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Clemson University Board Of Trustees, Full Minutes, 2024 July 18, Clemson University Board Of Trustees

Minutes

No abstract provided.

Optimizing Adherence To Antiretroviral Therapy Among Adolescents Living With Hiv In Low And Middle-Income Settings, Samuel Kizito

Brown School Graduate Student Theses and Dissertations

Globally, 1.8 million adolescents are living with HIV (ALHIV), of whom 89% (1.5 million) are in Sub-Saharan Africa (SSA) (UNAIDS, 2021b). Unfortunately, despite advances in prevention—such as the prevention of mother to child transmission (PMTCT) and pre-exposure prophylaxis—new infections continue to occur. For example, in 2021 alone, the number of new HIV infections among adolescents aged 10 to 19 was 160,000 cases. Moreover, the rate of HIV-related deaths among adolescents has only declined by 10% in the last decade, which is not fast enough to meet the 2030 global targets. Despite antiretroviral therapy (ART) playing a crucial role in controlling …

Clemson University Board Of Trustees, Finance And Facilities Committee, 2024 July 18, Clemson University Board Of Trustees

Minutes

No abstract provided.

Membrane Vectorial Lipidomic Features Of Coral Host Cells’ Plasma Membrane And Lipid Profiles Of Their Endosymbionts Cladocopium, Tatyana V Sikorskaya, Ekaterina V Ermolenko, Taliya T Ginanova, Andrey V Boroda, Kseniya V Efimova, Mikhail Bogdanov

Faculty, Staff and Student Publications

The symbiotic relationships between coral animal host and autotrophic dinoflagellates are based on the mutual exchange and tight control of nutritional inputs supporting successful growth. The corals Sinularia heterospiculata and Acropora aspera were cultivated using a flow-through circulation system supplying seawater during cold and warm seasons of the year, then sorted into host cells and symbionts and subjected to phylogenetic, morphological, and advanced lipid analyses. Here we show, that the lipidomes of the dinoflagellates Cladocopium C1/C3 and acroporide-specific Cladocopium hosted by the corals, are determined by lipidomic features of different thermosensitivity and unique betaine- and phospholipid molecular species. Phosphatidylserines and …

Indigenous Practices In Head Start Classrooms— Toward Survivance And Indigenization In Policy And Practice, Liza Xet Smith

LMU Theses and Dissertations

The Office of Head Start has prioritized holistic quality education services for children and communities in greatest need. First, since 1965, the federal government has funded, regulated, and publicly aided over 38 million children through Head Start programming, including AIAN and Migrant programs (Administration for Children and Families, n.d.). In 2019, over $10 billion was budgeted for the program, resulting in 1,047,000 low-income children and their families receiving services (Office of Head Start, 2022a). In addition, the Office of Planning, Research, and Evaluation has funded research to improve quality and child outcomes, with research recommendations that significantly guide state and …

Finding The Gut Microbiome Connection To The Risk Of Childhood Obesity Through An Examination Of Gut Microbiota Among Children In Los Angeles, California: A Cross-Sectional Pilot Study, Cecille M. Basilio

Dissertations

The purpose of this study was to examine the association between gut microbiota composition and child obesity. The specific aims were to: 1) evaluate the impact of child obesity status on three related outcomes to be assessed by extracting DNA from children's stool samples using 16S rRNA gene sequencing: alpha diversity of gut microbiota composition, Firmicutes: Bacteroidetes ratio, and abundance of SCFA-generating gut microbes between obese and non-obese school children; 2) compare the dietary habits and intakes between obese and non-obese school children; and 3) evaluate the association of body mass index differences in gut microbiota composition between obese and …

Microrna166: Old Players And New Insights Into Crop Agronomic Traits Improvement, Zhanhui Zhang, Tianxiao Yang, Na Li, Guiliang Tang, Jihua Tang

Michigan Tech Publications

MicroRNA (miRNA), a type of non-coding RNA, is crucial for controlling gene expression. Among the various miRNA families, miR166 stands out as a highly conserved group found in both model and crop plants. It plays a key role in regulating a wide range of developmental and environmental responses. In this review, we explore the diverse sequences of in major crops and discuss the important regulatory functions of miR166 in plant growth and stress responses. Additionally, we summarize how miR166 interacts with other miRNAs and highlight the potential for enhancing agronomic traits by manipulating the expression of miR166 and its targeted …

The Association Of Vitamin D Levels And Dental Caries In Older Adults: A Cross-Sectional Study., Man Hung, Amir Mohajeri, Mahsa Sadri, Elahe Khodabandeh, Ibrahim Zeitoun, Martin S. Lipsky

Institute on Aging Publications

Most research examining vitamin D and dental caries focuses on children and younger adults. This study investigated the association between vitamin D levels and dental caries in older adults using data from the United States National Health and Nutrition Examination Survey from 2011 to 2016.

