Digital Commons Network^™

Beyond The Latch: Supporting Maternal Health During Breastfeeding, Emmanuela Nwaonumah, Amenah Qotineh, Hadeer Hegazy, Logan Cowan, Joanne Chopak-Foss

Eagles Talking About the Public’s Health

No abstract provided.

Homeschooling And Online Learning Technologies From A Parent’S Perspective, Karla M. Forti

Theses and Dissertations

The purpose of this quantitative, predictive correlational research study was to examine the relationship between homeschooling parents’ use of educational technology tools and their instructional behaviors and perceptions, with additional consideration of virtual school participation. Survey-based data from 22 parents of over 40 homeschooled children were used to examine technology adoption and instructional preferences across non-traditional learning settings. The study addressed four research questions through descriptive statistics and correlational analysis, while quantitative themes from open-ended responses enriched the findings. Results provided insight into parental motivations and trends influencing homeschooling and virtual school choices, highlighting the expanding role of online learning …

Molecular Chaperones At The Host-Virus Interface: Heat Shock Protein Roles In Hiv-1 And Emerging Insights For Hiv-2 And Dual Infection, Sabastine Eugene Arthur, Kirk Klogo, Emmanuel Kobina Mensah, Maame Ama Pentsiwa Cudjoe, Adomia Baaba Mensah, Nyamekye Amoabeng Ankrah, Catherine Laaripuoh Omosule, Evelyn Yayra Bonney, George Boateng Kyei

2020-Current year OA Pubs

Heat shock proteins (HSPs) are essential molecular chaperones involved in protein folding, cellular stress responses, and homeostasis. Recent studies reveal their critical and dual roles in the human immunodeficiency virus (HIV) life cycle, both promoting and restricting viral replication, latency, and immune modulation. This review synthesizes current evidence on how key HSP families, HSP70, HSP90, and HSP40, interact with HIV proteins such as Tat, Rev, Nef, and Vpx, affecting viral transcription, protein trafficking, and latency. We also highlight Heat Shock Factor 1 (HSF1) as a direct regulator of the HIV-1 long terminal repeat (LTR), facilitating latency reversal via recruitment of …

Assessing The Efficacy Of The Natural Disaccharide Trehalose In Ameliorating Diet-Induced Obesity And Metabolic Dysfunction, Yu-Sheng Yeh, Trent D Evans, Se-Jin Jeong, Ziyang Liu, Ali Ajam, Carlos Cosme, Jun Huang, Doureradjou Peroumal, Xiangyu Zhang, Ali Javaheri, Jaehyung Cho, Irfan J Lodhi, Babak Razani

2020-Current year OA Pubs

Trehalose is a naturally occurring disaccharide with versatile commercial applications and health benefits, including promise as a therapeutic for obesity and diabetes. Although numerous previous reports purport the therapeutic uses of orally ingested trehalose, the abundance of glycosidases in the gastrointestinal tract suggest the potential for significant limitations of oral trehalose that have not been addressed. We first fed mice a high-fat diet (HFD) while providing trehalose by both oral and intraperitoneal routes. This combined strategy was broadly efficacious in reversing HFD-induced weight gain, fat mass, insulin resistance, and the development of hepatosteatosis. In contrast, oral-only trehalose failed to improve …

Big Cells, Big Impact: Unravelling Seasonal Patterns Of Net Primary Production In Narragansett Bay, Dominique Jae Lockwood

Open Access Master's Theses

Net primary production is a measurement of available energy, or the amount of biomass that phytoplankton produce during photosynthesis that fuels marine food webs and drives carbon cycling. Despite its ecological importance, net primary production is relatively understudied in comparison to chlorophyll-a, which is often used as a proxy for biomass rather than productivity. In this study, we measured size-fractionated net primary production and chlorophyll-a concentrations in Narragansett Bay over a 14-month period from January 2022 to February 2023. Weekly surface water samples were collected and filtered to distinguish between small (> 10 μm) and large ( …

Associations Between Dietary Sodium And Potassium Intakes, Urinary Sodium And Potassium Excretion And Blood Pressure Among Adult Females In Oromia Region, Ethiopia, Fred Baffour Addo

Open Access Master's Theses

Introduction: Accurate assessment of sodium (Na) and potassium (K) intake is essential for population level monitoring of salt intake as part of global strategies to reduce salt consumption to control the increasing prevalence of high blood pressure (BP). Thus, a simple, cost-effective, and low-burden method is particularly valuable in resource-limited settings for population level monitoring of Na and K intake. This study aimed to compare the reliability of various methods of Na and K intake assessment, and their associations with blood pressure measurements.

