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Increasing The Acceptance Of Cultivated Meat, Mark Chong Nov 2023

Increasing The Acceptance Of Cultivated Meat, Mark Chong

Asian Management Insights

Factors to consider when designing communication strategies for diverse nations.


Grazing Stubbles And Dry Pasture, Department Of Primary Industries And Regional Development, Western Australia Nov 2023

Grazing Stubbles And Dry Pasture, Department Of Primary Industries And Regional Development, Western Australia

Animal production and livestock factsheets

Dry pastures in Western Australia provide good early feed after senescence but rapidly become unable to maintain stock. Stubbles are the major feed source for sheep during the summer-autumn period.

While there is often up to three tonnes of dry plant material per hectare available, sheep grazing stubbles eat only about 6% of it. With increased harvesting efficiency and better weed control, stubble paddocks now generally contain less grain and fewer weeds than in the past.


Biological And Environmental Factors May Affect Children’S Executive Function Through Motor And Sensorimotor Development: Preterm Birth And Cerebral Palsy, Iryna Babik, Andrea B. Cunha, Sudha Srinivasan Nov 2023

Biological And Environmental Factors May Affect Children’S Executive Function Through Motor And Sensorimotor Development: Preterm Birth And Cerebral Palsy, Iryna Babik, Andrea B. Cunha, Sudha Srinivasan

Psychological Sciences Faculty Publications and Presentations

Disruptive biological and environmental factors may undermine the development of children’s motor and sensorimotor skills. Since the development of cognitive skills, including executive function, is grounded in early motor and sensorimotor experiences, early delays or impairments in motor and sensorimotor processing often trigger dynamic developmental cascades that lead to suboptimal executive function outcomes. The purpose of this perspective paper is to link early differences in motor/sensorimotor processing to the development of executive function in children born preterm or with cerebral palsy. Uncovering such links in clinical populations would improve our understanding of developmental pathways and key motor and sensorimotor skills …


Uab Nurse-Family Partnership Awarded $8.8 Million To Increase Maternity Care Access In Alabama, Staff Nov 2023

Uab Nurse-Family Partnership Awarded $8.8 Million To Increase Maternity Care Access In Alabama, Staff

Browse All News

No abstract provided.


The Evaluation Of Calsporin And Imw50 On Production Performance, Microbial Population, And Immune Function Of The Laying Hen, Kayla N. Kleist Nov 2023

The Evaluation Of Calsporin And Imw50 On Production Performance, Microbial Population, And Immune Function Of The Laying Hen, Kayla N. Kleist

Master's Theses

The use of antibiotics as growth promotors in the food animal industry has led to the generation of antibiotic resistant microorganisms, which are a major health risk to humans. Therefore, bans and limitations, including the FDA’s veterinary feed directive, have been placed on the use of antibiotics as growth promotors, and there has been a push to find an adequate alternative. In the laying hen, probiotics and/or prebiotics have shown promise as they help promote the colonization of beneficial bacteria in the GI tract of the host, increase feed efficiency, increase egg production, and provide protection against pathogenic bacteria.

In …


Emulating Evolutionary Principles For Agriculture: Designing A Biomimetic Vertical Garden By Mimicking Tracheophyte Evolution, Earl M. Riddell Nov 2023

Emulating Evolutionary Principles For Agriculture: Designing A Biomimetic Vertical Garden By Mimicking Tracheophyte Evolution, Earl M. Riddell

Honors Theses

Biodiversity, particularly in the world’s equatorial regions, is under threat from human industry. Among the most daunting problems facing these biomes is that of the food industry’s continual expansion into what was once rainforest. Expansive monoculture (large cultivated swaths of a single crop species) are the primary threat to tropical biodiversity. This method of agriculture is harmful because it requires the clearing of land that once supported thousands of species in order to replace it with rows of a single crop. If more plants could be grown in a smaller horizontal square footage, farms need not rely so heavily on …


Sarcopenia Is Associated With Osteopenia And Impaired Quality Of Life In Children With Genetic Intrahepatic Cholestatic Liver Disease, Julia Boster, Nathan P. Goodrich, Cathie Spino, Kathleen M. Loomes, Estella M. Alonso, Binita M. Kamath, Ronald J. Sokol, Saul J. Karpen, Alexander Miethke, Benjamin L. Shneider, Jean P. Molleston, Rohit Kohli, Simon P. Horslen, Philip Rosenthal, Pamela L. Valentino, Jeffrey Teckman, Thomas N. Hangartner, Sundaram Shikha Nov 2023

