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Medicinal Plants As Indicators Of Grassland Biodiversity, G Nagy, I Vinczeffy, K Peto Jun 2024

Medicinal Plants As Indicators Of Grassland Biodiversity, G Nagy, I Vinczeffy, K Peto

IGC Proceedings (1977-2023)

A study has been made to identify the medicinal plants on the existing Hungarian grasslands. Sixty-three plants have been found to possess medicinal effects. Twenty-six, 15 and 22 species are for internal, internal or external and external use, respectively. This result reflects the low management intensity of grasslands in the country, as well as the species richness of semi-natural grasslands. It is suggested that the number of medical plants on the grassland, - in general - can also be used as an indicator of grassland biodiversity.


Mineral Contents Of White Clover Grass And Nitrogen Fertilized Grass Pastures For Lambs, R Sormunen-Cristian, P Nykänen-Kurki, J Peltola Jun 2024

Mineral Contents Of White Clover Grass And Nitrogen Fertilized Grass Pastures For Lambs, R Sormunen-Cristian, P Nykänen-Kurki, J Peltola

IGC Proceedings (1977-2023)

The mineral contents (Ca, P, Mg, K, Na, Fe, Cu, Zn, and Mn) of white clover grass without nitrogen and grass-only pastures with annual nitrogen rates of 0, 120 and 250 kg ha-1 were studied in 1994 and 1995. The pastures were grazed twice per season by growing lambs. The white clover contents averaged 25% and 42%, respectively. The Ca and Mg contents and the Ca/P ratio were higher, and the K/(Ca+Mg) equivalent ratio lower in white clover grass than in grass-only swards. The P content of white clover grass was similar to that of grass, and the K content …


Collection And Evaluation Of The Section Platycarpe From The Peoples Republic Of China, T A. Cambell, G Bao, Z L. Xia Jun 2024

Collection And Evaluation Of The Section Platycarpe From The Peoples Republic Of China, T A. Cambell, G Bao, Z L. Xia

IGC Proceedings (1977-2023)

The Peoples Republic of China is the center of origin of several species of the section Platycarpae, which could contain genes for drought and cold tolerance that would be of significant benefit to cultivated alfalfa (Medicago sativa L.) Of particular interest are Medicago archiducis-nicolai Sirjaev, M. edgeworthii Sirjaev, and M. ruthenica (L.) Ledebour. Of 105 M. ruthenica accessions collected from 15 diverse environments in Inner Mongolia, 50 were evaluated in the field at Beltsville MD (USA) in 1993 and 1994 on an acid soil (pH 6.4) deficient in boron and potassium. Significant variation was noted for stand retention, reaction to …


Assessing The Impact Of Dietary Addition Of Lignin On Growth Performance, Nitrogen Balance And Faecal Microorganisms In Grain-Fed Veal Calves, L E. Phillip, E S. Idziak Jun 2024

Assessing The Impact Of Dietary Addition Of Lignin On Growth Performance, Nitrogen Balance And Faecal Microorganisms In Grain-Fed Veal Calves, L E. Phillip, E S. Idziak

IGC Proceedings (1977-2023)

A study was conducted with ALCELLR - lignin (A-lignin) to evaluate its impact on performance of grain- fed veal calves. Thirty two male calves (avg. initial wt, 190 kg) were fed for 13 weeks grain corn and a protein supplement with added A-lignin to supply 0, 1.25%, 2.5% or 5.0% of diet. Eight other calves were used to study nitrogen balance, and grab samples of faeces were analyzed for anaerobic, aerobic and coliform bacteria. A-lignin at 1.25% of diet increased (p<.01) weight gain by 12%. Addition of A-lignin also decreased (p< 0.01) organic matter digestion, increased (p<.01) faecal N excretion but did not significantly alter N balance. A-lignin reduced (p< 0.01) faecal ammonia concentration but increased (p <.01) DM content of grab samples of faeces; there were no significant effects on populations of faecal microorganisms. The study revealed a beneficial effect of A-lignin on calf growth but the reason for the response was not uncovered.


