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Using Daily Learning Objectives To Guide Teaching And Assessment With Chris Estepp -New Faculty Lunch Discussion, Chris Estepp Feb 2022

Using Daily Learning Objectives To Guide Teaching And Assessment With Chris Estepp -New Faculty Lunch Discussion, Chris Estepp

TFSC Publications and Presentations

Daily learning objectives should drive instruction and assessment. This talk will discuss creating measurable, student-centered objectives and how to create assessments that can effectively measure student learning.


Appendix: Cannabis, Consumers, And The Trademark Laundering Trap, Viva R. Moffat, Sam Kamin, Tim Maffett Feb 2022

Appendix: Cannabis, Consumers, And The Trademark Laundering Trap, Viva R. Moffat, Sam Kamin, Tim Maffett

William & Mary Law Review Online

Appendix to article in William & Mary Law Review vol. 63, no. 6 (2022), "Cannabis, Consumers, and the Trademark Laundering Trap" by Viva R. Moffat, Sam Kamin, and Tim Maffett.


Clemson Trustees Minutes, 2022 February 2, Clemson University Board Of Trustees Feb 2022

Clemson Trustees Minutes, 2022 February 2, Clemson University Board Of Trustees

Minutes

No abstract provided.


Comparison Of Human Urinary Exosomes Isolated Via Ultracentrifugation Alone Versus Ultracentrifugation Followed By Sec Column-Purification, Kun Huang, Sudha Garimella, Alyssa Clay-Gilmour, Lucia Vojtech, Bridget Armstrong, Madison Bessonny, Alexis Stamatikos Feb 2022

Comparison Of Human Urinary Exosomes Isolated Via Ultracentrifugation Alone Versus Ultracentrifugation Followed By Sec Column-Purification, Kun Huang, Sudha Garimella, Alyssa Clay-Gilmour, Lucia Vojtech, Bridget Armstrong, Madison Bessonny, Alexis Stamatikos

Faculty Publications

Chronic kidney disease is a progressive, incurable condition that involves a gradual loss of kidney function. While there are no non-invasive biomarkers available to determine whether individuals are susceptible to developing chronic kidney disease, small RNAs within urinary exosomes have recently emerged as a potential candidate to use for assessing renal function. Ultracentrifugation is the gold standard for urinary exosome isolation. However, extravesicular small RNA contamination can occur when isolating exosomes from biological fluids using ultracentrifugation, which may lead to misidentifying the presence of certain small RNA species in human urinary exosomes. Therefore, we characterized human urinary exosomal preparations isolated …


February 2, 2022 Faculty Senate Minutes, University Of South Carolina Feb 2022

February 2, 2022 Faculty Senate Minutes, University Of South Carolina

Faculty Senate

No abstract provided.


Assessing Early Use And Complications Of Gastrostomy Blended Feeds, James Fraser, Shai Stewart Md, Kristen L. Sayers, Amy L. Pierce, Beth A. Orrick, Kayla B. Briggs, Wendy Jo Svetanoff, Tolulope A. Oyetunji Md Mph, Shawn D. St Peter, Richard J. Hendrickson Feb 2022

Assessing Early Use And Complications Of Gastrostomy Blended Feeds, James Fraser, Shai Stewart Md, Kristen L. Sayers, Amy L. Pierce, Beth A. Orrick, Kayla B. Briggs, Wendy Jo Svetanoff, Tolulope A. Oyetunji Md Mph, Shawn D. St Peter, Richard J. Hendrickson

Presentations

No abstract provided.


