Digital Commons Network^™

Building Urban Sustainability With Quality Elites, Havovi Joshi

Asian Management Insights

Do elites contribute to a society more than they extract from it? In many countries where populism has surged in tandem with declining trust in elites in the political and other spheres, the answer.

Rooted In Meaning: Plant Iconography On Nasca Polychrome Ceramics, Amanda G. Lange

Theses

This thesis explores the Nasca use of plant iconography as part of their polychrome ceramics produced at the end of the Early Horizon around 100 BCE to those produced in the beginning and middle of the Early Intermediate Period circa 1to 450 CE. During this time the religious site of Cahuachi was in use as a pilgrimage center as well as the production center of polychrome pottery. The Nasca created their colorful ceramics here to distribute to visiting pilgrims during times of festival or ritual. The culture’s iconography has been studied extensively, most of which focuses on the forms of …

Federal Education Funding Task Force, Tennessee. Comptroller Of The Treasury.

Office of Research and Education Accountability

No abstract provided.

Dean's Research Newsletter, November 2023, Neil W. Schluger

SOM Dean's Research Newsletter

No abstract provided.

Dha Shortage Causes The Early Degeneration Of Photoreceptors And Rpe In Mice With Peroxisomal Β-Oxidation Deficiency, Daniëlle Swinkels, Sai Kocherlakota, Yannick Das, Adriaan D. Dane, Eric J.M. Wever, Frédéric M. Vaz, Nicolas G. Bazan, Paul P. Van Veldhoven, Myriam Baes

School of Medicine Faculty Publications

PURPOSE. Patients deficient in peroxisomal β-oxidation, which is essential for the synthesis of docosahexaenoic acid (DHA, C22:6n-3) and breakdown of very-long-chain polyunsaturated fatty acids (VLC-PUFAs), both important components of photoreceptor outer segments, develop retinopathy present with retinopathy. The representative mouse model lacking the central enzyme of this pathway, multifunctional protein 2 (Mfp2−/−), also show early-onset retinal decay and cell-autonomous retinal pigment epithelium (RPE) degeneration, accompanied by reduced plasma and retinal DHA levels. In this study, we investigated whether DHA supplementation can rescue the retinal degeneration of Mfp2−/− mice. METHODS. Mfp2+/− breeding pairs and their offspring were fed a 0.12% DHA …

Incorporating Over-The-Counter Hearing Aids Into Private Audiology Practice, Ryan K. Anderson

Doctoral Scholarly Projects & Capstones

Over-the-counter (OTC) hearing aids are a new category of hearing aid devices designed to help adults with mild to moderate sensorineural hearing loss. This new category of devices was created with the aim to provide increased access to hearing aids for millions of Americans. Their advent has created significant change for hearing healthcare within the United States as they can be purchased without consulting an audiologist or medical professional.

As a result of these changes, private audiology practice owners must choose how they will react. Moving forward they must decide if they will integrate OTC hearing aids into their practices, …

Recent Developments In Frailty Identification, Management, Risk Factors And Prevention: A Narrative Review Of Leading Journals In Geriatrics And Gerontology, Elsa Dent, Peter Hanlon, Marc Sim, Juulia Jylhävä, Zuyun Liu, Davide L. Vetrano, Erwin Stolz, Mario U. Pérez-Zepeda, Daniel R. Crabtree, Caroline Nicholson, Jenny Job, Rachel C. Ambagtsheer, Paul R. Ward, Sandra M. Shi, Quan Huynh, Emiel O. Hoogendijk

Research outputs 2022 to 2026

Frailty is an age-related clinical condition characterised by an increased susceptibility to stressors and an elevated risk of adverse outcomes such as mortality. In the light of global population ageing, the prevalence of frailty is expected to soar in coming decades. This narrative review provides critical insights into recent developments and emerging practices in frailty research regarding identification, management, risk factors, and prevention. We searched journals in the top two quartiles of geriatrics and gerontology (from Clarivate Journal Citation Reports) for articles published between 01 January 2018 and 20 December 2022. Several recent developments were identified, including new biomarkers and …

