Digital Commons Network^™

The Effect Of The Lunar Cycle On The Demographics Of Asian Elephants Observed In Open Areas In A Protected Wildlife Sanctuary And Surrounding Crop Fields, Serene K. Rivera

Theses and Dissertations

Due to human development and habitat fragmentation, Asian elephants increasingly use human landscapes and encounter people. These interactions have led to negative interactions between humans and elephants, such as crop-raiding. Despite efforts to mitigate these conflicts, farmers have not been able to consistently protect their crops from elephant foraging. Therefore, it is important to understand elephant behavior in these landscapes to help create long term mitigation plans. Specifically, research regarding demographic patterns in Asian elephants’ perceived predation risk can inform wild elephant management. This study used camera traps in Salakpra Wildlife Sanctuary in Kanchanaburi, Thailand to observe the wild Asian …

Optimizing The Protein Yield Of The Collagen Mimetic Peptide: Col108, Fahmida Akter

Theses and Dissertations

Abstract

The fibril-forming collagen mimetic peptide Col108, produced in E. Coli, has shown potential for innovative biomaterial applications. However, further research is constrained by its limited yield. My study aims to enhance the experimental parameters and has successfully pinpointed rifampicin as an efficient method to boost the production of Col108.

Summer Commencement: August 2, 2024, University Of North Dakota

UND Commencement Programs

UND Sumer Commencement program from August 2, 2024.

Lipid Droplet-Associated Hydrolase Mobilizes Stores Of Liver X Receptor Sterol Ligands And Protects Against Atherosclerosis, Young-Hwa Goo, Janeesh Plakkal Ayyappan, Francis D Cheeran, Sushant Bangru, Pradip K Saha, Paula Baar, Sabine Schulz, Todd A Lydic, Bernhard Spengler, Andreas H Wagner, Auinash Kalsotra, Vijay K Yechoor, Antoni Paul

Faculty, Staff and Students Publications

Foam cells in atheroma are engorged with lipid droplets (LDs) that contain esters of regulatory lipids whose metabolism remains poorly understood. LD-associated hydrolase (LDAH) has a lipase structure and high affinity for LDs of foam cells. Using knockout and transgenic mice of both sexes, here we show that LDAH inhibits atherosclerosis development and promotes stable lesion architectures. Broad and targeted lipidomic analyzes of primary macrophages and comparative lipid profiling of atheroma identified a broad impact of LDAH on esterified sterols, including natural liver X receptor (LXR) sterol ligands. Transcriptomic analyzes coupled with rescue experiments show that LDAH modulates the expression …

Znf397 Deficiency Triggers Tet2-Driven Lineage Plasticity And Ar-Targeted Therapy Resistance In Prostate Cancer, Yaru Xu, Yuqiu Yang, Zhaoning Wang, Martin Sjöström, Yuyin Jiang, Yitao Tang, Siyuan Cheng, Su Deng, Choushi Wang, Julisa Gonzalez, Nickolas A Johnson, Xiang Li, Xiaoling Li, Lauren A Metang, Atreyi Mukherji, Quanhui Xu, Carla R Tirado, Garrett Wainwright, Xinzhe Yu, Spencer Barnes, Mia Hofstad, Yu Chen, Hong Zhu, Ariella B Hanker, Ganesh V Raj, Guanghui Zhu, Housheng H He, Zhao Wang, Carlos L Arteaga, Han Liang, Felix Y Feng, Yunguan Wang, Tao Wang, Ping Mu

Faculty, Staff and Students Publications

Cancer cells exhibit phenotypical plasticity and epigenetic reprogramming that allows them to evade lineage-dependent targeted treatments by adopting lineage plasticity. The underlying mechanisms by which cancer cells exploit the epigenetic regulatory machinery to acquire lineage plasticity and therapy resistance remain poorly understood. We identified zinc finger protein 397 (ZNF397) as a bona fide coactivator of the androgen receptor (AR), essential for the transcriptional program governing AR-driven luminal lineage. ZNF397 deficiency facilitates the transition of cancer cell from an AR-driven luminal lineage to a ten-eleven translocation 2 (TET2)-driven lineage plastic state, ultimately promoting resistance to therapies inhibiting AR signaling. Intriguingly, our …

