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Understanding Perceptions Of New-Onset Type 1 Diabetes Education In A Pediatric Tertiary Care Center, Gabriel Betancurvelez Jan 2023

Understanding Perceptions Of New-Onset Type 1 Diabetes Education In A Pediatric Tertiary Care Center, Gabriel Betancurvelez

Yale Medicine Thesis Digital Library

Background: Youth newly diagnosed with type 1 diabetes (T1D), and their families, require intensive education on the management of this chronic condition during this overwhelming period. Traditionally, our center conducts training in person during a hospital admission.

Methods: We studied family perceptions of our current patient education methods in an effort to elucidate strategies to augment education in the post-pandemic environment, where provider time in the room and visitation rules may limit face-to-face encounters.

Results: 25 families completed the survey (distributed to 156 in total, with approximately 21% response rate). The mean age at diagnosis was 9.52 ± 4.29 years …


The Association Between Social Needs Care Coordination And Social Needs Status Amongst Patients In A Federally Qualified Health Center, Autumn Nobles Jan 2023

The Association Between Social Needs Care Coordination And Social Needs Status Amongst Patients In A Federally Qualified Health Center, Autumn Nobles

Yale Medicine Thesis Digital Library

Social needs screenings within healthcare systems have grown more common with increasing discourse around the contribution of systemic determinants to health outcomes. These screenings have been used to describe the prevalence of social needs within communities but have not been evaluated for the impact that they and the interventions to which they are attached may have on health outcomes. Here we evaluate social needs screenings and their potential impact on patient health at a federally qualified health center in New Haven, Connecticut. We describe the baseline needs at the facility, evaluate change in reported social needs among patients undergoing screening, …


Examining Foods And Beverages Served And Child Food Insecurity Across Early Care And Education (Ece) Programs In Communities With High Rates Of Obesity And Food Insecurity, Deepa Srivastava, Lucy R. Zheng, Dipti A. Dev Jan 2023

Examining Foods And Beverages Served And Child Food Insecurity Across Early Care And Education (Ece) Programs In Communities With High Rates Of Obesity And Food Insecurity, Deepa Srivastava, Lucy R. Zheng, Dipti A. Dev

Department of Child, Youth, and Family Studies: Faculty Publications

The purpose of this study was to examine implementation of serving food and beverage evidence-based practices (nutrition EBPs) across CACFP participating licensed childcare centers (CCCs, n = 51) and family childcare homes (FCCHs, n = 49) in central California. Results indicated that FCCHs reported significantly higher (p < .05) implementation of nutrition EBPs and barriers than CCCs. Both CCCs and FCCHs refer families to WIC/SNAP when they observe child food insecurity and control how much food is served to children. It is important to consider organizational structure (CCCs, FCCHs) and child food insecurity when developing policies/interventions for improving implementation of nutrition EBPs in ECEs.


Public Reporting Of Monitorship Outcomes, Veronica Root Martinez Jan 2023

Public Reporting Of Monitorship Outcomes, Veronica Root Martinez

Faculty Scholarship

When a corporation engages in misconduct that is widespread or pervasive, courts, regulators, or prosecutors often insist that the firm obtain assistance from an independent third party — a monitor — to oversee the firm’s remediation effort. The largest firms in the world — from Deutsche Bank, to Volkswagen, to Carnival Cruise Lines — have found themselves having to retain a monitor for corporate misconduct, despite attempts to avoid a monitorship entirely. Traditionally, monitors, or their special master forebearers, were utilized by courts to assist in overseeing compliance with court orders, and their work was both accessible and transparent. As …


Acute Effects Of Sprint Interval Training And Blood Flow Restriction On Neuromuscular And Muscle Function, David Gonzalez Rojas Jan 2023

Acute Effects Of Sprint Interval Training And Blood Flow Restriction On Neuromuscular And Muscle Function, David Gonzalez Rojas

Electronic Theses and Dissertations, 2020-2023

The purpose of this investigation was to examine the effects of continuous (CBFR) and intermittent (IBFR) blood flow restriction (BFR) applied during sprint interval training (SIT) on performance, muscle, and neuromuscular function. Fifteen men completed SIT with CBFR, IBFR, and No-BFR. Each SIT bout consisted of 2, 30-s maximal sprints on a cycle ergometer with a resistance of 7.5% of body mass. Concentric peak torque (CPT), maximal voluntary isometric contraction (MVIC) torque, and muscle thickness (MT) were measured before and after the SIT protocols during each visit. During the maximal strength assessments, surface electromyography (sEMG) was recorded and during each …


