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Gender Effect On Torque And Explosive Characteristics At Knee Extensor In Triathletes With High And Low Eating Attitudes, Xin-Cen Wen, Wei-Chun Hsu, Li-Xin Tang, Ting-En Li, Jo-Yu Chung, Yi-Jia Lin Jul 2024

Gender Effect On Torque And Explosive Characteristics At Knee Extensor In Triathletes With High And Low Eating Attitudes, Xin-Cen Wen, Wei-Chun Hsu, Li-Xin Tang, Ting-En Li, Jo-Yu Chung, Yi-Jia Lin

ISBS Proceedings Archive

This study examined the impact of eating attitudes on the strength, agility, explosiveness, and endurance performance of 26 triathletes who were categorized into EAT-Better and EAT-Worse groups. Isometric knee extensor maximal voluntary contractions were conducted before and after cycling incremental VO2 max tests. Results showed that there were no significant between-group differences at baseline and there were gender differences in Peak Knee Extensor Joint Torque and Knee Extensor Joint Impulse. At fatigue status, only females exhibited a decrease in fatigue-induced Knee Joint Impulse. Although there were no significant between-group differences in fatigue status, EAT-Worse exhibited a more notable decrease than …


Tibial Load In Runners With A History Of Bone Stress Injury: A Case Control Study, Megan A. Peach, James Becker, Kaitlyn Mckibben Jul 2024

Tibial Load In Runners With A History Of Bone Stress Injury: A Case Control Study, Megan A. Peach, James Becker, Kaitlyn Mckibben

ISBS Proceedings Archive

The purpose of this study was to identify differences in tibial bone load during running in subjects with a history of bone stress injury (BSI) as compared to healthy controls. Subjects with a recent history of tibial BSI (n=3), >1 year since tibial BSI (n=3), and healthy controls (n=3) ran on an instrumented treadmill while motion capture data was collected. Mixed model ANOVA (p1 year since tibial BSI. While a relationship between time and bone load post tibial BSI is possible based on the results of this study, additional studies are essential to confirm this association and progress our understanding …


The Relationship Between Neurocognition And Side-Step Cutting Biomechanics In Women’S Australian Football Players, Tess L. Rolley Miss, Natalie Saunders, Ashlee Hendy Mrs, Brendan Major Mr, Alicia Goodwill Mrs, Sandy Shultz Mr, Aaron Fox Mr Jul 2024

The Relationship Between Neurocognition And Side-Step Cutting Biomechanics In Women’S Australian Football Players, Tess L. Rolley Miss, Natalie Saunders, Ashlee Hendy Mrs, Brendan Major Mr, Alicia Goodwill Mrs, Sandy Shultz Mr, Aaron Fox Mr

ISBS Proceedings Archive

Despite increased awareness and targeted efforts, anterior cruciate ligament (ACL) injuries continue to frequently occur within the women’s Australian-rules football league (AFLW). AFLW ACL injuries frequently occur when performing a defensive side-step cut. Considering the reactive nature of this scenario, neurocognitive function may be an important risk factor. Therefore, the purpose of this study was to investigate the relationship between neurocognition and side-step cutting biomechanics in women’s Australian football players. Relationships between neurocognitive measures and 3D knee loads during unanticipated side-stepping were examined. No statistically significant relationships were found. These findings provide recommendations for future research to explore different cognitive …


Overweight And Underweight Implements’ Impact On Critical Factors Of Rotational Shot-Putting Technique, Leah N. Klein, James Becker, Justin Whitten, Megan Peach Jul 2024

Overweight And Underweight Implements’ Impact On Critical Factors Of Rotational Shot-Putting Technique, Leah N. Klein, James Becker, Justin Whitten, Megan Peach

