Digital Commons Network^™

The World Bank's New Approach To Human Capital Model And Education, Ozlem Kucuk, Cihan Cobanoglu

University of South Florida (USF) M3 Publishing

The human capital approach, introduced in 1960, has been used by economists to establish connections between education, skills, and personal income. It resulted in a redistribution of public expenditure by viewing education not only as a cost but also as an economic input, a way to increase revenue in the medium and long term. Human capital theory highlights the crucial role of education in the economy. With the rise of the knowledge society, scientists have debated the potential end of poverty, inequality, and social exclusion. They envisioned a new knowledge economy and a more egalitarian society. The significant increase in …

Design And Synthesis Of Therapeutic Molecules Targeted At Metabolic Pathways Of Cancer And Lipid Signaling In Fungal Diseases, Jennifer Uzoamaka Nnaemeka

All Theses

Cancer remains a leading cause of global mortality, with 20 million new cases and 9.7 million deaths recorded in 2022 (WHO, 2024). While advancements like nanoparticles and monoclonal antibodies offer new treatments, they often cause severe toxicity to normal cells. This study introduced novel thiamin-based compounds targeting enzymes critical for cancer cell proliferation. These compounds were synthesized via a three-step process involving tosylation, SN2 coupling with phenolic compounds, and subsequent reactions to form thiamin-like-phenol derivatives. Yields ranged from 50-70%, and Nuclear Magnetic Resonance (NMR) confirmed their structures. Anticancer activity was assessed by the National Cancer Institute. Separately, drug-resistant fungal infections, …

Soybean Cyst Nematode (Heterodera Glycines Ichinohe) Virulence Assay Against Resistance Sources In Nebraska, Pratibha Karki

Department of Plant Pathology: Dissertations, Theses, and Student Research

Soybean cyst nematode (SCN, Heterodera glycines Ichinohe), one of the major yield-limiting pathogens of soybean, is currently found in 60 counties of Nebraska that produce more than 90% of the state’s soybean. Often, yield loss occurs without any above-ground symptoms, which makes it difficult to manage. The primary management option is the use of SCN-resistant varieties. Several soybean plant introductions serve as resistance sources against SCN. Unfortunately, the single source, PI 88788, is used in approximately 90% of resistant varieties and its prolonged use has increased the virulence status of SCN in the U.S. A study was conducted to assess …

Taking A Closer Look At Tpack: Examining Teacher Perspectives Of The Knowledge, Competencies, And Context Needed For Improved Remote Education In Grades 4-8, Jennifer Christine Buth Bell

Dissertations and Doctoral Documents, University of Nebraska-Lincoln, 2023–

Though wrought with challenges, the COVID-19 Pandemic, which led to the closure of schools worldwide and forced educators into a rapid transition from traditional to Emergency Remote Teaching (ERT), held some promise for furthering the integration of digital technology in schools. But now, years following the crisis, policymakers, administrators, and teachers continue to grapple with how best to incorporate lessons learned and improve the future of teaching and learning in both traditional and remote settings. This mixed-methods study (n = 21; n = 6) followed an explanatory sequential design to collect and analyze data from a sample of 4th-8th …

Characterization Of The Final Enzyme In The Coenzyme M Biosynthesis Pathway In Methanosarcina, Connor John Hines

Dissertations and Doctoral Documents, University of Nebraska-Lincoln, 2023–

Methanogenesis is known to be one of the oldest forms of energy generation on our planet. Methanogens rely on this method of energy conservation and have evolved to metabolize a variety of substrates, including the waste products of other organisms. This feature has made methanogens beneficial to both wastewater treatment and landfill-to-energy projects. Methane itself is a greenhouse gas twenty times more potent than carbon dioxide, viewed as a particularly influential contributor to global greenhouse emissions. Climate change was known to be on the horizon throughout the 20^th century but has made itself known vocally during this 21^{st …}

