Digital Commons Network^™

Correlations Between Social Media, Body Image Perceptions, And Disordered Eating Prevalence In Postpartum Women: A Pilot Cross-Sectional Study, Hannah Smith

Master's Theses

Postpartum women are a high-risk population for body dissatisfaction and disordered eating behavior due in part to the plethora of hormonal and physiological changes. Despite this, research examining this issue among postpartum women remains limited.

This pilot cross-sectional study investigated the relationship between social media use, body dissatisfaction, and disordered eating behavior among women up to 13 months postpartum. For this study, the following research questions were asked: Is high social media usage associated with higher levels of disordered eating among women up to 13 months postpartum? Is the association between social media usage and disordered eating mediated by a …

The Effect Of Dietary Strawberry Supplementation On Glycemic Control Factors In Overweight And Obese Postmenopausal Women With At-Risk Diabetes Mellitus Pathogenesis, Jennifer Herrera

Master's Theses

Glycemic control is directly related to type II diabetes mellitus (T2DM). As of 2023, 30.5 million Americans have T2DM, and this number only continues to increase exponentially across the world (“Facts & Figures,” n.d.). T2DM is only a precursor to fatal conditions including cardiovascular disease, the number one cause of death in the United States. Extensive research has revealed that strawberries, a high polyphenolic food, may pose positive effects on glycemic control biomarkers. This study aimed to investigate the effect of three servings of strawberries in the form of 39-g of freeze-dried strawberry powder (FDSP) for six weeks on glycemic …

Male Layer-Type Birds (Lohmann Brown Classic Hybrid) As A Meat Source For Chicken Pâtés, Nikolay Kolev, Desislav Balev, Stefan Dragoev, Teodora Popova, Evgeni Petkov, Krasimir Dimov, Surendranath Suman, Ana Paula Salim, Desislava Vlahova-Vangelova

Animal and Food Sciences Faculty Publications

The valorisation of underutilized male layer-type chickens offers a sustainable and ethically aligned opportunity for the poultry industry. This study evaluated the feasibility of male layer-type chicken meat in the production of chicken pâtés and compared the effects of different meat sources—commercial broiler (CP), and 5 (5wP) and 9-week-old (9wP) male layer-type chickens—on product quality during refrigerated storage using the general linear model with the Tukey–Kramer post-hoc test. Pâtés made from 5wP meat exhibited the most favourable technological properties, including the lowest (p < 0.05) total expressible fluid (TEF), highest (p < 0.05) water retention (TEF_Water), and lowest (p < 0.05) fat content (TEF_Fat) than CP and 9wP indicating superior emulsion stability. The 5wP …

Psychometrics Of Inflammatory Back Pain Criteria In The Us Population, Mark C Hwang, Seokhun Kim, Shervin Assassi, Alexis Ogdie, Michael H Weisman, John Reveille, Charles Green

Faculty, Staff and Student Publications

Objectives: Evaluation of axial spondyloarthritis relies on capturing various inflammatory back pain (IBP) features represented in different criteria. These criteria are likely to be interpreted differently across demographic subpopulations. We examined IBP criteria dimensionality and differential item functioning (DIF) among different age, gender, and race groups using a nationally representative sample.

Methods: We utilised the National Health and Nutrition Examination Survey (NHANES) 2009-2010 dataset, a US nationally representative data collection with demographic weighting. The Arthritis Questionnaire (ARQ) within NHANES included questions from published Calin, European Spondyloarthropathy Study Group, and Berlin criteria (8a and 7b). Confirmatory factor analysis (CFA) was performed …

Time To Weight Plateau With Tirzepatide Treatment In The Surmount-1 And Surmount-4 Clinical Trials, Deborah B Horn, Scott Kahan, Rachel L Batterham, Dachuang Cao, Clare J Lee, Madhumita Murphy, Sylvia Gonsahn-Bollie, Farai Chigutsa, Adam Stefanski, Julia P Dunn