Impact Of Some Parameters On The Survival And Proliferation Of Foodborne Pathogens: Escherichia Coli, Bacillus Subtilis, Staphylococcus Aureus, And Streptococcus Pyogenes, Hassan Agha, Ahmed Bashir Sanaalla, Muhanad Abdullah Salim Abdulsamad, Maroua Abderrahmane Salhi, Ghada Abdu-Razzaq Mohammad, Abdulmutalib Alabeed Alkamil Allaq

AUIQ Complementary Biological System

Food poisoning caused by foodborne microorganisms is a significant public health concern. This study aims to investigate the impact of several nutritional and environmental parameters on the growth of Escherichia coli, Bacillus subtilis, Staphylococcus aureus, and Streptococc pyogenes in both model systems and food. The specific impact of temperature, pH, and UV light stress on pathogens.Applying physical stress on microorganisms is a standard method to induce cell inactivation and promote food stability.This study found that the optimal temperature for the growth of these pathogens is between 30°C and 50°C. No growth was observed beyond 50°C, indicating temperature sensitivity; low temperatures …

Composition Of The Fractions Of Dry, Mature Subterranean Clover Digested In Vivo And In Vitro, L Klein, S K. Baker

IGC Proceedings (1977-2023)

A modified pepsin-cellulase procedure was used to improve the prediction of in vivo digestibility of dry, mature subterranean clovers (Trifolium subterraneum). Feed, faeces, and the residues from this /11 vitro procedure and the i11 vitro procedure of Tilley & Terry were analysed for protein, ash and fibre fractions lo determine the composition of the cell-wall functions that were digested. The extent of digestion of the cell-wall fractions differed between the two in vitro procedures, but the cell-wall fraction that was digested contained similar proportions of cellulose, hemicellulose, protein and lignin. The cellulose and protein contents of the cell-wall digested …

Advancement In In-Silico Drug Discovery From Virtual Screening Molecular Dockings To De-Novo Drug Design Transformer-Based Generative Ai And Reinforcement Learning, Dony Ang

Computational and Data Sciences (PhD) Dissertations

The field of drug discovery has seen remarkable advancements over the past few decades, transitioning from traditional experimental methods to highly sophisticated computational approaches. One of the pivotal techniques in this evolution is virtual screening, which utilizes molecular docking to predict the interaction between small molecules and target proteins. This method has significantly accelerated the initial stages of drug discovery by enabling the high-throughput screening of large chemical libraries. By simulating the binding affinity and stability of potential drug candidates, virtual screening has become a cornerstone in identifying promising compounds for further development.

A notable application of virtual screening was …

Reflecting On, Resetting, And Reimagining Schools In The Post-Pandemic Context: A Case Study In Rural Vermont, Rachel A. Glickman

Dissertation Collection

This qualitative study examines the experiences of public elementary teachers and school leaders to better understand the shifting of educational priorities during the COVID-19 pandemic. Participants share ideas and practices while taking action steps and making recommendations to improve teaching and learning. The research incorporates both case study and action research approaches through a critical inquiry process that centers the voices of those on the front lines of education. This study contributes to the field of Comparative and International Education (CIE) using the original conceptual framework of Institutional Border Theory of Education (IBTE). IBTE draws on pre-existing foundational theories of …

Swallowable Capsules For Precision Probiotics And Future Gut Health Monitoring, Benjamin Terry, John M. Chaston, Scott Weber

BYU Research Development Office Research Networking Conference

Areas of Interest: Gastrointestinal disease and therapy, medical devices, surgical tools

Reducing Musculoskeletal Injury Risk For High School Athletes--A Pilot Project, Matthew K. Seeley

BYU Research Development Office Research Networking Conference

Areas of Interest: Biomechanics, Articular Cartilage Health, Athletic Injury Prevention

Food Choices For Planetary And Personal Health, Jonathan Kershaw

BYU Research Development Office Research Networking Conference

Areas of Interest: Environmental Sustainability, Food Choice, Health and Nutrition

