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Articles 47821 - 47850 of 239984
Full-Text Articles in Entire DC Network
Differences In Stronger Versus Weaker Firefighters In Selected Measures Of Power, Quincy Johnson, J. Jay Dawes, Melissa Uftring, Marcel Lopes Dos Santos, Davis Hale, Gabriel J. Sanders, Will Peveler, Roger O. Kollock
Differences In Stronger Versus Weaker Firefighters In Selected Measures Of Power, Quincy Johnson, J. Jay Dawes, Melissa Uftring, Marcel Lopes Dos Santos, Davis Hale, Gabriel J. Sanders, Will Peveler, Roger O. Kollock
Faculty Publications - Kinesiology and Recreation
Firefighters are required to perform a wide array of physically demanding job tasks, such as forcible entry, charged hose advances and victim extractions. An adequate level of muscular strength and power are required to successfully perform these tasks. The purpose of this study is to investigate the differences in stronger and weaker firefighters in measures of power. Archived data for twenty-seven (age = 34.3 ± 7.9 yr, body height = 176.3 ± 7.2 cm, body mass = 89.4 ± 15.7 kg) full-time firefighters were analyzed. Participants were placed into one of two groups [i.e., stronger (HIGH) (n = 13) …
The Collaborative Cross Strains And Their Founders Vary Widely In Cocaine-Induced Behavioral Sensitization., Sarah A Schoenrock, Leona H. Gagnon, Ashley A Olson, Michael Leonardo, Vivek M. Philip, Hao He, Laura G. Reinholdt, S J Sukoff Rizzo, James D Jentsch, Elissa J Chesler, Lisa M Tarantino
The Collaborative Cross Strains And Their Founders Vary Widely In Cocaine-Induced Behavioral Sensitization., Sarah A Schoenrock, Leona H. Gagnon, Ashley A Olson, Michael Leonardo, Vivek M. Philip, Hao He, Laura G. Reinholdt, S J Sukoff Rizzo, James D Jentsch, Elissa J Chesler, Lisa M Tarantino
Faculty Research 2022
Cocaine use and overdose deaths attributed to cocaine have increased significantly in the United States in the last 10 years. Despite the prevalence of cocaine use disorder (CUD) and the personal and societal problems it presents, there are currently no approved pharmaceutical treatments. The absence of treatment options is due, in part, to our lack of knowledge about the etiology of CUDs. There is ample evidence that genetics plays a role in increasing CUD risk but thus far, very few risk genes have been identified in human studies. Genetic studies in mice have been extremely useful for identifying genetic loci …
Piceatannol, A Dietary Polyphenol, Alleviates Adipose Tissue Loss In Pre-Clinical Model Of Cancer-Associated Cachexia Via Lipolysis Inhibition, Jonathan Kershaw, Bennett D. Elzey, Xiao-Xuan Guo, Kee-Hong Kim
Piceatannol, A Dietary Polyphenol, Alleviates Adipose Tissue Loss In Pre-Clinical Model Of Cancer-Associated Cachexia Via Lipolysis Inhibition, Jonathan Kershaw, Bennett D. Elzey, Xiao-Xuan Guo, Kee-Hong Kim
Public and Allied Health Faculty Publications
Cancer-associated cachexia (CAC) is the nutrition-independent loss of lean muscle and adipose tissues, and results in reduced chemotherapy effectiveness and increased mortality. Preventing adipose loss is considered a key target in the early stages of cachexia. Lipolysis is considered the central driver of adipose loss in CAC. We recently found that piceatannol, but not its analogue resveratrol, exhibits an inhibitory effect on lipolysis. The objective of this study was to investigate the role of piceatannol in cancer-associated lipolysis and cachexia-induced weight loss. Cancer cell-induced lipolysis in adipocytes was stimulated using cancer-conditioned media (CCM) or co-culture with human pancreatic cancer cells …
