Digital Commons Network^™

Establishing A Comprehensive Cancer Center: Integrating Holistic Care To Enhance The Well-Being Of Patients Undergoing Cancer Treatment, Morgan Rae Nelson

Architecture Theses

Cancer treatment is both physically and emotionally taxing, often intensified by care environments that prioritize clinical efficiency over holistic patient well-being. Thoughtful architectural design has the potential to transform these spaces into therapeutic environments that address the mental, emotional, and physical needs of patients. While holistic care models have gained traction, many facilities lack design elements that promote mental resilience, relaxation, and community connection.

Despite advancements in cancer care, a significant gap remains in how design addresses the mental and emotional well-being of patients. Many facilities continue to prioritize functionality over creating environments that foster holistic healing. This thesis investigates …

A Study Of Special Districts: Research Of Financial Indicators As Predictors Of Fiscal Distress, Scott Keith Harrison

Doctoral Dissertations and Projects

Since 1946, Special Purpose Districts (SPDs) have become the most prevalent form of government in the United States. Unfortunately, they fail more often than General Purpose (GP) governments. This study researches the predictability of the Florida State Auditor’s financial condition indicators for SPD financial health and the influence of intergovernmental transfers (IGT) on government financial health. The significance of this research lies in confirming whether a national SPD fiscal distress predictive model can be generalized to a single state. Additionally, the study researched the influence of intergovernmental transfers (IGT) on financial health. The quantitative research design used the Cox regression …

The Effect Of Cardiac Rehabilitation On Diastolic Heart Failure, Lucas Clouse

Doctoral Dissertations and Projects

The newest diagnosis approved for cardiac rehabilitation (CR) by the Centers for Medicare and Medicaid Services (CMS) was systolic heart failure with ejection fractions less than or equal to 35% in 2013. CMS did not approve diastolic heart failure as a diagnosis for CR as there has not been ample research done linking a possible benefit between the two. To date, limited research has been done regarding a CR’s resources (health education, exercise training, risk factor modification, meeting with dietitian) and its effects on diastolic heart failure. The purpose of this study is to evaluate if CR can improve quality …

Spaceflight Associated Neuro-Ocular Syndrome (Sans) And Its Countermeasures, Tuan Nguyen, Joshua Ong, Tyson Brunstetter, C Robert Gibson, Brandon R Macias, Steven Laurie, Thomas Mader, Alan Hargens, Jay C Buckey, Mimi Lan, Peter Wostyn, Cihan Kadipasaoglu, Scott M Smith, Sara R Zwart, Benjamin J Frankfort, Sarah Aman, Jessica M Scott, Ethan Waisberg, Mouayad Masalkhi, Andrew G Lee

Faculty, Staff and Students Publications

Astronauts can develop a distinct collection of neuro-ophthalmic findings during long duration spaceflight, collectively known as Spaceflight Associated Neuro-ocular Syndrome (SANS). These clinical characteristics include optic disc edema, hyperopic refractive shifts, globe flattening, and chorioretinal folds, which may pose a health risk for future space exploration. Obtaining knowledge of SANS and countermeasures for its prevention is crucial for upcoming crewed space missions and warrants a multidisciplinary approach. This review examines the potential causes and countermeasures of SANS, including space anticipation glasses, lower body negative pressure, venoconstrictive thigh cuffs, impedance threshold devices, translaminar pressure gradient modulation, centrifugation, artificial gravity, pharmaceuticals, and …

High-Throughput Phenotyping Of Early Generation Small Grains Breeding Lines To Indirectly Select For Grain Yield, Dalton Jones

All Graduate Theses and Dissertations, Fall 2023 to Present

In small grains breeding programs, breeders aim to develop better varieties by selecting for important traits like grain yield. However, it takes many years before yield can be measured because several generations of selection are required to fix lines and increase sufficient seed for yield measurements. This process can be slow and expensive