Comparative Effect Of Probiotic And/Or Canola Seed, Canola Meal And Canola Oil Dietary Supplementation On Growth Performance, Blood Component, Antioxidant Status And Immune Response In Growing Rabbits, Merna M. M. Al-Rakhawi, Hayam M. A. Abo El-Maaty, Engy F. Risha, Fatma M. Abdelhamid Jan 2023

Comparative Effect Of Probiotic And/Or Canola Seed, Canola Meal And Canola Oil Dietary Supplementation On Growth Performance, Blood Component, Antioxidant Status And Immune Response In Growing Rabbits, Merna M. M. Al-Rakhawi, Hayam M. A. Abo El-Maaty, Engy F. Risha, Fatma M. Abdelhamid

Mansoura Veterinary Medical Journal

Objective: This study investigated the effects of probiotics- Progut® (PG) and/or canola seed (CS), canola meal (CM), and canola oil (CO) on the growth performance, blood components, antioxidant status, and immune response in rabbits.

Design: Randomized controlled study.

Animals: One hundred and twenty rabbits were used.

Procedures: Rabbits were assigned into 8 groups: control non supplemented group and the other supplemented groups including; PG, CS , CS+PG , CM, CM+PG, CO, and CO+PG. Growth performance, liver and kidney biomarkers, lipid profile, antioxidant markers, and immunological parameters were determined at the end of the study.

Results:. CM and CO had the …


Pathological, Ultrastructural And Haematological Studies On The Simultaneous Effect Of Dietary Supplementation With Lauric And Benzoic Acids On Nile Tilapia, Abdelaziz M. Rabea, Iman Ibrahim, Hebatallah A. Mahgoub, Ahmed El- Shaieb Jan 2023

Pathological, Ultrastructural And Haematological Studies On The Simultaneous Effect Of Dietary Supplementation With Lauric And Benzoic Acids On Nile Tilapia, Abdelaziz M. Rabea, Iman Ibrahim, Hebatallah A. Mahgoub, Ahmed El- Shaieb

Mansoura Veterinary Medical Journal

Objective: To evaluate the simultaneous effect of dietary acidifier lauric and benzoic acids on immunohematological parameters and histopathological changes in O. niloticus.

Design: Randomized controlled study.

Animal Models: The experiment was performed on 120 juvenile Nile tilapia weighing (50 ± 6.14 g).

Procedures: Fish were divided into four experimental groups (30 fish/group): Control group received normal diet; Benzoic Acid group was supplemented with benzoic acid 1 g/kg diet); Lauric Acid group was supplemented with lauric acid (1 g/kg diet); combination group was supplemented with benzoic acid (1 g/kg diet) and lauric acid (1 g/kg diet). Supplements were applied for 30 …


Investigation Of Nile Tilapia Mortalities During Summer 2019 In El-Manzala Fish Farms In Dakahlia Governorate, Egypt, Amira M. M. El- Sherbiny, Moustafa M. S. Fouda, Medhat S. Shakweer, Viola H. Zaki Jan 2023

Investigation Of Nile Tilapia Mortalities During Summer 2019 In El-Manzala Fish Farms In Dakahlia Governorate, Egypt, Amira M. M. El- Sherbiny, Moustafa M. S. Fouda, Medhat S. Shakweer, Viola H. Zaki

Mansoura Veterinary Medical Journal

Objective: To identify suspected causes of mass mortality in Oreochromis niloticus at El-Manzala fish farms in Dakahlia Governorate, Egypt, during disease outbreaks in the summer of 2019.

Design: Observational study.

Animals: Two hundred diseased and freshly dead Oreochromis niloticus (Nile tilapia) weighting 100-150 g.

Procedures: Collected fish samples were subjected to clinical, postmortem and bacteriological investigations regarding histopathological alterations, pathogenicity tests, and antibiogram susceptibility of the main isolated bacterial species.

