Digital Commons Network^™

The Role And Mechanism Of Cinnamaldehyde In Cancer, Jiahua Peng, Xin Song, Wenbin Yu, Yuhan Pan, Yufei Zhang, Hui Jian, Bin He

Journal of Food and Drug Analysis

As cancer continues to rise globally, there is growing interest in discovering novel methods for prevention and treatment. Due to the limitations of traditional cancer therapies, there has been a growing emphasis on investigating herbal remedies and exploring their potential synergistic effects when combined with chemotherapy drugs. Cinnamaldehyde, derived from cinnamon, has gained significant attention for its potential role in cancer prevention and treatment. Extensive research has demonstrated that cinnamaldehyde exhibits promising anticancer properties by modulating various cellular processes involved in tumor growth and progression. However, challenges and unanswered questions remain regarding the precise mechanisms for its effective use as …

Trends And Current Food Safety Regulations And Policies For Functional Foods And Beverages Containing Botanicals, Jarunee Intrasook, Takuji W. Tsusaka, Anil Kumar Anal

Journal of Food and Drug Analysis

Globally, the demand for functional foods and beverages has significantly increased due to socioeconomic changes, particularly in health consciousness to enhance their functionality. Functional ingredients derived from botanicals are widely used because of their phytochemical properties with health benefits. This study aims to (1) review the capabilities and challenges of botanical addition in functional foods, (2) review current policies and regulations for functional foods containing botanicals in the European Union (EU), Canada, Japan, the Republic of Korea, and Thailand, and (3) provide recommendations on effective food safety control measures for better consumer trust and trade facilitation. This critical review was …

Trends In Selected Heart Diseases Among Below Poverty Line Population From Karnataka State, South India, Devajana Chinnappa Nanjunda, Rajesh H. Acharya, Amit Kumar Mishra, Subramani Jyothi Lakshmi, Prasanna K Santhekadur

International Journal of Health and Allied Sciences

Objective: The study aims to reveal the most common heart diseases found among the below-the-poverty-line (BPL) population in Karnataka State (South India) using SAST data. Method: This study has been done using the data found in the Suvarna Arogya Suraksha Trust on below-the-poverty line (BPL) categories Results and

Discussion: It is found that the coronary artery disease, myocardial infarction, Bradycardia, pericarditis. Arrhythmia was found common among BPL section

Conclusion: Poverty, material deprivation, social exclusion, health disparity, and poor social cohesion throughout the life course among the BPL community are the key reasons for poor cardiac care and related outcomes.

Identifying The Lead Molecule From Carica Papaya Using Computer-Aided Drug Design Technique Against Streptococcus Pneumoniae, Prajwal Bhanu, Sushma Pradeep, Pruthvish Reddy, Prashanth Vishwanath, Sumanth R M, Girish M S, Bhargav Shreevatsa, Anisha S. Jain, Chandan Dharmashekara, Shiva Prasad Kollur, Sai Chakith Mr, Ashwini P, Chandan Shivamallu, Chandrashekar Srinivasa

International Journal of Health and Allied Sciences

Streptococcus pneumoniae, a gram-positive cocci bacterium found in the oral cavity and nasopharynx of humans causes acute respiratory infections and pneumonia progression. This study aims to identify highly susceptible, antimicrobial, therapeutic phytochemicals from the leaf extract of the medicinal Carica papaya plant which acts as antibiotic by inhibiting the mechanism of action of Streptococcus species. Using an in silico molecular docking approach, the 3D ligand structures of the screened phytoconstituents of Carica papaya are made to dock with the active pocket of targeted proteins i.e. Cytidine deaminase, 5' methylthionadenosine/S-Adenosylhomocysteine nucleosidase and phosphomevalonate Kinase in Complex with Phosphomevalonate and AMPPNP …

Empowerher: A Pilot Study To Increase Physical Activity And Strength Through Powerbuilding, Aspen E. Streetman, Murry T. Streetman, Halle N. Brin, Emily L. Mailey, Katie M. Heinrich

