Digital Commons Network^™

The Life And Discoveries Of Yellapragada Subbarow, Nikhil R, Varuni Pragya, Subramanian Ramaswamy, Shiva Prasad B N, Mahabaleshwar Mamadapur

Digital Journal of Clinical Medicine

Dr. Yellapragada Subbarow was a researcher, teacher, and a wizard of wonder drugs who constantly made efforts in the discoveries/ inventions such as vitamins, anti-vitamins, antibiotics, and many more by disentangling the mysteries of nature for the betterment of the people. He inspired the youngsters to take up the challenges and to stand up above mediocrity. The reward for his achievement was delayed. The article describes a true humanist's journey, discoveries, and his achievements that are largely unknown to date.

Advancing Theory In Psychographic Market Segmentation Research, Jack A. Lesser, Suanne M. Barthol

Journal of Applied Marketing Theory

For decades, marketing research has focused on identifying psychographic segments to develop corporate strategy. However, as this article contends, psychographic segmentation research has often lacked sufficient theoretical grounding, particularly in the selection of variables and underlying theories guiding these studies. To address this gap, the present study systematically reviews a broad range of segmentation studies to evaluate their theoretical contributions and identify promising directions for future research. The analysis begins by examining the theories in a comprehensive psychographic segmentation study by Lesser and Hughes (1986a), followed by a review of 38 additional studies to uncover relevant underlying theories. The study …

Understanding Global Street Food Consumer Behavior And Experience: A Narrative Review Of Literature And Development Of Framework, Samit Chakravorti

Journal of Applied Marketing Theory

This paper explores global street food consumer behavior and consumption experience. The aim of this paper is to gain a holistic comprehension of street food consumption decision making and experience through exploring nature and sources of perceptions, attitude and expectations surrounding street food, the characteristics of the product offering and the domain within which it is served and consumed. To achieve this aim the author engages in a narrative review of academic research on consumer behavior of street food, provides a holistic picture of consumption experience of street food through consolidating and interpreting research findings, and extends the theoretical understanding …

Elevation And Population Size Effects On The Survival Of Drosera Rotundifolia, Jessica Williams

Electronic Theses and Dissertations

Carnivorous plants face significant conservation challenges due to habitat destruction, climate change, and illegal harvesting. This study explores how elevation and population size influence key-life history traits of D. rotundifolia, such as flowering phenology, prey capture efficiency, seed production, and germination rates. Higher elevations and larger populations are associated with extended flowering durations and increased prey capture. However, seed production and germination rates show complex patterns that are likely influenced by genetic diversity, resource availability, or environmental conditions. These insights inform targeted conservation strategies, emphasizing habitat preservation, enhancing prey availability, and maintaining genetic diversity. Public education and community engagement …

Three Decades Of Rat Genomics: Approaching The Finish(Ed) Line, Theodore S Kalbfleisch, Melissa L Smith, Julia L Ciosek, Kai Li, Peter A Doris

The Brown Foundation: Institute of Molecular Medicine

The rat, Rattus norvegicus, has provided an important model for investigation of a range of characteristics of biomedical importance. Here we survey the origins of this species, its introduction into laboratory research, and the emergence of genetic and genomic methods that utilize this model organism. Genomic studies have yielded important progress and provided new insight into several biologically important traits. However, some studies have been impeded by the lack of a complete and accurate reference genome for this species. New sequencing and genome assembly methods applied to the rat have resulted in a new reference genome assembly, GRCr8, which …

Identification Of Proteins Associated With Type 2 Diabetes Risk In Diverse Racial And Ethnic Populations, Shuai Liu, Jingjing Zhu, Hua Zhong, Chong Wu, Haoran Xue, Burcu F Darst, Xiuqing Guo, Peter Durda, Russell P Tracy, Yongmei Liu, W Craig Johnson, Kent D Taylor, Ani W Manichaikul, Mark O Goodarzi, Robert E Gerszten, Clary B Clish, Yii-Der Ida Chen, Heather Highland, Christopher A Haiman, Christopher R Gignoux, Leslie Lange, David V Conti, Laura M Raffield, Lynne Wilkens, Loïc Le Marchand, Kari E North, Kristin L Young, Ruth J Loos, Steve Buyske, Tara Matise, Ulrike Peters, Charles Kooperberg, Alexander P Reiner, Bing Yu, Eric Boerwinkle, Quan Sun, Mary R Rooney, Justin B Echouffo-Tcheugui, Martha L Daviglus, Qibin Qi, Nicholas Mancuso, Changwei Li, Youping Deng, Alisa Manning, James B Meigs, Stephen S Rich, Jerome I Rotter, Lang Wu

Faculty, Staff and Student Publications

Aims/hypothesis: Several studies have reported associations between specific proteins and type 2 diabetes risk in European populations. To better understand the role played by proteins in type 2 diabetes aetiology across diverse populations, we conducted a large proteome-wide association study using genetic instruments across four racial and ethnic groups: African; Asian; Hispanic/Latino; and European.

