Digital Commons Network^™

14-Month-Old Female With Anti-Mda5 Juvenile Dermatomyositis Complicated By Liver Disease: A Case Report., Mitch Kinkor, Sameena Hameed, Alexander Kats, Voytek Slowik, Emily Fox, Maria Ibarra

Manuscripts, Articles, Book Chapters and Other Papers

BACKGROUND: Juvenile Dermatomyositis (JDM) is a rare disorder with subtypes associated with different myositis-specific antibodies (MSAs) including anti-MDA5. Hepatic involvement in JDM is rare and has not previously been documented in anti-MDA5 JDM. There is a lack of formal research on treatment protocols for anti-MDA5 JDM, though tofacitinib is a highly regarded emerging therapy.

CASE PRESENTATION: A previously healthy 14-month-old Hispanic female presented to a pediatric rheumatology clinic with eight months of worsening rash, weakness, periorbital edema, intermittent fevers, and weight loss. Her physical exam was notable for fever, thinning of hair, heliotrope rash, periorbital edema, violaceous macules on her …

Footprint Tools Tiptoeing Towards Nitrogen Sustainability, James N. Galloway, Elizabeth A. Castner, Elizabeth S M Dukes, Jessica Fox, Allison M. Leach

Faculty Publications

As we face multiple environmental crises (e.g. climate change, nutrient pollution, freshwater scarcity), there is often a disconnect between an entity’s activities and the pollution resulting from that activity. Footprint tools help address this disconnect. They are effective in educating people, institutions and communities on how their resource use results in environmental pollution and what we can do to moderate that pollution. These tools connect an entity’s activities with the associated pollution. Footprint tools are also constantly evolving. As we better understand how to best estimate emissions—especially from sources further removed like those from the supply chain—the guidance and methods …

Footprint Tools Tiptoeing Towards Nitrogen Sustainability, James N. Galloway, Elizabeth A. Castner, Elizabeth S M Dukes, Jessica Fox, Allison M. Leach

Faculty Publications

As we face multiple environmental crises (e.g. climate change, nutrient pollution, freshwater scarcity), there is often a disconnect between an entity’s activities and the pollution resulting from that activity. Footprint tools help address this disconnect. They are effective in educating people, institutions and communities on how their resource use results in environmental pollution and what we can do to moderate that pollution. These tools connect an entity’s activities with the associated pollution. Footprint tools are also constantly evolving. As we better understand how to best estimate emissions—especially from sources further removed like those from the supply chain—the guidance and methods …

Economic Development, Undernutrition And Diabetes, Kaivan Munshi, Swapnil Singh, Nancy Luke, Anu Mary Oommen

Cowles Foundation Discussion Papers

This research connects two seemingly unrelated facts that have recently been documented in developing countries, with important consequences for global health: (i) the weak association between nutritional status and income, and (ii) the elevated risk of diabetes among normalweight individuals. The model that we develop to reconcile these facts is based on a set point for body size that is adapted to (low) pre-modern food supply, but subsequently fails to adjust to rapid economic change. During the process of development, some individuals thus remain at their low-BMI set point, despite the increase in their income (food consumption), while others who …

Detecting Altered Hepatic Lipid Oxidation By Mri In An Animal Model Of Masld, Marc Mcleod, Mario C Chang, Anna Rushin, Mukundan Ragavan, Rohit Mahar, Gaurav Sharma, Arshee Badar, Anthony Giacalone, Max E Glanz, Vinay R Malut, Dalton Graham, Nishanth E Sunny, James A Bankson, Kenneth Cusi, Matthew E Merritt

Faculty, Staff and Student Publications

Metabolic dysfunction-associated steatotic liver disease (MASLD) prevalence is increasing annually and affects over a third of US adults. MASLD can progress to metabolic dysfunction-associated steatohepatitis (MASH), characterized by severe hepatocyte injury, inflammation, and eventual advanced fibrosis or cirrhosis. MASH is predicted to become the primary cause of liver transplant by 2030. Although the etiology of MASLD/MASH is incompletely understood, dysregulated fatty acid oxidation is implicated in disease pathogenesis. Here, we develop a method for estimating hepatic β-oxidation from the metabolism of [D

