Digital Commons Network^™

Study Of The Toxicity And Cell Viability Of Zirconium Oxide Nanoparticles Prepared From An Extract Of The Vitex Agnus Castus Plant, Saba H. Mahdi, Lekaa K. Abdul Karem

Baghdad Science Journal

In the current study, ZrO₂ nanoparticles were synthesized using a plant extract derived from Vitex agnus castus, and an alkaline medium such as sodium hydroxide. A biosynthetic approach was utilized to prepare zirconium oxide nanoparticles for this research project. This method stands out from others due to its cost-effectiveness, simplicity, and lack of potential risks.The prepared samples were characterized using transmission electron microscopy TEM, scanning electron microscopy SEM, Fourier transform infrared spectroscopy FT-IR, ultraviolet-visible spectroscopy UV-VIS, X-ray diffraction, and energy-dispersive X-ray spectroscopy EDX. The size of the crystal was determined using X-ray diffraction in conjunction with the Debye-Scherer equation, …

2025 March 18 - Medical Student Education Committee Minutes, Medical Student Education Committee, East Tennessee State University

Medical Student Education Committee Minutes

No abstract provided.

Let The Sunshine In: Crafting Constitutional Transparency Regulations For Content Moderation, Caitlin Ring Carlson

Seattle University Law Review

In response to public concern about the impact of social media, legislators in some U.S. states have developed laws to regulate the process of content moderation. Many include mandatory transparency and disclosure requirements, some of which courts have already deemed an unconstitutional infringement on social media platforms’ right to free expression. This article explores the parameters for crafting constitutional social media transparency regulations using existing U.S. media policy and insights from recent legal challenges. The resulting analysis identifies content neutral transparency requirements that mandate the disclosure of purely factual, non-controversial information as those most likely to withstand judicial scrutiny. Specifically, …

Adiporon, Adiponectin Receptor Agonist, Exhibits Antiproliferative And Apoptotic Effects In Ht29 And Hct116 Colon Cancer Cells, Arwa Fairaq, Ashraf N. Abdalla, Alanood S. Algarni, Yosra Alhindi

Saudi Toxicology Journal

AdipoRon is the first synthetic analog of endogenous adiponectin, which is an adipose tissue derived hormone. As it is characterized with pharmacological properties like adiponectin through binding and activating AdipoR1 and AdipoR2 receptors this makes it a target for therapeutic treatments for a multitude of disorders. In this study AdipoRon effect on HT29 and HCT116 colon cancer cells were investigated. Cytotoxic activity of AdipoRon was observed, with a significant inhibition rate in HT29 and HCT116 cells. Moreover, there was a significant decrease in the number of HCT116 colonies by clonogenicity test. In addition, cell migration assay showed significant decrease in …

Gender Differences In Weight Perceptions And Intentions Among Hispanic Youth In The United States, Kristy Gregurek

Walden Dissertations and Doctoral Studies

Childhood obesity is a global epidemic and a serious issue for children and adolescents in the United States. Despite recognition of its dangers, obesity remains a public health concern, with both genetic and environmental factors contributing to its prevalence. Of particular concern is the higher obesity rates among Hispanic children, who face disproportionately significant psychological and physical health risks. Using the theory of planned behavior, this study aimed to investigate the lack of knowledge regarding gender differences in weight perceptions and intentions, the relationship between physical activity and weight perception, and the role each may play in obesity among Hispanic …

The Importance Of Better Natural History Studies For Duchenne Muscular Dystrophy, David J. Birnkrant

Faculty Scholarship

No abstract provided.

“It Is Now In Flames, But It Will Never Burn Down”: A Conservation Of Resources Perspective On Resilience In The Yugoslav Wars, Sarah Denton

Undergraduate Honors Theses

The genocides, sieges, and brutal longevity of the Yugoslav Wars profoundly affected the lives of millions of people across the Balkans. Here, the theory of Conservation of Resources (COR) has been applied to contextualize the trauma and regrowth of survivors of these wars. COR theory suggests that people work to protect, maintain, and expand their resources, such as material assets, desirable personality traits, and religion. The threatening or actual loss of these resources induces stress. In environments that threaten or deplete many resources—such as war—other resources become essential for survival and healing. Applying this theory to the memoirs and oral …