ISBS Proceedings Archive

The purpose of this study was to evaluate the impacts of heavy and light implements on the kinematics of the rotational shot put technique. Ten collegiate shot putters completed three rotational shot put attempts using competition, overweight and underweight implements. Whole body kinematics were recorded on each throw to evaluate key aspects of shot putting technique including pelvis-torso separation, rear leg hip flexion, rear leg knee flexion, and peak pelvis angular velocity during specific phases of the throw. Results of this study highlight that when using an overweight implement, athletes have significantly less hip flexion compared to the competition-weighted implement …


Association Between Morphology And Hip And Knee Joint Reaction Forces During Running In American Football Players: Implications For Osteoarthritis Development, Monique Mokha, Sean Mcbride, Jacob Haberer, Johnathan Polletta, Nicole Branum, Marissa Bonsangue, Andrew Schafer, Jack Stensland, Nivene Hojeij, Elie Christoforides Jul 2024

Association Between Morphology And Hip And Knee Joint Reaction Forces During Running In American Football Players: Implications For Osteoarthritis Development, Monique Mokha, Sean Mcbride, Jacob Haberer, Johnathan Polletta, Nicole Branum, Marissa Bonsangue, Andrew Schafer, Jack Stensland, Nivene Hojeij, Elie Christoforides

ISBS Proceedings Archive

National Football League (NFL) American football players are exposed to osteoarthritis risk factors of obesity and high joint loads. We sought to examine the association between total body mass (TBM), lean body mass (LBM), body fat percent (BFP), peak compressive hip and knee joint reaction forces (JRF), and vertical ground reaction forces (vGRF) in NFL draft eligible players during a high-speed run. One-hundred twenty-five participants ran at 6.5 m/s for 5 sec on an instrumented treadmill. Results showed moderate to low significant negative associations between TBM, LBM, and vGRF and hip and knee compression JRF. There was a negligible significant …


The Effect Of The Difference In Resistance Training Velocity Loss On Muscular Strength And Explosive Performance, Chenfu Huang, Li-Fu Cheng Jul 2024

The Effect Of The Difference In Resistance Training Velocity Loss On Muscular Strength And Explosive Performance, Chenfu Huang, Li-Fu Cheng

ISBS Proceedings Archive

The present study aimed to compare the effects of mixed-training with different proportions of concentric velocity loss (10% vs. 30%) on muscular strength and explosive performance. Twenty healthy trained men were recruited and randomly assigned to the velocity loss of 10% (VL10) and velocity loss of 30% (VL30) for eight weeks of mixed-training. The participants performed 1RM in back squat, countermovement jump (CMJ), 10-m (T10) and 20-m (T20) sprint running before and after mixed-training. Both groups showed similar improvement in the 1RM strength (9.6% vs 9.3%). However, only the VL10 group significantly improved CMJ (6.2%), T10 (-1.7%), and T20 (-1.3%) …


Machine Learning Approaches For Identification Of Parkinson’S Disease Severity Using Multimodal Features, Hwayoung Park, Changhong Youm, Bohyun Kim, Hyejin Choi, Juseon Hwang, Minsoo Kim Jul 2024

Machine Learning Approaches For Identification Of Parkinson’S Disease Severity Using Multimodal Features, Hwayoung Park, Changhong Youm, Bohyun Kim, Hyejin Choi, Juseon Hwang, Minsoo Kim

ISBS Proceedings Archive

This study aimed to create a digital biomarker for assessing the severity of Parkinson's disease (PD) using multimodal features from 50 PD patients and 50 healthy controls. They underwent clinical tests, gait analysis using a motion capture system, postural and functional evaluations, and lifestyle questionnaires. These multimodal features underwent dimensionality reduction techniques such as logistic regression and principal component analysis to identify PD severity using the MDS-UPDRS total score. The results developed six models using machine learning algorithms (Linear Regression and Random Forest), with Model 1 performing the best; spatiotemporal variables from gait analysis were crucial in identifying PD severity. …