Design Considerations For Self-Management Technologies For People Living With Dementia And Informal Carers – Perspectives Of Healthcare Professionals And Charity Workers, Dympna O'Sullivan

Conference papers

Dementia is a neurodegenerative disorder that leads to decline in memory, language, reasoning, and the ability to perform daily activities. It is linked to poorer quality of life for the person with dementia and their informal (unpaid) carers. While early intervention and access to adequate care are critical in slowing dementia's progression and better managing associated symptoms, dementia is frequently only diagnosed at an advanced stage and care is often fragmented. To better understand how to meet the complex needs of persons living with dementia and their informal carers, 10 healthcare professionals and 10 charity workers from relevant community and …

Design Considerations For Self-Management Technologies For People Living With Dementia And Informal Carers - Perspectives Of Healthcare Professionals And Charity Workers, Dympna O'Sullivan, Julie Doyle, Orla Moran, Michael Wilson, Siobhan Oneill, Jonathan Turner, Suzanne Smith

Conference papers

Dementia is a neurodegenerative disorder that leads to decline in memory, language, reasoning, and the ability to perform daily activities. It is linked to poorer quality of life for the person with dementia and their informal (unpaid) carers. While early intervention and access to adequate care are critical in slowing dementia's progression and better managing associated symptoms, dementia is frequently only diagnosed at an advanced stage and care is often fragmented. To better understand how to meet the complex needs of persons living with dementia and their informal carers, 10 healthcare professionals and 10 charity workers from relevant community and …

Systematic Review On Isolation, Purification, Characterization, And Industrial Applications Of Thermophilic Microbial Α- Amylases, Rugaiyah A. Arfah, Sarlan Sarlan, Abdul Karim, Anita Anita, Ahyar Ahmad, Paulina Taba, Harningsih Karim, Siti Halimah Larekeng, Dorothea Agnes Rampisela, Rusdina Bte Ladju

Karbala International Journal of Modern Science

The α-amylase enzyme, sourced from diverse organisms, including plants, animals, and bacteria, plays a crucial role in multiple industries, notably food processing sectors like cakes, fruit juices, and starch syrup. Research identifies thermophilic organisms as prime sources of this enzyme thriving at temperatures ranging from 41°C to 122°C. The enzyme purification was carried out using liquid-liquid extraction, which involved the exchange of substances between two liquid phases that were immiscible or partially soluble. The optimal temperature for α-amylase was 45 to 90°C. The best pH for bacterial and fungal α-amylases ranged from 5.0 to 10.5 and 5.0 to 9.0. Based …

Examining Changes In Pain Sensitivity Following 8 Minutes Of Cycling At Varying Exercise Intensities, Brandi B. Antonio, Jeffrey Stout, Danielle Sterner, Abigail Anderson, David Fukuda

International Journal of Exercise Science

International Journal of Exercise Science 17(7): 1337-1351, 2024. This study assessed the effect of an eight-minute cycling intervention using varying intensities on exercise-induced hypoalgesia (EIH). The main objective of this study was to examine the effect of varying intensities on pressure pain threshold (PPT) and heat pain threshold (HPT) at the thigh and forearm, tested pre- and post-cycling intervention. Healthy male participants (n = 16) performed a graded exercise test on a cycle ergometer to establish their peak power output (PPO). In subsequent visits, participants completed five different 8-minute cycling interventions, with intensities randomly assigned to one of three …

Perceptions Of Peer And Parental Support: Feasibility Of A Physical Activity Intervention For Adolescent Girls, Avery G. Douglas, Deirdre Dlugonski, Johanna M. Hoch

International Journal of Exercise Science

International Journal of Exercise Science 17(5): 1352-1360, 2024. Physical activity (PA) has a wide range of health benefits. Children with high levels of social support are more likely to achieve adequate levels of PA. The purposes of this pilot study were to examine the impact of an after-school intervention on perceived peer and parental support among adolescent girls and to identify correlates of support to explore in future studies to increase PA. Seventeen low-active girls in 6th–7th grade were recruited from a local middle school to participate in an 8-week intervention where they were exposed to various types of PA …