Results: A total of 286 bacterial isolates were detected from all examined fish samples. Bacteriological examination revealed that all bacteria were gram-negative rods, which were identified as A. hydrophila (43.36%), …


Protective Effects Of Nanoselenium On Japanese Quails Fed On Aflatoxin B1 Contaminated Diets On Performance Parameters, Hematological, Biochemical, Immunological And Pathological Studies, Hend D. Elbar, Walaa F. Awadin, Abeer E. Aziza, Ahmed El-Shaieb Jan 2023

Protective Effects Of Nanoselenium On Japanese Quails Fed On Aflatoxin B1 Contaminated Diets On Performance Parameters, Hematological, Biochemical, Immunological And Pathological Studies, Hend D. Elbar, Walaa F. Awadin, Abeer E. Aziza, Ahmed El-Shaieb

Mansoura Veterinary Medical Journal

Mycotoxins are considered to be a destructive problem in feed and food quality for animal and human health. Our study aimed to investigate the toxic effects of AFB1in addition to the protective effects of nano-Se against aflatoxicosis in quails. One hundred and twenty healthy Japanese quails were randomly divided into five groups of 24 birds each. First group; fed basal diet (negative control) without any addition, Second group; fed basal diet supplemented with 0.5 mg/kg diet nano-Se, Third group; fed basal diet containing 300 ppb AFB1 (positive control), Fourth group; fed basal diet containing 300 ppb AFB1 treated with 0.3 …


An Overview Of Meat Composition, Postmortem Changes, And Sources Of Microbial Contamination In Developing Countries Abattoirs, Hend Ali Elshebrawy, Nahed Gomaa Kasem, Khalid Ibrahim Sallam Jan 2023

An Overview Of Meat Composition, Postmortem Changes, And Sources Of Microbial Contamination In Developing Countries Abattoirs, Hend Ali Elshebrawy, Nahed Gomaa Kasem, Khalid Ibrahim Sallam

Mansoura Veterinary Medical Journal

Meat is an essential component of a healthy and well-balanced diet and has played a crucial role in human evolution over the years because it is an excellent source of highly digested protein, vitamin B12, vitamin B6, niacin, iron, copper, zinc, and selenium. Raw meat is considered an unavoidable source of microbial contamination due to its enriched nutrient composition, high pH (5.5 to 6.5), and water activity (0.98 to 0.99); consequently, the meat is regarded as a perfect medium for bacterial growth. Meat deterioration begins immediately after slaughter because of faulty practices during the processing stages such as skinning, evisceration, …


Teratogenic Effect Of Fluconazole On Rabbit’S Foeti, Sally I. Ismael, Magdy S. Amer, Gehan N. Gad, Rasha A. El-Galil, Sara T. Elazab Jan 2023

Teratogenic Effect Of Fluconazole On Rabbit’S Foeti, Sally I. Ismael, Magdy S. Amer, Gehan N. Gad, Rasha A. El-Galil, Sara T. Elazab

Mansoura Veterinary Medical Journal

bjective: ThisThe current study aimedwas designed to assess the teratogenic effect of fluconazole on developing rabbits’ foeti.

Design: Randomized controlled study.

Animals: Twenty-four sexually mature females and two2 adult males New Zealand white rabbits (, 5–- 6 months old, weighing 3-4 kg, were used in this study. The Mmature males were used for mating. process

Procedure: The Ppregnant female rabbits (n = 24) were allotted into four4 groups (6 rabbits/ group). The cControl group (G1) was administered normal saline. Other groups were administeredgiven fluconazole orally at a dose of 80 mg/kg once daily for ten days either ion the first …


Knowledge About Vitamin D Among Women In The United Arab Emirates, Sharifa Alblooshi, Fatme Al Anouti, Rafiq Hijazi Jan 2023

Knowledge About Vitamin D Among Women In The United Arab Emirates, Sharifa Alblooshi, Fatme Al Anouti, Rafiq Hijazi

All Works

Vitamin D deficiency is a significant public health issue as it affects almost 90% of the United Arab Emirates (UAE) population. A bigger portion of this percentage is women due to the physiological changes throughout their life cycle. This study aims to assess the knowledge about vitamin D among women in the UAE. This is a quantitative cross-sectional study. Using snowball sampling, an electronic questionnaire was sent to women aged 18 years and above. Overall, 1537 women completed the questionnaire. The participants had mean scores of 49.4 ± 10.7 and 59.6 ± 14.6 for general and nutritional knowledge, respectively. Factors …