High-throughput phenotyping (HTP) is a modern approach that can increase breeding efficiency by leveraging technology to quickly measure secondary traits which can be used to indirectly select for important traits in crop plants. For example, researchers can use cameras on unmanned aerial vehicles (UAVs, i.e., drones) to …

On The Multi-Modal Psychological Experience Of Competence In Youth Sport, Liam O'Neil

All Graduate Theses and Dissertations, Fall 2023 to Present

Over the past half century, beliefs about athleticism (i.e., sport competence) have been thought of as central to motivation for youth sport. In this time, however, these competence beliefs have been narrowly studied which has limited their value in explaining youth sport participation. To expand our understanding of competence beliefs and their motivational significance in youth sport, the three studies of this dissertation tested a longstanding but understudied idea that competence beliefs encompass both judgments of, and emotions about, competence. In Study One, existing research on judgments of competence in youth sport was reviewed. This study showed that many personal …

Influence Of Physical Properties Of Fat On Product Quality, Shelf-Life And Consumer Acceptance Of Chocolate-Coated Products, Audrey Lidgard

All Graduate Theses and Dissertations, Fall 2023 to Present

In chocolate-coated products, oil migration in fats can lead to chocolate softening, filling hardening, discoloration, and lower consumer acceptance. This study examined three different fats (soy- palm-, and palm-kernel (PK) based), crystallized under different conditions (cooling rate and use of high intensity ultrasound (HIU)) to examine how the crystallization conditions impact the physical properties of confectionery products. These conditions produced fats with high and low oil binding capacities (OBCs); the ability of crystal networks to entrap liquid oil. Model systems were created to examine measurable quality degradation and consumer acceptance of chocolates placed in contact with the fats; one with …

Seeding Rate, Planting Date, And Herbicides For Dormant Seeded Safflower In Utah, Rodney Daniel Nelson

All Graduate Theses and Dissertations, Fall 2023 to Present

Dryland crop production in the Intermountain West is largely limited by the amount of precipitation received. Increasing dryland safflower (Carthamus tinctorius L.) production yields in a semi-arid climate is possible with a dormant planting but is not well understood. A two-year (2020-22) project was designed to gain an understanding of the effects of variety, seeding rate, and planting date, on dormant seeded safflower. Chemical weed control options for safflower were also evaluated. One study, conducted at three Utah State University research farms near Blue Creek, Clarkston, and Kaysville, UT, evaluated four varieties, S-208, S-333, 7325 and Hybrid-446, seeded at …

Exploring The Utilization Of Benefits And Participation Experiences Among Immigrants And Refugees In Wic Program: A Mixed-Method Study, Melissa Murillo Timoschenco

All Graduate Theses and Dissertations, Fall 2023 to Present

Food insecurity is a critical issue globally and in the United States. The USDA’s Special Supplemental Nutrition Program for Women, Infants, and Children (WIC) aims to address this by improving the nutrition of low-income pregnant women and children. However, immigrants and refugees, who are particularly vulnerable to food insecurity, often encounter barriers to accessing WIC benefits. This study aimed to: i) evaluate how immigrant and refugee families in Utah utilize WIC benefits, and ii) explore their experiences, challenges, and suggestions for improving the program. This mixed-method study combined surveys with 116 participants and in-depth interviews with 25 participants. Surveys were …

Seasonal And Temporal Influences On Successful Crossing Rates By Ungulates Of A North Utah Wildlife Overpass, Blake Ledbetter

All Graduate Theses and Dissertations, Fall 2023 to Present

Encroachment of human infrastructure fragments wild landscapes and introduces a suite of negative impacts for humans and wildlife. In Utah, roadways threaten migratory ungulates by creating a barrier to movements and preventing access to seasonal migration routes. To mitigate these conflicts, state transportation agencies often install wildlife crossing structures to allow animals to safely cross over or under roadways. Selecting the proper crossing structure requires consideration of the species of interest, landscape, location, and structural dimensions. Often there is balance between the optimal location, the dimensions of the crossing structures, and what is feasible given the landscape. In 2018, the …