Making Space For Yeast: Toward A Zymurpolitics, Walter W. Furness Jul 2024

Making Space For Yeast: Toward A Zymurpolitics, Walter W. Furness

The Geographical Bulletin

Geographic scholarship on craft brewing has characteristically fixated on place as a lens through which to understand and valuate ostensibly “local” beer, wherein fermentation acts as an alchemistic shorthand, transmuting far-flung ingredients into a product emphatically rooted in a particular location. However, yeast tends to receive little attention in this literature, even though it is a primary agent (alongside humans) in acting on raw materials to produce beer. Defying the notion of “hyperlocal,” yeast is frequently sourced from distant laboratories, though some breweries maintain their own cultures in-house. This paper draws on existing literature, observation, and interviews with brewers to …


Dining Out With Allergies: Examining Boston’S Allergy-Friendly Restaurant Landscape, Rebecca Marie Shakespeare Jul 2024

Dining Out With Allergies: Examining Boston’S Allergy-Friendly Restaurant Landscape, Rebecca Marie Shakespeare

The Geographical Bulletin

According to a recent national survey, about ten percent of American adults, estimated 26 million, are likely to have food allergies (Gupta, et al. 2019). Food allergies have many psychosocial outcomes for adults, including social isolation, anxiety, and loneliness. Framing restaurants as a site of social engagement, this article seeks to describe the restaurant landscape for adults with food allergies in Boston. Using online user reviews from TripAdvisor and AllergyEats to identify locations of restaurants with mostly positive allergy-related reviews, this paper uses GIS to assess the geographic accessibility of allergy-friendly restaurants for locations across Boston. Reported allergy-friendly restaurants tend …


27-Hydroxycholesterol Acts On Estrogen Receptor Α Expressed By Pomc Neurons In The Arcuate Nucleus To Modulate Feeding Behavior, Hui Ye, Xiaohua Yang, Bing Feng, Pei Luo, Valeria C.Torres Irizarry, Leslie Carrillo-Sáenz, Meng Yu, Yongjie Yang, Benjamin P. Eappen, Marcos David Munoz, Nirali Patel, Sarah Schaul, Lucas Ibrahimi, Penghua Lai, Xinyue Qi, Yuliang Zhou, Maya Kota, Devin Dixit, Madeline Mun, Chong Wee Liew, Yuwei Jiang, Chunmei Wang, Yanlin He, Pingwen Xu Jul 2024

27-Hydroxycholesterol Acts On Estrogen Receptor Α Expressed By Pomc Neurons In The Arcuate Nucleus To Modulate Feeding Behavior, Hui Ye, Xiaohua Yang, Bing Feng, Pei Luo, Valeria C.Torres Irizarry, Leslie Carrillo-Sáenz, Meng Yu, Yongjie Yang, Benjamin P. Eappen, Marcos David Munoz, Nirali Patel, Sarah Schaul, Lucas Ibrahimi, Penghua Lai, Xinyue Qi, Yuliang Zhou, Maya Kota, Devin Dixit, Madeline Mun, Chong Wee Liew, Yuwei Jiang, Chunmei Wang, Yanlin He, Pingwen Xu

Division of Basic Science Faculty Publications

Oxysterols are metabolites of cholesterol that regulate cholesterol homeostasis. Among these, the most abundant oxysterol is 27-hydroxycholesterol (27HC), which can cross the blood-brain barrier. Because 27HC functions as an endogenous selective estrogen receptor modulator, we hypothesize that 27HC binds to the estrogen receptor α (ERα) in the brain to regulate energy balance. Supporting this view, we found that delivering 27HC to the brain reduced food intake and activated proopiomelanocortin (POMC) neurons in the arcuate nucleus of the hypothalamus (POMCARH) in an ERα-dependent manner. In addition, we observed that inhibiting brain ERα, deleting ERα in POMC neurons, or chemogenetic inhibition of …