Sarcopenia Is Associated With Osteopenia And Impaired Quality Of Life In Children With Genetic Intrahepatic Cholestatic Liver Disease, Julia Boster, Nathan P. Goodrich, Cathie Spino, Kathleen M. Loomes, Estella M. Alonso, Binita M. Kamath, Ronald J. Sokol, Saul J. Karpen, Alexander Miethke, Benjamin L. Shneider, Jean P. Molleston, Rohit Kohli, Simon P. Horslen, Philip Rosenthal, Pamela L. Valentino, Jeffrey Teckman, Thomas N. Hangartner, Sundaram Shikha

Biomedical, Industrial & Human Factors Engineering Faculty Publications


Background:
Sarcopenia occurs in pediatric chronic liver disease, although the prevalence and contributing factors in genetic intrahepatic cholestasis are not well-described. The objective of this study was to measure muscle mass in school-aged children with genetic intrahepatic cholestasis and assess relationships between sarcopenia, clinical variables, and outcomes.

Methods:
Estimated skeletal muscle mass (eSMM) was calculated on dual-energy x-ray absorptiometry obtained in a Childhood Liver Disease Research Network study of children with bile acid synthesis disorders(BASD) alpha-1 antitrypsin deficiency (a1ATd), chronic intrahepatic cholestasis (CIC), and Alagille syndrome (ALGS). Relationships between eSMM, liver disease, and transplant-free survival were assessed.

Results:
eSMM was …


Effects Of Ingested Essential Oils And Propolis Extracts On Honey Bee (Hymenoptera: Apidae) Health And Gut Microbiota, Allyson Martin Ewert, Michael Simone-Finstrom, Quentin Read, Claudia Husseneder, Vincent Ricigliano Nov 2023

Effects Of Ingested Essential Oils And Propolis Extracts On Honey Bee (Hymenoptera: Apidae) Health And Gut Microbiota, Allyson Martin Ewert, Michael Simone-Finstrom, Quentin Read, Claudia Husseneder, Vincent Ricigliano

Faculty Publications

Managed honey bee (Hymenoptera: Apidae: Apis mellifera Linnaeus) hives require frequent human inputs to maintain colony health and productivity. A variety of plant natural products (PNPs) are delivered via feeding to control diseases and reduce the use of synthetic chemical treatments. However, despite their prevalent use in beekeeping, there is limited information regarding the impact of ingested PNPs on bee health. Here, we tested the effects of different essential oils and propolis extracts on honey bee life span, nutrient assimilation, xenobiotic detoxification, and gut microbiota abundance. Brazilian propolis extract lengthened worker life span, while the other PNPs (Louisiana propolis extract, …


Weight And Protozoa Number But Not Bacteria Diversity Are Associated With Successful Pair Formation Of Dealates In The Formosan Subterranean Termite, Coptotermes Formosanus, Junyan Chen, Garima Setia, Li Hsiang Lin, Qian Sun, Claudia Husseneder Nov 2023

Weight And Protozoa Number But Not Bacteria Diversity Are Associated With Successful Pair Formation Of Dealates In The Formosan Subterranean Termite, Coptotermes Formosanus, Junyan Chen, Garima Setia, Li Hsiang Lin, Qian Sun, Claudia Husseneder

Faculty Publications

New colonies of Formosan subterranean termites are founded by monogamous pairs. During swarming season, alates (winged reproductives) leave their parental colony. After swarming, they drop to the ground, shed their wings, and male and female dealates find suitable nesting sites where they mate and become kings and queens of new colonies. The first generation of offspring is entirely dependent on the nutritional resources of the founder pair consisting of the fat and protein reserves of the dealates and their microbiota, which include the cellulose-digesting protozoa and diverse bacteria. Since termite kings and queens can live for decades, mate for life …


Validity Of An Artificial Intelligence-Based Application To Identify Foods And Estimate Energy Intake Among Adults: A Pilot Study, Chloe P. Lozano, Emma N. Canty, Sanjoy Saha, Stephanie T. Broyles, Robbie A. Beyl, John W. Apolzan, Corby K. Martin Nov 2023

Validity Of An Artificial Intelligence-Based Application To Identify Foods And Estimate Energy Intake Among Adults: A Pilot Study, Chloe P. Lozano, Emma N. Canty, Sanjoy Saha, Stephanie T. Broyles, Robbie A. Beyl, John W. Apolzan, Corby K. Martin