Novel Horticultural Approaches For Reduced Gravity And Controlled Environment Agriculture, Sarah Elizabeth Schreck

All Graduate Theses and Dissertations, Fall 2023 to Present

On July 16, 1969, Apollo 11 achieved the first successful moon landing, marking a significant milestone in human space exploration. This historic moment effectively ended the space race between the United States and the Soviet Union, and since then, countries around the world have continued to advance their space programs. While the space race has evolved, the next major challenge lies in sending humans to Mars—a journey that could take 6 to 9 months each way, presenting numerous challenges, including the critical issue of nutritional sustainment for the crew.

This thesis addresses key aspects of a broader effort to support …

The Effect Of Dietary Protein Source On Gut Health, Spencer Lawson Schow

All Graduate Theses and Dissertations, Fall 2023 to Present

We investigated the impact of protein source in a western-style diet on colon cancer, colitis, and the gut microbiome. The Western dietary pattern is energy-dense, low in fiber, and has a sub-optimal micronutrient profile. Our group has formulated the Total Western Diet (TWD) that emulates the Western dietary pattern using survey data (NHANES), and we have demonstrated that this diet increases gut inflammation and colorectal cancer relative to a healthy control diet (AIN-93G), which is optimized for mouse health. However, the effect of protein source in the TWD and its effects on gut health have yet to be investigated.

Recent …

Uv-A Light And Heat-Activated Antimicrobial And Biodegradable Materials For Food Packaging And Preservation, Michael J. Bodily

All Graduate Theses and Dissertations, Fall 2023 to Present

Current food packaging materials are often non-biodegradable and harmful for ingestion, which poses a threat to the environment and public health. Thus far, the dangers of microbial contamination of food on human health have outweighed the risks associated with using these conventional packaging plastics. A possible solution to these issues is to use a combination of innovative materials and microbial inactivation methods that can potentially both reduce plastic waste and combat harmful microorganisms. In this study, two antimicrobial, biodegradable composites were developed and tested for their ability to inactivate two types of bacterium, Escherichia coli K12 and Listeria innocua, …

Disentangling Factors Contributing To Population Performance Of Zion Bighorn Sheep, Ian Montgomery

All Graduate Theses and Dissertations, Fall 2023 to Present

Bighorn sheep populations across the western United States face increasing challenges from habitat loss, disease, and predation. In Zion National Park and surrounding areas, survey-based estimates indicate that the desert bighorn sheep population declined from over 800 individuals in 2018 to fewer than 500 in 2021. Understanding what drives these population changes is critical for effective wildlife management and conservation. This research examined key factors influencing population growth and individual survival to inform strategies for recovery in this bighorn population.

First, we analyzed which vital rates contributed most to population trends by estimating survival and reproduction rates from ground and …

Establishing Methods For In Vitro Static Culture Of Gut Microbiomes For Nutritional Intervention Studies, Jeremy Mathew Case

Undergraduate Honors Capstone Projects

Lipid oxidation products (LOPs), which form during high-heat processing of oils common in Western diets, are known to cause inflammation and cellular damage. While LOPs have been implicated in exacerbating colitis and promoting colon tumorigenesis in mouse models, their direct impact on the gut microbiome remains poorly understood. This capstone project aimed to develop a low-cost in vitro protocol to culture the mouse gut microbiome under anaerobic conditions, enabling future investigations into the direct effects of bioactive dietary compounds such as LOPs. The study also assessed whether viable microbial communities could be recovered from fecal samples stored at -80°C. Fecal …

The Impact Of Lactoferrin And Iron-Enriched Whey On Iron Absorption, Gastrointestinal Symptoms, And Menstrual Health In Women, Mia Dustin

