Digital Commons Network^™

The Use Of Exogenous Acrp30 As A Promising Amelioratory Compound Regarding Insulin Resistance And Type Ii Diabetes Mellitus, Stephen L. Romero

Honors Undergraduate Theses

As numerous bodies of research have characterized the adipocytokine adiponectin (ACRP30) as an anti-diabetic compound, this work serves as an analysis to partly elucidate the potential usage of supplementary adiponectin as a therapeutic compound in the treatment of type II diabetes mellitus. In this work, a meta-analysis was conducted to centralize large amounts of data on adiponectin’s insulin sensitizing characteristics in conjunction with like-minded studies utilizing metformin treatment as the diabetic standard of care. Upon comparison of fasting glucose, fasting insulin, and glucose tolerance test area under the curve reduction percentages, it is quite clear that ACRP30 has significant insulin …

The Relationship Between Sarcopenia And Diabetes Among Different Ethnic Groups, Rachel K. Williams

Honors Undergraduate Theses

Sarcopenia and diabetes are two conditions that reflect ongoing changes in global health trends: aging and obesity. Sarcopenia affects approximately 10-40% of the global population and type II diabetes affects around 415 million individuals (6.28% globally), with obesity contributing to a majority of the cases. Currently, approximately 9.3% of the population (727 million individuals) is aged 65 years or older; this number is predicted to reach 16% of the global population (around 1.5 billion individuals) in 2050. Many developed countries are undergoing demographic population pyramid rearrangements whereby an increasingly aging population must be supported by a shrinking youth cohort. Sarcopenia …

The Cost, Politics And Controversy Of Human Space Flight In Nigeria Or How To Put The First African Astronaut Into Space, Desiree Winns

Honors Undergraduate Theses

The most pressing barriers between reality and the dream of the first African astronaut in space are a lack of resources, cooperation, and support. However, Nigeria presently suffers from the threat of famine, intercommunal violence, and population displacement as a result of terrorism and food insecurity. The reliance upon humanitarian aid from countries such as the United States and international NGOs creates a question of whether Nigeria should even be considering exploration of space. It can be said that any investment into space should instead be granted to displaced people, water and food security, and cracking down on terrorism. Why …

Sexual And Intimate Partner Violence Among The Lgbtq+ College Population, Courteney Lewis

Honors Undergraduate Theses

College-aged students have the highest sexual assault and intimate partner violence victimization rates. Previous studies have linked victimization with poor mental health scores, especially in the LGBTQ+ college population. They also showed a higher rate of victimization for LGBTQ+ students. The goal of this study was to investigate the relationship between victimization and mental health in the LGBTQ+ college population. To conduct this study, I used data from the Spring 2021 and 2022, American College Health Association (ACHA) - National College Health Assessment (NCHA). The results of the study established statistical significance in the rates of sexual violence in LGBTQ+ …

Differences In Nutrition And Eating Patterns Between Youth With Autism Spectrum Disorder And Neurotypical Youth, Mariam Spieler Tahech

Honors Undergraduate Theses

Background: Autism Spectrum Disorder (ASD) is a developmental disorder characterized by difficulties with communication, problems with social interactions, and repetitive patterns. A greater proportion of children with ASD tend to experience nutritional difficulties and feeding issues compared to neurotypical (NT) children; however, limited research has been examined that compares nutritional behaviors between children with ASD and NT youth. Purpose: The purpose of this study was to examine the differences in gastrointestinal issues, weight concerns, and mealtime behaviors in youth with ASD and NT youth. Data was utilized from the 2019 National Survey of Children’s Health which consisted of items related …

The Relationship Between Inflammatory Diet Score And Cancer Outcomes: Systematic Review And Meta-Analysis, Eric Han

