Digital Commons Network^™

Nutr 221n.00: Basic Human Nutrition, Laura M. Granlund

University of Montana Course Syllabi, 2021-2025

No abstract provided.

Chmy 121n.00: Introduction To General Chemistry, Eric A. John

University of Montana Course Syllabi, 2021-2025

No abstract provided.

El Leñador, February 2025, El Leñador Staff

El Leñador Newspaper

El Leñador is an English and Spanish newspaper produced by Humboldt State University students. Our staff cover and provide news to Latinx and other diverse communities on campus and in Humboldt County. We are committed to providing relevant news and expanding the representations and stories told about people of color and other marginalized groups. Our work helps create more social, political and cultural diversity in local media.

El Leñador es un periodico en español y inglés producido por estudiantes de la Universidad Estatal de Humboldt. Nuestro personal cubre y provee noticias a la comunidad Latinx y otras comunidades diversas en …

In Vitro Hydrolysis Of Areca Nut Xenobiotics In Human Liver, Vincenzo Paolillo, Mahendran Jayakumar, Colton Sheperd, Andrew Tran, Stephanie Hoang, Nhu Dao, Parag Jain, Alan L Myers

Faculty, Staff and Student Publications

Areca nut (AN) is a substance of abuse consumed by millions worldwide, in spite of established oral and systemic toxicities associated with its use. Previous research demonstrates methyl ester alkaloids in the AN, such as arecoline and guvacoline, exhibit mood-altering and toxicological effects. Nonetheless, their metabolism has not been fully elucidated in humans. In the present study, an HPLC-UV bioanalytical method was developed to evaluate the hydrolytic kinetics and clearance rates of arecoline and guvacoline in human liver microsomes (HLM) and cytosol (HLC). The bioassay was capable of quantifying arecoline and guvacoline (and carboxylate metabolites arecaidine and guvacine, respectively) with …

February 2025, Swosu Bulldog Wellness Committee

SWOSU BULLDOG WELLNESS

February is the Month that we Celebrate Love. Here are a few tips on how to Love yourself more.

Validation Of A Brief Food Parenting Measure For Fathers: A Test Of Factorial Validity, Measurement Invariance, Internal Reliability, And Concurrent Validity, Brian K. Lo, In Young Park, Melissa Mcternan, Yilin Wang, Alejandra Cantu-Aldana, Brent A. Mcbride, Katherine W. Bauer, Jess Haines, Kirsten K. Davison

School of Medicine Publications

Fathers are underrepresented in food parenting research partly due to the lack of succinct, theory-informed, and father-mother equivalent food parenting measurement tools. To address this, we 1) tested the factorial validity of a brief food parenting measure utilizing a subset of items from the Comprehensive Feeding Practices Questionnaire (CFPQ) to represent coercive control, structure, and autonomy support, 2) assessed the extent to which the brief tool works similarly in fathers and mothers (i.e., measurement invariance), and 3) evaluated its internal reliability and concurrent validity. Participants included 1071 fathers of children aged 2–6 years and 487 of their co-parents (mothers) from …

Osteoporosis In Relation To A Bone-Related Aging Biomarker Derived From The Urinary Proteomic Profile: A Population Study, Yu-Ling Yu, Dries S. Martens, De-Wei An, Babangida Chori, Agnieszka Latosinska, Justyna Siwy, Augustine N. Odili, Katarzyna Stolarz-Skrzypek, Gladys E. Maestre, Kei Asayama

School of Medicine Publications

Screening for and prevention of osteoporosis and osteoporotic fractures is imperative, given the high burden on individuals and society. This study constructed and validated an aging-related biomarker derived from the urinary proteomic profile (UPP) indicative of osteoporosis (UPPost-age). In a prospective population study done in northern Belgium (1985-2019), participants were invited for a follow-up examination in 2005-2010 and participants in the 2005-2010 examination again invited in 2009-2013. Participants in both the 2005-2010 and 2009-2013 examinations (n = 519) constituted the derivation (2005-2016 data) and time-shifted validation (2009-2013 data) datasets; 187 participants with only 2005-2010 data formed the synchronous validation dataset. …