Effects Of Jaw Clenching And Mental Stress On Persistent Inward Currents Estimated By Two Different Methods, Ricardo N. O. Mesquita, Janet L. Taylor, Gabriel S. Trajano, Aleš Holobar, Basílio A. M. Gonçalves, Anthony J. Blazevich

Research outputs 2022 to 2026

Spinal motoneuron firing depends greatly on persistent inward currents (PICs), which in turn are facilitated by the neuromodulators serotonin and noradrenaline. The aim of this study was to determine whether jaw clenching (JC) and mental stress (MS), which may increase neuromodulator release, facilitate PICs in human motoneurons. The paired motor unit (MU) technique was used to estimate PIC contribution to motoneuron firing. Surface electromyograms were collected using a 32-channel matrix on gastrocnemius medialis (GM) during voluntary, ramp, plantar flexor contractions. MU discharges were identified, and delta frequency ( F), a measure of recruitment–derecruitment hysteresis, was calculated. Additionally, another technique was …

Building The Soil Carbon Sponge At Murray Wells Farm, Tambellup, Western Australia, Wendy Bradshaw

Natural resources published reports

Peter and Wendy Bradshaw farmed at Murray Wells Farm about 25 km west of Tambellup for around 46 years until they sold and retired in 2022. They produced barley, oats, merino and prime lambs on an annual rainfall of 450 mm over 1,000 arable hectares. The farm was on a moderately undulating landscape with a mix of soils including sandy duplex, well-drained sand over gravel over clay, shallow sandy or loamy gravel over cemented laterite and red to brown loamy soils.Their farming philosophy was to view agriculture as an ecological enterprise that included them as part of the ecosystem, and …

Les Effets Du Changement Climatique Sur La Santé : Expériences Vécues Par Des Jeunes Du Bangladesh, Du Guatemala Et Du Nigeria, Population Council, Women Deliver

Adolescents and Young People

No abstract provided.

Tame The Flame: Inflammation Is A Targetable Physiological Mechanism Underlying Poor Outcomes Of Heat Stress In Finishing Sheep, Pablo C. Grijalva

Dissertations and Doctoral Documents, University of Nebraska-Lincoln, 2023–

This research focused on health management through the identification of suitable interventions in stressed livestock. For this investigation, we conducted two experiments. First, we determined whether administration of dexamethasone or fish oil to heat-stressed livestock to reduce systemic inflammation would mitigate metabolic deficits, enhance nutrient utilization, and improve health. We found that these interventions helped to reduce circulating inflammatory cytokines and improve respiration, muscle glucose metabolism, lipid homeostasis, cardiovascular function, and organ pathology in lambs exposed to 30 days of heat stress. In our second experiment, we performed transcriptomic analyses to identify the underlying mechanisms affecting young offspring following prenatal …

Characterization And Evaluation Of Bioactivity Of Dry Edible Bean And Bean Derived Small Peptides, Bikram Prasad Upadhyaya

Dissertations and Doctoral Documents, University of Nebraska-Lincoln, 2023–

Obesity, diabetes, and their metabolic complications continue to be one of the major global public health concerns with a few effective treatment options. Although regular exercise and a well-balanced diet that includes calories from pulses can be recommended, much remains to be elucidated about the health effects of the various bioactive compounds including peptides and polyphenols present in pulses. Most of the previous studies have focused on individual dietary compounds and only a few investigated the synergistic effect of active compounds in modulating human health. Hence this dissertation aimed first, to provide a comparative evaluation of the overall therapeutic value …

Serum Ferritin Values In Neonates <29 Weeks' Gestation Are Highly Variable And Do Not Correlate With Reticulocyte Hemoglobin Content, Timothy M Bahr, Sylvia Tan, Emily Smith, Sandra S Beauman, Kurt R Schibler, Cathy A Grisby, Jean R Lowe, Edward F Bell, Abbot R Laptook, Seetha Shankaran, David P Carlton, Carrie Rau, Mariana C Baserga, John Flibotte, Kristin Zaterka-Baxter, Michele C Walsh, Abhik Das, Robert D Christensen, Robin K Ohls, Eunice Kennedy Shriver National Institute Of Child Health And Human Development Neonatal Research Network

Pediatrics Research and Scholarship

OBJECTIVES: To compare serum ferritin and RET-He values among extremely low gestational age neonates ELGANs with other markers of iron-deficient erythropoiesis.