Effects Of Metformin Combined With Antifolates On Hepg2 Cell Metabolism And Cellular Proliferation, Sherouk M. Tawfik, Maha R.A. Abdollah, M. M. Elmazar, Hassan A. N. El-Fawal, Anwar Abdelnaser Feb 2022

Effects Of Metformin Combined With Antifolates On Hepg2 Cell Metabolism And Cellular Proliferation, Sherouk M. Tawfik, Maha R.A. Abdollah, M. M. Elmazar, Hassan A. N. El-Fawal, Anwar Abdelnaser

Pharmacy

Hepatocellular carcinoma (HCC), one of the most prevalent types of cancers worldwide, continues to maintain high levels of resistance to standard therapy. As clinical data revealed poor response rates, the need for developing new methods has increased to improve the overall wellbeing of patients with HCC. Furthermore, a growing body of evidence shows that cancer metabolic changes are a key feature of many types of human malignancies. Metabolic reprogramming refers to cancer cells’ ability to change their metabolism in order to meet the increased energy demand caused by continuous growth, rapid proliferation, and other neoplastic cell characteristics. For these reasons, …


Evaluating A Multicomponent Survivorship Programme For Men With Prostate Cancer In Australia: A Single Cohort Study, Patsy Yates, Rob Carter, Robyn Cockerell, Donna Cowan, Cyril Dixon, Anita Lal, Robert U. Newton, Nicolas Hart, Daniel A. Galvão, Brenton Baguley, Nicholas Denniston, Tina Skinner, Jeremy Couper, Jon Emery, Mark Frydenberg, Wei Hong Liu Feb 2022

Evaluating A Multicomponent Survivorship Programme For Men With Prostate Cancer In Australia: A Single Cohort Study, Patsy Yates, Rob Carter, Robyn Cockerell, Donna Cowan, Cyril Dixon, Anita Lal, Robert U. Newton, Nicolas Hart, Daniel A. Galvão, Brenton Baguley, Nicholas Denniston, Tina Skinner, Jeremy Couper, Jon Emery, Mark Frydenberg, Wei Hong Liu

Research outputs 2022 to 2026

Objective: To evaluate the implementation of a multicomponent survivorship programme for men with prostate cancer and their carers. Design: A single cohort study, guided by the RE-AIM framework. Setting: Multiple health services in Australia. Participants: Men with prostate cancer and their carers, and health professionals. Intervention: A 12-month telehealth programme that provided centralised and coordinated decision and information support, exercise and nutrition management, specialised clinical support and practical support to men and their carers. Data collection: Multiple sources of data including participant-reported health outcomes and experience of care, qualitative interviews, records of the programme were collected at different time points. …


Similar Mortality Among United States Veterans With Invasive And Noninvasive Pneumonia Due To Group B Streptococcus, Brigid M. Wilson, Sunah Song, Robin L.P. Jump, Federico Perez Feb 2022

Similar Mortality Among United States Veterans With Invasive And Noninvasive Pneumonia Due To Group B Streptococcus, Brigid M. Wilson, Sunah Song, Robin L.P. Jump, Federico Perez

Faculty Scholarship

Background: The nosology of noninvasive pneumonia due to group B Streptococcus (GBS) is not well defined. This study compared clinical characteristics and outcomes of patients with invasive pneumonia and noninvasive pneumonia caused by GBS. Methods: We conducted a retrospective cohort study among Veterans Affairs (VA) healthcare users between 2008 and 2017. Using data from electronic health records, we identified patients who had blood or respiratory cultures that grew GBS and had invasive pneumonia or noninvasive pneumonia. We analyzed patient and infection characteristics associated with all-cause mortality, including among the subset of patients with cultures that were monomicrobial for GBS. Results: …


Compounding Inequalities: Adolescent Psychosocial Wellbeing And Resilience Among Refugee And Host Communities In Jordan During The Covid-19 Pandemic, Nicola Jones, Sarah Baird, Bassam Abu Hamad, Zulfiqar Ahmed Bhutta, Erin Oakley, Manisha Shah, Jude Sajdi, Kathryn M. Yount Feb 2022

Compounding Inequalities: Adolescent Psychosocial Wellbeing And Resilience Among Refugee And Host Communities In Jordan During The Covid-19 Pandemic, Nicola Jones, Sarah Baird, Bassam Abu Hamad, Zulfiqar Ahmed Bhutta, Erin Oakley, Manisha Shah, Jude Sajdi, Kathryn M. Yount