Seed Proteinase Inhibitors From Annual Medics Active Against Insect Pests, M Odoardi, A Tava, F Ceciliani Jun 2024

Seed Proteinase Inhibitors From Annual Medics Active Against Insect Pests, M Odoardi, A Tava, F Ceciliani

IGC Proceedings (1977-2023)

Several different species of annual medics have been tested for the occurrence and concentration of trypsin inhibitors in the seed. Trypsin Inhibitory Activity (TIA) has been in fact related to the level of resistance to biotic and abiotic stresses. Wide variation was found for TIA among species, with the highest values shown by the snail medic (Medicago scutellata). After a simple and rapid procedure of chromatographic purification, the Trypsin Inhibitor (TI) from snail medic has been tested towards the trypsin-like proteinases extracted from larvae of different phytophagous insects, showing high levels of Inhibitory Activity. The complete amino acid …


The Effect On Intake Palatability And Digestibility Of Phenolic Compounds In Tagasaste (Chamaecytisus Proliferus), N J. Edwards, J C. Mailey, D M. Mcneill, J B. Lowry, C S. Mcsweeney, D A. Henry, C M. Oldham Jun 2024

The Effect On Intake Palatability And Digestibility Of Phenolic Compounds In Tagasaste (Chamaecytisus Proliferus), N J. Edwards, J C. Mailey, D M. Mcneill, J B. Lowry, C S. Mcsweeney, D A. Henry, C M. Oldham

IGC Proceedings (1977-2023)

The major secondary metabolites currently identified in tagasaste (Chamaecytisus proliferus) belong to the phenolic group of compounds. The principal phenolic compounds are the flavones, apigenin and luteolin, but low concentrations of condensed tannins, the isoflavonoid daidzein and the alkaloid sparteine have also been detected in some samples. No flavonols have been detected. There is a strong relationship between the concentration of phenolic compounds in tagasaste and its palatability. Furthermore, digestibility of tagasaste is relatively high throughout the year, thereby implicating intake as the major factor influencing the seasonality of liveweight performance of livestock grazing tagasaste. Despite confirmation of …


Feeding Strategies To Optimize Reproductive Performance Of Cattle Grazing High Protein Pastures In Uruguay, H R. Tosi, K M. Wittenberg Jun 2024

Feeding Strategies To Optimize Reproductive Performance Of Cattle Grazing High Protein Pastures In Uruguay, H R. Tosi, K M. Wittenberg

IGC Proceedings (1977-2023)

Alternative feeding strategies were investigated for Holstein heifers grazing a vegetative red, Trifolium pratense L., and white clover, Trifolium repens L., pasture. A total of 474 grazing heifers were supplemented varying amounts of corn silage, Zea mays, during the breeding season in an effort to improve reproductive performance. Animal response to supplementation, whether on spring or winter pasture, was similar. Corn silage supplemented at 18.8 or 28.8% DM basis of total diet, for winter and spring pastures, respectively, resulted in animal weight gains similar to that of heifers receiving legume pasture only. Serum urea nitrogen and reproductive performance for heifers …


Strategies For Improving Efficiency Of Beef Cattle In Tall Fescue Pasture Systems, J C. Waller, H A. Fribourg Jun 2024

Strategies For Improving Efficiency Of Beef Cattle In Tall Fescue Pasture Systems, J C. Waller, H A. Fribourg

IGC Proceedings (1977-2023)

A beef (Bos taurusL.) cattle producer must allocate land and forage resources to meet nutrient needs of the entire herd. Using 20 yr of calving and grazing data, templates of herd composition, associated Total Digestible Nutrients (TDN) requirements over the whole year, and forage TDN production were developed for a typical herd and land area. The monthly energy needed by the entire herd was relatively constant. Forage productivity varied monthly, indicating the need to plan for efficiently using surplus TDN from some seasons to meet needs at other times. This approach could be expanded to include more definitive …


Use Of Willows (Salix Spp) As Drought Fodder For Sheep, S K. Oppong, P D. Kemp, G B. Douglas, B T. Bulloch Jun 2024

Use Of Willows (Salix Spp) As Drought Fodder For Sheep, S K. Oppong, P D. Kemp, G B. Douglas, B T. Bulloch

IGC Proceedings (1977-2023)