The Endocrine And Body Composition Responses To Accentuated Eccentric Loading Performed In Cluster Sets During A Strength–Endurance Training Block, Kurt W. Mcdowell, Alex Long, Daniel Gahreman, D. Andrew Nelson, Nicholas J. Goode, Ryan P. Lis, Sungwon Chae, Satoshi Mizuguchi, Marten Baur, Kevin F. Breuel, Marco Duca, John P. Wagle, Andy C. Fry, Michael H. Stone

Kinesiology

Featured Application: Research on the endocrine changes from AEL training is limited, especially for long-term effects. This study suggests that combining AEL with CS might offer similar or slightly better results compared to traditional training. However, the practical challenges, such as increased training monotony and strain, may outweigh the minimal benefits. The extra cost, time, and effort required for AEL, especially in large team settings, might not be justified. Additionally, individual differences in optimal loading prescriptions could complicate its use, making traditional methods more efficient. This study investigated the endocrine responses to accentuated eccentric loading (AEL) paired with cluster sets …

Addressing The Public Health Concern Of Maternal Mortality In Houston, Texas, Lucy Couture

Dissertations and Theses (Open Access)

Maternal mortality remains a pressing public health concern in the United States, with disproportionate consequences for marginalized communities. Despite being a developed nation, the U.S. reports one of the highest maternal mortality rates among its peers, with approximately 80% of maternal deaths deemed preventable. Texas reflects this national crisis, particularly affecting Black women, whose maternal mortality rate is significantly higher than that of other racial and ethnic groups. This thesis explores maternal mortality trends in Houston, Texas, analyzing the roles of systemic inequities, social determinants of health, and disparities in access to quality care. Drawing on data from the Texas …

The Role Of Midwives In Achieving The Global Sustainable Development Goals, Bakhtawar Muhammad Hanif Khowaja Bk, Elizabeth K. Darling

Journal of Asian Midwives (JAM)

The sustainable development goals (SDGs) provide a comprehensive framework for global development. Midwives are playing an important role in achieving the targets of the world’s priority agendas. They are actively involved in achieving the targets of SDG#2 by providing education to women on their nutritional requirements, supporting postnatal women with breastfeeding, and educating communities on the use of clean water, sanitation, and hygiene management. Beyond counseling and educating communities on nutrition and hygiene management, they are also involved in improving other health-related outcomes that are indicators for SDG#3, such as improving maternal and child immunization, counseling mothers on tobacco …

Factors Influencing Colostrum Avoidance In Developing Countries: Insights From A Literature Review, Muhammad Zeeshan Aslam, Jonathan Johnson, Marina Baig, Abeer Musaddique

Journal of Asian Midwives (JAM)

Introduction: Colostrum is a thick, sticky, clear and yellowish-coloured milk produced after the first few hours of birth until day 3. It consists of vitamin A, proteins, lipids, potassium, and maternal antibodies, including lactoferrin, immunoglobulin, growth factors and antimicrobial factors. Colostrum avoidance is the practice of squeezing out, pumping, and discarding the first milk. Various studies have reported colostrum avoidance worldwide, but its prevalence is higher in developing countries. Every day, approximately 3000 to 4000 infants die due to diarrhea and respiratory infections in developing countries, and one of the leading causes is colostrum avoidance. Infants are unable to take …

Improve The Referral System Of Health Care Organizations In Rural Community Settings Of Pakistan Using Health Information Technology (Hit) - A Protocol, Saleema A. Gulzar, Alishah Aziz Gulzar, Zahid Ali Faheem, Ayesha Arif, Aamir Sarfaraz

Journal of Asian Midwives (JAM)

Pakistan is a developing country, with 65% of the population residing in rural areas. The rural population is considered vulnerable mainly due to several factors, including poverty. Climate change and the area's topography limit their access to basic human needs such as basic healthcare, affecting their quality of life. Most people lack basic information about the location and availability of healthcare facilities, including hospitals, diagnostic centres, pharmacies, and general clinics. Hence, the rural healthcare system lacks primary care physicians, nurses, midwives and allied health professionals. Inappropriate infrastructure makes it challenging to retain qualified professionals. A non-profit and non-governmental entity aims …