Clinical Research Faculty Publications

Background: The commercial application Openfit allows for automatic identification and quantification of food intake through short video capture without a physical reference marker. There are no known peer-reviewed publications on the validity of this Nutrition Artificial Intelligence (AI). Objectives: To test the validity of Openfit to identify food automatically and semiautomatically (with user correction), test the validity of Openfit at quantifying energy intake (kcal) automatically and semiautomatically, and assess satisfaction and usability of Openfit. Methods: During a laboratory-based visit, adults (7 male and 17 female), used Openfit to automatically and semiautomatically record provided meals, which were covertly weighed. Foods logged …


Low Movement, Deep-Learned Sitting Patterns, And Sedentary Behavior In The International Study Of Childhood Obesity, Lifestyle And The Environment (Iscole), Paul R. Hibbing, Jordan A. Carlson, Chelsea Steel, Mikael Anne Greenwood-Hickman, Supun Nakandala, Marta M. Jankowska, John Bellettiere, Jingjing Zou, Andrea Z. Lacroix, Arun Kumar, Peter T. Katzmarzyk, Loki Natarajan Nov 2023

Low Movement, Deep-Learned Sitting Patterns, And Sedentary Behavior In The International Study Of Childhood Obesity, Lifestyle And The Environment (Iscole), Paul R. Hibbing, Jordan A. Carlson, Chelsea Steel, Mikael Anne Greenwood-Hickman, Supun Nakandala, Marta M. Jankowska, John Bellettiere, Jingjing Zou, Andrea Z. Lacroix, Arun Kumar, Peter T. Katzmarzyk, Loki Natarajan

Population and Public Health Science Faculty Publications

Background/Objectives: Sedentary behavior (SB) has both movement and postural components, but most SB research has only assessed low movement, especially in children. The purpose of this study was to compare estimates and health associations of SB when derived from a standard accelerometer cut-point, a novel sitting detection technique (CNN Hip Accelerometer Posture for Children; CHAP-Child), and both combined. Methods: Data were from the International Study of Childhood Obesity, Lifestyle, and the Environment (ISCOLE). Participants were 6103 children (mean ± SD age 10.4 ± 0.56 years) from 12 countries who wore an ActiGraph GT3X+ accelerometer on the right hip for approximately …


Bariatric Surgery Alters Mitochondrial Function In Gut Mucosa, Robert C. Ross, Elizabeth C. Heintz, Elizabeth R.M. Zunica, R. Leigh Townsend, Amanda E. Spence, Philip R. Schauer, John P. Kirwan, Christopher L. Axelrod, Vance L. Albaugh Nov 2023

Bariatric Surgery Alters Mitochondrial Function In Gut Mucosa, Robert C. Ross, Elizabeth C. Heintz, Elizabeth R.M. Zunica, R. Leigh Townsend, Amanda E. Spence, Philip R. Schauer, John P. Kirwan, Christopher L. Axelrod, Vance L. Albaugh

Division of Basic Science Faculty Publications

Background: The obesity pandemic has worsened global disease burden, including type 2 diabetes, cardiovascular disease, and cancer. Metabolic/bariatric surgery (MBS) is the most effective and durable obesity treatment, but the mechanisms underlying its long-term weight loss efficacy remain unclear. MBS drives substrate oxidation that has been linked to improvements in metabolic function and improved glycemic control that are potentially mediated by mitochondria—a primary site of energy production. As such, augmentation of intestinal mitochondrial function may drive processes underlying the systemic metabolic benefits of MBS. Herein, we applied a highly sensitive technique to evaluate intestinal mitochondrial function ex vivo in a …


Access, Interest, And Barriers To Incorporation Of Birth Doula Care In The United States, Amanda W. Mitchell, Joshua R. Sparks, Robbie A. Beyl, Abby D. Altazan, S. Ariel Barlow, Leanne M. Redman Nov 2023

Access, Interest, And Barriers To Incorporation Of Birth Doula Care In The United States, Amanda W. Mitchell, Joshua R. Sparks, Robbie A. Beyl, Abby D. Altazan, S. Ariel Barlow, Leanne M. Redman

Clinical Research Faculty Publications

Doula care improves maternal care, yet barriers exist to incorporating doula care. The purpose of this study was to evaluate interest and barriers to doula care. Overall, 508 women, 26–35 years of age (54.5%), White/Caucasian (89.8%), and married (88.6%), completed this study. Most reported ≥1 previous birth (97.6%). Respondents would “feel comfortable” (73.2%) and “more confident” (54.9%) with doula care at birth, and 57.9% reported their provider would be supportive of doula care. Only 39.0% expressed benefits to doula care during pregnancy compared to 72.6% at birth and 68.1% during postpartum. Most would hire a doula if health insurance covered …