The effects of cutting height and harvesting times on the forage yield, yield components and quality of Tangoio hybrid willow and Kinuyanagi willow were examined, to evaluate these willows as drought fodder for sheep. Tangoio (3.8 tDM/ha) outyielded Kinuyanagi (3 tDM/ha) in edible forage production and provided reasonable quality fodder (nitrogen content of 2.0 % and digestibility of 65 -69 %). The high edible forage yield of the willows relative to pasture (0.8 tDM/ha) during January and April showed that they provided potentially valuable supplements to pasture production. The willows, especially Tangoio, are recommended for use as maintenance fodder for …


The Assimilating And Benefit Of The Chinese Reed Canarygrass (Phalaris Arundinacea L.) On Soil Nutrition, Zhou Bihua, Qi Guang Jun 2024

The Assimilating And Benefit Of The Chinese Reed Canarygrass (Phalaris Arundinacea L.) On Soil Nutrition, Zhou Bihua, Qi Guang

IGC Proceedings (1977-2023)

The Chinese Reed Canarygrass (Phalaris arundinacea L.) is a fine perennial herbage of Gramineae. The wild ripened seeds were collected and sown on the experimental field of the Zhelimu Animal Husbandry College. The former plant of experimental plot is Chinese Crabapple and the cultivating layer is light loam with pH 8.7. The content of nitric N is 33.58 kg/ha, amino N 42.54 kg/ha, organic P 5.6 kg/ha, k 55.97 kg/ha. Clones were set up according to different compositions, that is N, P, K, WP, NPK, CK. the total amount of fertilizer is 23.8 g. The coefficient of absorbing and …


Productivity Of Fodder Beet On Sandy Soil In Egypt, M A. El-Nahrawy, A Z. Abd El-Halim, H S. Oushy Jun 2024

Productivity Of Fodder Beet On Sandy Soil In Egypt, M A. El-Nahrawy, A Z. Abd El-Halim, H S. Oushy

IGC Proceedings (1977-2023)

Farmyard manure effect on the productivity of five fodder beet varieties grown on sandy soil was investigated during three successive seasons. It was revealed from the results that FYM can effectively convert the non-productive sandy soil to a relatively productive soil. FYM application resulted in an increase of 145, 97, 55, 40, 39 and 43% for dry matter. Fresh matter, germination percentage, plant height, root length and root diameter, respectively, averaged over varieties and seasons.


Brachiaria Brizantha Response To Phosphorus Rates In The Nutrient Solution, F A. Monteiro, R A. Martim, W T. Mattos Jun 2024

Brachiaria Brizantha Response To Phosphorus Rates In The Nutrient Solution, F A. Monteiro, R A. Martim, W T. Mattos

IGC Proceedings (1977-2023)

Seven phosphorus rates in the nutrient solution were studied in a greenhouse experiment for Brachiaria brizantha (Hochst) Stapf. Plants had 54 days of growth and 49 days of regrowth. Significant responses in forage yield, tiller number and root dry weight were found. Plant tops were divided into four parts and phosphorus concentration in each one significantly changed with phosphorus rates. Sampling of the young leaf blades and analyzing for phosphorus is proposed for diagnostic purposes. A critical phosphorus concentration of 1.2 g kg-1 is suggested as the critical level in the young leaf blades.


Bahiagrass Forage Production And Quality As Effected By Municipal Biosolids, R M. Muchovej, J E. Rechcigl Jun 2024

Bahiagrass Forage Production And Quality As Effected By Municipal Biosolids, R M. Muchovej, J E. Rechcigl

IGC Proceedings (1977-2023)

Production of biosolids has been increasing consistently in the last few years. Land application of wastes is being regarded as an alternative means of disposal and as a source of inexpensive fertilizer material. Pastures are particularly attractive in this regard since the areas occupied are extensive and large amounts of fertilizer are required for adequate production. The objective of this study is to investigate the effects of various rates of biosolids on bahiagrass yield and quality. Forage samples were collected from each plot from April to December. Significant increases in dry matter production, crude protein content and in vitro digestibility …


Effect Of N And P Fertilizers On Nutritive Value Of Dwarf Elephantgrass (Pennisetum Purpureum) Cv N-75 Mott, J R. Faria, B Gonzalez, J Faria-Marmoll, D E. Morillo Jun 2024

Effect Of N And P Fertilizers On Nutritive Value Of Dwarf Elephantgrass (Pennisetum Purpureum) Cv N-75 Mott, J R. Faria, B Gonzalez, J Faria-Marmoll, D E. Morillo

