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Understanding Necrotizing Enterocolitis Endotypes And Acquired Intestinal Injury Phenotypes From A Historical And Artificial Intelligence Perspective., Alain Cuna, Navin Kumar, Venkatesh Sampath

Manuscripts, Articles, Book Chapters and Other Papers

Necrotizing enterocolitis (NEC) remains a devastating disease in preterm and term neonates. Despite significant progress made in understanding NEC pathogenesis over the last 50 years, the inability of current definitions to discriminate the various pathophysiological processes underlying NEC has led to an umbrella term that limits clinical and research progress. In this mini review, we provide a historical perspective on how NEC definitions and pathogenesis have evolved to our current understanding of NEC endotypes. We also discuss how artificial intelligence-based approaches are influencing our knowledge of risk-factors, classification and prognosis of NEC and other neonatal intestinal injury phenotypes.

Polycystic Ovarian Syndrome And Homoeopathic Management: A Case Series, Padmalaya Rath, Priya Gautam, Amiyananda Dev Goswami, Shib Narayan Jana

Indian Journal of Research in Homoeopathy

Introduction: Polycystic ovary syndrome (PCOS) is a disorder of chronically abnormal ovarian function and hyperandrogenism (abnormally elevated androgen levels). It is manifested by irregular menstrual cycles, polycystic ovaries, acne, excess unwanted hair growth, obesity, etc. PCOS can affect a female’s fertility. The global prevalence of PCOS varies from 5% to 18%, with an average prevalence of 276·4 cases per 100,000 people in Europe. The prevalence of PCOS in India ranges from 3.7 to 22.5% depending on the population studied. Case Summary: This is a case series of five patients suffering from PCOS, assessed on the basis of intermenstrual duration, acne …

No. 105 An Order To Provide Relief To Victims Of Severe Weather And Flooding In Tennessee, Bill Lee

Executive Orders

No abstract provided.

2024 - Faculty & Staff Research Symposium, Elizabeth Outka, Lidia Radi

Faculty and Staff Research Symposium Programs

[Excerpt from the "Welcome"]

"Dear Colleagues,

Welcome to the second Faculty and Staff Research Symposium!

We are delighted to see such enthusiasm for this event, following the extraordinary response to last year’s inaugural Symposium. It is truly a testament to the vibrant, engaged community we have here — a group of colleagues deeply committed to ideas, creativity, and collaboration. Across our campus, faculty and staff continue to push the boundaries of research, to design and maintain new learning and gathering spaces, to craft remarkable art and performances, and to develop innovative programs that enrich our collective experience. . . . …

Phenotypic Correlation, Path Analysis, And Quantitative Trait-Based Selection Of Elite Wheat Genotypes Under Heat Stress Conditions In The Terai Region Of Nepal, Radhakrishna Bhandari, Binod Panthi, Shivalal Nyaupane, Sandesh Shrestha, Prabin Sharma, Rajesh Kumar Gupta, Sansar Sahani, Mukti Ram Poudel

Makara Journal of Science

Wheat is one of the most important cereal crops worldwide, but the production and productivity of wheat is affected by heat stress. A field experiment using an alpha lattice design with seven blocks was conducted on 35 elite wheat genotypes in the Terai region of Nepal to identify the most appropriate trait resulting in a high-yielding wheat genotype with high tolerance to heat stress. Correlation analysis revealed that booting-to-heading duration (BtoH), booting-to-anthesis duration (BtoA), plant height (Ph), spike length (SL), spike weight (SW), thousand grain weight (TGW), straw yield (SY), and total biomass yield (TY) had a significant positive correlation …

Antibacterial Activities And Chemical Composition Of Essential Oils From Sweet Orange (Citrus Sinensis), Lemon Grass (Cymbopogon Citratus), And Lime (Citrus Aurantifolia) Peels, Olumide Omoboye, Toyosi Sotola, Olaoye Balogun, Ololade Bamigbade, Olusola Oluwole, Adebowale Odeyemi, Anthonia Oluduro

