Digital Commons Network^™

A Stepwise Evaluation Of Pairing, Shaping, And Nonremoval Of The Spoon For Children With Autism And Feeding Difficulties, Nicole C. Demchuk

Theses & Dissertations

Feeding difficulties are pervasive for children with autism. The present study investigated the effects of a pairing intervention on cooperation with demands/acceptance of new foods, inappropriate behaviors, proximity to therapist, and indices of happiness for three children with autism and avoidant restrictive food intake disorder. When the pairing intervention alone was not effective to decrease inappropriate behaviors and increase acceptance of new foods, we implemented shaping procedures. Shaping was effective to increase acceptance of four new foods for two participants. For the third participant, we ultimately implemented nonremoval of the spoon procedures to decrease inappropriate behaviors and increase acceptance of …

Impacts Of Diets And Weight On Cognitive Decline Diseases Among The Middle-Aged Populations In Louisiana, Danielle Beamon

Walden Dissertations and Doctoral Studies

Cognitive decline is a public health concern since people are living longer, but little is known regarding how to prevent the progression of this condition; furthermore, current treatment options are not always effective after diagnosis. Previous research indicated obesity was associated with diminishing cognitive health, but most studies were conducted on individuals over the age of 65. The purpose of the study was to determine if there is a statistical correlation between cognitive decline and body mass index (BMI) among those between the ages of 40 and 64 years. Data from the 2015-2020 Behavioral Risk Factor Surveillance System Alzheimer’s Disease …

Evaluating The Effect Of Plantlet Age And Trichoderma Spp. Application On Acclimatization Of Boehmeria Nivea L. Gaud, Eva Aprilia, Anne Nuraini, Muhamad Kadapi

Jurnal Kultivasi

One of the crucial stages in the ramie plant (Boehmeria nivea L. Gaud) tissue culture is the acclimatization phase, which transitions between the in vitro and ex-vitro environments. Determining the appropriate age of plantlets and providing nutrients in the substrate play significant roles in the success of acclimatization. This research is conducted to determine the most suitable age of plantlets for acclimatization and assess the impact of providing nutrients through Trichoderma spp. application on the growth of ramie seedlings during the acclimatization phase. The experiment was conducted between January and March 2023 at the Screenhouse Bale Tatanen, Faculty of Agriculture, …

Intermittent Clearance Of P21-Highly-Expressing Cells Extends Lifespan And Confers Sustained Benefits To Health And Physical Function, Binsheng Wang, Lichao Wang, Nathan S Gasek, Chia-Ling Kuo, Jia Nie, Taewan Kim, Pengyi Yan, Junyu Zhu, Blake L Torrance, Yueying Zhou, Lisa C Flores, Colton Allen, Allison M Andrade, Chun Guo, Rachel L Cohn, Evan R Jellison, Jenna M Bartley, George A Kuchel, Sheng Li, Tamar Pirtskhalava, Tamar Tchkonia, Sumit Yadav, Laura Haynes, James L Kirkland, Yuji Ikeno, Ming Xu

Faculty, Staff and Student Publications

A key challenge in aging research is to extend lifespan in tandem with slowing down functional decline so that the life with good health (healthspan) can be extended. Here, we show that monthly clearance of a small number of cells, which highly express p21Cip1 (p21high), starting from 20 months improves cardiac and metabolic function, and extends both median and maximum lifespan in mice. Importantly, by assessing health and physical function of these mice monthly until death, we show that clearance of p21high cells improves physical function at all remaining stages of life, suggesting healthspan extension. Mechanistically, …

Undocumented And Unsupported: How College Students Navigate To Meet Their Basic Needs, Mario Alberto Gonzalez

Master's Theses

The cost of attendance at colleges and universities across the United States has risen exponentially year after year. Among these costs include tuition, lodging, food, textbooks, academic materials, and health care, many of which are considered “basic needs” that are ultimately essential for human survival. At the same time, certain groups of students continue to be marginalized and presented with additional barriers in accessing higher education in equitable ways. Undocumented students are one of these groups of students, and are the focus of this study. Although the passage of DACA in 2012 presented opportunities for approximately 800,000 undocumented students, it …

