictive forms of eating disorders. The center will accommodate the necessary staff personnel as well as spaces for supporting activities and wraparound services. The project intends to create a place for healing that feels safe, warm, and considers patients’ needs for autonomy, dignity, and a sense of control amidst disorder. This is a place to create meaningful relationships and to participate in …

It Takes A Muscle: Wholes, Holes, And Other Voids, Saar Shemesh

Theses and Dissertations

IT TAKES A MUSCLE¹

In the BELLY of the BEAST, the HUMAN

in the deep end of a SWIMMING POOL

in a GRAVE, looking up/out from within

at the base of a CRATER, ABYSS, PIT

the room as a CRADLE, INCUBATOR

architecture as MOTHER MOULD.²

____________________________

¹ Title is borrowed and abbreviated: Spectral Display, “It Takes A Muscle To Fall In Love,” 1982.

² For what American-English delineates as ‘mold,’ British-English uses ‘mould’ and is more specific in its technicality. The former doesn’t distinguish in spelling between mold (fungus) and mold (mould). I’m not particularly a fan of …

Supported Employment Services And Employment Outcomes For Low-Income Youth With Intellectual And Developmental Disabilities: A Case Control Study, Hannah Seward Phd

Theses and Dissertations

Transition-age youth, ages 14-24 years old, with intellectual and developmental disabilities (IDD) face unique barriers to entering the labor force when exiting high school. These barriers can be even more severe if the youth is from a low-income background. Supported employment (SE) services may help this population overcome these barriers and be employed in competitive integrated employment (CIE) settings. SE provides an employment specialist to guide them through obtaining and retaining a job (McDonough & Whittenburg, 2020; Wehman et al., 2007). However, limited research has been done on the SE experiences and outcomes of transition-age youth with IDD (Wehman et …

Alcohol And Other Addictive Behaviors Among Bariatric Surgery Patients, Rachel M. Arnold

Theses and Dissertations

Research has repeatedly highlighted a high rate of comorbidity of addictive behaviors in both clinical and non-clinical samples. While polydrug use has received significant attention in recent years, less is known about rates of comorbidity with behavioral addictions such as eating, work, exercise, or sex. Individuals with a history of bariatric surgery may provide a unique opportunity to examine the potential co-occurrence of addictive behaviors. High rates of food addiction symptoms and changes in alcohol use patterns post-surgically have highlighted a potential gap in our understanding of bariatric patients and their needs post-surgically. Using a composite measure of addictive behaviors, …

Leading Through Crisis: The Covid-19 Pandemic’S Impact On The School Principalship, A Delphi Study, Matthew J. Togna

Theses and Dissertations

This dissertation study examined the impacts of the COVID-19 Pandemic on the K-12 School Principalship and attempted to forecast the future of the principalship post-Pandemic. Using a forecasting method known as the Delphi Technique, I solicited public K-12 principals working in the Commonwealth of Virginia with at least 3 years of administrative experience to serve as participants. In total, 26 practicing principals completed three questionnaires offering their expert opinions on pre-Pandemic roles and responsibilities of the school principal and how those roles were impacted throughout the Pandemic. Additionally, the participants made predictions about the future of the school principalship. Findings …

Modification Of Culture Medium And Identification Of Microbial Contaminants For Improved In Vitro Propagation Of Freshwater Mussels, Raquel M. Wetzell

Theses and Dissertations

In vitro propagation efforts play an essential role in conserving and restoring threatened freshwater mussel populations by circumventing the need for a fish host. Across a broad range of taxa, transformation is induced with an artificial M199 medium and rabbit serum. However, such formulation may not be sufficient in culturing critical species with more specific physiological requirements. In this study, multiple serum mixtures were tested to improve in vitro transformation of two freshwater mussel species: yellow lampmussel (Lampsilis cariosa) and tidewater mucket (Atlantaconcha ochracea). These species were selected because they parasitize similar fish host species but …

