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The Personalized Acne Treatment Tool - Recommendations To Facilitate A Patient-Centered Approach To Acne Management From The Personalizing Acne: Consensus Of Experts, Alison M. Layton, Andrew Alexis, Hilary Baldwin, Vincenzo Bettoli, James Del Rosso, Thomas Dirschka, Brigitte Dréno, Linda F. Stein Gold, Julie Harper, Joo Yeon Ko, Khaled Al Nuaimi, Hazel H Oon, Murlidhar Rajagopalan, Marco Rocha, Jo-Ann See, Jonathan Weiss, Jerry Tan

Dermatology Articles

BACKGROUND: Acne, a commonly treated skin disease, requires patient-centered management due to its varying presentations, chronicity, and impact on health-related quality of life. Despite this, evidence-based clinical guidelines focus primarily on clinical severity of facial acne, omitting important patient- and disease-related factors, including ongoing management.

OBJECTIVES: To generate recommendations to support patient-centered acne management, which incorporate priority and prognostic factors beyond conventional clinical severity, traditionally defined by grading the appearance and extent of visible lesions.

METHODS: The Personalizing Acne: Consensus of Experts consisted of 17 dermatologists who used a modified Delphi approach to reach consensus on statements regarding patient- and …

Pulmonary & Critical Care Insider: Issue 2, Bharat Bajantri Md, Sarah Ellsworth Mls

Critical Care & Pulmonary

Pulmonary & Critical Care Insider Issue 2

Compiled by Bharat Bajantri, MD, and librarian Sarah Ellsworth, MLS for the clinicians of the Pulmonary and Critical Care team of Parkview.

The goal of this newsletter is to give a brief summary of the most pertinent articles to everyday practice and an attempt to keep up with literature as best as possible. Newsletters go out every 1-2 months.

Summaries/Topics in this issue:

• Spontaneous Breathing Trials
• Enteral feedings
• EFFORT Protein trial
• The NUTRIREA-3 trial
• Veno-venous extracorporeal carbon dioxide removal (vv-ECCO2 R)
• Acute hypoxemic respiratory failure (AHRF)
• Penicillin allergy
• PEN-FAST score
• Etomidate increases mortality …

Adolescent Hope And Optimism: A Scoping Review Of Measures And Their Psychometric Properties, Esther Chongwo, Ezra Too, Adam Mabrouk, Amina Abubakar

Institute for Human Development, East Africa

There is much research examining adolescent hope and optimism, but there is limited information on the available measures, particularly the most frequently used measures and their psychometric properties. We conducted a scoping review to: (1) identify measures of hope and optimism for use among adolescents; (2) determine the most frequently used measures of adolescent hope and optimism; (3) document the psychometric properties of the identified measures. We searched five bibliographic databases and Open Grey for relevant articles published from database inception to 03 May 2023. The search included the key terms ‘adolescents’, ‘optimism’, ‘hope’ and ‘measures’. We targeted adolescents aged …

Dousing The Flame: Reviewing The Mechanisms Of Inflammatory Programming During Stress-Induced Intrauterine Growth Restriction And The Potential For Ω-3 Polyunsaturated Fatty Acid Intervention, Melanie White, Dustin T. Yates

Department of Animal Science: Faculty Publications

Intrauterine growth restriction (IUGR) arises when maternal stressors coincide with peak placental development, leading to placental insufficiency. When the expanding nutrient demands of the growing fetus subsequently exceed the capacity of the stunted placenta, fetal hypoxemia and hypoglycemia result. Poor fetal nutrient status stimulates greater release of inflammatory cytokines and catecholamines, which in turn lead to thrifty growth and metabolic programming that benefits fetal survival but is maladaptive after birth. Specifically, some IUGR fetal tissues develop enriched expression of inflammatory cytokine receptors and other signaling cascade components, which increases inflammatory sensitivity even when circulating inflammatory cytokines are no longer elevated …

Differences In Internalized Weight Stigma And The Treatment Of Clients In Larger Bodies Among Mental Health And Medical Professionals, Alexis Dosal

Dissertations

Weight is a complex interaction of several factors, including genetics, environment, adverse childhood experiences, culture, physiology, and emotional circumstances (Hale, 2019). By solely considering the categories of food consumption and individual activity, the belief of personal responsibility and controllability is perpetuated, which may lead to intentional or unintentional harm within interpersonal interactions and throughout medical services (Nutter et al., 2020). Weight bias refers to “stereotypes, negative attitudes, and discriminatory behavior toward individuals with larger bodies” (Nutter et al., 2020). Weight bias can be displayed as discomfort around those in larger bodies, holding beliefs that fat people are lazy or unattractive, …