Pediatric Nutrition Screening, Sarah Ballini

BYU Research Development Office Research Networking Conference

Areas of Interest: Pediatric malnutrition, Cystic Fibrosis, Nutrition education

Raman Spectroscopic Applications For Food Safety & Quality, Shintaro Pang

BYU Research Development Office Research Networking Conference

Areas of Interest: Micro- and nano-plastics analysis; Food allergen protein detection and characterization; Rapid detection of lactose and other sugar-related compounds; Probiotics and pathogenic bacteria analysis in complex matrices; Other food, agriculture and environment related analytes of concern

A Decade Of Progress In Sustainability Education And Research: 2014-2024 Impact Report, University Of Dayton. Hanley Sustainability Institute

Hanley Sustainability Institute Documents, Reports and Promotional Materials

• Letter from the Executive Director
• Introduction to the Hanley Sustainability Institute
• Strategic Plan
• Strategic Priorities: Developing Leaders for a Just Future
• Facilitating Impactful Research
• Catalyzing Institutional Transformation
• Engaging Communities Beyond Campus
• Acknowledgments

Pineapple Express: The Legality Of Introducing Cannabis Tourism To Arkansas, Chloe Tyner

Human Nutrition and Hospitality Management Undergraduate Honors Theses

This research delves into the legal aspects of introducing cannabis tourism to Arkansas. The objective of this study was to create a framework for hospitality professionals in Arkansas to understand what areas of recreational cannabis law would impact their industry should Arkansas legalize recreational cannabis. Through a document analysis comparing Arkansas and Colorado’s liquor and cannabis laws, this study investigated how both states regulate alcohol and cannabis and the legal challenges Colorado has seen since its inception of recreational cannabis sales.

Challenges to this study included a limited existing body of knowledge for cannabis tourism and the contradicting federal and …

Exploring The Use Of Withania Somnifera (Ashwagandha) In Treating Generalized Anxiety Disorder: A Systematic Review, Samuel Packham, Heather Justice, Travis Adelman

Doctor of Medical Science (DMSc)

Generalized anxiety disorder (GAD) is a common disorder affecting approximately 4% to 7% of US adults. The Diagnostic and Statistical Manual of Mental Disorders defines GAD as persistent and excessive worrying about various aspects of life that occurs most days for at least six months. This anxiety is excessive in both its intensity and its scope, impacting various aspects of life and causing significant impairment in daily functioning. Due to its high prevalence, there is a need for effective and safe treatments. Current guidelines for treatment of GAD recommend either monotherapy or combination therapy using pharmacological and/or psychosocial modalities. Pharmacological …

No. 24: Food And Health Security Among Burmese Migrant Domestic Workers In Singapore Amid Myanmar’S ‘Triple Crisis’, Brenda Yeoh, Franchesca Morais, Theodora Lam, Kristel Acedera, Bittiandra Chand Somaiah

Migration and Food Security (MiFOOD) Network

Migrating overseas to work as domestic workers is an increasingly important livelihood strategy for capital-poor women in Southeast Asian countries such as Myanmar. However, the recent COVID-19 pandemic and civil unrest in Myanmar has highlighted the entrenched precarities and uncertainties attached to this migration strategy. The health crisis has further heightened the importance of remittances and food security for migrants and their sending households. Food production, food systems and access to food supplies in the country have been especially hit by political instability, the energy crisis and inflation. This paper explores issues concerning the food and health security of female …

A Bundle Of Care For Prevention, Early Recognition, And Treatment Of Hyaluronic Acid Dermal Filler Associated Vascular Occlusion, Genny Sanders

Doctor of Nursing Practice Papers

Background: Hyaluronic acid (HA) dermal fillers, an injectable used for cosmetic use, are gaining popularity, and are expected to continue to do so in the projected future. With the rise in the number of patients seeking these procedures there is a correlated rise is adverse events, including the complication of vascular occlusion. Vascular occlusion has the potential for detrimental outcomes, and clinicians performing these procedures are responsible for educating patients about these risks. As whole, the healthcare community must be prepared.

