Digital Commons Network^™

Clinical Research Center (Crc), Dennis Savaiano, Purdue University Office Of Research

University Research Core Facility Boilerplate Descriptions

No abstract provided.

The Role Of Mthfr Gene Mutation In Neurodevelopmental Disorders: Exploring Potential Correlations With Attention Deficit Hyperactivity Disorder And Anxiety, Heba Mehmood

All NMU Master's Theses

One of the most common neurodevelopmental disorders is Attention Deficit Hyperactivity Disorder (ADHD), which is often co-occurring with symptoms of depression and anxiety. The misdiagnosis and overdiagnosis of ADHD is agreed to be a prevalent problem. The methylenetetrahydrofolate reductase (MTHFR) gene has been identified as a possible contributor to ADHD. The goal of this research is to decrease the frequency at which ADHD is misdiagnosed by investigating the correlation between the MTHFR gene at the single nucleotide polymorphism (SNP) C677T to ADHD and anxiety. A group of 80 participants’ DNA samples were collected through cheek swabs following IRB approval. Participants …

Crafting History: Scrapbooks Of Hope College And The Student Experience; Collections Highlight: Women Medical Missionaries, Erika Hubbard, Charlotte Ulloa

Archives and Special Collections Quarterly

Crafting History: Scrapbooks of Hope College and the Student Experience

Column: From the Director of Archives and Special Collections

Collections Highlight: Women Medical Missionaries

Sparks And Developmental Outcomes In Out-Of-School Time Programs: Emipirical Evidence And Theory Development, Alexandra Skrocki, Gary D. Ellis, Andrea Ettekal, Darlene Locke

Journal of Youth Development

We examined relations among select components of the 4-H Thriving Model, focusing on youth sparks and four presumed determinants: program quality, developmental relationships, situational engagement, and dosage. Based on our results and results of previous studies, we propose a formal theory of youth program sparks. Three hundred fifty-six Texas 4-H youth from a variety of 4-H programs state-wide completed a questionnaire measuring sparks, program quality, developmental relationships, situational engagement, and 4-H program dosage. We measured two indicators of thriving: growth mindset and hopeful purpose. Sixty-eight percent of study participants reported being female, 28% reported being male, 1% reported being nonbinary/third …

Spotting And Responding To Health Misinformation And Disinformation, Michael J. Mcgee, Jean-Philippe Berteau

Open Educational Resources

Three one-hour lessons. In these lessons students will learn to identify health misinformation which spreads rapidly through social media, search engines, and online platforms. By generating false health news stories with AI and critically analyzing them, students will develop essential skills for public health literacy and ethical responsibility. These activities equip future health professionals with the tools to discern evidence-based information from deceptive content and provide guidance to ensure accurate and authentic communication in the field.

Non-Destructive Detection Of Fillet Fish Quality Using Mq135 Gas Sensor And Neutrosophic Logic-Enhanced System, M. Y. Shams, M. R. Darwesh, Roheet Bhatnagar, N. S. A. Al-Sattary, A. A. Salama, M. S. Ghoname

Neutrosophic Sets and Systems

This paper demonstrates the feasibility of using an electronic nose to assess fish quality by analyzing air quality and examining volatile organic compounds (VOCs) alongside physical variables, with pH, protein content, and VOCs serving as chemical reference points. Artificial intelligence algorithms were employed to predict quality and calculate regression coefficients. Using the reference neural network algorithm based on chemical and physical compounds, regression coefficients (R values) achieved were 0.99, 0.98, and 0.97, respectively. Additionally, ANFIS (Adaptive Neuro-Fuzzy Inference System) produced R values of 0.99, 0.85, and 0.98. Both fuzzy logic and ANFIS proved effective for predicting fish quality. Image processing …

Picking Through The Remnants Of Brown V. Board To Realize The Ideal Of Quality Public Education For All Children In The Post Covid-19 Era, Tiffani Darden