An International Multidisciplinary Consensus On Pediatric Metabolic Dysfunction-Associated Fatty Liver Disease, Le Zhang, Mortada El-Shabrawi, Louise A. Baur, Christopher D. Byrne, Giovanni Targher, Mohit Kehar, Gilda Porta, Way Seah Lee, Sander Lefere, Serap Turan, Anna Alisi, Ram Weiss, Maria Felicia Faienza, Ambika Ashraf, Shikha S. Sundaram, Anshu Srivastava, Ruth De Bruyne, Yunkoo Kang, Flora Bacopoulou, Yong Hai Zhou, Andy Darma, Monica Lupsor-Platon, Masahide Hamaguchi, Anoop Misra, Nahum Méndez-Sánchez, Nicholas Beng Hui Ng, Claude Marcus, Amanda E. Staiano, Nadia Waheed, Saleh A. Alqahtani, Cosimo Giannini, Ponsiano Ocama, Mindie H. Nguyen, Maria Teresa Arias-Loste Jul 2024

An International Multidisciplinary Consensus On Pediatric Metabolic Dysfunction-Associated Fatty Liver Disease, Le Zhang, Mortada El-Shabrawi, Louise A. Baur, Christopher D. Byrne, Giovanni Targher, Mohit Kehar, Gilda Porta, Way Seah Lee, Sander Lefere, Serap Turan, Anna Alisi, Ram Weiss, Maria Felicia Faienza, Ambika Ashraf, Shikha S. Sundaram, Anshu Srivastava, Ruth De Bruyne, Yunkoo Kang, Flora Bacopoulou, Yong Hai Zhou, Andy Darma, Monica Lupsor-Platon, Masahide Hamaguchi, Anoop Misra, Nahum Méndez-Sánchez, Nicholas Beng Hui Ng, Claude Marcus, Amanda E. Staiano, Nadia Waheed, Saleh A. Alqahtani, Cosimo Giannini, Ponsiano Ocama, Mindie H. Nguyen, Maria Teresa Arias-Loste

Population and Public Health Science Faculty Publications

Background: Non-alcoholic fatty liver disease (NAFLD) is highly prevalent in children and adolescents, particularly those with obesity. NAFLD is considered a hepatic manifestation of the metabolic syndrome due to its close associations with abdominal obesity, insulin resistance, and atherogenic dyslipidemia. Experts have proposed an alternative terminology, metabolic dysfunction-associated fatty liver disease (MAFLD), to better reflect its pathophysiology. This study aimed to develop consensus statements and recommendations for pediatric MAFLD through collaboration among international experts. Methods: A group of 65 experts from 35 countries and six continents, including pediatricians, hepatologists, and endocrinologists, participated in a consensus development process. The process encompassed …


College Of Nursing And Dietetic Intern Ng Tube Placement Training And Nutrition Assessment/Formula Selection Interprofessional Education Activity - A Student Perspective, Kimberly Jaramillo, Josephine Titus, Amanda Dunn, Diana Gonzales-Pacheco Jul 2024

College Of Nursing And Dietetic Intern Ng Tube Placement Training And Nutrition Assessment/Formula Selection Interprofessional Education Activity - A Student Perspective, Kimberly Jaramillo, Josephine Titus, Amanda Dunn, Diana Gonzales-Pacheco

InterProfessional Education Research and Scholarship

Introduction

University of New Mexico College of Nursing (CON) students and College of Education and Health Sciences (COEHS) dietetic interns (DI) participated in an IPE activity to fulfill the Dietetic Internship (DI) competency for (NG) tube placement and CON clinical objectives.

Methods

Fourteen pre-licensure BSN students and seven DI graduate students participated in the IPE activity. CON students presented nursing roles during NG tube placement and answered questions regarding clinical experiences. In small groups, nursing students demonstrated NG tube placement procedures using simulation mannequins, which the dietetic interns then practiced.