Department of Paediatrics and Child Health

Purpose: The COVID-19 pandemic and associated risk-mitigation strategies have altered the social contexts in which adolescents in low- and middle-income countries live. Little is known, however, about the impacts of the pandemic on displaced populations, and how those impacts differ by gender and life stage. We investigate the extent to which the pandemic has compounded pre-existing social inequalities among adolescents in Jordan, and the role support structures play in promoting resilience.
Methods: Our analysis leverages longitudinal quantitative survey data and in-depth qualitative interviews, collected before and after the onset of COVID-19, with over 3,000 Syrian refugees, stateless Palestinians and vulnerable …


Nutritional Status And Dietary Intake Of School-Age Children And Early Adolescents: Systematic Review In A Developing Country And Lessons For The Global Perspective, Durray Shahwar Abid Khan, Jai K. Das, Shagufta Zareen, Zohra S. Lassi, Afsah Salman, Muhammad Raashid, Aftab A. Dero, Aijaz Khanzada, Zulfiqar Ahmed Bhutta Feb 2022

Nutritional Status And Dietary Intake Of School-Age Children And Early Adolescents: Systematic Review In A Developing Country And Lessons For The Global Perspective, Durray Shahwar Abid Khan, Jai K. Das, Shagufta Zareen, Zohra S. Lassi, Afsah Salman, Muhammad Raashid, Aftab A. Dero, Aijaz Khanzada, Zulfiqar Ahmed Bhutta

Department of Paediatrics and Child Health

Background: The prevalence of double burden of malnutrition (DBM) is high in low- and middle-income countries (LMICs). Data on malnutrition trends is present for children age, however the data for school-going children and adolescents aged 5-15 years is scarce.
Objective: This systematic review presents the pooled prevalence of nutritional status and dietary intake among school-going children and adolescents (5-15 years of age) in an LMIC of Pakistan and the perspective for broader global nutrition in this age group.
Methods: An electronic search of databases was run on Pubmed and Medline (via Ovid) along with gray literature and archives of local …


Effects Of Seasonal Rest Grazing And Diet Selection Of Sheep On Pasture Composition In Bromus Inermis Improved Meadow Steppe, H. Zhang, Y. J. Zhang, N. Liu Feb 2022

Effects Of Seasonal Rest Grazing And Diet Selection Of Sheep On Pasture Composition In Bromus Inermis Improved Meadow Steppe, H. Zhang, Y. J. Zhang, N. Liu

IGC Proceedings (1977-2023)

To develop sustainable grazing management systems based on highly-productive dominant species, it is critical to maintain pasture growth and prevent land degradation on meadow steppe. A field study was performed to identify the impact of seasonal rest grazing on diet selection of sheep and pasture composition in Bromus inermis improved meadow steppe from 2015 to 2017 in Hulunbuir, Inner Mongolia, China. Three seasonal rest grazing strategies were conducted: R1 included a spring rest from June 15 to July 15, R2 a summer rest from July 15 to August 15 and R3 an autumn rest from August 15 to September 15. …


The Effect Of Hay Supplementation On Performance Of Grazing Alpaca In The Peruvian Andes, M. Enciso, C. Gómez, C. Osorio Feb 2022

The Effect Of Hay Supplementation On Performance Of Grazing Alpaca In The Peruvian Andes, M. Enciso, C. Gómez, C. Osorio

IGC Proceedings (1977-2023)

Productivity of alpaca grazing rangelands in the Andes is often limited by the low availability and quality of those pastures during the dry season of the year. The use as supplements of forages cultivated during the rainy season in appropriate areas in the Andes may be a strategy to improve performance of alpacas. Therefore, the supplementation of oat-vetch pellets or oat hay was evaluated and compared with a control group without supplementation. Sixty three female alpacas (15 months of age, 34 ± 1.0 kg BW), divided in three groups, grazing range pastures (6.1% crude protein and 61.3% NDF) during dry …


Surgical Methods Of Obesity Treatments For Lowering Body Mass Index, Barno Kh. Shagazatova, Oktyabr R. Teshaev, Nasiba A. Kudratova, Umid S. Ruziev Feb 2022

