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Predictors Of Hyperkalemia And Outcomes Of Dyskalemia In Us Veterans With Advanced Chronic Kidney Disease Transitioning To Dialysis, Ankur Dashputre Apr 2022

Predictors Of Hyperkalemia And Outcomes Of Dyskalemia In Us Veterans With Advanced Chronic Kidney Disease Transitioning To Dialysis, Ankur Dashputre

Theses and Dissertations (ETD)

Background: The kidneys play a crucial role in maintaining homeostasis of serum potassium levels (K+). Patients with advanced chronic kidney disease (CKD) are at a higher risk of experiencing dyskalemia events (i.e. hyper- and hypokalemia; especially the former) and thus future adverse outcomes. Currently, there is a dearth of literature on prediction models for hyperkalemia and the effects of dyskalemia on outcomes such as incidence of ischemic stroke and short-term hospital/emergency room (ER) utilization in an advanced CKD population transitioning to dialysis. Objectives: Using a nationally representative sample of US veterans with advanced CKD transitioning to dialysis, in the pre-dialysis …


The Relationship Of Child Health And Parenting Stress To Child Neurocognitive Development, Nancy Alise Farrell Apr 2022

The Relationship Of Child Health And Parenting Stress To Child Neurocognitive Development, Nancy Alise Farrell

Theses and Dissertations (ETD)

Problem. Although the United States rates high in economic resources, the neurocognitive development (NCD) of children falls behind many other developed nations. Levels of parenting stress may be linked to sociodemographic factors such as the high incidence of poverty in children or health disparities in children, which in turn may affect NCD in children. Using the data from an observational, longitudinal cohort study of a diverse population could provide information related to parenting stress, child health, and related factors to guide and support interventions with families and policies to improve child NCD. Aims. The overall aim of this study was …


The Status Of The Nebraska Healthcare Workforce: Update 2022, Hyo Jung Tak, Nicole Carritt, Marlene Deras, Bedant Chakraborty, David Palm, Ronnie D. Horner Apr 2022

The Status Of The Nebraska Healthcare Workforce: Update 2022, Hyo Jung Tak, Nicole Carritt, Marlene Deras, Bedant Chakraborty, David Palm, Ronnie D. Horner

Reports: Rural Health

Ensuring access to health care in rural communities has been a long-standing challenge for state and federal policymakers, including within Nebraska.

To inform initiatives and policies to address these challenges, timely and accurate data on the health care workforce in the state are needed. The rapidly changing health care system has resulted in substantial changes in state and federal health policies, economic growth, demographics, population health, and many other factors that have likely impacted the evolution and distribution of the health care workforce across Nebraska. Therefore, the report, commissioned by the Nebraska Area Health Education Center (AHEC) Program in collaboration …


Nutrient And Organic Carbon Losses By Erosion, And Their Economic And Environmental Implications In The Drylands Of Kenya, Nathan O. Oduor, Monicah Mucheru-Muna, Jayne N. Mugwe, Isaya Sijali, George Nyabuga, Daniel N. Mugendi Apr 2022

Nutrient And Organic Carbon Losses By Erosion, And Their Economic And Environmental Implications In The Drylands Of Kenya, Nathan O. Oduor, Monicah Mucheru-Muna, Jayne N. Mugwe, Isaya Sijali, George Nyabuga, Daniel N. Mugendi

Graduate School of Media and Communications

Erosion causes soil nutrients and financial losses, and negatively impacts the environment. We sought to assess the effects of integrated soil fertility and soil & water management practices on nutrient losses, their equivalent economic losses, and environmental disturbance in the drylands of Tharaka-Nithi County. An experiment was set in a randomized complete block design with four replications. Six treatments implemented included manure + fertilizer + tied ridging under 120 kg ha−1 and 30 kg ha−1 nitrogen (N) application rate, manure + fertilizer + minimum tillage with crop residue mulch under 120 N kg ha−1 and 30 N kg ha−1, Managing …


Nutritional Status And Its Determinants In The Eastern Mediterranean Region. A Review, Emad A. Al-Shameri, Ahmed H. Al-Shahethi, Sharifah W. Wafa Apr 2022

Nutritional Status And Its Determinants In The Eastern Mediterranean Region. A Review, Emad A. Al-Shameri, Ahmed H. Al-Shahethi, Sharifah W. Wafa