International Journal of Exercise Science

International Journal of Exercise Science 17(8): 750-767, 2024. Engaging in empowering exercise develops movement competency (MC) and strength and supports physical health, mental well-being, and quality of life. Powerbuilding combines powerlifting and bodybuilding to increase physical activity (PA), MC, and strength. To our knowledge, powerbuilding has not been explored as an exercise intervention. This pilot study investigated the impact of an eight-week powerbuilding intervention on women’s PA, MC, strength, and empowerment. Eighteen women aged 25.1±9.8 with no powerbuilding experience participated in the intervention, meeting three times weekly for one hour. PA and MC were assessed pre- and post-intervention. Three-repetition maximum …

The 2024 International Journal Of Exercise Science Position Stand On Inclusion, James W. Navalta, Dustin W. Davis, Jafra Thomas, Matthew J. Garver, Shannon Siegel, Joel D. Reece, Jill M. Maples

International Journal of Exercise Science

International Journal of Exercise Science 17(8): 730-749, 2024. The International Journal of Exercise Science (IJES) Working Group for Opportunity, Representation, and Diverse Perspectives was tasked with developing a position stand to provide guidance in critical areas of inclusion. We present to authors, reviewers, and all readership IJES ideals to utilize in practice. Key points are presented, followed by a deeper look with greater explanation into the areas of inclusive language, diversity and inclusion in research, and accessibility. The same approach is presented for the areas of age, disability status, gender identity and sexual orientation, race, and ethnicity with attention to …

The Origin And Lifespan Of Food Assistance Programs During The Great Depression, Vincet Gottfried Wisehoon

Chronos

No abstract provided.

Neonatal Intensive Care Nurses' Perceptions Of Nurse Leader Behaviors And Their Impact On The Workplace Environment, Meggan R. Mcculley

Dissertations

Nursing leadership is a crucial component in today's healthcare organizations as nurses make up the largest profession in healthcare overall. Nurse leaders have the ability to affect the environment of the nurses' workplace in both positive and negative ways, thus impacting their Quality of Nurse Work Life (QNWL). QNWL is an indicator of nurse satisfaction within their workplace, and the ability of the nurse to make meaningful contributions to their home units and the organization. The purpose of this qualitative, interpretative phenomenological analysis (IPA) study was to describe what it meant to experience nursing leadership from the perspective of Level …

Neuroimaging Evaluation Of The Long Term Impact Of A Novel Paired Meditation Practice On Brain Function, Andrew B. Newberg, Nancy Wintering, Chloe Hriso, Faezeh Vedaei, Sara Gottfried, Reneita Ross

Marcus Institute of Integrative Health Faculty Papers

BACKGROUND: A growing number of advanced neuroimaging studies have compared brain structure and function in long term meditators to non-meditators. The goal is to determine if there may be long term effects on the brain from practicing meditation. In this paper, we present new data on the long term effects of a novel meditation practice in which the focus is on clitoral stimulation. The findings from such a study have implications for potential therapeutic uses with regard to various neurological or psychiatric conditions.

METHODS: We evaluated the cerebral glucose metabolism in 40 subjects with an extended history (>1 year …

The Effects Of Intermittent Fasting On The Size And Number Of Subcutaneus Adipocytes In Obese Mouse Models, Veny Larasati, Riana Sari Puspita Rasyid, Soilia Fertilita, Tri Suciati, Muhammad Farhan

Folia Medica Indonesiana

Highlights: 1. This study helps bridge the gap between systemic effects and tissue-level changes, providing a deeper understanding of how histological analysis can be used to explore the effects of intermittent fasting on adipocytes and body weight regulation. 2. This study contributes to obesity management through lifestyle modification, specifically intermittent fasting, by focusing on histological changes in adipose tissue. Abstract The accumulation of adipose tissue can have deleterious effects and lead to obesity. Intermittent fasting (IF), an approach that involves time-restricted eating, has gained popularity as an obesity treatment option because it enhances insulin sensitivity and promotes beneficial changes in …

