Digital Commons Network^™

Temporal Trends Of Persistent Organic Pollutants In Sarasota Bay Common Bottlenose Dolphins (Tursiops Truncatus), John Kucklick, Ashley Boggs, Kevin Huncik, Amanda Moors, Elizabeth Davis, Gina Ylitalo, Mary Mcconnell, Christina Makris, Randall S. Wells

Scholarship and Professional Work – COPHS

No abstract provided.

Ms 041 Guide To Maurice J. Meynier, Md Papers (1904-1989), Maurice J. Meynier Jr

Manuscript Finding Aids

The Maurice J. Meynier, MD papers contains information about Dr. Meynier childhood, education and participation in World War II. Material includes correspondence, reprints, some handwritten manuscripts, certificates and diplomas, newspaper and magazine articles, brochures, glass slides, photographs and photographic slides. See more at MS 041.

2022-February-17-Five Years Of Caring For Patients With Als, University Marketing And Communication, East Tennessee State University

ETSU News

A Patient's Perspective

“The clinic has been my lifeline in knowing what to do to help ease the difficulties of this disease.”

Jean Peace, pictured at left with her daughter, Jennifer Humphrey

JOHNSON CITY, Tenn. (Feb. 17, 2022) – Before she was diagnosed with ALS, or amyotrophic lateral sclerosis, in March 2021, Jean Peace played tennis four days a week and enjoyed an active lifestyle that included power walking, kayaking and paddle boarding.

After her diagnosis, Peace, who lives in Kingsport, had to learn to navigate a new lifestyle – one that will soon include a motorized wheelchair and a …

Role Of Specialized Pro-Resolving Mediators In Reducing Neuroinflammation In Neurodegenerative Disorders, Jana Ponce, Arzu Ulu, Corrine Hanson, Erin Cameron-Smith, Jenna Wuebker, John Bertoni, Alfred Fisher, Ka-Chun Siu, Vivien Marmelat, Jiri Adamec, Danish Bhatti

Department of Biochemistry: Faculty Publications

Alzheimer’s disease (AD) and Parkinson’s disease (PD) are neurodegenerative disorders that affect millions of individuals worldwide. As incidence of these conditions increases with age, there will undoubtedly be an increased prevalence of cases in the near future. Neuroinflammation is a hallmark in the development and progression of neurodegenerative diseases and prevention or resolution of chronic neuroinflammation may represent a novel approach to treatment. The present review highlights the potential of the anti-inflammatory and pro-resolving effects of polyunsaturated fatty acid (PUFA)- derived mediators (Specialized Pro-resolving Mediators—SPM) in neurodegenerative disorders. PUFA-derived SPM are biosynthesized in response to chemicals produced from acute inflammatory …

The Weekly Challenger, February 17, 2022, The Weekly Challenger, Et Al

Weekly Challenger Newspaper Collection

The February 17, 2022, issue of The Weekly Challenger.

Gc Minutes Feb 17, 2022, Graduate Council

Graduate Council Minutes

No abstract provided.

Assessing Infant Cognition In Field Settings Using Eye-Tracking: A Pilot Cohort Trial In Sierra Leone, Jukka Leppänen, Julius Butcher, Claire Godbout, Kevin Stephenson, D. Taylor Hendrixson, Stacy Griswold, Beatrice Rogers, Patrick Webb, Aminata Koroma, Mark Manary

Open Access Publications

OBJECTIVES: To investigate the feasibility of eye-tracking-based testing of the speed of visual orienting in malnourished young children at rural clinics in Sierra Leone.

DESIGN: Prospective dual cohort study nested in a cluster-randomised trial.

SETTING: 8 sites participating in a cluster-randomised trial of supplementary feeding for moderate acute malnutrition (MAM).

