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Articles 26071 - 26100 of 241284
Full-Text Articles in Entire DC Network
Maternal Mortality: What Is The Situation And The Determinants?, Taqi Mohammed Jwad Taher
Maternal Mortality: What Is The Situation And The Determinants?, Taqi Mohammed Jwad Taher
Maaen Journal for Medical Sciences
Maternal mortality is a term used to describe a woman's death due to a pregnancy-related issues during pregnancy or a year from its termination or due to an existing condition exacerbated by pregnancy. Every year, an estimated 303,000 women lose their lives during childbirth, mostly in underdeveloped nations. This study aimed to assess the current situation and causes of maternal mortality around the world. It was conducted by searching for the related keywords in Google Scholar, ResearchGate, and Google Books. The search was limited to articles published between the years 2015 and 2023. This article found that maternal deaths can …
Development Of Yoghurt Incorporated With Beetroot Puree And Its Effect On The Physicochemical Properties And Consumer Acceptance, Mercia Lionel Adjei, Abena Boakye, Godwin Deku, Nana Baah Pepra-Ameyaw, Antoinette Simpah Anim Jnr, Ibok Nsa Oduro, William Otoo Ellis
Development Of Yoghurt Incorporated With Beetroot Puree And Its Effect On The Physicochemical Properties And Consumer Acceptance, Mercia Lionel Adjei, Abena Boakye, Godwin Deku, Nana Baah Pepra-Ameyaw, Antoinette Simpah Anim Jnr, Ibok Nsa Oduro, William Otoo Ellis
Food Science Faculty Articles and Research
Background
Yoghurt is one of the most popularly consumed fermented products which provides several nutritional benefits. Yoghurt products often include flavour and colour additives however, growing awareness of the risks associated with synthetic food additives has necessitated the need to explore more natural colour and flavour as food additives.
Methods
This study evaluated the effect of beetroot puree as flavouring and colourant in yoghurt production and quality. To develop the yoghurt product, incubation time and proportion of beetroot puree were optimized based on the resulting pH, titratable acidity, colour, and viscosity using response surface methods.
Results
Optimum yoghurt formulations were …
Predicting Sedentarism And Its Impact On Caloric Requirements, Jacob Michels, John C. Beghin
Predicting Sedentarism And Its Impact On Caloric Requirements, Jacob Michels, John C. Beghin
Yeutter Institute International Trade Policy Review
A recent study conducted by PhD candidate Jacob Michels and Agricultural economist John Beghin delves into the question of whether global estimates of food insecure populations need a reevaluation of their methodology to account for increasing sedentarism. This reevaluation is prompted by the increasing prevalence of sedentary lifestyles worldwide, which calls for a redefinition of caloric thresholds indicating the onset of food insecurity. In this short article, we provide a nontechnical summary of their investigation recently published in Michels and Beghin (2024).
Exploring Referral And Service Utilization Patterns Within An Outpatient Interdisciplinary Pediatric Chronic Pain Program, Aimee Hildenbrand, Christina M Amaro, Benjamin Bear, Catherine Soprano, Katherine S Salamon
Exploring Referral And Service Utilization Patterns Within An Outpatient Interdisciplinary Pediatric Chronic Pain Program, Aimee Hildenbrand, Christina M Amaro, Benjamin Bear, Catherine Soprano, Katherine S Salamon
Department of Medicine Faculty Papers
PURPOSE: We examine referral sources and clinical characteristics for youth presenting to an outpatient interdisciplinary pediatric chronic pain program.
PATIENTS AND METHODS: Referral data were extracted from the electronic health record. PROMIS Pediatric Anxiety and Pain Interference Scales were administered at an initial evaluation visit.
RESULTS: The program received 1488 referrals between 2016 and 2019, representing 1338 patients, with increasing volume of referrals over time. Referrals were primarily from orthopedics (19.6%), physical medicine and rehabilitation (18.8%), neurology (14.4%), and rheumatology (12.6%). Patients referred were primarily female (75.4%), White (80.1%), English-speaking (98.4%) adolescents (median=15.0 years). Of those referred, 732 (54.7%) attended …
Visual Methods For Qualitative Research With Older Refugees: Reflection On Strengths And Drawbacks, Prince Chiagozie Ekoh, Christine A. Walsh
Visual Methods For Qualitative Research With Older Refugees: Reflection On Strengths And Drawbacks, Prince Chiagozie Ekoh, Christine A. Walsh
The Qualitative Report
Although older refugees have similar characteristics and vulnerabilities as other populations that have benefited from visual research methods, there is scarce evidence of these methods being used for qualitative social work studies with older refugees. In this article, we discuss the application of visual methods for social work research with older refugees for a better understanding of their experiences and challenges, highlighting how it can be evocative, improve discussions by reaching senses that ordinary interviews cannot grasp, avoid re-traumatisation during research, and build resilience and coping in older refugees. We propose that visual methods could address power dynamics that privilege …
February 2, 2024 Ereporter, University Of Alabama At Birmingham
February 2, 2024 Ereporter, University Of Alabama At Birmingham
eReporter (campus newsletter)
No abstract provided.
