Digital Commons Network^™

Metabolomics Unveiled: Decoding Platelet Dynamics In Smokers, And Head-Neck Cancer Patients, Anthony Nasr Tanios

Theses and Dissertations

This study aimed to investigate the metabolomics profiles of platelets in smokers and head and neck cancer patients compared to normal healthy donors. This study analyzed the metabolomics profile of the platelets from smokers and cancer patients compared to healthy individuals. Samples were collected and processed by the research group of Prof. Dr. Barbara Wollenberg at the Klinikum Rechts der Isar-Technical University of Munich. The data analysis was performed at the Technical University in Munich (TUM). Untargeted metabolomics profiling was conducted using both hydrophilic interaction liquid chromatography (HILIC) and reverse-phase (RP) chromatography in both positive and negative ionization modes. This …

Lifelong Fitness In Ambulatory Children And Adolescents With Cerebral Palsy I: Key Ingredients For Bone And Muscle Health, Noelle G. Moreau, Kathleen M. Friel, Robyn K. Fuchs, Sudarshan Dayanidhi, Theresa Sukal-Moulton, Marybeth Grant-Beuttler, Mark D. Peterson, Richard D. Stevenson, Susan V. Duff

Physical Therapy Faculty Articles and Research

Physical activity of a sufficient amount and intensity is essential to health and the prevention of a sedentary lifestyle in all children as they transition into adolescence and adulthood. While fostering a fit lifestyle in all children can be challenging, it may be even more so for those with cerebral palsy (CP). Evidence suggests that bone and muscle health can improve with targeted exercise programs for children with CP. Yet, it is not clear how musculoskeletal improvements are sustained into adulthood. In this perspective, we introduce key ingredients and guidelines to promote bone and muscle health in ambulatory children with …

First Things First: Widespread Nutrient Deficiencies Limit Yields In Smallholder Oil Palm Fields, Hendra Sugianto, Juan Pablo Monzon, Iput Pradiko, Fatima A. Tenorio, Ya Li Lim, Christopher R. Donough, Sunawan, Suroso Rahutomo, Fahmuddin Agus, James Cock, Joni Amsar, Rana Farrasati, Ridho Iskandar, Juan I. Rattalino Edreira, Shofia Saleh, Heri Santoso, Antonius P. Tito, Nadib Ulfaria, Maja A. Slingerland, Patricio Grassini

Department of Agronomy and Horticulture: Faculty Publications

CONTEXT: Indonesia is the most important oil palm producing country. Nearly 40% of planted area is managed by smallholders, with yields well below the potential. Efforts to increase productivity have focused on the source of planting material, with little attention paid to plant nutrition.

OBJECTIVE: To assess the degree to which current productivity in smallholder oil palm fields is limited by nutrients in scenarios with distinct sources of planting material.

METHODS: We collected detailed data on leaf nutrient concentration from 30 fields to derive minimum sampling size needed to diagnose nutrient status. Subsequently, we collected data on …

Impacts Of Microrna-483 On Human Diseases, Katy Matson, Aaron B. Macleod, Nirali Mehta, Ellie Sempek, Xiaoqing Tang

Michigan Tech Publications, Part 1

MicroRNAs (miRNAs) are short non-coding RNA molecules that regulate gene expression by targeting specific messenger RNAs (mRNAs) in distinct cell types. This review provides a com-prehensive overview of the current understanding regarding the involvement of miR-483-5p and miR-483-3p in various physiological and pathological processes. Downregulation of miR-483-5p has been linked to numerous diseases, including type 2 diabetes, fatty liver disease, diabetic nephropathy, and neurological injury. Accumulating evidence indicates that miR-483-5p plays a crucial protective role in preserving cell function and viability by targeting specific transcripts. Notably, elevated levels of miR-483-5p in the bloodstream strongly correlate with metabolic risk factors and …