Surgical Methods Of Obesity Treatments For Lowering Body Mass Index, Barno Kh. Shagazatova, Oktyabr R. Teshaev, Nasiba A. Kudratova, Umid S. Ruziev

Central Asian Journal of Medicine

Introduction. In connection with the upward trend in the number of obese people, new approaches to the treatment of obesity are being explored. Surgical methods of treating severe obesity have become widely used throughout the world in recent decades. The main task of such methods is to influence the course of diseases associated with obesity (bariatric surgery) by means of a significant decrease in body mass. Material and methods. We studied 72 obese patients who were divided into 2 groups depending on the degree of obesity. In each group, in order to reduce body weight, 3 types of surgical interventions …


The Mechanism Of Methodological Improvement Of Professional And Pedagogical Competence Of Future Medical Teachers, Feruza K. Iskandjanova Feb 2022

The Mechanism Of Methodological Improvement Of Professional And Pedagogical Competence Of Future Medical Teachers, Feruza K. Iskandjanova

Central Asian Journal of Medicine

Professional competence is a person's ability to perform professional duties. Professionalism is made up of many professional competencies. Competence includes the ability to use these skills depending on their knowledge, skills and abilities. In the context of deepening the content of pedagogical and information technologies, the key to the success of any doctor-teacher in the field of professional activity is an approach to the methodological improvement of his professional, pedagogical and information competence.


Morphological Changes In The Long Tubular Bones Of Rats In Experimental Osteoporosis, Mardon I. Ollaberganov, Rashid Y. Ruzibaev, Guzal I. Madaminova Feb 2022

Morphological Changes In The Long Tubular Bones Of Rats In Experimental Osteoporosis, Mardon I. Ollaberganov, Rashid Y. Ruzibaev, Guzal I. Madaminova

Central Asian Journal of Medicine

After gastric resection, most patients experience serious digestive disorders, a decrease in body weight [1] and the appearance of severe clinical manifestations of a number of diseases [10]. The gastrointestinal tract (GIT), as one of the subsystems of bone mineral metabolism, takes an active part in maintaining the age-related bone mass constant [4]. In diseases of the gastrointestinal tract, the absorption of minerals and vitamins (including Ca and vitamin D) is impaired. This leads to a decrease in the calcium content in bone tissue, a decrease in bone mineral density (BMD) – osteoporosis [6]. In our study, the experimental condition …


The Effect Of Pain Tolerance On Healthcare Utilization Among Patients With Chronic Pain, Callie Rose Teufert Feb 2022

The Effect Of Pain Tolerance On Healthcare Utilization Among Patients With Chronic Pain, Callie Rose Teufert

Theses and Dissertations

Chronic pain patients are more likely to use healthcare services and have greater expenditures related to health needs, which has led to studies on different aspects of pain that may lead to greater use, disability, functional impairment, and other outcomes. Factors that have been researched for their potential relationships with healthcare utilization (HCU) in various populations include function loss, pain catastrophizing, anxiety, fear, pain severity, and pain duration. Pain tolerance has not been extensively studied for its impact on healthcare utilization among patients with chronic pain. This study examined the relationship between perceived pain tolerance in chronic pain patients and …


A Multitarget Approach To Evaluate The Efficacy Of Aquilaria Sinensis Flower Extract Against Metabolic Syndrome, Hee Sung Chae, Olivia Dale, Tahir Maqbool Mir, Bharathi Avula Feb 2022

A Multitarget Approach To Evaluate The Efficacy Of Aquilaria Sinensis Flower Extract Against Metabolic Syndrome, Hee Sung Chae, Olivia Dale, Tahir Maqbool Mir, Bharathi Avula

