Digital Commons Network^™

Understanding The Effectiveness Of Lifestyle Changes In Women With Gestational Diabetes Mellitus, Arianne Ortega, Michele Shaw

NURS 404/406 Research & Info Management

PICOT Research Question: How does lifestyle impact diabetes in pregnant women?

Implementation And Evaluation Of A Neonatal Resucitation Program Protocol In Stand-Alone Emergency Department, Hannah Collins Walden

Doctor of Nursing Practice Scholarly Projects

Problem statement: Within nursing there are some skills that hold a significant amount of risk. This includes neonatal resuscitation within stand-alone emergency departments. Due to the low frequency of opportunities to practice neonatal resuscitation, nurses must utilize alternative methods to maintain current evidence-based practice. Purpose: The purpose of this project was to evaluate the effectiveness of a protocol incorporating Neonatal Resuscitation Program (NRP) preparedness and simulation to increase stand-alone emergency department nurses’ perceived clinical competence to performing neonatal resuscitation. Methods: The development and implementation of a protocol that defines and incorporates NRP roles, provides a maintenance checklist for …

Implementing The 5a’S Of Obesity Management In Primary Care, Holly H. Rowell

Doctor of Nursing Practice Scholarly Projects

Problem Statement: The prevalence of obesity continues to increase globally, with greater prevalence in the southern United States, resulting in higher costs to the healthcare system and greater risks for the development of other chronic diseases. Purpose: Determine if implementing the 5A’s of Obesity Management among primary care providers in a rural, low-income healthcare setting will increase the diagnosis of obesity and result in a subsequent decrease in weight among patients who are obese. Methods: An educational session was held to familiarize providers with the 5A’s of Obesity Management and the importance of obtaining and documenting proper height …

Impact Of Hydrogen Peroxide Wipes Disinfecting Clostridioides Difficle On High-Touch Surfaces, Tyler Wolf Ramirez

Doctor of Nursing Practice Scholarly Projects

Clostridioides difficile is the leading cause of nosocomial diarrheas worldwide (Centers for Disease Prevention and Control [CDC], 2022). 15% of all hospitalized patients in the United States develop antibiotic-associated diarrhea (AAD), with 15-25% of cases caused by C. difficile (CDC, 2022). C. difficile costs the United States Healthcare system $5.4-6.3 billion annually (Balsells et al., 2019). The project’s purpose was to see if implementing hydrogen peroxide (H2O2) wipes using an interprofessional team leads to the following expected outcome(s): reduction in hospital-acquired C. difficile infections and comparable disinfection rates to sodium hypochlorite. An interprofessional team consisting of the primary lead, Clinical …

Development Of Anti-Fibrotic Agents For Potential Use In Glaucoma Filtration Surgery To Prevent Scar Formation, Nikhala Shree S

Theses and Dissertations

Glaucoma is the second leading cause of blindness with irreversible vision loss. It is marked by the degeneration of retinal ganglion cells, which results in optic nerve head damage. Intraocular pressure (IOP) is a prime risk factor of glaucoma controlled by various treatment regimens i.e., medication, laser, and/ or surgery. It is reported that longterm exposure to anti-glaucoma medications (AGM) may subtle the surgical success rate leading to postoperative fibrosis. Transforming growth factor beta (TGF-β) is a growth factor that plays an important role in the development of glaucoma and promotes fibrosis.

This study is aimed at developing peptides to …

Tech Note 2024-1 A Novel Framework To Estimate Social And Private Value Created Through Commercialization Of A Pharmaceutical Product, Paula Chaves De Silva, Fred D. Ledley

CISI Publication

This framework posits that the value created by a new medicine is embodied in the total health value (health benefit) provided to those using the products. This value is then distributed between social value and private value by the price paid for the product and how these revenues are expensed for different purposes. In this framework, the social value created includes the residual health value (net price paid) along with the scientific value, jobs creation, and social payments to public sector organizations. The private value created includes shareholder value (change in market capitalization plus cash distributions to shareholders) as well …