IGC Proceedings (1977-2023)

Crude protein (CP), Ca and P concentrations and in vitro dry matter digestibility (IVDMD) of irrigated dwarf elephantgrass (Pennisetum purpureum cv. N-75 Mott) as affected by the factorial combination of N (0, 150, 300 and 450 kg N/ha/year) and P (0, 50 and 100 kg P205/ha/year) fertilization was evaluated in a tropical dry forest in Zulia State, western region of Venezuela. A randomized complete block design with three replications was used. Soil was a low-fertility sandy-loam Udic Paleustalf (pH 6.1). Nitrogen fertilization did not influence (P>0.05) any of the variables. Mean CP, IVDMD, Ca and P were: 8.13, …


Effect Of The N And P On Yield And Sward And Dwarf Elephant Grass Pennisetum Purpureum Cv. Mott., J R. Faria, B Gonzalez, J Faria Jun 2024

Effect Of The N And P On Yield And Sward And Dwarf Elephant Grass Pennisetum Purpureum Cv. Mott., J R. Faria, B Gonzalez, J Faria

IGC Proceedings (1977-2023)

The effect of nitrogen and phosphorus application on yield and sward structure as height and leaf, stem and dead forage composition of dwarf elephant grass (Pennisetum purpureum Schumach) cv. Mott was studied under field conditions and complementary irrigation, during one year at very dry tropical forest with a semiarid climate in Venezuela. The nitrogen (N) and Phosphorus (P) rate were 0, 150, 350, 450, kg ha-1 year and 0, 50 and 100 kg P2O5 ha-1 year respectively. The N rate increased the plant height (81.52 cm), leaf, stem and death production (10, 8.13, and 1.62 t DM ha-1 respectively) …


Effects Of Different Phosphate Fertilizers On Pasture Nutrition And Soil Phosphorus In Canterbury, New Zealand, L M. Condron, K M. Goh Jun 2024

Effects Of Different Phosphate Fertilizers On Pasture Nutrition And Soil Phosphorus In Canterbury, New Zealand, L M. Condron, K M. Goh

IGC Proceedings (1977-2023)

A field trial was conducted over 6 years to assess the relative performance of three phosphate (P) fertilisers of differing solubility (single superphosphate, ‘longlife’ superphosphate, ‘reactive’ phosphate rock) on a permanent pasture at Methven in Canterbury, New Zealand. Plant P uptake data showed that while the overall relative effectiveness of the fertilisers was closely related to their water-soluble P content (single superphosphate > ‘longlife’ superphosphate > ‘reactive’ phosphate rock), the agronomic efficiency of the sparingly soluble phosphate rock fertiliser improved markedly with time. Soil P analysis demonstrated that significant dissolution of phosphate rock had occurred in the soil, and the findings of …


Field Evaluation Of Soil Acidity Acidity Effects On The Growth Of Annual And Perennial Ryegrasses, N Miles Jun 2024

Field Evaluation Of Soil Acidity Acidity Effects On The Growth Of Annual And Perennial Ryegrasses, N Miles

IGC Proceedings (1977-2023)

Soil acidity limits pasture establishment and productivity in the moister eastern half of South Africa. Sound lime requirement guidelines based on soil test data are required. In the study reported here, lime responses of annual (Lolium multiflorum) and perennial (Lolium perenne) ryegrasses were evaluated in irrigated field trials located on acidic, highly weathered soils. Annual ryegrass (yield response to lime 27 to 32%) was found to be markedly more tolerant of soil acidity than perennial ryegrass (yield response 68%). Acid saturations of up to 20% had little impact on the yield of annual ryegrass, while yield …


Yield And Quality Of Sugarcane As Affected By Phosphate Applied Cation On Soils Of Various Phosphorus Levels, M A. Matin, K Oya, T Shinjo, T Horiguchi Jun 2024

Yield And Quality Of Sugarcane As Affected By Phosphate Applied Cation On Soils Of Various Phosphorus Levels, M A. Matin, K Oya, T Shinjo, T Horiguchi

IGC Proceedings (1977-2023)