Saudi Medical Journal

Objectives: To review relevant literature on the determinants of the nutritional status of the children below 5 years of age in the Eastern Mediterranean Regional (EMR) countries and investigate the updates related to risk factors associated with malnutrition. Methods: A search of pertinent literature and databases was conducted using the PubMed and Google Scholar databases by applying some keywords. Results: From the available literature reviewed, the mean prevalence of underweight, wasting, and stunting of the children below 5 years of age in the EMR were 12.8% (6.4%-22.6%), 7.5% (5.9%-9.4%), and 24.2% (15.6%-35.5%) respectively. The EMR countries like Sudan, Yemen, Libya, …


Utilizing Prams And Healthy People 2020 To Examine Black Women’S Breastfeeding Behavior In Louisiana Prior To The Onset Of The Covid-19 Pandemic, Almetra Amayá Granger Apr 2022

Utilizing Prams And Healthy People 2020 To Examine Black Women’S Breastfeeding Behavior In Louisiana Prior To The Onset Of The Covid-19 Pandemic, Almetra Amayá Granger

Electronic Theses and Dissertations

No abstract provided.


Gender-Specific Marketing Strategies Used By Sports Supplements: A Descriptive Study, Anna M. Cosgrove, Cori Lorts, Lynda B. Ransdell Apr 2022

Gender-Specific Marketing Strategies Used By Sports Supplements: A Descriptive Study, Anna M. Cosgrove, Cori Lorts, Lynda B. Ransdell

International Journal of Physical Activity and Health

While the use of sports supplements is common among athletes and active adults, the marketing strategies used by these sports supplement manufacturers remain unknown—especially relative to active and athletic women. This descriptive study aims to describe marketing strategies used, such as color choices, structure function claims, and picture choice, and analyze if there are gender-specific differences within the strategies. A total of 100 best-selling sports supplements were selected from three separate third-party websites. Food products, accessories, and kitchen appliances were excluded. Supplement main webpages and sports supplement-specific webpages were explored to determine which marketing strategies were used and if there …


Development Of The Teacher Efficacy Toward Providing Physical Activity In The Classroom Scale, Erin E. Centeio, E. Whitney G. Moore, Jeanne Barcelona, Hayley B. Mckown, Heather E. Erwin, Alex C. Garn Apr 2022

Development Of The Teacher Efficacy Toward Providing Physical Activity In The Classroom Scale, Erin E. Centeio, E. Whitney G. Moore, Jeanne Barcelona, Hayley B. Mckown, Heather E. Erwin, Alex C. Garn

International Journal of Physical Activity and Health

The overall aim for this study was to create and validate an instrument that helps researchers measure and better understand classroom teachers’ efficacy toward providing physical activity throughout the school day. The development of the Teacher Efficacy Toward Providing Physical Activity in the Classroom Scale (TETPPACS) occurred in two phases. First, in study one, after item development and face validity review, an exploratory factor analysis was conducted with pilot data (N = 320) to discover the factor structure of the TETPPACS. Second, with a follow-up sample (N = 192), a confirmatory factor analysis (CFA) was performed to confirm the factor …


The Relationship Between Sleep Quality And Menopausal Symptoms Among Postmenopausal Women In Saudi Arabia, Enas M. Abdelaziz, Nadia B. Elsharkawy, Sayeda M. Mohamed Apr 2022

The Relationship Between Sleep Quality And Menopausal Symptoms Among Postmenopausal Women In Saudi Arabia, Enas M. Abdelaziz, Nadia B. Elsharkawy, Sayeda M. Mohamed

Saudi Medical Journal

Objectives: To assess sleep quality and examine its relationship with menopausal symptoms among Saudi postmenopausal women. Methods: We carried out a cross-sectional study of 410 postmenopausal women, aged 50-60 years, visiting Prince Mutaib bin Abdulaziz Hospital, Maternity and Children Hospital, and primary health care clinics, Sakaka, Jouf, Saudi Arabia. The menopause rating scale (MRS) was used to assess menopause symptoms and severity, while the Pittsburgh sleep quality index (PSQI) was used to assess sleep quality. Results: The participants’ age was 53.04±4.15 years, their mean age at natural menopause was 49.14±3.07, and the meantime since their menopause was 6.50±3.84 years. The …


Borderplex Business Barometer, Volume 6, Number 4, Thomas M. Fullerton Jr., Steven L. Fullerton Apr 2022

Borderplex Business Barometer, Volume 6, Number 4, Thomas M. Fullerton Jr., Steven L. Fullerton

Border Region Modeling Project

No abstract provided.