William & Mary Law Review

Brown, above and beyond eliminating the “separate but equal” doctrine, presented many socio-legal principles that were abdicated or diluted during the government’s COVID-19 response. This Article will address several strands recognized throughout the opinion’s seventy-year history by the courts and legal commentators that were illuminated during this period. First, the pursuit of quality education remains elusive for people of color and students from lower socioeconomic backgrounds. Second, public education continues to be an aspirational pathway to upward social mobility and building a democracy composed of educated citizens. Third, the anti-subordination construction, as opposed to the anti-classification interpretation, of the …

Assessment Of Parents’ Awareness About The Care Of Their Neonates With Neural Tube Defects, Asmaa Salah Khamis, Hayam Salah Tanatwy, Safaa Salah Ismail

Nursing

Background: Neural Tube Defects are one of the most congenital anomalies of the Central Nervous System that may happen in the neonatal period. Aim of the study: this study aimed to assess parents’ awareness about the care of their neonates with neural tube defects. Research design: A descriptive study design was used. Setting: the study was conducted at the outpatient clinic for pediatric Neurology at Ain Shams Educational Hospital. Methods: A convenient sample of 40 parents accompanied by their neonates who suffered from neural tube defects. Tools: Data was collected using three tools. Tool (I) A structured questionnaire sheet composed …

March 2025, Office Of Sustainability

Office of Sustainability Newsletter

No abstract provided.

A Study Of Secondary Traumatic Stress In Health Care Professionals In Long-Term Care., Bethany Proudfoot

Doctor of Social Work Capstone Projects

Secondary traumatic stress (STS) is a significant concern for healthcare professionals in long-term care (LTC) settings. This study explores the impact of STS on clinical staff, addressing the research question: How has STS affected employees within the LTC sector, and what resources or support can be provided to mitigate its effects? The study utilized a mixed-methods approach, combining survey data from clinical staff across five LTC facilities in Ohio, incorporating the survey data measuring levels of STS and qualitative responses. Findings revealed that 64% of participants experienced high to severe levels of STS, with symptoms including anxiety, depression, sleep disturbances, …

Insulin Receptor Responsiveness Governs Tgfβ-Induced Hepatic Stellate Cell Activation: Insulin Resistance Instigates Liver Fibrosis, Wang-Hsin Lee, Evelyn A. Bates, Zachary A. Kipp, Sally Pauss, Genesee J. Martinez, Cheavar A. Blair, Terry D. Hinds Jr.

Markey Cancer Center Faculty Publications

The insulin receptor (INSR) has been shown to be hyperactive in hepatic stellate cells (HSCs) in humans and rodents with liver fibrosis. To explore HSC cellular mechanisms that INSR regulates during pro-fibrotic stimulation, we used CRISPR-Cas9 technology. We knocked out a portion of the INSR gene in human LX2 HSC cells (INSRe5- 8 KO) that regulates insulin responsiveness but not the insulin-like growth factor (IGF) or transforming growth factor-β (TGFβ) signaling. The INSRe5- 8 KO HSCs had significantly higher cell growth, BrdU incorporation, and lower TP53 expression that suppresses growth, and they also exhibited increased migration compared to the Scramble …

Exploring Oxylipins In Host–Microbe Interactions And Their Impact On Infection And Immunity, Robert J. Neff, Christopher D. Radka

Markey Cancer Center Faculty Publications

Plasma lipids are essential components of biological systems, transported through interactions with proteins to maintain cellular functions. These lipids exist in various forms, such as fatty acids, glycerolipids, glycerophospholipids, sphingolipids, sterols, and prenol lipids, derived from dietary intake, adipose tissue, and biosynthesis. While the association between certain fatty acids and cardiovascular diseases has been widely recognized, polyunsaturated fatty acids (PUFAs) exhibit cardioprotective effects, reducing risks of arrhythmias and heart-related mortality. This is due to their role in the production of eicosanoids, which modulate inflammation. Chronic inflammation, particularly in obesity, is significantly influenced by fatty acids, with saturated fatty acids promoting …

The Prevalence Of Alzheimer’S Disease Among Diabetic Patients In Saudi Arabia, Alhanouf S. Alqudah, Nahed S. Abaalkhail, Alanoud S. Alturki, Yasmen S. Naseer, Sara K. Almansour