In Vivo Anti-Inflammatory Activity Of Coconut (Cocos Nucifera) Shell Liquid Smoke (Csls) For Hepatic Injury In Sprague-Dawley Rats, Loriz P. Cuizon, Alissa Joyce S. Comidoy, Michaella Angelene B. Ignalig, John Mark Villamor, Sophia Janine A. Lapatha

DLSU Senior High School Research Congress

Hepatic injury is an infection and virus-induced inflammation of the liver that can result in numerous medical conditions. As a response, this study utilizes an abundant resource found in the Philippines which is Coconut (Cocos nucifera), specifically, the coconuts’ shells, which have phenolic compounds that are essential for the suppression of inflammation. These Coconut shells undergo pyrolysis and distillation to produce the Coconut shell liquid smoke (CSLS) which is a digestible aqueous solution. Its efficacy in intervening with hepatic injury was tested through In-vivo experimentation with Sprague Dawley rats. Twelve (n=12) rats are injected with 10 mg/kg of Cisplatin to …

Anti-Fertility Potential Of Carica Papaya L. (Pawpaw) In Males, Maxene Erich L. Dela Cruz, Akhisha Prakash Babani, Arthea Julienne C. Lu, Riene Kyla P. Del Rosario, Jessamine Gail M. Inson

DLSU Senior High School Research Congress

The use of herbal contraceptives in males as an alternative to traditional contraceptives is an increasing method of preventing unintended pregnancies in women. To prevent adverse effects of contraceptives in women such as amenorrhea, bleeding, and vaginal pain, alternative male contraceptives are recommended. This review discussed the various compounds in the Carica papaya L. (C. papaya) plant that have antifertility properties and characterized the effects of its various parts, such as the seeds, leaves, stems, fruit pulps, and roots, on the testes, spermatozoa, sperm motility, sperm morphology, seminiferous tubules, and testosterone levels of male rodents. Reliable search engines such as …

Antimicrobial And Antioxidant Properties Of Oregano (Origanum Vulgare L.) Leaves As An Additive For Food Preservation In Bread Flour Products, Willwinrich M. Gomez, Katherine Yancy D. Yasoña, Danah Charisse T. Loterte

DLSU Senior High School Research Congress

This research assessed the effectiveness of oregano (Origanum vulgare L.) extract, specifically its antimicrobial and antioxidant properties, as an additive for a bread flour-based product. The infusion method was used to infuse the oregano leaves which were then infused into the dough of the pandesal with 1.5% concentration and 0.11% calcium propionate. It was compared to a control group with 0.33% calcium propionate. To evaluate its antioxidant and antimicrobial properties, the researchers tested rancidity through Peroxide Value Assay (PVA) to gauge the oxidative rancidity, and Yeast and Mold Count (YMC) to detect the growth of yeast and mold colonies that …

Assessing The Effect Of Fertigroe® Application On The Growth And Yield Of Raniag Potato Variety, Mikhaela Kathrina H. Dizon, Angel G. Po, Jolene Lynette A. Shi, Jazlyn Daniella C. So

DLSU Senior High School Research Congress

A fertilizer is a substance incorporated into the soil to increase soil fertility, plant nutrients, and crop cultivation. However, most fast-release fertilizers available in the market engender soil deterioration, which leads to environmental degradation and food insecurity. Past researchers have analyzed the effect of numerous fertilizers on potato production, although few have explored slow-release types. In this study, experimentations were carried out to discover the efficacy of FertiGroe®, a slow-release nanofertilizer known to improve a plant’s nutrient uptake and crop yield while being less harmful to the environment. The specific objectives of this study were to compare the differences between …

Influence Of Systematic Training On Morpho-Physiological And Motor Ability Profiles Of Indian Young Female Rowers, Kayakers And Canoers, Tamoghni Manna, Snehunsu Adhikari, Alak Kumar Syamal