Faculty, Staff and Student Publications

The rate of weight reduction during obesity treatment declines over time and eventually reaches a weight plateau. We investigated factors associated with time to weight plateau (TTWP) in tirzepatide-treated participants with obesity or overweight in a post-hoc analysis of SURMOUNT-1 and SURMOUNT-4 trials. Participants adherent to tirzepatide treatment and achieving ≥5% weight loss by primary endpoint (week 72 SURMOUNT-1; week 88 SURMOUNT-4) were included. Weight plateau was defined as a weight change < 5% over a 12-week interval and all subsequent 12-week intervals. TTWP was time from randomization to the start of the first 12-week interval. Association between baseline characteristics and TTWP was assessed. Overall, 1438 participants in SURMOUNT-1 and 259 in SURMOUNT-4 were included. Across BMI categories (overweight, class I, II, and III), median TTWP in SURMOUNT-1 was 24.3, 26.0, 36.1, and 36.1 weeks, respectively (p < .05, class II and III vs. overweight). By week 72, 90.2%, 88.9%, 87.6%, and 87.8% of participants in SURMOUNT-1 had reached a weight plateau across respective BMI categories [Correction added on 22 January 2025, after first online publication: The "72%" has been changed to "72" in this version.]. Higher doses of tirzepatide (10/15 mg), younger age, and female sex were more likely to reach a weight plateau later. Results in SURMOUNT-4 were similar. In this post-hoc analysis, most participants reached a weight plateau by week 72. Higher doses of tirzepatide, younger age, and female sex were associated with a longer TTWP. Further research into modifiers of weight reduction phases with tirzepatide may inform treatment decisions for its use in chronic weight management. Clinical Trial Registration: ClinicalTrials.gov, identifiers NCT04184622 (SURMOUNT-1) and NCT04660643 (SURMOUNT-4), available at http://www.clinicaltrials.gov/.

A Developmental Texture Framework For Food Texture Progression: Implications For Feeding Development, Oral Motor Skills, And Pediatric Feeding Disorder, Amy L. Delaney, Sarah Staskiewicz, Suzanne Evans Morris, Sarah Smith-Simpson, Praveen S. Goday

Speech Pathology and Audiology Faculty Research and Publications

The introduction of food textures in a child's first 2 years of life plays a vital role in growth, nutrition, and feeding development. However, the absence of a standardized texture framework for studying texture progression limits both pediatric feeding research and the ability to diagnose pediatric feeding disorder (PFD) based on age-appropriate expectations. To address this gap, authors Delaney and Goday proposed data sharing from the Nestlé Feeding Infant-Toddler Study (FITS) to explore texture progression and define age-appropriate texture expectations. In response, Nestlé assembled a multidisciplinary panel of feeding experts to create standardized textures but did not provide financial or …

Breakthrough Infection And Death After Covid-19 Vaccination: A Physics Perspective, Seyed Ali Reza Mortazavi, Abdollah Jafarzadeh, Abdolkarim Ghadimi-Moghadam, Seyed Mohammad Javad Mortazavi, Masoud Haghani, Ali Ghadimi-Moghadam, Lembit Sihver

Informatics and Engineering Systems Faculty Publications

The largest universal immunization in history has occurred as a result of the COVID-19 pandemic. The developed COVID-19 vaccines have been shown to provide protection against severe forms of COVID-19 by inducing anti-spike neutralizing antibodies. It has been found that individuals who have not been vaccinated against COVID-19 were more likely to contract the virus during a period when the Delta variant was dominant, as compared to those who have received the complete dose of the vaccine, irrespective of the variant. However, there is no notable disparity in the likelihood of hospitalization, requirement for mechanical ventilation, or mortality between the …

Status And Distribution Of Diseases Caused By Phytoplasmas In Africa, Shakiru Adewale Kazeem, Agnieszka Zwolińska, Joseph Mulema, Akindele Oluwole Ogunfunmilayo, Shina Salihu, Joy Oluchi Nwogwugwu, Inusa Jacob Ajene, Justina Folasayo Ogunsola, Adedapo Olutola Adediji, Olubusola Fehintola Oduwaye, Kouamé Daniel Kra, Mustafa Ojonuba Jibrin, Wei Wei