Faculty and Student Publications

Aquilaria sinensis (Lour.) Spreng is known for its resinous secretion (agarwood), often secreted in defense against injuries. We investigated the effects of A. sinensis flower extract (AF) on peroxisome proliferator-activated receptors alpha and gamma (PPARα and PPARγ), liver X receptor (LXR), glucose uptake, and lipid accumulation (adipogenesis). Activation of PPARα, PPARγ and LXR was determined in hepatic (HepG2) cells by reporter gene assays. Glucose uptake was determined in differentiated muscle (C2C12) cells using 2-NBDG (2-deoxy-2-[(7-nitro-2,1,3-benzoxadiazol-4-yl)amino]-D-glucose). Adipogenesis was determined in adipocytes (3T3-L1 cells) by Oil red O staining. At a concentration of 50 µg/mL, AF caused 12.2-fold activation of PPARα and …


Head And Neck Cancer Survivorship Consensus Statement From The American Head And Neck Society, Neerav Goyal, Andrew Day, Joel Epstein, Joseph Goodman, Evan Graboyes, Scharukh Jalisi, Ana P Kiess, Jamie A Ku, Matthew C Miller, Aru Panwar, Vijay A Patel, Assuntina Sacco, Vlad Sandulache, Amy M. Williams, Daniel Deschler, D. Gregory Farwell, Cherie-Ann Nathan, Carole Fakhry, Nishant Agrawal Feb 2022

Head And Neck Cancer Survivorship Consensus Statement From The American Head And Neck Society, Neerav Goyal, Andrew Day, Joel Epstein, Joseph Goodman, Evan Graboyes, Scharukh Jalisi, Ana P Kiess, Jamie A Ku, Matthew C Miller, Aru Panwar, Vijay A Patel, Assuntina Sacco, Vlad Sandulache, Amy M. Williams, Daniel Deschler, D. Gregory Farwell, Cherie-Ann Nathan, Carole Fakhry, Nishant Agrawal

Otolaryngology Articles

Objectives: To provide a consensus statement describing best practices and evidence regarding head and neck cancer survivorship.

Methods: Key topics regarding head and neck cancer survivorship were identified by the multidisciplinary membership of the American Head and Neck Society Survivorship, Supportive Care & Rehabilitation Service. Guidelines were generated by combining expert opinion and a review of the literature and categorized by level of evidence.

Results: Several areas regarding survivorship including dysphonia, dysphagia, fatigue, chronic pain, intimacy, the ability to return to work, financial toxicity, lymphedema, psycho-oncology, physical activity, and substance abuse were identified and discussed. Additionally, the group identified and …


“A New Face Of Loreto”: Mission And Transformation In The Post-Vatican Ii Church, Sudha Arul Feb 2022

“A New Face Of Loreto”: Mission And Transformation In The Post-Vatican Ii Church, Sudha Arul

Jesuit School of Theology Dissertations

This dissertation documents the transformation of mission and ministry undertaken by the Sisters of Loreto in Kolkata, India, over the past 180 years. This IBVM congregation, self-defined as a dynamic community of women dedicated to social justice and empowering the poor and marginalized, has embraced a radical new focus on direct service to unhoused children who live on the streets. The renewal is rooted in the charism and spirituality of Mary Ward (1585-1645), foundress of the Loreto community, who, at a time when women religious were required to live in monastic enclosure, sought a new apostolic form of religious life …


Ranking The Biases: The Choice Of Otus Vs. Asvs In 16s Rrna Amplicon Data Analysis Has Stronger Effects On Diversity Measures Than Rarefaction And Otu Identity Threshold, Marlène Chiarello, Mark Mccauley, Sébastien Villéger, Colin R. Jackson Feb 2022

Ranking The Biases: The Choice Of Otus Vs. Asvs In 16s Rrna Amplicon Data Analysis Has Stronger Effects On Diversity Measures Than Rarefaction And Otu Identity Threshold, Marlène Chiarello, Mark Mccauley, Sébastien Villéger, Colin R. Jackson

