Digital Commons Network^™

Barriers And Facilitators Of Family Rules And Routines During Pediatric Cancer Treatment., Carolyn R. Bates, Isabella K. Pallotto, Rachel Moore, Lynne Covitz, Meredith Dreyer

Manuscripts, Articles, Book Chapters and Other Papers

OBJECTIVE: Pediatric nurses work closely with families of children with new cancer diagnoses and can provide essential supports to promote coping and adjustment. This cross-sectional qualitative study aimed to gather caregiver perspectives on barriers and facilitators to adaptive family functioning during the early phases of cancer treatment, with a focus on family rules and routines.

METHODS: Caregivers (N = 44) of a child diagnosed with cancer and receiving active treatment completed a semi-structured interview about their engagement in family rules and routines. Time since diagnosis was abstracted from the medical record. A multi-pass inductive coding strategy was utilized to extract …

Evaluation Of Health And Economic Effects Of United States School Meal Standards Consistent With The 2020–2025 Dietary Guidelines For Americans, Lu Wang, Juliana Cohen, Meghan Maroney, Fredrick Cudhea, Alla Hill, Colin Schwartz, Peter Lurie, Dariush Mozaffarian

Health Sciences Faculty Publications

Background: The current school meal nutrition standards, established in 2010, are not fully aligned with the 2020-2025 Dietary Guideline for Americans (DGA). This study evaluates the potential short-term and long-term health and economic benefits of strengthening the school meal standards on added sugars, sodium, and whole grains to be aligned with current guidelines.

Methods: We used comparative risk assessment frameworks based on nationally representative data incorporating current demographics, dietary habits, and risk factors of United States children aged 5-18 y from 3 cycles of the National Health and Nutrition Examination Survey (2013-2018). To estimate short-term impact, the model incorporated estimated …

Sex-Dependent Effects Of Intestinal Microbiome Manipulation In A Mouse Model Of Alzheimer’S Disease, Harpreet Kaur, Suba Nookala, Surjeet Singh, Santhosh Mukundan, Kumi Nagamoto-Combs, Colin K. Combs

Biomedical Sciences Faculty Publications

Mechanisms linking intestinal bacteria and neurodegenerative diseases such as Alzheimer’s disease (AD) are still unclear. We hypothesized that intestinal dysbiosis might potentiate AD, and manipulating the microbiome to promote intestinal eubiosis and immune homeostasis may improve AD-related brain changes. This study assessed sex differences in the effects of oral probiotic, antibiotics, and synbiotic treatments in the AppNL-G-F mouse model of AD. The fecal microbiome demonstrated significant correlations between bacterial genera in AppNL-G-F mice and Aβ plaque load, gliosis, and memory performance. Female and not male AppNL-G-F mice fed probiotic but not synbiotic exhibited a decrease in Aβ plaques, microgliosis, brain …

Hla-Ii Alleles Influence Physical And Behavioral Responses To A Whey Allergen In A Transgenic Mouse Model Of Cow's Milk Allergy, Danielle L. Germundson, Suba Nookala, Nicholas A. Smith, Yassmine Warda, Kumi Nagamoto-Combs

Biomedical Sciences Faculty Publications

The symptoms of food allergies vary significantly between individuals, likely due to genetic determinants. In humans, allergy development is initiated by antigen-presenting cells via class II human leukocyte antigen (HLA-II). The HLA-II gene is highly polymorphic, and its allelic variance is thought to influence the susceptibility of individuals to a particular allergen. However, whether antigen presentation by different HLA-II variants contributes to symptom variation is not clear. We hypothesized that HLA-II allelic variance affects symptom phenotypes, including immediate physical reactions and delayed behavioral changes, in individuals with food hypersensitivity. To test our hypothesis, male and female mice of three transgenic …

Sleep, Body Dissatisfaction, And Eating Among Adolescents, Megan White

Loma Linda University Electronic Theses, Dissertations & Projects

Sleep difficulties in adolescence have been linked to greater impulsivity, negative affect, propensity to interpret neutral stimuli as negative, and higher rates of anxiety and depressive symptomatology (Van Dyk, 2016). However, minimal research has looked at the relationship among sleep difficulties, emotional eating, and body dissatisfaction within this population. Therefore, the aim of the current study was to explore the relationship among sleep difficulties, emotional eating, and body dissatisfaction among adolescents aged 12-18 years. Specifically, the current study stands to 1) confirm the relationship between emotional eating and body dissatisfaction; 2) test if sleep difficulties are related to emotional eating; …