A Child-Centred Research Checklist To Improve The Design And Reporting Of Paediatric Research Studies: A Descriptive Mixed Methods Study, Mandie Foster, Lisa Whitehead, Therese A. O'Sullivan, Julie Hill, Evalotte Mörelius

Research outputs 2022 to 2026

Background: No internationally developed child-centred research checklist is currently available to enhance the quality and transparency of the development, reporting and evaluation of research undertaken with children. Objective: To develop an internationally relevant, expert informed child-centred research checklist. Design: A descriptive mixed methods study was undertaken in five sequential phases, including a Delphi component. Setting(s): Academic/international context. Methods: This study involved five sequential stages: 1. Literature review using four databases (CINAHL, MEDLINE, Scopus, PsycINFO) and analysis to identify key themes in child-centred research (January 2020). 2. Generate a questionnaire based on the key themes for international experts in child research …

S-Methyl-L-Cysteine Sulfoxide And Glucosinolate Levels In Australian-Sourced Brassica Vegetables Before And After Domestic Cooking, Caroline R. Hill, Armaghan Shafaei, Mary C. Boyce, Liezhou Zhong, Lois Balmer, Joshua R. Lewis, Jonathan M. Hodgson, Lauren C. Blekkenhorst

Research outputs 2022 to 2026

Currently no data exists on S-methyl-L-cysteine sulfoxide (SMCSO) levels in Australian-sourced vegetables and limited data exists for glucosinolates. The effect of various cooking methods on the retention of SMCSO and glucosinolates in Australian-sourced vegetables is also limited. This study measured SMCSO and ten glucosinolates in a selection of Australian-sourced Brassica vegetables, both raw and after steaming. We additionally measured SMCSO and glucosinolate levels in broccoli after microwaving, stir-frying and boiling. SMCSO contributed greater dry weight (0.6–1.9 %) than total glucosinolates combined (0.3–1.2 %) in these raw cruciferous vegetables. SMCSO levels from highest to lowest were: Brussels sprouts > broccoli > red cabbage …

Development Of 24-Hour Rhythms In Cortisol Secretion Across Infancy: A Systematic Review And Meta-Analysis Of Individual Participant Data, Laura Kervezee, Michelle Romijn, Kirsten N.G. Van De Weijer, Britney S.J. Chen, George L. Burchell, Marieke S. Tollenaar, Marcela Tamayo-Ortiz, Lauren E. Philbrook, Carolina De Weerth, Yang Cao, Joost Rotteveel, Rina D. Eiden, Rima Azar, Nicole R. Bush, Adina Chis, Grazyna Kmita, Melissa W. Clearfield, Roseriet Beijers, Michael Gröschl, Stefan A. Wudy, Andries Kalsbeek, Evalotte Mörelius, Martijn J.J. Finken

Research outputs 2022 to 2026

Context: In adults, cortisol levels show a pronounced 24-hour rhythm with a peak in the early morning. It is unknown at what age this early-morning peak in cortisol emerges during infancy, hampering the establishment of optimal dosing regimens for hydrocortisone replacement therapy in infants with an inborn form of adrenal insufficiency. Objective: We aimed to characterize daily variation in salivary cortisol concentration across the first year of life. Methods: We conducted a systematic review followed by an individual participant data meta-analysis of studies reporting on spontaneous (ie, not stress-induced) salivary cortisol concentrations in healthy infants aged 0-1 year. A one-stage …

Association Of Serum Endocannabinoid Levels With Pancreatitis And Pancreatitis-Related Pain, Marc T Goodman, Christina Lombardi, Alexa Torrens, Catherine Bresee, Jami L Saloman, Liang Li, Yunlong Yang, William E Fisher, Evan L Fogel, Christopher E Forsmark, Darwin L Conwell, Phil A Hart, Walter G Park, Mark Topazian, Santhi S Vege, Stephen K Van Den Eeden, Melena D Bellin, Dana K Andersen, Jose Serrano, Dhiraj Yadav, Stephen J Pandol, Daniele Piomelli

Faculty, Staff and Student Publications

No abstract provided.

