Digital Commons Network^™

Injectable, In Situ Forming Peptide Nanofiber Reinforced Composite Hydrogels For Age-Related Macular Degeneration, Shambhavi Bagewadi Ms

Theses and Dissertations

Cell therapy for age-related macular degeneration (AMD) is limited by the absence of a functional substrate such as Bruch’s membrane (BM), which is critical for retinal pigment epithelial (RPE) cell survival and integration. Although preformed substrates have been explored, their implantation can disrupt the fragile retinal architecture, compromise ocular immune privilege and increase infection risk. To address these limitations, an injectable hydrogel capable of forming in situ was developed. The hydrogel consists of thiol-modified hyaluronic acid (HA-SH) and polyvinyl alcohol (PVA). Peptide nanofibers were incorporated to enhance structural reinforcement. Three self-assembling peptides - RADA-16, GAGA and GAGA-YIGSR were designed and …

Running Gait Kinematics Are Reproducible At The Beginning And End Of Two Different Intensity, Energy Expenditure Matched Runs, Using Either Discrete Points Or Functional Data Analysis, Sherveen Riazati, Nick Caplan, Philip R. Hayes

Faculty Research, Scholarly, and Creative Activity

Introduction – The aims of this study were to examine reliability of treadmill running kinematics: i) during two different intensity, energy expenditure matched, runs ii) at two time points within each run iii) using two different methods of statistical analysis. Methods – Twenty healthy club distance runners performed two high intensity interval runs (HIIT) and two medium intensity continuous runs (MICR). Kinematics during ground contact were analysed in all three planes of motion at the ankle, knee, and hip. Maximum angle and range of motion were identified and for Functional Data Analysis (FDA) all of the collected data was utilised. …

Women Self-Help Groups As Drivers Of Community Development In Rural Kenya, James Kariuki, Bhoke Chacha

Journal of Global Awareness

Self-Help Groups (SHGs) are informal grassroots associations of people who have similar objectives and concerns working cooperatively and collectively to meet their needs and improve their living conditions. SHGs are known to contribute towards the development and welfare of their members. This paper examines the role of SHGs in community development in Kenya with a focus on selected women groups in Migori and Makueni Counties. The study adopted a mixed research approach that provided both qualitative and quantitative data, and it was anchored on two interrelated theories of community development: empowerment theory and social capital theory. The researchers interviewed 80 …

Caring For The Carers: Exploring The Mental Wellbeing Of Informal Palliative Caregivers Of Cancer Patients In Kenya, James Kariuki, Rose Njiraini

Journal of Global Awareness

Cancer cases have been on the increase globally, and this has led to economic burden on the affected households. One way of reducing the cost of care is through home-based care by informal palliative caregivers who include family members, friends, and other people assigned by the family members to take care of the patient. The objectives of this study were to assess the status of the mental wellbeing of palliative caregivers of cancer patients; to examine the relationship between the ability of the patient to cope with cancer diagnosis and the mental wellbeing of the caregiver; and to investigate the …

Exploring The Role Of Magnesium Deficiency In Inflammatory Bowel Disease, Victor A. Bob-Yellowe, Shaunte Hadnot, Sonya Bhatia, Anesu K. Murambadoro

MEDI 9331 Scholarly Activities Clinical Years

Inflammatory Bowel Disease (IBD) is a group of chronic gastrointestinal disorders, including Ulcerative Colitis and Crohn’s disease. As of 2020, it was estimated that IBD significantly impacts the lives of approximately 2.39 million Americans. Magnesium (Mg) is an essential mineral involved in many bodily functions, including immune response and gut health. Recent studies suggest that Magnesium levels may be linked to IBD. Therefore, this review aims to explain how Magnesium might play a role in the development or progression of IBD. Additionally, this article discusses the overall role that Magnesium’s plays in gut health and whether Magnesium supplementation could be …

Effects Of Warming On Growth And Leaf Colonization By Litter Mat-Forming Fungi In A Wet Tropical Forest In Puerto Rico, Ari E. Puentes, D. Jean Lodge, Deyaneira A. Ortiz-Iglesias, Tatiana Barreto-Vélez, Laura C. Rubio-Lebrón, Hieu Chu, Christine S. O'Connell, Sasha C. Reed, Tana E. Wood

Biology, Chemistry, and Environmental Sciences Faculty Articles and Research

Wet tropical forests are experiencing rising temperatures and increased frequency and intensity of extreme climatic events, such as cyclones, which can increase rates of soil erosion and surface runoff. Fungal litter mats, formed by agaric decomposer fungi, play a crucial role in stabilizing slopes, preventing erosion, and aiding nutrient cycling; however, little is known about how warming affects litter mat growth and function. We investigated two litter mat-forming fungi, Gymnopus johnstonii and Marasmius aff. crinis-equi, in warmed (+4°C above ambient) and control plots in the Luquillo Experimental Forest, Puerto Rico. Growth and time-to-leaf colonization were monitored over 6 weeks …