Characteristics And Patterns Of Diagnoses For Patients Admitted From And Discharged To Court Or Law Enforcement In The State Of Florida, Christopher Bridgeman
Characteristics And Patterns Of Diagnoses For Patients Admitted From And Discharged To Court Or Law Enforcement In The State Of Florida, Christopher Bridgeman
MUSC Theses and Dissertations
OBJECTIVE: The role of prison healthcare is to provide safe, high-quality, and timely healthcare for prisoners. This study examines the characteristics of patients discharged from healthcare in the nation’s third-largest prison system, the state of Florida.
METHODS: This was a study of adults (18-64) admitted from or discharged to law enforcement agencies in Florida in 2018 for healthcare in Florida hospitals. Patients were divided among distinguishable characteristics of gender, zip code, income quartile, rural/urban locality, and insurance type. Data was collected within the Office of Data Collection & Quality Assurance (DCQA) within the Florida Agency for Health Care Administration (Florida …
Female Breast Cancer Survivor’S Perspective Of Support Systems In Trinidad And Tobago, Andrea Mcdonald, Isabella Granderson, Olivia Johnson, Antoinette W. Coward, Brendon Bhagwandeen
Female Breast Cancer Survivor’S Perspective Of Support Systems In Trinidad And Tobago, Andrea Mcdonald, Isabella Granderson, Olivia Johnson, Antoinette W. Coward, Brendon Bhagwandeen
The Journal of the Research Association of Minority Professors
Globally, breast cancer is the most common cancer affecting women. The Cancer Registry of Trinidad and Tobago indicated that 45.9% of the breast cancer cases belonged to the African ethnicity, 27.5% Asian Indian, and 14.7% mixed ethnicity. Research on female breast cancer survivors' perspectives on support systems and care within the Caribbean region is limited. Therefore, this study aims to examine female breast cancer survivors' perspective of support systems in Trinidad and Tobago. We conducted a cross-sectional study with 74 cancer survivors attending support groups. To be eligible, the participants had to be females 18 years or older, residents of …
Food And Mood: The Correlation Between Vitamin B12 And Folate Intake And Depression, Jana Soucar, Hawley Almstedt
Food And Mood: The Correlation Between Vitamin B12 And Folate Intake And Depression, Jana Soucar, Hawley Almstedt
Honors Thesis
Vitamin B12 is an essential nutrient that metabolizes homocysteine, which is a potentially neurotoxic molecule when in excess. Folate is a B vitamin that is essential to the production of norepinephrine, serotonin, and dopamine in the brain. Studies show that a deficiency in vitamin B12, as well as folate, may be associated with mental health conditions. Additionally, the prevalence of depression is higher in college students than other demographic populations. PURPOSE: The purpose of this study was to investigate a correlation between vitamin B12 and folate intake with signs and symptoms of depression in college students. METHODS: This …
Nature Of The Evidence Base And Approaches To Guide Nutrition Interventions For Individuals: A Position Paper From The Academy Of Nutrition Sciences, Mary Hickson, Constantina Papoutsakis, Angela M. Madden, Mary Anne Smith, Kevin Whelan
Nature Of The Evidence Base And Approaches To Guide Nutrition Interventions For Individuals: A Position Paper From The Academy Of Nutrition Sciences, Mary Hickson, Constantina Papoutsakis, Angela M. Madden, Mary Anne Smith, Kevin Whelan
School of Health Professions
This Position Paper from the Academy of Nutrition Sciences is the third in a series which describe the nature of the scientific evidence and frameworks that underpin nutrition recommendations for health. This paper focuses on evidence which guides the application of dietary recommendations for individuals. In some situations, modified nutrient intake becomes essential to prevent deficiency, optimise development and health, or manage symptoms and disease progression. Disease and its treatment can also affect taste, appetite and ability to access and prepare foods, with associated financial impacts. Therefore, the practice of nutrition and dietetics must integrate and apply the sciences of …