All Peer-Reviewed Publications

Phytoplasma (“Candidatus Phytoplasma” species) diseases have been reported globally to severely limit the productivity of a wide range of economically important crops and wild plants causing different yellows-type diseases. With new molecular detection techniques, several unknown and known diseases with uncertain etiologies or attributed to other pathogens have been identified as being caused by Phytoplasmas. In Africa, Phytoplasmas have been reported in association with diseases in a broad range of host plant species. However, the few reports of Phytoplasma occurrence in Africa have not been collated together to determine the status in different countries of the continent. Thus, this paper …

One Health Interventions And Challenges Under Rural African Smallholder Farmer Settings: A Scoping Review, Evanson R. Omuse, Honest Machekano, Bonoukpoè M. Sokame, Daniel M. Mutyambai, Thomas Dubois, Sevgan Subramanian, Frank Chidawanyika

All Peer-Reviewed Publications

The global human population is rapidly increasing, escalating interactions of people, animals and the environment. This has led to more convoluted health challenges, for which African smallholder farmers bear the brunt. The One Health (OH) approach recognises the interconnectedness of these health challenges and thus follows a transdisciplinary approach involving diverse stakeholders to address them. Although there have recently been global concerted efforts and studies on OH, an information gap exists in Africa, particularly regarding smallholder farmers and their needs. Additionally, evaluation frameworks and outcome metrics for OH initiatives are still unclear. Thus, this study was conducted to critically map …

A Virtual Wellness Program To Enhance Well-Being For Pediatric Oncology Staff During The Covid-19 Pandemic, Karen M Moody, Maria Chang Swartz, Zachary Gresham, Martha Askins, Laura Cahalan, Christine Geistkemper, Amy Heaton, Ruitao Lin, Melissa Melo, Alakh Rajan, Madeline Smith, Priti Tewari, Keyana Williams, Cheng-Han Yang, Rhonda Robert

Faculty, Staff and Student Publications

In response to the COVID-19 global health crisis and mandated social isolation, Pediatric leadership at MD Anderson Children's Cancer Hospital was concerned for the psychological impact on its workforce and encouraged wellness programming. A grassroots wellness taskforce was assembled for the Division of Pediatrics. The task force's primary mission was to promote the well-being of clinicians and non-clinical staff members through a broadly accessible, sustainable, and effective virtual wellness program. Guided by the Stanford Model for Professional Fulfillment, a virtual program entitled, "Weekly Wellness Webex" for Pediatrics staff was launched. Weekly Wellness Webex is a 1-hour live-streamed program with varied …

June 2025, Swosu Bulldog Wellness Committee

SWOSU BULLDOG WELLNESS

June 2025 Newsletter brought to you by the Bulldog Wellness Committee

You can do it! It's easy to eat more fruit and vegetables with this Fruit and Vegetable Guide. It offers practical tips that don’t require big changes to the way you or your family eats. The American Heart Association has a handy guide for ideas and recipes.

The Impact Of Nicu Death On Bereaved Mothers, Jennie Terranova

University Honors Theses

Infant loss in the United States occurs 5.6 per 1,000 live births. This paper examines risk factors that contribute to neonatal death. Prematurity is a risk factor for NICU admission. A portion of premature babies receiving care in the NICU will die. The stressful nature of the NICU has been studied widely in journals. The impact of NICU death on hospital staff and bereaved parents has been studied less. Mortality studies suggest that bereaved mothers are at a high risk of dying within the first 5 years after their child has died. Despite the frequency of maternal death post-child loss, …

Gianjara's Ribs: The Ecosystem, Body, Animalia, And Politic, Linus Gomez Ellis

University Honors Theses

This work is a series of four six foot tall full-body portraits of people, which are displayed alongside an actual, physical item or garment present in the associated painting. The purpose of this is to blur the line between the fiction of the individuals depicted and the viewer. By creating "portals" through which to view them as equals in stature, Linus Gomez Ellis is taking something that can be seen in the ecosystem of this fiction and making it into an objective reality. The most enduring, well preserved, and eternal pieces of history and anthropology are tall tales. This ecosystem, …

