Digital Commons Network^™

Testosterone Modulation Of Muscle Transcriptomic Profile During Lifestyle Therapy In Older Men With Obesity And Hypogonadism, Viola Viola, Tagari Samanta, Maria Liza Duremdes Nava, Alessandra Celli, Reina Armamento-Villareal, Ngoc Ho Lam Nguyen, Georgia Colleluori, Yoann Barnouin, Nicola Napoli, Clifford Qualls, Benny Abraham Kaipparettu, Dennis T Villareal

Faculty, Staff and Students Publications

Background: Testosterone replacement therapy (TRT) added to lifestyle therapy can mitigate weight-loss-induced reduction of muscle mass and bone mineral density (BMD) in older men with obesity and hypogonadism.

Objective: To investigate the molecular mechanisms underlying the attenuation of muscle and BMD loss in response to TRT during intensive lifestyle intervention in this high-risk older population.

Methods: Among 83 older (≥ 65 years) men with obesity (BMI ≥ 30 kg/m2) and hypogonadism (early AM testosterone persistently < 300 ng/dL) associated with frailty (Modified Physical Performance Test score ≤ 31) randomized into 26-week lifestyle therapy plus testosterone (LT+TRT) or placebo (LT+Pbo) in the LITROS trial, 38 underwent serial muscle biopsies for the muscle transcriptomics substudy.

Results: Despite similar ~10% weight loss, lean body mass and thigh muscle volume decreased less in LT+TRT than LT+Pbo (-2% vs. -4%, respectively; p = …

Prediction Models Of Basal Energy Expenditure In Children And Adolescents Across The Bmi Spectrum Based On Room Calorimetry: A Cross-Sectional Cohort Study, Maurice Puyau, Roman Shypailo, Nancy F Butte, Salma Musaad, Fida Bacha

Children’s Nutrition Research Center Staff Publications

Background: Existing equations for prediction of basal energy expenditure (BEE) may not be accurate in children with overweight or obesity (OW/OB).

Objectives: We aimed to develop BEE prediction equations applicable to children and adolescents across a wide BMI spectrum using gold standard room calorimetry.

Methods: We measured weight, height, waist and hip circumferences, body composition (DXA), and BEE (whole room calorimetry) in a cross-sectional cohort of 1155 healthy children, 5-19 years of age. 67% of the males and 51% of the females were classified as OW/OB. We applied multiple linear regression analyses to develop BEE prediction models for each sex. …

Resilience And Coping: A Qualitative Analysis Of Cognitive And Behavioral Factors In Adults With Osteogenesis Imperfecta, Hannah E Cho, Whitney S Shepherd, Gianna M Colombo, Andrew D Wiese, W Conor Rork, Kristin M Kostick, Dianne Nguyen, Members Of The Bbdc, Chaya N Murali, Marie-Eve Robinson, Sophie C Schneider, Justin H Qian, Brendan Lee, V Reid Sutton, Eric A Storch

Center for Medical Ethics and Health Policy Staff Publications

Purpose: The aim of this qualitative study was to investigate resilience among adults with Osteogenesis Imperfecta (OI).

Materials and methods: Semi-structured interviews were conducted with 15 adults with OI. Transcripts were coded and subsequently abstracted, yielding themes specific to resilience and coping. Interview guides covered broad topics including pain challenges specific to OI, mental health issues related to OI, and priorities for future interventions for individuals with OI.

Results: Participants described resilience in the context of OI as the ability to grow from adversity, adapt to challenges resulting from OI-related injuries, and find identities apart from their condition. Psychological coping …

Introducing A Point-Of-Care Tool To Teach Health Science Students About Social Determinants Of Health, Cassandra Simpkins, Alexandra Bowman, Kathleen Bors, Meghan Allwes, Lisa Calderwood

Marshall Journal of Medicine

Background

Social determinants of health (SDoH) are recognized as modifiable drivers of optimal health and an opportunity to achieve health equity, yet many clinicians still experience barriers to addressing their patients’ social needs. To help connect patients to supportive resources, the American Academy of Family Physicians developed the Neighborhood Navigator (NN) tool. This study examined the impact of incorporating the NN tool into SDoH education for medical and pharmacy students and examined their perceptions of the tool.

