Digital Commons Network^™

The Role Of Vitamin B9 In Modulating Autism Symptoms In Children, Sarah Roeser

Department of Nutrition Student Projects

The prevalence of Autism spectrum disorder (ASD) has risen significantly over the past five decades, now affecting approximately 1 in 31 children. This literature review examined whether folinic acid, compared with other forms of vitamin B9 (synthetic folic acid, dietary folate, and 5-methyltetrahydrofolate), modulates ASD symptoms including verbal communication, motor skills and social interaction, particularly in children positive for folate receptor alpha autoantibodies (FRAAs). A thorough search of PubMed, Google Scholar, Nature, and ScienceDirect, primarily from 2015–2026, identified five randomized controlled trials (RCTs) and one meta-analysis evaluating folinic acid at standardized doses of 2 mg/kg/day with a maximum dose of …

Implementing A Nutrition Screening, Education, And Risk Reduction Framework In Optometric Care To Prevent Diabetic Retinopathy In Adults With T2dm, Juliana M. Varanelli

Department of Nutrition Student Projects

Diabetic retinopathy (DR) is a leading cause of preventable vision loss among adults with Type 2 diabetes mellitus (T2DM), driven largely by chronic hyperglycemia, oxidative stress, and inflammation. Despite strong evidence supporting the role of nutrition in modifying these risk factors, nutrition screening and counseling are not routinely integrated into optometric care. This project aimed to develop a practical, evidence-based framework to incorporate nutrition screening, patient education, and referral pathways into comprehensive optometric practice to support prevention and reduce the onset and progression of diabetic retinopathy.

This project involved a literature review of peer-reviewed research and clinical guidelines related to …

The Price Of Democracy: How Federal Tax Receipts Can Enhance Public Awareness, Transparency, And Civic Discourse, Hannah Bordeau

Honors Theses

Each year, the IRS collects roughly $2.18 trillion in income taxes alone, accounting for approximately 48% of the government's total revenue. However, the IRS does not audit individual tax receipts for citizens, preventing them from seeing a visual breakdown of where their money is allocated. To better understand how citizens feel about governmental spending, this project will utilize a mixed-methods approach, incorporating a qualitative case study to explore the developments (or lack thereof) regarding a “tax receipt” and conducting interviews to gain insights into public perception of a tax receipt program. In addition to the interviews, this project will explore …

Heavy Metal, Heavy Costs: Soil Copper Contamination Undermines Bee Communities In Urban Agriculture, Penelope Fisher

Honors Theses

As city populations grow, the need for fresh produce in cities to feed people also grows. One such growing urban environment is Dayton, Ohio, which has begun to implement measures aiming to limit the hunger experienced by underserved individuals in the city. According to The Dayton Food Bank, in Montgomery County alone 14.2% of individuals living in the county experience food insecurity, a majority of whom are children. Urban farming has proven to be a lucrative solution to some of these issues. However, these farms are often established in areas where the soil is degraded due to previous land use, …

Ai-Driven Computer Vision For Automated Ripeness Detection In Tomato Plants, Austin Ebbing

Honors Theses

This work presents a computer vision-based approach for automated ripeness detection in tomato plants. The system leverages a YOLOv8 segmentation model trained on a publicly available dataset to detect and isolate individual tomatoes within complex visual environments. While segmentation provides an initial estimate of tomato regions, additional processing is required to remove non-fruit artifacts such as stems and leaves that may interfere with analysis. To address this, an edge-constrained region growing method is used to tighten segmentation masks by removing unwanted structures such as stems and leaves while preserving the underlying fruit. Ripeness is then estimated using a color-based analysis …

Evaluating The Impact Of Positional Isometric Contractions On Upper-Body Strength In Adolescent Athletes, Maurice Harden