Gender Differences In The Relationships Between Perceived Stress, Eating Behaviors, Sleep, Dietary Risk, And Body Mass Index, Chen Du, Mary Adjepong, Megan Chong Hueh Zan, Min Jung Cho, Jennifer I. Fenton, Pao Ying Hsiao, Laura Keaver, Heesoon Lee, Mary-Jon Ludy, Wan Shen, Winnie Chee Siew Swee, Jyothi Thrivikraman, Felicity Amoah-Agyei, Emilie De Kanter, Wenyan Wang, Robin M. Tucker
Gender Differences In The Relationships Between Perceived Stress, Eating Behaviors, Sleep, Dietary Risk, And Body Mass Index, Chen Du, Mary Adjepong, Megan Chong Hueh Zan, Min Jung Cho, Jennifer I. Fenton, Pao Ying Hsiao, Laura Keaver, Heesoon Lee, Mary-Jon Ludy, Wan Shen, Winnie Chee Siew Swee, Jyothi Thrivikraman, Felicity Amoah-Agyei, Emilie De Kanter, Wenyan Wang, Robin M. Tucker
Public and Allied Health Faculty Publications
Background: Obesity is a growing epidemic among university students, and the high levels of stress reported by this population could contribute to this issue. Singular relationships between perceived stress; engagement in restrained, uncontrolled, and emotional eating; sleep; dietary risk; and body mass index (BMI) have been reported in the current body of literature; however, these constructs interact with each other, and the complex relationships among them are infrequently examined. Therefore, the aim of the present study was to explore the complex relationships between these constructs using mediation and moderation analyses stratified by gender. Methods: A cross-sectional study, enrolling university students …
Zephyrus, Western Kentucky University
Zephyrus, Western Kentucky University
Student Creative Writing
The fine arts magazine of Western Kentucky University at Bowling Green.
Media Infrastructure As Smart Power In The Case Of The Educational Film, Radio, And Television Center Of Turkey, 1949-1973, Aysehan Jülide Etem
Media Infrastructure As Smart Power In The Case Of The Educational Film, Radio, And Television Center Of Turkey, 1949-1973, Aysehan Jülide Etem
The Journal of e-Media Studies
This article identifies and examines how United States Information Services (USIS) agents developed, managed, funded, and sustained a media infrastructure to facilitate communication between the people and governments of the United States and Turkey. The central focus of this analysis is the Educational Film, Radio, and Television Center of Turkey (EFRTC; Film-Radyo ve Televizyonla Eğitim Merkezi), which in 1956 published a catalog featuring hundreds of films about the American way of life and only a handful of films about Turkish people. By analyzing declassified documents and previously unexamined primary materials gathered from archives in the United States and Turkey, this …
“Many People Have No Idea”: A Qualitative Analysis Of Healthcare Barriers Among Yazidi Refugees In The Midwestern United States, Falah N. Rashoka, Megan S. Kelley, Jeong‑Kyun Choi, Marc A. Garcia, Weiwen Chai, Hazim N. Rashawka
“Many People Have No Idea”: A Qualitative Analysis Of Healthcare Barriers Among Yazidi Refugees In The Midwestern United States, Falah N. Rashoka, Megan S. Kelley, Jeong‑Kyun Choi, Marc A. Garcia, Weiwen Chai, Hazim N. Rashawka
Department of Nutrition and Health Sciences: Faculty Publications
Background: The COVID-19 pandemic has shed new light on inequities in healthcare access faced by immigrant and refugee communities. To address ongoing disparities, there is an urgent need for ecological approaches to better understand the barriers that hinder and resources that facilitate access to healthcare. This study investigates barriers to healthcare system access faced by Yazidi refugees in the Midwestern United States.