Association Between Self-Reported Polycystic Ovary Syndrome With Chronic Diseases Among Emiratis: A Cross-Sectional Analysis From The Uae Healthy Future Study, Nirmin F. Juber, Abdishakur Abdulle, Abdulla Aljunaibi, Abdulla Alnaeemi, Amar Ahmad, Andrea Leinberger-Jabari, Ayesha S. Al Dhaheri, Eiman Alzaabi, Fatma Al-Maskari, Fatme Alanouti, Habiba Alsafar, Juma Alkaabi, Laila Abdel Wareth, Mai Aljaber, Marina Kazim, Michael Weitzman, Mohammad Al-Houqani, Mohammed Hag-Ali, Naima Oumeziane, Scott Sherman, Syed M. Shah, Wael Almahmeed, Youssef Idaghdour, Tom Loney, Omar El-Shahawy, Raghib Ali Jan 2023

Association Between Self-Reported Polycystic Ovary Syndrome With Chronic Diseases Among Emiratis: A Cross-Sectional Analysis From The Uae Healthy Future Study, Nirmin F. Juber, Abdishakur Abdulle, Abdulla Aljunaibi, Abdulla Alnaeemi, Amar Ahmad, Andrea Leinberger-Jabari, Ayesha S. Al Dhaheri, Eiman Alzaabi, Fatma Al-Maskari, Fatme Alanouti, Habiba Alsafar, Juma Alkaabi, Laila Abdel Wareth, Mai Aljaber, Marina Kazim, Michael Weitzman, Mohammad Al-Houqani, Mohammed Hag-Ali, Naima Oumeziane, Scott Sherman, Syed M. Shah, Wael Almahmeed, Youssef Idaghdour, Tom Loney, Omar El-Shahawy, Raghib Ali

All Works

Purpose: This study aimed to assess the prevalence of self-reported polycystic ovary syndrome (PCOS) among Emiratis and examine bi-directional associations of PCOS with self-reported chronic diseases, namely: diabetes, asthma, high cholesterol, and high blood pressure. Patients and Methods: A cross-sectional analysis was performed using the UAE Healthy Future Study (UAEHFS) data collected from February 2016 to April 2022 involving 1040 Emirati women aged 25–67 years from recruitment centers in the United Arab Emirates (UAE). The bi-directional associations between self-reported PCOS and self-reported chronic diseases were evaluated by establishing temporality based on reported age-at-diagnoses. Firstly, the associations between PCOS (diagnosed at …


Bacterial Pneumonia Associated With Multidrug-Resistant Gram-Negative Pathogens: Understanding Epidemiology, Resistance Patterns, And Implications With Covid-19, Dalal Hammoudi Halat, Carole Ayoub Moubareck Jan 2023

Bacterial Pneumonia Associated With Multidrug-Resistant Gram-Negative Pathogens: Understanding Epidemiology, Resistance Patterns, And Implications With Covid-19, Dalal Hammoudi Halat, Carole Ayoub Moubareck

All Works

The ongoing spread of antimicrobial resistance has complicated the treatment of bacterial hospital-acquired pneumonia (HAP) and ventilator-associated pneumonia (VAP). Gram-negative pathogens, especially those with multidrug-resistant profiles, including Escherichia coli, Klebsiella pneumoniae, Enterobacter spp., Pseudomonas aeruginosa, and Acinetobacter spp., are an important culprit in this type of infections. Understanding the determinants of resistance in pathogens causing pneumonia is ultimately stressing, especially in the shadows of the COVID-19 pandemic, when bacterial lung infections are considered a top priority that has become urgent to revise. Globally, the increasing prevalence of these pathogens in respiratory samples represents a significant infection challenge, with major limitations …


Keeping The Ball Alive: The Marriage Between Sports And Acting, Giuseppe Pipicella Jan 2023

Keeping The Ball Alive: The Marriage Between Sports And Acting, Giuseppe Pipicella

Electronic Theses and Dissertations, 2020-2023

This thesis examines the link between sports and theatre from the actor's perspective and concludes that these two practices should be used together to achieve optimal performance. Using context provided by great physical theatre practitioners such as Jacques LeCoq, Vsevolod Meyerhold, and Rudolf Von Laban, the candidate used his past experience as a gymnast and a soccer player, and the teachings of Timothy Gallwey's The Inner Game of Tennis, to craft a rehearsal and performance regimen for Theatre UCF's production of Paula Vogel's Indecent. This regimen included an experiment where he alternated days in which he swam to days in …