The Evaluation Of Quality Engineering For Supply Chain Operations In Khan Dhari Silo / Case Study, Muhammad Hardan Sultan, Batool Attia Khalaf

Journal of Economics and Administrative Sciences

The study aims to search for mechanisms to improve the supply chain operations in the silo of Khan Dhari by applying the requirements of quality engineering and focusing on the axes of design, human engineering and value engineering, which are among the most important axes concerned with quality engineering in the silo. The case study approach was relied upon as an approach that helps in the comprehensive and in-depth analysis of the research problem, and the researcher relied on checklists in collecting and analyzing data. The research problem is summarized in the main question (there are failures and stops in …

Vitamin D Deficiency, Hypertension, And Cardiovascular Diseases In Post-Menopausal African American Women: The Jackson Heart Study, Michelle Alexander

Electronic Theses and Dissertations Archive

Cardiovascular disease is a primary health burden in the population that affects all ethnic groups. Hypertension is also a condition that is very prevalent in the population and is a major risk factor for cardiovascular disease is hypertension. African Americans have the highest prevalence of hypertension and cardiovascular disease as well as higher mortality rates compared to other ethnicities. Vitamin D deficiency affects all populations and research has shown it to be a risk factor for both hypertension and cardiovascular diseases. In this study we examined the association between vitamin D deficiency and cardiovascular diseases, and the association vitamin D …

A Randomized Controlled Trial Testing The Effects Of A Social Needs Navigation Intervention On Health Outcomes And Healthcare Utilization Among Medicaid Members With Type 2 Diabetes, Amy Mcqueen, David Von Nordheim, Charlene Caburnay, Linda Li, Cynthia Herrick, Lauren Grimes, Darrell Broussard, Rachel E Smith, Dana Lawson, Yan Yan, Matthew Kreuter

2020-Current year OA Pubs

Health systems are increasingly assessing and addressing social needs with referrals to community resources. The objective of this randomized controlled trial was to randomize adult Medicaid members with type 2 diabetes to receive usual care (

Organizational Capacity And Women’S Empowerment: A Case Study Of Women Farmers’ Groups In Sustainable Food Garden Programs In Indonesia, Sulikah Asmorowati, Medy Kresno Dwipoyono, Nadia Sukmawati, Feny Dwintania, Nor Hafizah Hj Mohamed Harith, Eko Supeno, Gitadi Tegas Supramudyo

Journal of International Women's Studies

Efforts for empowering women have been a priority agenda in development because women make crucial contributions to society. One of the significant issues that women are well positioned to address is the stunting or impaired development of children due to poor nutrition. As this issue is a threat for national development in Indonesia, the central government has initiatives to tackle stunting, and one of these is the Sustainable Food Garden, or Pekarangan Pangan Lestari (P2L). The innovative program is designed to prevent stunting by empowering women, which also contributes to the attainment of Sustainable Development Goals (SDGs). This research is …

Cost Effectiveness Analysis Of The Community And Hospital Based Management Of Acute Malnutrition: A Case From Jharkhand, India, Rajesh Kumar Sinha

Management Dynamics

Background: Severe Acute Malnutrition (SAM) among children remains unacceptably high in Jharkhand. A Community-based Management of SAM (CMAM) intervention, which provides full continuum of care provided by the CMAM intervention, from inpatient treatment for medically complicated SAM cases to outpatient treatment for uncomplicated SAM cases, was conducted to treat children with SAM by the government appointed community health workers.