Replacing Ground Corn With Liquid Molasses In Diets Of Jersey Cows Fed Red Clover Baleage: Effects On Milk Production, Nitrogen Efficiency, Energy Utilization, And Enteric Methane Emissions, Adam Lee Konopka

Master's Theses and Capstones

Molasses is a food byproduct rich in sucrose commonly added to the diets of cattle which has been reported to enhance milk production, promote rumen microbial growth, and increase digestibility of nutrients. Variable results obtained when partially replacing starch sources with molasses have led to an increased interest in the dietary conditions under which molasses could optimize the production of dairy cows. We aimed to investigate the effect of partially replacing ground corn with sugarcane liquid molasses on dry matter intake, milk yield and composition, enteric methane emissions, and N utilization in lactating Jersey cows fed red clover baleage. Eighteen …

A Biological Lens On Food Deserts [Biology], Claudette Davis

Open Educational Resources

SCB101 is a non-major biology course. In Fall 2022, the course was designated as an Experiential Learning-LaGuardia Humanitarian Initiative (LHI) course in CUNYFirst. LHI is LaGuardia's experiential learning program that helps students to critically reflect on global issues and develop sustainable solutions in partnership with local and global organizations. For the 2022-2023 academic year, LHI focused on two United Nations Sustainable Development Goals (UNSDG): Goal 2 and Goal 10. UNSDG 2 aims to end hunger, achieve food security, improve nutrition, and promote sustainable agriculture. UNSDG 10 addresses reducing inequality both within and among countries. Thus, I developed an assignment to …

Rights And Remedies: Rental Housing For Low-Income Households In The United States, David Ray Papke, Mary Elise Papke

Marquette Benefits and Social Welfare Law Review

The state of rental housing for low-income households in the United States is deplorable. Unaffordable, unsanitary, and insecure, this housing violates the internationally recognized right of housing. While the United States has never formally recognized that right, the right guarantees not only a roof overhead but also affordability, habitability, and security of tenure. Policies and programs seeking to remedy the problems in rental housing might consciously address these aspects of rental housing. Policies and programs of this sort will not be enough to eliminate all problems, but they would alleviate a matter of great embarrassment, namely, the most affluent country …

A Nuanced Examination Of Primate Capture And Consumption And Human Socio-Economic Well-Being In Kirindy Mitea National Park, Madagascar, Domenic Romanello, Katharine E.T. Thompson, Cortni Borgerson, Jeanne Mathilde Randriamanetsy, Niaina Nirina Mahefa Andriamavosoloarisoa, Mamy Yves Andrianantenaina, Théofrico Alexander Razafindrahasy, Claire Surkis, Patricia C. Wright, Katheryn C. Twiss, Rebecca J. Lewis

Department of Anthropology Faculty Scholarship and Creative Works

The futures of human and nonhuman primates are closely tied in protected areas. Understanding this interconnectedness is especially urgent in Madagascar, one of the world’s most impoverished biodiversity hotspots. Yet, no study has evaluated the relationship between poverty and lemur hunting and consumption using a composite poverty metric that includes health, education, and living standards. To address this gap, and to inform primate conservation practice and policy, we administered annual surveys to 81 households over six consecutive months (September 2018 to March 2019) in a village on the border of Kirindy Mitea National Park, Madagascar. We observed extreme deprivation scores …

Antibiotic-Induced Gut Dysbiosis And Cognitive, Emotional, And Behavioral Changes In Rodents: A Systematic Review And Meta-Analysis, Shivdeep S. Hayer, Soonjo Hwang, Jonathan B. Clayton

Department of Nutrition and Health Sciences: Faculty Publications

There are previous epidemiological studies reporting associations between antibiotic use and psychiatric symptoms. Antibiotic-induced gut dysbiosis and alteration of microbiota-gut-brain axis communication has been proposed to play a role in this association. In this systematic review and meta-analysis, we reviewed published articles that have presented results on changes in cognition, emotion, and behavior in rodents (rats and mice) after antibiotic-induced gut dysbiosis. We searched three databases—PubMed, Web of Science, and SCOPUS to identify such articles using dedicated search strings and extracted data from 48 articles. Increase in anxiety and depression-like behavior was reported in 32.7 and 40.7 percent of the …