International Journal of Exercise Science

International Journal of Exercise Science 16(6): 744-755, 2023. Our study was carried on junior female athletes (22 rowers, 11 kayakers and 7 canoers) adopting systemic training to explore the possible training manipulation that can be implicated in these three kinds of water sports, might be in a different way. Several morpho-physiological parameters and motor ability profiles were measured by standard methods. Accordingly, body weight (kg), performing time of 2.4 km run (sec), 6×10 meters shuttle run/agility (sec) of female rowers were reduced progressively and significantly from Preparatory Period (PP1) to General Practice Period (GPP) i.e., from (59.41±4.84) to (52.23±5.34), (773.04±92.64) …

Psychological And Physiological Responses Across Six Weeks Of Hiit And Mict In Previously Inactive Young Adults, Emily R. Dunston, Katrina Taylor

International Journal of Exercise Science

International Journal of Exercise Science 16(5): 756-769, 2023. High-intensity interval training (HIIT) is suggested as a public health strategy to increase engagement in, and adherence to, physical activity. However, debate exists regarding the efficacy in inactive individuals. PURPOSE: To determine the physiological and psychological responses to three weeks of supervised and three weeks of unsupervised HIIT or moderate-intensity continuous training (MICT) in previously inactive adults. METHODS: Young adults (n = 20; 21.4 ± 2.2 years; 13 females) were randomized to six weeks of HIIT or MICT. Pre- and post-testing included anthropometric measures, an incremental exercise test, and body composition. …

The Effects Of Hiit Versus Mict And Sedentary Controls On Blood Lipid Concentrations In Nondiabetic Overweight And Obese Young Adults: A Meta-Analysis., Christian P. Mccormick, Garrett Mamikunian, David B. Thorp

International Journal of Exercise Science

International Journal of Exercise Science 16(3): 791-813, 2023. With rates of obesity and dyslipidemia rising among young adults, this meta-analysis aimed to compare the effects of high-intensity interval training (HIIT) versus moderate-intensity continuous training (MICT) and sedentary controls (CON) on low-density lipoprotein (LDL), high-density lipoprotein (HDL), triglyceride (TG), and total cholesterol (TC) in nondiabetic overweight and obese young adults to determine if HIIT or MICT is more efficacious in improving dyslipidemia. Studies included in the analysis had to be randomized controlled trials or quasi-experimental studies, comparing the effects of HIIT versus MICT or CON on at least three variables of …

Evaluating The Effects Of Social Media On The Mental Health Of Dlsu-Is - Laguna Campus Grade 12 Students, Lara Althea Lunod Nunag, Mico Emison Cayago Bañadera, Kay Marianne Vicquierra Paguntalan, Julliana Marie Bernedo Rut

DLSU Senior High School Research Congress

Social media has become an integral part of the twenty-first century. Today, adolescents are one of the fastest-growing age groups for social media usage. Previous research has shown that mental health is one of the factors that is affected by social media usage. Mental health is an individual’s state of mind which includes their social, psychological, and emotional well-being. This study aims to determine whether there is a correlation between social media usage and the mental health of Senior High School (SHS) students at De La Salle University - Integrated School (DLSU-IS) Laguna campus. An online survey was administered containing …

Investigating The Physico-Chemical And Sensory Properties Of Coffee Fractions From The 4:6 Method, Nathaniel Angelo P. Arellano, Alyanna Claire L. Mejias, Janelle Nicolaine D. Sasi, Mariel M. Tamondong, Emmanuel V. Garcia

DLSU Senior High School Research Congress

As coffee becomes the favored beverage by many, brewing processes have become popular. After winning the 2016 World Brewers Cup, Tetsu Kasuya’s 4:6 method has since been dominant. This study aimed to characterize the 4:6 method's fractions by investigating increments where changes in the brew become the most observable. The study determined that the pH level was at its greatest value in the first 40%, followed by an increasing trendline. Secondly, the TDS displayed the greatest value at around 40%, followed by a decreasing trendline. Given this, solids and acids dictating the coffee's acidity are dissolved earlier, while the 60% …

Evaluating The Effects Of Social Media On The Mental Health Of Dlsu-Is - Laguna Campus Grade 12 Students, Mico Emison C. Bañadera, Lara Althea L. Nunag, Kay Marianne V. Paguntalan, Julliana Marie B. Rut