Surveying Management Strategies For Pediatric Autoimmune Hepatitis, Lillie Baca

University Honors Theses

Pediatric autoimmune hepatitis (PAIH) is a long-term condition that requires ongoing treatment and regular monitoring. It is characterized by its elevation of liver enzymes, interface hepatitis, and the specific presence of circulating autoantibodies. There is a general lack of consensus on appropriate measures of diagnostic criteria, treatment medication, and beneficial practices for monitoring the disease. The existing literature contains several subtle discrepancies that challenge a practitioner's judgement for care management of children with autoimmune hepatitis. This study is a retrospective chart review aimed at understanding the current diagnostics, treatment, and long-term management strategies of PAIH at a single center. Also, …

The Necessity Of Improved Pica Assessment Tools And Screening Practices For Harm Reduction, Deborah Arakelian

University Honors Theses

Pica disorder refers to the consumption of non-food items, and has historically been understudied. Dangerous medical complications often arise as result of this behavior, making this a critical area of continued research. This paper reviews literature on the prevalence of pica disorder, as well as its etiologies and risk factors with the intention to identify at-risk groups who would benefit from increased screening. The current assessment tool used for screenings and research is vague and insufficient, and the development of a more comprehensive tool is critical to reduce harm. This paper discusses what should be included in an improved questionnaire, …

Not Just An Ad: Exploring Exposure, Persuasion Knowledge, And Health Misinformation On Social Media, Danielle Murray

University Honors Theses

This study explores how exposure to sponsored health and fitness content on social media influences users' perceptions of influencer motivation and belief in health-related misinformation. Drawing on parasocial interaction (PSR), attribution theory, and influencer marketing research, this study investigates two hypotheses: that frequent exposure to branded content is positively associated with (1) perceptions of influencers as commercially motivated and (2) belief in pseudoscientific health myths. A cross-sectional online survey (N = 104) was conducted using convenience sampling of adult social media users. Results partially supported the first hypothesis: exposure frequency was positively correlated with recognition of persuasive intent, but …

Do Government Benefit Programs Reduce Child Labor?: Causal Evidence From The Midday Meal Scheme In India, Vardaan Chawla, Tomoki Fujii, Arpita Khanna, Ray Rohan

Research Collection School Of Economics

This study evaluates the impact of the midday meal program in India on the prevalence of child labor for upper primary school going children. The staggered implementation of the largest school feeding program in the world across states provides exogenous variation in exposure. Using the nationally representative National Sample Survey Office (NSSO) data, we find that exposure to the program reduced prevalence of child labor by 47 percent relative to children in never-treated states, with no significant difference in impact between boys and girls. The effects were primarily driven by a decline in household labor supply, especially performance of household …

Bile Acid Regulation Of Xenobiotic Nuclear Receptors On The Expressions Of Orosomucoids In The Liver, Ji Ho Suh, Inyoung Cheon, Hyun-Jung Jung, Sung Ho Lee, Mi Jeong Heo, Matthew Deberge, Clavia Ruth Wooton-Kee, Kang Ho Kim

Children’s Nutrition Research Center Staff Publications

The constitutive androstane receptor (CAR) and pregnane X receptor (PXR) are xenobiotic nuclear receptors activated by various xenobiotics, drugs, hormones, and bile acids (BAs). Upon activation, these nuclear receptors play critical roles in regulating systemic energy homeostasis. However, precise mechanisms through which CAR and PXR influence systemic metabolism remain incompletely understood. Here, we investigated the impact of CAR and PXR on the liver-secreted hormone (i.e., hepatokine) expressions in response to BA stress such as cholic acid (CA) feeding. Our analysis revealed that several BA-activated genes, including the well-known CAR/PXR target, aldo-keto reductase family 1, member B7 (Akr1b7 …

Changes In The Fxr-Cistrome And Alterations In Bile Acid Physiology In Wilson Disease, Clavia Ruth Wooton-Kee, Hari K Yalamanchili, Islam Mohamed, Manal Hassan, Kenneth D R Setchell, Monica Narvaez Rivas, Ayse K Coskun, Vasanta Putluri, Nagireddy Putluri, Prasun Jalal, Michael L Schilsky, David D Moore

Children’s Nutrition Research Center Staff Publications

Background: Wilson disease (WD) is an autosomal recessive disorder that results in excessive hepatic copper, causing hepatic steatosis, inflammation, fibrosis, cirrhosis, and liver failure. Previous studies have revealed dysregulation of many farnesoid X receptor (FXR) metabolic target genes in WD, including the bile salt exporter pump, the major determinant of bile flow.