The Dangers Of Staphylococcus Aureus And Antimicrobial Resistance, Madison Pines

Graduate Student Dissertations, Theses, Capstones, and Portfolios

Methicillin-resistant Staphylococcus aureus (MRSA) is the etiological agent responsible for many problematic infections. The signs and symptoms of an infection caused by MRSA differ based on the route of transmission and type of infection. Staphylococcus aureus can secrete toxins that act as virulence factors and aid host invasion. Obesity, old age, being a health care worker, playing contact sports, living in a crowded place, hospitalization, recent antibiotic use, and HIV patients are more at risk of developing an infection caused by MRSA. An abundance of factors has contributed to antimicrobial resistance, like misuse of antibiotics in clinical and agricultural settings …

Trauma Mediating The Severity Of Depressive Symptoms In Veterans With Ptsd, Meghan Curtin

Dissertations

Trauma serves as a risk factor for developing both posttraumatic stress disorder (PTSD) and depression. The purpose of this study was to examine trauma type as a mediator in the relationship between gender and severity of depressive symptoms among veterans with PTSD. The literature shows trauma type plays a role in developing PTSD and depressive symptoms. The first hypothesis was that female veterans who met the diagnostic criteria for PTSD would report higher levels of depressive symptoms than their male counterparts. The second hypothesis was that this gender difference would be partly mediated by levels of interpersonal trauma experience. Self-report …

Recap Report: Girls Deliver Pre-Conference On Adolescent Girls At The Women Deliver 2023 Conference, Girl Center

Adolescents and Young People

The Girls Deliver: Pre-Conference on Adolescent Girls was held on July 16, 2023 in Kigali Rwanda to kick off the Women Deliver 2023 Conference. Girls Deliver was led by the Population Council’s Girl Innovation, Research, and Learning Center (GIRL Center) and co-hosted by AFIDEP, Amplify Girls, Baobab Research Programme Consortium, Children’s Investment Fund Foundation, Coalition for Adolescent Girls, Exemplars in Global Health, FP2030, Girl Effect, Girls First Fund, Hilton Foundation, NDI, Plan International, PMNCH, Purposeful, Together for Girls, UNICEF, Women Deliver, and The World Bank Africa Gender Innovation Lab.

This recap report presents an overview of Girls Deliver, a summary …

Hospitalizations Among Adults With Ckd In Public Renal Specialty Practices: A Retrospective Study From Queensland, Australia, Vishal Diwan, Wendy E Hoy, Zaimin Wang, Jianzhen Zhang, Anne Cameron, Sree K Venuthurupalli, Robert G Fassett, Samuel Chan, Helen G Healy, Ken-Soon Tan, Richard Baer, Andrew J Mallett, Nicholas Gray, Murty Mantha, Roy Cherian, Clyson Mutatiri, Krishan Madhan, George Kan, Geoffrey Mitchell, Shahadat Hossain, Danielle Wu, Thin Han, Adrian Kark, Thomas Titus, Dwarakanatan Ranganathan, Ann Bonner, Sridevi Govindarajulu, Nhmrc Ckd.Cre And The Ckd.Qld Collaborative

Faculty, Staff and Student Publications

RATIONALE & OBJECTIVE: Little is known about hospital admissions in nondialysis patients with chronic kidney disease (CKD) before death or starting kidney replacement therapy (KRT).

STUDY DESIGN: Retrospective observational cohort study.

SETTING & PARTICIPANTS: Hospitalizations among 7,201 patients with CKD from 10 public renal clinics in Queensland (QLD), enrolled in the CKD.QLD registry starting in May 2011, were followed for 25,496.34 person-years until they started receiving KRT or died, or until June 30, 2018.

PREDICTORS: Demographic and clinical characteristics of patients with CKD.

OUTCOMES: Hospital admissions.