The dietetic interns presented the role of registered dietitian nutritionists. …


Interprofessional Activities Of The Clinical Dietetics Club Of Unm: Presentations On Disease And Cooking For Therapy, Arlin Diaz Torres, Jenelle Audrienne Torres, Sergei Smishko, Izabelle Chavez, Diana Gonzales-Pacheco Jul 2024

Interprofessional Activities Of The Clinical Dietetics Club Of Unm: Presentations On Disease And Cooking For Therapy, Arlin Diaz Torres, Jenelle Audrienne Torres, Sergei Smishko, Izabelle Chavez, Diana Gonzales-Pacheco

InterProfessional Education Research and Scholarship

The Clinical Dietetics Club of UNM (CDCU) is a student-run organization that offers interprofessional educational activities to help close the gap in nutrition education, often lacking in medical professional training. The CDCU organized two educational presentations led by UNM faculty dietitians on critical topics, including cardiovascular disease (CVD), celiac disease, gout, and non-alcoholic fatty liver disease (NAFLD). These sessions had between 13 - 21 participants and offered informational credit. The sessions also received positive feedback, with 80% of participants in the CVD and Celiac Disease presentation and 87% in the Gout and NAFLD presentation rating the sessions as or higher …


Annual Ipe Day 2024 Conference Package, Health Sciences Office Of Interprofessional Education Jul 2024

Annual Ipe Day 2024 Conference Package, Health Sciences Office Of Interprofessional Education

InterProfessional Education Research and Scholarship

No abstract provided.


Critical Geospatial Data Science: Principles For Curating, Analyzing, And Sharing Geospatial Data, Daniel Beene Jul 2024

Critical Geospatial Data Science: Principles For Curating, Analyzing, And Sharing Geospatial Data, Daniel Beene

Geography ETDs

Critical geospatial data science (CGDS) offers principles for engaging with geospatial data, methods, and translation by pulling from critical epistemologies in geography. CGDS interrogates objective “truths” in science by actively engaging in critique of geospatial data and methodologies. Specifically, CGDS contends with the political context and motivations behind geospatial data science (GDS) while using GDS methods to understand how social-spatial arrangements manifest and are reinforced through data. CGDS explicitly aims to inform practices for criticality from within GDS and provides opportunities for multidisciplinary research that incorporates social theories, contextualizes geospatial data, and critically evaluates the effects and ethics of (under)representation …


Otocolobus Manul (Carnivora: Felidae), Paula Noonan, Zoe Baker, Virginia Hayssen Jul 2024

Otocolobus Manul (Carnivora: Felidae), Paula Noonan, Zoe Baker, Virginia Hayssen

Biological Sciences: Faculty Publications

Otocolobus manul (Pallas, 1776) is a small, solitary, terrestrial felid commonly called the Manul and is the sole species of its genus. It occurs in Afghanistan, Armenia, Bhutan, China, India, the Islamic Republic of Iran, Kazakhstan, Kyrgyzstan, Mongolia, Nepal, Pakistan, the Russian Federation, and Turkmenistan. Otocolobus manul might still occur in Tajikistan and Uzbekistan but might be extinct in Azerbaijan. As assessed in 2020, O. manul is listed as “Least Concern” (LC) on the International Union for Conservation of Nature and Natural Resources Red List of Threatened Species, with an estimate of 58,000 adults, although the population might be decreasing.


Describing Nursing Care Of Severely Obese Patients In Critical Access Hospitals Using Total Quality Management Theory: A Qualitative Study, Amy M. Blankenship Jul 2024

Describing Nursing Care Of Severely Obese Patients In Critical Access Hospitals Using Total Quality Management Theory: A Qualitative Study, Amy M. Blankenship

Dissertations

The purpose of this study was to explore nurses' perceptions and experiences regarding caring for severely obese patients and factors that affect quality care of these patients in Critical Access Hospitals (CAHS).