Doctorate in Kinesiology

This study examined the effects of positional isometric contractions used as a pre-exercise warm-up on upper-body strength in adolescent male athletes. Twenty participants were randomly assigned to either a positional isometric group or a positional stretching group. Peak isometric force was measured using the VALD Force Decks System across three consecutive testing sessions. Data were analyzed using a three-week by two-group mixed design analysis of variance. The results showed no statistically significant differences between warm-up methods or across testing sessions. However, the positional isometric group demonstrated slightly higher initial force values that leveled out with repeated testing. These findings suggest …

Development Of A Survey For Assessing Women’S Perceptions Of Weight-Related Side Effects Of Hormonal Contraceptives, Ayla Mae Laro

Theses

Background —Hormonal contraceptives (HCs) are widely used among reproductive-age women, yet concerns about weight gain remain common and are frequently cited as a reason for dissatisfaction or discontinuation. Dissatisfaction and discontinuation of HCs can lead to unintended pregnancy—a serious health concern in the United States. Existing research has largely focused on objectively measured weight change as a secondary outcome rather than on perceptions of weight-related side effects, and no validated tool currently assesses these perceptions. Additionally, studies have historically failed to include women with overweight and obesity. This cross-sectional mixed-methods study developed and face-validated an online survey measuring reproductive-age women’s …

Anthropometric And Lifestyle Metrics Compared In Postmenopausal Women, Amanda Louise Daniel

Theses

Background: Hormone changes and aging that lead to menopause have a significant impact on quality of life. Understanding health thresholds for the components of body composition in this population are not well known. The relationship between menopausal symptoms and lifestyle factors is understudied. Methods: A mixed-methods approach included surveys and face-to-face body composition analysis using bioelectric impedance. Eating competence, sleep quality, and physical activity were assessed online with validated surveys prior to body composition measurement. Data were transformed to normality and analyzed with Pearson correlation coefficients and independent t-test correcting for multiple comparisons. Results Of the 69 interested people, 50 …

Hepatoprotective Effect Of Solanum Lycopersicum Extract Against High-Fat Diet-Induced Liver Injury In Rats, Rista Dwi Hermilasari, Harry Allan Papendang

Sultan Qaboos University Medical Journal

Objectives: A high-fat diet (HFD) can trigger liver disease, one of which is non-alcoholic fatty liver disease (NAFLD). This study aimed to examine the effect of Solanum lycopersicum extract on liver protection, namely macroscopic and microscopic aspects and liver weight in high-fat diet model rats. Methods: This true experimental study used male Wistar rats divided into a normal (control) group, HFD group and HFD group with S. lycopersicum extract (HFD-SL). This study was conducted from May to November 2024 at the Faculty of Dentistry Laboratory Universitas Jember, Jember, East Java, Indonesia. After the intervention, the weight of the rats' livers …

Spartan Daily, April 22, 2026, San Jose State University, School Of Journalism And Mass Communications

Spartan Daily, 2026

Volume 166, Issue 36

Wherefore The Magic? The Evolutionary Role Of Psilocybin In Nature, K. J. Matthews Nicholass, I. Flis, M. E. Hanley, M. E. Knight, S. M. Lane, G. Littlejohn, M. D.F. Thom, R. A. Billington, R. Boden, R. Cummins, B. J. Green, C. Griffin, S. Jones, D. Salmon, I. Sleep, N. Smirnoff, J. S. Ellis

School of Biological and Marine Sciences

Research into psychedelic compounds is in resurgence because of the exciting potential for their use in the treatment of psychiatric and mental health disorders. Despite this revival, remarkably little is known about their evolution. One of the most intriguing psychedelic compounds is psilocybin, the compound found in ‘magic’ mushrooms and used in ritual ceremonies in North America for generations. Associated with agaricomycete fungi across eight distantly related genera, psilocybin acts in a similar way to the neurotransmitter serotonin, yet how and why natural selection favoured its biosynthesis remains unclear. Given the resemblance to serotonin, a highly conserved neurotransmitter across invertebrates …

Exercise As A Non-Pharmacological Intervention For The Prevention And Delay Of Alzheimer’S Disease And Dementia, Eden Culver