Erratum To ‘P23-075-23 Development & Validating Of A Food Literacy Behavior Questionnaire For Adults With Type 2 Diabetes Mellitus’ [Current Developments In Nutrition 7s1 (2023) 100184] (Current Developments In Nutrition (2023) 7(S1), (S2475299123249094), (10.1016/J.Cdnut.2023.100184)), Sarah Ludwig, Melissa Cater, Georgianna Tuuri Nov 2023

Erratum To ‘P23-075-23 Development & Validating Of A Food Literacy Behavior Questionnaire For Adults With Type 2 Diabetes Mellitus’ [Current Developments In Nutrition 7s1 (2023) 100184] (Current Developments In Nutrition (2023) 7(S1), (S2475299123249094), (10.1016/J.Cdnut.2023.100184)), Sarah Ludwig, Melissa Cater, Georgianna Tuuri

Faculty Publications

The American Society of Nutrition regrets that the author order of this abstract is incorrect. The author order is currently listed as: Georgianna Tuuri, Melissa Cater, Sarah Ludwig The author order should be: Sarah Ludwig, Melissa Cater, Georgianna Tuuri The Society would like to apologise for any inconvenience caused.


Responses Of Phytoplankton Communities To The Effect Of Both River Plume And Coastal Upwelling, Zhuyin Tong, Lingqi Ma, Shujie Cai, Lei Wang, Wupeng Xiao, Bangqin Huang, Edward A. Laws Nov 2023

Responses Of Phytoplankton Communities To The Effect Of Both River Plume And Coastal Upwelling, Zhuyin Tong, Lingqi Ma, Shujie Cai, Lei Wang, Wupeng Xiao, Bangqin Huang, Edward A. Laws

Faculty Publications

River plumes and coastal upwelling systems are both nutrient-abundant habitats compared to the open ocean, and the mechanisms that structure the phytoplankton community when these occur together are unclear. In this study we investigated the dynamics and drivers of phytoplankton biomass and community composition in the Pearl River plume-coastal upwelling system on the northern South China Sea shelf during summer. We found that phytoplankton biomass was lower in the plume than in upwelled water. Diatoms were the only dominant group in the upwelled water. In contrast, diatoms and Synechococcus were co-dominant in the plume, and the negative correlation between the …


Influences Of Yogurt With Functional Ingredients From Various Sources That Help Treat Leaky Gut On Intestinal Barrier Dysfunction In Caco-2 Cells, Ricardo S. Aleman, Ryan Page, Roberto Cedillos, Ismael Montero-Fernández, Jhunior Abraham Marcia Fuentes, Douglas W. Olson, Kayanush Aryana Nov 2023

Influences Of Yogurt With Functional Ingredients From Various Sources That Help Treat Leaky Gut On Intestinal Barrier Dysfunction In Caco-2 Cells, Ricardo S. Aleman, Ryan Page, Roberto Cedillos, Ismael Montero-Fernández, Jhunior Abraham Marcia Fuentes, Douglas W. Olson, Kayanush Aryana

Faculty Publications

The impact of yogurts made with starter culture bacteria (L. bulgaricus and S. thermophilus) and supplemented with ingredients (maitake mushrooms, quercetin, L-glutamine, slippery elm bark, licorice root, N-acetyl-D-glucosamine, zinc orotate, and marshmallow root) that can help treat leaky gut were investigated using the Caco-2 cell monolayer as a measure of intestinal barrier dysfunction. Milk from the same source was equally dispersed into nine pails, and the eight ingredients were randomly allocated to the eight pails. The control had no ingredients. The Caco-2 cells were treated with isoflavone genistein (negative control) and growth media (positive control). Inflammation was stimulated using an …


World Allergy Organization (Wao) Diagnosis And Rationale For Action Against Cow's Milk Allergy (Dracma) Guidelines Update – X – Breastfeeding A Baby With Cow's Milk Allergy, Vicki Mcwilliam, Merryn Netting, Evelyn Volders, Debra Palmer, Ignacio Ansotegui, Stefania Arasi, Amal H. Assa'ad, Sami L. Bahna, Antonio Bognanni, Rose Kamenwa Nov 2023

World Allergy Organization (Wao) Diagnosis And Rationale For Action Against Cow's Milk Allergy (Dracma) Guidelines Update – X – Breastfeeding A Baby With Cow's Milk Allergy, Vicki Mcwilliam, Merryn Netting, Evelyn Volders, Debra Palmer, Ignacio Ansotegui, Stefania Arasi, Amal H. Assa'ad, Sami L. Bahna, Antonio Bognanni, Rose Kamenwa