Faculty and Student Publications

Advances in the analysis of amplicon sequence datasets have introduced a methodological shift in how research teams investigate microbial biodiversity, away from sequence identity-based clustering (producing Operational Taxonomic Units, OTUs) to denoising methods (producing amplicon sequence variants, ASVs). While denoising methods have several inherent properties that make them desirable compared to clustering-based methods, questions remain as to the influence that these pipelines have on the ecological patterns being assessed, especially when compared to other methodological choices made when processing data (e.g. rarefaction) and computing diversity indices. We compared the respective influences of two widely used methods, namely DADA2 (a denoising …


A Multiple Case Study Of Oregon’S K-12 Accountability Transformation: A Journey To Include Outcome Mapping, Shay Mikalson Feb 2022

A Multiple Case Study Of Oregon’S K-12 Accountability Transformation: A Journey To Include Outcome Mapping, Shay Mikalson

Doctor of Education (EdD)

This multiple case study investigated the experiences of three Oregon K-12 educational leaders and their perspectives on the potential of Outcome Mapping, through the implementation of the Student Success Act, as a catalyst for improved statewide accountability and increased academic achievement for Oregon's students. Outcome Mapping is a theory-driven model developed from the "black box" problem in accountability that focuses its measurement on the process by which change occurs, instead of just the results of the change, attempting to ultimately link cause and effect relationships. Few previous studies have explored the use of Outcome Mapping within the context of education. …


Spartan Daily, February 1, 2022, San Jose State University, School Of Journalism And Mass Communications Feb 2022

Spartan Daily, February 1, 2022, San Jose State University, School Of Journalism And Mass Communications

Spartan Daily, 2022

Volume 158, Issue 2


The Learning Log, February 2022, Lindenwood University Feb 2022

The Learning Log, February 2022, Lindenwood University

Learning Log

The Learning Log is the electronic newsletter of the Lindenwood University Learning Academy.


Premier: The Magazine Of The Unlv Harrah College Of Hospitality, Matt Jacob, Angela Ramsey, Caitlyn Lopez, Stowe Shoemaker, Maggie Hausbeck, Alexandra Liebman Feb 2022

Premier: The Magazine Of The Unlv Harrah College Of Hospitality, Matt Jacob, Angela Ramsey, Caitlyn Lopez, Stowe Shoemaker, Maggie Hausbeck, Alexandra Liebman

Premier: The Magazine of the UNLV Harrah Hotel College

Of the countless hospitality programs around the world, why does the Harrah College of Hospitality consistently rank at the top? I believe the college's excellence stems from our ability to leverage our strengths with those of our partners to do great things. It's that simple.

This approach has certainly been in play as we've navigated the difficulties of the past two years. We've worked with our friends in industry and academia to bolster our internship and mentorship programs, research, and interdisciplinary projects, all with the intent of expanding the knowledge base of the hospitality discipline and building a pipeline of …


Extensive Identification Of Genes Involved In Congenital And Structural Heart Disorders And Cardiomyopathy., Nadine Spielmann, Gregor Miller, Tudor I Oprea, Chih-Wei Hsu, Gisela Fobo, Goar Frishman, Corinna Montrone, Hamed Haseli Mashhadi, Jeremy Mason, Violeta Munoz Fuentes, Stefanie Leuchtenberger, Andreas Ruepp, Matias Wagner, Dominik S Westphal, Cordula Wolf, Agnes Görlach, Adrián Sanz-Moreno, Yi-Li Cho, Raffaele Teperino, Stefan Brandmaier, Sapna Sharma, Isabella Rikarda Galter, Manuela A Östereicher, Lilly Zapf, Philipp Mayer-Kuckuk, Jan Rozman, Lydia Teboul, Rosie K A Bunton-Stasyshyn, Heather Cater, Michelle Stewart, Skevoulla Christou, Henrik Westerberg, Amelia M Willett, Janine M Wotton, Willson B Roper, Audrey E Christiansen, Christopher S Ward, Jason D Heaney, Corey L Reynolds, Jan Prochazka, Lynette Bower, David Clary, Mohammed Selloum, Ghina Bou About, Olivia Wendling, Hugues Jacobs, Sophie Leblanc, Hamid Meziane, Tania Sorg, Enrique Audain, Arthur Gilly, Nigel W Rayner, Impc Consortium, Genomics England Research Consortium, Marc-Phillip Hitz, Eleftheria Zeggini, Eckhard Wolf, Radislav Sedlacek, Stephen A Murray, Karen L. Svenson, Robert E Braun, Jacqueline K White, Lois Kelsey, Xiang Gao, Toshihiko Shiroishi, Ying Xu, Je Kyung Seong, Fabio Mammano, Glauco P Tocchini-Valentini, Arthur L Beaudet, Terrence F Meehan, Helen Parkinson, Damian Smedley, Ann-Marie Mallon, Sara E Wells, Harald Grallert, Wolfgang Wurst, Susan Marschall, Helmut Fuchs, Steve D M Brown, Ann M Flenniken, Lauryl M J Nutter, Colin Mckerlie, Yann Herault, K C Kent Lloyd, Mary E Dickinson, Valerie Gailus-Durner, Martin Hrabe De Angelis Feb 2022