Influence Of Phosphate And Boron Addition To Mixed Liquid Fertilizer On The Growth And Yield Of Red Chili Cultivated In The Subsoil Layer, Stefina Liana Sari, Emma Trinurani Sofyan, Anni Yuniarti

Jurnal Kultivasi

This study assesses the impact of adding phosphate and boron in a mixed liquid fertilizer (MLF) on the growth and yield of red chili plants cultivated in a subsoil environment. The experiment was conducted to comprehend how these nutrients affect the performance of red chili plants, particularly when cultivated in less ideal conditions such as subsoil, a remnant of excavation for brick production. The research was carried out at the Ciparanje Garden of the Faculty of Agriculture, Universitas Padjadjaran. The research design employed a Randomized Completely Block Design with the following treatments: A = Control (degraded soil without fertilizer), B …

The Effects Of Online Chemistry-Themed Design-Based Stem Education On Preservice Science Teachers’ Stem Awareness, Emine Sahin Topalcengiz, Burcin Acar-Sesen

Curriculum and Instruction Faculty Publications and Presentations

The study investigated the impact of Chemistry-Focused Online Science, Technology, Engineering, and Mathematics (STEM) teacher education on the awareness of STEM among preservice science teachers. A one-group pretest–posttest quasi-experimental weak design was used to determine changes in preservice teachers’ STEM awareness. During the study, a 14-week Chemistry-Focused Online STEM course was provided to preservice science teachers. As part of this course, the theoretical knowledge about STEM was explained to students, and afterward, they completed two modules. Furthermore, preservice teachers also developed their chemistry-themed STEM lesson plans at the beginning of the course, after explaining theoretical knowledge about STEM at the …

Pkd1 Mutant Clones Within Cirrhotic Livers Inhibit Steatohepatitis Without Promoting Cancer, Min Zhu, Yunguan Wang, Tianshi Lu, Jason Guo, Lin Li, Meng-Hsiung Hsieh, Purva Gopal, Yi Han, Naoto Fujiwara, Darren P Wallace, Alan S L Yu, Xiangyi Fang, Crystal Ransom, Sara Verschleisser, David Hsiehchen, Yujin Hoshida, Amit G Singal, Adam Yopp, Tao Wang, Hao Zhu

Faculty, Staff and Student Publications

Somatic mutations in non-malignant tissues are selected for because they confer increased clonal fitness. However, it is uncertain whether these clones can benefit organ health. Here, ultra-deep targeted sequencing of 150 liver samples from 30 chronic liver disease patients revealed recurrent somatic mutations. PKD1 mutations were observed in 30% of patients, whereas they were only detected in 1.3% of hepatocellular carcinomas (HCCs). To interrogate tumor suppressor functionality, we perturbed PKD1 in two HCC cell lines and six in vivo models, in some cases showing that PKD1 loss protected against HCC, but in most cases showing no impact. However, Pkd1 haploinsufficiency …

Whole Genome Sequencing Based Analysis Of Inflammation Biomarkers In The Trans-Omics For Precision Medicine (Topmed) Consortium, Min-Zhi Jiang, Sheila M Gaynor, Xihao Li, Eric Van Buren, Adrienne Stilp, Erin Buth, Fei Fei Wang, Regina Manansala, Stephanie M Gogarten, Zilin Li, Linda M Polfus, Shabnam Salimi, Joshua C Bis, Nathan Pankratz, Lisa R Yanek, Peter Durda, Russell P Tracy, Stephen S Rich, Jerome I Rotter, Braxton D Mitchell, Joshua P Lewis, Bruce M Psaty, Katherine A Pratte, Edwin K Silverman, Robert C Kaplan, Christy Avery, Kari E North, Rasika A Mathias, Nauder Faraday, Honghuang Lin, Biqi Wang, April P Carson, Arnita F Norwood, Richard A Gibbs, Charles Kooperberg, Jessica Lundin, Ulrike Peters, Josée Dupuis, Lifang Hou, Myriam Fornage, Emelia J Benjamin, Alexander P Reiner, Russell P Bowler, Xihong Lin, Paul L Auer, Laura M Raffield, Nhlbi Trans-Omics For Precision Medicine (Topmed) Consortium, Topmed Inflammation Working Group