The Rider (2024-02-02), Natalie Lapsley
Targeting Prostate Tumor Low-Molecular Weight Tyrosine Phosphatase For Oxidation-Sensitizing Therapy, Stephanie M Stanford, Tiffany P Nguyen, Joseph Chang, Zixuan Zhao, G Lavender Hackman, Eugenio Santelli, Colton M Sanders, Madhusudhanarao Katiki, Eleonora Dondossola, Brooke L Brauer, Michael A Diaz, Yuan Zhan, Sterling H Ramsey, Philip A Watson, Banumathi Sankaran, Claudia Paindelli, Vanessa Parietti, Antonios G Mikos, Alessia Lodi, Aditya Bagrodia, Andrew Elliott, Rana R Mckay, Ramachandran Murali, Stefano Tiziani, Arminja N Kettenbach, Nunzio Bottini
Targeting Prostate Tumor Low-Molecular Weight Tyrosine Phosphatase For Oxidation-Sensitizing Therapy, Stephanie M Stanford, Tiffany P Nguyen, Joseph Chang, Zixuan Zhao, G Lavender Hackman, Eugenio Santelli, Colton M Sanders, Madhusudhanarao Katiki, Eleonora Dondossola, Brooke L Brauer, Michael A Diaz, Yuan Zhan, Sterling H Ramsey, Philip A Watson, Banumathi Sankaran, Claudia Paindelli, Vanessa Parietti, Antonios G Mikos, Alessia Lodi, Aditya Bagrodia, Andrew Elliott, Rana R Mckay, Ramachandran Murali, Stefano Tiziani, Arminja N Kettenbach, Nunzio Bottini
Faculty, Staff and Student Publications
Protein tyrosine phosphatases (PTPs) play major roles in cancer and are emerging as therapeutic targets. Recent reports suggest low-molecular weight PTP (LMPTP)-encoded by the ACP1 gene-is overexpressed in prostate tumors. We found ACP1 up-regulated in human prostate tumors and ACP1 expression inversely correlated with overall survival. Using CRISPR-Cas9-generated LMPTP knockout C4-2B and MyC-CaP cells, we identified LMPTP as a critical promoter of prostate cancer (PCa) growth and bone metastasis. Through metabolomics, we found that LMPTP promotes PCa cell glutathione synthesis by dephosphorylating glutathione synthetase on inhibitory Tyr270. PCa cells lacking LMPTP showed reduced glutathione, enhanced activation of eukaryotic initiation factor …
Prenatal Exposure To Maternal Disadvantage-Related Inflammatory Biomarkers: Associations With Neonatal White Matter Microstructure, Ashley F P Sanders, Brian Tirado, Nicole A Seider, Regina L Triplett, Rachel E Lean, Jeffrey J Neil, J Philip Miller, Rebecca Tillman, Tara A Smyser, Deanna M Barch, Joan L Luby, Cynthia E Rogers, Christopher D Smyser, Barbara B Warner, Et Al.
Prenatal Exposure To Maternal Disadvantage-Related Inflammatory Biomarkers: Associations With Neonatal White Matter Microstructure, Ashley F P Sanders, Brian Tirado, Nicole A Seider, Regina L Triplett, Rachel E Lean, Jeffrey J Neil, J Philip Miller, Rebecca Tillman, Tara A Smyser, Deanna M Barch, Joan L Luby, Cynthia E Rogers, Christopher D Smyser, Barbara B Warner, Et Al.
2020-Current year OA Pubs
Prenatal exposure to heightened maternal inflammation has been associated with adverse neurodevelopmental outcomes, including atypical brain maturation and psychiatric illness. In mothers experiencing socioeconomic disadvantage, immune activation can be a product of the chronic stress inherent to such environmental hardship. While growing preclinical and clinical evidence has shown links between altered neonatal brain development and increased inflammatory states in utero, the potential mechanism by which socioeconomic disadvantage differentially impacts neural-immune crosstalk remains unclear. In the current study, we investigated associations between socioeconomic disadvantage, gestational inflammation, and neonatal white matter microstructure in 320 mother-infant dyads over-sampled for poverty. We analyzed maternal …
Covid-19 Vaccine And Survival Of Diabetes Patient On Dialysis, Luis Guillermo De Jesús Iii Vega
Covid-19 Vaccine And Survival Of Diabetes Patient On Dialysis, Luis Guillermo De Jesús Iii Vega
Walden Dissertations and Doctoral Studies
No abstract provided.