Estrous Cycle And Uterine Weight Of Ovariectomized Menopause Female Rat Models After Treatment With Leucaena Leucocephala (Lam.) De Wit Leaf Extract, Ngurah Intan Wiratmini, Anak Agung Sagung Alit Sukmaningsih, Iriani Setyawati

Folia Medica Indonesiana

Highlights: 1. This study found that Leucaena leucocephala leaf ethanol extract has the ability to stimulate the growth of vaginal epithelial cells in ovariectomised rats. 2. Leucaena leucocephala leaf extract can be developed as a safe and cost-effective natural alternative for hormone replacement therapy in premenopausal women and livestock. Highlights: 1. This study found that Leucaena leucocephala leaf ethanol extract has the ability to stimulate the growth of vaginal epithelial cells in ovariectomised rats. 2. Leucaena leucocephala leaf extract can be developed as a safe and cost-effective natural alternative for hormone replacement therapy in premenopausal women and livestock. Abstract Hormone …

Attenuation Of Cadmium Toxicity By Methanol Extracts Of Rauvolfia Vomitoria And Aframomum Melegueta Leaves, Temidayo Adeniyi, Moronkeji Akinpelu, Omokehinde Akinlami, Molade James Kolawole, Jesufemi Oloye, Imoleayo Akogun

Folia Medica Indonesiana

Highlights: 1. This study provides insight into the detrimental effect of cadmium exposure on mammalian cells using a murine model. 2. The co-administration of Rauvolfia vomitoria and Aframomum melegueta leaf extracts is more effective in ameliorating cadmium-induced toxicity than a single administration of each plant extract. 3. The co-administration of Rauvolfia vomitoria and Aframomum melegueta plant extracts can upregulate the expression of IL-10 and reverse the derangements in the TNF-α, IL-6, SOD, and GPX levels. Abstract Cadmium has long been known to be an environmental pollutant that can harm human health, with toxicity majorly affecting the kidneys and liver. This …

Differences In Aerobic Capacity And Running Speed Across Various Somatotype Structures And Body Fat Compositions Among Professional Football Athletes In Indonesia, Dhoni Akbar Ghozali, Muhammad Syauqi Ridhallah, Syania Shabrina, Ahmad Isnaini Shidqi Nurhani, Yunia Hastami, Dwi Rahayu, Lukman Aryoseto, Selfi Handayani, Siti Munawaroh, Nanang Wiyono, Agus Sugeng Riyanto, Enrico Ananda Budiono, Annisa Aghnia Rahma, Muhana Fawwazy Ilyas

Folia Medica Indonesiana

Highlights: 1. This study emphasizes the significance of understanding professional football players' various somatotype structures and body fat compositions as an important contribution to the area of sports science. This study lays the groundwork for future research to better understand the intricate interactions between somatotype structures, body composition, and athletic performance. 2. Since a one-size-fits-all approach may not be successful, this study advocates for tailored evaluations of training regimens to cater to athletes' unique requirements and skills, which may lead to higher overall performance. Abstract This study investigated the effects of somatotype structures and body fat composition on professional football …

Concepts In Animal Parasitology, Scott L. Gardner, Sue Ann Gardner

Zea E-Books Collection

Note that this version of the textbook has been superceded by the one updated in 2026, available at the UNL Pressbooks site.

The hard copy version that is for sale at lulu.com is the old version.

"This is a textbook covering concepts in animal parasitology. It is meant to be used by students, teachers, professors, researchers, and members of the public who are interested in learning about animal parasite biology, systematics, taxonomy, zoogeography, and ecology. The primary intended audience is upper-level undergraduate or graduate university students who have knowledge of basic biology and, particularly, basic animal biology. (863 pages, …

Reducing Heart Failure 30-Day Hospital Readmissino Rates Through A Post Discharge Educational Program, Yadira Pagano

DNP and Student Works

Congestive heart failure is a complex and debilitating condition affecting millions of people nationwide resulting in frequent admissions to the hospital and decreasing patient's quality of life and costing thousands of dollars not only to patients by to the healthcare system. The proposed quality improvement project is aimed at reducing Heart Failure 30-day hospital readmission rates by implementing a post-discharge educational program. The program consists of weekly contact with heart failure patients recently discharged from the hospital to reinforce discharge education topics.