Methods: Informed by the Interpretative Phenomenological Approach, three focus group meetings with a community advisory board were conducted between September 2019 and January 2020. The nine-member focus group included social workers, healthcare providers, and members of the Yazidi …
Twice-Exceptional Identification And Identity Formation: A Mixed Methods Study, Robin Goldin Tobin
Twice-Exceptional Identification And Identity Formation: A Mixed Methods Study, Robin Goldin Tobin
Electronic Theses and Dissertations
This research study examined the parent perceptions of and relationships among intellectual potential, academic achievement, and the order of identification of exceptionality for twice-exceptional students. Twice-exceptional students exhibit both giftedness and a learning disability or difference. Consistently and equitably identifying and serving twice-exceptional students is a persistent problem of practice in the field of education (Artiles et al., 2010; Gentry et al., 2019; List & Dykeman, 2019; Moon & Reis, 2004; Webb et al., 2019). This study was supported by a community partner, a private educational testing and advocacy agency in a Western state.
This mixed methods study utilized a …
Nebline, January/February 2022
Nebline, January/February 2022
NEBLINE Newsletter Archive from Nebraska Extension in Lancaster County
2021 Extension Highlights
Your Trusted Educational Resource
4-H Programs Engaged 24,313 Youth
A New Year, A New You, A Renewed Community by Emily Gratopp
Garden Guide: Things to Do This Month
Extension’s 2022 Master Gardener Training, Two Sites Available
Upcoming Green Industry Conferences
ProHort Lawn & Landscape Update
2022 Pesticide Applicator Trainings
Crop Production Clinics In-Person and Zoom
Heart of 4-H Volunteer Award: Phil Wharton and Jenny DeBuhr
Watch Chicks Hatch on Egg Cam
4-H Rabbit Show, March 19
Dog Club Accepting New Members, Starts Jan. 10
4-H Club Gives Youth With Special Needs Opportunity to Show Lambs
4-H Announcements …
Complexifying Paid Learning, 21cleo Research Team
Complexifying Paid Learning, 21cleo Research Team
21CLEO Research Project Blog Posts
No abstract provided.
Improving Antibiotic Administration Timing In Neonatal Early-Onset Sepsis, Donia B. Bass
Improving Antibiotic Administration Timing In Neonatal Early-Onset Sepsis, Donia B. Bass
Regis University Student Publications (comprehensive collection)
Abstract
Neonatal early onset sepsis (EOS) remains one of the most common causes of neonatal morbidity and mortality. Neonates requiring evaluation and treatment for suspected EOS inconsistently receive antibiotics within one hour of decision to treat as recommended in the 2012 neonatal sepsis guidelines by the National Institutes for Health and Care Excellence (NICE). A mixed method quality improvement initiative was employed in a level three NICU, applying a standardized admission process to mitigate systems flaws impacting delay of first dose antibiotic. A nursing sepsis education module was provided, and the novel SAM admission prioritization tool was developed to guide …
Contributions To The Knowledge Of The Diversity Of The Chewing Lice Fauna In Turkey, Gökhan Eren, Ömral Ünsal Özkoç, Mustafa Açici
Contributions To The Knowledge Of The Diversity Of The Chewing Lice Fauna In Turkey, Gökhan Eren, Ömral Ünsal Özkoç, Mustafa Açici
Turkish Journal of Zoology
The aim of the study was to identify the chewing lice which were sampled from the birds found dead during ornithological studies in the natural areas of Samsun, and transported to the laboratory of Ondokuz Mayıs University, Veterinary Faculty, Department of Parasitology, between 2018 and 2020. All samples were collected by ectoparasite examination. The collected lice specimens were preserved in tubes with 70% alcohol. The specimens were cleared in 10% KOH for 24 h before being mounted in Canada balsam and identified under the light microscope. A total of 35 species under 3 families were detected in this study: Menoponidae: …