Identifying Common Patterns In The Time Of Day Of Mindfulness Meditation Associated With Long-Term Maintenance, Ryan Fowers, Aurel Coza, Yunro Chung, Hassan Ghasemzadeh, Sara Cloonan, Jennifer Huberty, Vincent Berardi, Chad Stecher

Psychology Faculty Articles and Research

Forming a habit of practicing mindfulness meditation around the same time of day is one strategy that may support long-term maintenance and in turn improve physical and mental health. The purpose of this study was to identify common patterns in the time of day of meditation associated with long-term meditation app use to assess the importance of temporal consistency for maintaining meditation over time. App usage data were collected from a random sample of 15,000 users who had paid for an annual membership to a commercial meditation app in 2017. We constructed three measures of temporal consistency in the time …

An Exploration Of The Experiences Of Perinatal Depression And Anxiety Among Pregnant And Parenting Adolescents In The Tampa Bay Area Of Florida, Olajumoke Adetoun Ojeleye

USF Tampa Graduate Theses and Dissertations

Perinatal depression (PND) and perinatal anxiety (PNA) are increasing among pregnant and parenting adolescents (PPAs), with PNA often underrecognized. This leads to significant socioeconomic costs and adverse maternal consequences if untreated. Hence, this dissertation explores the experiences of PND and PNA among PPAs, focusing on their knowledge gaps, perception, mental health needs, care preferences, and access to PMH care. The research employs a qualitative design (free-listing and in-depth interviews) to gather participant insights. Key findings reveal that many PPAs possess limited knowledge about PNA when compared to PND. Lack of support from partners, family, and peers emerged as the topmost …

Emerging Clostridioides Difficile Ribotypes Have Divergent Metabolic Phenotypes, Firas S Midani, Heather A Danhof, Nathanael Mathew, Colleen K Ardis, Kevin W Garey, Jennifer K Spinler, Robert A Britton

Faculty, Staff and Students Publications

Clostridioides difficile is a gram-positive spore-forming pathogen that commonly causes diarrheal infections in the developed world. Although C. difficile is a genetically diverse species, certain ribotypes are overrepresented in human infections, and it is unclear if metabolic adaptations are essential for the emergence of these epidemic ribotypes. To identify ribotype-specific metabolic differences, we therefore tested carbon substrate utilization by 88 C. difficile isolates and looked for differences in growth between 22 ribotypes. As expected, C. difficile was capable of growing on a variety of carbon substrates. Further, C. difficile strains clustered by phylogenetic relationship and displayed ribotype-specific and clade-specific …

The Shorthorn: September 26, 1921

The Shorthorn Newspaper Collection: 1920s

No abstract provided.

The Utah Statesman, March 17, 2025, Utah State University

The Utah Statesman

Weekly student newspaper of Utah State University in Logan.

Week Of March 17, 2025, Student Life

College, School and Department Newsletters, Magazines, and Journals

Your weekly hub for events, resources and updates.

Aging Consumer Engagement With The Mobile Food Planner Apps In Malaysia: Investigating Gender Differences, Rajat Subhra Chatterjee, Irfan Hameed, Sheshadri Chatterjee, Ranjan Chaudhuri, Demetris Vrontis, Pantea Foroudi

Plymouth Business School

This study investigates the factors influencing older consumers’ word of mouth and intention to use meal planner applications, given that 57% of Malaysians aged 60 and above are active Internet users. The current study utilized an extended technology acceptance model and the stimulus organism response framework to examine the cognitive-affective dichotomy of usage influence. The respondents were initially selected through purposive sampling and further screened using filter questions to ensure alignment with the study objectives, resulting in data collected from 392 elderly individuals across various demographic regions of Malaysia. The analysis was conducted using the Statistical Package for Social Sciences …

Healthy Here Healthy Eating Year 1 Summary, Camille R. Velarde, Courtney A. Fitzgerald, Theresa H. Cruz

Reports & Documents

No abstract provided.