Faculty, Staff and Student Publications

Inflammation biomarkers can provide valuable insight into the role of inflammatory processes in many diseases and conditions. Sequencing based analyses of such biomarkers can also serve as an exemplar of the genetic architecture of quantitative traits. To evaluate the biological insight, which can be provided by a multi-ancestry, whole-genome based association study, we performed a comprehensive analysis of 21 inflammation biomarkers from up to 38 465 individuals with whole-genome sequencing from the Trans-Omics for Precision Medicine (TOPMed) program (with varying sample size by trait, where the minimum sample size was n = 737 for MMP-1). We identified 22 distinct single-variant …

Identification And Characterization Of A Skin Microbiome On Caenorhabditis Elegans Suggests Environmental Microbes Confer Cuticle Protection, Nadia B Haghani, Robert H Lampe, Buck S Samuel, Sreekanth H Chalasani, Molly A Matty

Faculty, Staff and Students Publications

In the wild, C. elegans are emersed in environments teeming with a veritable menagerie of microorganisms. The C. elegans cuticular surface serves as a barrier and first point of contact with their microbial environments. In this study, we identify microbes from C. elegans natural habitats that associate with its cuticle, constituting a simple “skin microbiome.” We rear our animals on a modified CeMbio, mCeMbio, a consortium of ecologically relevant microbes. We first combine standard microbiological methods with an adapted micro skin-swabbing tool to describe the skin-resident bacteria on the C. elegans surface. Furthermore, we conduct 16S rRNA gene sequencing studies …

Friend Social Network Size Moderates The Association Between Age And Physical Activity Across Adulthood, Ashley Kuzmik, Yin Liu, Yendelela Cuffee, Lan Kong, Christopher N. Sciamanna, Liza S. Rovniak

International Journal of Exercise Science

International Journal of Exercise Science 17(5): 1068-1082, 2024. Both physical activity and social network size decline as people age. However, limited research has examined if social network size and contact frequency differentially influence physical activity across the adult lifespan. This study aimed to assess if these social network characteristics moderated the relationship between age and physical activity level across adulthood. Multiple regression analyses were conducted to examine the main-effect association between age, past-week physical activity, and past-year physical activity, as well as the moderating effect of social network characteristics (i.e., friend network size, friend contact frequency, relative network size, and …

Cocaine As A Rare Cause Of Cholecystitis, Abdullah A. Orakzai, Osama Sherjeel Khan, Mustafa Shah, Syeda Sarah Raza, Mehr A. Orakzai, Muhammad H. Sharif

Advances in Clinical Medical Research and Healthcare Delivery

Cholecystitis, inflammation of the gallbladder, is diagnosed in approximately 200,000 people in the US each year. Cocaine is an illicit drug that is wildly abused in the US, GI complications such as acute pancreatitis, colitis, bowel perforation, mesenteric ischemia, and biliary tree obstruction have been reported in limited studies. To the best of our knowledge, there are no reported cases of cocaine-induced cholecystitis and no established treatment plans to date, however, we strongly believe that our patient’s cocaine use resulted in cholecystitis. Hence, we wanted to shed some light on the possible side effects of cocaine on the gall bladder.

The Role Of Osteopathic Manipulative Treatment In Neonatal Abstinence Syndrome, Kathryn Workman, Andrea M. Bodine, Md, Victoria Tuttle, Do

Advances in Clinical Medical Research and Healthcare Delivery

Context: The United States opioid epidemic has been an ongoing public health crisis. Nationally, maternal opioid use resulted in 82% increase in Neonatal Abstinence Syndrome (NAS), from 2010 to 2017. The opioid withdrawal process of NAS can lead to somatic dysfunctions. Osteopathic Manipulative Treatment (OMT) may decrease muscular and fascial strain in the body and provide relaxation to the NAS neonate.