Makara Journal of Science

This study investigated the chemical composition and antibacterial activities of lime Citrus aurantifolia (Cc) and lemon grass Cymbopogon citratus (Ca) essential oils (EOs). Standard methods were used to determine their minimum inhibitory concentrations (MIC) and minimum bactericidal concentrations (MBC), and gas chromatography–mass spectrometry was used to determine their composition. Each EO and their combination showed promising results in treating test bacterial infections. Cc EO showed the largest inhibition zone diameter (43 mm) against Staphylococcus aureus and Serratia marcescens, and Ca EO showed the largest (30 mm) and smallest (12 mm) inhibition zone diameters against Bacillus stearothermophilus and S. marcescens …

The "Pros" Of Probiotics: A Review Of Probiotics Place In Therapy, Kelley Maberry, Hanh Nguyen, Connor Quinter, Justine Magalona

Transformative Medicine

As different probiotic supplements become increasingly seen in the market, questions regarding their use for gut health from patients rises as well. Because these supplements do not require FDA approval, their safety and efficacy is often unknown and limited research available poses an even greater challenge for healthcare providers when prompted with questions regarding their use. This article summarizes evidence-based recommendations provided by the American Gastroenterological Association (AGA) and the World Gastroenterology Organization (WGO). Of the conditions discussed, supportive evidence on the use of probiotics is mostly seen in the prevention of C. diff associated diarrhea, prevention of antibiotic associated …

Catastrophic Spontaneous Uterine And Bladder Rupture In An Unscarred Uterus, Nathanael N. Hoskins Do, Kathryn Brandt Do, Tory Peterson Md

Transformative Medicine

Introduction:

Uterine rupture during pregnancy is a rare event which can be life-threatening for both the patient and the fetus. This case report describes a rare complication of uterine rupture which ultimately required a hysterectomy and extensive urologic reconstruction.

Case Description:

A 36-year-old patient presented to the hospital after term pre-labor rupture of membranes. The patient underwent induction of labor which ultimately resulted in a uterine rupture in an unscarred uterus. The rupture extended into the posterior bladder wall, right ureter, urethra, and anterior vaginal wall, resulting in a vesicovaginal fistula. The patient required a cesarean hysterectomy due to the …

It’S A Question At The ‘Root’ Of The Problem: Fungal Associations Of Dionaea Muscipula (Venus’ Flytrap) Roots In Its Native Habitat, Anna A. Carnaggio, Michelle M. Barthet

Biology

Carnivorous plants survive in harsh habitats with limited nutrients and a low pH. Much focus has been placed on carnivorous trap evolution as the primary mechanism to increase nutrient acquisition through insect digestion. Soil microbiome, however, may also play a pertinent role in nutrient acquisition influencing plant vigor and overall success. Dionaea muscipula, commonly known as the Venus’ flytrap, is endemic to rims of the Carolina Bays located in southeast North Carolina and northeast South Carolina, where D. muscipula survives in nutrient poor soils with a vestigial root system. We utilized a combination of microscopy, plating, and metagenomics, to investigate …

Understanding The Drivers Of Industry 4.0 Technologies To Enhance Supply Chain Sustainability: Insights From The Agri-Food Industry, Guoqing Zhao, Xiaoning Chen, Paul Jones, Shaofeng Liu, Carmen Lopez, Leonardo Leoni, Denis Dennehy

Plymouth Business School

The sustainability of agri-food supply chains (AFSCs) is severely threatened by regional and global events (e.g., conflicts, natural and human-made disasters, climate crises). In response, the AFSC industry is seeking digital solutions using Industry 4.0 (I4.0) technologies to enhance resilience and efficiency. However, why I4.0 adoption remains stubbornly low in the agri-food industry remains poorly understood. To address this gap, this study draws on middle-range theory (MRT) and uses thematic analysis, the fuzzy analytic hierarchy process, total interpretive structural modelling, and fuzzy cross-impact matrix multiplication applied to classification to produce insights from nine case studies in China that have invested …

The Current - Volume 35 Issue 3, Nova Southeastern University

Student Newspapers

No abstract provided.