Climate Regulation And Co-Benefits: The Reality Of Co-Benefits In Climate Policy And The Reality We Face Without Them, Riley Jacobs

San Diego Journal of Climate & Energy Law

The United States has long required administrative agencies to conduct Cost-Benefit Analyses (“CBA”) in their rulemaking. By conducting CBA, agencies “show their work” to Congress, courts, and constituencies as to why the agency wishes to regulate a certain way and what it would cost to do so.

This Article will focus on co-benefits, an increasingly divisive component of CBA. Co-benefits, or benefits occurring secondary to the targeted purpose of statutory authority, assist agencies like the Environmental Protection Agency (“EPA”) in painting a holistic picture of everything the public has to gain from a rule’s passage. In recognizing that value, the …

Folate As A Potential Treatment For Lethal Ventricular Arrhythmias In Tango2-Deficiency Disorder, Weiyi Xu, Yingqiong Cao, Sara B Stephens, Maria Jose Arredondo, Yifan Chen, William Perez, Liang Sun, Andy C Yu, Jean J Kim, Seema R Lalani, Na Li, Frank T Horrigan, Francisco Altamirano, Xander Ht Wehrens, Christina Y Miyake, Lilei Zhang

Faculty, Staff and Students Publications

TANGO2-deficiency disorder (TDD) is an autosomal-recessive genetic disease caused by biallelic loss-of-function variants in the TANGO2 gene. TDD-associated cardiac arrhythmias are recalcitrant to standard antiarrhythmic medications and constitute the leading cause of death. Disease modeling for TDD has been primarily carried out using human dermal fibroblast and, more recently, in Drosophila by multiple research groups. No human cardiomyocyte system has been reported, which greatly hinders the investigation and understanding of TDD-associated arrhythmias. Here, we established potentially novel patient-derived induced pluripotent stem cell differentiated cardiomyocyte (iPSC-CM) models that recapitulate key electrophysiological abnormalities in TDD. These electrophysiological abnormalities were rescued in iPSC-CMs …

Increasing Pre-Service Teachers' Awareness Of Children Experiencing Homelessness, Rachael Waller, Melissa Sullivan-Walker

The Reading Professor

As homelessness becomes a growing issue in the United States, children experiencing homelessness can be educationally at risk. However, teachers can make a significant difference for these children. In this study, we sought to increase empathy and understanding for children experiencing homelessness for the pre-service teachers whom we teach. Using the windows, mirrors and sliding glass doors framework (Bishop, 1990), we implemented an activity in which pre-service teachers read and discussed children's books portraying different types of homelessness. This paper will articulate how students made connections with the texts and deepened their understanding and empathy about children experiencing homelessness.

Slime Molds (Myxomycetes) Causing A “Disease” In Crop Plants And Cultivated Mushrooms, Zhaojuan Zhang, Chao Zhi, Yu Li, Steven L. Stephenson, Pu Liu

Biological Sciences Faculty Publications and Presentations

Myxomycetes (plasmodial slime molds) are eukaryotic protist predators that are associated with wood, leaf litter, and soil in forests, where they feed on bacteria, protozoans, and (to a more limited extent) fungi. The health of crop plants is essential because they represent a primary food source for humans. However, when myxomycetes produce numerous fruiting bodies on the stems and leaves of crop plants, which is herein referred to as a myxomycete colonization, this has the potential of interfering with plant photosynthesis, transpiration and respiration by blocking out light and covering stomata. Myxomycetes are not pathogens, but their occurrence on plants …

Fiscal Incentives For Green Growth: A Mixed-Methods Study Of The State Of Agroforestry And Tree Cover In India, Spriha Pandey

Environmental Studies Senior Theses

Agroforestry is a crucial strategy for diversifying farmer livelihoods and achieving India's climate goals, but its adoption has been hindered by institutional and fiscal obstacles. This mixed-methods study investigates the impact of national government schemes on tree cover increase and expert perceptions of incentives and barriers to agroforestry adoption. Our analysis of national schemes from 2013-2017 reveals that effective fiscal mechanisms and policy cohesion are critical drivers of agroforestry growth. Specifically, we find that increased funding for the Rural Employment Guarantee Scheme (MGNREGS) is associated with significant increases in tree cover area while funding for the Horticultural Scheme (NHM) is …