Comes In Waves: Clinical Overview Of Vibrio Species, Natalie M. Prosser, Ms

Student Papers, Posters & Projects

Earth’s oceans, despite their beauty and vast ecosystems, pose numerous threats to marine life and humans living along the coastline. Vibrio species (spp.) is a common species of oceanic bacteria native to coastal and brackish waters. This bacterium is capable of causing various degrees of human disease among different populations. Three clinically significant species of Vibrio include Vibrio vulnificus, Vibrio parahaemolyticus, and Vibrio cholera; all three species share virulence factors, but each are capable of causing varying degrees of vibriosis infections. Vibriosis infections include but are not limited to wound infections, necrotizing fasciitis, and gastroenteritis. In particular, …

The Correlation Of Human Leukocyte Antigen (Hla) Haplotypes With Clinical And Laboratory Profiles Of Celiac Disease In Children, Raghad Dawood, Raghad Najem, Arabiya Ali, Rabab Farhan

Iraqi Postgraduate Medical Journal

Background:Celiac disease is an immune-mediated enteropathy triggered by the ingestion of gluten in genetically susceptible individuals. Gluten is the major protein component of wheat, rye, and barley, the major predisposing genes are the HLA-DQ2 and DQ8 genotypes found in at least 95% of patients. Achieving early diagnosis of coeliac disease is critical to ensuring good lifelong health and providing children with the ability to thrive .Objective:To demonstrate the profiles of coeliac disease (the way in which coeliac disease present , to find out age and sex distribution , endoscopical and histopathological finding) and to analyze the correlation of HLA haplotypes …

Application Of Clavien-Dindo Classification System In The Early Complications Of Radical Cystectomy In Al-Yarmook Teaching Hospital, Ahmed Abbass Al-Sadie, Saad Al-Sammarraie, Taha Kadhum

Iraqi Postgraduate Medical Journal

BACKGROUND: The most effective treatment for muscle-invasive bladder cancer and non-muscle invasive bladder cancer with highest risk of progression, is Radical cystectomy and urinary diversion. This operation carries                  a high risk of complications of multiple types that can affect not only the urinary system but also other systems. OBJECTIVE: This study analyzes the early complications (within 30 days) of Radical Cystectomy and urinary diversion, using a standardized classification system i.e. Clavien-Dindo classification system. PATIENTS AND METHODS: This is a combined retrospective and prospective study analyzing the early complications of RC.                    We review the early (30 days) post-operative period retrospectively for …

Beyond Four Walls: Outdoor Recess As A Complement To Classroom Engagement, Valerie Mulvenna

School of Education and Leadership Student Capstone Theses and Dissertations

This mixed-methods study examined the impact of increased outdoor recess on elementary students' classroom engagement following the implementation of Illinois' 2021 The Right to Play Every Day Act. The study is driven by two main research questions: (1) Does increased outdoor recess influence a student’s classroom engagement? (2) What are educators' perspectives on the implementation of the Act? Quantitative data was collected through classroom observations of 16 third-grade students over six weeks, measuring on-task behavior before and after recess periods. Qualitative data was gathered through semi-structured interviews with five elementary educators. While statistical analysis yielded inconclusive results regarding the relationship …

Can Nutrition Education Reduce Division Iii Female Athlete's Risk Of Developing Low Energy Availability, Coby Stover

Masters Theses/Capstone Projects

Context: Low Energy availability (LEA) is widely acknowledged as a state in which an individual does not have sufficient energy to support normal functions within the body after energy has been expended through exercise. In sports environments, athletes can exhibit LEA for a variety of reasons. These reasons range from improper food intake to effectively fuel and re-fuel their body for the energy demands of their specific sport, to eating disorders (ED) and eating disorder behaviors. Access to appropriate nutrition knowledge is also a major factor that can place athletes at risk for developing LEA. Both males and females …

Report On Findings From Household Needs Study, Paulin T. Straughan, Mathew Mathews

ROSA Research Briefs

The Household Needs Study (HNS) aimed to capture public perspectives on essential items and activities that are deemed necessary for a normal life in Singapore and to understand the extent to which Singaporeans are able to access these items and activities. To do so, the study adopted the Living Standards Approach (Saunders, Naidoo & Wong, 2022), which purports that individuals experience relative deprivation and/or social exclusion if they do not have access to items and activities that are deemed to be essential by society. In this study, a survey was conducted with a nationally representative sample of around 4,000 respondents …