Coccidia Vaccine Challenge And Exogenous Enzyme Supplementation In Broiler Chicken 2—Effect On Apparent Ileal Nutrient And Energy Digestibility And Intestinal Morphology 7 And 14 Days Post-Challenge, Sunday A. Adedokun, Andrew Dunaway, Richard Adefioye

Animal and Food Sciences Faculty Publications

The efficiency with which the nutrients and energy in any diet are digested, absorbed, and utilized depends on several factors, with the health status of the bird’s gastrointestinal tract playing an important role. The protozoan parasite Eimeria has been reported to significantly reduce the performance of birds because of poor absorption of nutrients in the small intestine. In this study, the effect of Eimeria sp. challenge and exogenous enzyme supplementation on performance and nutrient digestibility in broilers fed corn-soybean meal- or wheat-corn–SBM-based diets was examined. During the first 7 days post-challenge (days 14–21), in birds fed the corn–soybean-meal-based diets, the …

Factors Influencing The Adoption Of Agroecological Vegetable Cropping Systems By Smallholder Farmers In Tanzania, Essy C. Kirui, Michael M. Kidoido, Komivi S. Akutse, Rosina Wanyama, Simon B. Boni, Thomas Dubois, Fekadu F. Dinssa, Daniel M. Mutyambai

All Peer-Reviewed Publications

Vegetable production is vital to smallholder farmers, who often struggle to overcome pests, diseases, and extreme weather. Agroecological cropping systems offer sustainable solutions to these issues but their adoption rates in Tanzania remain low. This study examines the factors influencing smallholder farmers’ adoption of selected agroecological cropping systems for vegetable production in Tanzania, which remains underexplored. Using a multistage sampling technique, cross-sectional data were gathered from 525 crucifer and traditional African vegetable farming households within the Arusha and Kilimanjaro regions. Multivariate probit regression analysis, which accounts for the simultaneous adoption of multiple systems, revealed several significant variables influencing adoption. The …

Survey Of Vitamin D Supplementation Practices In Extremely Preterm Infants, Mar Romero-Lopez, Mamta Naik, Lindsay F Holzapfel, Ariel A Salas, Kaashif A Ahmad, Matthew A Rysavy, Waldemar A Carlo, Yuxin Zhang, Covi Tibe, Jon E Tyson

Faculty, Staff and Student Publications

Background: Most extremely preterm (EP) infants are vitamin D deficient (serum 25-hydroxyvitamin D levels below 20 ng/mL), and optimal supplementation practices for EP infants remain unknown. Our objective is to assess current vitamin D supplementation practices in U.S. neonatal intensive care units (NICU) for EP infants to provide baseline information for the design of future clinical trials.

Methods: We conducted an online survey to study vitamin D intake and supplementation practices in U.S. NICUs caring for EP infants. Descriptive statistics compared responses by affiliation and level of care.

Results: We analyzed responses from 253 NICUs, representing the majority of academic …

Immigration Status Checks, Emergency Medicaid Utilization, And Health Care Access For Uninsured Individuals With Kidney Disease, Katherine Rizzolo, Ryan Murray, Jade Teakell, Eric Kerns, Prakrati Acharya, Priti Patel, Prachi Sharma, Lilia Cervantes

Faculty, Staff and Student Publications

No abstract provided.

Applications Of Metabolomics And Lipidomics In The Neonatal Intensive Care Unit, Jonathan D Reiss, Samson J Mataraso, Lindsay F Holzapfel, Ivana Marić, Maya M Kasowski, Camilia R Martin, Jonathan Z Long, David K Stevenson, Gary M Shaw

Faculty, Staff and Student Publications

The metabolome and lipidome comprise the thousands of molecular compounds in an organism. Molecular compounds consist of the upstream metabolic components of intracellular reactions or the byproducts of cellular pathways. Molecular and biochemical perturbations are associated with disorders in newborns and infants. The diagnosis of inborn errors of metabolism has relied on targeted metabolomics for several decades. Newer approaches offer the potential to identify novel biomarkers for common diseases of the newborn and infant. They may also elucidate novel predictive or diagnostic measures for a variety of health trajectories. Here, we review the relevance of the metabolome and lipidome for …