Pakistan Ischemic Stroke Guidelines, Anjum Farooq, Maria Khan, Ayesha Zafar, Husnain Hashim, Fozan Khan, Abdul Malik, Ayeesha Kamran Kamal Aga Khan University, Karachi, Mohammad Wasay

Pakistan Journal of Neurological Sciences (PJNS)

Stroke is the second leading cause of death and disability. Mortality related to stroke is very high in low- and middle-income countries. Stroke imposes a great socioeconomical burden in Pakistan. It is important to take important steps for prevention and proper management of stroke in country. Purpose of developing stroke guidelines is to improve stroke care in Pakistan. Guidelines are designed to help neurologists and general practitioners for treating stroke. American stroke guidelines, NICE guidelines, Canadian guidelines and multiple important articles including those emphasizing stroke care in low- and middle-income countries were studied, and these current guidelines were designed in …

Bad Plants, Heather I. Sullivan

Modern Languages and Literatures Faculty Research

“Bad plants” represent the seemingly unexpected and startling forms of plant power overlooked by many modern, industrialized societies that treat vegetal beings as mere resources instead of animate, world-shaping forces. Since science fiction and fairy tales often explore more openly animistic visions of non-human life, such texts provide ample possibilities for reconsideration by critical plant studies of our human-plant relations both cultural and ecological. For example, both Jack McDevitt’s 2001 science fiction novel, Deepsix, and Ludwig Tieck’s 1799 fairy tale, “Faithful Eckart and Tannhäuser”, feature “bad plants” that bring human beings violently back into the plant cycles they assume they …

Magnetic Resonance Imaging Trackable Pathology-Triggered Polymersomes Toward Enzyme Replacement Theranostics For Gm1 Gangliosidosis, Dorian Foster

All Dissertations

This dissertation investigates the development and optimization of pathology-responsive polymersomes for simultaneous enhanced magnetic resonance imaging (MRI) and enzyme replacement therapy (ERT) in the treatment of GM1 gangliosidosis (GM1). While therapeutic strategies exist for similar, non-neuropathic lysosomal storage disorders, implementation towards GM1 faces significant challenges due to the blood-brain barrier.

Herein, we developed and characterized a range of low molecular weight hyaluronic acid-b-polylactic acid (HA-PLA) polymersomes (PSs) capable of encapsulating therapeutic enzymes in their hydrophilic core. These polymersomes exhibit pathophysiology-triggered responsiveness, degrading in the presence of acidic conditions, which is characteristic of lysosomes, and enzymes such as hexosaminidase A, which …

Responding To The Workforce Crisis: Consensus Recommendations From The Second Workforce Summit Of The American Society Of Pediatric Nephrology., Danielle E. Soranno, Sandra Amaral, Isa Ashoor, Meredith A. Atkinson, Gina-Marie Barletta, Michael C. Braun, Joann Carlson, Caitlin Carter, Annabelle Chua, Vikas R. Dharnidharka, Keri Drake, Elif Erkan, Dan Feig, Stuart L. Goldstein, David Hains, Lyndsay A. Harshman, Elizabeth Ingulli, Alexander J. Kula, Mary Leonard, Sudha Mannemuddhu, Shina Menon, Zubin J. Modi, Marva Moxey-Mims, Arwa Nada, Victoria Norwood, Michelle C. Starr, Priya S. Verghese, Darcy K. Weidemann, Adam Weinstein, Jodi Smith

Manuscripts, Articles, Book Chapters and Other Papers

IMPORTANCE: Pediatric patients with complex medical problems benefit from pediatric sub-specialty care; however, a significant proportion of children live greater than 80 mi. away from pediatric sub-specialty care.

OBJECTIVE: To identify current knowledge gaps and outline concrete next steps to make progress on issues that have persistently challenged the pediatric nephrology workforce.