Objectives: The objectives of this study were to compare the length of hospital stay (LOS) of NAS neonates who received OMT, and neonates given standard medical care without OMT and to evaluate the change in weight of the two …

Maternal Serum Branched-Chain Amino Acids In Early Pregnancy And Offspring Growth Patterns From 1 Year To 8 Years Of Age, Ninghua Li, Junhong Leng, Rui Zhang, Hui Wang, Weiqin Li, Shuang Zhang, Yijuan Qiao, Jing Li, Zhijie Yu, Gang Hu, Zhongze Fang, Xilin Yang

Population and Public Health Science Faculty Publications

No abstract provided.

Quality Improvement Project: The Bidirectional Relationship Among Type Ii Diabetes Mellitus And Periodontal Disease, Sarah Martinez

Doctor of Nursing Practice Projects

Individuals with Type 2 Diabetes Mellitus (T2DM) are at increased risk for oral health conditions such as periodontal disease. Moreover, there is an established bidirectional relationship that has been well documented in the literature among periodontal disease and T2DM. However, oral health is rarely being discussed with patients who have T2DM from the primary care setting. The objective for this Doctor of Nursing Practice (DNP) project was to bridge the gap in this area by assessing the efficacy of implementing an educational program to promote education and awareness in individuals with T2DM who are at risk for periodontal disease. This …

Studi In Silico Potensi Antikanker Senyawa Quercetin, Kaempferol, Dan Pelargonidin Terhadap Reseptor Histamin 1, Nur Aini, Fendy Hardian Permana, Siti Zaenab, Diani Fatmawati

Chimica et Natura Acta

Kanker menjadi permasalahan kesehatan dunia karena menyebabkan kematian dan diperkirakan akan terus mengalami peningkatan. Menurut The Global Cancer Observatory (2020) kasus kanker di Indonesia mencapai 6,89%. Pengobatan kanker dengan memblokir H1R (Histamine 1 Receptor) dengan antagonisnya berpotensi menurunkan proliferasi sel kanker. Senyawa flavonoid seperti quercetin, kaempferol dan pelargonidin dapat mereduksi dan berinteraksi dengan protein sehingga dapat dijadikan sebagai antagonis H1R antikanker. Studi in silico ini bertujuan mengetahui potensi senyawa quercetin, kaempferol dan pelargonidin terhadap H1R sebagai antikanker. Data senyawa quercetin, kaempferol dan pelargonidin dikumpulkan melalui database Pubchem dan struktur H1R dari database PDB dengan kode 3RZE. Penelitian ini merupakan penelitian …

An Insider’S Take On The German Sf Market, Gary Lynch

Mythcon

Gary Lynch has lived in Germany, and presents his “take.”

Adrenal Suppression From Vamorolone And Prednisone In Duchenne Muscular Dystrophy: Results From The Phase 2b Clinical Trial, Alexandra Ahmet, Rebecca Tobin, Utkarsh J. Dang, Raoul Rooman, Michela Guglieri, Paula R. Clemens, Eric P. Hoffman, Leanne M. Ward

Pharmacy Faculty Scholarship

Context: Vamorolone, a novel “dissociative” steroid, demonstrated similar efficacy in muscle function relative to prednisone 0.75 mg/kg/day but improved linear growth and bone turnover markers in a randomized trial of pediatric Duchenne muscular dystrophy (DMD). Objectives: To determine the frequency of adrenal suppression (AS) induced by vamorolone and prednisone in pediatric DMD and to assess cortisol thresholds using a monoclonal antibody immunoassay. Methods: Post hoc analysis of cortisol levels was performed on data from a randomized, double-blind, placebo- and prednisone-controlled 24- week trial of vamorolone with a 24-week crossover extension. Morning and ACTH-stimulated cortisol levels were measured using the Elecsys …