Methods: Genome and plasma proteome data from the Multi-Ethnic Study of Atherosclerosis (MESA) study involving 182 African, 69 Asian, 284 Hispanic/Latino and 409 European individuals residing in the USA were used to establish protein prediction models by using potentially associated cis- and trans-SNPs. The models were …

December 2024, Swosu Bulldog Wellness Committee

SWOSU BULLDOG WELLNESS

December is Healthy Eating Month

• Eating a variety of foods, including vegetables, fruits, and whole-grain products
• Eating lean meats, poultry, fish, beans, and low-fat dairy products
• Getting enough fiber
• Drinking lots of water
• Limiting salt, added sugars, alcohol, and saturated fat
• Making sure that you get enough nutrients, especially calcium, vitamin D, and potassium

Effectiveness Of Enhanced Care For Treatment Of Acute Or Persistent Diarrhea In Malnourished Children Aged 0 Months To 10 Years: A Systematic Review, Ridwa Alam, Khadija Vadsaria, Ahmad Khan, Uswa Jiwani, Aqsa Ishaq, Anmol Minaz, Ashraf Sharif, Jai K. Das, Sajid Bashir Soofi, Shabina Ariff

Centre of Excellence in Women and Child Health

Background: Diarrhea poses a significant public health challenge, particularly affecting children under five. The link between malnutrition and diarrhea is well established, with diarrhea being a primary cause of malnutrition in young children and malnutrition exacerbating the severity of diarrhea. While the World Health Organization (WHO) recommends a comprehensive approach to both diarrhea and malnutrition management, including oral rehydration, continuous feeding, zinc supplementation, and antibiotics for specific strains, it does not adequately address the complex needs of malnourished children with diarrhea who may benefit from enhanced care in the form of follow-up and monitoring beyond initial treatment. We aimed to …

2024 Rc Ac, Greg Jordan

Advisory Council

No abstract provided.

The Practical Adoption And Application Of Blockchain Technology Within The Beverage Industry, Alexander Adams Jr

Electronic Theses, Projects, and Dissertations

Abstract

The beverage industry is facing heightened scrutiny as the demand for transparency and accountability reaches new heights. In the age of information technology, companies must prioritize enhanced traceability to ensure product safety, comply with government regulations, maintain customer trust, and protect brand integrity. This thesis explores the potential of blockchain technology as a solution to these challenges, focusing on its ability to decentralize data, improve traceability, and expedite response times during safety recalls. The research provides an overview of the evolution of food safety regulations, beginning with the first establishment by Upland Sinclair, and examines current traceability practices and …

The Impact Of Mindfulness On Student Engagement: During And After The Covid-19 Global Pandemic, Michelle Mendiola

Electronic Theses, Projects, and Dissertations

This qualitative study explored the lived experiences of educational leaders who incorporated mindfulness practices (MFP) student engagement (SE) in their classrooms during and after the COVID-19 global pandemic, utilizing hermeneutic phenomenology and bracketing as research methodologies. The study aimed to understand how these leaders' use of mindfulness impacted student engagement in both online and in-person learning environments. Drawing on semi-structured qualitative interviews, the research examined how mindfulness practices were adapted in response to the unique challenges posed by remote education during the pandemic and how these adaptations have persisted or evolved in post-pandemic teaching. Key findings reveal that mindfulness not …

Nutraceutical Supplement Mitigates Insulin Resistance In Horses With A History Of Insulin Dysregulation During A Challenge With A High-Starch Diet, Caroline Loos, Annette Castelein, Eric Vanzant, Emma Adam, Kyle R. Mcleod