Impact Of Sinus Surgery In People With Cystic Fibrosis And Chronic Rhinosinusitis In The Era Of Highly Effective Modulator Therapy: Protocol For A Prospective Observational Study, Christine M. Liu, Jakob L. Fischer, Jeremiah A. Alt, Todd E. Bodner, Naweed I. Chowdhury, Anne E. Getz, Peter H. Hwang, Adam J. Kimple, Timothy L. Smith, Multiple Additional Authors

Psychology Faculty Publications and Presentations

Introduction Cystic fibrosis (CF) is commonly complicated by chronic rhinosinusitis (CRS). Despite highly effective management options, CRS in people with CF (PwCF+CRS) may be refractory to medical therapy, eventually requiring endoscopic sinus surgery. The impact of sinus surgery on pulmonary, quality of life (QOL), and other outcomes in PwCF+CRS in the expanding era of highly effective modulator therapy has not been fully elucidated. This study aims to determine if endoscopic sinus surgery can offer superior outcomes for PwCF+CRS when compared to continued medical treatment of CRS. Methods and analysis This multi-institutional, observational, prospective cohort study will enroll 150 adults with …

The Effect Of A Self-Guided Simulation Tool On Anxiety Related To Clincal Practice Among Baccalaureate Nursing Students During Their First Clinical Rotation, Karen M. Vargas

Dissertations

Research has demonstrated that anxiety can have a detrimental effect on learning and performance. Of great concern is the impact of anxiety on nursing students. By extension, additional research has shown that nursing students experience extremely high levels of anxiety, higher than many students in other programs. Specifically, nursing students have moderate to severe levels of anxiety due to many aspects of the educational program, but particularly when beginning clinical practice. Anxiety when beginning clinical practice among nursing students can cause negative outcomes in learning and performance. That is, when nursing students experience severe anxiety, they may experience the inability …

September 26, 2024, The Daily Mississippian

Daily Mississippian (all digitized issues)

No abstract provided.

Treatment Outcomes Among Patients With A Positive Candida Culture Close To Randomization Receiving Rezafungin Or Caspofungin In The Restore Study, Alex Soriano, Marin Kollef, Et Al.

2020-Current year OA Pubs

BACKGROUND: Rezafungin, a novel, once-weekly echinocandin for the treatment of candidemia and/or invasive candidiasis (IC) was noninferior to caspofungin for day 30 all-cause mortality (ACM) and day 14 global cure in the phase 3 ReSTORE trial (NCT03667690). We conducted preplanned subgroup analyses for patients with a positive culture close to randomization in ReSTORE.

METHODS: ReSTORE was a multicenter, double-blind, double-dummy, randomized trial in patients aged ≥18 years with candidemia and/or IC treated with once-weekly intravenous rezafungin (400 mg/200 mg) or once-daily intravenous caspofungin (70 mg/50 mg). This analysis comprised patients with a positive blood culture drawn between 12 hours before …

Untargeted Metabolomic Biomarker Discovery For The Detection Of Ectopic Pregnancy, Onur Turkoglu, Ayse Citil, Ceren Katar, Ismail Mert, Robert A Quinn, Ray O Bahado-Singh, Stewart F Graham

Faculty, Staff and Students Publications

Ectopic pregnancy (EP) is the leading cause of maternal morbidity and mortality in the first trimester. Using an untargeted metabolomic approach, we sought to identify putative plasma biomarkers using tandem liquid chromatography-mass spectrometry for the detection of tubal EP. This case-control study included the prospective recruitment of 50 tubal EP cases and 50 early intrauterine pregnancy controls. To avoid over-fitting, logistic regression models were developed in a randomly selected discovery group (30 cases vs. 30 controls) and validated in the test group (20 cases vs. 20 controls). In total, 585 mass spectral features were detected, of which 221 molecular features …