Caregiver's Nicu Experiences And Its Impact On Services, Crystal L. Hence

Theses and Dissertations

Having a child spend time in the Neonatal Intensive Care Unit is documented as a stressful experience for caregivers. Previous literature documents caregivers’ difficulties navigating the Neonatal Intensive Care Unit, showing that this problem has persisted for close to 20 years. Early Intervention can provide benefits to infants born prematurely, who may be more at risk for developmental delays and since the goal of Early Intervention is to provide services that help families in their daily lives, it has benefits for caregivers as well. Yet, Early Intervention enrollment remains low across the state of Virginia. This study using a qualitative …

Tummy Time In Infancy: Real-World Assessments And Associations With Developmental Outcomes In Early Childhood, Ketaki Inamdar

Theses and Dissertations

Tummy time or awake, supervised, prone play is an important developmental play position in infancy. Engaging in more than 15 minutes of tummy time per day is associated with a lower risk of plagiocephaly, lower body mass index, and achievement of higher motor scores in full-term and at-risk preterm infants. However, there are significant gaps in the measurement of tummy time in current literature. Conventionally used subjective parent reports have not been validated against gold standard direct observation, and the feasibility and real-world validity of objective solutions such as wearable sensors has not been examined in full-term and at-risk preterm …

Complementary Feeding Types, Timing And Practices By Mothers In Al-Kut City, Samaa Abdulkareem, Waleed Al-Ani

Iraqi Postgraduate Medical Journal

BACKGROUND: Complementary feeding is a process starting when breast/formula milk alone is no longer sufficient to meet the nutritional requirements of infants, and therefore other foods and liquids are needed, along with breast/formula milk. AIM OF THE STUDY: To determine the type and time of initial complementary feeding practiced by mothers in Kut City and its relation with some associated factors. METHODS: A descriptive primary health center-based study conducted on 500 mothers attending 29 primary health care centers in Al-Kut City for the period of 4 months extended between 1st of April to 31st of July 2017. Data were collected …

Splanchnic Oxygenation And Feeding Intolerance In The Very Low Birthweight Infant, Melissa C. Dollings

Theses and Dissertations

SPLANCHNIC OXYGENATION AND FEEDING INTOLERANCE IN THE VERY LOW BIRTHWEIGHT INFANT

By Melissa C. Dollings, Ph.D.

A dissertation submitted in partial fulfillment of the requirements for the degree of Doctor of Philosophy at Virginia Commonwealth University

Virginia Commonwealth University, 2022

Major Director: Lisa F. Brown, Ph.D., RN, School of Nursing

Background. Feeding intolerance is common in preterm infants but can be an ominous precursor of necrotizing enterocolitis, a life-threatening gastrointestinal disease. The definition and management of feeding intolerance vary widely. This research examined the relationship

between feeding intolerance, intrauterine factors, extrauterine factors, and intestinal immaturity and circulatory immaturity in the …

Local Context And Post-Crisis Social Venture Creation, Sergey Anokhin, Todd Morgan, Lisa Jones Christensen, William Schulze

Faculty Publications

Research summary: We investigate the effects of local market and government failure on the creation of social ventures in the context of post-crisis recovery during the period following the dot-com crisis and ending before the housing bubble burst across all Ohio counties. Drawing on social embeddedness theory, we posit that social venture creation rates vary across local contexts and are higher in communities characterized by market and government failures. Longitudinal contextual data from 88 Ohio counties indicates that situations characterized by failures of both types are especially conducive to the creation of local social enterprises. We address the shortage of …

Western Region Health & Wellness Programming Efforts: Qualitative Results From A Three-Part Listening Session, Cris L. Meier, Lily Ward, Anders Van Sandt, Sue Schneider, Riana Gayle

All Current Publications

The purpose of this project was to understand the programming efforts and experiences of Extension professionals in the Western Region of the United States. The Health and Wellness Working Group team held a series of listening sessions with a closed cohort of Extension professionals, hoping to learn from each other while also building the foundation for future collaborations and conversations about health and wellness programing in the western region.

The objectives were to understand: (1) the state of health and wellness work in the western region, including the gaps and challenges, (2) the programs that currently exist and ways that …