PARTICIPANTS: For the MAM cohort, all infants aged 7-11 months at the eight sites were enrolled, 138 altogether. For controls, a convenience sample of all non-malnourished infants aged 7-11 months at the same sites were eligible, 60 altogether. A sample of 30 adults at the sites also underwent eye-tracking tests …

Repair-Assisted Damage Detection Reveals Biological Disparities In Prostate Cancer Between African Americans And European Americans, Kimiko L Krieger, Jie H Gohlke, Kevin J Lee, Danthasinghe Waduge Badrajee Piyarathna, Patricia D Castro, Jeffrey A Jones, Michael M Ittmann, Natalie R Gassman, Arun Sreekumar

Faculty, Staff and Students Publications

African Americans (AA) are two times more likely to be diagnosed with and succumb to prostate cancer (PCa) compared to European Americans (EA). There is mounting evidence that biological differences in these tumors contribute to disparities in patient outcomes. Our goal was to examine the differences in DNA damage in AA and EA prostate tissues. Tissue microarrays with matched tumor-benign adjacent pairs from 77 AA and EA PCa patients were analyzed for abasic sites, oxidative lesions, crosslinks, and uracil content using the Repair Assisted Damage Detection (RADD) assay. Our analysis revealed that AA PCa, overall, have more DNA damage than …

Novel Role Of Ghrelin Receptor In Gut Dysbiosis And Experimental Colitis In Aging, Ji Yeon Noh, Chia-Shan Wu, Jennifer A A Deluca, Sridevi Devaraj, Arul Jayaraman, Robert C Alaniz, Xiao-Di Tan, Clinton D Allred, Yuxiang Sun

Faculty, Staff and Students Publications

Chronic low-grade inflammation is a hallmark of aging, which is now coined as inflamm-aging. Inflamm-aging contributes to many age-associated diseases such as obesity, type 2 diabetes, cardiovascular disease, and inflammatory bowel disease (IBD). We have shown that gut hormone ghrelin, via its receptor growth hormone secretagogue receptor (GHS-R), regulates energy metabolism and inflammation in aging. Emerging evidence suggests that gut microbiome has a critical role in intestinal immunity of the host. To determine whether microbiome is an integral driving force of GHS-R mediated immune-metabolic homeostasis in aging, we assessed the gut microbiome profiles of young and old GHS-R global knockout …

Benefits Of Chinese Qigong Mind-Body Exercise Program On Salivary Biomarkers And Physical Functions In Older Adults, Salmaan Faghihi, Ashley Nguyen, Karen Cruz, Mary Bahwawsi, Joseph Nocito, Zenong Yin, Yan Du, Tianou Zhang

International Journal of Exercise Science: Conference Proceedings

Chinese Qigong mind-body exercise such as Five Animal Frolics have been shown to improve quality of life, physical functions, cognitive functions, and mental health in older adults with various chronic health conditions. However, there is a lack of comprehensive understanding of the biological mechanisms, underlying the health effects after exposing to conventional and mind-body exercise. PURPOSE: The purpose of the study is to profile the changes associated with salivary biomarkers and physical functions after exposure to a 12-week five animal frolics, Chinese Qigong mind-body exercise program in community-dwelling older adults. METHODS: Thirteen community-dwelling adults who attended the Senior …

Males, But Not Females, Demonstrate Mitochondrial Dysfunction In The C26 Model Of Cancer Cachexia, Ricky D. Solis, J. William Deaver, Eleanor R. Schrems, Ana Regina Cabrera, Seongkyun Lim, Francielle Morena Da Silva, Tyrone A. Washington, Nicholas P. Greene, Michael P. Wiggs

International Journal of Exercise Science: Conference Proceedings

Cancer cachexia is characterized by progressive muscle wasting that can lead to symptoms such as anemia, severe weight loss, and fatigue. These symptoms can lead to limitations in activities of daily living and can cause resistance to chemotherapy treatments in cancer patients. There are no current treatments available to treat cancer cachexia and a critical need remains to identify mechanisms of cancer cachexia. Recently, our group identified mitochondrial disfunction precedes muscle atrophy in males but not females in a model of lung cancer induced atrophy. However, it is unknown whether this finding is replicated when studying a different type of …