Methods: This secondary analysis was based on a cross-sectional study of 100 non-pregnant women of …

Exosomes: Historical Evolution And Emerging Roles In Dermatology, Nina Schur, Luna Samman, Milaan Shah, Victoria Dukharan, Carol Stegura, Luke Broughton, Todd Schlesinger

GME Publications

Background: Exosomes are a nanoscale extracellular vesicles derived from different cell types that have been investigated for various clinical applications, including functioning as biomarkers and use as direct therapeutics. Given the role of exosomes in multiple pathophysiologic pathways and potential practical applications, they have garnered significant interest in the scientific community but much is still unknown about their development and use.

Aims: This literature review covers the background, mechanisms of action, use as biomarkers, methods of application, and direct therapeutic applications of exosomes.

Methods: A literature review on the background and uses of exosomes was conducted. Key articles describing the …

Rice Plants Response To Modulation Of The Erecta Signaling, Yasmin Vasques Berchembrock, Flavia Barbos Silva Botelho, Bhuvan Pathak, Shan Zhao, Vibha Srivastava

Crop, Soil and Environmental Sciences Faculty Publications and Presentations

The ERECTA family of receptors (ERfs), encoding leucine-rich repeat receptor-like kinases (LRR-RLKs), can regulate multiple aspects of plant development and abiotic stress responses. The rice (Oryza sativa) genome contains three ERfs, namely ERECTA 1 (OsER1), ERECTA 2 (OsER2), and ERECTA-LIKE (OsERL). However, there is limited information currently available on their expression pattern during the plant developmental stages. The expression pattern of OsERfs genes at reproductive stages from the booting (R2) to milk (R6) stage in Nipponbare cultivar and the transgenic plants expressing a truncated Arabidopsis ERECTA (ER) lacking the kinase domain (triangle Kinase) were studied. The triangle Kinase functions as …

Utah Farmers Markets: Statewide Social And Economic Impacts, Bryn Watkins, Jaclyn Pace, Steven Price, Roslynn Mccann

All Current Publications

Utah is home to over 45 markets where local farmers and artisans sell their homegrown food and homemade wares. These markets gather community, stimulate regional commerce, champion nutrition for Utahns from all backgrounds, and most of all, create a home for local agriculture to flourish.

Continuous Quality Improvement In Social Needs Screening: Evaluation Of An Intervention In Bariatric Specialty Care, Claire Chang, Samantha Cooley, Bradley Iott, Jordan Greene, Dilhara Muthukuda, Renuka Tipirneni

Student Publications

_{Introduction:}

With growing recognition of the influence that social risks, such as food insecurity and housing instability, have on individual and population health, social risk screening and social care interventions have proliferated across the health system. Social needs intervention research on screening and referral in specialty care is limited, despite evidence that social needs influence access to and outcomes of surgical and specialty care.

_Methods:

This study is a qualitative, formative evaluation of a quality improvement-oriented social needs screening and referral pilot program implemented in a bariatric surgery practice and aims to share lessons related to the structure and process …

Designing A Logbook To Enhance Pedagogical Effectiveness In Public Health Internships In Morocco, Fadila Bousgheiri, Zaynab Mahdi, Faïza Charif, Karima Sammoud, Hicham El Bouri, Adil Najdi

Health Professions Education

Objective: This study aims to identify and delineate the essential components to be included in the public health internship logbook for medical students during their internships at health center facilities. Key elements to be defined include educational objectives, as well as specific skills and tasks that students are expected to acquire throughout their internship experience.