Animal and Food Sciences Faculty Publications

Insulin dysregulation (ID) is associated with an increased risk of laminitis which often necessitates the need for clinical intervention. To test the contention that the prophylactic supplementation of nutraceuticals could mitigate ID in susceptible horses, 16 mature horses with a history of ID were supplemented with either the placebo (n = 8) or nutraceutical (n = 8) once daily. Horses were housed in dry lots with ad libitum access to grass hay and fed a concentrate twice daily to provide 0.5 g starch/kg BW/meal. A combined glucose–insulin tolerance test was performed on all horses before and after 4 weeks of …

Investigating The Link Between Over-The-Counter Pain Medication Use And Hypertension Risk, Maheen Zahidi, Saira Saeed Khan, Sadaf Naeem, Anosh Tahir, Gufran Ullah Khan, Maryam Mehmood, Afshan Bano

The Thai Journal of Pharmaceutical Sciences

Background: Non-steroidal anti-inflammatory drugs (NSAIDs), both non-selective and selective cyclooxygenase-2 (COX-2) inhibitors, are among the most widely prescribed drugs worldwide. NSAIDs alter renal function if given in high enough doses, reducing renal blood flow and the glomerular filtration rate and causing sodium retention. An issue of interest is the association between the consumption of self-medicated over-the-counter (OTC) drugs analgesics, specifically NSAIDs and hypertension (HTN), which is considered as a cardiovascular risk factor. Objectives: This research aims to establish the relationship between the frequent use of OTC NSAIDs and an increased risk of hypertensive disease, emphasizing the implications of …

Addressing The Teen Mom Situation In Thailand: A Systematic Review On Challenges, Initiatives And Recommendations For Improvement, Junkkrit Wunggrath, Phinphot Phrommasen, Wanchalerm Ritthimon

Jurnal Keperawatan Indonesia

Teenage pregnancy in Thailand poses significant public health challenges with implications for societal welfare and economic development. This systematic review analyzed the challenges faced by teenage mothers in Thailand, evaluated existing initiatives, and proposed evidence-based recommendations. A comprehensive literature search was conducted using the Scopus and Web of Science databases and others focusing on literature from 2016 to 2023. Keywords included “teenage pregnancy,” “teen mom,” “unwanted pregnancy,” and “unintended pregnancy” resulting in the selection of 36 studies. The PRISMA framework was followed to ensure a systematic approach. Data extraction focused on societal, educational, economic, and health-related challenges as well as …

Hungry Again, Casey Gao, Special Collections, Fleet Library

11th Baker & Whitehill Student Artists' Book Contest 2025

Entry for the 11th Baker & Whitehill Student Artists' Book Contest. Opening reception and award ceremony Wednesday, February 19, 2025 at 6:30pm, Fleet Library, Main Reading Room. Juror: Roger S. Williams.

Obstructive Sleep Apnea And Obesity: How Weight Loss Improves Sleep Apnea Severity And Quality Of Life - An Integrative Review, Hannah Wilson, Neda Akbarshahi

Master's Projects

Introduction: With the growing prevalence of OSA due to the obesity epidemic, there is an urgent need to update treatment regimens. While CPAP continues to be the gold standard of OSA care, challenges with adherence and limited access to effective weight management strategies often impede care. The complex bidirectional relationship between obesity and OSA highlights the importance of addressing weight management in this patient population to help mitigate cardiometabolic risks. Personalized weight loss therapies should be integrated into standard OSA treatment regimens to reduce OSA severity, reduce comorbid conditions, and improve quality of life.

Aim: The objective of this integrative …

Victory Gardens: Helping On The Home Front, A Curriculum Outreach Project, Kelly Hoomes

Master's Theses

The Victory Garden: Helping on the Homefront traveling trunk outreach project links past, present, and future by introducing students to the historical significance of World War II victory gardens and emphasizing the continued relevance today. Partnering with Kennesaw State University’s Museum of History and Holocaust Education (MHHE), the traveling trunk focuses on a fifth-grade audience, aligning with Georgia Standards of Excellence for Social Studies, Health, and Science. The traveling trunk designed as a “museum-in-a-box" includes primary sources, artifacts, and a practical gardening activity that fosters critical thinking and analysis. By encouraging an understanding of the past and the connections to …