Molecular Testing Of Environmental Samples As A Potential Source To Estimate Parasite Infection, Rojelio Mejia, Barton Slatko, Cristina Almazan, Ruben Cimino, Alejandro Krolewiecki, Natalia Montellano Duran, Jacob Edwin Valera Aspetty, Paola Andrea Vargas, Chiara Cássia Oliveira Amorim, Stefan Michael Geiger, Ricardo Toshio Fujiwara, Juan David Ramirez, Luz Marina Llangarí-Arizo, Irene Guadalupe, Liliana E Villanueva-Lizama, Julio Vladimir Cruz-Chan, María Leticia Ojeda, Eva Mereles Aranda, Sandra Ocampos Benedetti, Maritza Dalí Camones Rivera, Eddyson Montalvo Sabino, Carlos Pineda, Eric J Wetzel, Philip J Cooper

Faculty, Staff and Students Publications

We discuss the potential usefulness of molecular testing of soil, dust, and water samples to detect medically important parasites, and where such testing could be used to supplement stool sampling in humans. A wide variety of parasites including protozoa and helminths, many of which are zoonotic, have an important infection reservoir in the environment. In some cases, this environmental period is essential for further parasite development. We describe the progress in implementing methods for the molecular detection of these parasites in soil across eight collaborating centers in Latin America and represent a variety of potential applications in improving our understanding …

A Meta-Analysis Comparing Surgical Site Wound Infection Following Single-Incision Versus Multiple-Incision Video-Assisted Thoracoscopic Surgery Lobectomy For Patients With Lung Cancer, Zainab Ayad

Al-Mustaqbal Journal of Pharmaceutical and Medical Sciences

Background

A meta-analysis was conducted to evaluate the impact of single-incision (SI) versus multiple-incision (MI) video-assisted thoracoscopic surgery (VATS) lobectomy on surgical site wound length (SSWL) and surgical site wound infection (SSWI) in lung cancer (LC) patients.

Methods

Inclusive literature research till March 2023 was done and 598 interconnected researches were revised. The 8 picked researches, enclosed 1542 LC persons were in the utilized researches' starting point, 310 of them were utilizing SI, and 232 were utilizing MI. Odds ratio (OR) and 95% confidence intervals (CIs) were utilized to appraise the effect of SI compared to MI VATS lobectomy for …

Effect Of Antibiotic Prophylaxis On Surgical Site Wound Infection In Third Molar Surgery: A Meta-Analysis, Mohamed Atif Elkholy, Sayed Rashed Fashkal

Al-Mustaqbal Journal of Pharmaceutical and Medical Sciences

The objective of this meta-analysis is to assess the impact of antibiotic prophylaxis (AP) on surgical site wound infection (SSWI) throughout third molar surgery (TMS).

A meta-analysis was conducted using examinations that compared AP to placebo for TMS from different languages that satisfied the inclusion criteria. Applying dichotomous random or fixed effect models, the findings of these studies were analysed, and the Odd Ratio (OR) was calculated with 95% confidence intervals (CIs).

A total of 18 studies conducted between 2001 and 2023 were included in the present analysis. These studies initially included 4063 individuals with TMS.

A substantial reduction in …

Evaluation Of Nursing Care Documentation And Administration At Emergency Unite: Comparative Study, Ali Refak Lazem, Huda Baker Hassan

Al-Mustaqbal Journal of Pharmaceutical and Medical Sciences

Objectives: to evaluate of nursing care documentation and administration at emergency unite, and find the relationship between Nursing care documentation and administration and demographic characteristic of nurses.