Materials and methods: A comprehensive methodology was developed, structured into three distinct phases. The first phase utilized the Delphi technique to establish pedagogical objectives for public health internships. The second phase involved analyzing feedback from public health professionals who supervise students at health centers. The …

El Maíz Del Abuelo: Fidel Márquez Sanchez’S Legacy And Mexico’S Historical Maize Agriculture, Lucia Marquez-Uppman

Scripps Senior Theses

The Green Revolution was an era of scientific development in productive agricultural methods and technologies in the mid-twentieth century. High-yielding seed varieties, artificial fertilizers, irrigation infrastructure, pesticides, and herbicides all developed from this period. Texcoco, Mexico was the center of much of the Green Revolution's education and research from the 1940s onward at the Autonomous University of Chapingo, a prestigious agricultural school, with funding from the US-based philanthropic Rockefeller Foundation. Powerful consequences in the globe's agriculture emerged from the Green Revolution, including the production of maize, a staple crop in Mexico, especially for Indigenous and campesino populations. My abuelo, Fidel …

Association Of Prenatal Exposure To Phthalates And Phenols With Adverse Pregnancy Outcomes, Misa Hayasaka, Diana Aboukhater, George Saade, Tetsuya Kawakita

Department of Obstetrics & Gynecology Faculty Publications

OBJECTIVE:

To evaluate the association between prenatal exposures to phthalates and phenols and adverse pregnancy outcomes, including preterm birth (PTB), small-for-gestational-age (SGA) birth weight, and gestational diabetes mellitus (GDM).

METHODS:

This study analyzed data from the Environmental Influences on Child Health Outcomes consortium, which harmonized longitudinal data on more than 30,000 pregnancies and 57,000 children from 69 cohorts across the United States and Puerto Rico. Pregnancy outcomes included PTB, SGA, and GDM, identified from medical records or self-reports. Generalized estimating equations models with Poisson distribution and robust variance were used to estimate relative risks (RRs) and 95% CIs per interquartile …

Association Between The Social Vulnerability Index And Adverse Pregnancy Outcomes, Tetsuya Kawakita, Misa Hayasaka, Lindsay Robbins, Juliana Martins, George Saade

Department of Obstetrics & Gynecology Faculty Publications

Objective: To assess the association between the Social Vulnerability Index (SVI) and racial disparities in pregnancy outcomes across U.S. counties and to quantify these racial disparities.

Methods: This was a cross-sectional study using restricted Centers for Disease Control and Prevention data sets, including natality data sets, fetal death data sets, and all-cause mortality data sets from 2016 to 2021. We limited analyses to Black or White individuals aged 15-44 years from 3,114 U.S. counties. Participants were categorized into quartiles based on county-level SVI. The primary outcome was maternal mortality rate while pregnant or within 42 days of the end of …

Models Of Machine Learning To Diagnose Chronic Kidney Disease Using A  Weka-Based Classifier, Shaymaa Adnan Abdulrahman, Sameerah Faris Khlebis

Mesopotamian Journal of Artificial Intelligence in Healthcare

In the present day, humans are confronted with a variety of diseases as a result of their lifestyle and the current environmental conditions. Therefore, it is crucial to identify and predict these diseases in their early phases in order to prevent their severe manifestations. Manually identifying maladies is a challenging task for physicians on a regular basis. Predicting chronic illnesses is the aim of this article. This goal is applicable through a state-of-the-art approach to classification correctly identifies people with chronic illnesses. Predicting maladies is also a difficult endeavor. Therefore, disease prediction is significantly influenced by data mining. To get …

Data Mining Driven Segmentation Of Health Insurance Policyholders Using K-Means Clustering, Farah Ali Khairi, Laith Farhan, Oluwaseun A. Adelaja

Mesopotamian Journal of Artificial Intelligence in Healthcare

This study illustrates a data‐driven approach to the segmentation of health insurance policyholders based on K-Means clustering of an open insurance dataset. Key demographic and financial features like age, body mass index (BMI), dependents, annual medical spending, and premium payment were normalized first to ensure comparability. The optimal number of clusters (k = 3) was determined using silhouette analysis, and three clusters were formed: (1) young, low‐cost individuals, (2) middle‐aged medium‐cost individuals, and (3) old, high‐cost individuals. Cluster centroids provide actionable profiles that can be utilized by insurers for target marketing, risk profiling, and development of customized plans. A set …