Soil Resilience And Arbuscular Mycorrhizal Fungi: How Fungi Can Inform Climate Change Mitigation And Adaptation In Maya Milpa Management, Courtney Mathers
Soil Resilience And Arbuscular Mycorrhizal Fungi: How Fungi Can Inform Climate Change Mitigation And Adaptation In Maya Milpa Management, Courtney Mathers
Electronic Theses and Dissertations
In Mexico’s state of Yucatán, climate change impacts like prolonged and less predictable dry season length are manifesting as threats to agricultural production and food security. Nearly two thirds of Yucatán’s population is indigenous, many of whom live in rural communities that rely on rainfed subsistence agriculture (INEGI 2015). Ensuring sufficient food production in the face of climate change relies on the quality of agricultural soils. With both mismanagement of agricultural soils and climate change posing as threats to food production in Mexico, soil management practices that increase a soil quality should be identified and promoted. The primary objective of …
Understanding Perceptions Of Social Eating During Lunch For Adolescents With Anorexia Nervosa: An Instrumental Case Study, Madelyn Duzyk
Understanding Perceptions Of Social Eating During Lunch For Adolescents With Anorexia Nervosa: An Instrumental Case Study, Madelyn Duzyk
Occupational Therapy Doctorate Capstone Projects
Background: Current literature on adolescents with Anorexia Nervosa (AN) show that social participation is a key factor of community reintegration and long-term recovery (Mekori et al., 2017; Preyde et al., 2017); however, there is little known about the impact of social eating for adolescents with AN.
Purpose: The purpose of this instrumental case study is to more fully understand the meaning of social eating during lunch for adolescents with AN and begin to illustrate social eating’s impact on treatment, community re-integration, and long-term remission.
Methods: A qualitative case-study methodology was developed to gain perceptions of social eating from adolescents with …
Ms Environmental Biology Capstone Project, Catherine Shapiro
Ms Environmental Biology Capstone Project, Catherine Shapiro
Regis University Student Publications (comprehensive collection)
Chapter 1: Artificial light at night disrupts the biology of fishes. Chapter 2: Grant proposal to determine how artificial light at night affects Pumpkinseed fish. Chapter 3: Management of pinyon-juniper woodland impacts the occupancy of Pinyon Jays. Chapter 4: Stakeholder analysis of horseshoe crab fishing and its impacts on the Red Knot and biomedical industry.
Ending ‘Period Poverty’: A Holistic Proposal To Address Menstrual Hygiene Management For People Experiencing Homelessness In Denver, Colorado., Emily Weber
Regis University Student Publications (comprehensive collection)
This proposal is for a holistic, community-based approach to MHM, with a specific focus on people experiencing homelessness in Denver, Colorado. The proposal culminates in a holistic set of recommendations, including both actionable items and systems- and policy- level suggestions, to improve access to clean and dignified MHM for the intended beneficiaries.
The goals of this proposal are to: 1) Increase community collaboration on addressing MHM; 2) Provide equitable access to MHM products for all people experiencing homelessness; 3) Reduce the stigma associated with MHM; 4) Provide safe, private, and clean spaces for dignified MHM in Denver; and 5) Create …
Bill Gatton College Of Pharmacy Viewbook - 2022, Bill Gatton College Of Pharmacy, East Tennessee State University
Bill Gatton College Of Pharmacy Viewbook - 2022, Bill Gatton College Of Pharmacy, East Tennessee State University
Bill Gatton College of Pharmacy Miscellaneous Publications
No abstract provided.