Extensive Identification Of Genes Involved In Congenital And Structural Heart Disorders And Cardiomyopathy., Nadine Spielmann, Gregor Miller, Tudor I Oprea, Chih-Wei Hsu, Gisela Fobo, Goar Frishman, Corinna Montrone, Hamed Haseli Mashhadi, Jeremy Mason, Violeta Munoz Fuentes, Stefanie Leuchtenberger, Andreas Ruepp, Matias Wagner, Dominik S Westphal, Cordula Wolf, Agnes Görlach, Adrián Sanz-Moreno, Yi-Li Cho, Raffaele Teperino, Stefan Brandmaier, Sapna Sharma, Isabella Rikarda Galter, Manuela A Östereicher, Lilly Zapf, Philipp Mayer-Kuckuk, Jan Rozman, Lydia Teboul, Rosie K A Bunton-Stasyshyn, Heather Cater, Michelle Stewart, Skevoulla Christou, Henrik Westerberg, Amelia M Willett, Janine M Wotton, Willson B Roper, Audrey E Christiansen, Christopher S Ward, Jason D Heaney, Corey L Reynolds, Jan Prochazka, Lynette Bower, David Clary, Mohammed Selloum, Ghina Bou About, Olivia Wendling, Hugues Jacobs, Sophie Leblanc, Hamid Meziane, Tania Sorg, Enrique Audain, Arthur Gilly, Nigel W Rayner, Impc Consortium, Genomics England Research Consortium, Marc-Phillip Hitz, Eleftheria Zeggini, Eckhard Wolf, Radislav Sedlacek, Stephen A Murray, Karen L. Svenson, Robert E Braun, Jacqueline K White, Lois Kelsey, Xiang Gao, Toshihiko Shiroishi, Ying Xu, Je Kyung Seong, Fabio Mammano, Glauco P Tocchini-Valentini, Arthur L Beaudet, Terrence F Meehan, Helen Parkinson, Damian Smedley, Ann-Marie Mallon, Sara E Wells, Harald Grallert, Wolfgang Wurst, Susan Marschall, Helmut Fuchs, Steve D M Brown, Ann M Flenniken, Lauryl M J Nutter, Colin Mckerlie, Yann Herault, K C Kent Lloyd, Mary E Dickinson, Valerie Gailus-Durner, Martin Hrabe De Angelis

Faculty Research 2022

Clinical presentation of congenital heart disease is heterogeneous, making identification of the disease-causing genes and their genetic pathways and mechanisms of action challenging. By using in vivo electrocardiography, transthoracic echocardiography and microcomputed tomography imaging to screen 3,894 single-gene-null mouse lines for structural and functional cardiac abnormalities, here we identify 705 lines with cardiac arrhythmia, myocardial hypertrophy and/or ventricular dilation. Among these 705 genes, 486 have not been previously associated with cardiac dysfunction in humans, and some of them represent variants of unknown relevance (VUR). Mice with mutations in Casz1, Dnajc18, Pde4dip, Rnf38 or Tmem161b genes show developmental cardiac structural abnormalities, …