Methods

This prospective study of third- and fourth-year medical and PharmD students included assessments before and after an SDoH learning activity. The survey …

Pass It Along: Learning About Health Inequities Through Project-Based Learning And A Student-Developed Workshop, Marcy S. Ekanayake-Weber, Deanna Cunha, Kristi L. Fung, Sydney Macgregor, Nicole Ribeiro, Nicholas Smith

International Journal of Transformative Teaching and Learning in Higher Education

People in marginalized communities experience reduced quality of healthcare due to complex interactions between implicit bias, stereotypes, and structural inequities, but future healthcare providers remain unprepared to confront these problems. To address the issue of health inequities in health sciences education, a project-based learning seminar for undergraduates called “Biology of Inequity” was developed and offered by the Department of Anthropology at [redacted] University in Spring semester 2022. Following the project-based learning (PBL) framework, the course was extremely interactive, culminating in a project where students were asked to “materially improve health inequalities out in the real world.” The students responded by …

Advances In Research And Development With Sylosanthes And Other Tropical Pasture Legumes, D F. Cameron, C P. Miller, L A. Edye, J W. Miles

IGC Proceedings (1977-2023)

The last 20 years have seen major advances in research and development wilh tropical legumes. Research advances have been closely associated with substantial increases in the number and diversity of genetic resource collections, Release of a wide range of new cultivars has been based on selection for plant adaptation, persistence and productivity, screening for resistance to pest's and diseases, and the development of efficient seed production. Determination of fertiliser requirements and grazing management practices has resulted in sustainable animal production from legume-based pasture systems. Extensive pasture development has now occurred in both high and low input systems. Options vary from …

Growth And Mineral Nutrition In Dichanthium Aristatum Sward Shaded By Tress, P Cruz, N M. Munier-Jolain, R Tournebize, H Sinoquet

IGC Proceedings (1977-2023)

Gliricidia sepium is an important legume tree used in the silvopastoral systems of the Caribbean area and tropical America. In this work we analysed the effect of its alley cropping on the growth and mineral nutrition of a Dichanthium aristatum sward, Results show that nitrogen uptake and conversion efficiency of solar radiation were twice as high in the shaded grass. Phosphorus and potassium uptake of dichanthium were also improved by tree presence, Better mineral nutrition and growth of a shaded sward could be related to the better water status of the .. grass leaves throughout the day, This effect may …

Contribution Of Parkia Biglobosa To The Feeding Value Of Pasture Systems In West Africa, Elly N. Sabiiti, J Cobbina, J Lambourne

IGC Proceedings (1977-2023)

Parkia (Parkia biglobosa) is an important traditional economic tree legume with several uses for the rural farmers in West Africa, although it has received only limited resenrch. Parkia is dominant in natural pastures or fallow fields that are used for livestock grazing. The tree provides shade to forage grasses and livestock, protects soil from heat and torrential tropical rains, resists fire damage and coppices very well after defoliation. Farmers grow several food crops under the canopy. The fruits, leaves and young seedlings, which are highly nutritious, form an important fodder for livestock in the dry season when natural …

Eng 1002g-600 College Composition Ii Argument And Critical Inquiry, Ashley Flach

Fall 2024

No abstract provided.