The Relationship Between Chute Behavior And Morbidity In Cattle, Andrea Rankin

Animal Science Undergraduate Honors Theses

Most cattle see a handling chute at least once in their lives. Handling plays a huge role in cattle management, whether it’s for transportation, auction sales, deworming, medical treatments, or AI purposes. Morbidity related to Bovine Respiratory Disease (BRD) is one of the biggest causes of economic loss for ranchers and can be related to handling stress. Auction-derived calves (ADC; n=92) were brought to the University of Arkansas Savoy Research Facility for processing and monitoring for behavioral cues and disease. The objective of this study was to find a relationship between the calves’ behavior in the chute and morbidity. The …

Foster Care, Substance Use, And Social Determinants Of Health In South Carolina: A Geographic Approach, Patricia Carbajales-Dale

All Dissertations

Foster care is a critical intervention for vulnerable children, with approximately 400,000 children entering the system annually in the United States. Parental substance use, second only to neglect, is now a leading cause of foster care entry. While previous research has explored the relationship between socioeconomic factors and foster care, few studies have incorporated spatial approaches at the neighborhood level to understand how factors such as economic inequality, healthcare disparities, and substance use influence foster care entries. This study addresses that gap by integrating spatial analysis and machine learning techniques to examine the geographic and social dynamics underlying foster care …

Advancing Substance Use Disorder Treatment Using Genomics And Metabolomics, Lindsey Contella

All Dissertations

Advancing our understanding of genetic, metabolic, and environmental factors in substance use disorder (SUD) could lead to more effective therapies. In 2022, 16.5% of the U.S. population was diagnosed with SUD, yet current treatments lack efficacy for all patients, making a precision medicine approach crucial. This dissertation explores SUD's relationship with tryptophan (TRP) metabolism through the kynurenine pathway (KP) as a potential therapeutic target. Chapter I reviews current knowledge on SUD and KP. Chapter II identifies how SUD alters KP metabolite concentrations, identifying a reduced concentration of the neuroprotective metabolite, kynurenic acid (KA) and elevated concentrations of the neurotoxic metabolite, …

Insights Into Malaria Vectors–Plant Interaction In A Dryland Ecosystem, Fiona Kinya, Trizah K. Milugo, Clifford M. Mutero, Charles S. Wondji, Baldwyn Torto, David P. Tchouassi

All Peer-Reviewed Publications

Improved understanding of mosquito–plant feeding interactions can reveal insights into the ecological dynamics of pathogen transmission. In wild malaria vectors Anopheles gambiae s.l. and An. funestus group surveyed in selected dryland ecosystems of Kenya, we found a low level of plant feeding (2.8%) using biochemical cold anthrone test but uncovered 14-fold (41%) higher rate via DNA barcoding targeting the chloroplast rbcL gene. Plasmodium falciparum positivity was associated with either reduced or increased total sugar levels and varied by mosquito species. Gut analysis revealed the mosquitoes to frequently feed on acacia plants (~ 89%) (mainly Vachellia tortilis) in the family Fabaceae. …

Promoting Adolescent Mental And Physical Health: Initiatives Focused On Connecting Public Health And Social Services To The Health Sector In Nebraska, Theresa Nguyen

Capstone Experience: Master of Public Health

This capstone focuses on the second recommendation of improving access to comprehensive, coordinated health services from the National Academies of Sciences, Engineering, and Medicine report The Promise of Adolescence: Realizing Opportunity for All Youth (2019). This proposal uses secondary data from the research project, Moving Evidence-Based Recommendations to Practice to Strengthen the Health Care System in Nebraska. Key stakeholders (n=28) were interviewed from the health care, public health, social services, and policy sectors. Each subject was asked to participate in a semi-structured interview by a trained interviewer. The interview was 1 hour long and conducted via phone call or Zoom. …

Closing Gaps To Address Lifespan Health: Considerations For Developing A Preconception Healthcare Training For Community Health Workers, Jaclyn R. Vancamp

Capstone Experience: Master of Public Health

Community health workers (CHWs) are frontline public health workers who are embedded in their own communities and as linkages to care, decreasing health disparities for underserved individuals. The goal of this capstone project was to identify Michigan CHWs' knowledge gaps in the area of preconception healthcare. Through administering a training needs assessment to a sample of community health workers, the goal was to characterize knowledge gaps and make recommendations about what type of training would be most useful to them. The results of this needs assessment showed that the general state of self-reported knowledge about preconcept health among Michigan community …

Understanding And Mitigating The Potential Effects Of Postpartum Depression On Fathers And Male Support Persons, Rachel Norton-Turk

Capstone Experience: Master of Public Health

Background. During the postpartum period, best practices dictate that medical professionals screen new mothers or birthing persons for anxiety and depression and direct them to the appropriate resources and services they may need. This qualitative study explored the steps being taken to identify depression and anxiety concerns in male support partners during the postpartum period and to understand what resources are being brought to their attention if depression and anxiety are identified. Methods. A convenience sample of male support persons participated in semi-structured, one-on-one interviews either in-person or over Zoom between September and October 2024. Interviews were recorded, transcribed, …

Roger Williams University 2024 President's Report: A Message From President Miaoulis, Roger Williams University

Life of the Law School (1993- )

No abstract provided.