East African Refugee Women Seeking Health Care After Government Assistance Ends, Sylivia Chelimo Jul 2024

East African Refugee Women Seeking Health Care After Government Assistance Ends, Sylivia Chelimo

Walden Dissertations and Doctoral Studies

East African refugee women arrive as a vulnerable population in their host country. Before coming to the United States, refugee women may have experienced varying levels of trauma due to civil wars, genocide, sexual assault, deaths of loved ones, terrorist attacks, being taken hostage, and torture in their home country. The purpose of this generic qualitative study was to explore the experiences of refugee women from East African countries seeking health care in the Central United States when government assistance ends. The framework of the behavioral model of health was the guide for examining the experiences of the participant refugee …


Essays On Health, Labor, And Development Economics, Md Mohsan Khudri Jul 2024

Essays On Health, Labor, And Development Economics, Md Mohsan Khudri

Electronic Theses and Dissertations Archive

In the first essay, using data from the Panel Study of Income Dynamics, I estimate the impact of breastfeeding initiation and duration on multiple cognitive, health, and behavioral outcomes spanning early childhood through adolescence. To mitigate the potential bias, I employ a doubly robust (DR) estimation method, addressing misspecification in either the treatment or outcome models while adjusting for selection effects. My novel approach is to use and evaluate a battery of supervised machine learning (ML) algorithms to improve propensity score (PS) estimates. I demonstrate that the gradient boosting machine algorithm removes bias more effectively and minimizes other prediction errors …


27-Hydroxycholesterol Acts On Estrogen Receptor Α Expressed By Pomc Neurons In The Arcuate Nucleus To Modulate Feeding Behavior, Hui Ye, Xiaohua Yang, Bing Feng, Pei Luo, Valeria C Torres Irizarry, Leslie Carrillo-Sáenz, Meng Yu, Yongjie Yang, Benjamin P Eappen, Marcos David Munoz, Nirali Patel, Sarah Schaul, Lucas Ibrahimi, Penghua Lai, Xinyue Qi, Yuliang Zhou, Maya Kota, Devin Dixit, Madeline Mun, Chong Wee Liew, Yuwei Jiang, Chunmei Wang, Yanlin He, Pingwen Xu Jul 2024

27-Hydroxycholesterol Acts On Estrogen Receptor Α Expressed By Pomc Neurons In The Arcuate Nucleus To Modulate Feeding Behavior, Hui Ye, Xiaohua Yang, Bing Feng, Pei Luo, Valeria C Torres Irizarry, Leslie Carrillo-Sáenz, Meng Yu, Yongjie Yang, Benjamin P Eappen, Marcos David Munoz, Nirali Patel, Sarah Schaul, Lucas Ibrahimi, Penghua Lai, Xinyue Qi, Yuliang Zhou, Maya Kota, Devin Dixit, Madeline Mun, Chong Wee Liew, Yuwei Jiang, Chunmei Wang, Yanlin He, Pingwen Xu

Faculty, Staff and Students Publications

Oxysterols are metabolites of cholesterol that regulate cholesterol homeostasis. Among these, the most abundant oxysterol is 27-hydroxycholesterol (27HC), which can cross the blood-brain barrier. Because 27HC functions as an endogenous selective estrogen receptor modulator, we hypothesize that 27HC binds to the estrogen receptor α (ERα) in the brain to regulate energy balance. Supporting this view, we found that delivering 27HC to the brain reduced food intake and activated proopiomelanocortin (POMC) neurons in the arcuate nucleus of the hypothalamus (POMCARH) in an ERα-dependent manner. In addition, we observed that inhibiting brain ERα, deleting ERα in POMC neurons, or chemogenetic inhibition of …


The Level Of Mental Health Among Abused Syrian Female Refugees According To Some Variables, Doaa Barakat, Fawwaz Al-Momani Jul 2024

The Level Of Mental Health Among Abused Syrian Female Refugees According To Some Variables, Doaa Barakat, Fawwaz Al-Momani

Jordan Journal of Applied Science-Humanities Series

This study aimed to explore the level of psychological health domains among abused Syrian refugees. To achieve the study's objectives, a descriptive survey method was used, and the mental health scale was administered. The study sample consisted of 300 abused female Syrian refugees. The validity and reliability of the scale were verified. The findings revealed that the levels of depression and anxiety domains on the mental health scale were high among the abused female Syrian refugees, while the means of the positive influence and behavior control domains were at an average level. Additionally, there were no statistically significant differences between …


Inter-Kingdom Communication And The Sympoietic Way Of Life, Scott F. Gilbert Jul 2024