EVIDENCE REVIEW: Workforce Summit 2.0 employed the round table format and methodology for consensus building using adapted Delphi principles. Content domains were identified via input from the ASPN Workforce Committee, the ASPN's 2023 Strategic Plan survey, the ASPN's Pediatric Nephrology Division Directors survey, and ongoing feedback from ASPN …

Azacitidine As Epigenetic Priming For Chemotherapy Is Safe And Well-Tolerated In Infants With Newly Diagnosed Kmt2a-Rearranged Acute Lymphoblastic Leukemia: Children's Oncology Group Trial Aall15p1, Erin M. Guest, John A Kairalla, Meenakshi Devidas, Emily Hibbitts, Andrew J. Carroll, Nyla A. Heerema, Holly R. Kubaney, Margaret A. August, Sidharth Ramesh, Byunggil Yoo, Midhat S. Farooqi, Melinda G. Pauly, Daniel S. Wechsler, Rodney R. Miles, Joel M. Reid, Cynthia D. Kihei, Lia Gore, Elizabeth A. Raetz, Stephen P. Hunger, Mignon L. Loh, Patrick A. Brown

Manuscripts, Articles, Book Chapters and Other Papers

Infants less than 1 year old diagnosed with KMT2A-rearranged (KMT2A-r) acute lymphoblastic leukemia (ALL) are at high risk of failure to achieve remission, relapse, and death due to leukemia, despite intensive therapies. Infant KMT2A-r ALL blasts are characterized by DNA hypermethylation. Epigenetic priming with DNA methyltransferase inhibitors increases the cytotoxicity of chemotherapy in preclinical studies. The Children's Oncology Group trial AALL15P1 tested the safety and tolerability of 5 days of azacitidine treatment immediately prior to the start of chemotherapy on day 6, in four post-induction chemotherapy courses for infants with newly diagnosed KMT2A-r ALL. The treatment was well-tolerated, with only …

Guidelines On Management Of Hereditary Polyposis Syndromes In Pediatric Patients: Agreement, Disagreement And Where It Matters, Taina Hudson, Claudia Phen, Isabel Rojas, Shlomi Cohen, Warren Hyer, Thomas M. Attard

Manuscripts, Articles, Book Chapters and Other Papers

Hereditary polyposis syndromes are rare but potentially devastating conditions which require multidisciplinary care from an early age. Societal guidelines, which ideally combine expert opinions and medical evidence, serve as the framework for disease diagnosis, surveillance and treatment. However, there is a significant underrepresentation of pediatric gastroenterology input in guideline formulation, and additionally, recommendations can vary significantly between societies, which can have a moderate-to-high clinical impact on patient care. This paper aims to summarize key differences in management based on societal guidelines and identify some of the factors which may contribute to divergence in care in hereditary polyposis syndromes in pediatric …

Advocating For More Personalized And Evidence-Based Approaches In Dental Practice, Integrating Advanced Diagnostic Tools And Innovative Treatments To Enhance Patient Care, Hasanuddin, Acing H. Mude, Muhammad Ikbal, Erni Marlina, Muhammad Ruslin

Journal of Dentomaxillofacial Science

This editorial review highlights a series of studies emphasizing evident discoveries in the diagnosis and treatment of oral diseases. The first report addresses a rare case of unicystic ameloblastoma located in the maxillary sinus, highlighting the need of histological analysis for precise identification despite deceptive radiographic characteristics. A different example examines dentigerous cysts, highlighting diagnostic problems stemming from unusual appearances, finally clarified by histological assessment. The effectiveness of sclerotherapy with hypertonic saline for treating parotid sialocele is examined, indicating it as a safe and efficacious therapeutic alternative. The influence of anemia on pediatric drug-induced erythema multiforme is examined, highlighting the …

Adverse Childhood Experiences And Early Life Adversity And Their Effects On Chronic Health: A Literature Review, Ella Weatherford