Catchwater Colonialism: Reshaping Hong Kong’S Hydrology, Infrastructure, Metabolism And Landscape, 1937–1968, Jack Greatrex, Florence Mok

Research Collection College of Integrative Studies

This article explores the development of hydrological infrastructure in colonial Hong Kong between the late 1930s and the late 1960s. Utilizing archival sources in Hong Kong and London, it shows how this infrastructure fundamentally reshaped Hong Kong’s geography. By way of concrete catchwaters and metal pipes, both ‘green’ and ‘urban’ Hong Kong became counter-intuitively interconnected. This interconnection created both unintended consequences and novel opportunities for colonial governance, driving forward natural conservation, state intervention into rural society and the development of new carceral institutions. Exploring these developments provides pivotal insight into the urban history of Hong Kong, with implications for global …

Integrated Agricultural Interventions And Women’S Empowerment\ A Case Study Of “She Feeds The World” – “Aysheen Bekhirha” Program In Egypt, Pakinam Shibl

Theses and Dissertations

“She Feeds the World” program is a program that empowers women in farming communities by integrating them into the agricultural value chain. With increased access to essential resources such as land, seeds, water, and technical training, women are expected to actualize their full potential and generate more income. This paper explores the intersection of societal mobilization and economic development through a case study of the “Aysheen Bekhirha” program. By drawing on primary sources, the researcher aims to provide insights into the program’s multifaceted approach and its impact on economic and social outcomes. The analysis focuses on the significance of women’s …

The Role Of Childhood Stress In Inflammatory Skin Conditions: A Neuroimmune Investigation, Marissa Ruppe, Colin Burnette, Emily Deehan, Emily Woolhiser, Haily A. Fritts, Kelly Frasier, Aspynn Owsley, Savannah K. Fakhouri, Veronica Rodriguez

Student Publications

Emerging evidence indicates that childhood stressors, such as familial conflict, bullying, academic pressure, and traumatic events, can significantly worsen inflammatory skin conditions like atopic dermatitis (AD) and psoriasis. This review explores the underlying neuroimmune pathways that link stress to skin inflammation in children, focusing on the role of the hypothalamic-pituitary-adrenal (HPA) axis and stress-induced cytokine production. Studies have shown that chronic psychological stress leads to dysregulation of the HPA axis, resulting in elevated cortisol levels, which paradoxically impair skin barrier function and upregulate pro-inflammatory cytokines such as IL-6, TNF-α, and IL-1β. Specific stressors, such as bullying, have been associated with …

Exploring Key Factors Influencing Depressive Symptoms Among Middle-Aged And Elderly Adult Population: A Machine Learning-Based Method, Ngoc Doan Thu Tran, Yi Zhen Tan, Sapphire Lin, Fang Zhao, Yee Sien Ng, Dong Ma, Jeonggil Ko, Rajesh Krishna Balan

Research Collection School Of Computing and Information Systems

Objective: This paper aims to investigate the key factors, including demographics, socioeconomics, physical wellbeing, lifestyle, daily activities and loneliness that can impact depressive symptoms in the middle-aged and elderly population using machine learning techniques. By identifying the most important predictors of depressive symptoms through the analysis, the findings can have important implications for early depression detection and intervention. Participants: For our cross-sectional study, we recruited a total of 976 volunteers, with a specific focus on individuals aged 50 and above. Each participant was requested to provide their demographic, socioeconomic information and undergo several physical health tests. Additionally, they were asked …

Determinants Of Market Participation Among Milk Producers In Kyrgyzstan, Akhmadjon Nurullaev, Eunchun Park, Bruce L. Ahrendsen, Stijn Speelman, Lawson Connor

Agricultural Economics and Agribusiness Faculty Publications and Presentations

Numerous studies have been conducted to comprehend the economic importance of market participation for producers. However, a significant gap remains, particularly in Central Asia. This study assesses market participation drivers for Kyrgyzstan's milk producers using the Life in Kyrgyzstan dataset, encompassing a comprehensive nationwide farm-level survey. Findings reveal that household assets boost market entry and sales volume, whereas distance from markets discourages participation but can increase sales for active sellers, reflecting transportation cost strategies. The insights inform policy interventions benefiting rural small-scale milk producers in Central Asian countries that share similar cultural backgrounds.