African Americans’ Nutrition And Dietary Management Experiences To Mitigate Congestive Heart Failure, Chukwuemeke Joseph Onokwai
African Americans’ Nutrition And Dietary Management Experiences To Mitigate Congestive Heart Failure, Chukwuemeke Joseph Onokwai
Walden Dissertations and Doctoral Studies
No abstract provided.
The Role Of Educational Status And The Management Of Diabetes Among Mexican Migrants On The Northern Mexican Border, Suvipuli Mayarata Quinn
The Role Of Educational Status And The Management Of Diabetes Among Mexican Migrants On The Northern Mexican Border, Suvipuli Mayarata Quinn
Walden Dissertations and Doctoral Studies
No abstract provided.
Fostering Empathy In Communication Sciences And Disorders Through Interprofessional Simulation: Bridging The Gap Between Lecture And Practice, Cynthia A. Hovland, Carol Spears, Melissa Volk
Fostering Empathy In Communication Sciences And Disorders Through Interprofessional Simulation: Bridging The Gap Between Lecture And Practice, Cynthia A. Hovland, Carol Spears, Melissa Volk
Teaching and Learning in Communication Sciences & Disorders
This exploratory study sought to understand the experiences of CSD students participating in an interprofessional simulation focused on empathy development and how it could inform their future practice. This study used a non-random, purposive sample of 29 CSD students from one United States university who attended one of three Team STEPPS seminar training days that were offered during three separate semesters. Post-seminar surveys were completed, and conventional content analysis used to analyze data. Three primary themes, and corresponding subthemes emerged: (a) establish trust (build rapport; identify patient care goals; and encourage active participation; (b) facilitate collaborative plan of care (provide …
Faculty Senate Meeting Minutes February 2024, Faculty Senate
Faculty Senate Meeting Minutes February 2024, Faculty Senate
Faculty Senate Minutes
No abstract provided.
Development And Optimisation Of Convolutional Neural Networks (Cnns) To Predict The Nutrition And Sustainability Scores Of Foods From Crowd Sourced Images, Cormac Mcelhinney
Development And Optimisation Of Convolutional Neural Networks (Cnns) To Predict The Nutrition And Sustainability Scores Of Foods From Crowd Sourced Images, Cormac Mcelhinney
MSc in Data Analytics
This research explores the use of Convolutional Neural Networks (CNNs) for the automated classification and profiling of food products based on publicly sourced data. With so many food products available to consumers worldwide and by default, their labels, presents a challenging task for food business operators to conform to the complex regulations and for regulators to verify compliance with these requirements. With the increasing importance of data analytics in various domains, including food chains and agriculture, this study addresses the need for efficient and accurate methods for the classification and eco / nutritional profiling of foods in a timely manner.
Building Blocks For A Happy Life: Longitudinal Associations Between Early Life Income, Mentorship And Later Well-Being, Thomas Chan, Veronica Fruiht, Nicardo Mcinnis
Building Blocks For A Happy Life: Longitudinal Associations Between Early Life Income, Mentorship And Later Well-Being, Thomas Chan, Veronica Fruiht, Nicardo Mcinnis
Psychology | Faculty Scholarship
Longitudinal data from the Panel Study of Income Dynamics (PSID; N = 2996) were used to test hypotheses about the link between well‐being and financial and social developmental resources. Results suggest that higher average family income from birth to age 18, and personal and professional mentoring received between 17 and 30, were positively associated with indicators of positive well‐being and negatively related to negative indicators of well‐being. Interactions between early life family income and mentoring during emerging adulthood were not significant predictors of any of the well‐being outcomes. In all cases, the magnitudes of the coefficients became larger when simultaneously …
Diversity And Prevalence Of Zoonotic Infections At The Animal-Human Interface Of Primate Trafficking In Peru, A. Patricia Mendoza, Ana Muñoz-Maceda, Bruno M. Ghersi, Micaela De La Puente, Carlos Zariquiey, Nancy Cavero, Yovana Murillo, Miguel Sebastian, Yohani Ibañez, Patricia G. Parker, Alberto Perez, Marcela Uhart, Janine Robinson, Sarah H. Olson, Marieke H. Rosenbaum
Diversity And Prevalence Of Zoonotic Infections At The Animal-Human Interface Of Primate Trafficking In Peru, A. Patricia Mendoza, Ana Muñoz-Maceda, Bruno M. Ghersi, Micaela De La Puente, Carlos Zariquiey, Nancy Cavero, Yovana Murillo, Miguel Sebastian, Yohani Ibañez, Patricia G. Parker, Alberto Perez, Marcela Uhart, Janine Robinson, Sarah H. Olson, Marieke H. Rosenbaum
Biology Department Faculty Works