Honors Undergraduate Theses

Cancer remains one of the most prevalent diseases in the United States and a leading cause of death. Large prospective studies have found significant correlations between dietary intake and cancer. Chronic inflammation promotes pro-cancer inflammatory environments promoting the formation and growth of tumors while preventing effective anti-tumor responses. Nutrition can impact inflammation, with the intake of certain food items increasing biomarkers for systemic inflammation thus, the objective of this research was to explore the relationship between inflammatory diet score measured by the Dietary Inflammatory index and all-cause mortality, cancer-specific mortality, and cancer recurrence among cancer survivors. Web of Science, Medline, …

An Examination Of Lung Cancer Treatment Characteristics On Lung Cancer Patients With Co-Existing Heart Disease, Elias Rhanime

Honors Undergraduate Theses

With the rising rates of heart disease incidents in the United States and the increase in lung cancer deaths as well, many individuals suffer and get their treatments compromised due to these diseases. Especially considering that many lung cancer and heart disease patients are over 70 years of age, treatment options and success rates drop significantly. Due to this, a great concern is raised for patients with co-existing heart disease and lung cancer. This was a case-control study that assessed lung cancer treatment options and success rates for patients with co-existing heart disease. We used research papers that discussed lung …

Effects Of Post-Exercise Recovery Drink Composition On Subsequent Performance In Masters Class Athletes, Erica Goldstein

Electronic Theses and Dissertations, 2020-2023

Carbohydrate (CHO) and carbohydrate-protein coingestion (CHO-P) have been shown to be equally effective for enhancing glycogen resynthesis and subsequent same-day performance when CHO intake is suboptimal (≤0.8 g/kg). Few studies have specifically examined the effect of isocaloric CHO vs CHO-P consumption on subsequent high-intensity aerobic performance with limited time to recover (≤2 hours) in masters class endurance athletes. Participants (n = 22) were assigned to consume one of three beverages during a 2-hour recovery period: PLA (electrolytes and water), CHO (1.2 g/kg bm), or CHO-P (0.8 g/kg bm CHO + 0.4 g/kg bm PRO). All beverages were standardized to one …

Essential Factors For A Healthy Microbiome: A Scoping Review, Patricia Grace-Farfaglia, Heather Frazier, Maura D. Iversen

Health Science Faculty Publications

Recent discoveries of the purpose and potential of microbial interactions with humans have broad implications for our understanding of metabolism, immunity, the host–microbe genetic interactions. Bioavailability and bioaccessibility of phytonutrients in foods not only enrich microbial diversity in the lower human gastrointestinal tract (GIT) but also direct the functioning of the metagenome of the microbiota. Thus, healthy choices must include foods that contain nutrients that satisfy both the needs of humans and their microbes. Physical activity interventions at a moderate level of intensity have shown positive effects on metabolism and the microbiome, while intense training (>70% VO₂max) …

Patient Referral Failures, Jessica L. Mantel, Leah R. Fowler

Health Matrix: The Journal of Law-Medicine

No abstract provided.

The Impact Of Personalized Nursing Care On Anxiety, Depression, Angina Related Life Quality, And Physiological Conditions In Older Adults With Coronary Heart Disease, Qiao Fan

Public Health Theses

AbstractObjective: To study the impact of medical-personalized nursing care on anxiety, depression, BMI, blood pressure, blood lipid and quality of life in elderly patients with coronary heart disease. Methods: In this study, 160 older adults with coronary heart disease had been enrolled and randomized using the random range method. The control group included 80 older adults who received a conventional nursing intervention, and the experiment group included 80 older adults who were treated with a focused and personalized nursing intervention. The two groups of older adults had been compared and evaluated for Self-rating Anxiety Scale (SAS) mark, the Self-rating Depression …

A Scoping Review Comparing Sustainable Diet Indices, Natalie Henning

Public Health Theses

Interest in environmentally sustainable diets (i.e., diets beneficial for both human and planetary health) has increased as the role of food systems in climate change and population health has become better understood. Sustainable diet indices have been proposed as a holistic approach to assessing diets around the world with regards to human and planetary outcomes. The aim of this scoping review was to summarize and compare sustainable diet indices and their applicability to various populations.A literature search of three databases (Scopus, PubMed, and the Climate Change and Human Health Literature Search Portal) was conducted to identify articles that developed, validated, …

Interactions Between Diabetes And Covid-19: A Scoping Review, Vani Topkar

Public Health Theses

Abstract

Background: The COVID-19 pandemic that started in March 2020 caused by the SARS-CoV-2 virus introduced an incredible number of unknowns that ongoing research aims to investigate. One such unknown is the relationship between diabetes and COVID-19. Existing literature has identified diabetes as a risk factor for poor health outcomes in COVID-19 patients, however, other information is limited and inconclusive.