Ten Simple Rules To Ruin A Collaborative Environment, Carolyn J. Lawrence-Dill, Robyn L. Allscheid, Albert Boaitey, Todd Bauman, Edward S. Buckler, Jennifer L. Clarke, Christopher Cullis, Jack Dekkers, Cassandra J. Dorius, Shawn F. Dorius, David Ertl, Matthew Homann, Guiping Hu, Mary Losch, Eric Lyons, Brenda Murdoch, Zahra Katy Navabi, Somashekhar Punnuri, Fahad Rafiq, James M. Reecy, Patrick S. Schnable, Nicole M. Scott, Moira Sheehan, Xavier Sirault, Margaret Staton, Christopher K. Tuggle, Alison Van Eenennaam, Rachael Voas Apr 2022

Ten Simple Rules To Ruin A Collaborative Environment, Carolyn J. Lawrence-Dill, Robyn L. Allscheid, Albert Boaitey, Todd Bauman, Edward S. Buckler, Jennifer L. Clarke, Christopher Cullis, Jack Dekkers, Cassandra J. Dorius, Shawn F. Dorius, David Ertl, Matthew Homann, Guiping Hu, Mary Losch, Eric Lyons, Brenda Murdoch, Zahra Katy Navabi, Somashekhar Punnuri, Fahad Rafiq, James M. Reecy, Patrick S. Schnable, Nicole M. Scott, Moira Sheehan, Xavier Sirault, Margaret Staton, Christopher K. Tuggle, Alison Van Eenennaam, Rachael Voas

Faculty Publications

Trigger warning: Here, you will find a bit of satire, written from the not-so-funny, real experiences of the authors who have been involved in “team science” collaboratives. The material presented below covers topics that readers may find offensive or even traumatizing. We present a breakdown (pun intended) of how to ruin a functioning collaboration, rather than how to build one.

The ideas contained in this work were developed during two virtual meetings of members of the Agricultural Genome to Phenome Initiative (AG2PI; www.ag2pi.org) community and leadership team in May and June of 2021. In these sessions, we looked back …


Vulnerable Vegetables And Efficient Fishers: A Study Of Primary Production Food Losses And Waste In Ireland, Tracey O'Connor, Rosanna Kleeman, Jennifer Attard Apr 2022

Vulnerable Vegetables And Efficient Fishers: A Study Of Primary Production Food Losses And Waste In Ireland, Tracey O'Connor, Rosanna Kleeman, Jennifer Attard

Publications

From 2022, the European Union Waste Framework Directive (WFD) requires member states to report annual food waste from each food supply chain stage. Comprehensive food losses and waste (FLW) data can be challenging to obtain for the primary production stage, i.e., farming and fishing. However, this information is vital in developing FLW mitigation actions appropriate to each country. This study describes the nature and extent of FLW from primary production in Ireland, using methods approved for WFD reporting. Causes of FLW and FLW as a proportion of total production were determined through interviews with Irish primary production stakeholders and using …


Metabolic Inflexibility In Youth With Obesity: Is It A Feature Of Obesity Or Distinctive Of Youth Who Are Metabolically Unhealthy?, Nour Y Gebara, Joon Young Kim, Fida Bacha, Sojung Lee, Silva Arslanian Apr 2022

Metabolic Inflexibility In Youth With Obesity: Is It A Feature Of Obesity Or Distinctive Of Youth Who Are Metabolically Unhealthy?, Nour Y Gebara, Joon Young Kim, Fida Bacha, Sojung Lee, Silva Arslanian

Faculty, Staff and Students Publications

Individuals with obesity have metabolic inflexibility with diminished fasting fat oxidation and blunted increase in respiratory quotient (RQ) in insulin-stimulated states. However, it is unclear if metabolic inflexibility is a characteristic of obesity per se or is unique to youth who have metabolically unhealthy obesity (MUO) compared with metabolically healthy obesity (MHO). We investigated metabolic flexibility in youth with MUO, MHO and normal weight (NW) and compared their metabolic characteristics. Youth (n = 188) were divided, based on cut-off points for in vivo insulin sensitivity (IS) of adolescents with NW, into 137 with MUO and 51 with MHO. Fasting hepatic …