Training Modifications In Endurance Athletes Due To Covid-19 Restrictions, Birinder Nijjar, Meena Shah, Kamiah Moss, Andreas Kreutzer, Austin J. Graybeal, Robyn Braun-Trocchio, Yan Zhang, Ryan R. Porter

International Journal of Exercise Science: Conference Proceedings

The COVID-19 pandemic created a situation that abruptly altered the life of nearly every individual, forcing them to adjust their daily habits. Adults who regularly engaged in daily physical activity, either as recreational, collegiate, or professional athletes prior to lockdowns had to subsequently adapt and change their training regimens. PURPOSE: To determine which characteristics (age, sex, education level, socioeconomic status, primary endurance sport, whether the athlete is being coached or following a training program, and prior competition medaling) of recreational, collegiate, and professional endurance athletes were associated with training changes due to COVID-19 safety restrictions. METHODS: A cross-sectional …

Novel Energy Drink Improves Mood And Raises Blood Pressure, But Has No Effect On Cardiac Qtc Interval Or Rate-Pressure Product In Young Adult Gamers, Nathaniel Helwig, Laura Schwager, Emily Rogers, Nile Banks, Chris Lockwood, Nathaniel D.M. Jenkins

International Journal of Exercise Science: Conference Proceedings

Novel energy drink formulations have been introduced to the market that are purported to have nootropic effects – including improving mood. Despite their rapidly growing popularity, especially among video gamers, there is minimal evidence supporting their efficacy or establishing their cardiovascular safety profiles. PURPOSE: We conducted a randomized, double-blind, placebo-controlled, crossover trial to investigate the effects of acute consumption of a non-caloric, novel energy drink (NED) containing 200 mg caffeine, citicoline, tyrosine, B-vitamins, and carboxylic acids on mood and cardiovascular safety outcomes. We hypothesized that NED would improve mood without significant adverse cardiovascular effects when compared to placebo. METHODS: Forty-five …

Using Hba1c To Diagnose Diabetes In The Uc, Davis-Type 2 Diabetes Mellitus Rat Model, Yu Henry Huo, Jennice Herrera, Kimber L. Stanhope, James L. Graham, Peter J. Havel D.V.M., Ph.D., Audrey J. Stone, Michelle L. Harrison

International Journal of Exercise Science: Conference Proceedings

With disease progression, type 2 diabetes mellitus (T2DM) leads to debilitating complications arising from damage to nerves and blood vessels. Importantly, investigations focusing on T2DM progression have the capacity to distinguish individuals at greater risk for these severe complications through the identification of predictive biomarkers. Hence, the accurate diagnosis of T2DM is critical to such investigations. UC Davis (UCD) T2DM rats are born without diabetes and develop the disease over time with a similar pathophysiology to that in humans. This unique rat model allows researchers to investigate predictive biomarkers linked to the progression of T2D; however, such investigations require an …

Effects Of 8-Week Ketogenic Diet On Anthropometrics, Body Composition, Metabolic Parameters, And Psychological Factors In Young Obese Population, Hayden G. West, Soon-Mi Choi, Frank B. Wyatt, Michael W. Olson

International Journal of Exercise Science: Conference Proceedings

Obese have a significantly higher Body Mass Index (BMI), which can be associated with poor nutritional intake and sedentary lifestyles. The ketogenic diet is a form of a dietary intervention which is often implemented for metabolic syndrome individuals such as obese populations. PURPOSE: The purpose of this study was to measure the effects of a ketogenic diet on anthropometrics, body composition, metabolic parameters, and psychological factors in young obese population. METHODS: Seven young obese participants (n=7, height (cm); 174.8 ± 10.9, weight (kg); 105 ± 20.7, BMI (kg∙m^-2); 34.6 ± 4.8) completed an 8-week intervention with …

Associations With The Number Of Well-Known Grocery Stores, Gyms, And Parks To Median Household Income, Sara Le, Edward Merritt Phd, Vanessa Mikan Phd