Improving Nursing Compliance With Pressure Injury Prevention In Postoperative Patients In The Cardiovascular Intensive Care Unit, Chingyi Lam

Doctor of Nursing Practice Final Project Abstract

Pressure injuries acquired in the hospital continue to be a major concern in patient safety among critically ill populations. The purpose of the quality improvement project was to improve nursing compliance with pressure injury prevention strategies among postoperative patients in a cardiovascular intensive care unit (CVICU). Patients who undergo cardiovascular surgery are at a high risk of developing pressure injuries due to immobility, sedation, vasopressors, and prolonged positioning on their backs. The quality improvement project was carried out in a 37-bed CVICU using the Institute for Healthcare Improvement (IHI) Model for Improvement and Plan–Do–Study–Act (PDSA) cycles. Data on nursing repositioning …

The Red Hook Community Court: A Continuing Experiment, Christopher Slobogin

NULR Online

No abstract provided.

Examining The Ligands, Location, And Function Of Toll-Like Receptor 10, Kiefer Keanu Tam

Master's Theses

Toll-like receptors are a class of innate immune pattern recognition receptors that detect pathogen-associated molecular patterns and regulate downstream inflammatory responses. Toll-like receptor 10 remains the only human TLR whose ligand specificity, cellular localization, and immunological function are not fully defined. Emerging evidence suggests that TLR10 may play an anti-inflammatory role and can heterodimerize with TLR2 to modulate immune signaling. Previous studies from our laboratory demonstrated that stimulation with heat-killed Mycobacterium tuberculosis promotes TLR2-TLR10 heterodimerization and trafficking to the cell surface. In this study, we expanded our ligand panel to include additional gram-positive bacteria, particularly anti-inflammatory probiotic species, to further …

Herd Conditions And Food Security: Evidence From Kenya, Kira J. Enriquez

Master's Theses

Food insecurity is worsening across Kenya's Arid and Semi-Arid Lands, where over three million people currently face acute hunger. Among pastoral communities in these regions, livestock are the central productive asset and primary food source. When herds deteriorate, households face falling milk production and the erosion of assets that would otherwise buffer consumption during difficult periods. This paper tests whether livestock body condition and rangeland forage quality predict household food coping behavior, and whether those relationships differ above and below a Micawber-style herd size threshold. Using a panel of 232 pastoralist households surveyed across five ASAL counties between 2021 and …

Linking Fishery Productivity To Child Health In The Coastal Tropics, Francisco Flores-Mejia

Master's Theses

Fish are a primary source of calories, macronutrients, and income for coastal communities around the world, but overfishing and environmental changes have dramatically reduced productivity in the majority of small-scale fisheries. The social costs of these losses are believed to be large, particularly in poorer communities, but most estimates of fishery productivity effects on households are contextual and difficult to generalize. We combine a remote sensing measure of pelagic fishery productivity with geolocated child health and growth data from 34 countries in the coastal tropics. We estimate that the difference between sustainedly good versus bad fishing conditions corresponds up to …

Spatial Analysis Of Maize Yields And Household Dietary Diversity In Sub-Saharan Africa: Causal Evidence From A Machine Learning Instrument, Addi Joof

Master's Theses

MAIZE YIELDS AND HOUSEHOLD DIETARY DIVERSITY IN SUB-SAHARAN AFRICA: EVIDENCE ON THE CAUSAL EFFECT FROM A MACHINE LEARNING INSTRUMENT