Wooster Magazine: Summer 2024, Caitlin Paynich Stanowick

Wooster Magazine: 2021-2030

In the summer 2024 issue of Wooster magazine students and alumni share what inspired their capstone scholarship at Wooster and where it led them. The Class of 2024 drew from their own interests to design scholarly research and creative expression unique to them; students featured include Athena Tharenos, Levi Gainer, Briana Mosley, Corey Knauf, and Tyara Thompson. For some students, I.S. uncovers a wonder and eagerness to further their study in the area. This issue also shares the stories of alumni who built upon the foundation of their I.S. for ongoing research, professional work, and everyday inspiration including John Trainor …

Type-2 Diabetes, Pancreatic Amylin, And Neuronal Metabolic Remodeling In Alzheimer's Disease, Noah Leibold, James R. Bain, Florin Despa

Neurology Faculty Publications

Type-2 diabetes raises the risk for Alzheimer’s disease (AD)-type dementia and the conversion from mild cognitive impairment to dementia, yet mechanisms connecting type-2 diabetes to AD remain largely unknown. Amylin, a pancreatic 𝜷-cell hormone co-secreted with insulin, participates in the central regulation of satiation, but also forms pancreatic amyloid in persons with type-2 diabetes and synergistically interacts with brain amyloid 𝜷 (A𝜷) pathology, in both sporadic and familial Alzheimer’s disease (AD). Growing evidence from studies of tumor growth, together with early observations in skeletal muscle, indicates amylin as a potential trigger of cellular metabolic reprogramming. Because the blood, cerebrospinal fluid, …

Surface Roughness And Stain Remover Ability Of Prophylaxis Paste And Biochar Gel For Stained Teeth Based On Cucurbita Moschata – In Vitro Study, Shadwa Kabil

Dentistry

No abstract provided.

Surface Roughness And Stain Remover Ability Of Prophylaxis Paste And Biochar Gel For Stained Teeth Based On Cucurbita Moschata – In Vitro Study, Shadwa Kabil, Mohamed Mostafa Zayed, Mayssa Abdel Hady Mohamed, Elsayed Gamal Zaki Swelame, Shaimaa Moustafa Rohym

Dentistry

No abstract provided.

Examining Dietary Disparities And Associated Factors Among Young Children Across Diverse Racial, Ethnic And Immigrant Households In Nebraska, Naveta Bhatti

College of Education and Human Sciences: Dissertations, Theses, and Student Research

Early childhood is a crucial stage for developing eating behaviors which in turn plays a major role in determining health outcomes. Assessing children’s diet plays a crucial role in tackling the obesity epidemic. One of the ways to assess children’s dietary intake is by evaluating their dietary quality. Dietary quality refers to the overall healthfulness and nutritional value of an individual's diet, considering the combination of foods consumed over time. Research has consistently demonstrated that a high-quality diet is associated with a reduced risk of several health issues, such as all-cause mortality, cardiovascular disease incidence or mortality, cancer incidence or …

The Influence Of Student-Teacher Relationship Quality On Educational Outcomes For Students With Attention-Deficit/Hyperactivity Disorder, Cassidy Ann Spradlin

Dissertations and Doctoral Documents, University of Nebraska-Lincoln, 2023–

The purpose of this dissertation study was to examine the associations between student-teacher closeness, student-teacher conflict, and educational outcomes (i.e., academic, social, and behavioral outcomes) for students with elevated symptoms of attention-deficit/hyperactivity disorder (ADHD). Positive student-teacher relationship quality is linked to educational success and has been found to be inversely related to adverse outcomes in the general population. Previous research has examined differences in student-teacher relationship quality for students with ADHD, but the association between student-teacher relationship quality and educational outcomes is not well understood for students with ADHD. This dissertation study examined the association between student-teacher relationship quality and …

Performance Fatigability And Neuromuscular Responses During And After One Set Of Forearm Flexion Muscle Actions To Failure At 30% Versus 70% One-Repetition Maximum In Men And Women, Tyler Joseph Neltner

Dissertations and Doctoral Documents, University of Nebraska-Lincoln, 2023–

Previous studies have examined sex differences in performance fatigability during isometric, isokinetic and controlled dynamic constant external resistance (DCER) fatiguing tasks (FT), however, whether those sex differences remain during maximal intended velocity (MIV) DCER muscle actions remains unclear. The purpose of this study was to examine the sex-related differences in the time course of fatigue, neuromuscular responses, and coactivation from the ipsilateral and contralateral limbs during MIV DCER muscle actions to failure at low versus high relative loads, as well as performance fatigability from pre- to post-testing. Twenty-seven college-aged men (n = 14) and women (n = 13) …