Prospective Analysis Of Liver Stiffness Measurement By Vibration Controlled Transient Elastography As A Predictor Of Outcomes In Biliary Atresia, Jean P Molleston, Nathan P Goodrich, Wen Ye, Daniel H Leung, Ronald J Sokol, Benjamin L Shneider, Children Force Outcomes Working Group

Faculty, Staff and Students Publications

No abstract provided.

Pediatric Participation In Biobanking Related To Inflammatory Bowel Diseases, Jennifer Saccente Thompson, Sahna Reddy, Alison Shaw, Antone R Opekun, Richard Kellermayer

Faculty, Staff and Students Publications

No abstract provided.

Decolonizing Psychology As A Scientific And Ethical Necessity, Heidi Keller

Online Readings in Psychology and Culture

The starting point of this paper is the colonial heritage of mainstream psychology, and particularly of developmental psychology. The dominant paradigm is still the assumption of universality of theories and findings that originate in research from and with a tiny part of the world’s population. Associated is the neglect, even ignorance, concerning existing anthropological, cultural, and psychological ethnographic research from different communities across the globe, which demonstrate that the so-called WEIRD science (Western, Educated, Industrialized, Rich, Democratic) is different in many respects from the multitude of existing cultural patterns, representing an outlier in a statistical sense. The paper presents a …

Creating Seamless Transitions To Manage Type 1 Diabetes In Emerging Adult College Students, Carol Newton Highsmith

Journal of Research Initiatives

Type 1 Diabetes (T1D) is a complex disease that can be challenging to manage in the college environment. An effective communication strategy is vital to ensure that first-year students entering college with T1D take advantage of campus resources for self-management and self-advocacy. This qualitative study examined the perceptions of academic healthcare professionals regarding the availability and gaps in services for students with T1D at higher education institutions. Using a phenomenological approach, semi-structured interview questions were posed to 17 service providers employed in health and wellness (n=9), nursing (n=4), and student support services (n=4) at 4-year universities. The findings revealed three …

Test Of Strategies For Production And Harvest Of Edible Roots From Hydroponic Plants, Mariam Yaslem Albreiki

Theses

Hydroponic plant cultivation is becoming increasingly popular in the UAE, especially for leafy greens and fruit vegetables. By the end of the growing cycle, the roots of hydroponic plants are usually treated as crop residues, even though roots of several species are potentially edible and could be processed into food or nutraceuticals. Root crops like sweet potato or carrot might even be grown in hydroponic systems for the primary purpose of producing edible fibrous or tuberous roots. However, the use of hydroponic systems for the production of root biomass is not yet common, and most farmers strive to produce plants …

A Phase Ib Trial Of Selinexor In Combination With Immune Checkpoint Blockade In Patients With Advanced Renal Cell Carcinoma, Omar Alhalabi, Mohamed A Gouda, Denái R Milton, Hassan Ahmed Momin, Bulent Yilmaz, Bettzy Stephen, Chinenye Lynette Ejezie, Justin Tyler Moyers, Serdar A Gurses, Jeffrey How, Siqing Fu, Jordi Rodon, David S Hong, Sarina A Piha-Paul, Vivek Subbiah, Ecaterina Elena Dumbrava, Daniel D Karp, Filip Janku, Funda Meric-Bernstam, Nizar M Tannir, Aung Naing

Faculty, Staff and Student Publications

Background: Selinexor (SEL) is a nuclear exportin 1 inhibitor that blocks the transport of nuclear proteins, including tumor suppressors, to the cytoplasm. Preclinical data suggest that the combination of SEL with checkpoint blockade may result in improved response to immunotherapy.