Time Of Day Effects On Maximal Effort Strength/Power And Fatigability Assessments, Justine Renziehausen Jan 2023

Time Of Day Effects On Maximal Effort Strength/Power And Fatigability Assessments, Justine Renziehausen

Electronic Theses and Dissertations, 2020-2023

The circadian rhythm is a 24-hour cycle present within most biological systems that is controlled by the suprachiasmatic nucleus (SCN) of the hypothalamus. The SCN is responsible for synchronizing the peripheral "clocks" present in other tissues so that all rhythms, such as heart rate, body temperature, and hormone secretion, are functioning together. As most systems experience a circadian rhythm, physical performance likely does as well. Previous studies have investigated time of day effects on maximal strength, power, and endurance performance, however, factors (e.g., sex, chronotype, age, etc.) have not clearly been distinguished. Additionally, body temperature has been suggested to be …


Synthesis, Characterization, And Application Of Zif-8 For Removal Of Cd, Ni, And Pb Ions From Aqueous Solutions: Optimization Of The Process By Response Surface Methodology (Rsm) Based On Central Composite Design (Ccd) Technique, Amir Khosravi, Maryam Randjbar, Razieh Habibpour Jan 2023

Synthesis, Characterization, And Application Of Zif-8 For Removal Of Cd, Ni, And Pb Ions From Aqueous Solutions: Optimization Of The Process By Response Surface Methodology (Rsm) Based On Central Composite Design (Ccd) Technique, Amir Khosravi, Maryam Randjbar, Razieh Habibpour

Journal of Metals, Materials and Minerals

A Zeolitic imidazolate framework-8 (ZIF-8) was synthesized by the solvothermal method of zinc nitrate hexahydrate and 2-methylimidazole in DMF to remove Cd(II), Ni(II), and Pb(II) ions from aqueous solutions. The synthesized ZIF-8 was distinguished by XRD, FT-IR, BET, SEM, EDX, TEM methods. Several significant variables were optimized with response surface methodology (RSM) to obtain the highest removal of metal ions. According to the achieved results, the aqueous solution pH values of 6.5, 6.5, and 6.0, ZIF-8 dosages of 0.05, 0.06, and 0.05 g⸳L-1, and metal ions initial concentrations of 50, 60, and 60 mg⸳L-1 were chosen as the optimum amount …


It Doesn't Matter What "Interpretation" Is, Francisco J. Urbina Jan 2023

It Doesn't Matter What "Interpretation" Is, Francisco J. Urbina

Journal Articles

Reviewing: HOW TO INTERPRET THE CONSTITUTION? By Cass Sunstein. Princeton, NJ: Princeton University Press. 2023. Pp. IX + 195. $22.95 (hardcover).


Low Motor Dexterity And Significant Behaviors Following Hospitalized Isolation In Children, Kaitlin Fraser, Miriam Kuhn, Rebecca K. Swanson, Don W. Coulter, Christopher Copeland, Jorge M. Zuniga Jan 2023

Low Motor Dexterity And Significant Behaviors Following Hospitalized Isolation In Children, Kaitlin Fraser, Miriam Kuhn, Rebecca K. Swanson, Don W. Coulter, Christopher Copeland, Jorge M. Zuniga

Journal Articles: College of Nursing

The main objective of this study was to describe the cortical patterns of brain activity during a gross dexterity task and develop a behavioral profile of children experiencing isolation. A cross-sectional assessment was conducted during one visit. Sample: Four pediatric patients who had undergone isolation within a hospital comprised the full data collection. During the collection, participants completed the Box and Blocks Test of gross manual dexterity while undergoing imaging of the motor cortex using functional near-infrared spectroscopy. Participants also completed a Behavioral Assessment System for Children, Third Edition (BASC-3) self-report, which was analyzed along with a parent report to …


Red Cabbage Juice-Mediated Gut Microbiota Modulation Improves Intestinal Epithelial Homeostasis And Ameliorates Colitis, Emily Jean Wilson, Nagabhishek Sirpu Natesh, Parsa Ghadermazi, Ramesh Pothuraju, Dipakkumar R. Prajapati, Sanjit Pandey, Jussuf T. Kaifi, John R. Dodam, Jeffrey N. Bryan, Christian L. Lorson, Aude A. Watrelot, Jason M. Foster, Thomas J. Mansell, Siu Hung Joshua Chan, Surinder K. Batra, Jeyamkondan Subbiah, Satyanarayana Rachagani Jan 2023