Saudi Medical Journal

Objectives: To investigate the knowledge of Alzheimer’s disease (AD) among 228 Saudi adults with diabetes, aiming to assess cognitive awareness through a questionnaire. It explores risk factors, symptoms, prevention strategies, and attitudes towards dementia, while integrating demographic data to illuminate cognitive landscapes and correlations between diabetes and cognitive health. Methods: Trained dietitians administered questionnaires to 228 adult Saudi diabetic participants, focusing on their understanding of AD across various domains. The study employed validated tools for data collection and amalgamated responses with demographic and medical details. Results: Of the 228 participants, 56.6% were female. Findings revealed a high acknowledgment of 3 …

Hospital Readmission After An Acute Admission To Internal Medicine: Causes And Risk Factors In A Tertiary Care Center In Saudi Arabia, Mutaz H. Althobaiti, Khaled A. Alkhowaiter, Duha K. Alahmadi, Omar S. Baharoon, Al-Zahraa S. Almahlawi, Mohammed Alqahtani, Hamdan H. Al-Jahdali, Jinan Z. Shamou, Laila A. Layqah, Salim A. Baharoon

Saudi Medical Journal

Objectives: To investigate the risk factors associated with single and multiple hospital readmissions within 30 days of discharge. Methods: A retrospective study carried out during 2019 at King Abdulaziz Medical City in Riyadh, Saudi Arabia. Using simple random sampling with an estimated prevalence of readmission rates between 10-20%, the calculated sample size was 200 patients. Patients were classified into 2 categories: patients with single or multiple readmissions. For comparison of categorical variables, the Chi-square test and Fisher’s exact test were employed as relevant. Means comparisons were carried out using independent samples t-test. Multivariate logistic regression analysis was implemented to identify …

Overexpression And Biophysical And Functional Characterization Of A Recombinant Fgf21, Phuc Phan, Jason Hoang, Thallapuranam Krishnaswamy Suresh Kumar

Chemistry & Biochemistry Faculty Publications and Presentations

Fibroblast growth factor 21 (FGF21) is an endocrine FGF that plays a vital role in regulating essential metabolic pathways. FGF21 increases glucose uptake by cells, promotes fatty acid oxidation, reduces blood glucose levels, and alleviates metabolic diseases. However, detailed studies on its stability and biophysical characteristics have not been reported. Herein, we present the overexpression, biophysical characterization, and metabolic activity of a soluble recombinant FGF21 (rFGF21). The far-UV circular dichroism spectra of rFGF21 show a negative trough at 215 nm, indicating that the protein’s backbone predominantly adopts a β sheet conformation. rFGF21 shows intrinsic tyrosine fluorescence at 305 nm. Thermal …

Enhancing Competency-Based Learning With Neutrosophic Regression And The Deming Cycle, Dr Hortencio Flores Flores, Dr. Irma Reyes Blácido, Dr. Magda Patricia Ramos Cevallos, Dr. Nemesia Hidalgo Penadillo Hidalgo Penadillo, Mg. Luz Magali Villarroel Nuñez

Neutrosophic Sets and Systems

This article introduces a novel approach to enhance competency-based learning by combining the Deming Cycle with neutrosophic statistics. Competency-based education focuses on practical skills, but uncertainty in student performance and assessment can hinder its effectiveness. Neutrosophic statistics, unlike traditional methods, explicitly models indeterminacy, providing a more complete picture of uncertainty in educational data. This approach integrates neutrosophic numbers into re gression analysis to predict learning outcomes and quantify the confidence level of those predictions. These predictions, with their associated indeterminacy, then inform the Deming Cycle (Plan-Do Check-Act), enabling educators to dynamically adjust teaching strategies based on data-driven in sights. This …

Releaf By Design: Eco Conscious Cannabis Packaging, Abigail Jane Fleishman

Graphic Communication

ReLeaf is an innovative project that explores the dynamic intersection of sustainability and functionality in cannabis packaging. This project explores the urgent need for environmentally responsible solutions in an industry often reliant on single-use plastic. This project uses an innovative lens to research current eco-friendly packaging using kraft paperboard tubes, ultraviolet glass jars, and post-consumer recycled (PCR) plastics. This project aims to create a packaging solution that meets industry safety standards while appealing to eco-conscious consumers by prioritizing recyclability, biodegradability, aesthetic design, and compliance with safety regulations. The branding strategy, embodied in the name “ReLeaf,” emphasizes the therapeutic benefits of …