Eco Yoga Therapy For Mental Health Related To The Covid-19 Pandemic, Karyn Stein Apr 2022

Eco Yoga Therapy For Mental Health Related To The Covid-19 Pandemic, Karyn Stein

LMU Theses and Dissertations

Recently the magnitude of the mental health crisis due to the COVID-19 pandemic has been emerging. Reports of anxiety or depression related to COVID-19 have been on the rise globally. Individuals have been living in a perpetual state of the unknown for over two years. Fear of the virus, sickness of oneself or family/friends and social isolation have taken a toll. According to the WHO, anxiety and depression have gone up 25% in the last year (2022). The effects of a rising mental health crisis will be drastic on top of the deaths and sickness related to COVID-19. While governments …


How The Farm Bill May Be The Key To Healthier Cities, Fatima Ouedraogo Apr 2022

How The Farm Bill May Be The Key To Healthier Cities, Fatima Ouedraogo

Cardozo Journal of Equal Rights & Social Justice

The note argues that the Farm Bill, a significant piece of U.S. legislation governing agricultural and food programs, can be a crucial tool in addressing urban health issues by making healthy food more affordable. By expanding subsidies to include specialty crops like fruits and vegetables, the Farm Bill could reduce the cost of these items, thereby encouraging healthier diets and combating rising obesity rates in urban populations.


Bezhigwan Ji-Izhi-Ganawaabandiyang: The Rights Of Nature And Its Jurisdictional Application For Anishinaabe Territories, Kekek Jason Stark Apr 2022

Bezhigwan Ji-Izhi-Ganawaabandiyang: The Rights Of Nature And Its Jurisdictional Application For Anishinaabe Territories, Kekek Jason Stark

Montana Law Review

No abstract provided.


Examining 24-Hour Activity And Sleep Behaviors And Related Determinants In Latino Adolescents And Young Adults With Obesity, Erica G Soltero, Neeku Navabi, Kiley B Vander Wyst, Edith Hernandez, Felipe G Castro, Stephanie L Ayers, Jenny Mendez, Gabriel Q Shaibi Apr 2022

Examining 24-Hour Activity And Sleep Behaviors And Related Determinants In Latino Adolescents And Young Adults With Obesity, Erica G Soltero, Neeku Navabi, Kiley B Vander Wyst, Edith Hernandez, Felipe G Castro, Stephanie L Ayers, Jenny Mendez, Gabriel Q Shaibi

Children’s Nutrition Research Center Staff Publications

Background.

Few studies have examined 24-hour activity and sleep behaviors and their contribution to type 2 diabetes (T2D) in Latino adolescents and young adults with obesity.

Aim.

This study included quantitative data on T2D risk and 24-hour activity and sleep behaviors and qualitative data on individual, social, and environmental behavioral determinants.

Method.

A 7 day, 24-hour, wrist-worn accelerometer protocol assessed moderate-to-vigorous physical activity (PA), sedentary behaviors (SB), sleep, and sleep regularity, in adolescents (N = 38; 12–16 years) and young adults (N = 22; 18–22 years). T2D-related outcomes included adiposity (BMI, BF%, waist circumference), fasting, and 2-hour glucose. …


Food Assistance Use Among Food Bank Clients Affected By Type 2 Diabetes, Eliza Short, Jayati Sharma, Debbe I Thompson, Douglas Taren, Rhonda Gonzalez, Melanie Hingle Apr 2022

Food Assistance Use Among Food Bank Clients Affected By Type 2 Diabetes, Eliza Short, Jayati Sharma, Debbe I Thompson, Douglas Taren, Rhonda Gonzalez, Melanie Hingle

Children’s Nutrition Research Center Staff Publications

Objective: To understand the perspectives of food bank clients affected by type 2 diabetes (T2DM).

Design: Semi-structured in-depth interviews conducted with food bank clients.

Setting: Arizona regional food bank.

Participants: Twenty English- and Spanish-speaking food bank clients with T2DM or living with a person with T2DM, aged 45-83 years, majority female, Hispanic, and food insecure.