Wmdds Bulletin Summer 2020

West Michigan District Dental Society Bulletin

In the Summer 2020 issue, the reader will find the following feature articles:

• Ask an Expert: What Does This New Legislation Around PPP Mean for Me?
• COVID-19 Pandemic Results in Severe Operating Room Access Limitations for Pediatric Dentists

Also included are your monthly tripartite update, news from West Michigan counties, the President's Message and Editor's Letter.

A Diagnostic Challenge In Midbrain Lesions: Nothnagel Syndrome, Sanjith Krishna S, Lokesh M

Vedam- 2024, The Academic Fest and Undergraduate Medical Conference of KMC, Manipal

No abstract provided.

Kikuchi’S Disease With Inguinal Necrotizing Lymphadenitis: A Case Report, Kaushik Rajesh Joshi, Haricharan K R, Rahul R, Nirupama M, Asha Benakappa

Vedam- 2024, The Academic Fest and Undergraduate Medical Conference of KMC, Manipal

No abstract provided.

Tiny Warrior’S Triumph: Navigating The Nicu Journey Of A 780 Grams Baby, Aditi Kishore, Shradha .

Vedam- 2024, The Academic Fest and Undergraduate Medical Conference of KMC, Manipal

No abstract provided.

Hypertriglycerdemia In Pregnancy: Clinical Implications And Management Strategy, Navya Pradeepgoud Patil, Ramesh Kumar, Ashiwini Annikumar

Vedam- 2024, The Academic Fest and Undergraduate Medical Conference of KMC, Manipal

No abstract provided.

A Case Of Crohn’S Disease With Neurological Extra Intestinal Manifestations, Srikar Giduthuri, Shivashankara .

Vedam- 2024, The Academic Fest and Undergraduate Medical Conference of KMC, Manipal

No abstract provided.

Exploration Of Insomnia In Advanced Cancer: A Retrospective Chart Review, Eugenie Spiguel

ETD Collection

Background/Significance: Insomnia is a common symptom in the oncology population and can impact other symptoms such as fatigue, pain, and depression. Although there has a been a significant amount of research on insomnia in cancer survivors, little is known about insomnia in people with advanced cancer.

The Impact Of Health And Environmental Messaging With And Without Product Filtering In Complex Retail Markets: The Case Of Pulses, Christopher R. Gustafson, Henriette Gitungwa, Sushil C. Sapkota, Devin J. Rose

Department of Agricultural Economics: Faculty Publications

Introduction: Multiple barriers exist to healthy and environmentally sustainable food choices. Limited consumer understanding of the health and environmental implications of food choices complicates their abilities to make choices that lead to desired outcomes. The complexity of the retail environment itself may crowd out less immediate motivations to address health or environment. Even if consumers understand general impacts of food choices on health and environmental outcomes, there may be non-negligible time and search costs to identifying the products that meet consumers’ needs. In many food categories, the foods containing attributes that help achieve health and sustainability outcomes may represent …

Investigating The Synergistic Antibacterial Effects Of Ulva Lactuca And Fucus Vesiculosus Extracts On The Growth Of Staphylococcus Epidermidis, Bryan Lee

Journal of the South Carolina Academy of Science

This study investigates the antibacterial properties of extracts from marine macroalgae, Ulva lactuca (green algae) and Fucus vesiculosus (brown algae), individually and in combination, with a focus on combating antibiotic-resistant pathogens. The escalating challenge of antibiotic resistance requires the exploration of alternative antimicrobial agents derived from natural sources. Utilizing the agar well diffusion method, the study evaluates the inhibitory effects of the algae extracts on Staphylococcus epidermidis. Chloramphenicol serves as the positive control, while 5% dimethyl sulfoxide acts as the negative control. The combination of Ulva lactuca and Fucus vesiculosus extracts did not exhibit a significantly greater antibacterial effect than …

Impact Of Generative Ai In Nutrition Education & Counseling, Erin Lauckner

AI Assignment Library

This assignment helps nutrition students investigate common nutrition questions answered by generative AI.