Advocating For The Role Of Occupational Therapy In A Community-Based Setting Through The Use Of Journaling For Individuals With Chronic Mental Illness, Taylor Muzik-Eversdijk

Department of Occupational Therapy Entry-Level Capstone Projects

Individuals who battle severe mental illness (SMI) experience a range of deficits that affect various aspects of daily life, including activities of daily living (ADLs), instrumental activities of daily living (IADLs), social participation, sleep and rest, education, work, leisure, and play. Research suggests that journaling can help individuals with SMI express their emotions and provide a healthy outlet for coping with symptoms. This doctoral capstone project aimed to identify the unique needs of individuals with SMI and explore how journaling and other occupational therapy (OT) interventions could expand the scope of practice within Boley Centers' assertive community treatment (ACT) teams …

Exploring The Interaction Between Klebsiella Pneumoniae And Clostridioides Difficile At The Mucosal Interface, Taylor D. Ticer

MUSC Theses and Dissertations

The gut microbiota plays a major role in human diseases. The impact of these microbes on human health comes not only from individual microbes but also from their interactions with each other. A prime example of this is Clostridioides difficile, an intestinal pathobiont that causes severe gastrointestinal illness. C. difficile works cooperatively with other gut bacteria, including Klebsiella pneumoniae. We hypothesized that K. pneumoniae would work synergistically with C. difficile and promote its pathogenesis. We screened over 40 K. pneumoniae strains to assess their interaction with the intestinal mucus layer, a key colonization site for C. difficile. …

Um Staff Share Expertise At National School Nutrition Conference, Edwin Smith

University of Mississippi News

OXFORD, Miss. – Several staff members of the Institute of Child Nutrition at the University of Mississippi shared their expertise a during the School Nutrition Association's recent annual national conference.

Socioeconomic Inequalities Between The Bronx And Other Counties In New York City, Mexican Studies Institute Cuny, Eliana Checo-Genaoa

CUNY Mexican Studies Institute

The Bronx, despite its proximity to the other boroughs of New York City, has the highest poverty rates among them. Using data from 2010 to 2022, this study examines the socioeconomic disparities between the Bronx and Brooklyn, Manhattan, Queens, and Staten Island. Key indicators analyzed include poverty levels, SNAP benefits, unemployment rates, median income, educational attainment, homeownership rates, business creation, and GDP per capita. Our study reveals that the Bronx has the highest poverty, unemployment, and SNAP benefit dependency rates, lower educational attainment, and the lowest median income and homeownership rates. Our findings underscore the persistent socioeconomic challenges faced by …

Reducing Hapi On A Medical Surgical Telemetry Unit, Emily Nicole Johansen

Master's Projects and Capstones

Abstract

Problem: Hospital-acquired pressure injuries (HAPI) are a global issue that harms patients, prolongs lengths of stay, and increases hospital costs and financial burdens. Because HAPIs are preventable, hospital organizations worldwide are implementing prevention strategies to improve the quality of care and quality of life and decrease costs associated with them.

Context: The 24-bed medical-surgical telemetry unit is one of five adult inpatient units within a Northern California hospital. The patient population includes an increased number of patients who are at risk of HAPI. The unit struggles with HAPI prevention, and the staff is challenged with implementing proper HAPI prevention …

Cooperative Extension’S Role In Addressing The Opioid Overdose Crisis: Best Practices From The Heart Initiative Model, Hailey Judd, Alise Williams Condie, Ashley C. Yaugher, Mateja R. Savoie-Roskos, Gabriela Murza, Timothy Keady, Sadie Wilde, Rachel Myrer, Maren Wright Voss

Journal of Extension

Cooperative Extension is in a unique position to address health and wellness concerns across the country, particularly in rural areas with local Extension services. One innovative model, the Health Extension: Advocacy, Research, and Teaching (HEART) Initiative, unites Extension, community organizations, and community members in collaborative activities to address the complex, multifaceted components of substance use disorder. The model utilized a multidisciplinary team and community-based participatory research (CBPR) approach with evidence-based practices to increase Extension’s abilities to guide and tailor programming to local needs and to create significant impacts. Cooperative Extension’s long history of engagement in the community, with state and …