Renin As A Biomarker Of Acute Kidney Injury And Mortality In Children With Severe Malaria Or Sickle Cell Disease, Daniel Adan, Anthony Batte, Ruth Namazzi, Ivan Mufumba, Caroline Kazinga, Kagan Mellencamp, Caitlin Bond, Robert Opoka, Chandy John, Andrea Conroy

Paediatrics and Child Health, East Africa

Background: Globally, a very high percentage of acute kidney injury (AKI) occurs in low- and middle-income countries (LMICs) where late recognition contributes to increased mortality. There are challenges with using existing biomarkers of AKI in LMICs. Emerging evidence suggests renin may serve as a biomarker of kidney injury that can overcome limitations in creatinine-based diagnostics.

Methods: Two study populations in Uganda were assessed. Cohort #1 was a two-site, prospective cohort study enrolling 600 children with severe malaria (SM). Cohort #2 was a prospective cohort study enrolling 185 children with sickle cell disease (SCD) hospitalized with a vaso-occlusive crisis. Plasma or …

Serum Sulfur-Containing Amino Acids And Risk Of Maternal Gestational Diabetes And Adverse Growth Patterns In Offspring, Ninghua Li, Jing Li, Hui Wang, Yijuan Qiao, Weiqin Li, Ming Gao, Enqing Liu, Zhijie Yu, Gang Hu, Zhongze Fang, Junhong Leng, Xilin Yang

Population and Public Health Science Faculty Publications

Background: To estimate associations of sulfur-containing amino acids (SAAs) in the early trimester of pregnancy and gestational diabetes mellitus (GDM) and estimate associations of maternal SAAs with adverse growth patterns in offspring. Methods: We established a 1:1 matched case-control study (n = 486) from our cohort of pregnant women, and 401 children were followed up at ages 1 to 8 years. We conducted binary conditional logistic regression to estimate the risk associations of serum SAAs with GDM. Multinomial logistic regression was implemented to explore associations of maternal SAAs with adverse growth patterns in the offspring. Results: High serum methionine and …

New Frontiers In The Measurement Of Energy Metabolism, Alexandra Niclou, Philippe St-Martin, Leanne M. Redman, Audrey Bergouignan

Clinical Research Faculty Publications

This perspective highlights three key areas of current and future energy metabolism research: intergenerational health, climate change, and interplanetary exploration. We describe the recent advances in determining estimated energy requirements for a large subset of the general population using the gold standard method for free-living total daily energy expenditure estimates, the doubly labeled water method. The global rise in overweight and obesity demands particular attention to energy requirements in pregnancy and early life, as accumulating evidence contributes to our understanding of intergenerational health transmission and the potential for epigenetic programming in utero. We also acknowledge some gaps in necessary guidelines …

Field Evaluations Of The Cropmanage Decision Support Tool For Improving Irrigation And Nutrient Use Of Cool Season Vegetables In California, Michael Cahn, Richard Smith, Forrest Melton

AES Faculty Publications and Presentations

Vegetable growers on the central coast of California are under regulatory pressure to reduce nitrate loading to ground and surface water supplies. California also implemented legislation that limits agricultural pumping in regions such as the central coast where the aquifers have been over-extracted for crop irrigation. Growers could potentially use less N fertilizer, address water quality concerns, and conserve water by improving water management and matching nitrogen applications to the N uptake pattern of their crops. Two tools available to growers, the soil nitrate quick test (SNQT) and reference evapotranspiration (ETo) data have been previously shown to improve the management …

Experimented With Watercolor Painting (Summer 2023), Erin Cromeans

Staff Residencies

Erin Cromeans is the Associate Director of Strategic Initiatives and Outreach at the Institute of Child Nutrition.