Beyond Covid: Towards A Transdisciplinary Synthesis For Understanding Responses And Developing Pandemic Preparedness In Alaska, Taylor P. Van Doren, Ryan A. Brown, Guangqing Chi, Patricia Cochran, Katie Cueva, Laura Eichelberger, Ruby Fried, Stacey Fritz, Micah B. Hahn, Ron Heintz, Davin Holen, Andrey N. Petrov

Faculty Publications

Pandemics are regularly occurring events, and there are foundational principles of pandemic preparation upon which communities, regions, states, and nations may draw upon for elevated preparedness against an inevitable future infectious disease threat. Many disciplines within the social sciences can provide crucial insight and transdisciplinary thinking for the development of preparedness measures. In 2023, the National Science Foundation funded a conference of circumpolar researchers and Indigenous partners to reflect on COVID-19-related research. In this article, we synthesise our diverse social science perspectives to: (1) identify potential areas of future pandemic-related research in Alaska, and (2) pose new research questions that …

Exposure And Connectedness To Natural Environments: An Examination Of The Measurement Invariance Of The Nature Exposure Scale (Nes) And Connectedness To Nature Scale (Cns) Across 65 Nations, 40 Languages, Gender Identities, And Age Groups, Viren Swami, Mathew P. White, Martin Voracek, Ulrich S. Tran, Toivo Aavik, Hamed Abdollahpour Ranjbar, Sulaiman Olanrewaju Adebayo, Reza Afhami, Oli Ahmed, David A. Frederick

Psychology Faculty Articles and Research

Detachment from nature is contributing to the environmental crisis and reversing this trend requires detailed monitoring and targeted interventions to reconnect people to nature. Most tools measuring nature exposure and attachment were developed in high-income countries and little is known about their robustness across national and linguistic groups. Therefore, we used data from the Body Image in Nature Survey to assess measurement invariance of the Nature Exposure Scale (NES) and the Connectedness to Nature Scale (CNS) across 65 nations, 40 languages, gender identities, and age groups (N = 56,968). While multi-group confirmatory factor analysis (MG-CFA) of the NES supported …

The Effects Of Social Isolation On People With Dementia And The Use Of Arts As Connection, Emily Olive

Expressive Therapies Capstone Theses

During the COVID-19 pandemic, many states issued quarantines and social isolation policies. While this impacted the well-being and mental health of everyone, it had an increased effect on the elderly population and, more specifically, those living with dementia. Social isolation has been shown to cause a quicker progression of dementia symptoms, increase anxiety and depressive symptoms, and worsen chronic health issues. Before the pandemic, research has agreed that a way to combat the progression of dementia and lower the symptoms is through socialization. A critical review of the literature found that the arts may be used to form connections between …

Curcumin Alleviates Inflammatory Effects Of Ketamine Anesthesia In Postnatal Rats, Soroush Afshar Ghahremani, Abbas Raisi, Sohrab Minaei Beirami, Houman Kahroba, Mahnaz Mardani, Omid Dezfoulian, Vahideh Tarhriz

School of Graduate Studies Faculty Publications

Curcumin has been employed in traditional medicine for over a millennium to treat various ailments, and its global use is now widespread. Chinese medicine relies heavily on curcumin as a primary element and uses it to cure infectious diseases, skin disorders, depression, and stress. It has cardioprotective, neuroprotective, and anti-diabetic properties, as well as pharmacological effects on disorders like type II diabetes, atherosclerosis, and human immunodeficiency virus replication. The anti-cancer activity of curcumin has been studied extensively with notable improvements in gastrointestinal, melanoma, urogenital, breast, and lung malignancies. We investigated the anti-inflammatory effects of curcumin on expression of tumor necrosis …