Phenomenon of interest: Food bank use and preferences, and how these related to T2DM management.

Analysis: A hybrid thematic analysis combining inductive and deductive reasoning.

Results: Three organizing themes emerged from the analysis. First, food assistance was influenced by food preferences and the ability to …


Trans Fatty Acid Biomarkers And Incident Type 2 Diabetes: Pooled Analysis Of 12 Prospective Cohort Studies In The Fatty Acids And Outcomes Research Consortium (Force), Heidi T M Lai, Fumiaki Imamura, Andres V Ardisson Korat, Rachel A Murphy, Nathan Tintle, Julie K Bassett, Jiaying Chen, Janine Kröger, Kuo-Liong Chien, Mackenzie Senn, Alexis C Wood, Nita G Forouhi, Matthias B Schulze, William S Harris, Ramachandran S Vasan, Frank Hu, Graham G Giles, Allison Hodge, Luc Djousse, Ingeborg A Brouwer, Frank Qian, Qi Sun, Jason H Y Wu, Matti Marklund, Rozenn N Lemaitre, David S Siscovick, Amanda M Fretts, Aladdin H Shadyab, Joann E Manson, Barbara V Howard, Jennifer G Robinson, Robert B Wallace, Nick J Wareham, Yii-Der Ida Chen, Jerome I Rotter, Michael Y Tsai, Renata Micha, Dariush Mozaffarian, Fatty Acids And Outcomes Research Consortium (Force) Apr 2022

Trans Fatty Acid Biomarkers And Incident Type 2 Diabetes: Pooled Analysis Of 12 Prospective Cohort Studies In The Fatty Acids And Outcomes Research Consortium (Force), Heidi T M Lai, Fumiaki Imamura, Andres V Ardisson Korat, Rachel A Murphy, Nathan Tintle, Julie K Bassett, Jiaying Chen, Janine Kröger, Kuo-Liong Chien, Mackenzie Senn, Alexis C Wood, Nita G Forouhi, Matthias B Schulze, William S Harris, Ramachandran S Vasan, Frank Hu, Graham G Giles, Allison Hodge, Luc Djousse, Ingeborg A Brouwer, Frank Qian, Qi Sun, Jason H Y Wu, Matti Marklund, Rozenn N Lemaitre, David S Siscovick, Amanda M Fretts, Aladdin H Shadyab, Joann E Manson, Barbara V Howard, Jennifer G Robinson, Robert B Wallace, Nick J Wareham, Yii-Der Ida Chen, Jerome I Rotter, Michael Y Tsai, Renata Micha, Dariush Mozaffarian, Fatty Acids And Outcomes Research Consortium (Force)

Children’s Nutrition Research Center Staff Publications

Objective: Trans fatty acids (TFAs) have harmful biologic effects that could increase the risk of type 2 diabetes (T2D), but evidence remains uncertain. We aimed to investigate the prospective associations of TFA biomarkers and T2D by conducting an individual participant-level pooled analysis.

Research design and methods: We included data from an international consortium of 12 prospective cohorts and nested case-control studies from six nations. TFA biomarkers were measured in blood collected between 1990 and 2008 from 25,126 participants aged ≥18 years without prevalent diabetes. Each cohort conducted de novo harmonized analyses using a prespecified protocol, and findings were pooled using …


Identification Of Genetic Loci Simultaneously Associated With Multiple Cardiometabolic Traits, Alexis C Wood, Amit Arora, Michelle Newell, Victoria L Bland, Jin Zhou, Nicola Pirastu, Jose M Ordovas, Yann C Klimentidis Apr 2022

Identification Of Genetic Loci Simultaneously Associated With Multiple Cardiometabolic Traits, Alexis C Wood, Amit Arora, Michelle Newell, Victoria L Bland, Jin Zhou, Nicola Pirastu, Jose M Ordovas, Yann C Klimentidis

Children’s Nutrition Research Center Staff Publications

Background and aims: Cardiometabolic disorders (CMD) arise from a constellation of features such as increased adiposity, hyperlipidemia, hypertension and compromised glucose control. Many genetic loci have shown associations with individual CMD-related traits, but no investigations have focused on simultaneously identifying loci showing associations across all domains. We therefore sought to identify loci associated with risk across seven continuous CMD-related traits.