Exercise-Induced Changes To The Fiber Type-Specific Redox State In Human Skeletal Muscle Are Associated With Aerobic Capacity, James Shadiow, Edwin R. Miranda, Ryan K. Perkins, Corey E. Mazo, Zhen Lin, Kendell N. Lewis, Jacob T. Mey, Thomas P.J. Solomon, Jacob M. Haus

Division of Basic Science Faculty Publications

The benefits of exercise involve skeletal muscle redox state alterations of nicotinamide adenine dinucleotide (NAD) and flavin adenine dinucleotide (FAD). We determined the fiber-specific effects of acute exercise on the skeletal muscle redox state in healthy adults. Muscle biopsies were obtained from 19 participants (11 M, 8 F; 26 ± 4 yr) at baseline (fasted) and 30 min and 3 h after treadmill exercise at 80% maximal oxygen consumption (V O2max). Muscle samples were probed for autofluorescence of NADH (excitation at 340-360 nm) and oxidized flavoproteins (Fp; excitation at 440-470 nm) and subsequently, fiber typed to quantify the redox signatures …

Guidelines For Parenteral Nutrition In Preterm Infants: The American Society For Parenteral And Enteral Nutrition, Daniel T. Robinson, Kara L. Calkins, Yimin Chen, M. Petrea Cober, Gustave H. Falciglia, David D. Church, Jacob Mey, Liam Mckeever, Timothy Sentongo

Division of Basic Science Faculty Publications

Background: Parenteral nutrition (PN) is prescribed for preterm infants until nutrition needs are met via the enteral route, but unanswered questions remain regarding PN best practices in this population. Methods: An interdisciplinary committee was assembled to answer 12 questions concerning the provision of PN to preterm infants. The Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) process was used. Questions addressed parenteral macronutrient doses, lipid injectable emulsion (ILE) composition, and clinically relevant outcomes, including PNALD, early childhood growth, and neurodevelopment. Preterm infants with congenital gastrointestinal disorders or infants already diagnosed with necrotizing enterocolitis or PN-associated liver disease (PNALD) at study …

Reduced Postabsorptive Interoception Of Nutrients In Obesity: Cause Or Consequence?, Hans Rudolf Berthoud

Division of Basic Science Faculty Publications

No abstract provided.

Initial Weight Loss And Early Intervention Adherence Predict Long-Term Weight Loss During The Promoting Successful Weight Loss In Primary Care In Louisiana Lifestyle Intervention, Christoph Höchsmann, Corby K. Martin, John W. Apolzan, James L. Dorling, Robert L. Newton, Kara D. Denstel, Emily F. Mire, William D. Johnson, Dachuan Zhang, Connie L. Arnold, Terry C. Davis, Vivian Fonseca, Tina K. Thethi, Carl J. Lavie, Benjamin Springgate, Peter T. Katzmarzyk

Clinical Research Faculty Publications

Objective: This study tested whether initial weight change (WC), self-weighing, and adherence to the expected WC trajectory predict longer-term WC in an underserved primary-care population with obesity. Methods: Data from the intervention group (n = 452; 88% women; 74% Black; BMI 37.3 kg/m2 [SD: 4.6]) of the Promoting Successful Weight Loss in Primary Care in Louisiana trial were analyzed. Initial (2-, 4-, and 8-week) percentage WC was calculated from baseline clinic weights and daily at-home weights. Weights were considered adherent if they were on the expected WC trajectory (10% at 6 months with lower [7.5%] and upper [12.5%] bounds). Linear …

The Type 1 Diabetes And Exercise Initiative: Predicting Hypoglycemia Risk During Exercise For Participants With Type 1 Diabetes Using Repeated Measures Random Forest, Simon Bergford, Michael C. Riddell, Peter G. Jacobs, Zoey Li, Robin L. Gal, Mark A. Clements, Francis J. Doyle, Corby K. Martin, Susana R. Patton, Jessica R. Castle, Melanie B. Gillingham, Roy W. Beck, Michael R. Rickels, Peter Calhoun

Clinical Research Faculty Publications

Objective: Exercise is known to increase the risk for hypoglycemia in type 1 diabetes (T1D) but predicting when it may occur remains a major challenge. The objective of this study was to develop a hypoglycemia prediction model based on a large real-world study of exercise in T1D. Research Design and Methods: Structured study-specified exercise (aerobic, interval, and resistance training videos) and free-living exercise sessions from the T1D Exercise Initiative study were used to build a model for predicting hypoglycemia, a continuous glucose monitoring value < 70 mg/dL, during exercise. Repeated measures random forest (RMRF) and repeated measures logistic regression (RMLR) models were constructed to predict hypoglycemia using predictors at the start of exercise and baseline characteristics. Models were evaluated with area under the receiver operating characteristic curve (AUC) and balanced accuracy. Results: RMRF and RMLR had similar AUC (0.833 vs. 0.825, respectively) and both models had a balanced accuracy of 77%. The probability of hypoglycemia was higher for exercise sessions with lower pre-exercise glucose levels, negative pre-exercise glucose rates of change, greater percent time < 70 mg/dL in the 24 h before exercise, and greater pre-exercise bolus insulin-on-board (IOB). Free-living aerobic exercises, walking/hiking, and physical labor had the highest probability of hypoglycemia, while structured exercises had the lowest probability of hypoglycemia. Conclusions: RMRF and RMLR accurately predict hypoglycemia during exercise and identify factors that increase the risk of hypoglycemia. Lower glucose, decreasing levels of glucose before exercise, and greater pre-exercise IOB largely predict hypoglycemia risk in adults with T1D.