Objective: There are two primary goals of this scoping review. First, to consolidate existing literature about both associations between COVID-19 and diabetes, and the biological mechanisms of how diabetes and COVID-19 may interact. This includes consolidating information about diabetes as …

The Joint Effects Of Pre-Pregnancy Bmi, Race/Ethnicity On Infants’ Birth Weights, Mei Wang

Public Health Theses

AbstractObjective: We characterized the joint impacts of maternal race/ethnicity and pre-pregnancy BMI on adverse birth weight outcomes including low birth weight (LBW), and macrosomia. Methods: Retrospective cohort study of linked birth data for the years 2016-2020. Maternal race/ethnicity and maternal BMI were the key exposures; we analyzed their joint impact on outcomes using Poisson regression models. Results: When using race-specific reference groups, the difference in risk between NHB and NHW decreased as pre-pregnancy BMI increased and additionally, the difference in risk of macrosomia between the two groups increased with increasing BMI. NHB women generally had higher risk of low birth …

Estimating Groundnut Yield In Smallholder Agriculture Systems Using Planetscope Data, Daniel Kpienbaareh, Kamaldeen Mohammed, Isaac Luginaah, Jinfei Wang, Rachel Bezner Kerr, Esther Lupafya, Laifolo Dakishoni

Faculty Publications - Geography, Geology, and the Environment

Crop yield is related to household food security and community resilience, especially in smallholder agricultural systems. As such, it is crucial to accurately estimate within-season yield in order to provide critical information for farm management and decision making. Therefore, the primary objective of this paper is to assess the most appropriate method, indices, and growth stage for predicting the groundnut yield in smallholder agricultural systems in northern Malawi. We have estimated the yield of groundnut in two smallholder farms using the observed yield and vegetation indices (VIs), which were derived from multitemporal PlanetScope satellite data. Simple linear, multiple linear (MLR), …

Diabetic Self-Management Education Program Evaluation, Amanda Thomas

Doctor of Nursing Practice Projects

Diabetes is a metabolic disease characterized by hyperglycemia, caused by impaired insulin secretions resulting in high hemoglobin A1C levels. Education is beneficial in reducing these as an additive to lifestyle and drug therapy. This student project reflects a program evaluation for a patient diabetes self-management education (DSME) intervention in one small rural outpatient system. DSME classes address the comprehensive blend of clinical, educational, psychosocial, and behavioral aspects of care needed for the daily management of people living with type II diabetes. Three months after completing a DSME the person experiencing type II diabetes has a repeat Hemoglobin A1C level taken …

Ntr 1190 : Food Science, Honors, Nutrition & Dietetics

Approved Course Proposals

No abstract provided.

Evaluation Of Cardiovascular Changes In Patients With Gastric Wall Fat Halo Sign, Ali̇ Küpeli̇, Eser Bulut, Edhem Ünver, Gürkan Danişan

Turkish Journal of Medical Sciences

Background/aim: This study aims to investigate the relationship between gastric wall fat halo sign and potentially associated cardiovascular disease (CVD) in thoracic computed tomography (CT). Materials and methods: Between October 2020 and January 2021, 62 patients with gastric wall fat halo sign and 62 controls were evaluated with thorax CT. Patient's height, weight, body mass index (BMI), sex, age, comorbidities, laboratory parameters, diameters of cardiac axes, aorta and pulmonary artery; aorta and coronary artery calcium scores were recorded for the two groups. Results: No significant differences were found in sex, age, height, body weight or BMI between the two groups …