Investigating The Use Of Lesson Study As A Professional Development Model For 4-H Educators At 1890 Land Grant Universities, Cynthia Pierfax, Travella Free, Tiffany Franklin, Manola Erby, Lynn Schmitt-Mcquitty, C L. Meehan, Martin H. Smith

Journal of Extension

There is a defined need to provide accessible and effective professional development for 4-H educators. Lesson study is a Community of Practice-based approach to educator professional development. Prior research has shown lesson study to be effective with 4-H staff, adult volunteers, and teen volunteers. This inquiry, a multi-site case study, was designed to investigate the application of lesson study in authentic contexts with 4-H county agents from 1890 land-grant universities. Quantitative and qualitative measures revealed improved preparedness, participation, and camaraderie among participating educators. Other benefits to participants included improved lesson planning and implementation.

The De Winter Pattern In A Single Precordial Lead Caused By High-Grade Stenosis Of The Proximal Left Anterior Descending Artery With Plaque Rupture: A Case Report, Zhizhou Song, Yuehong Huo, Qi Wu, Xinjian Yu, Youdong Yang, Zejun Meng, Xia Li

Children’s Nutrition Research Center Staff Publications

The de Winter electrocardiogram (ECG) pattern indicates severe stenosis or occlusion of the left anterior descending artery (LAD). We present a 72-year-old female with 1.5-h chest pain. Angiography and optical coherence tomography (OCT) revealed 90 % LAD stenosis with plaque rupture, but no ST-segment elevation in the precordial leads. The de Winter pattern, characterized by upsloping ST-segment depression in V1-V6, appeared only in lead V2. Following successful percutaneous coronary intervention (PCI), the de Winter pattern disappeared. This case underscores the significance of the de Winter pattern in one precordial lead, necessitating prompt angiography and PCI for improved patient outcomes.

Phototaxis Is A Satiety-Dependent Behavioral Sequence In Hydra Vulgaris, Soonyoung Kim, Krishna N Badhiwala, Guillaume Duret, Jacob T Robinson

Faculty, Staff and Students Publications

Understanding how internal states such as satiety are connected to animal behavior is a fundamental question in neuroscience. Hydra vulgaris, a freshwater cnidarian with only 12 neuronal cell types, serves as a tractable model system for studying state-dependent behaviors. We found that starved hydras consistently move towards light, while fed hydras do not. By modeling this behavior as a set of three sequences of head orientation, jump distance and jump rate, we demonstrate that the satiety state only affects the rate of the animal jumping to a new position, while the orientation and jump distance are unaffected. These findings yield …

What Inclusive Instructors Do: A Book Review, Marlene Graf

Empowering Teaching Excellence Conference

In the book, "What Inclusive Instructors Do" (published in 2021), authors Tracie Addy et el focus on principles and practices for excellence in college teaching and offer several recommendations for creating an inclusive classroom. In the preface, they explain to the reader that this book emerged as a result of changes to the educational landscape as a result of COVID and online instruction. This book was also a courageous response to the racial tension and violence that escalated during the pandemic.

Unleashing Potential: Strategies For Online Learners To Conquer Procrastination And Maximize Engagement, Maria Givler, Nikki Kendrick, Lacie Peterson

Empowering Teaching Excellence Conference

As the landscape of education continues to evolve, the shift towards online learning has become more prevalent. While online courses offer flexibility and accessibility, it also presents unique challenges, with one of the most common hurdles being procrastination. In the absence of traditional classroom structures and weekly deadlines, students may struggle to manage their time effectively. This session aims to address the critical issue of procrastination in online learning environments and explore innovative strategies to enhance student engagement. We will delve into the development of tools and techniques that empower learners to stay on track, maintain motivation, and successfully achieve …

The Courage To Teach: How To Keep Showing Up In Ways That Matter, Marlene Graf, Christian Bolander, Rose Judd-Murray, Alyssa Reidhead, Lance Stott

Empowering Teaching Excellence Conference

This workshop will ask you to think about ways that you can incorporate study strategies so that students can become more active and successful. Join us as we embark on the path toward enriched learning experiences and sustained academic success.