Methods and results: We conducted separate genome-wide association studies (GWAS) for systolic and diastolic blood pressure (SBP/DBP), hemoglobin A1c (HbA1c), low- and high- density lipoprotein cholesterol (LDL-C/HDL-C), waist-to-hip-ratio (WHR), and triglycerides (TGs) in the UK Biobank (N = 356,574-456,823). Multiple …


Β-Carotene Oxygenase 2 Genotype Modulates The Impact Of Dietary Lycopene On Gene Expression During Early Tramp Prostate Carcinogenesis, Nancy E Moran, Jennifer M Thomas-Ahner, Joshua W Smith, Ceasar Silva, Noor A Hason, John W Erdman, Steven K Clinton Apr 2022

Β-Carotene Oxygenase 2 Genotype Modulates The Impact Of Dietary Lycopene On Gene Expression During Early Tramp Prostate Carcinogenesis, Nancy E Moran, Jennifer M Thomas-Ahner, Joshua W Smith, Ceasar Silva, Noor A Hason, John W Erdman, Steven K Clinton

Children’s Nutrition Research Center Staff Publications

Background: Epidemiologic studies suggest lycopene and tomato intake are inversely associated with human prostate cancer incidence. In the genetically driven murine prostate carcinogenesis model transgenic adenocarcinoma of the mouse prostate (TRAMP), prostate cancer is inhibited by feeding of lycopene or tomatoes, and these effects are modulated by the β-carotene oxygenase 2 (Bco2) genotype.

Objective: We sought insight into this interaction through evaluation of prostate gene expression patterns during early TRAMP carcinogenesis.

Methods: Three-week-old TRAMP/+ or TRAMP/- × Bco2+/+ or Bco2-/- mice were fed a control, lycopene beadlet, or 10% tomato powder-containing semipurified diet (providing 0, 384 and 462 mg lycopene/kg …


Metabolic Inflexibility In Youth With Obesity: Is It A Feature Of Obesity Or Distinctive Of Youth Who Are Metabolically Unhealthy?, Nour Y Gebara, Joon Young Kim, Fida Bacha, Sojung Lee, Silva Arslanian Apr 2022

Metabolic Inflexibility In Youth With Obesity: Is It A Feature Of Obesity Or Distinctive Of Youth Who Are Metabolically Unhealthy?, Nour Y Gebara, Joon Young Kim, Fida Bacha, Sojung Lee, Silva Arslanian

Children’s Nutrition Research Center Staff Publications

Background:

Individuals with obesity have metabolic inflexibility with diminished fasting fat oxidation and blunted increase in respiratory quotient (RQ) in insulin-stimulated states. However, it is unclear if metabolic inflexibility is a characteristic of obesity per se or is unique to youth who have metabolically unhealthy obesity (MUO) compared with metabolically healthy obesity (MHO).

Objective:

We investigated metabolic flexibility in youth with MUO, MHO and normal weight (NW) and compared their metabolic characteristics.

Patients/Design:

Youth (n=188) were divided, based on cut-off points for in vivo insulin sensitivity (IS) of adolescents with NW, into 137 with MUO and 51 with MHO. Fasting …


The Effects Of Mosaic Law Observance On Human Health, Emily Uhlmeyer Apr 2022

The Effects Of Mosaic Law Observance On Human Health, Emily Uhlmeyer

Senior Honors Theses

For the people of ancient Israel, life was guided and regulated by adherence to the law of Moses. Dietary restrictions, purification rituals, circumcision, and Sabbath observance were each critical components of this code and were meticulously detailed in the Old Testament, specifically in the Torah. Still today, dietary laws are observed and select rituals practiced by many Jews and Seventh Day Adventists. Although health protection was never the primary purpose of the law, noticeable effects on human health have been connected to its observance. Evaluation of the effects of the Levitical law on human health can be achieved by a …


The Role Of Mtorc1 In Autophagy As It Relates To Cancer, Olivia Robinson Apr 2022