The Impact Of Maine’S Municipal Shellfish Management On Clam Harvester Motivation To Participate In Resource Conservation, Rachel Lohr Freer

Environmental Studies Senior Theses

This study investigates how the resource management strategies implemented by Maine’s different Municipal Shellfish Conservation Committees influences the motivation held by shellfish harvesters’ to participate in resource conservation activities. As soft shell clam landings are declining across Maine due to increasing predation and climate-related stress, there seems to be a disconnect in harvesters’ willingness to support the conservation activities that Shellfish Conservation Committees make available to them. In efforts to improve participation, town leadership in select regions have started to mandate the completion of annual conservation hours requirements. The diversity of policy approaches enacted by towns provides the unique opportunity …

Land-Use Governance And Indigenous Engagement In Arctic Alaska And Norway: Successes, Current Gaps, And Paths Forward, Ningning Sun

Environmental Studies Senior Theses

This study aims to analyze the land use governance structures and the role of Indigenous engagement in Alaska and Norway using a comparative approach, with special focus on successful practices, current gaps, and paths forward to achieve equitable governance. Extractive land uses, such as oil and gas extraction and the construction of wind farms, have mixed impacts on Indigenous communities and lead to social and legal issues such as land use conflict and environmental injustice. Previous research has studied land use governance in Arctic countries with regard to Indigenous Peoples, yet there is a lack of literature that spans Alaska …

Native American And First-Nations Canadian And Physical Pfas Accumulations: A Literature Review, Laurel Liebeseller

University Honors Theses

Native communities' exposure to anthropogenic Per- and Polyfluoroalkyl Substances (PFAS: "Forever Chemicals") are not demographically or geographically evenly distributed. Those who live near or on contaminated land or water are the most likely to accumulate dangerous amounts of PFAS that may have serious health consequences (Tribal PFAS Working Group 2021). Areas that tend to be most contaminated include landfills, airports, and military bases. Often Black, Indigenous People of Color (BIPOC) and low-income communities are placed near these "sacrificial zones" due to historic and current policies that segregate and marginalize people and families to polluted lands creating great environmental injustices (Dixie). …

Feasibility Of Achieving Nutritional Adequacy In Critically Ill Children With Critical Neurological Illnesses (Cnis)?-A Quaternary Hospital Experience, Marwa Mansour, Nicole Knebusch, Jennifer Daughtry, Thomas P Fogarty, Fong Wilson Lam, Renan A Orellana, Yi-Chen Lai, Jennifer Erklauer, Jorge A Coss-Bu

Faculty, Staff and Students Publications

The literature on the nutritional needs and outcomes of critically ill children is scarce, especially on those with critical neurological illnesses (CNIs). Current evidence shows a lower mortality in patients who achieve two-thirds of their nutritional needs during the first week of pediatric intensive care unit (PICU) admission. We hypothesized that achieving 60% of the recommended dietary intake during the first week of a PICU stay is not feasible in patients with CNI. We designed an observational retrospective cohort study where we included all index admissions to the PICU in our institution of children (1 month to 18 years) with …

Evaluation Of 14 Pfas For Permeability And Organic Anion Transporter Interactions: Implications For Renal Clearance In Humans, Sangwoo Ryu, Emi Yamaguchi, Seyed Mohamad Sadegh Modaresi, Juliana Agudelo, Chester Costales, Mark A. West, Fabian Fischer, Angela L. Slitt

Biomedical and Pharmaceutical Sciences Faculty Publications

Per- and polyfluoroalkyl substances (PFAS) encompass a diverse group of synthetic fluorinated chemicals known to elicit adverse health effects in animals and humans. However, only a few studies investigated the mechanisms underlying clearance of PFAS. Herein, the relevance of human renal transporters and permeability to clearance and bioaccumulation for 14 PFAS containing three to eleven perfluorinated carbon atoms (η_pfc = 3–11) and several functional head-groups was investigated. Apparent permeabilities and interactions with human transporters were measured using in vitro cell-based assays, including the MDCK-LE cell line, and HEK293 stable transfected cell lines expressing organic anion transporter (OAT) 1–4 …