Wildlife trafficking creates favorable scenarios for intra- and inter-specific interactions that can lead to parasite spread and disease emergence. Among the fauna affected by this activity, primates are relevant due to their potential to acquire and share zoonoses - infections caused by parasites that can spread between humans and other animals. Though it is known that most primate parasites can affect multiple hosts and that many are zoonotic, comparative studies across different contexts for animal-human interactions are scarce. We conducted a multi-parasite screening targeting the detection of zoonotic infections in wild-caught monkeys in nine Peruvian cities across three contexts: captivity …
Truffle Cakes: A Family Tradition, Sam Haygood
Truffle Cakes: A Family Tradition, Sam Haygood
ENGL 1101 Showcase
What looks to be an ordinary chocolate cake sits unassumingly on a plate, but as the spoon pushes in for the first bite, it cracks through the outer crust of the cake and unexpectedly sinks into the center. Something special is about to come. As the spoon pulls out, the cake appears to be almost melting off the edge, and the prospect of waiting to eat it seems near impossible. This is the experience of my family’s best special occasion dessert, the truffle cake.
Community-Acquired Pneumonia, Children's Mercy Kansas City
Community-Acquired Pneumonia, Children's Mercy Kansas City
Clinical Pathways (Formally Known As Clinical Practice Guidelines)
No abstract provided.
Public Acceptance Of Using Artificial Intelligence-Assisted Weight Management Apps In High-Income Southeast Asian Adults With Overweight And Obesity: A Cross-Sectional Study, Han Shi Jocelyn Chew, Palakorn Achananuparp, Palakorn Achananuparp, Nicholas W. S. Chew, Yip Han Chin, Yujia Gao, Bok Yan Jimmy So, Asim Shabbir, Ee-Peng Lim, Kee Yuan Ngiam
Public Acceptance Of Using Artificial Intelligence-Assisted Weight Management Apps In High-Income Southeast Asian Adults With Overweight And Obesity: A Cross-Sectional Study, Han Shi Jocelyn Chew, Palakorn Achananuparp, Palakorn Achananuparp, Nicholas W. S. Chew, Yip Han Chin, Yujia Gao, Bok Yan Jimmy So, Asim Shabbir, Ee-Peng Lim, Kee Yuan Ngiam
Research Collection School Of Computing and Information Systems
Introduction: With in increase in interest to incorporate artificial intelligence (AI) into weight management programs, we aimed to examine user perceptions of AI-based mobile apps for weight management in adults with overweight and obesity. Methods: 280 participants were recruited between May and November 2022. Participants completed a questionnaire on sociodemographic profiles, Unified Theory of Acceptance and Use of Technology 2 (UTAUT2), and Self-Regulation of Eating Behavior Questionnaire. Structural equation modeling was performed using R. Model fit was tested using maximum-likelihood generalized unweighted least squares. Associations between influencing factors were analyzed using correlation and linear regression. Results: 271 participant responses were …
Nursing News & Views - February 2024, Joanne Miller Rn
Nursing News & Views - February 2024, Joanne Miller Rn
Nursing Newsletters
No abstract provided.
Firefighter Health: A Narrative Review Of Occupational Threats And Countermeasures, Drew E. Gonzalez, Sarah N. Lanham, Steven E. Martin, Richard E. Cleveland, Thad E. Wilson, Emily L. Langford, Mark G. Abel
Firefighter Health: A Narrative Review Of Occupational Threats And Countermeasures, Drew E. Gonzalez, Sarah N. Lanham, Steven E. Martin, Richard E. Cleveland, Thad E. Wilson, Emily L. Langford, Mark G. Abel
UK CARES Faculty Publications
Structural firefighters are responsible for protecting properties and saving lives during emergency operations. Despite efforts to prepare firefighters for these hazardous occupational demands, the unfortunate reality is that the incidence of health morbidities is increasing within the fire service. Specifically, cardiovascular disease, cancer, and mental health disorders are among the most documented morbidities in firefighters. Pubmed and Google Scholar search engines were used to identify peer-reviewed English language manuscripts that evaluated firefighters’ occupational health threats, allostatic factors associated with their occurrence, and evidence-based strategies to mitigate their impact. This narrative review provides fire departments, practitioners, and researchers with evidence-based practices …
Higher Glycemic Index And Glycemic Load Diet Is Associated With Slower Disease Progression In Amyotrophic Lateral Sclerosis, Ikjae Lee, Hiroshi Mitsumoto, Seonjoo Lee, Edward J. Kasarskis, Michael Rosenbaum, Pam Factor-Litvak, Jeri W. Nieves
Higher Glycemic Index And Glycemic Load Diet Is Associated With Slower Disease Progression In Amyotrophic Lateral Sclerosis, Ikjae Lee, Hiroshi Mitsumoto, Seonjoo Lee, Edward J. Kasarskis, Michael Rosenbaum, Pam Factor-Litvak, Jeri W. Nieves
Neurology Faculty Publications
Objective: High-caloric diets may slow the progression of amyotrophic lateral sclerosis; however, key macronutrients have not been identified. We examined whether dietary macronutrients are associated with the rate of progression and length of survival among the prospective cohort study participants.