Sarcopenic Obesity: Emerging Mechanisms And Therapeutic Potential, Christopher L. Axelrod, Wagner S. Dantas, John P. Kirwan

Division of Basic Science Faculty Publications

Sarcopenic obesity, or the loss of muscle mass and function associated with excess adiposity, is a largely untreatable medical condition associated with diminished quality of life and increased risk of mortality. To date, it remains somewhat paradoxical and mechanistically undefined as to why a subset of adults with obesity develop muscular decline, an anabolic stimulus generally associated with retention of lean mass. Here, we review evidence surrounding the definition, etiology, and treatment of sarcopenic obesity with an emphasis on emerging regulatory nodes with therapeutic potential. We review the available clinical evidence largely focused on diet, lifestyle, and behavioral interventions to …

Global Rural Health Disparities In Alzheimer's Disease And Related Dementias: State Of The Science, Lisa Ann Kirk Wiese, Allison Gibson, Marc Aaron Guest, Amy R. Nelson, Raven Weaver, Aditi Gupta, Owen Carmichael, Jordan P. Lewis, Allison Lindauer, Samantha Loi, Rachel Peterson, Kylie Radford, Elizabeth K. Rhodus, Christina G. Wong, Megan Zuelsdorff, Ladan Ghazi Saidi, Esmeralda Valdivieso-Mora, Sanne Franzen, Caitlin N. Pope, Timothy S. Killian, Hom L. Shrestha, Patricia C. Heyn, Ted Kheng Siang Ng, Beth Prusaczyk, Samantha John, Ambar Kulshreshtha, Julia L. Sheffler, Lilah Besser, Valerie Daniel, Magdalena I. Tolea, Justin Miller, Christine Musyimi, Jon Corkey, Veronica Yank

Clinical Research Faculty Publications

INTRODUCTION: Individuals living in rural communities are at heightened risk for Alzheimer's disease and related dementias (ADRD), which parallels other persistent place-based health disparities. Identifying multiple potentially modifiable risk factors specific to rural areas that contribute to ADRD is an essential first step in understanding the complex interplay between various barriers and facilitators. METHODS: An interdisciplinary, international group of ADRD researchers convened to address the overarching question of: “What can be done to begin minimizing the rural health disparities that contribute uniquely to ADRD?” In this state of the science appraisal, we explore what is known about the biological, behavioral, …

Probiotic Characteristics Of Streptococcus Thermophilus And Lactobacillus Bulgaricus As Influenced By New Food Sources, Ashly Castro, Ricardo S. Aleman, Miguel Tabora, Shirin Kazemzadeh, Leyla K. Pournaki, Roberto Cedillos, Jhunior Marcia, Kayanush Aryana

Faculty Publications

The current research aimed to evaluate the potential effects of Solanum mammosum, Dioon mejiae, and Amanita caesarea on Streptococcus thermophilus and Lactobacillus delbrueckii subsp. bulgaricus survival and performance after exposure to different harsh conditions such as bile, acid, gastric juice, and lysozyme to mimic the digestive system from mouth to the intestine. Probiotic protease activity was observed to evaluate the proteolytic system. Probiotics were cultured in a broth mixed with plant material, and after incubation, the results were compared to the control sample. Therefore, plant material’s total phenolic compound, total carotenoid compound, antioxidant activity, sugar profile, and acid profile were …

Effects Of Weevil (Rhynchophorus Palmarum), Teosinte (Dioon Mejiae) And Caesar’S Mushroom (Amanita Caesarea) On The Properties Of Lactobacillus Acidophilus La-K, Ricardo S. Aleman, Dany Avila, Allan Avila, Jhunior Marcia, David Picha, Kayanush Aryana, Ismael Montero-Fernández