Undergraduate Honors Capstone Projects

Iron is an essential trace mineral involved in oxygen transport, energy metabolism, and cellular function, yet deficiency remains prevalent among women of reproductive age. In the U.S., approximately 20% of women aged 18-45 years fail to meet daily iron requirements due to lack of iron consumption in the diet, menstrual blood loss, or intense exercise, often leading to anemia, fatigue, and cognitive impairment. While ferrous sulfate is a common form of iron supplementation, it frequently causes gastrointestinal discomfort. Researchers have explored lactoferrin, a glycoprotein with immune and iron-binding properties, as an adjunct to traditional supplementation. This study examines the effects …

Survey Of Insect Pests On Cut Flowers In Utah, Elliot Roberts

Undergraduate Honors Capstone Projects

Cut flower production is a relatively new industry in the state of Utah, gaining momentum by 2020. However, little research concerning management of the crops and their pests has been conducted. One issue producers face are insects that harm the plants in ways such as feeding damage and transmission of diseases. Currently, it is unknown which insects target different species of cut flowers in Utah. Morphological identification of genera and species is often difficult or impossible because of the small size of many of the insects and minute differences between species. This project uses PCR and DNA sequencing to identify …

Navigating The Challenges Of Coccidioides Surveillance: Insights From The Environment Of El Paso County, Texas, Tanzir Hossain

Open Access Theses & Dissertations

Coccidioidomycosis, or Valley fever, is a fungal infection resulting from the inhalation of spores from the Coccidioides species (C. immitis and C. posadasii), native to arid areas of the Western Hemisphere. Coccidioidomycosis presents considerable health hazards and can be fatal. It affects between 206,000 and 360,000 individuals annually, leading to 700 to 1,100 fatalities in the United States alone. In response to these issues, extensive research has concentrated on therapeutic goals for this infectious disease. Nonetheless, more limited research has focused on the environmental detection of its causative fungi, which is crucial for forecasting treatment needs and formulating preventive strategies. …

"Alone I Can't, But Together We Can": A Photovoice Study To Explore Insights Of Assisted Outpatient Treatment (Aot) From Providers Working With Individuals With Serious Mental Illness (Smi)., Monica G. Urquieta

Open Access Theses & Dissertations

Assisted Outpatient Treatment (AOT) is a court-ordered mental health treatment program for individuals with SMI (bipolar disorder, major depressive disorder and schizophrenia) who have a history of noncompliance with treatment and are at risk of deteriorating or causing harm to themselves or others. This dissertation examined the perceptions and experiences of thirteen providers (lawyers, judges, case managers, psychiatrists, housing navigators, treatment guardians, nurse practitioners, therapists and peer support specialists with lived experience) on the AOT program for clients with SMI; and the environments that shape these perceptions, taking into account a system and community-based approach focusing on how the unique …

Screening Of A Diversity Of Legumes And Non-Legumes Forb Species At Five Strategic Locations Across Utah For The Development Of Smart Foodscapes, Surbhi Verma

All Graduate Theses and Dissertations, Fall 2023 to Present

Grass-dominated rangelands in the Western United States often lack sufficient protein for pregnant cows after grasses mature in mid- summer, leading ranchers to rely on expensive feed supplements such as protein cubes or alfalfa hay. The goal of this study was to screen 27 perennial legume and forb species with the potential to remain green into late summer and provide sufficient protein to supplement cows on grass-dominated rangeland. Three experiments were carried out to understand germination of species, plant establishment and persistence at five Utah locations, and agronomic characteristics. The seed of five hard-to-germinate species were studied for the ability …

Optimizing Nutrient Recycling To Achieve Zero–Discharge Management For Controlled Environment Agriculture, Noah James Langenfeld

All Graduate Theses and Dissertations, Fall 2023 to Present

Controlled environment agriculture (CEA) allows for human control of one or more environmental factors affecting crop production. Optimizing nutrient management in such systems allows for translation and predictions of sustainable management strategies in the field. These systems will be used to supply fresh food as public and private space agencies are planning to send humans to the Moon and Mars in the near future. Food resupply becomes increasingly difficult as the distance from Earth increases. Plants can be grown off-Earth as a food source, but their growth must be carefully managed to ensure long-term sustainability. I describe a model used …