The Impact Of Using A Step-Counting Wristband On Promoting Physical Activity Before And During The Blessed Month Of Ramadan, Saleh M. Hammad, Sief Addeen Saqr

An-Najah University Journal for Research - B (Humanities)

Objectives: This study aimed to investigate the impact of using a step-counting wristband on motivating physical activity before and during the holy month of Ramadan. Methods: The researchers used the experimental method in its quasi-experimental form due to its suitability for the nature and objectives of the study. The International Physical Activity Questionnaire (IPAQ) was used to collect study data, along with the health app from Apple to calculate step counts over the six months preceding the study and during the application period. Additionally, a dummy technological wristband was utilized, explained to the sample participants as functioning to count steps …

Autonomy And Relatedness: Motivating Kindergarten Teachers In An Online Professional Development, Xuanyi Eliza Wu, Alfredo Bautista, Marc Clarà

Australian Journal of Teacher Education

Drawing on the self-determination theory, this paper focuses on two factors that are essential for individuals to be motivated, namely the psychological needs of autonomy and relatedness. We implemented three different iterations of an online PD course, entitled Chat with Children. While content was identical, the designs of autonomy and relatedness varied. Participants of this exploratory study were 417 in-service Hong Kong kindergarten teachers. We analyzed teachers’ enrollment, participation, and completion in the three iterations, and also interviewed teachers to explore their experiences of different autonomy and relatedness designs. We found that participation and completion were significantly higher in the …

Pilot Study: Initial Investigation Suggests Differences In Emt-Associated Gene Expression In Breast Tumor Regions, Kylie L. King, Hamed Abdollahi, Zoe Dinkel, Alannah Akins, Homayoun Valafar, Heather Dunn

Faculty Publications

Triple negative breast cancer (TNBC) is the most aggressive subtype and disproportionately affects African American women. The development of breast cancer is highly associated with interactions between tumor cells and the extracellular matrix (ECM), and recent research suggests that cellular components of the ECM vary between racial groups. This pilot study aimed to evaluate gene expression in TNBC samples from patients who identified as African American and Caucasian using traditional statistical methods and emerging Machine Learning (ML) approaches. ML enables the analysis of complex datasets and the extraction of useful information from small datasets. We selected four regions of interest …

Losing Battle, Pyrrhic Victory: Federal Barriers To Improving Livestock Welfare, Colleen J. Mcaulay

NULR Online

No abstract provided.

Exploring The Potential Benefits Of Tamanu For The Green Waqf Project: Economic, Social, And Environmental Perspectives, Rahmawati Apriliani

International Journal of Islamic Economics and Business Sustainability

Purpose - This study aims to explore the potential benefits of Tamanu or Nyamplung (Calophyllum Inophyllum) plant from economic, social, and environmental perspectives, particularly within the framework of Islamic economics. By examining its potential applications in halal industries, Green Waqf, and sustainable economic development, this research highlights how Tamanu cultivation aligns with Shariah principles, promotes ethical business practices, and supports social welfare through equitable resource distribution.

Design/methodology/approach - This study conducted a systematic literature review of peer-reviewed articles in the past decade (2013-2023). From several screening criteria, 48 articles indexed in Scopus were included for analysis.

Findings - Tamanu plant …

Evaluating The Performance Of Broccoli (Brassica Oleracea Var. Italica) In The Sandponics System Using Brackish Water With Biochar And Compost, Gabriel Oyebode

Theses and Dissertations

Some of the most pronounced effects of climate change on agricultural output include the depletion of freshwater resources and heightened salinization of arable land, especially in arid and semi-arid regions, adversely affecting crop yields. Many economic vegetable crops including members of the brassica family are sensitive to salt-stress. The use of organic soil amendments such as biochar and compost as complimentary nutrient sources in the sandponics system can improve the performance of crops. The study aimed to evaluate the effect of organic amendment on the growth performance and yield of broccoli and Nile tilapia (Oreochromis niloticus) under brackish …

Evaluating The World Health Organization's Hearts Model For Hypertension And Diabetes Management: A Pilot Implementation Study In Guatemala, Irmgardt Alicia Wellmann, Luis Fernando Ayala, Taryn M Valley, Vilma Irazola, Mark D Huffman, Michele Heisler, Peter Rohloff, Rocío Donis, Eduardo Palacios, Manuel Ramírez-Zea, David Flood

2020-Current year OA Pubs

BACKGROUND: The World Health Organization HEARTS Technical Package is a widely implemented global initiative to improve the primary care management of cardiovascular disease risk factors. The study's objective is to report outcomes from a pilot implementation trial of integrated hypertension and diabetes management based on the HEARTS model in Guatemala.