Faculty Publications

Weevil (Rhynchophorus palmarum) powder, teosinte (Dioon mejiae) and Caesar’s mushroom (Amanita caesarea) flour have bioactive compounds with significant nutritional applications. This paper aimed to examine the influence of weevil, teosinte, and mushroom powders on the protease activity, acid tolerance, bile tolerance, lysozyme tolerance, and gastric juice resistance ability of Lactobacillus acidophilus LA-K. Acid tolerance was determined by adjusting the pH of MRS broth to 2.0 for L. acidophilus incubated under aerobic conditions at 37 °C. Bile tolerance was determined by incorporating 0.3% of oxgall. Protease activity was determined spectrophotometrically at 340 nm. Resistance to 100 mg/L of lysozyme in an …

Convenience Over Nutrition For Recreation League Youth Sport Team Snack And Mealtime Choices, Morgan Ashley, Tony Weaver, Andrew Ramsey, Lauren Haldeman

Journal of Human Sciences and Extension

Fifty-six percent of school-aged children participate in team sports, yet there is limited evidence on how participation in youth sports impacts the dietary behaviors of participants and their families. Our team surveyed parents and caregivers of children participating in recreation league youth sports (n = 178) to assess the foods and beverages offered as team snacks and factors that influence team snack choices. Juice was the most popular beverage, and crackers were the most popular snack reported by parents. Convenience, followed by cost and child preference, were the most frequently reported factors influencing team snack choices. Survey items also included …

Full Issue, Volume 11, Number 2, Donna J. Peterson, Scott Cummings

Journal of Human Sciences and Extension

No abstract provided.

The Experiences Of Children On Sri Lanka's Tea Plantations: Labor And Sexual Exploitation, Violence, And Inadequate Education, Rathnayake Mudiyanselage Bandaranayake, Glenn M. Miles, Jarrett D. Davis, Madeline Stenersen, Anjum Umrani

Dignity: A Journal of Analysis of Exploitation and Violence

This article explores the difficulties faced by children living in Sri Lanka’s tea plantation areas. Data from 150 children reveal high rates of poverty, violence, and school dropout. Children in tea plantation schools report bullying and stigma from teachers and students. Many children do not envision completing school due to inadequate resources, family income pressures, and the need to work. Children who drop out of school face abusive labor conditions and poor pay. Over 30% of all children report experiencing sexual abuse, often in their own homes. Those working face discrimination, physical abuse, and wage theft. Initiatives are needed to …

Neurocognitive Outcomes Of Children Exposed To And Living With Hiv Aged 3–5 Years In Kilifi, Kenya, Esther Chongwo, Catherine Wedderburn, Moses Kachama, Antipa Sigilai, Paul Mwangi, Janet Thoya, Rachel Odhiambo, Katana Ngombo, Charles Newton, Amina Abubakar

Institute for Human Development, East Africa

Introduction: Globally, 1.7 million children are living with HIV, with the majority of them residing in sub-Saharan Africa. Due to reduced rates of vertical transmission of HIV, there is an increasing population of children born to HIV-infected mothers who remain uninfected. There is a growing concern around the development of these children in the antiretroviral therapy era. This study examined the neurocognitive outcomes of children who are HIV-exposed infected (CHEI), HIV-exposed uninfected (CHEU) and HIV-unexposed uninfected (CHUU) and explored the relationship between child neurocognitive outcomes and child's biomedical and caregivers’ psychosocial factors.

Methods: CHEI, CHUU and CHEU aged 3–5 years …

Influence Of Capacity Building On Nutrition Sensitivity Of The Municipal Agriculture Development Plan In Calabarzon, Philippines, Kim Leonard G. Dela Luna, Maria Theresa M. Talavera, Leila S. Africa, Clarissa B. Juanico, Nancy A. Tandang, Marison Felicidad R. Dy

The Philippine Agricultural Scientist

To improve the nutrition sensitivity of the Municipal Agriculture Development Plan (MADP) of Calabarzon, a one-group pre-test post-test design quasi-experimental study was conducted involving the Local Agriculture Planners (LAP) of 57 municipalities in the region from March to December 2021. Wilcoxon Paired Signed Rank was used to determine significant differences in the nutrition sensitivity of the MADP and level of knowledge, attitude, and self-efficacy of the LAP before and after the intervention. Binary logistic regression analysis was also performed to model the change in the level of the nutrition sensitivity of the MADP. The LAP's level of knowledge, attitude, and …

Effects Of Polishing And Cooking On The Phytochemical Properties And Antioxidant Activities Of Selected Philippine Rice Cultivars [Research Note], Rodel M. Bulatao, Charleo S. Zapanta, Maricar B. Castillo, Reniel P. Tubera, Joel R. Salazar