Purpose: A quality improvement (QI) project was created to help clinicians prepare, prevent, recognize, and treat hyaluronic acid dermal …

Renal Mass Imaging Modalities: Does Body Mass Index (Bmi) Matter?, Young Son, Mark E Quiring, Raeann M Dalton, Brian Thomas, Noah Davidson, Dayna Devincentz, Collin Payne, Sahil H Parikh, Benjamin A Fink, Thomas Mueller, Gordon Brown

Rowan-Virtua School of Osteopathic Medicine Departmental Research

PURPOSE: Accurate measurement of renal mass size is crucial in the management of renal cancer. With the burdensome cost of imaging yet its need for management, a better understanding of the variability among patients when determining mass size remains of urgent importance. Current guidelines on optimal imaging are limited, especially with respect to body mass index (BMI). The aim of this study is to discern which modalities accurately measure renal mass size and whether BMI influences such accuracy.

METHODS: A multi-institutional chart review was performed for adult patients undergoing partial or radical nephrectomy between 2018 and 2021, with 236 patients …

Determining The Key Education Priorities Related To Heart Failure Care In Nursing Homes: A Modified Delphi Approach, James Mcmahon, David R. Thompson, Christine Brown Wilson, Loreena Hill, Paul Tierney, Jan Cameron, Doris S. F. Yu, Debra K. Moser, Karen Spilsbury, Nittaya Srisuk, Jos M. G. A. Schols, Mariëlle Van Der Velden-Daamen, Gary Mitchell

UK CARES Faculty Publications

There is currently a limited understanding of what nurses in nursing homes view as the key education priorities to support their ability to provide the appropriate care for residents with heart failure (HF). A modified Delphi technique was utilized to gain a consensus on the key education priorities for nurses working in nursing homes in Northern Ireland. An initial list of items (n = 58), across 19 domains, was generated using the findings of a scoping review and stakeholder interviews, and a review of available clinical guidelines. Two rounds of surveys were undertaken. Items were presented using a 5-point Likert …

Collegiate Esports Participation And Its Perceived Effects On Student Experience: A Phenomenological Study Of Collegiate Esports Teams, David Shimokawa

Dissertations

In an increasingly competitive higher education marketplace, institutions are seeking innovative strategies to grow or maintain their existing student populations. As student interests shift over time, institutions must stay informed of the rise and decline of various sporting activities and the impact those activities have on the student body. As more institutions look to utilize esports as a tool for recruiting and retaining students, the purpose of this qualitative phenomenological research study was to create new knowledge on the phenomenon of collegiate esports participation and its perceived effects on student experience. This study had 11 participants who were active undergraduate …

Covid-19 Prevention Behaviors And Dietary Habits Among Undergraduate Students: A Health Belief Model Approach, Doreen Liou

Department of Nutrition and Food Studies Scholarship and Creative Works

Physical and social disruptions resulted from the COVID-19 pandemic, affecting young adults in higher education. The purpose of this survey research is to unveil COVID-19 related beliefs using the Health Belief Model, and COVID-19 prevention behaviors, including self-reported fruit and vegetable consumption among university students. A cross-sectional survey was administered to 304 male and female undergraduate students from diverse ethnic backgrounds and majors at a New Jersey state university using convenience sampling. Variables measured included frequency of COVID-19 prevention behaviors (e.g.: wearing indoor mask, handwashing), and consumption of fruit and vegetables (dark green and orange vegetables) over the previous week. …

Diseases Of Cannabis Sativa And The Epidemiology And Molecular Diversity Of Neofusicoccum Parvum, Hannah V. Zima

Graduate Theses and Dissertations

Cannabis sativa has been an underutilized agricultural resource in the United States, largely due to federal regulations distinguishing marijuana from hemp. In 2018, Congress passed a Farm Bill, which defined hemp as C. sativa containing a tetrahydrocannabinol (THC) level of no more than 0.3%. As a result, commercial hemp production began in most states in 2019, including Arkansas, and was accompanied by numerous challenges like diseases and pests. The research on the epidemiology of diseases affecting C. sativa is limited, and understanding the pathogens is in its early stages in the U.S. For this study, an initial disease survey was …