The Cross-Sectional Association Between Lifestyle Behaviors And Breast And Cervical Cancer Screening Among Hispanic Women Along The Texas-Mexico Border, Paul Gerardo Yeh, Audrey C Choh, Susan P Fisher-Hoch, Joseph B Mccormick, David R Lairson, Belinda M Reininger

Faculty, Staff and Student Publications

Objective: Lifestyle behaviors may influence timely cancer screening, but their relationship is unknown among Hispanic women who have low cancer screening rates.

Methods: We used Cameron County Hispanic Cohort data from 2014 to 2022 to evaluate the relationship between lifestyle and compliance with mammography and Papanicolaou (Pap) screening guidelines ("up-to-date") among Hispanic women along the Texas-Mexico border. The 2018 World Cancer Research Fund scoring system characterized cancer-preventive lifestyle adherence. Multivariable logistic regression assessed the association between lifestyle behaviors and mammography and, separately, Pap screening.

Results: Among 385 age-eligible women for mammography and 412 age-eligible women for Pap test screening, up-to-date …

Determinants Of Human Development Index (Hdi): A Regression Analysis Of Economic And Social Indicators, Kuldeep Singh, Sumanth Cheemalapati, Srikanth Reddy Ramireddy, George Kurian, Prathamesh Muzumdar, Apoorva Muley

Faculty Publications - The LeMoyne Smith School of Business

This study aims to investigate the factors influencing the Human Development Index (HDI). Five variables—GDP per capita, health expenditure, education expenditure, infant mortality rate (per 1,000 live births), and average years of schooling—were analyzed to develop a regression model assessing their impact on HDI. The results indicate that GDP per capita, infant mortality rate, and average years of schooling are significant predictors of HDI. Specifically, the study finds a positive relationship between GDP per capita and average years of schooling with HDI, while infant mortality rate is negatively associated with HDI.

Caloric Restriction And Telomere Preservation In Tert Knockout Adipocyte Progenitors Does Not Rescue Mice From Metabolic Dysfunction Due To A Tert Function In Adipocyte Mitochondria, Zhanguo Gao, Yongmei Yu, Kristin Eckel-Mahan, Mikhail G Kolonin

The Brown Foundation: Institute of Molecular Medicine

Inactivation of telomerase (TERT) in adipocyte progenitor cells (APC) expedites telomere attrition, and the onset of diabetes in mice fed high-fat diet (HFD), which promotes APC over-proliferation and replicative senescence. Here, we show that time-restricted feeding or caloric restriction in the postnatal development of mice subsequently subjected to HFD prevents telomere attrition but not glucose intolerance. This metabolic effect of dietary intervention was not observed for mice with TERT KO in endothelial or myeloid cells. To characterize the telomere-independent effects of TERT in the APC lineage, we analyzed mice with TERT knockout in mature adipocytes (AD-TERT-KO), which do not proliferate …

Sources Of Well-Being And Cardiovascular Health: A Mixed Methods Investigation From The Midus Study, Julia K. Boehm, Monica Adams, Jennifer Morozink Boylan

Psychology Faculty Articles and Research

Objective

Methods

March 2025, Swosu Bulldog Wellness Committee

SWOSU BULLDOG WELLNESS

Colorectal cancer awareness!

March is National Nutrition Month!

Spring word find activity!

Namai Zambia: Final Study Technical Report, Nachela Chelwa

Sexual and Reproductive Health, Rights, and Choices

No abstract provided.

Walking Performance Is Worse In Black Than White People With Multiple Sclerosis, Robert W. Motl, Deborah Backus, Jeffrey R. Hebert, Alexander V. Ng, Kevin K. Mccully, Whitney N. Neal, Hollie Schmidt, Robert Mcburney, Prudence Plummer, Francois Bethoux, John Lowman, Gary R. Cutter

Exercise Science Faculty Research and Publications

Background

There is emerging evidence for poor health outcomes among Black people with MS, and Black people with MS may have worse walking performance than White counterparts.