Red Cabbage Juice-Mediated Gut Microbiota Modulation Improves Intestinal Epithelial Homeostasis And Ameliorates Colitis, Emily Jean Wilson, Nagabhishek Sirpu Natesh, Parsa Ghadermazi, Ramesh Pothuraju, Dipakkumar R. Prajapati, Sanjit Pandey, Jussuf T. Kaifi, John R. Dodam, Jeffrey N. Bryan, Christian L. Lorson, Aude A. Watrelot, Jason M. Foster, Thomas J. Mansell, Siu Hung Joshua Chan, Surinder K. Batra, Jeyamkondan Subbiah, Satyanarayana Rachagani

Journal Articles: Biochemistry & Molecular Biology

Gut microbiota plays a crucial role in inflammatory bowel diseases (IBD) and can potentially prevent IBD through microbial-derived metabolites, making it a promising therapeutic avenue. Recent evidence suggests that despite an unclear underlying mechanism, red cabbage juice (RCJ) alleviates Dextran Sodium Sulfate (DSS)-induced colitis in mice. Thus, the study aims to unravel the molecular mechanism by which RCJ modulates the gut microbiota to alleviate DSS-induced colitis in mice. Using C57BL/6J mice, we evaluated RCJ's protective role in DSS-induced colitis through two cycles of 3% DSS. Mice were daily gavaged with PBS or RCJ until the endpoint, and gut microbiota composition …


Something Smells Fishy: How Lipid Mediators Impact The Maternal-Fetal Interface And Neonatal Development, Maranda Thompson, Arzu Ulu, Maheswari Mukherjee, Ana G. Yuil-Valdes, Melissa K. Thoene, Matthew Van Ormer, Rebecca Slotkowski, Teri Mauch, Ann Anderson-Berry, Corrine K. Hanson, Tara M. Nordgren, Sathish Kumar Natarajan Jan 2023

Something Smells Fishy: How Lipid Mediators Impact The Maternal-Fetal Interface And Neonatal Development, Maranda Thompson, Arzu Ulu, Maheswari Mukherjee, Ana G. Yuil-Valdes, Melissa K. Thoene, Matthew Van Ormer, Rebecca Slotkowski, Teri Mauch, Ann Anderson-Berry, Corrine K. Hanson, Tara M. Nordgren, Sathish Kumar Natarajan

Journal Articles: Pediatrics

Normal pregnancy relies on inflammation for implantation, placentation, and parturition, but uncontrolled inflammation can lead to poor maternal and infant outcomes. Maternal diet is one modifiable factor that can impact inflammation. Omega-3 and -6 fatty acids obtained through the diet are metabolized into bioactive compounds that effect inflammation. Recent evidence has shown that the downstream products of omega-3 and -6 fatty acids may influence physiology during pregnancy. In this review, the current knowledge relating to omega-3 and omega-6 metabolites during pregnancy will be summarized.


Ventricular Tachycardia In A Pediatric Patient With High-Risk Thrombotic Thrombocytopenia Purpura, Taylor J. Kratochvil, Jeffrey A. Robinson Jan 2023

Ventricular Tachycardia In A Pediatric Patient With High-Risk Thrombotic Thrombocytopenia Purpura, Taylor J. Kratochvil, Jeffrey A. Robinson

Journal Articles: Pediatrics

An 8-year-old previously healthy male was diagnosed with thrombotic thrombocytopenic purpura (TTP) and increased serum cardiac troponin I. Telemetry recorded non-sustained ventricular tachycardia, without ST-segment changes or other abnormalities on serial electrocardiogram. This case illustrates that cardiac monitoring by telemetry should be considered in high-risk TTP with elevated cardiac troponin.