Coagulation, Fibrinolytic Parameters And Cytokines Response To Weight Reduction In Obese Saudi Women, Shehab Mahmoud Abd El-Kader, Shehab Mahmoud Abd E-Kader, Neveen Refaey, Amany Atiaa

Journal of Medical Rehabilitation Science

Background: Obesity is a relevant risk factor for major cardiovascular events due to the atherosclerotic involvement of coronary, cerebral and lower limb arterial vessels. A major role in the increased cardiovascular risk is played by platelets, which show an increased activation and a reduced sensitivity to the physiological and pharmacological anti-aggregating agents. However, no studies have been conducted to compare the effects of simple calorie restriction and those of calorie restriction combined with aerobic exercise on fibrinolytic, coagulative factors and cytokines. Objective: The aim of this study was to investigate the effect of weight reduction on the fibrinolytic, coagulative factors …

The Prevalence Of Weapon Damage: A Proportional Meta-Analysis, Sarah Lane, Erin Mccullough

School of Biological and Marine Sciences

Sexually selected weapons are tools that are used in physical fights over mating opportunities. Individuals can face dire fitness consequences if they break their weapon and can no longer fight effectively; however, the costs and consequences of weapon damage have largely been ignored. In this study, the literature was systematically searched to examine the prevalence of weapon damage, and a phylogenetically controlled proportional meta-analysis was conducted to explore factors influencing the patterns of weapon damage across the animal kingdom. A total of 36 suitable studies were identified across 74 species and 13 orders for a total of 82 effect sizes. …

Identification Of Lysosomal Lipolysis As An Essential Noncanonical Mediator Of Adipocyte Fasting And Cold-Induced Lipolysis, Yu-Sheng Yeh, Trent D. Evans, Mari Iwase, Se-Jin Jeong, Arick Park, Ali Ghasemian, Borna Dianati, Ali Javaheri, Et Al.

2020-Current year OA Pubs

Adipose tissue lipolysis is the process by which triglycerides in lipid stores are hydrolyzed into free fatty acids (FFAs), serving as fuel during fasting or cold-induced thermogenesis. Although cytosolic lipases are considered the predominant mechanism of liberating FFAs, lipolysis also occurs in lysosomes via lysosomal acid lipase (LIPA), albeit with unclear roles in lipid storage and whole-body metabolism. We found that adipocyte LIPA expression increased in adipose tissue of mice when lipolysis was stimulated during fasting, cold exposure, or β-adrenergic agonism. This was functionally important, as inhibition of LIPA genetically or pharmacologically resulted in lower plasma FFAs under lipolytic conditions. …

Exploring Profiles Of Fathers Integrating Food And Physical Activity Parenting Practices, John A Jimenez-Garcia, Louise C Mâsse, Robert L Newton, Salma M Musaad, Alicia Beltran, Teresia M O'Connor

Children’s Nutrition Research Center Staff Publications

Objective: This study aims to identify fathers' profiles integrating food parenting practices (FPP) and physical activity parenting practices (PAPP).

Design: We analysed cross-sectional data. The fathers completed the reduced FPP and PAPP item banks and socio-demographic and family dynamics (co-parenting and household responsibility) questionnaires. We identified fathers' profiles via latent profile analysis. We explored the influence of social determinants, child characteristics and family dynamics on fathers' profiles using multinomial logistic regression.

Setting: Online survey in the USA.

Participants: Fathers of 5-11-year-old children.

Results: We analysed data from 606 fathers (age = 38 ± 8·0; Hispanic = 37·5 %). Most fathers …

Genetic Associations With C-Peptide Levels Before Type 1 Diabetes Diagnosis In At-Risk Relatives, Taylor M Triolo, Hemang M Parikh, Mustafa Tosur, Lauric A Ferrat, Lu You, Peter A Gottlieb, Richard A Oram, Suna Onengut-Gumuscu, Jeffrey P Krischer, Stephen S Rich, Andrea K Steck, Maria J Redondo

Children’s Nutrition Research Center Staff Publications

Objective: We sought to determine whether the type 1 diabetes genetic risk score-2 (T1D-GRS2) and single nucleotide polymorphisms are associated with C-peptide preservation before type 1 diabetes diagnosis.

Methods: We conducted a retrospective analysis of 713 autoantibody-positive participants who developed type 1 diabetes in the TrialNet Pathway to Prevention Study who had T1DExomeChip data. We evaluated the relationships of 16 known single nucleotide polymorphisms and T1D-GRS2 with area under the curve (AUC) C-peptide levels during oral glucose tolerance tests conducted in the 9 months before diagnosis.