METHODS: We conducted a single-arm pilot implementation trial over six months from October 2023 to May 2024 in 11 Guatemalan Ministry of Health primary care facilities in two districts. The pilot evaluated a package of five HEARTS-aligned implementation strategies to improve the pharmacological treatment of hypertension and diabetes. The primary …

The Relationship Between Self-Efficacy And Self-Management Behavior In Gestational Diabetes Mellitus Control, Fatimah Dwi Cahyani, Shrimarti Rukmini Devy

Journal of Indonesian Health Policy and Administration

Diabetes mellitus gestasional (DGM) merupakan kondisi kesehatan yang meningkat dalam kehamilan dan dapat menyebabkan komplikasi serius bagi ibu dan janin. Self-management yang mencakup pemahaman, penerapan, dan pemeliharaan perilaku kesehatan memiliki peran kunci dalam mengelola DGM. Health Belief Model (HBM) digunakan sebagai kerangka kerja teoretis yang membentuk dasar intervensi untuk meningkatkan self-efficacy pada ibu hamil dengan GDM. Studi ini menganalisis hubungan antara efikasi diri dan manajemen diri dalam pengendalian diabetes gestasional pada ibu hamil. Artikel ini adalah tinjauan pustaka dengan menerapkan metode pencarian literatur. Pencarian literatur dilaksanakan melalui tiga basis data yaitu PubMed, Scopus, dan Google Scholar, yang mencakup artikel-artikel yang …

Does College Guarantee Economic Mobility?: Incorporating Lost In-Kind Benefits Into The Calculation, Amy S. White

Publications and Research

Average salaries of college graduates are higher than salaries of those without degrees. However, the experience of graduating and out-earning the income requirements for in-kind or entitlement benefits like Medicaid, public assistance, Supplemental Nutritional Assistance Plan, and/or Section 8 housing vouchers are not taken into consideration in any mobility calculation nor are students prepared to lose their benefits. Teaching at an urban commuter school in a financially disadvantage borough, I have identified a gap in the research literature and supportive services for these low-income students. This opinion piece further describes the problem and highlights areas for future action and research.

Nutritional Supplements: Necessity Or Overhyped?, Harpreet Kour

Indian Journal of Health Sciences and Biomedical Research KLEU

No abstract provided.

Title-Rare Case Of Retroperitoneal Colon Perforation In Advanced Squamous Cell Carcinoma Of Kidney, Kumar Vinchurkar, Shekhargouda Deshetti, Imtiaz Ahmed

Indian Journal of Health Sciences and Biomedical Research KLEU

Squamous cell carcinoma (SCC) of the renal pelvis is an uncommon tumor typically linked to chronic renal stone disease. This tumor is inherently aggressive and generally associated with a poor prognosis. We present a case involving a patient with retroperitoneal descending colon perforation in advanced squamous cell carcinoma of kidney probably secondary to radiation. Radiation-induced gastrointestinal perforation necessitates emergency surgery, and there is a lack of high-quality evidence to support the effectiveness of any preventive measures. In this review, we provide an overview of the clinical manifestations, risk factors, mechanisms, and treatments associated with radiation-induced gastrointestinal perforation. A thorough treatment …

Socio-Demographic And Clinico-Obstetric Profile Of Human Immunodeficiency Virus And Hepatitis B Virus Positive Antenatal Clinic Attendees In A Cottage Hospital In Nigeria: A Five-Year Retrospective Study, Alphonsus Rukevwe Isara, Akinwumi Fajola, Olusola Peter Aduloju, Rebecca Ogbimi

Indian Journal of Health Sciences and Biomedical Research KLEU

BACKGROUND: Sexually transmitted infections especially HIV and HBV significantly contribute to morbidity and mortality in pregnant women and their children especially in sub-Saharan Africa.

OBJECTIVE: This study reviewed the socio-demographic, clinical and obstetric profile of HIV and HBV positive pregnant women attending ANC in Obio Cottage Hospital, Port Harcourt, Nigeria.