Paediatrics and Child Health, East Africa

Cow’s milk allergy is rare in exclusively breastfed infants. To support the continuation of breastfeeding an infant after diagnosis with a cow’s milk allergy, it is critical to examine the evidence for and against any form of cow’s milk elimination diet for lactating mothers. In this narrative review, we highlight the lack of high-quality evidence, hence subsequent controversy, regarding whether the minuscule quantities of cow’s milk proteins detectable in human milk cause infant cow’s milk allergy symptoms. Current clinical practice recommendations advise a 2–4 week trial of maternal cow’s milk dietary elimination for: a) IgE-mediated cow’s milk allergy only if …


Prevalence And Factors Associated With Stillbirths Among Women Giving Birth In Four Hospitals Of Eswatini- A Multi-Centre Study, Phetsile Nolungelo Thwala Nov 2023

Prevalence And Factors Associated With Stillbirths Among Women Giving Birth In Four Hospitals Of Eswatini- A Multi-Centre Study, Phetsile Nolungelo Thwala

MSc in Advanced Practice Midwifery

Background: Stillbirth, a component of perinatal mortality, remains a global burden, with approximately 2 million occurring annually worldwide and mostly in low- and middle-income countries (LMICs). There is a dearth of studies on stillbirth in some Low-middle income countries, such as Eswatini. The purpose of this study was to assess the prevalence and associated factors for stillbirths among women giving birth in four selected hospitals in Eswatini.

Methods: A quantitative unmatched case-control study was conducted using records of stillbirths (cases) and live births (controls) from July 1 to December 31, 2021. Consecutive sampling and systematic random sampling were …


Nurses' Experiences And Perspectives Of The Telehealth Working Environment And Educational Needs, Stacee M. Lerret, Susan A. Nuccio, Alyssa Compton, Maria Keegan, Kathryn Rapala Nov 2023

Nurses' Experiences And Perspectives Of The Telehealth Working Environment And Educational Needs, Stacee M. Lerret, Susan A. Nuccio, Alyssa Compton, Maria Keegan, Kathryn Rapala

College of Nursing Faculty Research and Publications

Background:

The continuing evolution of health care and the nursing profession includes the exponential growth of telehealth platforms. The goal of this study was to describe nurses' experiences with and perspectives on their practice with and future need for telehealth.

Method:

A cross-sectional descriptive mixed methods study was conducted with nursing graduates from a single university. Completed survey questions focused on demographics, current work status, plans for employment participation, and telehealth experience. Descriptive analysis was conducted with statistical software, with directed content analysis for narrative responses.

Results:

A total of 305 of 5,080 participants completed the survey (6% response rate). …


Effect Of Sampling Method On Detection Of The Equine Uterine Microbiome During Estrus, B. A. Heil, M. Van Heule, S. K. Thompson, T. A. Kearns, E. L. Oberhaus, G. King, P. Daels, P. Dini, J. L. Sones Nov 2023

Effect Of Sampling Method On Detection Of The Equine Uterine Microbiome During Estrus, B. A. Heil, M. Van Heule, S. K. Thompson, T. A. Kearns, E. L. Oberhaus, G. King, P. Daels, P. Dini, J. L. Sones

Faculty Publications

Bacterial endometritis is among the most common causes of subfertility in mares. It has a major economic impact on the equine breeding industry. The sensitivity of detecting uterine microbes using culture-based methods, irrespective of the sample collection method, double-guarded endometrial swab, endometrial biopsy, or uterine low-volume lavage (LVL), is low. Therefore, equine bacterial endometritis often goes undiagnosed. Sixteen individual mares were enrolled, and an endometrial sample was obtained using each method from all mares. After trimming, quality control and decontamination, 3824 amplicon sequence variants were detected in the dataset. We found using 16S rRNA sequencing that the equine uterus harbors …


Supporting Adolescents' Participation In Muscle-Strengthening Physical Activity: Protocol For The 'Resistance Training For Teens' (Rt4t) Hybrid Type Iii Implementation-Effectiveness Trial, Hayden T. Kelly, Jordan J. Smith, Angeliek Verdonschot, Sarah G. Kennedy, Joseph J. Scott, Heather Mckay, Nicole Nathan, Rachel Sutherland, Philip J. Morgan, Jo Salmon, Dawn Penney, James Boyer, Rhodri S. Lloyd, Christopher Oldmeadow, Penny Reeves, Kirrilly Pursey, Myna Hua, Sarah Longmore, Jennifer Norman, Alexander Voukelatos, Avigdor Zask, David R. Lubans Nov 2023