Modulation Of Human Gut Microbiota Through Dietary Associations, Sumudu Sasanka Rajakaruna
Modulation Of Human Gut Microbiota Through Dietary Associations, Sumudu Sasanka Rajakaruna
Browse all Theses and Dissertations
Study of human gut microbiota is becoming widely popular in recent years, especially due to numerous beneficial aspects attributed to this diverse and complex microbial communities. Followingly, there is a keen interest in understanding the dynamics and subsequent modulation of human gut microbiota, from a health perspective. Diet is considered significant in shaping gut microbiota community and functions, predominantly due to dietary macro and micronutrient content. Subsequently, a plethora of research is carried out on the effects of dietary nutrients on gut microbiota. Dietary patterns, quality of the diet, differences in food preparation methods, physiological and chemical changes occurred during …
Heterogeneity Of Diabetes: B-Cells, Phenotypes, And Precision Medicine: Proceedings Of An International Symposium Of The Canadian Institutes Of Health Research’S Institute Of Nutrition, Metabolism And Diabetes And The U.S. National Institutes Of Health’S National Institute Of Diabetes And Digestive And Kidney Diseases, William T. Cefalu, Dana K. Andersen, Guillermo Arreaza-Rubín, Christopher L. Pin, Sheryl Sato, C. Bruce Verchere, Minna Woo, Norman D. Rosenblum
Heterogeneity Of Diabetes: B-Cells, Phenotypes, And Precision Medicine: Proceedings Of An International Symposium Of The Canadian Institutes Of Health Research’S Institute Of Nutrition, Metabolism And Diabetes And The U.S. National Institutes Of Health’S National Institute Of Diabetes And Digestive And Kidney Diseases, William T. Cefalu, Dana K. Andersen, Guillermo Arreaza-Rubín, Christopher L. Pin, Sheryl Sato, C. Bruce Verchere, Minna Woo, Norman D. Rosenblum
Paediatrics Publications
One hundred years have passed since the discovery of insulin—an achievement that transformed diabetes from a fatal illness into a manageable chronic condition. The decades since that momentous achievement have brought ever more rapid innovation and advancement in diabetes research and clinical care. To celebrate the important work of the past century and help to chart a course for its continuation into the next, the Canadian Institutes of Health Research’s Institute of Nutrition, Metabolism and Diabetes and the U.S. National Institutes of Health’s National Institute of Diabetes and Digestive and Kidney Diseases recently held a joint international symposium, bringing together …
Accuracy And Practical Considerations For Doubly Labeled Water Analysis In Nutrition Studies Using A Laser-Based Isotope Instrument (Off-Axis Integrated Cavity Output Spectroscopy), Linda M. Reynard, William W. Wong, Noreen Tuross
Accuracy And Practical Considerations For Doubly Labeled Water Analysis In Nutrition Studies Using A Laser-Based Isotope Instrument (Off-Axis Integrated Cavity Output Spectroscopy), Linda M. Reynard, William W. Wong, Noreen Tuross
Geosciences Faculty Publications and Presentations
Background: Given the utility of the doubly labeled water (DLW) method for determination of energy expenditure, additional techniques for isotope analysis of the samples are welcome. Laser-based instruments are one such new analytical tool, but their accuracy and feasibility for DLW studies are grossly understudied.
Objectives: We assessed the accuracy of laser-based isotope ratio measurements as part of the DLW method for estimation of carbon dioxide production rate (rCO2) and total energy expenditure (TEE), in between-group comparison study designs.
Methods: Urine samples from a previous study were analyzed with a laser-based instrument [off-axis integrated cavity output spectroscopy (OA-ICOS)]. …
Ms Environmental Biology Capstone Project, Tyler Erickson
Ms Environmental Biology Capstone Project, Tyler Erickson
Regis University Student Publications (comprehensive collection)
1. Impacts of Trout Stocking Practices on Colorado’s Alpine Ecosystems
2. Effects of Trout Presence on Alpine Lake Macroinvertebrate Emergence in Colorado
3. Post-Stocking Survival and Myxospore Evaluation of Whirling Disease Resistant Rainbow Trout Strains
4. A Compromise for the Planned Reservoir Expansion at Bear Creek Lake Park to Combat Denver’s Water Crisis
Social Cognitive Outcomes Are Associated With Improvements In Mobility Performance Following Lifestyle Intervention In Prostate Cancer Patients Undergoing Androgen Deprivation Therapy, Zachary L. Chaplow, Alexander R. Lucas, Elizabeth Grainger, Christina Simpson, Ciaran M. Fairman, Victoria R. Descenza, Jessica Bowman, Steven K. Clinton, Brian C. Focht
Social Cognitive Outcomes Are Associated With Improvements In Mobility Performance Following Lifestyle Intervention In Prostate Cancer Patients Undergoing Androgen Deprivation Therapy, Zachary L. Chaplow, Alexander R. Lucas, Elizabeth Grainger, Christina Simpson, Ciaran M. Fairman, Victoria R. Descenza, Jessica Bowman, Steven K. Clinton, Brian C. Focht
Health Policy Publications
Objective
To compare the effects of an exercise and dietary intervention with those of standard-of-care management upon change in lift and carry performance and mobility-related self-efficacy beliefs and explore associations in prostate cancer patients undergoing androgen deprivation therapy.