Results: Higher T1D-GRS2 was associated with lower C-peptide AUC in the 9 months before …

The Advanced Strategies Of Human And Donor Milk Fortification And Its Effect On Long-Term Outcome In Preterm Babies, Ashwini Lakra, Mahaveer Singh Lakra, Ishani Arora, Heena Bhandekar, Amar Taksande, Roshan Prasad, Mayur Wanjari

Chulalongkorn Medical Journal

Poor growth in intrauterine and extrauterine life and inadequate protein supplementation in babies during the first weeks of premature babies are linked to long-term growth failure and poor brain development. The calorie requirements of premature newborns cannot always be fulfilled, even with routine and traditional fortification. This is because traditional fortification procedures rely on the presumed well-known composition of human milk rather than the calculated one. The protein content of mothers' milk of preterm babies varies, decreases with breastfeeding duration, and differs with donor human milk being preserved in milk banks for a long duration. Newer fortification techniques are needed …

Mobilizing Prevention And Early Detection Of Alzheimer's Disease And Related Dementias (Adrd) In Allegheny County Through The Area Agency On Aging (Aaa), Laiba N. Mirza

Public Health Capstone Projects

1. Objectives: In collaboration with the Department of Human Services (DHS): the Area Agency on Aging (AAA) using the Healthy Brain Initiative (HBI), my capstone project will involve the development of a comprehensive literature review examining the impacts of Alzheimer’s disease and related dementias (ADRD) on patients and their caregivers. The project aims to help the AAA focus on strategies to delay the onset of ADRD in Allegheny County. It also seeks to evaluate and enhance early detection programs for ADRD established by the AAA in communities within the county. Additionally, the project will explore how public health initiatives can …

The Perceived Benefits Of And Barriers To Open-Water Swimming: A Mixed-Methods Examination, David Elliott Ph.D, Mark A. Christie Ph.D

International Journal of Aquatic Research and Education

This study set out to determine the perceived benefits of, and barriers to, open-water swimming (OWS). Adopting a mixed-methods approach, six hundred and sixty-five open-water swimmers responded to an online survey consisting of the Exercise Benefits and Barriers Scale (EBBS) and a series of open-ended questions. Data from the EBBS revealed the strongest perceived benefits to be ‘Psychological Outlook’ and ‘Life Enhancement.’ In terms of barriers, those presented in the EBBS received low ratings with only ‘Physical Exertion’ considered as being somewhat problematic. Content analysis performed on the open-ended responses showed social aspects, mental well-being, and connection to nature as …

Gw Ophthalmology On Call: 03/2025, Sana Hafiz, Julie Thomasian

GW Ophthalmology On-Call

No abstract provided.

Prison Foodways In “Orange Is The New Black”, A. E. Stearns, Morgan Wilson, Mckenzie Richard

Qualitative Criminology (QC)

"The current study adds to the literature on prison foodways and media studies by exploring the role of prison food on the show Orange is the New Black (OITNB). Specifically, this project aimed to better understand the nature of televised incarceration experiences through the way in which incarcerated characters interacted with food in the scenes. Through an analysis of 601 food-related scenes in OITNB, findings suggest: 1) food is a vehicle for additional layers of institutional control of captive bodies, 2) food plays myriad non-food roles such as medicine, a transactional medium, a vehicle for contraband, and even sexual pleasure, …

Assessing Coronavirus Disease 2019 Pandemic Impacts On The Health Of People Who Inject Drugs Using A Novel Data Sharing Model, Heather Bradley, Nicole Luisi, Anastasia Carter, Terri D. Pigott, Daniela Abramovitz, Sean T. Allen, Alice Asher, Chelsea Austin, Tyler S. Bartholomew, Marianna Baum, Amy Board, Basmattee Boodram, Annick Borquez, Kathryn A. Brookmeyer, Kate Buchacz, Janet Burnett, Hannah L.F. Cooper, Nicole Crepaz, Kora Debeck, Judith Feinberg, Chunki Fong, Edward Freeman, Nathan Woo Furukawa, Becky Genberg, Pamina Gorbach, Holly Hagan, Kanna Hayashi, Emalie Huriaux