Inter-Kingdom Communication And The Sympoietic Way Of Life, Scott F. Gilbert

Biology Faculty Works

Organisms are now seen as holobionts, consortia of several species that interact metabolically such that they sustain and scaffold each other’s existence and propagation. Sympoiesis, the development of the symbiotic relationships that form holobionts, is critical for our understanding the origins and maintenance of biodiversity. Rather than being the read-out of a single genome, development has been found to be sympoietic, based on multigenomic interactions between zygote-derived cells and symbiotic microbes. These symbiotic and sympoietic interactions are predicated on the ability of cells from different kingdoms of life (e.g., bacteria and animals) to communicate with one another and to have …


Issue 447: July 11-25, 2025, The Local Voice Jul 2024

Issue 447: July 11-25, 2025, The Local Voice

The Local Voice

No abstract provided.


Wiping Out Central Line Associated-Bloodstream Infections: Cleaning High Touch Surfaces In The Picu, Emily Heth Jul 2024

Wiping Out Central Line Associated-Bloodstream Infections: Cleaning High Touch Surfaces In The Picu, Emily Heth

Dissertations

Problem: Central line-associated bloodstream infections (CLABSIs) are a significant, preventable healthcare-related complication of hospital admission and medical management of critically ill and medically complex patients. CLABSIs result in significant adverse outcomes such as increased morbidity and mortality, prolonged length of stay (LOS) in the intensive care unit (ICU) and in the hospital, increased cost of treatment, and increased rates of readmission. Direct and indirect contact within the patient’s hospital environment are potential means of transmission for microorganisms, increasing the inherent risk of acquiring a CLABSI.

Method: For this quality improvement (QI) project, a pre-post design was utilized to evaluate the …


Histopathology Imaging And Clinical Data Including Remission Status In Pediatric Inflammatory Bowel Disease, Chloe Martin-King, Ali Nael, Louis Ehwerhemuepha, Blake Calvo, Quinn Gates, Jamie Janchoi, Elisa Ornelas, Melissa Perez, Andrea Venderby, John Miklavcic, Peter Chang, Aaron Sassoon, Kenneth Grant Jul 2024

Histopathology Imaging And Clinical Data Including Remission Status In Pediatric Inflammatory Bowel Disease, Chloe Martin-King, Ali Nael, Louis Ehwerhemuepha, Blake Calvo, Quinn Gates, Jamie Janchoi, Elisa Ornelas, Melissa Perez, Andrea Venderby, John Miklavcic, Peter Chang, Aaron Sassoon, Kenneth Grant

Food Science Faculty Articles and Research

The incidence of inflammatory bowel disease (IBD) is increasing annually. Children with IBD often suffer significant morbidity due to physical and emotional effects of the disease and treatment. Corticosteroids, often a component of therapy, carry undesirable side effects with long term use. Steroid-free remission has become a standard for care-quality improvement. Anticipating therapeutic outcomes is difficult, with treatments often leveraged in a trial-and-error fashion. Artificial intelligence (AI) has demonstrated success in medical imaging classification tasks. Predicting patients who will attain remission will help inform treatment decisions. The provided dataset comprises 951 tissue section scans (167 whole-slides) obtained from 18 pediatric …


Improved Whole-Mount Immunofluorescence Protocol For Consistent And Robust Labeling Of Adult Drosophilamelanogaster Adipose Tissue, Rachael K. Ott, Isaiah H. Williams, Alissa R. Armstrong Jul 2024

Improved Whole-Mount Immunofluorescence Protocol For Consistent And Robust Labeling Of Adult Drosophilamelanogaster Adipose Tissue, Rachael K. Ott, Isaiah H. Williams, Alissa R. Armstrong