STUDY DESIGN: This is a secondary analysis of the NICHD Darbepoetin Trial. Study data from placebo recipients who had a serum ferritin, a RET-He, and a mean corpuscular volume (MCV) measurement within a 24-hour period were analyzed for correlation.

RESULTS: Mixed linear regression models showed no association between ferritin and RET-He at both early (β = 0.0016, p = 0.40) and late (β = -0.0001, p = 0.96) time points. Positive associations were observed between RET-He and MCV at …

Improving Yield And Profit In Smallholder Oil Palm Fields Through Better Agronomy, Hendra Sugianto

Dissertations and Doctoral Documents, University of Nebraska-Lincoln, 2023–

Oil palm accounts for 40% of global vegetable oil production and Indonesia contributed 59% of the total production, with total planted area nearly 15 M ha in 2020. About 40% of the planted area is managed and owned by smallholders, and two thirds of them are independent, they are not bounded to a large plantation. Current efforts to increase yield of independent smallholder (ISH) fields focus on replanting programs promoting use of certified planting material, with little attention to improve management practices, in particular, plant nutrition. Here we investigated the degree to which poor nutrition can explain large yield gaps …

A Critical Exploration Of Unequal School Funding: Teacher Job Satisfaction Across Underfunded And Well-Funded Schools, David Tomasic

Theses & Dissertations

Unequal school funding is a phenomenon that promotes an educational structure where certain public schools receive higher financial support and resources while other schools receive lower levels. An important but overlooked dimension of the phenomenon is its potential effect on teacher job satisfaction in underfunded and well-funded schools. This dimension forms the basis of this study and exploration of the phenomenon of unequal school funding. Using Susan Moore Johnson's framework, this qualitative phenomenological study aimed to understand how unequal school funding affected nine high school teachers across both under and well-funded high schools on Long Island. The study sought to …

Economic Equity And People With Disabilities: Development And Characterization Of A Novel Index, Bhavneet Walia, Katherine Mcdonald, Joy Hammel, Lex Frieden, Michael Morris, Barry Whaley, Vinh Nguyen

Faculty, Staff and Student Publications

Here we develop two new social indices: The ADA PARC Absolute Economic Opportunity Index and the ADA PARC Relative Economic Opportunity Index. These indices allow us novel examinations of economic equity between people with and without disabilities within a U.S. State and between people with disabilities in different states using aggregations of multiple component economic indicators. These represent the first efforts to offer U.S. indices of this focus, an important development given the distinct economic needs of people with disabilities and the value in accounting for distinct national policies. The indices rely on U.S. Census and other data on economic …

Exercise Training Reduces The Inflammatory Response And Promotes Intestinal Mucosa-Associated Immunity In Lynch Syndrome, Nan Deng, Laura Reyes-Uribe, Johannes F Fahrmann, Whittney S Thoman, Mark F Munsell, Jennifer B Dennison, Eunice Murage, Ranran Wu, Ernest T Hawk, Selvi Thirumurthi, Patrick M Lynch, Christina M Dieli-Conwright, Alexander J Lazar, Sonali Jindal, Khoi Chu, Manoj Chelvanambi, Karen Basen-Engquist, Yisheng Li, Jennifer A Wargo, Florencia Mcallister, James P Allison, Padmanee Sharma, Krishna M Sinha, Samir Hanash, Susan C Gilchrist, Eduardo Vilar

Faculty, Staff and Student Publications

PURPOSE: Lynch syndrome (LS) is a hereditary condition with a high lifetime risk of colorectal and endometrial cancers. Exercise is a non-pharmacologic intervention to reduce cancer risk, though its impact on patients with LS has not been prospectively studied. Here, we evaluated the impact of a 12-month aerobic exercise cycling intervention in the biology of the immune system in LS carriers.