Retinol And Pro-Vitamin A Carotenoid Nutritional Status During Pregnancy Is Associated With Newborn Hearing Screen Results, Rebecca Slotkowski, Matthew Van Ormer, Anum Akbar, Olivia Paetz, Taija Hahka, Maranda Thompson, Alyssa Freeman, Alexandra Hergenrader, Sarah Sweeney, Zeljka Korade, Thiago Genaro-Mattos, Corrine K. Hanson, Ann Anderson-Berry, Melissa K. Thoene Jan 2023

Retinol And Pro-Vitamin A Carotenoid Nutritional Status During Pregnancy Is Associated With Newborn Hearing Screen Results, Rebecca Slotkowski, Matthew Van Ormer, Anum Akbar, Olivia Paetz, Taija Hahka, Maranda Thompson, Alyssa Freeman, Alexandra Hergenrader, Sarah Sweeney, Zeljka Korade, Thiago Genaro-Mattos, Corrine K. Hanson, Ann Anderson-Berry, Melissa K. Thoene

Journal Articles: Pediatrics

The prenatal period is critical for auditory development; thus, prenatal influences on auditory development may significantly impact long-term hearing ability. While previous studies identified a protective effect of carotenoids on adult hearing, the impact of these nutrients on hearing outcomes in neonates is not well understood. The purpose of this study is to investigate the relationship between maternal and umbilical cord plasma retinol and carotenoid concentrations and abnormal newborn hearing screen (NHS) results. Mother-infant dyads (n = 546) were enrolled at delivery. Plasma samples were analyzed using HPLC and LC-MS/MS. NHS results were obtained from medical records. Statistical analysis …


Plasma Retinol Concentrations And Dietary Intakes Of Mother-Infant Sets In Singleton Versus Twin Pregnancy, Anum Akbar, Sarah Duvall, Matthew Van Ormer, Rebecca Slotkowski, Taija Hahka, Thiago Genaro-Mattos, Zeljka Korade, Corrine K. Hanson, Ann Anderson-Berry, Melissa K. Thoene Jan 2023

Plasma Retinol Concentrations And Dietary Intakes Of Mother-Infant Sets In Singleton Versus Twin Pregnancy, Anum Akbar, Sarah Duvall, Matthew Van Ormer, Rebecca Slotkowski, Taija Hahka, Thiago Genaro-Mattos, Zeljka Korade, Corrine K. Hanson, Ann Anderson-Berry, Melissa K. Thoene

Journal Articles: Pediatrics

Vitamin A (retinol) is essential for normal fetal development, but the recommendation for maternal dietary intake (Retinol Activity Equivalent, RAE) does not differ for singleton vs. twin pregnancy, despite the limited evaluation of retinol status. Therefore, this study aimed to evaluate plasma retinol concentrations and deficiency status in mother-infant sets from singleton vs. twin pregnancies as well as maternal RAE intake. A total of 21 mother-infant sets were included (14 singleton, 7 twin). The HPLC and LC-MS/HS evaluated the plasma retinol concentration, and data were analyzed using the Mann-Whitney U test. Plasma retinol was significantly lower in twin vs. singleton …


Evaluation Of Vitamin E Isoforms In Placental Tissue And Their Relationship With Maternal Dietary Intake And Plasma Concentrations In Mother-Infant Dyads, Ishani Jhamb, Alyssa Freeman, Michelle R. Lotfi, Matthew Van Ormer, Corrine K. Hanson, Ann Anderson-Berry, Melissa K. Thoene Jan 2023

Evaluation Of Vitamin E Isoforms In Placental Tissue And Their Relationship With Maternal Dietary Intake And Plasma Concentrations In Mother-Infant Dyads, Ishani Jhamb, Alyssa Freeman, Michelle R. Lotfi, Matthew Van Ormer, Corrine K. Hanson, Ann Anderson-Berry, Melissa K. Thoene

Journal Articles: Pediatrics

α-tocopherol is a vitamin E isoform with potent antioxidant activity, while the γ-tocopherol isoform of vitamin E exerts more pro-inflammatory effects. In maternal-fetal environments, increased plasma α-tocopherol concentrations are associated with positive birth outcomes, while higher γ-tocopherol concentrations are linked with negative pregnancy outcomes. However, little is known about tocopherol concentrations in placental tissue and their role in modulating placental oxidative stress, a process that is implicated in many complications of pregnancy. The objectives of this research are to evaluate the concentrations of α- and γ-tocopherol in placental tissue and assess relationships with maternal and umbilical cord plasma concentrations. A …