Supporting Adolescents' Participation In Muscle-Strengthening Physical Activity: Protocol For The 'Resistance Training For Teens' (Rt4t) Hybrid Type Iii Implementation-Effectiveness Trial, Hayden T. Kelly, Jordan J. Smith, Angeliek Verdonschot, Sarah G. Kennedy, Joseph J. Scott, Heather Mckay, Nicole Nathan, Rachel Sutherland, Philip J. Morgan, Jo Salmon, Dawn Penney, James Boyer, Rhodri S. Lloyd, Christopher Oldmeadow, Penny Reeves, Kirrilly Pursey, Myna Hua, Sarah Longmore, Jennifer Norman, Alexander Voukelatos, Avigdor Zask, David R. Lubans

Research outputs 2022 to 2026

INTRODUCTION: In Australia, only 22% of male and 8% of female adolescents meet the muscle-strengthening physical activity guidelines, and few school-based interventions support participation in resistance training (RT). After promising findings from our effectiveness trial, we conducted a state-wide dissemination of the 'Resistance Training for Teens' (RT4T) intervention from 2015 to 2020. Despite high estimated reach, we found considerable variability in programme delivery and teachers reported numerous barriers to implementation. Supporting schools when they first adopt evidence-based programmes may strengthen programme fidelity, sustainability, and by extension, programme impact. However, the most effective implementation support model for RT4T is unclear. OBJECTIVE: …


P2y2 Purinergic Receptor Gene Deletion Protects Mice From Bacterial Endotoxin And Sepsis-Associated Liver Injury And Mortality, Athis R Arunachalam, Sanju S Samuel, Arunmani Mani, Janielle P Maynard, Kelsey M Stayer, Eric Dybbro, Subapradha Narayanan, Aalekhya Biswas, Saliha Pathan, Krishnakant Soni, Abu Hena Mostafa Kamal, Chandra Shekar R Ambati, Nagireddy Putluri, Moreshwar S Desai, Sundararajah Thevananther Nov 2023

P2y2 Purinergic Receptor Gene Deletion Protects Mice From Bacterial Endotoxin And Sepsis-Associated Liver Injury And Mortality, Athis R Arunachalam, Sanju S Samuel, Arunmani Mani, Janielle P Maynard, Kelsey M Stayer, Eric Dybbro, Subapradha Narayanan, Aalekhya Biswas, Saliha Pathan, Krishnakant Soni, Abu Hena Mostafa Kamal, Chandra Shekar R Ambati, Nagireddy Putluri, Moreshwar S Desai, Sundararajah Thevananther

Faculty, Staff and Students Publications

The liver plays a significant role in regulating a wide range of metabolic, homeostatic, and host-defense functions. However, the impact of liver injury on the host's ability to control bacteremia and morbidity in sepsis is not well understood. Leukocyte recruitment and activation lead to cytokine and chemokine release, which, in turn, trigger hepatocellular injury and elevate nucleotide levels in the extracellular milieu. P2Y2 purinergic receptors, G protein-coupled and activated by extracellular ATP/UTP, are expressed at the cell surface of hepatocytes and nonparenchymal cells. We sought to determine whether P2Y2 purinergic receptor function is necessary for the maladaptive host response to …


Delays In Hepatitis B Immunization Series Completion In People With Human Immunodeficiency Virus, Daanish Sheikh, Kristen A Staggers, Jennifer Carey, Wendy A Keitel, Robert L Atmar, Hana M El Sahly, Jennifer A Whitaker Nov 2023

Delays In Hepatitis B Immunization Series Completion In People With Human Immunodeficiency Virus, Daanish Sheikh, Kristen A Staggers, Jennifer Carey, Wendy A Keitel, Robert L Atmar, Hana M El Sahly, Jennifer A Whitaker

Faculty, Staff and Students Publications

BACKGROUND: Studies have demonstrated low hepatitis B virus (HBV) vaccine series completion among persons with human immunodeficiency virus (HIV).