Salmon Mislabeling Rates Uncovered In Restaurants And Grocery Stores In Seattle, Jewel L. Garcia, Jewel L. Garcia

Honors Projects

Salmon has been a cultural icon in Seattle, Washington for many generations because it has and continues to sustain the people who reside on this land. Seafood fraud, in which a seafood’s genetic identity does not match its vendor-claimed identity, is not a new phenomenon, and many studies have been conducted internationally to explore the extent of this issue. With human and environmental health concerns on the line, a salmon fraud (mislabeling) study must be conducted in a state where immensely high salmon sales and serious recreational efforts occur to assess Seattle’s marketplace honesty. By genetically barcoding the highly conserved …

Black Football Student-Athletes’ Perceived Barriers To Seeking Mental Health Services, Todd A. Wilkerson, Sarah Stokowski, Alison Fridley, Stephen W. Dittmore, Charles A. Bell

Journal of Issues in Intercollegiate Athletics

Black male student-athletes have endured frequent stereotyping on college campuses (Hawkins, 2010). Additionally, Black student-athletes have experienced educational, campus, and athletic stressors (Miller & Hoffman, 2009). Many student-athletes do not seek mental health services because of their status on campus (Watson, 2005). The general population has experienced common barriers in seeking mental health services including low socio-economic status (Hurd, Stoddard, & Zimmerman, 2013) and negative stigmas related to metal illness (Wang et al., 2005). While it is reasonable to assume similar challenges exist for Black student-athletes, it must be investigated empirically. As such, the purpose of this study was to …

Connected At The Hip: Exploring Quality Dimensions In First-Year Seminars For Student-Athletes, Nikola Grafnetterova, Chelsie L. Hawkinson, Rachel L. Rodriguez

Journal of Issues in Intercollegiate Athletics

First-year seminars have been identified as a high-impact practice resulting in heightened academic performance, retention, and skill attainment (Kuh, 2008). Many higher education institutions offer exclusive sections of this transition course to first-year student-athletes, but a lack of research exists about their curriculum and learning outcomes. As such, this study sought to examine the design of first-year seminars for student-athletes as it relates to their quality implementation. The review of syllabi and institutional websites revealed that first-year seminars address a wide range of student-athlete needs, and for the most part, meet the expectations of HIP quality dimensions. Yet, this study …

Understanding Student-Athlete Reintegration: Using Social Work Strengths, Charlotte E. Dean, Jerry F. Reynolds Ii

Journal of Issues in Intercollegiate Athletics

The reintegration process that follows a student athlete’s unplanned retirement from sport is common among student-athletes. Upon reintegration there are factors that influence an athlete’s ability to remain on campus. These include positive social supports, personal skills, coping skills, and goal setting. There are also more negative reintegration factors such as isolation and role engulfment, limited social supports, lack of preparation, limited personal living skills and emotional regulation, and negative stereotypes from the general collegiate population. A case study helps illustrate the difficulties that a student-athlete may encounter during the reintegration process and how professionals can assist in a more …

Is There A Need For Social Workers In Intercollegiate Athletics? A Conceptual Study, Raymond Waller, Christina L. L. Martin, Samantha Morgan

Journal of Issues in Intercollegiate Athletics

Research regarding eating disorders among intercollegiate female athletes is well-documented. Since eating disorders have been categorized as potentially serious mental illnesses by the American Psychiatric Association (APA, 2013), professionals need to be knowledgeable and involved in the overall care of college athletes. However, those closest to the athlete such as athletic trainers and coaches often lack the knowledge to detect symptoms and/or ability to assist those afflicted with eating disorders. To make a difference, a health care professional, such as a clinically trained social worker, should be considered to assist with the well-being of athletes. This conceptual study explores the …