Interactive Effects Between Bluetongue Virus Infection And Insecticide Exposures In Culicoides Sonorensis, Parker Mullins

Graduate Theses and Dissertations

Culicoides biting midges are common pests around the world of humans, livestock, and wildlife. In addition to nuisance blood feeding, they are also able to transmit pathogens to their hosts like bluetongue virus (BTV) and African horse sickness virus, which can be damaging in terms of both production economics and animal welfare. In order to protect humans and livestock from biting pests like Culicoides, a wide array of interventions is recommended, but chemical insecticides and repellent use are ubiquitous. For a multitude of reasons ranging from natural weathering of applied insecticides to the increase in resistance-associated mutations and behaviors in …

Fungal Pathogen Control And Microbial Ecology: Insights From Soybean Seed Production, Samantha Rigo Segalin

Graduate Theses and Dissertations

This study evaluated the effects of planting date (PD), seed vigor, and chemical seed treatments on the plant stand and yield of two soybean cultivars with different maturity groups (MGs) across four locations in Arkansas from 2018 to 2021. Early planting in early May (early PD) led to higher plant stands and yields compared to late planting in early June (late PD). The interaction between planting date and cultivar was significant, with both cultivars showing higher plant stands on early planting dates. Seed vigor and seed treatment also significantly impacted plant populations; high-vigor seeds planted early resulted in better stands …

Oats – Essentials For Growing A Successful Crop, Department Of Primary Industries And Regional Development, Western Australia

Grains and other field crops factsheets

Oats in Western Australia are grown for grain, hay, grazing, or silage. Each year, between 250,000 and 350,000 hectares are sown for grain production. This page provides essential management practices for growing a successful oat crop.

Clemson Commencement Program, August 2024, Clemson University

Clemson Commencement Programs

No abstract provided.

Why Are There So Many Definitions Of Eutrophication?, Alexandrine Pannard, Philippe Souchu, Christian Chauvin, Monique Delabuis, Chantal Gascuel-Odoux, Erik Jeppesen, Morgane Le Moal, Alain Ménesguen, Gilles Pinay, Nancy N. Rabalais, Yves Souchon, Elisabeth M. Gross

Faculty Publications

Because of the first observations in the 1900s of the oligotrophic and eutrophic states of lakes, researchers have been interested in the process that makes lakes become turbid because of high phytoplankton biomass. Definitions of eutrophication have multiplied and diversified since the mid-20th century, more than for any other ecological process. Reasons for the high number of definitions might be that the former ones did not sufficiently describe their causes and/or consequences. Global change is bringing eutrophication more into the spotlight than ever, highlighting the need to find consensus on a common definition, or at least to explain and clarify …

Lactoferrin And Lysozyme To Promote Nutritional, Clinical And Enteric Recovery: A Protocol For A Factorial, Blinded, Placebo-Controlled Randomised Trial Among Children With Diarrhoea And Malnutrition (The Boresha Afya Trial), Ruchi Tiwari, Kirkby Tickell, Emily Yoshioka, Joyce Otieno, Adeel Shah, Barbra Richardson, Lucia Keter, Maureen Okello, Churchil Nyabinda, Indi Trehan

Paediatrics and Child Health, East Africa

Introduction: Children with moderate or severe wasting are at particularly high risk of recurrent or persistent diarrhoea, nutritional deterioration and death following a diarrhoeal episode. Lactoferrin and lysozyme are nutritional supplements that may reduce the risk of recurrent diarrhoeal episodes and accelerate nutritional recovery by treating or preventing underlying enteric infections and/or improving enteric function.

Methods and analysis: In this factorial, blinded, placebo-controlled randomised trial, we aim to determine the efficacy of lactoferrin and lysozyme supplementation in decreasing diarrhoea incidence and improving nutritional recovery in Kenyan children convalescing from comorbid diarrhoea and wasting. Six hundred children aged 6–24 months with …