Assessing The Influence Of Native And Invasive Grasses On The Behavior Of Aedes Aegypti In South Texas, Emily Medelez

Theses and Dissertations

Invasive grasses in South Texas can have widespread negative effects, displacing native species, reducing biodiversity, and posing risks to public health. These grasses may flourish in moist, shaded environments, which not only support their growth but also creates habitats favorable for mosquito activity. This can increase the population and alter the behavior of mosquitoes, potentially raising the risk of disease transmission. In this thesis, I look at the behavior of mosquito species Aedes aegypti, primary vector of the yellow fever virus. I analyzed the influence of oviposition, flight and resting behaviors. I tested the relative attraction of Aedes mosquitoes …

Using High-Pressure Processing To Improve The Quality Of Dark-Cutting Beef, Ashley A. Hahn

Department of Animal Science: Dissertations, Theses, and Student Research

Previous studies have shown high-pressure processing (HPP) can be utilized to improve lean color of dark-cutting beef color by increasing the lightness and redness of steaks. However, the optimal parameters of length of time product is held under pressure and at which pressure must be applied have yet to be fully defined. Furthermore, the impact of HPP on color labile muscles in dark-cutting beef are currently unknown. Therefore, two studies were designed and specific efforts were focused on first defining optimal parameters for color stable muscles, followed by determining the effect of HPP on dark-cutting color labile muscles.

In the …

Examining Factors Of Variance In Energy Metabolism Of Dairy Cattle, Addison L. Carroll

Department of Animal Science: Dissertations, Theses, and Student Research

Variation is thought to occur in the use of dietary energy for production in dairy cattle. First, variance can be observed when new methane mitigation strategies are fed resulting in increased H₂ output potentially resulting in downstream effects on estimates of heat production via the Brouwer (1965) equation. Therefore, in chapter 3 a review was created to systematically describe the mathematics and theory behind the Brouwer equation, and rederive a heat production equation to integrate H₂ production. Results indicate heat production using the classical Brouwer equation (1965) relative to the rederived equation resulted in an overestimation of heat …

Impacts Of Annual Forage Management On Grazing Cattle Performance And Carrying Capacity, Shelby Davies Jenkins

Department of Animal Science: Dissertations, Theses, and Student Research

Rapid conversion of historical grasslands to cropland in recent history has led to limited perennial pasture availability and an increase in cost of pasture rent. Annual forages are an alternative grazing source. Many annual forages can grow and accumulate stockpile following summer harvest of wheat. Strip grazing is often suggested to increase grazing efficiency of stockpiled forages. To evaluate this, a stockpiled mixture of annual forages were either strip grazed or grazed continuously in the fall and winter. The mixture contained oats and rapeseed in the first year and a diverse warm season annual mixture in the second. Strip grazing …

Pathway-Based Clustering Identifies Two Subtypes Of Cancer-Associated Fibroblasts Associated With Distinct Molecular And Clinical Features In Pancreatic Ductal Carcinoma, Hongjing Ai, Rongfang Nie, Xiaosheng Wang

Faculty, Staff and Student Publications

Existing single-cell clustering methods are based on gene expressions that are susceptible to dropout events in single-cell RNA sequencing (scRNA-seq) data. To overcome this limitation, we proposed a pathway-based clustering method for single cells (scPathClus). scPathClus first transforms single-cell gene expression matrix into pathway enrichment matrix and generates its latent feature matrix. Based on the latent feature matrix, scPathClus clusters single cells using the method of community detection. Applying scPathClus to PDAC scRNA-seq datasets, we identified two types of cancer-associated fibroblasts (CAFs), termed csCAFs and gapCAFs, which highly expressed complement system and gap junction-related pathways, respectively. Spatial transcriptome analysis revealed …