Addi Joof, University of San Francisco, May 2026

This paper provides estimates of the effect of maize yield on household dietary diversity across seven Sub-Saharan African countries, using data from 36,474 maize-growing households in the Living Standards Measurement Study Integrated Surveys on Agriculture (LSMS-ISA) panels for the period 2008--2021. OLS estimates which include district and country-by-wave fixed effects yield a positive and significant coefficient of 0.070 (SE = 0.006, p < 0.001), implying that a 10 percent increase in maize yield raises the Household Dietary Diversity Score (HDDS) by approximately 0.007 food groups. Because self-reported yields are subject to classical measurement error and unobserved household characteristics confound the OLS estimate, we construct an instrumental variable using a Random Forest model trained on satellite-derived agro-environmental features including the Enhanced Vegetation Index, Normalized Difference Vegetation Index, Growing Degree Days, precipitation, and soil moisture obtained from Google Earth Engine at the GPS-coordinate-by-year level. Our preferred 2SLS specification, which adds region fixed effects to absorb persistent sub-national geographic variation, returns a positive point estimate of 0.217 (SE = 0.206; 95% CI: -0.19 to +0.63, p = 0.294) larger than OLS and consistent with downward attenuation bias, but imprecisely estimated and statistically indistinguishable from zero at conventional levels. We interpret the OLS estimate of 0.070 as a credible lower bound on the true effect, with the IV evidence pointing to a moderately larger but uncertain magnitude. Heterogeneity analysis reveals a declining gradient across consumption quintiles the effect is strongest among the poorest households (Q1: 0.055, p < 0.01) and diminishes with wealth (Q5: 0.015, not significant) while showing no gradient across market-integration levels. These patterns are consistent with own-consumption, rather than market income from surplus sales, as the primary pathway from yield to dietary diversity. OLS estimates are positive and significant in five of six estimable countries. The findings suggest that maize yield improvements can serve as a nutrition co-investment, particularly for subsistence-oriented smallholders, though the available data do not permit a sharp causal quantification of the effect size.

Keywords: dietary diversity, maize yields, instrumental variables, Sub-Saharan Africa, LSMS-ISA, satellite …

Updated Trends In The Global Prevalence And Burden Of Mental Disorders, 1990–2023: A Systematic Analysis For The Global Burden Of Disease Study 2023, Damian F. Santomauro, Paul Anthony Miller, Jamileh Shadid, Sarah Wulf Hanson, Anh Vo, Darius Jake Roy, Hailey Hagins, Ana M. Mantilla Herrera, James G. Scott, Holly E. Erskine, John J. Mcgrath, Hasan Aalruz, Hedayat Abbastabar, Nadin M.I. Abdel Razeq, Ahmed Abdelrahman Abdelgalil, Ali Abdolizadeh, Deldar Morad Abdulah, Abisola Esther Abdulmalik, Meklit Girma Abebe, Mesfin Abebe, Habtamu Abebe Getahun, Roberto Ariel Abeldaño Zuñiga, Olifan Zewdie Abil, Richard Gyan Aboagye, Shady Abohashem, Abdullahi Tunde Aborode, Moaz Elsayed Abouelmagd, Mohammad T. Abuawwad

All Works

Background The 2023 iteration of the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) estimated prevalence, incidence, and health burden for 375 diseases and injuries, including 12 mental disorders. We assess past, current, and emerging trends in the prevalence and burden of mental disorders across sexes and age groups, for 21 regions, 204 countries and territories, and by Socio-demographic Index (SDI) quintile, from 1990 to 2023. Methods Mental disorders included in GBD 2023 were anxiety disorders, major depressive disorder, dysthymia, bipolar disorder, schizophrenia, autism spectrum disorders, conduct disorder, attention-deficit hyperactivity disorder, anorexia nervosa, bulimia nervosa, idiopathic developmental intellectual …

Soil Dna-Phosphorus: Method Optimisation And Application Across Uk Soils, Margaret Massam, Daniel Menezes-Blackburn, Mohammed Al Kasbi, Catherine Wearing, Marc Stutter, Courtney D. Giles, Tegan Darch, Timothy S. George, Charles Shand, David Lumsdon, Martin Blackwell, Hao Zhang, Patricia Cooper, Renate Wendler, Lawrie Brown, Philip M. Haygarth

Journal of Agricultural and Marine Sciences

Despite growing recognition of rapid diester P turnover, quantitative data on soil DNA-P across soil types remain scarce due to methodological constraints. This study aimed to investigate the impact of changes in the analytical protocol of a soil DNA-P method developed by Paraskova et al. (2013) on DNA-P recovery and the use of the revised procedure on 32 UK soils on our understanding of DNA-P in soils. The steps of the Paraskova method were tested on two contrasting soils, and a revised version was developed and used to determine the DNA-P levels of 32 UK soils. These findings were then …

Effects Of Combined Application Of Biochar And Nitrogen Fertilizer On The Growth Parameters Of Lemongrass (Cymbopogon Citratus), Ashkan Asgari, Yunes Rameshjan, Babak Jamali, Aminallah Tahmasebi

Journal of Agricultural and Marine Sciences

The synergistic application of biochar and nitrogen fertilizer significantly improves plant growth and soil properties. The present study aimed to evaluate the effect of the application of biochar and nitrogen on the shoot and root of lemongrass in a factorial design within a completely randomized setup. The experiment included three levels of biochar, i.e. 0%, 1%, and 2% (v/v) and 2 levels of nitrogen, i.e. 0 and 1 (g/pot) under greenhouse conditions with 3 replications. The following parameters were measured, plant height, number of tillers, number of leaves, length of the largest leaf, fresh, shoot and root dry weight. The …