DLSU Senior High School Research Congress

Social media has become an integral part of the twenty-first century. Today, adolescents are one of the fastest-growing age groups for social media usage. Previous research has shown that mental health is one of the factors that is affected by the use of social media. Mental health is an individual’s state of mind which includes their social, psychological, and emotional well-being. The purpose of this study is to determine if there is no difference in the mental health among social media users of Senior High School (SHS) students at De La Salle University - Integrated School (DLSU-IS) Laguna campus between …

Determining The Occurrence And Effect Of Dysmenorrhea On The Productivity Of Ids 121 & 122 Female Dlsu-Is Students Manila, Linette Belle L.T. Ang, Yzabelle C. Bautista, Suzandra Kirstin Mikaela C. Chan, Jemina Gwyneth D. Pedres, Valerie A. Siy

DLSU Senior High School Research Congress

Dysmenorrhea, the abdominal pain experienced during menstruation, has been prevalent in a vast percentage of women across the globe. Numerous studies stated that dysmenorrhea has taken a toll on the productivity of women, and further develops into a public health problem that negatively affects the economy. Inspired by this, the study aimed to determine the effect of the different intensity levels of dysmenorrhea and various applications of coping mechanisms in the productivity level of female IDs 121 and 122 students by means of distributing an online survey. The study gathered a sample of 78 respondents. Their responses were used for …

From Books To Binges: Academic Workload Stress, Emotional Eating Assessment, And Body Mass Index Among University Students In Metro Manila, Catrina Leyla Quizon La Madrid, Alexa Marie I. Aguirre

DLSU Senior High School Research Congress

Online learning has become the new standard in the educational system due to the COVID-19 pandemic. This change has resulted in various drawbacks, such as an increased workload and a feeling of isolation, which are stress factors among students. Furthermore, students are inclined to consume more through emotional eating due to increased stress from their academic workloads, leading to an increased Body Mass Index (BMI). This study describes the degree of emotional eating among university students during the pandemic. It investigates the influence of academic workload stress on emotional eating and, in turn, influences their body mass index. This study …

The Irregularity Of Menstruation Among Adolescents: A Sequential Mixed Methods Study With Regards To Stress And Sedentary Behavior, Amanda Louise L. Abante, Yhesa Camille O. Lorca, Zophiel Faye B. Lumabi, Kimberleigh D, Metrio

DLSU Senior High School Research Congress

There has been a lack of research on the irregular menstruation of female adolescents in the Philippines. However, few studies still exist on middle-aged women and young adults in urban areas. It was also stated that in the Philippines, menstrual disorders were the third most commonly reported gynecological morbidity (Campbell & Harlow, 2000). Thus, the study aims to research the mental stress and physical sedentary behavior concerning irregular menstruation of female adolescent Filipinos. Explanatory sequential mixed methods were used in the study, wherein the qualitative data expounded the quantitative. Non-probability sampling: Convenience sampling was used. The Google forms were disseminated …

(Anti)Poverty Measures Exposed, Francine J. Lipman

Florida Tax Review

Few economic indicators have more salience and pervasive financial impact on everyday lives in the United States than poverty measures. Nevertheless, policymakers, researchers, advocates, and legislators generally do not understand the details of poverty measure mechanics. These detailed mechanics shape and reshape poverty measures and the too often uninformed responses and remedies. This Article will build a bridge from personal portraits of families living in poverty to the resource allocations that failed them by exposing the specific detailed mechanics underlying the Census Bureau’s official (OPM) and supplemental poverty measures (SPM). Too often, when we confront the problem of poverty, the …

Arnold-Chiari Malformation-I Borderline Personality Disorder, Aric Huber, Matthew Driben, Eduardo Espiridion

Transformative Medicine

Introduction:
Arnold-Chiari Malformation I (AM-I) is a congenital anomaly that manifests with cerebellar dysfunction. There is a displacement of cerebellar tonsils into the foramen magnum. Several mood disorders, personality disorders, and intellectual disabilities are associated with AM-I. Borderline personality disorder (BPD) is characterized by symptoms of mood lability, impulsivity, extreme efforts of abandonment, splitting and dysfunctional relationships.