Effects of phosphate application on the growth, yield and quality of sugarcane (Saccharum officinarum L.) were studied on the soils having various phosphorus levels. Superphosphate was applied to bring the available soil P at 5, 15, 25 and 35 mg P2O5 100 g-1 designated as A, B, C and D levels, respectively. Leaf area index (LAI) and dry matter increased on the higher P plots over the lower P plots. The highest cane yield (74 t ha-1) and sugar yield (10.2 t ha- 1) were obtained from the B plot and the lowest cane yield (51 t ha-1) and sugar …


Evaluation Of Different Bradyrhizobium Sp Strains On Nitrogen Fixation Capacity In Four Forage Legumes, F O. Gallardo, E S. Lopes, M C. Diez Jun 2024

Evaluation Of Different Bradyrhizobium Sp Strains On Nitrogen Fixation Capacity In Four Forage Legumes, F O. Gallardo, E S. Lopes, M C. Diez

IGC Proceedings (1977-2023)

Eleven available strains of Bradyrhizobium sp were used to test four forage legumes, Crotalaria juncea (Crotalaria), Cajanus cajans (Guandu), Styzolobium deeriagianum (Mucuna-Ana) and Cyamopsis tetragonoloba (Guar) for symbiotic N-fixation ability. Greenhouse experiments were conducted for nine weeks in order to evaluate shoot, root, and nodule dry weight, nodule number, and shoot nitrogen content. Four strains presented relative nitrogen efficiency (RNE) over 100% with Crotalaria cultivar, whereas only one strain was more efficient with Guandu and Mucuna cultivars. Strain 633 was the only one which presented a high yield with Crotalaria, Guandu and Mucuna-Ana cultivars.


N-P-S Fertilizer Effects On Herbage Yield And Brute Protein Contents In An Irrigated Perennial Pasture In South Patagonia, L San Martino, H M. Espina, E Cittadini Jun 2024

N-P-S Fertilizer Effects On Herbage Yield And Brute Protein Contents In An Irrigated Perennial Pasture In South Patagonia, L San Martino, H M. Espina, E Cittadini

IGC Proceedings (1977-2023)

Little research has been done to determine the effect of fertilization on irrigated pastures in Santa Cruz (South Patagonia). The objective of the present study was to estimate the effects of NPS fertilizing effects on forage yield and quality. The trial was set up in 1994 on a Borolic Haplargid soil characterized by low N content (0.00875% total N), low P availability (9 ppm Olsen) and medium alcalinity (pH 8.4). Pasture was dominated by tall fescue (95%) with 5% of alfalfa. A Complete Radom Design was used and N-P2O5-S nutrients were applied at rates of 120-100-50 kg.ha-1. Monthly mowing began …


Medical School Watercooler Newsletter - June 21, 2024, Lindsey Lyle Jun 2024

Medical School Watercooler Newsletter - June 21, 2024, Lindsey Lyle

Watercooler Newsletter

This is the June 21, 2024 edition of the Frederick P. Whiddon College of Medicine’s newsletter - Watercooler.

Contents Include

  • Prakash named 2024 recipient of the Samuel H. Wilson Award for Studies on DNA Repair
  • M3 students prepare for patient care in the clinical setting
  • Medical student selected to present findings of MS research at national forum
  • Pediatric gastroenterologist joins pediatrics faculty
  • Class of 2026 dons white coats, GHHS inducts new members


Impact Of Physical Intimate Partner Violence On Postpartum Depression And Breastfeeding Duration In American Indian And Alaska Native Women, Zoe Resnick Milavetz Green, Marcia Bennett, Abby Hughes-Scalise, James Theisen, Julie Beans Jun 2024

Impact Of Physical Intimate Partner Violence On Postpartum Depression And Breastfeeding Duration In American Indian And Alaska Native Women, Zoe Resnick Milavetz Green, Marcia Bennett, Abby Hughes-Scalise, James Theisen, Julie Beans

Theses and Graduate Projects

In Alaska, 46 to 91 percent of American Indian and Alaska Native women have experienced physical intimate partner violence (IPV), compared to all women in other states, where the prevalence ranges from seven to 51 percent (Tjaden & Thoennes, 2000). Experiencing physical IPV has negative consequences on the mother’s physical and mental well-being, and has been associated with increased vulnerability to postpartum depression (PPD). Compared to other populations, American Indian and Alaska Native women are at greater risk for PPD due to less access to resources and less research on treatments (MacDorman, 2011). Additionally, American Indian and Alaska Native women …