Utilizing Artificial Neural Networks (Ann) To Forecast Date Palm Exports And The Regulatory Period Of The United Arab Emirates, Almouthana Aziz Hasan, Ibrahim Mohammad Abdullah

Journal of Agricultural and Marine Sciences

The research aimed to forecast the exports of United Arab Emirate (UAE) from date palm during the period (2021-2030). The R programming language was used to conduct econometric analysis in artificial intelligence, by analyzing time series of the factors influencing the UAE date palm export quantity and using the (ARIMA) methodology and construction of the artificial neural network (ANN). The results demonstrated that the influence of independent factors on the quantity of future exports was apparent, including the UAE date palm production quantity in tons (x1) at a percentage of (21.08%), domestic consumption in tons (x2) by (20.69%), mean UAE …

Kicau Kericau: The Chirps And Warbles Of A Bird-Human Story, Airien Ludin

Masters Theses

This thesis tells the tale of bird-human relationships and what it means to live alongside one another, subverting the hierarchical view of humans as above birds inherited from colonial history. It asks how the practice of illustration can function as a site of Two-Eyed Seeing, where scientific and local knowledge are held together as an entangled narrative. It also examines how mendongeng (storytelling), as I have experienced it within Indonesian culture and everyday contexts, can help us understand birds as a companion species with their own agency.

This project takes two forms: first, a picture book titled Sun Bird …

Psychological Strain And Infrastructure Deficit And The Decision To Migrate Among Healthcare Workers From Lagos, Nigeria, Fatima Adeboye

Walden Dissertations and Doctoral Studies

No abstract provided.

Staff Education To Emergency Department Professional Nurses, Florence Chukwuneke Chukwuneke

Walden Dissertations and Doctoral Studies

No abstract provided.

The Parent Phone Use Regulation Efficacy Scale (P-Pure): Initial Validation And Associations With Problematic Smartphone Use, Self-Regulation, Impulsivity, Mindfulness, And Self-Efficacy, Brandon T. Mcdaniel, Sabrina Uva, Adam M. Galovan

Health Services and Informatics Research

Parents often rely on smartphones in daily life. While smartphones offer benefits, they also present challenges, such as potential distraction and delayed responsiveness. It is also possible that problematic smartphone habits may develop, such as repeated checking or difficulty controlling use. Furthermore, self-efficacy around regulating one’s phone use is tied to the ability to change, meaning self-efficacy could be a key mechanism impacting the effectiveness of interventions regarding problematic phone use. Thus, we developed and explored the validity of the Parent Phone Use Regulation Efficacy Scale (P-PURE) to assess parents’ self-efficacy in managing phone use around their children. We developed …

Slouching Towards Inefficiency? The Cardiometabolic And Cognitive Costs Of Poor Posture, Ava Mae Fitzenrider

Honors Projects

Posture affects all of our lives. It is both static and dynamic, adapting continuously to environmental demands. One postural alteration frequently observed in occupational settings is hyperkyphosis, which can be induced by sitting position. During computer use, individuals commonly adopt a slouched posture, which can exacerbate hyperkyphosis, and contribute to dis-ease within the body. Previous research has demonstrated that such postural deviations can negatively affect pulmonary function, as well as other bodily functions. Despite these findings, the effects of acute hyperkyphosis (“slouching”) on cardiometabolic function and cognition remain largely unexplored. Therefore, the purpose of this study was to examine the …

Advancing School-Based Sexual Reproductive Health Education Through A Fifth-Grade Educator Toolkit, Emira Romero

Doctor of Nursing Practice (DNP) Projects

Background: Although sexual and reproductive health (SRH) education is a critical component of early health literacy and health promotion, educators remain underprepared to deliver this education. Local Problem: A gap analysis conducted at School A, a public elementary school in the San Francisco Bay Area, revealed the absence of a SRH curriculum for their fifth graders. Methods: A Doctor of Nursing Practice (DNP) student-led quality improvement project to introduce a SRH educator toolkit to increase educator confidence and self-efficacy was conducted at School A among fifth grade teachers. Pre- and post-intervention data were collected on implementation day to evaluate the …

Perceptions Of Pregnant And Early Postpartum Women On Maternal Mortality, Virginia Queen Edochie

Walden Dissertations and Doctoral Studies

No abstract provided.