PATIENTS AND METHODS: To address this, we enrolled 21 patients with LS onto a non-randomized, sequential intervention assignation, clinical trial to assess the effect of a 12-month exercise program that included cycling classes 3 times weekly for 45 minutes …

Early Skeletal Muscle Loss In Adolescent And Young Adult Cancer Patients Treated With Anthracycline Chemotherapy, Savannah V Wooten, Fei Wang, Michael E Roth, Guanshu Liu, J Andrew Livingston, Behrang Amini, Susan C Gilchrist, Michelle Hildebrandt, Eugenie S Kleinerman

Faculty, Staff and Student Publications

BACKGROUND: Early skeletal muscle loss has been observed in adolescent and young adult (AYA) sarcoma patients undergoing treatment. Identification of individuals within the AYA populace that are at greatest risk of anthracycline-induced skeletal muscle loss is unknown. Moreover, investigations which seek out underlying causes of skeletal muscle degradation during chemotherapy are critical for understanding, preventing, and reducing chronic health conditions associated with poor skeletal muscle status.

METHODS: Computed tomography (CT) scans were used to investigate changes in skeletal muscle of 153 AYA sarcoma and Hodgkin lymphoma patients at thoracic vertebra 4 after anthracycline treatment. Images were examined at three time …

Vol 3 November '23 Cover, Publishing And Table Of Contents, Donna L. Williams

Journal of the Louisiana Public Health Association

No abstract provided.

Vol 3 November '23 Full Issue, Donna L. Williams

Journal of the Louisiana Public Health Association

No abstract provided.

Delivering Healthcare To The Underserved, Edward Booty

Asian Management Insights

Non-profits, governments, and businesses need to come together and use a data-driven approach to improve local basic healthcare access.

Leading By Example And Giving Back To Society, N.R. Narayana Murthy, Havovi Joshi

Asian Management Insights

N.R. Narayana Murthy, the founder and former Chairman of Infosys, a global provider of next-generation digital services and consulting, speaks with Havovi Joshi about the Indian growth story.

Acute Hepatic Porphyrias: Recommendations For Diagnosis And Management With Real-World Examples, Akshata Moghe, Amy Dickey, Angelika Erwin, Rebecca K. Leaf, Alan O'Brien, John G. Quigley, Manish Thapar, Karl E. Anderson

Division of Gastroenterology and Hepatology Faculty Papers

Acute hepatic porphyria (AHP) is a group of four rare inherited diseases, each resulting from a deficiency in a distinct enzyme in the heme biosynthetic pathway. Characterized by acute neurovisceral symptoms that may mimic other medical and psychiatric conditions, lack of recognition of the disease often leads to a delay in diagnosis and initiation of effective treatment. Biochemical testing for pathway intermediates that accumulate when the disease is active forms the basis for screening and establishing a diagnosis. Subsequent genetic analysis identifies the pathogenic variant, supporting screening of family members and genetic counseling. Management of AHP involves avoidance of known …

Human Schwann Cells In Vitro I. Nerve Tissue Processing, Pre-Degeneration, Isolation, And Culturing Of Primary Cells, Gabriela I. Aparicio, Paula V. Monje

Markey Cancer Center Faculty Publications

This paper presents versatile protocols to prepare primary human Schwann cell (hSC) cultures from mature peripheral nervous system tissues, including fascicles from long spinal nerves, nerve roots, and ganglia. This protocol starts with a description of nerve tissue procurement, handling, and dissection to obtain tissue sections suitable for hSC isolation and culturing. A description follows on how to disintegrate the nerve tissue by delayed enzymatic dissociation, plate the initial cell suspensions on a two-dimensional substrate, and culture the primary hSCs. Each section contains detailed procedures, technical notes, and background information to aid investigators in understanding and managing all steps. Some …

Combatting A Crisis Of Global Food Protectionism Sparked By The War In Ukraine, Daniel C.K. Chow, Ian M. Sheldon