ANALYTICAL APPROACH: We evaluated the association of demographic and clinical features with hospitalizations, length …

Interleukin-10 In Cancer Immunotherapy: From Bench To Bedside, Mohamad Adham Salkeni, Aung Naing

Faculty, Staff and Student Publications

Interleukin (IL)-10 was one of the first cytokines to be recognized. However, its functionality in promoting antitumor immunity was described more recently. Context- and concentration-dependent biological effects are the hallmarks of the pleiotropic role of IL-10. Despite reducing tumor-promoting inflammation, IL-10 may have a role in rejuvenating exhausted tumor-resident T cells. Contrary to the assumption that IL-10 produces an immunosuppressive tumor microenvironment (TME), it promotes activation of tumor-resident CD8+ T cells, which aids tumor rejection. Emerging data from published early-Phase trials have shown mixed results in different tumor types. In this review, we summarize the biological effects of IL-10 and …

Early Initiation Of B-Vitamin Supplementation May Reduce Symptoms And Explain Intrafamilial Variability: Insights From Two Sibling Pairs From The Tango2 Natural History Study, Christina Y Miyake, Saad A Ehsan, Lilei Zhang, Samuel J Mackenzie, Mahshid S Azamian, Daryl A Scott, Andres Hernandez-Garcia, Seema R Lalani

Faculty, Staff and Students Publications

TANGO2-deficiency disorder (TDD) is an autosomal recessive condition arising from pathogenic biallelic variants in the TANGO2 gene. TDD is characterized by symptoms typically beginning in late infancy including delayed developmental milestones, cognitive impairment, dysarthria, expressive language deficits, and gait abnormalities. There is wide phenotypic variability where some are severely affected while others have mild symptoms. This variability has been documented even among sibling pairs who share the same genotype, but reasons for this variability have not been well understood. Emerging data suggest a potential link between B-complex or multivitamin supplementation and decreased metabolic crises in TDD. In this report, we …

Maternal Metabolism Influences Neural Tube Closure, Rachel A Keuls, Richard H Finnell, Ronald J Parchem

Faculty, Staff and Students Publications

Changes in maternal nutrient availability due to diet or disease significantly increase the risk of neural tube defects (NTDs). Because the incidence of metabolic disease continues to rise, it is urgent that we better understand how altered maternal nutrient levels can influence embryonic neural tube development. Furthermore, primary neurulation occurs before placental function during a period of histiotrophic nutrient exchange. In this review we detail how maternal metabolites are transported by the yolk sac to the developing embryo. We discuss recent advances in understanding how altered maternal levels of essential nutrients disrupt development of the neuroepithelium, and identify points of …

Sports Drinks Effect On Salivary Volume And Ph In Children After Exercise: A Randomized Clinical Study, Matina V. Angelopoulou, Alicia Malak-Santaga, Andreas Agouropoulos, Cesar D. Gonzalez

School of Dentistry Faculty Research and Publications

BACKGROUND: The aim of this study was to examine the sports’ related oral health behavior and the effect of sports drinks on the salivary volume and acidity of 6 to 14 years old children.

METHODS: Sixty-eight children with a median age of 8 years old from Waterford Tennis Association camp participated in the study. Each child was randomly assigned to either the control group that consumed water or the experimental group that consumed a sports drink. Salivary volume and acidity were measured for all groups before exercise, right after exercise and after consuming the rehydrating agent. Salivary volume was measured …

Unexpected Drug-Induced Liver Injury Associated With Menofit: A Synbiotic Menopause Supplement, Apaar Dadlani, Azubuogu Anudu, E Celia Marginean

Faculty, Staff and Students Publications

MenoFit is a widely available over-the-counter synbiotic supplement, which is marketed for use in relieving menopausal symptoms. So far, there is no published data on liver injury because of its use. We present the first reported case of MenoFit-induced liver injury in a patient who presented with 1 week of jaundice and abnormal liver biochemical tests in the absence of other risk factors and negative comprehensive workup for known etiologies of liver disease.