Methods: Costs of treating a case of uncomplicated SAM in the CMAM intervention were estimated from the provider’s and societal perspectives, in the research setting and from the provider’s perspective in the government setting. Costs of the In-patient/Facility-based Management of SAM …

Perceived Effects Of Climate Change On Aquaculture Production In Zambia: Status, Vulnerability Factors, And Adaptation Strategies, Sahya Maulu, Oliver J. Hasimuna, Moses Chibesa, Ian Bbole, Joseph Mphande, Mazuba Mwanachingwala, Kundananji Nawanzi, Doubt Chibeya, Sillah Siavwapa, Joyce Mbewe, Lucy Namukonda, Friday Balungu, Inyambo Mumbula, Mwangala Kabika, Shimbetu Mweemba, Mwaanda Sikanyenyene, Enock Siankwilimba, Imikendu Imbwae, Hansel M. Mweetwa

School of Biological and Marine Sciences

Aquaculture plays a critical role in Zambia's food and nutrition security. However, aquaculture is highly vulnerable to the effects of a changing climate which can lead to economic losses, and food and nutrition insecurity. In this study, we investigated the perceived effects of climate change on aquaculture production in Zambia, vulnerability factors, and adaptation strategies. We used semi-structured and structured questionnaires to collect data from aquaculture producers in all provinces across the country. Results revealed high (over 80%) awareness of climate change, primarily attributed to literacy levels and access to media. Producers perceived occurrence of climate-related changes such as rising …

Understanding The Roles Of Economy And Society In The Relative Risks Of Zoonosis Emergence From Livestock, Stephen Hinchcliffe, Alex Blanchette, Kin Wang (Ray) Chan, Chris Degeling, Jody Emel, Melissa Leach, Ian Scoones, Michael Winter

Geography

The emergence of zoonotic infections that can develop into pathogens of pandemic potential is a major concern for public health. The risks of emergence and transmission relate to multiple factors that range from land use to human-non-human animal contacts. Livestock agriculture plays a potentially significant role in those risks, shaping landscapes and providing hosts that can act as the source or amplifiers of emergent pathogens. The relative risks will be contingent upon the nature of those systems, with comparisons often made between intensive, indoor, biosecure systems and more extensive, outdoor, insecure systems. Microbiological, ecological and veterinary sciences provide useful entry …

Sea Anemones (Actinia Equina) Show Consistent Individual Differences In Boldness And Thoroughness But Lack A Behavioural Syndrome, Samantha Simpson, Mark Briffa

School of Biological and Marine Sciences

Behavioural syndromes are suites of behaviours that corelate between-individuals but the same behaviours may also show within-individual correlations owing to state dependency or trade-offs. Therefore, overall phenotypic behavioural correlations must be separated into their between- and within-individual components. We investigate how startle response duration (an index of boldness) and time taken to reject an inert item (an index of investigation thoroughness) covary in beadlet sea anemones, Actinia equina. Anemones took longer to reject a more complex item compared to a simpler one, validating this measure of investigation thoroughness. We then quantified between- and within-individual correlations using a Bayesian analysis and …

Dietary Tea Polyphenol Supplementation And Its Impacts On Growth Performance, Plasma Parameters, And Antioxidant Capacity Of Juvenile Genetically Improved Farmed Tilapia (Gift: Oreochromis Niloticus), Christopher Peterson Daniel, Sahya Maulu, Wenqiang Jiang, Shiyou Chen, Linghong Miao, Xiangping Ge

School of Biological and Marine Sciences

The term ‘tea polyphenols’ (TPs) comprises a broad range of polyphenol compounds present in tea, demonstrating positive health effects such as antioxidant activity, etc. in animals. This study investigated the effects of TPs supplementation in juvenile genetically improved farmed tilapia (GIFT); Oreochromis niloticus). Fifteen fish (weight: 13.46 ± 1.25 g) were distributed in six tanks and randomly assigned with diets containing graded levels of TPs (mg/kg): 0.00 (control), 100, 200, 300, 400 and 500 in quadruplicate for 8 weeks. After the trial, the fish fed 500 mg/kg TPs exhibited a significant reduction (p < 0.05) in final body weight (FBW) compared with the control. Whole-body moisture content was elevated, while crude protein was lowered significantly (p < 0.05) by a 100 mg/kg TPs diet compared with the control. Plasma low-density lipoprotein (LDL) was significantly elevated (p < 0.05) at over 200 mg/kg; triglyceride (TG) content was lowered (p < 0.05) by the TPs diet compared with the control diet. Catalase (CAT) was significantly enhanced (p < 0.05) by TPs except at 300 mg/kg; superoxide dismutase (SOD) was increased (p < 0.05) by 200, 400 and 500 mg/kg; total antioxidant capacity (T-AOC) was enhanced (p < 0.05) by 400–500 mg/kg; glutathione (GSH) was improved (p < 0.05) by 500 mg/kg; and malondialdehyde (MDA) level was elevated (p < 0.05) in the 100–200 mg/kg TPs diet compared with the control. TPs can be utilized as a feed supplement to improve the plasma biochemical parameters and AOC of GIFT juveniles.