Effects Of Plant Biostimulants On Onion Growth And Production Under Greenhouse And Field Conditions, Prakriti Nepal

All Graduate Theses and Dissertations, Fall 2023 to Present

The escalating impact of climate change on agricultural production underscores the need to investigate sustainable crop enhancement methods. This research explores the use of plant biostimulants to grow onion (Allium cepa L.) under varying environmental conditions. In the initial germination and greenhouse screening, seven biostimulants were tested on ‘Vaquero’ onion seeds: three bacterial products (Continuum, Spectrum DS, and Tribus Original), two mycorrhizal products (Mighty Mycorrhizae and Myco Apply), one seaweed extract product (Seaweed), and one product containing humic acid (Huma Pro 16). Mighty Mycorrhizae, Continuum, and Myco Apply supported faster germination, while seeds treated with Spectrum and Seaweed took …

Understanding The Impact Of Colloidal Calcium Phosphate On The Ph Variation In Cheddar Cheese During Early Stages Of Aging, Rachel Lindstrom

All Graduate Theses and Dissertations, Fall 2023 to Present

The Cheddar cheese industry has recently observed variation in the pH of their cheese during the early stage of storage. This variation may be due to the addition of the faster acid producing thermophilic starter culture Streptococcus thermophilus which was recently introduced into the Cheddar cheese making process. This starter culture may impact the calcium buffering properties of the cheese due to more retention of the insoluble calcium (INSOL Ca) within the cheese. To investigate this problem, we studied how insoluble calcium affects cheeses with pH ranging from 4.8 to 6.6 and found that INSOL Ca was positively correlated with …

Trends In The Prevalence Of Orofacial Clefts Among Hispanic Infants In The Rio Grande Valley Of Texas (1997-2018), Yossef Alsabawi, Aaron Dadzie, Kelsey Baker

School of Medicine Publications

Background Orofacial clefts (OFCs), including the cleft lip with or without cleft palate (CLP) and cleft palate alone (CP), represent significant congenital anomalies with implications for feeding, speech, and psychosocial development. The Rio Grande Valley (RGV) of Texas, a predominantly Hispanic region that faces socioeconomic and healthcare challenges, may have a distinct OFC profile compared to non-border counties (NBCs) of Texas. Methods Prevalence data with 95% confidence intervals for OFCs from 1997 to 2018 were obtained from the Texas Department of State Health Services (DSHS). Definitions provided by the DSHS were adhered to, including only definite diagnoses. Given the large …

Subclinical Atherosclerosis And Cardiovascular Events Among Patients With Colorectal Cancer, Julia A Levy, Adetunji T Toriola, Et Al.

2020-Current year OA Pubs

BACKGROUND: Prior studies have documented that patients with colorectal cancer (CRC) are at an increased risk of cardiovascular disease (CVD).

OBJECTIVES: To examine coronary artery calcium (CAC) as a marker of subclinical atherosclerosis and its association with major adverse cardiovascular events (MACE) in patients with CRC across the cancer treatment trajectory.

METHODS: Adults with newly diagnosed CRC were enrolled in the prospective ColoCare study from 2017 to 2024. CAC was measured from routine diagnostic computed tomography (CT) and positron emission tomography-CT scans at CRC diagnosis until 5 years post-diagnosis. Atherosclerosis was defined as the presence of CAC. We used multivariable-adjusted …

Participant Personal Characteristics And Adherence To Oral Capsules: A Secondary Analysis Of A Randomized Placebo-Controlled Trial Of Antenatal Probiotics, Lisa Hanson, Kathlyn Albert, Emily Malloy, Maharaj Singh, Mikala Kallay, Ava Brandt, Courtney Morris, Diana Kleber, Marie Forgie

College of Nursing Faculty Research and Publications

Background

Adherence to study interventions is critical to the conduct of randomized controlled trials (RCTs). The relationships between participant characteristics and intervention adherence are understudied in pregnant populations. The purpose of this study was to conduct a secondary analysis of adherence to study capsules in a double-masked, placebo-controlled RCT of a probiotic intervention to reduce antenatal Group B Streptococcus colonization, in relationship to participant characteristics.