Harnessing Cubesat Technology For Precision Pesticide Management In Egyptian Agriculture, Motaz El Sayed, Salem Abdou, Abdelhamid Sherif

Small Satellite Conference

This paper presents the development of an autonomous spraying robot designed to optimize agricultural practices through precise pesticide application, facilitated by the integration of real-time satellite data. The robot utilizes multispectral imaging from satellites, including NDVI and thermal data, to assess crop health and identify specific needs for intervention. The system aims to significantly reduce the volume of chemicals used in farming by targeting only the areas that require treatment, thus minimizing environmental impact while maintaining or enhancing crop yield. By employing advanced algorithms for data processing and machine operation, the robot autonomously navigates through fields, delivering pesticides in an …

Planned Gift Supports The Transformative Power Of Higher Ed, Tina H. Hahn

University of Mississippi News

OXFORD, Miss. – John Covert has lofty goals for the $3 million planned gift he committed to the University of Mississippi College of Liberal Arts and schools of Applied Sciences and Education.

Recentering Community Nutrition Education: A New Framework For Food Insecurity Understanding, Chasity Tompkins

Journal of Extension

While strategies may differ across geographical regions, FACS Extension professionals work to enhance nutrition education and increase food security in their communities. The four dimensions of food security developed by The Food and Agricultural Organization were reconceptualized to understand food security on an individual or at a community level. Using experiences from a summer internship with two urban counties, the EEUESA Model described here was designed to aid FACS Extension professionals in their efforts for nutrition education and to better understand how programming targets food security in their communities.

A Qualitative Description Of Graduate Students’ Perceived Decline In Physical Activity From Undergraduate School, Kristin M. Jett, Bryce T. Daniels, Max Brigance, Jessica L. Passarelli, Erin Howie

International Journal of Exercise Science

International Journal of Exercise Science 17(5): 1038-1055, 2024. Many university students, especially graduate students, are experiencing poor physical and psychological health. Thus, universities are initiating programs like Exercise is Medicine-On Campus (EIM-OC) to promote positive physical activity behavior to improve physical and mental health for primarily undergraduate university students. However, the influences on physical activity when transitioning from an undergraduate to a graduate student are unknown. To explore perceptions of if and how the physical activity levels of graduate students changed from their time as undergraduate students while considering environmental and lifestyle factors. METHODS: Using a qualitative, phenomenological research design, …

A Study On The Promising Ecotypes Of Secale Montaanum Guss., Bahram Peymani-Fard

IGC Proceedings (1977-2023)

Secale montamum (mountain rye) has been identified as a well-adapted species for rehabilitation of the substeppic rangelands of Iran. Further investigation on the quality and quantity values of different ecotypes of this species was required. The main objective of this study was to determine phenological stages, herbage yield and protein percentage of the promising native ecotypes of Secale montanum. This research was conducted on 7 ecotypes in which early growth started in late April and heading occurred in late May. Comparison of the 4-year total herbage yield indicated significant differences among the ecotypes, Secale momtanum (10091), which was the previously …

Forage Quality Determinants Of Mott Elephantgrass And Pennisetum Hybrids, L E. Sollenberger, J E. Moore, J A. Flores-C, C J. Chaparro, B Macoon

IGC Proceedings (1977-2023)

Daily gains of cattle grazing Mott elephantgrass (MB; Pennisteum purpureIum Schum.) arc approximately twice those obtained on other warm-season perennial grasses grown in Florida, USA, but plant characteristics responsible for the high forage quality of MB have not been identified. Three experiments were conducted during 1987- 1991 to determine factors that explain the high forage quality of MB and to assess the quality potential of P. purpureum x P. glaucum (L.) [R.Br.J x clephantgrass hybrids. Higher organic matter (OM) digestibility and intake of MB than Pensacola bahiagrass (PB; Paspalum nonatum Flugge) were associated with a lesser percentage of sclercnchyma (1.6 …