Methods
32 prostate cancer patients (M age = 66.2 years; SD = 7.8) undergoing androgen deprivation therapy were randomly assigned to a 3-month exercise and dietary lifestyle intervention (n = 16) or standard-of-care management (n = 16). Outcome assessments were obtained at baseline, 2- and 3-month follow-up.
Results
The lifestyle intervention resulted in significantly greater improvements in lift and …
Ua19/16/2 Soccer Press Releases, Wku Athletic Media Relations
Ua19/16/2 Soccer Press Releases, Wku Athletic Media Relations
WKU Administration Documents
Press releases, photos and game statistics for WKU soccer team in 2022.
Association Between Periodontal Disease And Oral Cancer Screening Among Us Adults: Nhanes 2011-2014, Shillpa Naavaal, Dina T. Garcia, Xiaoyan Deng, Dipankar Bandyopadhya
Association Between Periodontal Disease And Oral Cancer Screening Among Us Adults: Nhanes 2011-2014, Shillpa Naavaal, Dina T. Garcia, Xiaoyan Deng, Dipankar Bandyopadhya
Dental Public Health and Policy Publications
Objectives:
To examine oral cancer screening rates and associated factors among adults with periodontal disease (PD). We hypothesized that adults with severe PD will be less likely to report receipt of any type of oral cancer screening than adults with no PD.
Materials and Methods:
We used 2011-2014 National Health and Nutrition Examination Survey (NHANES) data on adults ≥ 30 years. PD status was classified as no PD, mild/moderate PD, and severe PD. Survey-adjusted logistic regression analysis was used to examine the model adjusted risk ratio (RR) and 95% confidence intervals (CI) for the outcome of not receiving intraoral, extraoral …
Improving Self-Care Awareness Among Undergraduate Nursing Students, D'Anna Helms
Improving Self-Care Awareness Among Undergraduate Nursing Students, D'Anna Helms
Doctor of Nursing Practice Projects
The purpose of this DNP project was to improve self-care (SC) awareness among undergraduate nursing students by educating on the use of constructive SC activities. Twenty-two senior level nursing students attended an educational seminar, completed the Mindful Self-Care Scale – Clinical (MSCS-C) pre- and post-survey, and reflective journaling. A paired-samples t test was calculated to compare the mean pretest score to the mean posttest score. The mean on the pretest was 77.68 (sd= 9.33), and the mean on the posttest was 75.27 (sd= 31.59). A significant increase from pretest to posttest was found (t (21) = .307, p < .05). Thematical analysis revealed enhanced awareness and incorporation of constructive SC activities. Educational interventions which seek to improve SC awareness will generate practical and sustainable acts of SC, thus improving students’ overall success and further empowering students in their transition from graduate to licensed nurses.