METHODS: We conducted a retrospective record review of persons entering HIV care at 2 clinics in Houston, Texas, between 2010 and 2018. Kaplan-Meier curves summarized time to receipt of HBV vaccines for those eligible for vaccination. We estimated the proportions of patients who had received 1, 2, or 3 HBV vaccine doses at 12 and 24 months after entry to care. A Prentice Williams and Peterson total time model was used to evaluate associations between patient characteristics and time to vaccination. …


P2y2 Purinergic Receptor Gene Deletion Protects Mice From Bacterial Endotoxin And Sepsis-Associated Liver Injury And Mortality, Athis R Arunachalam, Sanju S Samuel, Arunmani Mani, Janielle P Maynard, Kelsey M Stayer, Eric Dybbro, Subapradha Narayanan, Aalekhya Biswas, Saliha Pathan, Krishnakant Soni, Abu Hena Mostafa Kamal, Chandra Shekar R Ambati, Nagireddy Putluri, Moreshwar S Desai, Sundararajah Thevananther Nov 2023

P2y2 Purinergic Receptor Gene Deletion Protects Mice From Bacterial Endotoxin And Sepsis-Associated Liver Injury And Mortality, Athis R Arunachalam, Sanju S Samuel, Arunmani Mani, Janielle P Maynard, Kelsey M Stayer, Eric Dybbro, Subapradha Narayanan, Aalekhya Biswas, Saliha Pathan, Krishnakant Soni, Abu Hena Mostafa Kamal, Chandra Shekar R Ambati, Nagireddy Putluri, Moreshwar S Desai, Sundararajah Thevananther

Faculty, Staff and Students Publications

Prostate cancer (PCa) remains a leading cause of mortality among American men, with metastatic and recurrent disease posing significant therapeutic challenges due to a limited comprehension of the underlying biological processes governing disease initiation, dormancy, and progression. The conventional use of PCa cell lines has proven inadequate in elucidating the intricate molecular mechanisms driving PCa carcinogenesis, hindering the development of effective treatments. To address this gap, patient-derived primary cell cultures have been developed and play a pivotal role in unraveling the pathophysiological intricacies unique to PCa in each individual, offering valuable insights for translational research. This review explores the applications …


State-Of-The-Art Document On Optimal Contemporary Management Of Cardiomyopathies, Petar M Seferović, Marija Polovina, Giuseppe Rosano, Biykem Bozkurt, Marco Metra, Stephane Heymans, Wilfried Mullens, Johann Bauersachs, Karen Sliwa, Rudolf A De Boer, Dimitrios Farmakis, Thomas Thum, Iacopo Olivotto, Claudio Rapezzi, Aleš Linhart, Domenico Corrado, Carsten Tschöpe, Ivan Milinković, Antoni Bayes Genis, Gerasimos Filippatos, Andre Keren, Milika Ašanin, Gordana Krljanac, Ružica Maksimović, Hadi Skouri, Tuvia Ben Gal, Brenda Moura, Maurizio Volterrani, Magdy Abdelhamid, Yuri Lopatin, Ovidiu Chioncel, Andrew J S Coats Nov 2023

State-Of-The-Art Document On Optimal Contemporary Management Of Cardiomyopathies, Petar M Seferović, Marija Polovina, Giuseppe Rosano, Biykem Bozkurt, Marco Metra, Stephane Heymans, Wilfried Mullens, Johann Bauersachs, Karen Sliwa, Rudolf A De Boer, Dimitrios Farmakis, Thomas Thum, Iacopo Olivotto, Claudio Rapezzi, Aleš Linhart, Domenico Corrado, Carsten Tschöpe, Ivan Milinković, Antoni Bayes Genis, Gerasimos Filippatos, Andre Keren, Milika Ašanin, Gordana Krljanac, Ružica Maksimović, Hadi Skouri, Tuvia Ben Gal, Brenda Moura, Maurizio Volterrani, Magdy Abdelhamid, Yuri Lopatin, Ovidiu Chioncel, Andrew J S Coats

Faculty, Staff and Students Publications

Cardiomyopathies represent significant contributors to cardiovascular morbidity and mortality. Over the past decades, a progress has occurred in characterization of the genetic background and major pathophysiological mechanisms, which has been incorporated into a more nuanced diagnostic approach and risk stratification. Furthermore, medications targeting core disease processes and/or their downstream adverse effects have been introduced for several cardiomyopathies. Combined with standard care and prevention of sudden cardiac death, these novel and emerging targeted therapies offer a possibility of improving the outcomes in several cardiomyopathies. Therefore, the aim of this document is to summarize practical approaches to the treatment of cardiomyopathies, which …


Untargeted Metabolomic Analysis Investigating Links Between Unprocessed Red Meat Intake And Markers Of Inflammation, Alexis C Wood, Goncalo Graca, Meghana Gadgil, Mackenzie K Senn, Matthew A Allison, Ioanna Tzoulaki, Philip Greenland, Timothy Ebbels, Paul Elliott, Mark O Goodarzi, Russell Tracy, Jerome I Rotter, David Herrington Nov 2023

Untargeted Metabolomic Analysis Investigating Links Between Unprocessed Red Meat Intake And Markers Of Inflammation, Alexis C Wood, Goncalo Graca, Meghana Gadgil, Mackenzie K Senn, Matthew A Allison, Ioanna Tzoulaki, Philip Greenland, Timothy Ebbels, Paul Elliott, Mark O Goodarzi, Russell Tracy, Jerome I Rotter, David Herrington

Faculty, Staff and Students Publications

BACKGROUND: Whether red meat consumption is associated with higher inflammation or confounded by increased adiposity remains unclear. Plasma metabolites capture the effects of diet after food is processed, digested, and absorbed, and correlate with markers of inflammation, so they can help clarify diet-health relationships.