Method: An Observational design study was conducted from the 25 December 2023 to 30 April 2024. The study setting was conducted at the emergency department in AI-Hussein Teaching Hospital, Al-shatra General Hospital in Dhi-Qar governorate/Iraq. Study Sample A convenient sample (non-probability) involving (103 nurses:60 in Al-Hussien Hospital and 43 in Al-Shatra Hospital). The practices were evaluated by using the self-report questionner and observational checklist. The data analysis through descriptive and interferential statistics …

Let’S Eat Healthy: Piloting A Brief Interactive Nutrition Session For High School Students – Role Of A Physician, Michaela Q. Ramirez Iglesia, Chelsea Chang

Research Colloquium

Background: 26.2% of Hispanic American children are obese, while 19.7% of children in the United States are obese. We developed and delivered a 30-minute interactive nutrition session for high school students including a nutrition knowledge assessment in the predominantly Hispanic region of South Texas, the Rio Grande Valley.

Methods: We designed the curriculum to teach high school students about the health impacts of sugar-sweetened beverages, the importance of eating whole foods, and tools for making healthy choices. We presented “Let’s Eat Healthy” to 70 high school students as part of a day-long interprofessional conference by University of Texas Rio Grande …

Revealing The Key Ingredient: Understanding How Teachers In Challenging School Environments Navigate School Culture To Enhance Learner Retention, Babalwa Kafu-Quvane Dr

Journal of Curriculum, Teaching, Learning and Leadership in Education

This paper explores teachers’ professional practices to gain a thorough grasp and a deep understanding of what it takes to retain learners in an environment where most schools fail to do so. I approach the study using a qualitative multiple case study design and position it within the interpretive paradigm. I purposively selected 50 post-level one teachers from five schools. Cavanagh and Dellar’s theory on culture of school improvement, which emphasizes the transformation of schools into learning communities through social interaction, interpersonal relationships, and support among various stakeholders, including parents, teachers, and learners, was used as theoretical lens for this …

The Effects Of High-Intensity Functional Training On The Perceptions Of Exercise In Middle-Aged Females: A Pilot Study, Halle N. Brin, Baylie G. Sigmund, Nathan D. Dicks, Kathryn J. Deshaw, Tanis J. Walch, Michael J. Carper, Allison M. Barry

International Journal of Exercise Science

International Journal of Exercise Science 17(5): 1392-1405, 2024. The high prevalence of obesity and physical inactivity in the U.S. is a public health crisis. This study aims to examine the effects of high-intensity functional training (HIFT) on exercise perceptions and physiological changes in inactive females. A pre-test and post-test, quasi-experimental design was conducted with inactive, middle-aged females (n = 8) participating in an 8-week supervised and verified intervention (2-week High-Intensity Interval Training, 6-weeks HIFT). The Health Belief Model Scale for Exercise (HBMS-E) survey was completed pre-intervention, post-intervention, and 4-week follow-up to assess exercise perceptions. Pre- and post-intervention physiological assessments …

Emotional Overeating And Eating Motives During Covid-19 In Polish Women: Intergroup Comparison Among Participants In Various Body Mass Index Categories, Adriana Modrzejewska, Justyna Modrzejewska, Kamila Czepczor-Bernat, Julia Wyszomirska

Baltic Journal of Health and Physical Activity

Introduction: Taking into account the situation of the COVID-19 pandemic and the ac-companying lockdown resulting in increased negative emotions, it is interesting to learn about eating motives and behaviors and check their intensity. The aim of this study was to investigate the differences between Polish women in various body mass index categories in terms of eating motives and emotional overeating during the COVID-19 pandemic. Material and methods: This study sample comprised 1,447 women (M_age = 31.34 ± 11.05; M_BMI = 23.79 ± 4.59). The research used the following tools: the Eating Motivation Survey, the Emotional Overeating Questionnaire, and …

The Parthenon, September 25, 2024, Evan Green, Sarah Davis, Baylee Parsons, Joseph Dicristofaro, Kaitlyn Fleming, Scott Price, Abigail Cutlip, Rafael Alfonso, Wade Sullivan

The Parthenon

No abstract provided.