Vanderbilt Journal of Transnational Law

The world is currently gripped in a food crisis of historic proportions that is threatening tens of millions of people in the poorest countries of the world with famine and starvation. Sparked by the war in Ukraine, this crisis is being made worse by nations imposing export restrictions on food in a misguided attempt to curb soaring domestic food prices. Export restrictions are "beggar-thy-neighbor" policies that prevent increases in domestic food prices but at the expense of raising world prices, exacerbating the crisis. Although nations have turned to the World Trade Organization (WTO) for help in removing these export restrictions, …

A New Green Wave: Lessons From Argentina's Marea Verde For Legalizing Abortion Over Religious Opposition In The United States, Morgan Peck

Vanderbilt Journal of Transnational Law

This Note examines the role Christianity, particularly Roman Catholicism, played in influencing abortion laws in the United States and Argentina and offers a solution for new federal protections of abortion rights in the United States. Part II discusses the evolution of abortion rights in both countries, from their foundations to their recent reversals. Part III scrutinizes the ways in which religious ideology factored into the different logical frameworks utilized by the different parties involved in the fight for abortion access, the relevant tactics employed, and the subsequent outcomes. Considering the impact in Argentina of US jurisprudence regarding abortion rights, the …

Construction Of Esg Evaluation Index System Of State-Owned Listed Companies: Analysis Based On The Perspective Of Comprehensive Corporate Value, Yiping Sun

Dissertations and Theses Collection (Open Access)

In this paper, I explore the applicability of environmental, social, and governance (ESG) evaluation systems to Chinese state-owned enterprises (SOEs). I assess these ESG evaluation systems in terms of the overall value of Chinese SOEs and point out that these enterprises do not have their own evaluation system. Establishing an ESG system for Chinese SOEs can encourage them to disclose quantifiable indicators, thus objectively demonstrating their comprehensive ESG performance and helping to enhance their overall value. I examine the current ESG evaluation systems in detail and find that there are many problems in applying the main international evaluation systems to …

The Health Effects Of Climate Change: Experiences Of Young People In Bangladesh, Guatemala, And Nigeria, Population Council, Women Deliver

Adolescents and Young People

Climate change is affecting the health and well-being of adolescents and young people (AYP) worldwide. This happens through direct exposure pathways but mainly indirectly, by influencing economic and food insecurity, access to health services, and harmful gender norms and social inequalities. According to a recent meta-analysis of 130 studies, climate change disproportionately harms the health of women and girls, especially younger generations. There are intergenerational inequities in exposure to climate extremes. A child born in 2020 will face an up to sevenfold increase in extreme climate events compared to one born in 1960. These events will have cascading harms and …

Corrigendum To 'Pressure-Mediated Reflection Spectroscopy Criterion Validity As A Biomarker Of Fruit And Vegetable Intake: A 2-Site Cross-Sectional Study Of 4 Racial Or Ethnic Groups' [J Nutr 2022;152:107-116], Stephanie B Jilcott Pitts, Nancy E Moran, Qiang Wu, Lisa Harnack, Neal E Craft, Neil Hanchard, Ronny Bell, Stacey G Moe, Nevin Johnson, Justice Obasohan, Pamela L Carr-Manthe, Melissa N Laska

Children’s Nutrition Research Center Staff Publications

No abstract provided.

Examining Potential Modifiers Of Human Skin And Plasma Carotenoid Responses In A Randomized Trial Of A Carotenoid-Containing Juice Intervention, Stephanie B Jilcott Pitts, Qiang Wu, Nancy E Moran, Melissa N Laska, Lisa Harnack

Children’s Nutrition Research Center Staff Publications

Background: Skin carotenoid measurements are emerging as a valid and reliable indicator of fruit and vegetable intake and carotenoid intake. However, little is known about the extent to which skin carotenoid responsivity to dietary changes differs based on demographic and physiologic characteristics.

Objectives: This study examined potential effect modifiers of skin carotenoid and plasma carotenoid responses to a carotenoid-rich juice intervention.

Methods: We leveraged data from 2 arms of a 3-site randomized controlled trial of a carotenoid-containing juice intervention (moderate dose = 6 ounces juice, 4 mg total carotenoids/d, high dose = 12 ounces juice, 8 mg total carotenoids/d) (n …