Manipulations Of The Caenorhabditis Elegans Microbiome Reveal Influences Of Detrimental Members On Host Life History Traits, Ashley Elizabeth Foltz

Dissertations and Doctoral Documents, University of Nebraska-Lincoln, 2023–

Microbiomes are a fundamental part of eukaryotic organisms and play a role in both host health and fitness. Although microbiomes are often associated with health and positive effects on the host, certain microbiome compositions are also associated with disease. We used Caenorhabditis elegans and its experimental microbiome, CeMbio to explore the interactions that individual microbiome members have with other microbes, with the host, and how the entire microbiome community interacts with the host. We found that individual CeMbio members have varying effects on host health and fitness compared to the whole community. This suggested that there is synergy occurring in …

Genetically Modified Bovine Milk-Derived Small Extracellular Vesicles In Drug Delivery, Alice Kah Hui Ngu

Dissertations and Doctoral Documents, University of Nebraska-Lincoln, 2023–

Small extracellular vesicles (SEVs, “exosomes”) are natural nanoparticles that can be endogenously synthesized and also obtained from dietary sources, such as bovine milk SEVs (mEVs). mEVs have been extensively studied and discovered with contributive features that potentially play a role in drug delivery and other therapeutic purposes, such as diagnostic tools. Current studies have shown that mEVs have been used preclinically to carry in targeting drugs, nucleotides, biomolecules, and labels to target metabolic diseases and cancers. Extensive studies have focused on further modifying SEVs to enhance their versatility in pharmaceutical use. In this dissertation, we exhibited one of the ways …

Virtual Fencing In Livestock Management: Effects On Beef Cattle Stress And Enhancing Wildlife Conservation, Kaitlyn E. Dozler

School of Natural Resources: Dissertations, Theses, and Student Research

I examined the effects of virtual fencing on beef cattle stress and how implementing the technology can aid wildlife habitat conservation at the University of Nebraska Gudmundsen Sandhills laboratory (GSL) near Whitman, NE. First, I examined how virtual fencing influences acute heart rate changes in beef cattle fitted with the virtual fencing collars. No significant difference in the average heart rate of a cow (P > 0.05) was observed between the 30 min control and virtual fenced periods for both trial dates. Second, I examined the influence of topography on wildlife species richness and presence at GSL using wildlife camera …

Open Repository @ Binghamton Monthly Additions And Top Downloads - June 2024, Caitlin Holton

Library Created Resources

Newly added work in the Open Repository @ Binghamton (ORB) from 6/1/2024-6/30/2024. Top downloads from same time frame.

Music Education In The Urban Classroom: Issues Of Equity And Access, Lakeisha Walker

Theses

Music education in urban classrooms plays a crucial role in shaping students' overall development and academic success. The field of music education is not immune to the challenges of equity and access that exist in urban settings. It is essential to address these issues to ensure that all students have equal opportunities to participate in music programs and reap the countless benefits that come with them.

The importance of this topic in the field of music education cannot be overstated. Research has shown that students who participate in music programs demonstrate improved academic performance, enhanced cognitive skills, and increased creativity. …

Summer 2024 Graduation Survey Responses, Systems Intelligence And Data Analytics, University Of Nebraska At Omaha

Graduation

Summer 2024 Graduation survey responses master file without identifiers.

Menstrual Hygiene Amongst School Girls: Still A Messy Business, Naghma Rizvi, Saleema A. Gulzar, Tazeen S. Ali, Syeda Aleena Fazal, Alishah Aziz Gulzar, Yasmin Parpio, Rimsha Hirani

Journal of Asian Midwives (JAM)

Background: Menstruation has become a taboo topic among adolescent females, affecting their reproductive health, particularly in more traditional South Asian nations such as Pakistan. The study highlights the societal silence surrounds menstruation, which leads to detrimental practices and attitudes among school-age females. The study reveals the sociocultural, psychological, and educational challenges that teenagers encounter. The presence of myths and misconceptions adds to unsanitary habits, which undermine education and reproductive health.
Methodology: A descriptive cross-sectional study was conducted in urban Karachi. The participants were 850 unmarried school-going female adolescents aged 13 to 19. The data were collected using a pre-coded questionnaire. …