Methods

We analyzed the relationship between capsule adherence rates and demographic characteristics among 81 RCT participants. Categorical variables were reported using counts and percentages, and continuous variables were expressed as means along with their standard …

The Feast And The Furious? The Effects Of Diet On Opioid Tolerance, Withdrawal, And Stress, Nina Marie Beltran

Open Access Theses & Dissertations

Introduction: Opioid drugs (e.g., morphine) are used medicinally for pain relief but can also lead to opioid use disorder (OUD). These medications are prescribed at a higher rate among individuals with obesity (who might consume high fat diets) than the general population. Further, previous work from our lab and others has demonstrated that eating a high fat diet enhances sensitivity of rats to other addictive substances, including stimulants. However, it is not known if dietary manipulations impact individual sensitivity to the effects of opioids. This dissertation systematically explored the effects of dietary manipulation on sensitivity to the effects of morphine. …

Racial And Ethnic Differences In Knowledge Of Gender-Affirming Care Among Community And Student Participants In The Bloom Transgender Health Education Program In The Paso Del Norte Region, 2022-2024, Tandra Ghosh

Open Access Theses & Dissertations

SUMMARY OF BACKGROUND AND SIGNIFICANCE: There is a noticeable lack of training and knowledge regarding gender-affirming care (GAC) among providers and within the general community. OBJECTIVE: Assess racial and ethnic disparities in knowledge of GAC among participants in BLOOM, a quasi-experimental transgender health education program in the Paso Del Norte region. HYPOTHESES: Among community and student participants at pre-survey, assess racial and ethnic differences in sociodemographic characteristics, preparedness, attitudes, and basic knowledge regarding LGBT clients/patients and GAC. METHODS: Secondary data among community (pre: 53; post: 14) and student (pre: 29; post: 17) BLOOM participants in 2022-2024 were used. Descriptive statistics …

American Academy Of Dermatology Acne Guidelines Of Care Versus Modern Skincare Trends, Natasha Barton, Patrick Mcclain, Monika Ziogaite, Robert P. Dellavalle, Cory A. Dunnick

Student Publications

Acne vulgaris remains one of the most prevalent dermatologic conditions worldwide, yet its management has become increasingly influenced by pop culture trends and consumer marketing. This review critically compares the American Academy of Dermatology (AAD) guidelines for acne treatment with the most popular skincare practices of the 2020s, including natural remedies, light therapy, and multi-step routines popularized through platforms like TikTok and Instagram. By examining the scientific evidence supporting AAD-recommended treatments, such as topical retinoids, benzoyl peroxide, and systemic therapies, and contrasting them with trending regimens that often lack clinical validation, this paper explores the widening gap between expert guidance …

Prevalence And Patterns Of Opioid Use In Chronic Pancreatitis, Anna Evans Phillips, Darwin L Conwell, Shuang Li, Jami L Saloman, Phil A Hart, Evan L Fogel, Santhi Swaroop Vege, Dana K Andersen, William E Fisher, Christopher E Forsmark, Stephen Pandol, Walter G Park, Mark D Topazian, Stephen K Van Den Eeden, Jose Serrano, Liang Li, Dhiraj Yadav

Faculty, Staff and Student Publications

Introduction: Opioids are used to treat pain in chronic pancreatitis (CP), but little is known about current use patterns. The aim of this study was to characterize the utilization of opioids and associations with clinical characteristics in adult patients with CP.

Methods: This cross-sectional analysis used baseline data from participants with definite CP enrolled in a cohort study in the United States (PROspective Evaluation of CP for EpidEmiologic and Translational StuDies). Data on demographics, pain medication use, healthcare utilization, disability, and pain patterns were systematically collected in case report forms while quality of life was assessed with patient-reported outcome instruments. …