The Eleanor Mann School of Nursing Undergraduate Honors Theses

With more than 439,000 annual U.S. deaths associated with childhood adversity, it is important to understand and prevent exposure to Adverse Childhood Events and Early Life Adversity. The purpose of this literature review is to identify and examine the pathophysiology between adverse childhood experiences (ACE’s) and their negative effects on health across the lifespan. Fifteen peer-reviewed articles that were published in notable journals were analyzed to include in this review. The results of these articles show that Adverse Childhood Experiences and Early Life Adversity can lead to the development of chronic inflammatory conditions across the lifespan. Using Barker Hypothesis and …

Characterizing The Usda-Npgs Germplasm Collection Of Tartary Buckwheat (Fagopyrum Tataricum), Noah Joseph Abasciano

Master's Theses and Capstones

AbstractTartary buckwheat (Fagopyrum tataricum) is a promising underutilized crop in the context of New England’s rapidly changing environment (USDA NH State Profile, 2022). Despite substantive prior work on the genetics and nutrition of Tartary buckwheat (Zhang et al., 2017b), many practical questions pertaining to its potential cultivation in New England remain unanswered. This thesis presents the first systematic genotypic and phenotypic screening of the USDA National Plant Germplasm System's (NPGS) Tartary buckwheat germplasm collection in an effort to lay the foundations for future crop improvement efforts. The genotypic assessment of the NPGS Tartary buckwheat germplasm was completed by first bottlenecking …

The Impact Of Hospital Protocol For Severe Alcohol Use Disorder, Meredith Jones

The Eleanor Mann School of Nursing Undergraduate Honors Theses

Background: Alcohol use disorder remains a prevalent condition within current society. For a smaller, but ever growing population, alcohol use evolves into a severe, addictive disease process. Individuals managing this disorder can suffer from acute withdrawals and further comorbidities causing eventual detriment. Medical institutions attempt to combat withdrawal with varying forms of treatment, utilized to manage symptoms and further issues “as needed.” As this condition becomes increasingly more pervasive within casual society, hospitals’ fragmented attempts to manage this disease process proves to be ineffective for this patient population.

Purpose: The purpose of this systematic review is to analyze current methods …

The Show Must Go On: Leading Factors In The Burnout Of Stage Managers, Morgen E. Doyle

Honors College Theses

Stage managers are the key to making theatre move onstage and in the audience. To keep the show, we need to take care of our stage managers. Many have voiced concerns about burnout from their time in the stage management industry (McGraw 2024, 12). Burnout can be defined as “a syndrome conceptualized as resulting from chronic workplace stress that has not been successfully managed” and characterized by three main dimensions: “energy depletion and exhaustion; feelings of cynicism and increased mental distance related to the individual’s job; and reduced professional efficiency in the individual’s workplace” (World Health Organization 2019). In this …

Assessing General Propulsion Architectures For Fast Transit Times To Mars For Crewed Missions, Vivek Bhatt

Doctoral Dissertations and Master's Theses

As NASA and commercial contractors, such as SpaceX, continue to develop their programs with Artemis and Starship, respectively, it is becoming more and more apparent that the program developments are ultimately for finding a way to put humans onto Mars. However, when we approach the current timeline of going to Mars, it usually involves a 6-9 month one way trip. Due to this, human spaceflight to Mars becomes more dangerous as exposure to affects such as solar radiation, long exposure to low gravity fields, and isolation. These are some of the many hazards that come with interplanetary space travel for …

Integrated Transcriptomics And Proteomics Study Of Starvation Selected Drosophila Melanogaster, Aavash Adhikari

UNLV Theses, Dissertations, Professional Papers, and Capstones

Drosophila melanogaster, selected for starvation resistance exhibits phenotypic traits such as increased body size, slower development, reduced fecundity and obesity like characteristics including higher lipid reserves and cardiac dysfunction. While prior studies have explored the metabolic and biochemical changes in these flies, the underlying genetic and molecular mechanisms remain unclear. This study aims to investigate the gene expression and protein abundance in starvation-selected Drosophila through RNAseq, proteomics, and integrating both datasets using the MixOmics package in R. I found differential gene expression in the fat body at the third instar larval stage, particularly in pathways related to lipid metabolism, calcium …