Methods: Participants with a confirmed diagnosis of sporadic amyotrophic lateral sclerosis enrolled in the Multicenter Cohort Study of Oxidative Stress were included (n = 304). We evaluated baseline macronutrient intake assessed by food frequency questionnaire in relation to change in revised amyotrophic lateral sclerosis functional rating scale total- score, and tracheostomy-free survival using linear regression and Cox proportional hazard models. …
Place-Based Multimodal Narratives With Storymap Js, Laurel Phillips, Johnny Allred
Place-Based Multimodal Narratives With Storymap Js, Laurel Phillips, Johnny Allred
The Utah English Journal
At the beginning of a recent cross-country road trip, Johnny pulled open a map app on his phone and entered his final destination—Fort Worth, Texas—into the search bar, along with three other stops: the Maverik in Moab (he had to load up on Dr. Pepper); a hotel in Santa Rosa, New Mexico; and “Cadillac Ranch” in Amarillo (Google it). For the next 1,200 miles, the digital map guided him and his family along the path, setting the stage for experiences and stories that the family will tell and retell for years to come.
That example—the use of maps to guide …
Effect Of Different Molecular Weight Hyaluronic Acids On Skim Milk Functional Properties, Rutvi Joshi, Suresh G. Sutariya, Prafulla Salunke
Effect Of Different Molecular Weight Hyaluronic Acids On Skim Milk Functional Properties, Rutvi Joshi, Suresh G. Sutariya, Prafulla Salunke
Dairy Science and Food Science Faculty Publications: 2022 to Present
Hyaluronic acid (HA), a naturally occurring polysaccharide with recognized health benefits, has gained approval for use in the food industry as a food additive, ingredient, and health supplement in numerous countries. HA can increase viscosity in solutions and is available commercially in various molecular weights (MW) depending on end applications. Nevertheless, no research has explored the impact of different MW HAs on functionality, rheological properties, and texture-building benefits in the dairy product matrix wherein they are incorporated. Therefore, the objective of this study was to evaluate how varying MWs of HA—specifically 8 kDa, 320 kDa, 980 kDa, and 2550 kDa …
Preferential Binding Of Polyphenols In Blackcurrant Extracts With Milk Proteins And The Effects On The Bioaccessibility And Antioxidant Activity Of Polyphenols, Ting Mao, Fnu Akshit, Iresha Matiwalage, Subha Sasidharan, Caren Meyn Alvarez, Philip Wescombe, Maneesha S. Mohan
Preferential Binding Of Polyphenols In Blackcurrant Extracts With Milk Proteins And The Effects On The Bioaccessibility And Antioxidant Activity Of Polyphenols, Ting Mao, Fnu Akshit, Iresha Matiwalage, Subha Sasidharan, Caren Meyn Alvarez, Philip Wescombe, Maneesha S. Mohan
Dairy Science and Food Science Faculty Publications: 2022 to Present
Milk proteins are well-known delivery agents; however, there is no clear understanding of the competitive interactions of milk proteins with polyphenols in mixed complex systems. Here, we investigate the preferential competitive interactions of different polyphenols present in blackcurrant extract with milk proteins by quantifying the protein-bound polyphenols and comparing the factors affecting these interactions. In addition, bioaccessibility and antioxidant activity were studied after in vitro gastric digestion. Our results indicated that polyphenols from blackcurrant extracts were preferentially bound to caseins more than whey proteins, with noncovalent interactions causing secondary structural changes in the protein. The hydrophobicity and the charge of …