Household Hegemon: Domestic And Affective Traces Of Us Influence In Mexico In The 1950s And 1990s, Edgar Solórzano

Masters Theses

“Household Hegemon: Domestic and Affective Traces of US Influence in Mexico in the 1950s and 1990s” is a collection of personal essays, historical research, and fictional texts that examine the impact of US-American soft power on Mexican society. This project expands and deepens the research and work developed during my two-year MFA in Sculpture at RISD, evolving material investigations into a comprehensive written and visual record of the 1950s post-WWII boom and the 1990s post-NAFTA transition. These two decades not only represent the most significant in terms of American influence but also the years in which my parents and I …

Another Palace For The People, Kate Holbrook

Masters Theses

Coined the “Palace for the People,” the American public library was established as a free, democratic haven for the public’s literary and educational needs. Adapting to the changing needs of its patrons, the public library’s services have extended beyond book access to provided services ranging from tool rentals to warming centers, postal services, and more. As both an essential landmark of the physical city through its exterior and provider of social infrastructure on its interior, public libraries seek sustainable avenues to continue their tradition of gathering, idea exchange, and provision. Expanding upon the identity of the public library as a …

Resistant Silence Engraved Trauma, Silence In Domestic Spaces, & Acts Of Resistance, Priyanka Kumar

Masters Theses

This thesis argues that silence surrounding trauma within domestic spaces is not merely an absence of speech or a condition of voicelessness, but it functions as an act of resistance. Focusing on domestic abuse within patriarchal structures, this research examines the ways trauma is embodied, negotiated, and concealed in everyday life. Central in this inquiry is the figure of the “sole witness” to abuse, those who live in close proximity to violence, endure its aftermath and negotiate survival through subtle and often unseen acts of resistance.

I am not attempting to define trauma, but the thesis explores the traces trauma …

Soft Power, Arab Media And Sports Mega Events: Coverage Of Fifa 2022 And Lessons For Future Arab Hosting, Lynne Kennedy, Maaira Shahbaz, Ala Al Rajabi

All Works

Sport mega-events (SMEs) increasingly transcend athletic competition, functioning as strategic instruments for national identity formation, statecraft, and soft power projection. This dynamic is particularly pronounced in the Gulf, where Qatar’s successful hosting reignited regional rivalries and attracted unprecedented global scrutiny. While existing scholars have extensively examined Western media portrayals of SMEs, a notable gap remains for academic engagement with Gulf media. Dismissed as state-controlled and analytically lacking, we contend that such media offer a rich site for exploring how small states use media as soft power, to construct and contest legitimacy, identity, and global influence. This analysis suggests how state-aligned …

Muscle Changes In Critically Ill Children Following An Early Progressive Exercise In The Paediatric Intensive Care Unit: A Pre- And Post-Intervention Study, Shaodan Qi, Yuxia Yang, Jing Hu, Weijie Shen, Hao Zhou, Jos M. Latour, Weiming Chen, Ying Gu

School of Nursing and Midwifery

Background: Most critically ill children in the paediatric intensive care unit (PICU) are immobilised. Prolonged immobilisation in the PICU negatively affects children's physical health outcomes. Aim: The aim of the study was to evaluate the effectiveness of an early progressive exercise (EPE) intervention to improve the PICU-acquired muscle weakness and to assess the safety of the EPE intervention. Study Design: A single-centre pre- and post-intervention design was adopted. The intervention was the EPE starting within 48–72 h after PICU admission. Primary outcome was the 7-day difference of right rectus femoris muscle cross-sectional area (RRMCSA). Secondary outcomes were the 7-day difference …

Holistic Management Of Epilepsy In Adults With Intellectual Development Disorders, Elena Fonseca, Antonella Riva, Samuel López‐Maza, Malin Zaddach, Marie‐Claire Porter, Ingo Borggraefe, Lance Watkins, Andreas Schulze‐Bonhage, Rohit Shankar, Pasquale Striano, Lina Nashef

Peninsula Medical School

This seminar addresses the complexity of the management of epilepsy in adults with intellectual development disorders (IDD), advocating holistic and multidisciplinary care aligned with the learning objectives of the International League Against Epilepsy. Epilepsy is significantly more prevalent in people with IDD, presenting unique diagnostic, therapeutic, and psychosocial challenges. Accurate diagnosis is hampered by limitations in communication, necessitating reliance on caregivers' observations. In adults with IDD and epilepsy, utilization of diagnostic tools, e.g., video electroencephalograph (EEG) monitoring, is helpful but can be challenging. Management requires careful consideration of cognitive and behavioral comorbidities and the effects of antiseizure medications (ASMs) on …

Member Spotlight- Dr. Julian Metts Quietly Making A Difference, Frank P. Iuorno Jr., Dds

Virginia Dental Journal

No abstract provided.