Exome Sequencing Implicates Dgkz , Esrra , And Gxylt1 For Modulating Granuloma Formation In Crohn Disease, R Alan Harris, Allyson H Bush, Todd N Eagar, Justin Qian, Michael P Greenwood, Antone R Opekun, Robert Baldassano, Stephen L Guthery, Joshua D Noe, Anthony Otley, Joel R Rosh, Subra Kugathasan, Richard Kellermayer

Faculty, Staff and Students Publications

Non-caseating granulomas may indicate a more aggressive phenotype of Crohn disease (CD). Genetic associations of granulomatous CD (GCD) may help elucidate disease pathogenesis. Whole-exome sequencing was performed on peripheral blood-derived DNA from 17 pediatric patients with GCD and 19 with non-GCD (NGCD), and from an independent validation cohort of 44 GCD and 19 NGCD cases. PLINK (a tool set for whole-genome association and population-based linkage analyses) analysis was used to identify single nucleotide polymorphisms (SNPs) differentiating between groups, and subgroup allele frequencies were also compared to a public genomic database (gnomAD). The Combined Annotation Dependent Depletion scoring tool was used …

Uae Women’S Knowledge And Attitudes Towards Physical Activity During Pregnancy, Sharifa Alblooshi, Rafiq Hijazi, Lynne Kennedy, Ala Al Rajabi

All Works

The benefits of being physically active during pregnancy are widely acknowledged. It is important for the prevention of chronic diseases and the promotion of good health for mothers and children. However, physical activity by women in the UAE is notoriously low and reduced further during pregnancy. The same can be said regarding research about the knowledge and understanding of the benefits and risks associated with exercise as a predictor of behavior. We aimed to assess knowledge and attitudes towards physical activity during pregnancy amongst Emirati women. A cross-sectional digital survey was designed to assess knowledge and attitudes and distributed to …

Associations Between Birth Weight And Adult Sleep Characteristics: A Cross-Sectional Analysis From The Uaehfs, Nirmin F. Juber, Abdishakur Abdulle, Amar Ahmad, Andrea Leinberger-Jabari, Ayesha S.Al Dhaheri, Fatma Al-Maskari, Fatme Alanouti, Mohammad Al-Houqani, Mohammed Hag Ali, Omar El-Shahawy, Scott Sherman, Syed M. Shah, Tom Loney, Youssef Idaghdour, Raghib Ali

All Works

Abnormal birth weight, particularly low birth weight (LBW), is known to have long-term adverse health consequences in adulthood, with disrupted sleep being suggested as a mediator or modifier of this link. We thus aimed to assess the associations between birth weight and self-reported adult sleep characteristics: sleep duration, difficulty waking up in the morning, daily nap frequency, sleep problems at night, snoring, daytime tiredness or sleepiness, and ever-stop breathing during sleep. This cross-sectional analysis used the United Arab Emirates Healthy Future Study data collected from February 2016 to March 2023 involving 2124 Emiratis aged 18–61 years. We performed a Poisson …

Supervisory Impact On Counselor-In-Training Wellness, Erin Brumfield Grima

Dissertations

Counselors being able to engage in self-care practices to establish and maintain their wellness is a well-documented need. The risks of neglecting self-care are also well documented, yet counselors struggle to engage in consistent self-care practices (Baker & Gabriel, 2021; Posluns & Gall, 2020). When demand for counselors is constant (Bureau of Labor Statistics, U.S. Department of Labor, 2020) an examination of how to impact counselor wellness through supervision discussion of self-care is needed. The purpose of the study was to examine supervision discussion of self-care, support of mastery of counselors-in-training’s emotions and any resulting impact on counselor wellness. Data …

Tennessee Farm Bureau News - September 2023, Tennessee Farm Bureau Federation

Tennessee Farm Bureau News

No abstract provided.

An Examination Of The Relationships Between The Neighborhood Social Environment, Adiposity, And Cardiometabolic Disease Risk In Adolescence: A Cross-Sectional Study, Kara D. Denstel, Robbie A. Beyl, Denise M. Danos, Maura M. Kepper, Amanda E. Staiano, Katherine T. Theall, Tung Sung Tseng, Stephanie T. Broyles

School of Public Health Faculty Publications

Background: Disadvantaged neighborhood environments are a source of chronic stress which undermines optimal adolescent health. This study investigated relationships between the neighborhood social environment, specifically, chronic stress exposures, adiposity, and cardiometabolic disease risk factors among 288 Louisiana adolescents aged 10 to 16 years. Methods: This cross-sectional study utilized baseline data from the Translational Investigation of Growth and Everyday Routines in Kids (TIGER Kids) study. Adolescent data were obtained using self-reported questionnaires (demographics and perceived neighborhood disorder), anthropometry, body imaging, and a blood draw while objective neighborhood data for the concentrated disadvantage index were acquired from the 2016 American Community Survey …

Absorbance Measurements From Normal-Hearing Ears In The National Health And Nutrition Examination Survey, 2015–2016 And 2017–2020, Jiayi Sun, Nicholas J. Horton, Susan E. Voss

Engineering: Faculty Publications

Objective: To summarize absorbance and impedance angles from normal-hearing ears within the 2015–2016 and 2017–2020 US National Health and Nutrition Examination Surveys (NHANES).