Honors Theses

Alzheimer’s disease (AD) and related dementias are rapidly increasing public health concerns due to aging populations and rising life expectancy. Alzheimer’s disease is characterized by progressive neurodegeneration associated with amyloid-β plaques, tau neurofibrillary tangles, neuroinflammation, oxidative stress, and neuronal loss, leading to impairments in memory, cognition, and daily functioning. Because there is currently no cure for Alzheimer’s disease, identifying effective non-pharmacological prevention strategies is essential. This paper examines the role of physical exercise as a preventive and protective intervention for delaying the onset and progression of Alzheimer’s disease and dementia. Current research demonstrates that exercise supports brain health through several …

Icsb Poster Session, Ikhlas Khan

Oxford ICSB

Poster abstracts from the ICSB 2026 poster session.

Metabolomic Characterizations Of Hericium Erinaceus (Bull.) Pers. And Laricifomes Officinalis (Vill.) Kotl. & Pouzar Fungal Cultures, Kyle Meyer

Oxford ICSB

We present metabolomic characterizations of Hericium erinaceus (Bull.) Pers. (lion’s mane, yamabushitake, etc.), and Laricifomes officinalis (Vill.) Kotl. & Pouzar (syn. Fomitopsis officinalis; agarikon, eburiko, etc.) fungal cultures by high resolution orbitrap mass spectrometry and HPLC-DAD. Primary focus has been applied to the cultivation of these species on brown rice, Oryza sativa L., as a solid substrate.   In the case of H. erinaceus, we have observed key differences in lipid metabolite profiles over a 28-day fermentation time series suggesting possible grain lipid feedstocks for fungal-derived lipid production, providing clear evidence of substrate biotransformation.   For L. officinalis cultures, we observe distinct …

Bioactive Metabolite Markers For Functional Mushrooms: Comprehensive Metabolomic Mapping Of Full-Spectrum Cultivated Mushrooms, Standard Production And Method Development., Julie Daoust, Ivana Blaženović

Oxford ICSB

Functional mushrooms are increasingly used in dietary supplements and functional foods, yet current scientific characterization of their chemistry remains limited by narrow extraction paradigms, limited standards availability and incomplete databases. In 2025, M2 Ingredients, in collaboration with Adikai Insights, completed a metabolomics atlas, a comprehensive untargeted metabolomics investigation of ten cultivated mushroom species grown under controlled indoor conditions in and effort to identify known bioactive molecules in whole mushroom samples to guide standard and quantitative method development targeting bioactive compounds present in the materials.   Using high-resolution mass spectrometry and advanced cheminformatics, a total of 5,139 unique functional mushroom metabolites were …

Authenticated Hericium Erinaceus Mushroom And Selected Mycelia Reference Materials For General Industry Use, Steven Dentali

Oxford ICSB

The establishment of authenticated reference materials is critical for method validation, standards development, and adulteration detection in the medicinal mushroom market. Hericium erinaceus (Lion’s Mane) is widely commercialized, yet historically has lacked species-specific analytical standards. This presentation describes the species identification protocol used by Nammex to develop and maintain authenticated H. erinaceus mushroom reference materials that support ongoing standards work, including advisory contributions to AOAC INTERNATIONAL initiatives. Production partner voucher specimens are authenticated using macroscopic, organoleptic, and morphological examination by qualified personnel, and retained as internal reference materials. Genetic verification using DNA sequencing confirms H. erinaceus identity in voucher specimens …

Determination Of Kratom Alkaloids In Botanical Products Using Multi-Criteria Lc–Ms Analysis, Mengliang Zhang

Oxford ICSB

Kratom (Mitragyna speciosa) is a botanical product widely sold in the United States as powders, capsules, tablets, gummies, and beverages. Natural kratom leaves primarily contain mitragynine (MG) as the dominant alkaloid. However, an increasing number of commercial products contain elevated levels of the more potent opioid alkaloid 7-hydroxymitragynine (7-OH) and the semi-synthetic compound mitragynine pseudoindoxyl (MGP). Reliable analytical identification of these compounds is critical for dietary supplement testing, regulatory monitoring, and public health protection. However, kratom matrices contain numerous structurally related alkaloids and isomeric compounds that complicate mass spectrometric identification and may lead to false positive assignments. The objective of …