Faculty Publications

Energy storage and endocrine functions of the Drosophila fat body make it an excellent model for elucidating mechanisms that underlie physiological and pathophysiological organismal metabolism. Combined with Drosophila's robust genetic and immunofluorescence microscopy toolkits, studies of Drosophila fat body function are ripe for cell biological analysis. Unlike the larval fat body, which is easily removed as a single, cohesive sheet of tissue, isolating intact adult fat body proves to be more challenging, thus hindering consistent immunofluorescence labeling even within a single piece of adipose tissue. Here, we describe an improved approach to handling Drosophila abdomens that ensures full access of …


Challenges Of Spatially Resolved Metabolism In Cancer Research, Andrew N. Lane, Richard M. Higashi, Teresa W-M Fan Jul 2024

Challenges Of Spatially Resolved Metabolism In Cancer Research, Andrew N. Lane, Richard M. Higashi, Teresa W-M Fan

Markey Cancer Center Faculty Publications

Stable isotope-resolved metabolomics comprises a critical set of technologies that can be applied to a wide variety of systems, from isolated cells to whole organisms, to define metabolic pathway usage and responses to perturbations such as drugs or mutations, as well as providing the basis for flux analysis. As the diversity of stable isotope-enriched compounds is very high, and with newer approaches to multiplexing, the coverage of metabolism is now very extensive. However, as the complexity of the model increases, including more kinds of interacting cell types and interorgan communication, the analytical complexity also increases. Further, as studies move further …


The Interplay Of Corporate Social Responsibility (Csr), Employees In The Convenience Store Sector, And Net Promoter Score (Nps) Impact, Musa Pinar, Faruk Guder, Tulay Girard Jul 2024

The Interplay Of Corporate Social Responsibility (Csr), Employees In The Convenience Store Sector, And Net Promoter Score (Nps) Impact, Musa Pinar, Faruk Guder, Tulay Girard

The Journal of Values-Based Leadership

In the realm of a convenience store business, this study aims to examine: 1) customer perceptions of CSR activities, employee behavior, and value congruity; 2) the potential impact of respondent demographics on CSR activities, employee behavior, value congruity, and the likelihood of recommending convenience stores and fuel businesses; 3) the relationships between CSR activities, employee behavior, and value congruity, and 4) the impact of CSR activities and gender on the likelihood of customer recommendation of the brand. Based on 2000 surveys from the loyalty members, the study found that CSR activities, employee behaviors, and value congruity are important for business …


Detection And Quantification Of Acetaminophen In Aquatic Samples From Cádiz, Spain, Hannah R. Desmarais, Michelle N. Mikos Jul 2024

Detection And Quantification Of Acetaminophen In Aquatic Samples From Cádiz, Spain, Hannah R. Desmarais, Michelle N. Mikos

DePaul Discoveries

Pharmaceutical contaminants in water are becoming increasingly prevalent. This could have potentially harmful effects on human health and aquatic environments, even at low concentrations. Acetaminophen, the active ingredient of Tylenol ®, was the target compound for this study, and the aim was to determine is presence and concentration in various aquatic samples in and around the city of Cádiz, Spain. It was predicted that acetaminophen would be detected in low concentrations in river water, drain outflow, University of Cádiz saltwater flow, and lagoon water, but undetectable in the University of Cádiz sink water and fountain water. The presence and concentration …


Framing The Path To Fitness: Age Differences In Response To Framed Exercise Messages, Iliya Sherif, David B. Taullahu, Alyssa R. Minton, Joseph A. Mikels Jul 2024

Framing The Path To Fitness: Age Differences In Response To Framed Exercise Messages, Iliya Sherif, David B. Taullahu, Alyssa R. Minton, Joseph A. Mikels

DePaul Discoveries

Physical activity is one of the most protective health behaviors one can engage in, yet 75% of active adults in the US, meaning those who exercise regularly, fall short of the recommended levels of physical activity, with an even greater percentage of older adults living inactive lives, meaning they exercise minimally and engage in prolonged sedentary behavior (CDC, 2019). The goal of the current study was to explore different types of message framing targeted at encouraging older and younger adults to exercise. We recruited older adults (n = 184; Mage = 69.45 years, age range: 65- 80 years) and younger …