Dictyostelids: The Second Major Group Of Slime Molds, P. Liu, Z.J. Zhang, J.H. Ge, Y. Zou, Z. Li, S. Li, Y. Li, S.L. Stephenson

Biological Sciences Faculty Publications and Presentations

The dictyostelids (also called cellular slime molds or social amoebae) are among the more abundant and widespread groups of microorganisms in terrestrial ecosystems. Despite this fact, they are totally unknown to most people, who sometimes confuse the dictyostelids with myxomycetes (or plasmodial slime molds). The first dictyostelid (Dictyostelium mucoroides) was described by the German Oskar Brefeld in 1869. More than 180 species are now known, and these organisms have been recorded from the high arctic to the subantarctic. The primary microhabitat for dictyostelids is the soil/humus layer on a forest floor, but they also occur in a number of other …

S-Methyl Cysteine Sulfoxide And Its Potential Role In Human Health: A Scoping Review, Caroline R. Hill, Alex Haoci Liu, Lyn Mccahon, Liezhou Zhong, Armaghan Shafaei, Lois Balmer, Joshua R. Lewis, Jonathan M. Hodgson, Lauren C. Blekkenhorst

Research outputs 2022 to 2026

Higher intakes of cruciferous and allium vegetables are associated with a lower risk of cardiometabolic-related outcomes in observational studies. Whilst acknowledging the many healthy compounds within these vegetables, animal studies indicate that some of these beneficial effects may be partially mediated by S-methyl cysteine sulfoxide (SMCSO), a sulfur-rich, non-protein, amino acid found almost exclusively within cruciferous and alliums. This scoping review explores evidence for SMCSO, its potential roles in human health and possible mechanistic action. After systematically searching several databases (EMBASE, MEDLINE, SCOPUS, CINAHL Plus Full Text, Agricultural Science), we identified 21 original research articles meeting our inclusion criteria. These …

The Anatomy Of Body Shaming In Sports Coaching, Valeria Varea, Robert S. Primus, Natalie Barker-Ruchti, Mikael Quennerstedt

Research outputs 2022 to 2026

Stories of body shaming in sports coaching are becoming widespread, and can intentionally, unintentionally, or inadvertently be used in different sports coaching practices. These practices do not necessarily intend to harm athletes. The aim of this paper is to explore body critical and body sensitive sport coaching practices that have the potential to be shaming, or as we call it in the title, the ‘anatomy’ of body shaming. The study used photo elicitation interviews including vignettes for data generation with 12 coaches from nine different sports. The results demonstrate that body criticality and body sensitivity function in different subtle ways …

People With Hip Osteoarthritis Have Reduced Quadriceps Voluntary Activation And Altered Motor Cortex Function, Myles C. Murphy, Molly Coventry, Janet L. Taylor, Ebonie K. Rio, Andrea B. Mosler, Jackie L. Whittaker, Christopher Latella

Research outputs 2022 to 2026

Aims: Compare quadriceps voluntary activation, corticospinal and intracortical excitability between people with and without hip osteoarthritis (OA). Exploratory objectives include quantifying the association of corticospinal/intracortical excitability with voluntary activation, corticospinal/intracortical excitability with hip related pain, and motor threshold with motor cortex inhibition and facilitation. Methods: Case-control study including participants with clinically and radiologically confirmed hip OA and non-OA controls. Quadriceps voluntary activation was assessed using twitch interpolation via femoral nerve stimulation. Single- and paired-pulse transcranial magnetic stimulation over the motor cortex assessed resting motor threshold (RMT), active motor threshold (AMT), short-interval intracortical inhibition (SICI), intracortical facilitation (ICF) and silent period. …

Dough Rheology Properties As Affected By The Inclusion Of Oat Drink Residue Flour: A Multivariate Analysis Approach, Mahmoud Said Rashed, Eimear Gallagher, Jesus M. Frias, Milica Pojić, Shivani Pathania

Articles

The global shift towards plant-based food consumption presents significant environmental benefits, yet the consequential rise in related by-products still imposes a challenge to be addressed. The present work was carried out to evaluate the rheological properties of bread dough as affected by the incorporation of dry fractionated oat drink residue flours as a functional ingredient to identify the optimum condition for incorporating fibre-rich ingredients in bakery products. Mechanically dry fractionated, dried oat drink residue flour of particle size F1: > 150, F2: 150-224, and F3: 224-300 μm was blended with strong wheat flour at 10% and 20% substitution levels of the …