Case Description:
The patient is an early aged adult with a past medical history of AM-I, hypothyroidism, Wolff-Parkinson-White syndrome, and diabetes mellitus type II. The patient was admitted to the hospital after ingesting foreign bodies. He/she presented with mood lability, sad mood, anhedonia, …

Commentary On The Obesity Epidemic: A Family Medicine Perspective, Mediha B. Chaudhry, Katherine Goth

Transformative Medicine

No abstract provided.

Dietary Inclusion Of Kulitis (Amaranthus Viridis) To Enhance Laying Hens’ Egg Quality, Kian Matthew S. Del Mundo, Mike Luigi G. Mario, Kirsten Khyla C. Zarate

DLSU Senior High School Research Congress

Philippine poultry manufacturers choose selectively bred hens over native hens in commercial egg-laying operations due to the native hens’ lower egg production and lower egg weights. As such, it was decided to ascertain whether including 15% Kulitis (Amaranthus viridis) leaves in the hen diet can enhance egg quality, specifically overall egg weight, yolk color, and eggshell thickness. Two 26-week-old Darag hens weighing 1 kg were selected and fed standard feed (untreated hen) and Kulitis-infused feed pellets (treated hen) for 21 days. Water was given ad libitum. The first five eggs laid by each hen were collected and evaluated for overall …

Isolation, Characterization, And Identification Of The Most Common Bacterial Isolates From Second-Hand Clothes In Selected Ukay-Ukay Stores In Dasmarinas, Cavite, Ma. Zuzynne D. Ocampo, Lou Adrian D. Aquino Jr., Mariel Antonnia R. Aquino, Rinangem P. Buenavente, Nikka Alyzel M. Tropel

DLSU Senior High School Research Congress

Throughout history, clothing's significance has evolved from a basic survival necessity to becoming an integral part of human social and cultural identity. Their sanitation significantly influences the health and condition of humans wearing these garments. For instance, clothes can serve as a reservoir for bacteria, fungi, and other germs that benefit or harm human health. Recent studies reveal the complex relationship between clothing and the microorganisms in our surroundings. This study aims to isolate, identify, and characterize the most common bacteria found in Second-Hand Clothing (SHCs) in Dasmarinas Cavite from three cotton shirts sampled from each of three random ukay-ukay …

Examination Of Domestic Tourists’ Awareness And Attitude Towards Halal Food According To Demographic Variable: The Gaziantep Example, Adem Ademoglu

Journal of Mediterranean Tourism Research

Religion and belief which are among the intangible cultural elements play an essential role in shaping consumer behavior. Among these behaviors, individuals’ increasing religious sensitivity within the context of eating and drinking in particular necessitates the food they consume to be in concordance with religious values. From this point of view, it is envisioned that individuals’ demographic characteristics will cause differences in food consumption demands in accordance with their religiousness values. The purpose of this study is to determine the role of demographic variables in the awareness towards halal food consumption and attitude towards halal food. Moreover, another purpose of …

June 27, 2023 Ereporter, University Of Alabama At Birmingham

eReporter (campus newsletter)

No abstract provided.

Targeting The Vulnerabilities Of Oncogene Activation, Christina Huang, Jack L. Arbiser

Student Papers, Posters & Projects

No abstract provided.

Primary Care Provider Density And Social Ecological Factors Related To County-Level Diabetes Prevalence In The United States, Robert Alan Kemsley

Theses and Dissertations

Diabetes is a critical public health concern with considerable financial and personal costs in the United States. Research has identified several interventions available to primary care providers to prevent diabetes. These interventions may prevent diabetes by influencing personal, community, and public health policy factors. These factors are key components of the social ecological model, which examines the influence of diverse social influences on health. Therefore, the purpose of this study was to determine the univariate relationship between PCP density and diabetes prevalence, as well as the multivariate relationship between PCP density and diabetes prevalence with physical inactivity prevalence, obesity prevalence, …