Predation Of Appendicularians On Prochlorococcus, Carey Sweeney

Dissertations and Theses

Prochlorococcus is the most abundant photosynthetic cell on Earth. This picocyanobacterium is critical to primary productivity and biogeochemical cycles of the open ocean. While abiotic environmental factors that influence Prochlorococcus are relatively well-understood, biotic controls are less well known. Appendicularians are ubiquitous gelatinous zooplankton that feed on marine microorganisms including Prochlorococcus. However, the details of this feeding interaction are extremely understudied relative to its potential importance. In this study, I characterized the relationship between appendicularians and Prochlorococcus with laboratory experiments. I showed that feeding on Prochlorococcus changes with the life stage of the appendicularians and concentration of prey. I …

Library Services And Resource Provision To Prison Inmates In Enugu Maximum Prison Library, Enugu State, Nigeria, Andrew Ifeanyi Ifeabor, Godwin Sunday Ezeh, Comfort Ometere Alabi, Margaret N. Ngwuchukwu

Library Philosophy and Practice (e-journal)

The study focused on library services and resource provision to prison inmates in Enugu Maximum Prison Library Enugu State Nigeria. Four (4) research questions were formulated to guide the study. The objectives of the study were to find out the extent of library services provision to the prison inmates, extent of provision of library resources to the inmates, agencies that provide resources and services to the Prison Library, and the problems associated with the provision of library services and resources to meet the inmates’ information needs. Eighty-three (83) respondents comprising eighty prison inmates and three library staff were used as …

Recognizing 30 Years Of Accomplishments And Envisioning An Innovative Future - The 2024 Annual Conference Of The Health Care Systems Research Network, Michael A. Horberg, Suzanne Simons, Robert T. Greenlee

Journal of Patient-Centered Research and Reviews

The Health Care Systems Research Network (HCSRN) kicked off the 2024 Annual Conference on April 9, 2024, in Milwaukee at the Hyatt Regency with nearly 275 participants from 19 HCSRN member institutions. This year, HCSRN attendees joined their colleagues to reconnect and network during the three-day conference featuring the theme, “Advancing High-Quality, Equitable Research in the Age of New Health Care Technologies.”

Health-Promoting Behavior As A Predictor Of Bachelor Of Science In Nursing Faculty Intent To Remain In Academe, Felisa Haywood Smith

Dissertations

The purpose of this predictive study was to identify whether health-promoting behavior, as identified in the Health-Promoting Lifestyle Profile II (HPLP II), is a significant predictor for intent to remain in academe teaching in Bachelor of Science in Nursing (BSN) programs among nursing faculty at four-year institutions in the Southern region of the United States. Health-promoting behavior dimensions measured by the HPLP II are physical activity, health responsibility, nutrition, interpersonal relations, spiritual growth, and stress management.

Factors Associated With Increased Health Care Utilization For Patients With Dementia With Lewy Bodies: A Narrative Review, Kathryn A. Wyman-Chick, Matthew J. Barrett, Michael J. Miller, Jennifer L. Kuntz, Ella A. Chrenka, Rebecca C. Rossom

Journal of Patient-Centered Research and Reviews

Numerous studies have demonstrated that dementia is associated with increased utilization of health care services, which in turn results in increased costs of care. Dementia with Lewy bodies (DLB) is associated with greater costs of care relative to other forms of dementia due to higher rates of hospitalization and nursing home placement directly related to neuropsychiatric symptoms, parkinsonism, increased susceptibility to delirium, and elevated rates of caregiver burden. There is a critical need for researchers to identify potentially modifiable factors contributing to increased costs of care and poor clinical outcomes for patients with DLB, which may include comorbidities, polypharmacy/contraindicated medications, …