Farmers' Experiences Of Transitioning Towards Agroecology: Narratives Of Change In Western Europe, Maria Markiewicz-Keszycka, Áine Macken-Walsh, Aileen Carter, Simon Mooney, Emma J. Devereux, Maeve Henchion, Paul Hynds

Conference papers

Transitioning to agroecology on dairy and beef farms is touted as a sustainable response to environmental externalities. The current study conducted narrative interviews with farmers who transitioned towards agroecological food production by implementing pro-environmental diversification measures in the Republic of Ireland, the United Kingdom and France. The study aimed to determine farmers' experiences of agroecology and used a thematic approach for the analysis. Results indicate that the motivations, values and principles of farmers transitioning to agroecology are closely aligned with the ideology of the new/peasantry. Farmers' decisions were primarily influenced by ecological principles and a sense of responsibility towards environmental …

Social Care Worker: The Shaping Of An Emerging Title., Martin Power

Irish Journal of Applied Social Studies

The inclusion of the title social care worker in the Health and Social Care Professionals Act (2005) was a crucial development in the journey toward the professionalisation of social care work. With the two year grand-parenting window for entry to the register closed at the end of November 2025, the regulation of social care work has now begun. While this will mean that a definitive number rather than estimates of the number of social care workers in Ireland will be available, ambiguities remain. For example, in spite of the passing of two decades since the inclusion of social care worker …

Il-1 Signal Inhibition In Alcohol-Related Hepatitis: A Randomized, Double-Blind, Placebo-Controlled Trial Of Canakinumab, Nikhil Vergis, Vishal Patel, Karolina Bogdanowicz, Justyna Czyzewska-Khan, Rosemary Keshinro, Francesca Fiorentino, Emily Day, Paul Middleton, Stephen Atkinson, Thomas Tranah, Mary Cross, Daphne Babalis, Neil Foster, Emma Lord, Alberto Quaglia, Josephine Lloyd, Robert Goldin, William Rosenberg, Richard Parker, Paul Richardson, Steven Masson, Gavin Whitehouse, Cyril Sieberhagan, David Patch, Nikolai Naoumov, Ashwin Dhanda, Ewan Forrest, Mark Thursz

Peninsula Medical School

Background and Aims: Short-term mortality in alcohol-related hepatitis (AH) is high, and no current therapy results in durable benefit. A role for interleukin (IL)-1β has been demonstrated in the pathogenesis of alcohol-induced steatohepatitis. This study explored the safety and efficacy of canakinumab (CAN), a monoclonal antibody targeting IL-1β, in the treatment of patients with AH. Methods: Participants with biopsy-confirmed AH and discriminant function ≥32 but Model for End-Stage Liver Disease ≤27 were randomly allocated 1:1 to receive either CAN 3 mg/kg or placebo (PBO). Liver biopsies were taken before and 28 days after treatment. The primary endpoint was the overall …

Artificial Intelligence Powered System For Epilepsy Detection Using Eeg Biomarkers, Ali H. Al-Nuaimi, Shaymaa Al-Juboori

School of Engineering, Computing and Mathematics

One of the most prevalent neurological disorders is epilepsy. Epileptic seizures can occurrepeatedly in people with the condition for no recognisable reason. The diagnostic methodsdependent on EEG are promising. EEG has uncovered the dynamic functioning of all brain areasthroughout time. Its low cost, non-invasiveness, and simply make it crucial for clinicalevaluations of brain function. Integrating multiple EEG biomarkers as a compound biomarkercould provide a high performance that may accelerate the diagnosis speeds. Artificial intelligencetechniques such as machine learning and deep learning provide a significant result in healthcareapplications. Logistic Regression (LR), Naive Bayes (NB), and Neural Network (NN) wereevaluated using a …

Educator Professional Subjectivities In Gamification: Knowing, Being And Doing, Natalie-Jane Howard, Elizabeth J. Cook