METHODOLOGY: A retrospective cross-sectional study which reviewed the records of HIV and HBV positive pregnant women who attended ANC clinic from January 2018 to December 2022. Data was analyzed using SPSS version 26.

RESULTS: A total of 496 pregnant women with a mean age of 31.3 ± 4.9 years …

Comparing 17Β-Estradiol And Progesterone Concentrations In Young, Physically Active Females: Insights From Plasma Versus Serum Analysis, Samantha N. Rowland, Mariasole Da Boit, Rachel Tan, Liam M. Heaney, Stephen J. Bailey

All Faculty Open Access Publications

Serum measurements of 17β-estradiol and progesterone are widely used to verify menstrual cycle status and confirm contraceptive use, often through commercially available immunoassay kits. However, no studies have investigated whether blood collection tube chemistries influence hormone concentrations in young females, despite assays permitting the use of different biofluids with similar reference ranges. In this study, venous blood was sampled from physically active females (n = 25) using Ethylenediaminetetraacetic acid (EDTA) and serum vacutainers, and 17β-estradiol and progesterone concentrations were measured using competitive immunoenzymatic assays. Median plasma concentrations of 17β-estradiol and progesterone were 44.2% (plasma 40.75 vs. serum 28.25 pg/ml) and …

Tradeoffs In The Energetic Value Of Neuromodulation In A Closed-Loop Neuromechanical System, Zhuojun Yu, Peter J. Thomas, Hillel J. Chiel

Faculty Scholarship

Rhythmic motor behaviors controlled by neuromechanical systems, consisting of central neural circuitry, biomechanics, and sensory feedback, show efficiency in energy expenditure. The biomechanical elements (e.g., muscles) are modulated by peripheral neuromodulation which may improve their strength and speed properties. However, there are relatively few studies on neuromodulatory control of muscle function and metabolic mechanical efficiency in neuromechanical systems. To investigate the role of neuromodulation on the system's mechanical efficiency, we consider a neuromuscular model of motor patterns for feeding in the marine mollusk Aplysia californica. By incorporating muscle energetics and neuromodulatory effects into the model, we demonstrate tradeoffs in the …

Examining The Effects Of A Social Cognitive Intervention Aimed At Promoting Appropriate Antibiotic Use Self-Efficacy, Erin M. Hill, Andriana Frost

Journal of Social, Behavioral, and Health Sciences

Our goal in this study was to examine the effect of a social cognitive intervention aimed at improving appropriate antibiotic use self-efficacy (AAUSE). The intervention incorporated several aspects of self-efficacy theory, including mastery, vicarious learning, and verbal persuasion. To test the effectiveness of the intervention, we used two comparison conditions—reading a pamphlet focused on antibiotic resistance (ABR) or one focused on general health (diet, physical activity, sleep). A total of 226 undergraduate students completed the study, which involved completing a series of questions/questionnaires at time 1 (preintervention), engaging in the intervention (or reading a pamphlet), and then completing the time …

Pulsating Drought And Insect Herbivory Cause Differential Effects On Soybean (Glycine Max) Genotypes That Vary In Canopy Wilting Speed, Jessica Ayala, Manish Gautam, Adrianna Peissel, George Justin, Rupesh Kariyat

Entomology and Plant Pathology Faculty Publications and Presentations

As a result of climate change, global temperatures are increasing, and water scarcity is on the rise. Soybean [Glycine max (L.) Merr] is one of the most important crops in the world due to its importance as food and feed. One of the major limiting factors for soybean production is drought, which can cause up to 80% reduction in yield. Therefore, growers and plant breeders are turning to soybean accessions that demonstrate better water use efficiency (WUE). However, in addition to drought, insect herbivory by soybean looper (Chrysodeixis includens, SBL) and fall armyworm (Spodoptera frugiperda, FAW) can also reduce soybean …

Exploring Global Research Trends On Smoking And Mental Health: A Bibliometric Analysis, Martaria Rizky Rinaldi, Jelang Hardika