Use Of Social Media For Receiving Professional Support In Enhancing Mothers’ Lactation Self-Efficacy, Mehtab Lalwani, Zohra Kurji, Salma Rattani, Zahra Shaheen, Hussain Maqbool Ahmed Khuwaja, Shabina Ariff

Journal of Asian Midwives (JAM)

Background: Insufficient support for breastfeeding and limited exclusive breastfeeding rates emphasize the need for high-impact approaches to enhance maternal confidence in lactation. Social media has emerged as a promising platform for professional support and information dissemination in this context. This review aims to examine the role of social media in providing professional lactation support to mothers in enhancing their lactation self-efficacy.
Method: Employing PRISMA guidelines, the review sought relevant literature on professional assistance in enhancing breastfeeding self-efficacy. Major databases, including PubMed, CINAHL, Google Scholar, and Science Direct, were meticulously queried using targeted keywords. Every selected article underwent screening for English …

Enhancing Maternal And Fetal Well-Being: Exploring The Determinants Of Preconception Care, Mahak Mehdi Hashim Mehdi Hashim, Nurmeen Anwar Ali

Journal of Asian Midwives (JAM)

Preconception care is the delivery of biomedical, behavioral, and social health interventions to women and couples of reproductive ages. The significance of care is emphasized by the World Health Organization (WHO), as it greatly affects the quality of life of the mother and child. However, the uptake of pre-conception care services in Low and Middle-income countries (LMIC) such as Pakistan is low due to several factors. This discussion paper will identify some of the contextual factors related to the quality of health care services, acceptability due to cultural value beliefs, and affordability that largely influence the utilization of preconception care …

Efficacy And Safety Of Odevixibat In Patients With Alagille Syndrome (Assert): A Phase 3, Double-Blind, Randomised, Placebo-Controlled Trial., Nadia Ovchinsky, Madeleine Aumar, Alastair Baker, Ulrich Baumann, Philip Bufler, Mara Cananzi, Piotr Czubkowski, Özlem Durmaz, Ryan T. Fischer, Giuseppe Indolfi, Wikrom W. Karnsakul, Florence Lacaille, Way S. Lee, Giuseppe Maggiore, Philip Rosenthal, Mathias Ruiz, Etienne Sokal, Ekkehard Sturm, Wendy Van Der Woerd, Henkjan J. Verkade, Andrew Wehrman, Christine Clemson, Qifeng Yu, Quanhong Ni, Jessica Ruvido, Susan Manganaro, Jan P. Mattsson

Manuscripts, Articles, Book Chapters and Other Papers

BACKGROUND: In patients with Alagille syndrome, cholestasis-associated clinical features can include high serum bile acids and severe pruritus that can necessitate liver transplantation. We aimed to evaluate the efficacy and safety of the ileal bile acid transporter inhibitor odevixibat versus placebo in patients with Alagille syndrome.

METHODS: The ASSERT study was a phase 3, double-blind, randomised, placebo-controlled trial that enrolled patients at 21 medical centres or hospitals in ten countries (Belgium, France, Germany, Italy, Malaysia, the Netherlands, Poland, Türkiye, the UK, and the USA). Eligible patients had a genetically confirmed diagnosis of Alagille syndrome, a history of significant pruritus, and …

Juvenile Polyposis Syndrome In Children: The Impact Of Smad4 And Bmpr1a Mutations On Clinical Phenotype And Polyp Burden., Shlomi Cohen, Anat Yerushalmy-Feler, Isabel Rojas, Claudia Phen, David A. Rudnick, Colleen B. Flahive, Steven H. Erdman, Ramit Magen-Rimon, Ivana Copova, Thomas M. Attard, Andrew Latchford, Warren Hyer

Manuscripts, Articles, Book Chapters and Other Papers

OBJECTIVE: A constitutional disease-causing variant (DCV) in the SMAD4 or BMPR1A genes is present in 40%-60% of patients with juvenile polyposis syndrome (JPS). The aim of this study was to characterize the clinical course and polyp burden in children with DCV-positive JPS compared to DCV-negative JPS.

METHODS: Demographic, clinical, genetic, and endoscopic data of children with JPS were compiled from eight international centers in the ESPHGAN/NASPGHAN polyposis working group.

RESULTS: A total of 124 children with JPS were included: 69 (56%) DCV-negative and 55 (44%) DCV-positive (53% SMAD4 and 47% BMPR1A) with a median (interquartile range) follow-up of 4 (2.8-6.4) …