Effect Of Resistance Training On Physical Function During Chemotherapy In Colon Cancer, Justin C. Brown, Shengping Yang, Stephanie L.E. Compton, Kristin L. Campbell, Elizabeth M. Cespedes Feliciano, Sara Quinney, Barbara Sternfeld, Bette J. Caan, Jeffrey A. Meyerhardt, Kathryn H. Schmitz

School of Medicine Faculty Publications

Background: The decline of physical function during chemotherapy predicts poor quality of life and premature death. It is unknown if resistance training prevents physical function decline during chemotherapy in colon cancer survivors. Methods: This multicenter trial randomly assigned 181 colon cancer survivors receiving postoperative chemotherapy to home-based resistance training or usual care control. Physical function outcomes included the short physical performance battery, isometric handgrip strength, and the physical function subscale of the Medical Outcomes Short-Form 36-item questionnaire. Mixed models for repeated measures quantified estimated treatment differences. Results: At baseline, participants had a mean (SD) age of 55.2 (12.8) years; 67 …

Allopurinol: Clinical Considerations In The Development And Treatment Of Stevens-Johnson Syndrome, Toxic Epidermal Necrolysis, And Other Associated Drug Reactions, Kathryn M. Dillman, Alison M. Hawkins, Amanda R. Ragland, Grace C. Wester, Driskell R. Greene, Giustino Varrassi, Peyton Moore, Raju Behara, Shahab Ahmadzadeh, Harish Siddaiah, Sahar Shekoohi, Alan D. Kaye

School of Medicine Faculty Publications

Allopurinol lowers urate production through the inhibition of xanthine oxidase. It is oxidatively hydroxylated to oxypurinol and is the most prescribed medication for gout treatment. Although it has a beneficial effect in the treatment of this common disease, like many medications, it is also known for having numerous adverse effects. Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN), diseases that exist on a spectrum, are two of the most dangerous adverse effects associated with allopurinol use. These immune-mediated disease processes involve almost every organ system. They are essential to recognize as early as possible, as they could potentially be deadly, …

Dietary Acculturation Is Associated With Altered Gut Microbiome, Circulating Metabolites, And Cardiovascular Disease Risk In Us Hispanics And Latinos: Results From Hchs/Sol, Yi Wang, Guo-Chong Chen, Zheng Wang, Kai Luo, Yanbo Zhang, Yang Li, Amanda C Mcclain, Marta M Jankowska, Krista M Perreira, Josiemer Mattei, Carmen R Isasi, Maria M Llabre, Bharat Thyagarajan, Martha L Daviglus, Linda Van Horn, David Goldsztajn Farelo, Luis E Maldonado, Steven R Levine, Bing Yu, Eric Boerwinkle, Rob Knight, Robert D Burk, Robert C Kaplan, Qibin Qi, Brandilyn A Peters

Faculty, Staff and Student Publications

Background: Dietary acculturation, or adoption of dominant culture diet by migrant groups, influences human health. We aimed to examine dietary acculturation and its relationships with cardiovascular disease (CVD), gut microbiota, and blood metabolites among US Hispanic and Latino adults.

Methods: In the HCHS/SOL (Hispanic Community Health Study/Study of Latinos), US exposure was defined by years in the United States (50 states and Washington, DC) and US nativity. A dietary acculturation pattern was derived from 14 172 participants with two 24-hour dietary recalls at baseline (2008-2011) using least absolute shrinkage and selection operator regression, with food groups as predictors of US …

Association Between Psychological Distress And Diabetic Retinopathy Among U.S. Adults, Claret Ijeoma Onukogu

Walden Dissertations and Doctoral Studies

Diabetes can lead to diabetic retinopathy, an eye disease that causes damaged blood vessels and the growth of abnormal ones, leading to vision loss. The two stages of the disease are non-proliferative and proliferative diabetic retinopathy. In the non-proliferative stage, diabetics develop macular edema and ischemia with shortage of blood in the macula region of the eye, and the vision eventually becomes blurry. However, the proliferative stage is the advanced stage of the disease involves neovascularization and retinal detachment. The quantitative study employed the socioecological model as the theoretical framework to examine the relationship between psychological distress and diabetic retinopathy …