Jurnal Ekonomi Kependudukan dan Keluarga

This bibliometric analysis explores global trends, author productivity, institutional and country contributions, citation patterns, and thematic relationships in the literature linking smoking and mental health. Data from the Scopus database were retrieved using specific keyword combinations related to smoking and mental health, resulting in 1,782 eligible articles after filtering for research quality. The study examines publication trends, identifies high-impact studies, and maps thematic clusters in the field. Results indicate a notable increase in publications after 2000, driven by growing recognition of smoking's impact on mental well-being and the integration of mental health considerations in tobacco control policies. Thematic mapping reveals …

Microbiome Metabolic Capacity Is Buffered Against Phylotype Losses By Functional Redundancy, Kayla Cross, Noelle Beckman, Benjamin Jahnes, Zakee L. Sabree

Biology Faculty Publications

Many animals contain a species-rich and diverse gut microbiota that likely contributes to several host-supportive services that include diet processing and nutrient provisioning. Loss of microbiome taxa and their associated metabolic functions as result of perturbations may result in loss of microbiome-level services and reduction of metabolic capacity. If metabolic functions are shared by multiple taxa (i.e., functional redundancy), including deeply divergent lineages, then the impact of taxon/function losses may be dampened. We examined to what degree alterations in phylotype diversity impact microbiome-level metabolic capacity. Feeding two nutritionally imbalanced diets to omnivorous Periplaneta americana over 8 weeks reduced the diversity …

Efektivitas Kartu Permainan Dan Kombinasi Video Animasi -Kartu Permainan Dan Terhadap Kepatuhan Minum Tablet Tambah Darah, Ardi Bastian, Agustin Widyowati, Riza Yuliawati, Kristin Ernawati, Dian Mustikawati

Perilaku dan Promosi Kesehatan: Indonesian Journal of Health Promotion and Behavior

Background: Screening results at the Baron Health Center, Nganjuk Regency showed that the prevalence of anemia in adolescent girls reached 60.89%. Although counseling and provision of iron tablets to increase hemoglobin levels have been carried out, adolescent girls' adherence to iron tablet is still low.

Objective: The study aims to see the differences in two educational methods to improve adolescent girls' compliance in consuming iron tablet

Method: A total of 201 adolescent girls were divided into 2 different groups. The first group was given education in the form of game cards, while the second group was given combination education cards …

Pengaruh Pemberian Edukasi Kepatuhan Konsumsi Tablet Tambah Darah (Ttd) Terhadap Peningkatan Pengetahuan Dan Sikap Remaja Putri Dan Orang Tua Di Kabupaten Bangkalan, Welldelin Yufuria Christiansi, Diah Indriani, Nendy Putra Salsabilla, Riska Oktaviana, Rery Afianto, Giovanny Yan Mario Paridy Man, Iitdrie Iitdrie, Aldiella Ayu Prasetya Astuti, Aziza Zahrotul Adha, Sri Hardianti, Aprillia Nurhayati, Tesalonika Arina Pambudi

Perilaku dan Promosi Kesehatan: Indonesian Journal of Health Promotion and Behavior

Background. The results of the Indonesian Health Survey (SKI) in 2023 showed that the prevalence of anaemia in adolescents was 14.6%. Knowledge about blood tablets is one of the factors that can influence someone’s blood tablets consumption behavior. Increasing knowledge and attitudes regarding blood tablets consumption can be done through education.

Aim. This study aims to analyse the effect of providing education on improving the knowledge and attitudes of parents and adolescent girls regarding anaemia prevention and consumption of blood supplement tablets in Socahah District, Bangkalan Regency.

Method. This study used a quasi-experimental design by designing one …

The Pulse, 2002, V13 N1, Winter, Advocate Health - Midwest

Historical Documents - Combined

Dreyer Medical Clinic, Aurora, IL: An issue of The Pulse, a publication for Dreyer Medical Clinic patients. This was a newsletter published for patients reporting on Dreyer news, events, classes, and staffing updates.