A Combination Of Q-Tof Lc/Ms And Lc-Ms/Ms Based Metabolomics In Pediatric-Onset Multiple Sclerosis Demonstrates Potential Biomarkers For Unclassified Patients, İsmai̇l Solmaz, Ozan Kaplan, Mustafa Çelebi̇er, İnci̇lay Lay, Fatma Banu Anlar

Turkish Journal of Medical Sciences

Background/aim: Metabolomics has the potential to provide putative biomarkers and insights into the pathophysiology and diagnosis of pediatric multiple sclerosis (pMS), which is an inflammatory demyelinating disorder of the central nervous system with a broad spectrum of clinical manifestations. In this study, we aimed to investigate serum metabolomics in pMS to help elucidate the pathophysiology of MS. Materials and methods: An untargeted approach was applied using the quadrupole time-of-flight liquid chromatography/mass spectrometry (Q-TOF LC/MS) method to study plasma metabolites in patients with pMS (n = 33), patients with unclassified central nervous system demyelinating diseases (n = 6), and age-matched healthy …

Future Pandemics: How Can We Be Ready?, Zeynep Türe Yüce, Emi̇ne Alp Meşe

Turkish Journal of Medical Sciences

No abstract provided.

Frequency Of Alpha-1 Antitrypsin Deficiency And Unexpected Results In Copd Patients In Turkey; Rare Variants Are Common, Mustafa Çörtük, Bariş Demi̇rkol, Meli̇h Akay Arslan, Umut İlhan, Yunus Emre Kalkan, Demet Turan, Şule Gül, Hali̇t Çinarka, Kürşad Nuri̇ Baydi̇li̇, Erdoğan Çeti̇nkaya

Turkish Journal of Medical Sciences

Background/aim: Alpha-1 antitrypsin (?1-AT) is a protease inhibitor that is largely released from liver cells. It inhibits neutrophil elastase and its deficiency increases the risk of developing chronic obstructive pulmonary disease (COPD). The frequency of ?1-AT deficiency has been reported with different prevalence rates in different parts of the world. The most common ?1-AT variant causing ?1-AT deficiency is the Pi*Z allele. In this study, we aimed to determine the frequency of the ?1-AT genotypic variant in COPD patients in our country. Materials and methods: In this study, 196 consecutive COPD patients admitted to our clinic were included. In addition …

Low Handgrip Strength Is Associated With Diabetic Foot Disease In Geriatric Patients With Type 2 Diabetes, Eren İmre, Neşe Koçakgöl, Erdi̇ İmre

Turkish Journal of Medical Sciences

Background/aim: This study aims to reveal the prevalence of low handgrip strength in older patients with type 2 diabetes who have diabetic foot disease and to assess the association of handgrip strength with diabetic foot disease in older patients with type 2 diabetes. Materials and methods: Eighty-nine geriatric patients with diabetic foot ulcers and 69 patients without diabetic foot ulcers who presented to the endocrinology outpatient clinic between August 2020 and November 2021 were included in the study. The exclusion criteria were the usage of steroids, stroke-induced quadriplegia, myopathy, disability, hemodialysis treatment, type 1 diabetes, patients under 65 years of …

2022 Children's Legislative Report Card, Children's Advocacy Institute, University Of San Diego School Of Law

Children's Legislative Report Card

No abstract provided.