The Relationship Between Nutrition, Gut Dysbiosis, And Pediatric Sickle Cell Pain Outcomes: A Pilot Study, Chinenye R. Dike, Corrine K. Hanson, Dele Davies, Stephen Obaro, Fang Yu, James L. Harper, Helen Grace, Jeffrey Lebensburger, Chittalsinh M. Raulji, Jihyun Ma, Peter Mannon Jan 2023

The Relationship Between Nutrition, Gut Dysbiosis, And Pediatric Sickle Cell Pain Outcomes: A Pilot Study, Chinenye R. Dike, Corrine K. Hanson, Dele Davies, Stephen Obaro, Fang Yu, James L. Harper, Helen Grace, Jeffrey Lebensburger, Chittalsinh M. Raulji, Jihyun Ma, Peter Mannon

Journal Articles: Pediatrics

BACKGROUND: Nutritional deficiencies are prevalent in sickle cell disease (SCD) and may be associated with worse pain outcomes. Gut dysbiosis has been reported in patients with SCD and may contribute to both nutritional deficiencies and pain.

OBJECTIVES: We tested the association of nutrition, fat-soluble vitamin (FSV) deficiency, and gut microbiome composition on clinical outcomes in SCD. Second, we measured the association between diet and exocrine pancreatic function on FSV levels.

METHODS: Using case control design, we enrolled children with SCD (n = 24) and matched healthy controls (HC; n = 17, age, sex, race/ethnicity). Descriptive statistics summarized demographic and clinical …


Reflections On “Personal Responsibility” After Covid And Dobbs: Doubling Down On Privacy, Susan Frelich Appleton, Laura A. Rosenbury Jan 2023

Reflections On “Personal Responsibility” After Covid And Dobbs: Doubling Down On Privacy, Susan Frelich Appleton, Laura A. Rosenbury

Scholarship@WashULaw

This essay uses lenses of gender, race, marriage, and work to trace understandings of “personal responsibility” in laws, policies, and conversations about public support in the United States over three time periods: (I) the pre-COVID era, from the beginning of the American “welfare state” through the start of the Trump administration; (II) the pandemic years; and (III) the present post-pandemic period. We sought to explore the possibility that COVID and the assistance programs it inspired might have reshaped the notion of personal responsibility and unsettled assumptions about privacy and dependency. In fact, a mixed picture emerges. On the one hand, …


Essays On Race And Finance, Tian Qiu Jan 2023

Essays On Race And Finance, Tian Qiu

Theses and Dissertations--Finance and Quantitative Methods

In my first chapter, I show a positive municipal financing shock has heterogeneous effects on academic achievement. White students show meaningful improvement, but Black and Hispanic students do not. Consequently, the achievement racial gap widens following the shock. Changes in school funding do not explain this phenomenon; rather, it is explained by heterogeneous outcomes in household Socioeconomic Status (SES). These results highlight the possibility that a credit shock-induced increase in government spending could unexpectedly increase the local racial disparity. The second chapter examines the role of race and racial concordance between financial advisors and their local community. There are significant …


The Impact Of Effective Motivation Strategies On Student Engagement In Secondary Physical Education Classrooms, Devin Wortman Jan 2023

The Impact Of Effective Motivation Strategies On Student Engagement In Secondary Physical Education Classrooms, Devin Wortman

Education Theses

Properly motivating students is not only the backbone of academic success but positive in-class experiences. When students are having more positive classroom experiences, they will ultimately be more motivated to engage and succeed. More and more students today are choosing not to take physical education in school. A lack of self-confidence and a general interest in the subject are two of the many factors associated with this problem. With the help of intrinsic motivation and self-determination theory, this thesis will seek to answer the question: What impact does effective motivation have on secondary students’ willingness to participate in physical education …


Jiquilisco Bay Mangrove Restoration Center, Julio Romero Jan 2023

Jiquilisco Bay Mangrove Restoration Center, Julio Romero

Architecture Theses and Projects

Due to advanced degradation of mangroves, local ecosystems and social structures suffer. Non-profit organizations, consisting of community volunteers and researchers from abroad, are on the forefront of these restoration practices. Protecting these forests prevents local families from starving and keeps their homes from flooding. Applying research-based thinking to create a lab and education space for better implementation of restoration policies on a site-by-site basis was crucial, and the result was a low-tech space with serious material considerations based on local construction and best practices based on improvements in relatively low-tech seismic and water impermeable technology. The result is a celebration …