International Journal of Exercise Science: Conference Proceedings

Segregated neighborhoods are linked to the environmental exposures, education and behavior of their residents. Access to exercise and nutrition resources are dependent on whether or not residents are able to afford it or not. PURPOSE: To identify the associations between the location of nutrition and exercise resources to household income. METHODS: Selective Zip codes in the Austin Area were used to identify the median household income through an online search where data is collected from the U.S. Census. Selective grocery store companies and gyms were found through an online search of their website “store locator.” Neighborhood parks were identified by …

Impact Of Menstrual Phases On Stress Markers: A Pilot Study, Bailey C. Weishaar, Hunter S. Waldman, Kyle T. Patek, Matthew J. Mcallister

International Journal of Exercise Science: Conference Proceedings

PURPOSE: Previous research has shown that different phases of the menstrual cycle may impact biometrics such as markers of stress and inflammation [e.g., cortisol (CORT), interleukin-6] as well as body composition. However, there is scarce literature regarding markers of stress and oxidative stress such as salivary a-amylase (sAA), immunoglobin-A (SIgA) and uric acid (UA), in relation to the four different menstrual phases. The purpose of this study was to examine the impact of menstrual phases on sAA, CORT, UA and SIgA. METHODS: 21 pre-menopausal women with regular menstrual cycles (n=9) oral contraceptive users (OC) and ( …

Measurement Of Respiratory Exchange Ratio (Rer) With Oral Versus Oronasal Breathing After Sports Drink Mouth Rinse, Meeshti Shethia, Edward Merritt

International Journal of Exercise Science: Conference Proceedings

The ratio of carbon dioxide produced to oxygen consumed, the respiratory exchange ratio (RER), is often used to determine the balance of carbohydrate and fat oxidation during exercise. However, introducing carbohydrates into the mouth and pharynx could possibly influence the value while not actually changing the whole-body metabolism. PURPOSE: The purpose of this study was to determine if a sports drink mouth rinse during steady-state (SS) exercise affects RER. METHODS: Eleven participants exercised at steady state in 4 different, randomized conditions while respiratory gases were analyzed: 1) Breathing through the mouth after water rinse; 2), breathing through the mouth …

Kinetic Chain Rehabilitation In A Juvenile Idiopathic Arthritis Patient, Melissa D. Long, Erin D. Dorrel

International Journal of Exercise Science: Conference Proceedings

CASE HISTORY: The patient’s chief complaint was decreasing ROM and pain noticed after conservative orthopedic treatment in the dominant (left) elbow. After extensive evaluation, the patient was diagnosed with juvenile idiopathic arthritis (JIA) at 9 years old. PHYSICAL EXAM: Upon physical therapist examination, it was determined that she had deficits throughout the entire left upper extremity and quadrant. Findings include signs and symptoms of Upper Cross Syndrome including pectoralis muscle group tightness, weakness of deep neck flexors with overuse of sternocleidomastoid and scalenes group, weakness of posterior shoulder and upper back including lower trap, middle trap, and all …

Geranylgeraniol Supplementation Mitigates Muscle Atrophy With Mitochondrial Quality Improvement In Diabetic Rats, Nigel C. Jiwan, Casey Appell, Rui Wang, Chwan-Li Shen, Hui-Ying Luk

International Journal of Exercise Science: Conference Proceedings

With diabetes, skeletal muscle mitochondrial quality control (mitochondrial fusion, fission & macro-autophagy) is impaired. Geranylgeraniol (GG) is shown to have a protective effect on preventing mitochondrial damage and muscle health; however, the effect of GG on a diabetic model is not known. PURPOSE: To determine the effect of GG on mitochondrial quality control and muscle cross-sectional area (CSA) in diabetic rats. METHODS: Thirty-five Sprague-Dawley rats were divided into three diet groups: control diet (CON), high-fat diet with 35 mg/kg body weight of streptozotocin (HFD), and HFD with 800 mg/kg body weight of GG (GG). Due to the limited sample, a …

Special Olympics Fitness Assessment Project, Vanessa G. Garza, Victoria I. Moreno