The Role Of Mtorc1 In Autophagy As It Relates To Cancer, Olivia Robinson

Senior Honors Theses

The mammalian target of rapamycin complex 1, mTORC1, is composed of several subunit proteins with many cellular responsibilities including participation in a complex cell signaling cascade leading to autophagy, which is the regulated degradation of cell components. mTORC1 is frequently mutated or dysregulated within human cancer. Normally, mTORC1 functions to provide efficient regulation of autophagy according to intracellular levels of growth factors, amino acids, nutrients, oxygen levels, and more that can either inhibit mTORC1 and upregulate autophagy or activate mTORC1 and downregulate autophagy. A better understanding of mTORC1 is imperative to preparing cancer therapy treatments. Various cancerous tissue types require …


Hamstring And Quadriceps Strength Ratio In Collegiate Wrestlers, Jesse Redding Apr 2022

Hamstring And Quadriceps Strength Ratio In Collegiate Wrestlers, Jesse Redding

Senior Honors Theses

ACL injuries are a significant risk for athletes across sports. One of the sports that reports the highest rate of ACL injury is wrestling. The mechanism of injury among wrestlers appears to be unique and has limited data compared to other sports. Several nonmodifiable risk factors have been studied for ACL injury, as well as several modifiable risk factors that include BMI, muscular composition, and high-risk movements. The hamstring to quadriceps strength ratio (H:Q) is one aspect of muscular composition that has received little attention in collegiate wrestlers. The purpose of this study was to analyze the H:Q strength ratio …


Exploring Water Filtration Methods For Implementation In Rural Mozambique, Cole Glasson Apr 2022

Exploring Water Filtration Methods For Implementation In Rural Mozambique, Cole Glasson

Senior Honors Theses

Of Mozambicans living in rural areas, nearly two-thirds are without access to clean drinking water sources, leading to waterborne diseases and diarrhea. Thus, a great need exists for an effective and sustainable water treatment solution for rural Mozambicans. Boiling, solar disinfection, and membrane-based processes are analyzed with respect to their effectiveness and economic sustainability in an attempt to propose a solution to those living in rural Mozambique. The most sustainable option is membrane-based processes, with two particular systems showing the most promise: Skyhydrant™ and LifeStraw®. These two ultrafiltration system are extremely effective at retaining almost all forms of bacterial and …


Determining The Genomic Localization And Binding Partners Of Zinc Finger Protein 410, Mariko Locke Apr 2022

Determining The Genomic Localization And Binding Partners Of Zinc Finger Protein 410, Mariko Locke

Senior Honors Theses

The results of a folate deficiency study affecting cognition in mice suggested the altered genes may be controlled by a transcription factor known as Zinc Finger Protein 410 (Zfp410). Due to a lack of literature on Zfp410’s interacting proteins and DNA-binding location, our study aims to further elucidate the role Zfp410 plays in affecting cognition. A custom antibody was used to determine the Zfp410 isoforms present in mouse and rat brains. Moreover, the antibody was used to determine the binding partners of Zfp410 in the brain and locate specific genomic regions/sequences with which it associates in vivo. These results may …


Lived Experiences Of Adults Formally Raised By Grandparents On Their Connection To The School Community While In High School, Karen M. Maguire Apr 2022

Lived Experiences Of Adults Formally Raised By Grandparents On Their Connection To The School Community While In High School, Karen M. Maguire

All Theses And Dissertations

This qualitative interpretative phenomenological analysis sought to understand the lived experiences of connectedness to the secondary school community of children raised by grandparents, told from the reflective viewpoint of the grandchildren now as adults. Although the relationship between grandparents and the grandchildren they raise has been studied, how those grandchildren connect to the school community has yet to be explored and was the focus of this study. Research on grandchildren raised by grandparents and student connection to the school community provided valuable insight, highlighting the need for additional exploration in this area. Education researchers have studied student engagement quite thoroughly, …


Effectivenessofnursingguidelinesonnursesperformanceregardinghighalertmedications, Sara Sayed Abdalla Apr 2022

Effectivenessofnursingguidelinesonnursesperformanceregardinghighalertmedications, Sara Sayed Abdalla

Nursing

No abstract provided.


The Effect Of Gendered Scandals On The Passage Of Women’S Issues Legislation: Louisiana State University Title Ix Failures And The Elimination Of The Pink Tax, Rebecca Norton Apr 2022

The Effect Of Gendered Scandals On The Passage Of Women’S Issues Legislation: Louisiana State University Title Ix Failures And The Elimination Of The Pink Tax, Rebecca Norton

Honors Capstones

No abstract provided.