Do Omega-3 Supplements Reduce Pain And Symptom Severity In Primary Dysmenorrhea, Kristen Werner

Liberty University Research Week

Background: Primary Dysmenorrhea is a gynecological condition that affects many women worldwide. It is characterized by painful menstrual cramping and can result in decreased quality of life. Omega 3 fatty acid supplements have been proposed as an alternative treatment method to reduce severity of dysmenorrhea.

Methods: The Prisma method was used to conduct an integrative literature review of Pub Med, EBSCO, and Google Scholar Databases.

Results: Omega 3 fatty acid supplementation has been shown to reduce dysmenorrhea pain and severity.

Conclusions: Omega 3 supplementation is a viable alternative to conventional treatments methods for dysmenorrhea. This is ideal for women who …

A Patient-Centered Framework For Overcoming Barriers In Tuberculosis Care, Owen Newman, Ethan Jerome, John Meade

Liberty University Research Week

Tuberculosis (TB) remains the world’s deadliest infectious disease, yet it is both preventable and curable. The disease disproportionately affects populations living in poverty, with significant global impact:

1.23 million deaths in 20241

10.7 million new infections globally1

80%+ of cases in low- and middle-income countries1

~50% of TB households face costs >20% of income1,2

This study argues that TB persists due to social determinants, such as poverty, malnutrition, and stigma, rather than medical limitations alone. We propose a three-domain framework that maps where standard medical care fails the individual: systemic infrastructure, economic burden, and psychosocial isolation. By addressing these three …

The Cost Of Cargo Preference: How Shipping Requirements Hinder Food Aid Efficiency, Grace Pattara

Liberty University Research Week

No abstract provided.

Genotype-Dependent Cardiac Responses To Caffeine: Acute Electrocardiographic Effects Across Cyp1a2 Gene Variants, Ethan Pedersen

Liberty University Research Week

It is estimated that approximately 70% of individuals worldwide consume caffeine daily. A plethora of genes contribute to caffeine metabolism, out of which CYP1A2 is responsible for 90%. Two prominent CYP1A2 alleles are *1A and *1F which metabolize caffeine at fast and slow rates respectively. Retrospective research has demonstrated *1F possessing individuals are at an increased risk for nonfatal myocardial infarction. However, the acute electrocardiographic and physiological cardiac responses to caffeine across a range of doses remain poorly characterized. The goal of the proposed study is to evaluate the physiological changes of the heart, using an ECG, in individuals who …

Vitamin D Relation To Bone Mineral Density In Female Athletes: Critically Appraised Topic, Baylee Klindworth

Liberty University Research Week

Background: Vitamin D is important for overall bone health, muscle function, and injury prevention, especially in female athletes who may be at risk for vitamin D deficiency that are limited to sunlight exposure, high training demands, and dietary intake. In young female athletes and adults, the relationship between vitamin D and bone mineral density (BMD) is not clear. The purpose of this critically appraised topic is to review current evidence on the relationship between vitamin D levels and bone health in female athletes and adults. Methods: Four cross-sectional studies were included: Fields et al., Brännström et al., Lim et al., …

Geographic Variation In Cardiometabolic And Nutrition-Related Health Indicators Across Rural Communities In Guatemala And Honduras, Grace Sibert

Liberty University Research Week

Chronic diseases and nutritional deficiencies are increasing public health concerns in rural and underserved communities in Central America, where limited access to preventive care and routine health screening contributes to undiagnosed risk. This study examined the prevalence and geographic distribution of cardiometabolic and nutrition-related health indicators across rural communities in Guatemala and Honduras. We conducted a cross-sectional analysis of community health screening data collected from 2021 and 2023–2025. Measurements included body mass index (BMI), blood glucose, hemoglobin, and blood pressure. Overweight was defined as BMI 25.0–29.9, obesity as BMI =30, elevated blood glucose as =140 mg/dL, hypertension as systolic =140 …

4-H Award Program

Warren C. Cowen Papers

Tarrant County 4-H award program for state 4-H winners Sandra Newton, Joe Spears, Tommy Lutes and Patricia Stephenson, November 13, 1961.