OBJECTIVE: To identify whether any metabolites associated with red meat intake are also associated with inflammation.

METHODS: A cross-sectional analysis of observational data from older adults (52.84% women, mean age 63 ± 0.3 y) participating in the Multi-Ethnic Study of Atherosclerosis (MESA). Dietary intake was assessed by food-frequency questionnaire, alongside C-reactive protein (CRP), interleukin-2, interleukin-6, fibrinogen, …


Site-Specific Pathophysiology In A Neonatal Mouse Model Of Gastroparesis, Price T Edwards, Krishnakant G Soni, Margaret E Conner, Stephanie W Fowler, Jaime P P Foong, Rhian Stavely, Lily S Cheng, Geoffrey A Preidis Nov 2023

Site-Specific Pathophysiology In A Neonatal Mouse Model Of Gastroparesis, Price T Edwards, Krishnakant G Soni, Margaret E Conner, Stephanie W Fowler, Jaime P P Foong, Rhian Stavely, Lily S Cheng, Geoffrey A Preidis

Faculty, Staff and Students Publications

BACKGROUND: Early-life events impact maturation of the gut microbiome, enteric nervous system, and gastrointestinal motility. We examined three regions of gastric tissue to determine how maternal separation and gut microbes influence the structure and motor function of specific regions of the neonatal mouse stomach.

METHODS: Germ-free and conventionally housed C57BL/6J mouse pups underwent timed maternal separation (TmSep) or nursed uninterrupted (controls) until 14 days of life. We assessed gastric emptying by quantifying the progression of gavaged fluorescein isothiocyanate (FITC)-dextran. With isolated rings of forestomach, corpus, and antrum, we measured tone and contractility by force transduction, gastric wall thickness by light …


Editorial: Respiratory Microbiome In Health And Disease, Yimin Zhuang, Tao Ding, Jiangchao Zhao, Jianmin Chai Nov 2023

Editorial: Respiratory Microbiome In Health And Disease, Yimin Zhuang, Tao Ding, Jiangchao Zhao, Jianmin Chai

Animal Science Faculty Publications and Presentations

Editorial on the Research Topic:

Respiratory microbiome in health and disease


Using Biometrics, Behavioral Observations, And Multiple Molecular Techniques To Assess The Impacts Of Changes In Temperature And Salinity On The Common Bay Mussel (Mytilus Trossulus), Casey Martin Nov 2023

Using Biometrics, Behavioral Observations, And Multiple Molecular Techniques To Assess The Impacts Of Changes In Temperature And Salinity On The Common Bay Mussel (Mytilus Trossulus), Casey Martin

Dissertations and Theses

The intertidal zone is a place of rapid and frequent change that is home to a variety of creatures who are essential to the integrity of the habitat. Mussels are robust sessile bivalves that anchor to the rocks of the intertidal. The prominent species on the Oregon Coast, the Common Bay Mussel (Mytilus trossulus), plays an essential role as a coastal food source, water column filter, and barrier to prevent erosion due to wave action. Mytilus trossulus withstands daily shifts in temperature, salinity, and tide, as well as seasonal changes. Global climate change due to excess carbon emissions …


Advocacy Spotlight: Important: State Issues Changes To Delegation Of Duties Rules, Neema Katibai Jd Nov 2023

Advocacy Spotlight: Important: State Issues Changes To Delegation Of Duties Rules, Neema Katibai Jd

The Journal of the Michigan Dental Association

The Michigan Board of Dentistry has introduced changes to the rules governing the delegation of duties to dental auxiliaries, including the reclassification of "dental assistants" (those not formally trained or licensed) as "unregistered dental auxiliaries" (UDAs). The classification Registered Dental Assistant (RDA) remains. Changes involve the supervision levels for specific tasks and guiding training UDAs for orthodontic duties. Notable changes include allowing UDAs to perform certain orthodontic tasks and expanding their scope of work to include duties such as taking impressions, polishing, and providing nutritional counseling. Dental professionals should know these changes and the supervision required for delegation to UDAs …