School-Level Perspectives Of The Ontario School Nutrition Program, Mariam R. Ismail, Jason A. Gilliland, June I. Matthews, Danielle S. Battram Feb 2022

School-Level Perspectives Of The Ontario School Nutrition Program, Mariam R. Ismail, Jason A. Gilliland, June I. Matthews, Danielle S. Battram

Paediatrics Publications

The purpose of this study was to assess the implementation of a school snack program for children in elementary schools. School-level program volunteers’ experiences were explored using semi-structured interviews. Fieldnotes were taken during on-site school visits. Quantitative data were collected through a General Information Form and Weekly Logbooks. Seven elementary schools in Southwestern Ontario were invited and agreed to participate. Interviews (n = 27) revealed that volunteers valued the program for its universality, the excitement it created, the opportunity for students to try new foods, and the social interactions that it generated. Challenges included the burden on snack volunteers to …


Be Healthy In Pregnancy (Bhip): A Randomized Controlled Trial Of Nutrition And Exercise Intervention From Early Pregnancy To Achieve Recommended Gestational Weight Gain, Stephanie A. Atkinson, Atherai Maran, Kendra Dempsey, Maude Perreault, Thuva Vanniyasingam, Stuart M. Phillips, Eileen K. Hutton, Michelle F. Mottola Feb 2022

Be Healthy In Pregnancy (Bhip): A Randomized Controlled Trial Of Nutrition And Exercise Intervention From Early Pregnancy To Achieve Recommended Gestational Weight Gain, Stephanie A. Atkinson, Atherai Maran, Kendra Dempsey, Maude Perreault, Thuva Vanniyasingam, Stuart M. Phillips, Eileen K. Hutton, Michelle F. Mottola

Paediatrics Publications

A randomized two-arm prospective superiority trial tested the efficacy of a novel structured and monitored nutrition (bi-weekly counselling for individualized energy and high dairy protein diet) and exercise program (walking goal of 10,000 steps/day) (intervention) compared to usual care (control) in pregnant women to achieve gestational weight gain (GWG) within current recommendations. Women recruited in communities in southern Ontario, Canada were randomized at 12–17 weeks gestation with stratification by site and pre-pregnancy BMI to intervention (n = 119) or control (n = 122). The primary outcome was the proportion of women who achieved GWG within the Institute of Medicine recommendations. …


Body Mass Index (Bmi): A Screening Tool Analysis, Deepesh Khanna, Cadynce Peltzer, Payal Kahar, Mayur S. Parmar Feb 2022

Body Mass Index (Bmi): A Screening Tool Analysis, Deepesh Khanna, Cadynce Peltzer, Payal Kahar, Mayur S. Parmar

HPD Articles

Body mass index (BMI), a measurement based on a person's height and weight, allows the classification of individuals into categories such as obese or overweight. With these classifications, we can assess risk for hypertension, diabetes, cancer, hypercholesterolemia, and other chronic diseases. Furthermore, childhood BMI serves as a prediction method for health and disease later in life. Along with BMI, researchers also study waist circumference and waist-to-hip ratio in correlation with the above-mentioned chronic illnesses. This brief review explores the associations between body mass index, waist circumference, and the waist-hip ratio as measurements and their capability as predictors for persistent conditions …


Status Of Vitamin D In Children With Pediatric Acute-Onset Neuropsychiatric Syndrome (Pans), Gabriel Delgado '22 Feb 2022

Status Of Vitamin D In Children With Pediatric Acute-Onset Neuropsychiatric Syndrome (Pans), Gabriel Delgado '22

Student Publications & Research

Numerous studies have indicated an association between vitamin D deficiency and the immune dysregulation and the pathogenesis of autoimmunity. An increased prevalence of vitamin D deficiency has been demonstrated in several pediatric autoimmune diseases, including autoimmune thyroid disease and Type-1 diabetes mellitus. This study was undertaken to determine the prevalence of vitamin D deficiency in children with PANS, an autoimmune disorder characterized by abrupt-onset neuropsychiatric symptoms.