Randomized Intervention And Outpatient Follow-Up Lowers 30-D Readmissions For Patients With Hepatic Encephalopathy, Decompensated Cirrhosis, Antoinette Pusateri, Kevin Litzenberg, Claire Griffiths, Caitlin Hayes, Bipul Gnyawali, Michelle Manious, Sean G Kelly, Lanla F Conteh, Sajid Jalil, Haikady N Nagaraja, Khalid Mumtaz

Faculty, Staff and Student Publications

BACKGROUND: We previously reported national 30-d readmission rates of 27% in patients with decompensated cirrhosis (DC).

AIM: To study prospective interventions to reduce early readmissions in DC at our tertiary center.

METHODS: Adults with DC admitted July 2019 to December 2020 were enrolled and randomized into the intervention (INT) or standard of care (SOC) arms. Weekly phone calls for a month were completed. In the INT arm, case managers ensured outpatient follow-up, paracentesis, and medication compliance. Thirty-day readmission rates and reasons were compared.

RESULTS: Calculated sample size was not achieved due to coronavirus disease 2019; 240 patients were randomized into …

Spatial Single-Cell Sequencing Of Meiosis I Arrested Oocytes Indicates Acquisition Of Maternal Transcripts From The Soma, Kenneth A Trimmer, Peisen Zhao, Jacob Seemann, Shin-Yu Chen, Sudip Mondal, Adela Ben-Yakar, Swathi Arur

Faculty, Staff and Student Publications

Maternal RNAs are stored from minutes to decades in oocytes throughout meiosis I arrest in a transcriptionally quiescent state. Recent reports, however, propose a role for nascent transcription in arrested oocytes. Whether arrested oocytes launch nascent transcription in response to environmental or hormonal signals while maintaining the meiosis I arrest remains undetermined. We test this by integrating single-cell RNA sequencing, RNA velocity, and RNA fluorescence in situ hybridization on C. elegans meiosis I arrested oocytes. We identify transcripts that increase as the arrested meiosis I oocyte ages, but rule out extracellular signaling through ERK MAPK and nascent transcription as a …

Wildlife Ecological Risk Assessment In The 21st Century: Promising Technologies To Assess Toxicological Effects, Barnett A. Rattner, Thomas G. Bean, Val R. Beasley, Philippe Berny, Karen M. Eisenreich, John E. Elliott, Margaret L. Eng, Phyllis C. Fuchsman, Mason D. King, Rafael Mateo, Carolyn B. Meyer, Jason M. O'Brien, Christopher J. Salice

United States Geological Survey: Staff Publications

Despite advances in toxicity testing and the development of new approach methodologies (NAMs) for hazard assessment, the ecological risk assessment (ERA) framework for terrestrial wildlife (i.e., air‐breathing amphibians, reptiles, birds, and mammals) has remained unchanged for decades. While survival, growth, and reproductive endpoints derived from whole-animal toxicity tests are central to hazard assessment, nonstandard measures of biological effects at multiple levels of biological organization (e.g., molecular, cellular, tissue, organ, organism, population, community, ecosystem) have the potential to enhance the relevance of prospective and retrospective wildlife ERAs. Other factors (e.g., indirect effects of contaminants on food supplies and infectious disease processes) …

High-Risk Fertility Behaviors: Impact On Child And Risks Of Maternal Mortality In Kenya, Mercy Chepkosgei Kiprop

Theses and Dissertations

Rapid population increase in Sub-Saharan Africa (SSA) over the last several decades and limited healthcare interventions have exacerbated child and maternal mortality. The maternal mortality ratio (deaths per 100,000 live births) in Sub-Saharan Africa accounts for at least 50 percent of maternal deaths globally. In 2020 alone, 5 million children under 5 years died in Kenya. Research also points out that, tragically, many of the mothers and children died of preventable or treatable conditions. Previous research has focused on biological or socioeconomic determinants of child mortality rather than their joint influences. In this study, we investigate the premise that all …