Methods: NCT02419495 was a multiarm phase IB study of SEL in combination with other standard regimens in patients with advanced malignancies. Arm M utilized twice weekly oral SEL and intravenous nivolumab (NIVO). Arm N utilized weekly oral SEL with NIVO plus ipilimumab (IPI). The primary objective of this study was to evaluate the safety of SEL + NIVO and SEL …

Optimizing Care And Maintenance Of Enteric Tubes: Insights Into Percutaneous Radiologically Placed Gastrointestinal Luminal Tubes, Mohammad Mahdi Khavandi, Nariman Nezami, Steven Y Huang, Alda L Tam, Bruno C Odisio, Armeen Mahvash, Mohamed E Abdelsalam, Joshua D Kuban, Rahul A Sheth, Peiman Habibollahi

Faculty, Staff and Student Publications

Percutaneous enteric tubes, including gastrostomy, gastrojejunostomy, and percutaneous transesophageal gastrostomy, are essential for patients who cannot maintain adequate oral nutrition or require gastric decompression due to conditions like malignant bowel obstruction. Proper care and maintenance are crucial to prevent complications and maintain function. Enteric tubes are inserted using various techniques at different locations based on patient needs and anatomical considerations. Enteric tubes play a vital role in patient care, and continued research and innovation are necessary to improve outcomes and reduce complications. Routine care involves regular flushing and site maintenance to prevent occlusion and infection. While complications are common, they …

A Phase 2 Basket Study Of Talabostat, A Small-Molecule Inhibitor Of Dipeptidyl Peptidases, Administered In Combination With Pembrolizumab In Patients With Advanced Solid Cancers, Jibran Ahmed, Filip Janku, Daniel D Karp, Sarina A Piha-Paul, Apostolia M Tsimberidou, Timothy Anthony Yap, Bettzy Stephen, Yali Yang, Serdar Gurses, Qian Liu, Juhee Song, Funda Meric-Bernstam, Aung Naing

Faculty, Staff and Student Publications

Background: Talabostat, an oral small molecule inhibitor of dipeptidyl peptidases (DPP4 and DPP8/9), has shown synergistic activity with immune checkpoint inhibitors in preclinical studies. This open label, phase 2 basket trial assessed the antitumor activity of combining talabostat and pembrolizumab (anti-programmed death-1 antibody) in advanced solid tumor patients.

Methods: The primary objective was assessment of dose-limiting toxicity (DLT) rates in the first six patients (lead-in stage) and response rate (efficacy stage; included cohort A [checkpoint inhibitor (ICI) naive] and cohort B [ICI pretreated]) for the study treatment using the Response Evaluation Criteria in Solid Tumors (RECIST) v1.1 and immune RECIST …

Best Practices For Delivering Neoadjuvant Therapy In Pancreatic Ductal Adenocarcinoma, Jordan M Cloyd, Angela Sarna, Matthew J Arango, Susan E Bates, Manoop S Bhutani, Mark Bloomston, Vincent Chung, Efrat Dotan, Cristina R Ferrone, Patricia F Gambino, Ajit H Goenka, Karyn A Goodman, William A Hall, Jin He, Melissa E Hogg, Shiva Jayaraman, Avinash Kambadakone, Matthew H G Katz, Alok A Khorana, Andrew H Ko, Eugene J Koay, David A Kooby, Somashekar G Krishna, Liliana K Larsson, Richard T Lee, Anirban Maitra, Nader N Massarweh, Sameh Mikhail, Mahvish Muzaffar, Eileen M O'Reilly, Manisha Palta, Maria Q B Petzel, Philip A Philip, Marsha Reyngold, Daniel Santa Mina, Davendra P S Sohal, Tilak K Sundaresan, Susan Tsai, Kea L Turner, Timothy J Vreeland, Steve Walston, M Kay Washington, Terence M Williams, Jennifer Y Wo, Rebecca A Snyder

Faculty, Staff and Student Publications

Importance: Neoadjuvant therapy (NT) is an increasingly used treatment strategy for patients with localized pancreatic ductal adenocarcinoma (PDAC). Little research has been conducted on cancer care delivery during NT, and the standards for optimal delivery of NT have not been defined.

Objective: To develop consensus best practices for delivering NT to patients with localized PDAC.

Design, setting, and participants: This study used a modified Delphi approach consisting of 2 rounds of voting, and a series of virtual conferences (from October to December 2023) to reach expert consensus on candidate best practice statements generated from a systematic review of the literature …