Purpose

The current study examined if Black participants with MS had slower walking speed (timed 25-foot walk, T25FW) and shorter walking distance (six-minute walk, 6MW) than White participants, and if these differences were accounted for by demographic variables, physical activity, disease/clinical characteristics, and Social Determinants of Health (SDOH).

Method

The analysis included samples of Black (N = 105) and White (N = 246) participants with MS who completed the T25FW and 6MW, underwent …

Treatment Of Osteoporosis And Osteoarthritis In The Oldest Old, Daniel Pinto

Physical Therapy Faculty Research and Publications

Osteoporosis and osteoarthritis are key diseases of musculoskeletal ageing and are increasing in prevalence and burden with the progressively ageing population worldwide. These conditions are thus particularly common in ‘the oldest old’, and there are complexities of managing them within the context of extensive multimorbidity, physical and mental disability, and polypharmacy, the rates for all of which are high in this population. In this narrative review, we explore the epidemiology of osteoporosis and osteoarthritis in the oldest old before examining trials and real-world data relating to the pharmacological treatment of these diseases in older adults, including anti-resorptives and bone-forming agents …

The Relationship Between Irritable Bowel Syndrome And Metabolic Syndrome: A Systematic Review And Meta‐Analysis Of 49,662 Individuals, Yomna E. Dean, Jose J. Loayza Pintado, Samah S. Rouzan, Lucy L. Nale, Ahmed Abbas, Abdulla Aboushaira, Farah Alkasajy, Ahmed A. Ghanem, Vinayak Mahesh Patil, Yana Gordeyeva

School of Medicine Publications

Background

Studies have shown mixed results regarding the association between irritable bowel syndrome (IBS) and metabolic syndrome (MS); This study aimed to assess the susceptibility of IBS patients to MS and its individual components.

Methods

PubMed, Scopus, Embase, and Web of Science were searched on 1/1/2023. Eligible studies were screened, and data on study characteristics, IBS diagnostic criteria, and metabolic syndrome components were extracted. Data were analysed in RevMan 5.4, with results reported as relative risk (RR) or mean difference (MD) and 95% confidence intervals. Statistical significance was set at p <  0.05.

Results

IBS was associated with an increased risk of …

The Wellness Connection March 2025, Roger Williams University School Of Law Office Of Student Life

Life of the Law School (1993- )

No abstract provided.

Behavioral Or Nutritional Drive, B. N. Gaskill, H. Davis, R. P. Gosselin, J. P. Garner, J. S. Radcliffe, L. A. Robbins, K. R. Pritchett-Corning

Animal and Food Sciences Faculty Publications

Wire mouse feeders used in laboratory mouse cages typically hold enough food to feed 5 mice for two weeks. However, some mice gnaw the food provided into powder, which they do not ingest. The ground-up food fills the cage, resulting in miscalculations of food consumption, welfare issues with blocked water valves and frequent cage handling, more frequent cage changes, and economic issues of food wastage. There is a dearth of studies attempting to understand the causes behind food grinding behavior. This study, following on from previous work, sought to determine if the motivations behind food grinding were related to a …

Dairy & Food Science News, March 2025, Department Of Dairy And Food Science

Dairy & Food Science News

Message from the Department Head
Faculty & Staff Updates
Department Faculty Earn Awards
Midwest Regional Dairy Challenge Competition hosted by SDSU
Small-Scale Dairy Processing Project
Recruitment Updates & Opportunities
Recent Activity
Alumni Mentorship Program
SDSU Food Science Research in the News
Student Updates
Events & Calendar

Wayne E. Sabbe Arkansas Soil Fertility Studies 2024, Nathan A. Slaton

Arkansas Agricultural Experiment Station Research Series

Rapid technological changes in crop management and production require that the research efforts be presented in an expeditious manner. The contributions of soil fertility and fertilizers are major production factors in all Arkansas crops. The studies described within will allow producers to compare their practices with the university’s research efforts. Additionally, soil-test data and fertilizer sales are presented to allow comparisons among years, crops, and other areas within Arkansas.