Design: Two publicly available NHANES datasets were analyzed. Ears meeting criteria for normal hearing and valid absorbance and impedance angle measurements were identified. Measurements were summarized via descriptive statistics within categories of age cohort, race/ethnicity cohort, sex (male, female), and ear (left, right).

Results: A total of 7029 ears from 4150 subjects, ages 6 to 80 years, met inclusion criteria. Differences between subgroups within all categories (age, race/ethnicity, sex, and ear) were fractions of the sample SDs. …

Improving Primary Care Provider Prediabetes Patient Education Through Use Of An Education Tool, Larry Mcconnell Ii, Elizabeth Richards, Julian Gallegos, Marcella Tashijian-Gibbs

School of Nursing Faculty Publications

Current research findings suggest that improving provider education and utilizing communication guidelines can positively impact patient outcomes. This study used a series of three surveys and a focus group to examine if primary care provider’s knowledge, confidence, and practice regarding prediabetes patient education can be improved by utilizing the Ready and Able prediabetes lifestyle modification education tool. Study results found that the Ready and Able conversation guide was well received, had a positive impact on providers knowledge and confidence, and addressed barriers to delivering patient education.

Factors Affecting The Use Of Vestibular/Balance Screening Measures In Audiologists And Physical Therapists In Patients Reporting Dizziness, Alexandria W. Greene, Ashley G. Flagge, Nicholas S. Stanley

Ashley Flagge Publications

Purpose: Vestibular/balance screeners can improve the efficiency of the diagnostic process. Despite prior literature illustrating the importance of screeners, research suggests that many professionals do not utilize screening protocols. Methods: Thirty-two audiologists and thirty-four physical therapists completed an electronic survey with questions regarding the use of screeners and the referral process. The survey examined variables surrounding the use of vestibular/balance screeners among audiologists and physical therapists, including frequency of use, commonly used screeners, and factors affecting the use or non-use of screeners. Results: Physical therapists utilized vestibular/balance screeners statistically more often and used a larger variety of screeners compared to …

Comparison Of The Effects Of Alpha Lipoic Acid And Dexpanthenol In An Experimental Tracheal Reconstruction Animal Model, Murat Kuru, Tamer Altınok, Bayram Metin, Hacı Hasan Esen

Saudi Medical Journal

Objectives: To investigate the positive effects of intraperitoneal administration of alpha-lipolic acid (ALA) and dexpanthenol (DXP) on wound healing after tracheal surgery in rats. Methods: The study was carried out at Necmettin Erbakan University, Konya, Turkey, from January 2014-2019. A total of 30 healthy and adult Sprague-Dawley type female rats were included in the study. For the experiment, rats were randomly divided into 3 groups: ALA group (n=10), DXP group (n=10), and control group (n=10). After trachea surgery, 100 mg/kg/day ALA was given to group ALA and 100 mg/kg/day intraperitoneal DXP to group DXP for 15 days, and the rats …

Association Between Body Mass Index And Hemoglobin A1c With Serum Prostate-Specific Antigen Level: A Retrospective Cohort Study, Wejdan A. Alhamdan, Thamer A. Alsulaiman, Razan I. Alsabti, Ola M. Abdulmowla, Somayh E. Elnaggar, Yaser Alendijani

Saudi Medical Journal

Objectives: To assess the association between body mass index (BMI) and hemoglobin A1c (HbA1c) with serum prostate-specific antigen (PSA) level. Methods: A retrospective cohort study was carried out at King Faisal Specialist Hospital and Research Centre in Riyadh, Saudi Arabia, from January 2016 to December 2021. Data were collected from the medical records of patients who visited the family medicine clinics, including demographics, smoking status, BMI value, index PSA level, testosterone level, digital rectal exam findings, prostate biopsy status, fasting blood glucose (FBG), HbA1c, diabetes duration, chronic comorbidities (namely, hypertension, dyslipidemia, or chronic kidney disease), and medication history. Results: The …