International Journal of Exercise Science: Conference Proceedings

Fitness is an important aspect of the Special Olympics mission. Physical activity, adequate nutrition, and hydration enhance athletes’ sports performance and improve health and overall quality of life. PURPOSE: The purpose of the study is under a service contract, assist Special Olympics International in data collection to evaluate the effectiveness of their Fit 5 program intervention. Analyze the health and fitness status of the Rio Grande Valley Special Olympics Athletes and the effectiveness of the Fit 5 program in the area. METHODS: Participant eligibility were current special Olympic athletes aged 18 and older in the Rio Grande Valley area. Forty-six …

Effect Of Single Vs Accumulated Bouts Of Exercise On Body Composition, Fitness, And Resting Metabolic Rate, Katherine Jankevicius, Alex Alvara, James Rowe

International Journal of Exercise Science: Conference Proceedings

PURPOSE: To examine how the effects of accumulated exercise compare to continuous exercise on body composition, VO₂max, and metabolic rate. METHODS: Mildly active males (n = 4) and females (n = 5) were randomly selected to perform either 1) continuous exercise consisting of one 30-minute bout of Tabata (1-bout), 2) accumulated exercise consisting of two 15-minute bouts of Tabata (2-bout), or 3) no exercise (control). Both exercise groups performed Tabata three times per week for 4 weeks. Each group had three participants (2 males and 1 female) with the exception of the 2-bout group which had 3 …

The Effects Of Body Composition On Resting Metabolic Rate Among College Aged Students, Natalie A. Delgadillo, Frank Wyatt, Michael W. Olson, Soon-Mi Choi

International Journal of Exercise Science: Conference Proceedings

Resting metabolic rate (RMR) is the measure of daily energy expenditure while the body is at rest. RMR is becoming more useful in order to measure the energy demands in both athletes and non-athletes. PURPOSE: The purpose of this study is to analyze the RMR among college aged students, along with their body compositions in order to determine if there is a correlation between body fat percentage and RMR. METHODS: Participants in this study included 19 students at Midwestern State University between the ages of 19-25. (n = 19; female = 12; male = 7). Participants were asked prior …

Comparison Of Actual Versus Recommended Intake Of Collegiate Athletes Across Gender And Season At A Small Division I University, Benjamin C. Garza, Terah Ege, Sofia Ramos, Brittanie L. Lockard

International Journal of Exercise Science: Conference Proceedings

Collegiate athletes often struggle to consume foods that provide adequate energy and nutrition to fuel their demanding physical performance and recovery needs. The increased energy expenditure during in- versus off-season training may further hinder an athlete’s ability to meet recommended intake guidelines. PURPOSE: to assess Division I student-athlete nutrition intake (calories, protein, carbohydrates, and fat) throughout training seasons of the 2019-2021 school years. METHODS: From 2019-2021, 29 athletes (male: n=9, Wt=76.9 ± 2.2kg, LBM=66.0 ± 6.7kg; female: n=20, Wt=68.6 ± 3.7, LBM=51.4 ± 1.7kg) completed 3-day intake (ASA24) logs monthly. Body composition (InBody 570, BIA) and sport nutrition …

Case Presentation For Complex Regional Pain Syndrome, Corali V. Medico, Vered Arbel, Terry Nicola, Tal Amasay

International Journal of Exercise Science: Conference Proceedings

CASE HISTORY: The patient is a 54-year-old female who presented to the orthopedic clinic to evaluate a sharp burning pain in her left lower leg. She stated that the pain started eight months after an Open Reduction and Internal Fixation (ORIF) surgery of her left tibial plateau and had progressively gotten worse. She was prescribed gabapentin and oxycodone for pain and experienced minimal relief with gabapentin. Additionally, she applied analgesic gel which seems to have the most help along with the narcotic. She stated that stabbing and shooting pain radiated from her left lateral proximal tibia down to her …

Case Presentation For Axillary Nerve Injury, Anthony Williams, Vered Arbel, Terry Nicola, Tal Amasay