The Philippine Agricultural Scientist

This paper evaluated the effects of different polishing times and regular cooking on the phytochemical properties and antioxidant activities of black rice Brillante, red rice Minaangan, and white rice NSIC Rc 160. Rice samples were polished for 0, 15, 30, and 45 s, and were cooked using their optimum cooking water ratio. The samples were then characterized for their phytochemical properties [total anthocyanin content (TAC), total phenolic content (TPC), and total flavonoid content (TFC)] and antioxidant activities [DPPH-radical scavenging activity (DPPH-RSA) and ferric reducing antioxidant power (FRAP)]. Pearson’s correlation analysis (PCA) was employed to determine the strength of …

Digestible And Metabolizable Energy In Ground Yellow Corn, Rice Bran, And Copra Meal Fed To 10 To 15 Kg Philippine Native Pigs (Benguet Strain), Mary Arnel D. Garcia

The Philippine Agricultural Scientist

The experiment was conducted to determine the digestible energy (DE), metabolizable energy (ME), and apparent total tract digestibility (ATTD) of gross energy in ground yellow corn, rice bran, and copra meal when fed to Philippine native pigs. Nine barrows with an average initial bodyweight of 10 kg and ages ranging from 60 to 75 d old were housed individually in metabolism crates and randomly allotted to a triplicated incomplete 3 × 2 Latin square design with three diets and two periods. A corn-based diet containing 94.89% yellow corn and two diets containing 66.42% yellow corn and 30% rice bran or …

Allelopathy Of Faba Bean Cover Crop To Durum Wheat Under A Semi-Arid Environment, Oussama Oueslati, Arwa Zammali, Raed Hamdi, Ahlem Dhahri, Chaima Melliti, Moncef Ben Hammouda, Robert Kremer

The Philippine Agricultural Scientist

Problems facing farmers practicing conservation agriculture in the semi-arid zone of Tunisia include appropriate cover crop selection, management of allelopathic effects affecting subsequent crop performance, and influence of seasonal variation on allelopathy expression. Allelopathy expressed by faba bean (Vicia faba L.) toward durum wheat [Triticum turgidum ssp. durum (Desf.) Husn.] was studied using bioassays during three growing seasons. The role of phenols in the expression of such potential was also investigated. Analyses of plant samples at three phenological stages (flowering, fruiting, senescence) revealed that leaves were most inhibitory. Allelopathic potential differed among plant components and phenological stages, with …

Diet-Mediated Heart Disease Risk Via The Gut Microbiome, Emily Bolton

Summer Community of Scholars Posters (RCEU and HCR Combined Programs)

Background: Recent advances in microbiome research suggest the gut microbiome has a role to play in the development of coronary artery disease (CAD). Though the American Heart Association (AHA) has broad dietary recommendations to prevent CAD, the role of the gut microbiome is not considered. The aim of this study is to examine existing literature on the role of probiotics (fermented dairy), prebiotics (high-fiber foods), and processed foods (NOVA groups 3 and 4) on markers of atherosclerosis via the gut microbiome. Methods: A search was conducted for human intervention studies using PubMed, CINAHL, and Embase. Twenty-two articles met eligibility and …

Fall Sustainability Festival, Julia Canuel

Senior Honors Projects

There has been an increased interest in sustainability and “green” products in recent years. In my sophomore year, I started working with the URI Free Farmers’ Market, a group that sustainably grows, harvests and provides students with free produce. My work with the URI FFM inspired me to look into sustainable agriculture and explore what other aspects of a college students’ life could be adapted to be more sustainable. To do this, I created a Fall Sustainability Festival focusing on sustainable initiatives at URI and in the Rhode Island community. The RI Food Policy Council, Rhode Island Office of Energy …

Factors Associated With Per- And Polyfluoroalkyl Substance (Pfas) Concentrations: Implications For Exposure Assessment And Highly Exposed Communities, Jordan Mcadam

Legacy Theses & Dissertations (2009 - 2024)

Background: Per- and polyfluoroalkyl substance exposure has been implicated as a factor contributing to the development of many adverse health outcomes across populations of all ages. Despite this, the factors associated with PFAS concentrations in humans are not well understood. Most studies evaluating factors associated with PFAS concentrations consider a small number of variables. Differences in the factors associated with PFAS levels in populations of high exposure versus low or background exposure (i.e., the general population) have not been considered. Advancing our understanding on this topic is necessary to better understand the serum elimination half-lives and toxicokinetics of PFAS. Additionally, …