Icu Decision Tool Impact On Rebound Hyperglycemia, Daniel J. Donovan, Emily Highsmith, Sonya Khan, Michelle Horng

Advances in Cancer Education and Quality Improvement

Hyperglycemia, defined as a blood glucose level ≥180 mg/dL in the hospitalized patient, is linked to negative outcomes including longer hospital stays, increased infection risk, and higher morbidity and mortality rates. In addition to critically ill patients with diabetes, hyperglycemia can develop in individuals without diabetes due to factors such as steroid use, continuous tube feedings, and an elevated stress response. Patients who have uncontrolled hyperglycemia are often placed on continuous insulin infusions (CII), but rebound hyperglycemia frequently occurs after CII discontinuation if the maintenance insulin regimen (MIR) is insufficient. Implementation of a MIR decision support tool integrated within an …

Advancements In Extraction And Co-Extraction Of Botanicals For Standardization And Efficacy, Rory Coleman

Oxford ICSB

Historically, botanicals have served human health in traditional medicine and supplementation due to their bioactive components. Efficient, clean extractions and clinical validation have become fundamental technologies, rendering access to libraries of efficacious products. However, cost, regulatory status, and speed to market have kept many botanicals in single or simple form. Mixtures of such single botanical extracts often require large quantities for effect, influenced by chemical composition, concentration, and delivery format. During the extraction and concentration process, exogenous "bioenhancers," e.g. piperine or oil blends for hydrophilic molecules, often become a necessity, exasperating the problem.   Here, we will delve into the development …

2026 Conference Program, Georgia Southern University

GS4 Student Scholars Symposium

Conference Program

Yeast As A "Microbial Factory", Kaila Fuller, Betsy Jean Yakes

Oxford ICSB

Yeast are eukaryotic, single-celled microorganisms that are members of Kingdom Fungi, and in the world of dietary supplements, yeast qualify as a dietary ingredient as a botanical. During fermentation, yeast naturally produce byproducts that can be harvested, purified, and sold in a dietary supplement. Advances in biotechnology have allowed for genetic modification of yeast so that yeast can produce large quantities of native or non-native constituents during fermentation, effectively making yeast a “microbial factory” for various chemicals. Chemicals produced this way can qualify as a dietary ingredient as a constituent of a botanical. Relevant examples of past submitted notifications (public …

Probabilistic User Intent Modeling Based On Time-Window Gaze Analysis, John D. Hurwitz, Yaaseen Mahomed

Defensive Publications Series

ABSTRACT

A single-shot gaze vector often fails to accurately reflect user intent during multimodal queries due to saccadic noise, visual competition in dense environments, and the temporal lag between visual fixation and vocalization. This disclosure describes a method for multimodal query disambiguation using a temporal gaze buffer that maintains a rolling history of gaze vectors. After receiving a query, a probabilistic spatial-temporal heatmap can be generated from the buffered data. This heatmap represents attention density over a variable time window, which may be adjusted based on the query context or environmental classifications. To identify specific objects of interest, image frames …

Scientific Research In Cuba: A General Analysis With A Special Focus On Energy, Agriculture And Technology, Henri Dou, Pierre Fournie

International Journal of Islands Research

An analysis of science in Cuba is carried out using data from the OpenAlex database. Examples are developed: agriculture, rice, technology in relation to the current situation: national food supply, energy and medicine. The predominance of research in biology and medicine and the low commitment in the fields of agriculture, energy, medicinal plants and technology are highlighted. Various development schemes are proposed. The conclusion is that research must be directed towards strategic areas: food and energy, must be less dispersed and that technology must be better taken into account. Three proposals are made: the development of a chemical analysis platform …