Orientation Online: The Surprising Benefits Of Virtual New Faculty Orientation, Kristin Herman, Patricia Davidson

STEMPS Faculty Publications

This design case documents the reimagination of new faculty orientation for a mid-sized public university due to the COVID-19 global pandemic. This fully virtual iteration was facilitated during the summer of 2020 and is compared both to previous in-person iterations of new faculty orientation as well as a blended modality version of the orientation program offered in 2021. The redesign is explained using language from Puntedura’s (2006) Substitution- Augmentation- Modification- Redefinition (SAMR) model of technology application in distributed learning. Such terminology provided a helpful common vocabulary for a design team pressured to determine which elements of orientation needed to be …

Bio-Clinical Evaluation Of Collateral Score In Acute Middle Cerebral Artery Occlusion, Esra Demi̇r, Hesna Bektaş, Hasan Bayindir, Oğuzhan Kurşun

Turkish Journal of Medical Sciences

Background/aim: Acute ischemic stroke (AIS) is characterized as a neurological deficit owing to an acute focal damage to the brain by cerebral infarction. A collateral score is the most significant factor evaluating the prognosis of AIS, its relationship with demographic data, serum biochemical parameters, and clinical disability in this field. Materials and methods: We conducted a single-center retrospective study with 100 patients with AIS within the first 6 h of ischemic stroke. Data for consecutive AIS patients were collected from February 2019 to May 2020. The collateral score was assessed by using developed scoring systems defined by Maas et al. …

Trace Mineral Source And Inclusion Level On Wean-To-Finish Pig Production, Marissa Larosae

Electronic Theses and Dissertations

Trace mineral requirements to optimize production for swine are not well defined, leading to excess trace mineral supplementation in swine diets and ultimately to excess trace minerals excreted in swine manure. Potential strategies to reduce the waste of excess trace minerals in diets include utilizing organic sources with higher bioavailability or reducing the overall trace mineral supplementation in the diet. Two studies were conducted in an effort to determine if utilizing organic trace minerals or reducing trace mineral inclusion into diets has an impact on overall performance measurements for nursery and grow-finish pigs, respectively. The first experiment utilized 1,144 weaned …

E. Coli Persister Cell Survival And Rhizobia Attachment To Soybean Roots, Tanim Islam

Electronic Theses and Dissertations

The theme of this thesis revolves around how bacteria respond and thrive during stress. Chapters 1-3 are about how bacteria deal with life-threatening antibiotics. Chapter 4 covers new research on how bacteria can move from a stressful individual lifestyle (free-living bacteria) to initiating a symbiotic relationship with a plant (a less stressful lifestyle). In Chapter 1, I briefly summarize the current state of knowledge in the field of antibiotic resistance and persistence. In Chapter 2, I add to this knowledge by providing new insights into several antibiotics' potency and exploring the antibiotic Eagle effect. In Chapter 3, I use pyruvate …

A Novel Crispr/Cas Gene Editing System For Plants Which Bypasses Genetic Transformation And Tissue Culture, Aastha Acharya

Electronic Theses and Dissertations

CRISPR/Cas system is a powerful gene-editing tool that has revolutionized gene editing in many ways. However, the current delivery methods for using CRISPR/Cas system inn plants have some drawbacks that have greatly limited their routine application in plant research and improvement. Specifically,, the methods heavily rely on either genetic transformation for delivering Cas and/or its gRNA coding sequences into the targeted cells or tissue culture, or both for recovering the whole edited plants. To overcome these drawbacks, we have developed a simple, easy to use yet effective system for CRISPR/Cas gene editing in plants that can bypass genetic transformation and …

Factors Associated With Unsafe Children's Stool Disposal: An Analysis From 2015-2016 Myanmar Demographic And Health Survey, Naw Lah Say Wah

Chulalongkorn University Theses and Dissertations (Chula ETD)

Introduction: Safe sanitation is essential for preventing the transmission of diarrhoeal diseases and other infections. Sanitation projects and programs targeted at household sanitation have paid little focus to the disposal of children's stools. Due to the common misconception of children’s stool as less infectious, parents improperly manage children's stools for disposal. Unsafe disposal of children's stools has become an unhindered part of public health problems primarily in low and middle-income countries. Objective: To identify the association between children's stool disposal methods and factors associated with unsafe children’s stool disposal methods in Myanmar Method: This study is the cross-sectional secondary data …

Hhs 3000 : Interprofessional Education In Collaborative Health And Human Services, Human Services

Approved Course Proposals

No abstract provided.