Decolorization Of Synthetic Textile Dyes By Fungal Endophytes Isolated From The Leaves Of Philippine Mangrove (Avicennia Marina), Steve P. Obanan, Resureccion B. Sadaba, Pamela Alva-Gatchalian, Annabelle V. Cadiz, Evelyn M. Basilio, Dennis B. Bela-Ong
Decolorization Of Synthetic Textile Dyes By Fungal Endophytes Isolated From The Leaves Of Philippine Mangrove (Avicennia Marina), Steve P. Obanan, Resureccion B. Sadaba, Pamela Alva-Gatchalian, Annabelle V. Cadiz, Evelyn M. Basilio, Dennis B. Bela-Ong
Biology Faculty Publications
Textile dyes in wastewater can be harmful pollutants when released into the environment without treatment. Biodegradation of textile dye effluents by different microbes, including fungi, has become popular as an alternative to physicochemical methods. The mangrove Avicennia marina is known to harbor endophytic fungi which have the potential to carry out dye degradation. Therefore, this study assessed the ability to decolorize synthetic dyes of endophytic fungi isolated from the leaves of A. marina. Of the nine fungal endophytes, Aspergillus niger, Syncephalastrum racemosum and Penicillium citrinum exhibited the highest mycelial growths in solid media, while all endophytes adsorbed Congo red. Through …
Privacy In Wearables: Innovation, Regulation, Or Neither, Kenny Gutierrez
Privacy In Wearables: Innovation, Regulation, Or Neither, Kenny Gutierrez
UC Law Science and Technology Journal
No abstract provided.
Feeding Memories: A Conversation With Writers Who Write About Food, Rochelle Spencer, Tara Christina, Dera R. Williams, Shannon Holbrook
Feeding Memories: A Conversation With Writers Who Write About Food, Rochelle Spencer, Tara Christina, Dera R. Williams, Shannon Holbrook
Publications and Research
Rochelle Spencer interviews Tara Christina, a writer and educator with degrees in holistic nutrition and is the founder and CEO of Tara’s Teas, an artisanal line of organic, loose leaf tea blends; Dera R. Williams whose work appears in several anthologies and you can find her food-related writing on her blog; and Shannon Holbrook, a writer and wine and food consultant who has organized prominent food-writing events throughout the Bay Area.
Cone Of Gaze In Schizotypy: Potential Differences Among Positive, Negative, And Disorganized Subtypes, Courtney N. Wiesepape
Cone Of Gaze In Schizotypy: Potential Differences Among Positive, Negative, And Disorganized Subtypes, Courtney N. Wiesepape
All-Inclusive List of Electronic Theses and Dissertations
Although not as prevalent as other disorders, the impact of schizophrenia is widespread and costly. Societal burden and individual suffering provide support for increased focus on the early identification of individuals at risk for developing schizophrenia spectrum disorders. Utilizing the construct of schizotypy is one method of studying the early onset of these disorders. Meehl (1962; 1990) introduced the concept of schizotypy as personality organization that results in increased vulnerability to develop schizophrenia spectrum disorders. Thus, individuals psychometrically identified to be schizotypes present a unique opportunity to study the factors that contribute to the development of schizophrenia spectrum disorders. In …
The Role Of Cyclic Di Amp In Speb Virulence And Pathogenesis In Streptococcus Pyogenes, Sabrina Faozia
The Role Of Cyclic Di Amp In Speb Virulence And Pathogenesis In Streptococcus Pyogenes, Sabrina Faozia
All-Inclusive List of Electronic Theses and Dissertations
The second messenger molecule, c-di-AMP, plays a critical role in pathogenesis and virulence in group A Streptococcus or S. pyogenes. However, relatively little is known about its underlying molecular mechanisms in the c-di-AMP signal transduction pathways. This study aims to understand the role of c-di-AMP in SpeB virulence regulation and pathogenesis to decipher the c-di-AMP signaling mechanism in S. pyogenes. SpeB is one of the major virulence factors crucial for the pathogenesis of severe invasive GAS diseases. It is a cysteine protease that can cleave host proteins and own surface proteins. In S. pyogenes, c-di-AMP is synthesized by a diadenylate …