International Journal of Exercise Science: Conference Proceedings

CASE HISTORY: The patient is a 21-year-old male experiencing upper extremity numbness and tingling in the right deltoid. He began to experience these symptoms after a football injury and was seen by a doctor who referred him to a sports medicine specialist one month after the injury. The injury occurred during a football game, where he was struck by an opponent on the right inferior axillary region. The patient lost mobility of his right arm immediately following his injury, however, regain minimal mobility a week later. Right arm was checked for dislocation or any fractures, and none were found. …

Does Having A Glucose Peak Time Within 30 Minutes Of Glucose Ingestion Indicate Better Metabolic Flexibility?, Joshua Labadah, Ali Mossayebi, Jehu Apaflo, Victoria Rocha, Sudip Bajpeyi

International Journal of Exercise Science: Conference Proceedings

Metabolic flexibility is the ability of the body to physiologically adapt to fuel oxidation in response to fuel availability assessed by change in respiratory quotient (DRQ) from fasted to glucose/insulin-stimulated states. Glucose peak time describes the time of the highest plasma glucose concentration during an oral glucose tolerance test (OGTT). Peak time >30 minutes has been associated with increased odds of prediabetes compared to peak times ≤30 minutes. PURPOSE: The purpose of the study was to determine if glucose peak time withing 30 minutes of glucose ingestion during an OGTT is indicative of better substrate utilization. METHODS: Sixty-two …

Gender Difference In The Relationship Of Fatigue Index, Anaerobic Power And Capacity To Body Composition And Bone Mineral Status In Non-Athletes, Ali Mossayebi, Jehu N. Apaflo, Joshua Labadah, Victoria Rocha, Sudip Bajpeyi

International Journal of Exercise Science: Conference Proceedings

The fatigue index is considered an important indicator of anaerobic fitness. The lower the fatigue index, the greater the ability of the body to maintain its power output through an anaerobic performance. The Wingate test is widely used by coaches, athletes, and researchers to measure lower body power, anaerobic capacity, and fatigue index. Body composition is considered an important component of anaerobic fitness, it is not clear how gender may influence the relationship between body composition and anaerobic fitness. PURPOSE: The purpose of this study was to understand how gender may impact the relationship between body composition and anaerobic …

Biphasic Glucose Curve Morphology Reflects Better Glucose Tolerance And Substrate Utilization, Jehu Narh Apaflo, Joshua Labadah, Ali Mossayebi, Victoria Rocha, Sudip Bajpeyi

International Journal of Exercise Science: Conference Proceedings

The shape of glucose curve during an oral glucose tolerance test is a plausible risk factor for insulin resistance and other metabolic disorders and could be a potential biomarker for predicting risk for developing diabetes. PURPOSE: This study aimed to compare the glucose tolerance and substrate utilization between monophasic and biphasic glucose curve morphologies. METHODS: A total of 50 subjects (33/17 male/female; Age: 27 ± 7.74 years; BMI: 27.7 ± 4.97 kg/m²) without diabetes were tested for a two-hour oral glucose tolerance after ingesting 75g of glucose drink. Blood glucose levels were measured at time points …

Lifestyle Factors Affecting Android Fat In Hispanic Residents Of The Rgv, Alexandro Rodriguez, Ryan D. Russell, Smaran Marupudi, Gabriel Figueroa, Jaime Rodriguez, Saraswathy Nair, Jimmy Gonzalez, Yu Lun Tai

International Journal of Exercise Science: Conference Proceedings

ABSTRACT

Approximately 79% of the Hispanic population in the Rio Grande Valley (HPRGV) are overweight or obese. As such, this population also have ~3x the type 2 diabetes (T2D) rates than the US average. Distribution of adipose tissue, affected largely by genetics and lifestyle (diet and physical activity, has been identified as a key-marker for T2D risk among apparently healthy individuals. However, the relationship of lifestyle factors such as diet and physical activity on android fat in healthy young Hispanics of the RGV has not been completely explored. Purpose: The purpose of this study was to determine whether there is …