Evaluation Of A Clincally-Integrated Community Health Worker Program To Support Adults With Cardiovascular Conditions: Guided By The Prism Framework, Cynthia Orofo Jun 2024

Evaluation Of A Clincally-Integrated Community Health Worker Program To Support Adults With Cardiovascular Conditions: Guided By The Prism Framework, Cynthia Orofo

Dissertations

Chronically ill individuals with cardiovascular diseases (CVDs) have been extensively challenged by the complexities of disease management. Cardiovascular disease remains the leading cause of death in the U.S. Although clinically integrated community health worker (cCHW) support interventions have been increasingly implemented to help manage CVDs, a comprehensive analysis of interventions implemented in real-world settings is lacking. The purpose of this study was to observe and evaluate a cCHW support intervention in a real clinical setting serving adults with CVD using an implementation science perspective, guided by the PRISM Framework.


Active Molecular Network Discovery Links Lifestyle Variables To Breast Cancer In The Long Island Breast Cancer Study Project., Miao Yu, Qian Li, Georgia Dolios, Peijun Tu, Susan Teitelbaum, Jia Chen, Lauren Petrick Jun 2024

Active Molecular Network Discovery Links Lifestyle Variables To Breast Cancer In The Long Island Breast Cancer Study Project., Miao Yu, Qian Li, Georgia Dolios, Peijun Tu, Susan Teitelbaum, Jia Chen, Lauren Petrick

Faculty Research 2024

A healthy lifestyle has been associated with decreased risk of developing breast cancer. Using untargeted metabolomics profiling, which provides unbiased information regarding lifestyle choices such as diet and exercise, we aim to identify the molecular mechanisms connecting lifestyle and breast cancer through network analysis. A total of 100 postmenopausal women, 50 with breast cancer and 50 cancer-free controls, were selected from the Long Island Breast Cancer Study Project (LIBCSP). We measured untargeted plasma metabolomics using liquid chromatography-high-resolution mass spectrometry (LC-HRMS). Using the "enet" package, we retained highly correlated metabolites representing active molecular network (AMN) clusters for analysis. LASSO was used …


No Evidence For Metabolic Adaptation During Exercise-Related Energy Compensation, E. W. Flanagan, G. Sanchez-Delgado, C. K. Martin, E. Ravussin, H. Pontzer, L. M. Redman Jun 2024

No Evidence For Metabolic Adaptation During Exercise-Related Energy Compensation, E. W. Flanagan, G. Sanchez-Delgado, C. K. Martin, E. Ravussin, H. Pontzer, L. M. Redman

Clinical Research Faculty Publications

The constrained energy model posits that the increased total daily energy expenditure (TDEE) in response to exercise is often less than the energy cost of the exercise prescribed. The mechanisms behind this phenomenon, coined “exercise-related energy compensation” (ExEC), are poorly understood, and it is unknown if ExEC is coupled with metabolic adaptation. Using a randomized controlled 24-week exercise intervention, individuals who demonstrated ExEC were identified. Changes to all components of TDEE and metabolic adaptation were assessed using doubly labeled water over 14 days and room calorimetry over 24-h 48% of individuals exhibited ExEC (−308 ± 158 kcals/day). There were no …


Transfer Students Matter: A Case Study On The Student Experience Of First-Generation Transfer Students At A Four-Year Public University In A Bridge Program, Quishaundra R. Harris Jun 2024

Transfer Students Matter: A Case Study On The Student Experience Of First-Generation Transfer Students At A Four-Year Public University In A Bridge Program, Quishaundra R. Harris

USF Tampa Graduate Theses and Dissertations

This qualitative study aims to establish a knowledge base and learn about the experience of first-generation transfer students who have completed their Associate in Art (AA) degree from a community college and have transitioned to a four-year public university. The study aims to examine first-generation transfer students' sense of belonging and transition at a four-year public university. A qualitative case study was conducted to learn about the experiences of first-generation transfer students who transferred from state community colleges and are currently enrolled at a four-year university in a bridge program. This study was driven by two theoretical frameworks: Schlossberg's transition …


Improving Anti-Hypertensive Medication Taking: The Direct And Interacting Effects Of Perceived Adherence Difficulty, Adherence Knowledge, And Commitment To Adherence, Yazhen Xiao, Alessandra S. Gessl, Cheryl Nakata, Jelena Spanjol, Stephanie Y. Crawford, Lisa K. Sharp, Anna S. Cui Jun 2024