Genome-Wide Identification, Phylogeny, And Pharmacological Analysis Of Date Palm Cyclic Nucleotide-Gated Ion Channel (Cngc) Gene Family In Response To Fungi, Mumtaz Ali̇ Saand, Marina Memon, Ameer Ahmed Mi̇rbahar, Qurban Ali̇ Magsi, Athar Abbas Babar, Sahib Abbas Ghanghro

Turkish Journal of Botany

Cyclic nucleotide-gated ion channel (CNGC) is one of the important calcium conducting channels and involves in numerous biological functions such as plant development, phytohormone responses, plant-pathogen interactions. Nevertheless, identification of CNGC gene family has yet not been carried out in date palm crop. In this study, genome-wide identification, and pharmacological analysis of date CNGCs was conducted against fungal pathogens. The 26 PdCNGC genes were identified by using extensive bioinformatics tools. Gene ontology (GO) analysis showed that signal transduction, transmembrane transport and ion binding proteins were at the top in biological process and molecular functions of PdCNGCs. Protein-protein interaction of PdCNGCs …

Professor Uses Stem To Help Solve Food Security In Mississippi, Clara Turnage

University of Mississippi News

OXFORD, Miss. – David H. Holben has spent most of the last decade educating children in north Mississippi using food, gardens and nutrition. Now, his work and others' are being recognized by the White House.

Gamma-Aminobutyric Acid Induction Of Triticale Protective Systems Under Drought, Salt Stress Or A Combination Of The Two, Yuriy Kolupaev, Ivan V. Shakhov, Alexander I. Kokorev, Liana I. Relina, Alla I. Dyachenko, Alexander P. Dmitriev

Turkish Journal of Botany

Gamma-aminobutyric acid (GABA) is currently considered to be an important stress metabolite with regulatory functions in plants. Exogenous GABA is known to be able to enhance the tolerance of different plant species to drought and salt stress. However, its effects on the functioning of stress-protective systems in triticale, an intergeneric wheat-rye hybrid with specific adaptation strategies to abiotic stresses, remained completely unstudied. We studied the effects of exogenous GABA (0.5 mM) on the growth as well as on the antioxidant and osmoprotective systems of triticale seedlings (cv. 'Rarytet') under simulated drought (15% PEG 6000), salt stress (100 mM NaCl), or …

A New Species Of Nigrospora (Apiosporaceae) In Corylus Heterophylla In China, Jing Wang, Zhong-Xuan Liu, Wei Yu, Chao Kang, Yi Hua Yang

Turkish Journal of Botany

Corylus heterophylla, the majestic hazelnut tree, stands as one of the esteemed quartet of grand nuts reigning across the landscapes of temperate Asia, Europe, and North America. But its relationship with endophytic fungi remains thinly explored. This study successfully identified a new species designated as Nigrospora coryli through conjoint analysis of morphology and systematics. The genetic regions examined encompassed ITS, TUB2, and TEF1-α.The detailed morphological description, colour photographs of Macro- and microcharacters are presented.

Nutrition Management In Children Less Than 5 Years Of Age With Glycogen Storage Disease Type I: Survey Results, Mary Sowa, Monica Boyer, Jessica Green, Surekha Pendyal, Heather Saavedra

Faculty, Staff and Student Publications

Background: Nutrition management for GSD Type I (GSDI; OMIM #232200, 232220) is complex, with the goal being to maintain euglycemia while minimizing metabolic derangements. Management guidelines were published in 2002 and 2014. However, there is limited information on the nuances of nutrition management and the unique feeding challenges of children.

Methods: A REDCap survey focusing on staffing and current practices in the nutrition management of children with GSD I who were < 5 years of age was sent to the metabolic dietitian's listserv and GMDI membership in 8/2023.

Results: There were 21 North American respondents. In 17/21 clinics (81%), Prosobee® was the primary choice for infant formula. Dietitians used different methods to determine hourly glucose needs. Fasting …