Low Remnant Cholesterol And In-Hospital Bleeding Risk After Ischemic Stroke Or Transient Ischemic Attack, Zhiyuan Wu, Haiping Zhang, Yi Xu, Xia Li, Xingang Li, Lois Balmer, Xiuhua Guo, Qi Zhang, Xiang Han, Lixin Tao

Research outputs 2022 to 2026

BACKGROUND: Bleeding risk brought by intensive lipid-lowering therapy and low low-density lipoprotein cholesterol is concern-ing, while evidence regarding the relationship between remnant cholesterol and bleeding is frightening. This study aimed to investigate the association between remnant cholesterol at admission and an in-hospital bleeding event after acute ischemic stroke or transient ischemic attack (TIA). METHODS AND RESULTS: A total of 3222 eligible patients admitted to Shanghai Huashan Hospital between 2015 and 2021 with complete lipid data were analyzed. Patients were classified into low (<20.0 mg/dL), moderate (20.0–29.9 mg/dL), and high (≥30 mg/dL) groups by remnant cholesterol. The mean age of patients was 63.0± 13.1 years, including 2301 (71.4%) men and 651 (20.2%) with TIA. The median (interquartile range) of remnant cholesterol was 18.6 (13.5–25.9) mg/dL. After adjustment for confounding variables, patients with low remnant cholesterol had a higher risk of bleeding events (odds ratio, 2.56 [95% CI, 1.12–6.67]) than those with moderate remnant cholesterol. The high remnant cholesterol group was not significantly associated with bleeding risk. Combined assessment of low-density lipoprotein cholesterol and remnant cholesterol further identi-fied patients with the highest risk of bleeding events. CONCLUSIONS: Low remnant cholesterol levels were associated with bleeding events during the acute stage of ischemic stroke and TIA. The assessment of remnant cholesterol could inform the bleeding risk during hospitalization both for patients and physicians in clinical practice.

Potential Association Between Arsenic And Vitamin D, Mythri Chittilla, Chantal Uzoma, Desiree Brewer, Mohammed S. Razzaque

School of Medicine Publications

Vitamin D is a pleiotropic hormone that regulates calcium and phosphate homeostasis. The roles of vitamin D can be divided into skeletal and nonskeletal. Its skeletal roles include promoting calcium absorption in the intestines, maintaining adequate levels of calcium and phosphate in the bloodstream, and supporting bone mineralization, thus preventing conditions such as rickets and osteoporosis. Nonskeletal roles encompass a range of functions, including immune system modulation, cardiovascular health, and cell growth regulation. Sufficient concentrations of vitamin D in the bloodstream are 20–100 ng/ml in men, women, and children, but individuals with more pigmented skin, live in environments with less …

Energy Drinks, Shots, And Pre-Workout Supplements: A Brief Review, Jason M. Curtis, Jose Antonio

Journal for Sports Neuroscience

Abstract

Introduction: There are many purported benefits, both physically and mentally, to consuming energy drinks, energy shots, and multi-ingredient pre-workout supplements ¹.

Methods: This current review, we used studies that investigated the benefits of ED, ES, and MIPS products. We looked for studies that reported the effects of these products, both physical and/or mental.

Review Findings: Current literature on these products suggests that the consumption of these ergogenic aids may increase power, force production, anaerobic production, muscular endurance, and endurance performance in athletes as well as improvement in many indices of mental performance ^2,15.

Practical …

Effects Of Two Grazing Conditions On The Reproductive Achievement Of Male Alpaca In The Northern Peru Grasslands, C Pinares, E Malpartida, S Cortez

IGC Proceedings (1977-2023)

Alpaca have recently been introduced to the northern Peru grasslands (Jalca). Effects of two systems of grazing management, co-grazing (with sheep) under fair grassland condition (CGFC) versus exclusive grazing under good grassland condition (EGGC), upon the reproductive achievement was examined from the 6th to the 16th month of age. Each system involved 20 Huacaya animals, managed by individual herders. Availability of herbage preferred by alpaca (HMA) and animal measurements (herbage intake, liveweight, testicle size, penis release from preputial attachments, plasma testosterone) were monitored monthly. Puberty, judged by the penis release from the preputial attachments, was achieved by 7 …