Research outputs 2022 to 2026

Gamification has emerged as a prominent innovation in contemporary education, yet its influence on the enactment of educators’ professional subjectivities remains underexplored. As such, little is known about how online gamification applications like Kahoot shape the dynamic ways educators perceive, understand and enact their professional selves within higher education contexts. Adopting a tripartite framework of knowing (epistemological), being (ontological) and doing (praxiological), this qualitative study employed visual-elicitation interviews and remote observations with ten lecturers at a Middle Eastern college. The analysis revealed three key themes shaping educator subjectivities: creating and sharing quiz content; conforming with institutional culture; and infantilizing students …

How Young Migrants Perceive School Health Education In Sweden, D. Barker, A. Caldeborg, M. Quennerstedt, Valeria Varea

Research outputs 2022 to 2026

The aim of this paper is to provide insights into how young people who have been forced to migrate perceive school health education. Eighteen individuals aged 15–19 years (10 females, 8 males, average age 16.9 years) took part in either focus group interviews (n = 7) or individual interviews (n = 1). Participants were first presented with short scenarios concerning health education and were invited to use these scenarios as starting points to discuss their own experiences of health education. Participants were then presented with a collection of photographs that portrayed people displaying broad dimensions of health. Participants were asked …

Prognostic Value Of Neutrophil-To-Lymphocyte Ratio, Platelet-To-Lymphocyte Ratio, And Lactate Dehydrogenase Level In Melanoma Patients Treated With Immune Checkpoint Inhibitors, Wynne Wijaya, Muhammad Adnan Khattak, Afaf Abed, Tarek Meniawy, Michael Millward, Elin Gray, Oliver Oey

Research outputs 2022 to 2026

Introduction: Metastatic melanoma carries a poor prognosis. Immune checkpoint inhibitors (ICIs) have improved outcomes, but responses remain variable, highlighting the need for simple prognostic biomarkers. Inflammatory markers such as neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), and lactate dehydrogenase (LDH) reflect tumour burden and inflammation, though their clinical utility is unstandardised. Methods: We retrospectively analysed 103 metastatic melanoma patients treated with anti-PD-1 monotherapy at two centres in Western Australia (2014–2020). Baseline NLR, PLR, and LDH were assessed within 30 days pre-treatment. Outcomes included clinical benefit, progression-free survival (PFS), and overall survival (OS). Results: Poor ECOG performance status (PS ≥2) (RR 2.39, …

Infant Diet Recommendations Reduce Ige-Mediated Egg, Peanut, And Cow's Milk Allergies, Summer V.M. Walker, Nina D'Vaz, Rachelle A. Pretorius, Johnny Lo, Claus Christophersen, Susan L. Prescott, Debra J. Palmer

Research outputs 2022 to 2026

Background: Meta-analyses of randomized controlled trials have found that introducing eggs and peanuts earlier during infancy reduced egg and peanut allergy risk. Hence, infant feeding advice has dramatically changed from previous recommendations of avoidance to current recommendations of inclusion of common food allergens in infant diets. Objective: To compare the prevalence of IgE-mediated food allergies at 1 year of age between 2 cohorts, before and after infant feeding and allergy prevention guidelines changed. Methods: In cohort 1 (506 infants born 2006-2014), no infant feeding advice was provided to participants. In cohort 2 (566 infants born 2016-2022), when the infants were …

Comprehensive Assessment Instruments For Place-Based Sustainable Agriculture: A Scoping Review, Rebecca Voisin, Stephanie Godrich, David Blake, Ros Sambell, Saranne Herrington, Janine Joyce, Pierre Horwitz, Amanda Devine

Research outputs 2022 to 2026

A rapid transformation to sustainable agricultural production systems is necessary, requiring on-farm monitoring and measurements of key agricultural sustainability indicators. While many assessment methods for agricultural sustainability incorporate a three-pillar model of sustainability: environment, economic, and social, a step beyond this is required to support both human and planetary health. This review takes the position that a more nuanced, yet broader framing of agricultural sustainability is warranted, and identifies the measurement of additional pillars including health and nutrition, production, and responsible governance, plus overlooked aspects including Indigenous cultures. A peer-reviewed and grey literature search was conducted identifying articles (n = …