Epidemiology and Environmental Health Faculty Publications

Objective: Using an innovative data sharing model, we assessed the impacts of the COVID-19 pandemic on the health of people who inject drugs (PWID). Design: The PWID Data Collaborative was established in 2021 to promote data sharing across PWID studies in North America. Contributing studies submitted aggregate data on 23 standardized indicators during four time periods: prepandemic (March 2019 to February 2020), early-pandemic (March 2020 to February 2021), mid-pandemic (March 2021 to February 2022), and late pandemic (March 2022 to February 2023). Methods: We present study-specific and meta-analyzed estimates for the percentage of PWID who took medications for opioid use …

Inflammation And Gut Barrier Function-Related Genes And Colorectal Cancer Risk In Western European Populations, Hannah B Mandle, Mazda Jenab, Marc J Gunter, Anne Tjønneland, Anja Olsen, Christina C Dahm, Jie Zhang, Pierre-Emmanuel Sugier, Joseph Rothwell, Gianluca Severi, Rudolf Kaaks, Verena A Katzke, Matthias B Schulze, Giovanna Masala, Sabina Sieri, Salvatore Panico, Carlotta Sacerdote, Catalina Bonet, Maria-Jose Sánchez, Pilar Amiano, José María Huerta, Marcela Guevara, Richard Palmqvist, Thyra Löwenmark, Aurora Perez-Cornago, Elisabete Weiderpass, Alicia K Heath, Amanda J Cross, Paolo Vineis, David J Hughes, Veronika Fedirko

Faculty, Staff and Student Publications

Gut barrier dysfunction and related inflammation are known to be associated with the development and progression of colorectal cancer (CRC). We investigated associations of 292 single-nucleotide polymorphisms (SNPs) from 27 genes related to endotoxins/lipopolysaccharide (LPS) sensing and tolerance, mucin synthesis, inflammation, and Crohn's disease with colon and rectal cancer risks. Incident CRC cases (N = 1374; colon = 871, rectum = 503) were matched 1:1 to controls nested within the European Prospective Investigation into Cancer and Nutrition cohort. Previously measured serum concentrations of gut barrier function and inflammation biomarkers (flagellin/LPS-specific immunoglobulins and C-reactive protein [CRP]) were available for a sub-set …

Investigation Of Dynamic Regulation Of Tfeb Nuclear Shuttling By Microfluidics And Quantitative Modelling, Iacopo Ruolo, Sara Napolitano, Lorena Postiglione, Gennaro Napolitano, Andrea Ballabio, Diego Di Bernardo

Duncan NRI Faculty and Staff Publications

Transcription Factor EB (TFEB) controls lysosomal biogenesis and autophagy in response to nutritional status and other stress factors. Although its regulation by nuclear translocation is known to involve a complex network of well-studied regulatory processes, the precise contribution of each of these mechanisms is unclear. Using microfluidics technology and real-time imaging coupled with mathematical modelling, we explored the dynamic regulation of TFEB under different conditions. We found that TFEB nuclear translocation upon nutrient deprivation happens in two phases: a fast one characterised by a transient boost in TFEB dephosphorylation dependent on transient calcium release mediated by mucolipin 1 (MCOLN1) followed …

The Spice (Sustainable, Physics-Inspired Culinary Education) Lab – A Digestible Few-Nexus Educational Platform, Carla Ramsdell

National Collaborative for Research on Food, Energy, and Water Education (NC-FEW)

The SPICE (Sustainable, Physics-Inspired Culinary Education) Lab is a unique educational platform that enables participants from a wide disciplinary background to engage and become literate in the unique connections between food, energy and water. This small but mighty space allows for outreach education in many formats, including formal college courses, university-centered hands-on activities and public outreach.

The work performed in this space fills a unique need in the FEW-Nexus education opportunities because it is adaptable to many learners and learning opportunities and its focus on kitchen science makes these concepts approachable which can later be expanded to understand other critical …

Addressing Local Food Insecurity Through A Problem-Based Learning Classroom, Kaley Mumma, Aimable Mugabo

National Collaborative for Research on Food, Energy, and Water Education (NC-FEW)

Through the frame of Problem-Based Learning (PBL), a curriculum is proposed to engage students in addressing local food insecurity. Students collaboratively define the problem, explore underlying issues, establish goals, design solutions, and implement their chosen solution to address food insecurity within their community. The importance of community engagement and utilizing local resources are highlighted in advising the implementation of this program.