Improving Anti-Hypertensive Medication Taking: The Direct And Interacting Effects Of Perceived Adherence Difficulty, Adherence Knowledge, And Commitment To Adherence, Yazhen Xiao, Alessandra S. Gessl, Cheryl Nakata, Jelena Spanjol, Stephanie Y. Crawford, Lisa K. Sharp, Anna S. Cui

Business Faculty Publications and Presentations

Background Non-adherence to anti-hypertensive medications is prevalent, leading to increased hospital costs and preventable deaths and disabilities. Managing patient perceptions of adherence difficulties may be key to improving adherence. Objective This study examined the potential negative effect of patients’ perceived difficulties with anti-hypertensive medication taking on adherence, along with whether and how that effect could be reduced through patient knowledge of and commitment to adherence. Method 10,867 adult U.S. residents diagnosed with essential hypertension and prescribed anti-hypertensive medications participated in a cross-sectional online survey using self-reported behaviors and perceptions. Stepwise regressions and mean difference analyses were performed. Results Perceived adherence …


Toxicosis From Range Lupine Ingestion In A Research Herd Of Rafter 7 Merino Sheep, Benjamin J. Weigler, Walter F. Mandeville Iii, Scott Huber, Gary Mccuin, Fabrizio Caragena, Daniel D. Cook, Stephen T. Lee, Chris A. Pritsos Jun 2024

Toxicosis From Range Lupine Ingestion In A Research Herd Of Rafter 7 Merino Sheep, Benjamin J. Weigler, Walter F. Mandeville Iii, Scott Huber, Gary Mccuin, Fabrizio Caragena, Daniel D. Cook, Stephen T. Lee, Chris A. Pritsos

Poisonous Plant Research (PPR)

An outbreak of lupine alkaloid neurotoxicosis and death occurred in sheep grazed on rangeland areas of the Nevada Great Basin during the summer of 2023. Overall, 97 sheep died despite veterinary supportive care. Lupinus argenteus var. utahensis was implicated as the causative plant with high levels of lupanine (11.5 µg/mg) and spartiene (13.7 µg/mg) in collected and archived samples. Previous reports of sheep deaths due to lupine ingestion have not been recorded in this region. An increased abundance of the number plants producing seed pods having a high alkaloid content may have been associated with abnormally elevated levels of precipitation …


Novel Adaptations In Iron Regulation Acquired During Chronic Fungal Cf Infections, Daniel R. Murante Jun 2024

Novel Adaptations In Iron Regulation Acquired During Chronic Fungal Cf Infections, Daniel R. Murante

Dartmouth College Ph.D Dissertations

Chronic fungal infections are highly recalcitrant to treatment; we postulated that as populations persist, increasing genetic diversity is reflected in phenotypic heterogeneity, contributing to treatment inefficacies. The study of evolutionary patterns is underrepresented in chronic fungal infections, and to supplement this body of knowledge, we leveraged isolates acquired from four individuals with chronic fungal-dominated cystic fibrosis infections. We evaluated in-host evolution through a whole-genome sequencing approach, comparing multiple isolates obtained from each subject's sputum and bronchoalveolar lavage fluid. Our analysis found non-synonymous mutations that arose in parallel across the independent infections in the gene MRS4, which encodes a mitochondrial …


Application And Development Of Ceragenins In Medical Device Coatings For Clinical Settings, Elliot E. Sherren Jun 2024

Application And Development Of Ceragenins In Medical Device Coatings For Clinical Settings, Elliot E. Sherren

Theses and Dissertations

Hospital-acquired infections (HAIs) pose a significant and increasing threat to global health. One primary cause of this threat is increasing antibiotic resistance. As traditional antibiotics continue to grow less effective, there is an urgent need for novel antimicrobial strategies. This work explores the potential of ceragenins, also known as cationic steroid antimicrobials (CSAs), as a promising alternative to combat HAIs. Specifically, we investigated potential roles that CSAs can play in the context of multiple medical device coatings in healthcare settings. Ceragenins are synthetic mimic of antimicrobial peptides (AMPs) which exhibit broad-spectrum antimicrobial activity against many common pathogens that have been …