Biological Reduction Of Mixed Oxyanions In Wastewater Brine, Katherine J. Earp

UNLV Theses, Dissertations, Professional Papers, and Capstones

Treatment of contaminated brine water is an area of active research spurred by the use of advanced treatment technologies, such as membrane separation, reverse osmosis, ion exchange, etc. for water reuse and recycling, which has become critical due to the impact of climate change on water resources throughout the globe. Biological reduction of harmful organic and inorganic pollutants in water has been demonstrated as an effective method for water and wastewater treatment and would be a potential technology for brine treatment. However, biodegradation of contaminants in high salinity waters is challenging because most microbial communities cannot survive brine environments. The …

Understanding Levels Of Perceived Racism And Discrimination When Utilizing Perinatal Care, Alexandria S. Evans

UNLV Theses, Dissertations, Professional Papers, and Capstones

Social and structural determinants of health, grounded in historical racism and discrimination, significantly influence maternal health outcomes. Because of this, communities of color experience a higher burden of maternal health disparities. In the last several decades, there has been an increased awareness of the need to integrate critical race theory into public health research to address maternal health disparities in the context of perinatal care delivery, policy, and funding decisions.

This three-manuscript dissertation utilized mixed methods to examine the ways in which systemic racism and discrimination are perceived and how it impacts the utilization of perinatal care services in historically …

Self-Regulated Learning Through Self-Concordant Goals, Social Modeling And Sustainability Focus, Oana Mandrutiu-Iancu

UNLV Theses, Dissertations, Professional Papers, and Capstones

Research has shown that when students spend time reflecting and autonomously selecting their college goals, they show high intrinsic motivation, low extrinsic motivation and improvement in emotional and social adjustment over the first several months of college. Despite of this, it is estimated that 77% of first- and second-year students are undecided on their major and many remain undecided as they transition into their junior and senior year. Moreover, in education settings the primary emphasis is on academic success, but focusing solely on academic goals is limiting. As learning is inherently social, academic and social domains cannot be separated, while …

Chronic Illness Education 2024: Tackling Childhood Obesity Using The Chronic Care Model, Avan Chu, Bassem Chamma, Katiya Barkho, Ryan Li, Sabrina Pakula, Zoe Raphael

Patient Education Projects

No abstract provided.

Chronic Illness Education 2024: Educational Resources For Families To Improve Childhood Obesity, Arianna Arcenas, Colton Clymer, Henry Li, Jonathan Albrecht, Kathleen Girdler, Saleh Ahmed

Patient Education Projects

No abstract provided.

Potential Ethanol Extracts Of Super Red Dragon Fruit Peel And Flesh For Detecting Dental Plaque, Euis R. Yuslianti, Dewi Li. Nasution, Nadya S. Pramita

Journal of Dentomaxillofacial Science

Objective: Dental plaque is a collection of microorganisms that adhere to surface of tooth and can cause various health problems in oral cavity. To detect plaque on surface of teeth, a coloring agent such as a disclosing solution is needed. As an alternative ingredient that does not harm, this study used super red dragon fruit peel and flesh (Hylocereus costaricensis) which is high levels of anthocyanins and natural coloring agents that can be used as alternative materials for detecting plaque on surface of tooth.

Material and Methods: The research methode were quasi-experimental design research with a post-test control …

Assessing The Impact Of An Individual Diabetic Education Program And Big Data App On Three Generations Of Patient Populations, Avery C. Carpenter, Rechendia C. Carpenter, Ester M. Felipe

Doctoral Projects

Diabetes is a chronic condition that affects numerous people worldwide. Diabetic education assists people with understanding the nature of diabetes, its side effects and how to successfully deal with the condition. The doctoral project incorporates finding out how glucose monitoring, prescription administration, dieting propensities, and the significance of customary activities. With proper education the impact on one’s health with this chronic condition can improve for the better.

The nature of this doctoral project is to assess the impact that a diabetic education program and big data app have on three generations. Members of the group partnered with Hutton Healthcare in …