Methods: We tested the hypothesis that the FXR-cistrome is decreased in Atp7b-/- mice in accord with dysregulated bile acid homeostasis.

Results: FXR binding within Atp7b-/- mouse livers displayed surprising complexity: FXR binding was increased in distal intergenic regions but decreased in promoter regions in Atp7b-/- versus wild-type mice. …

Periodontal Diseases In Africa, Mojisola Olujitan, Patricia O. Ayanbadejo, Kehinde Umeizudike, Afolabi Oyapero, Christopher Okunseri, Azeez Butali

School of Dentistry Faculty Research and Publications

Periodontal diseases, a group of complex conditions marked by an excessive immune response and periodontal tissue destruction, are a global health concern. Since 1990, the incidence of these diseases has doubled, with Western sub-Saharan Africa experiencing the highest burden. Accurate diagnosis and case identification are crucial for understanding the etiology, features of disease, research, treatment and prevention. Modern perspectives on periodontal disease classification are based on commonality among those affected. However, current literature is often plagued by methodological inconsistencies and focused on disease mechanisms in European populations. Health inequalities in low- and middle-income countries (LMICs) are exacerbated by these challenges, …

Emulating Empire: Washington’S Preoccupation With British Counterinsurgency In Malaya And U.S. Commitment To Vietnam, Wen-Qing Ngoei

Research Collection College of Integrative Studies

This essay examines how Washington’s deep preoccupation with the British-Malayan counterinsurgency tactics–tactics that routed the guerilla fighters of the Malayan Communist Party–shaped US commitment to Vietnam. This US preoccupation, stoked by Britain’s (and Malaya’s) promotion of their counterinsurgency knowledge to US leaders, also influenced the lessons that US analysts and thinkers absorbed from the United States’ defeat in Indochina. Most studies of British-Malayan counterinsurgency and its connection to the Vietnam War fixate upon debating the relevance of the former to the latter and how this bears on US failures in Indochina. However, this essay focuses on the understudied fervor with …

A Standardized Bathing Protocol To Prevent Central Line–Associated Bloodstream And Methicillin-Resistant Staphylococcus Aureus Infections, Lindsy L. Phillips

Electronic Theses and Dissertations

Central line–associated bloodstream infections (CLABSIs), including methicillin-resistant Staphylococcus aureus (MRSA) infections, in medical–surgical inpatients increase mortality, length of stay, and readmissions. In this project, the investigator sought to decrease CLABSIs and MRSA infections through quality improvement by implementing a standard chlorhexidine gluconate (CHG) bathing process. An urban hospital in the Midwestern United States experienced more CLABSIs and MRSA infections than expected in 2024. This unit had a standardized infection ratio of 1.4, with three CLABSIs rather than the 2.1 predicted. Also, they had 10 hospital-acquired MRSA isolates, which was higher than the 3.3 average of the other medical–surgical units. The …

Exploring New Mexico 4-H Volunteers’ Acceptance And Use Of Technology: A Qualitative Approach, Kayla Dawn Hinrichs

Electronic Theses and Dissertations

Integrating technology into youth development programs like 4-H is increasingly vital for enhancing communication, education, and engagement. However, technology adoption among 4-H volunteers remains inconsistent. This qualitative study explored the barriers to technology adoption among New Mexico 4-H volunteers. The researcher aimed to understand the factors influencing their willingness and ability to integrate digital tools into their volunteer roles. Guided by Rogers’s (2003) diffusion of innovation theory and framed by Creswell and Poth’s (2024) qualitative research design, this study employed semistructured interviews with a purposive sample of 4-H volunteers across the state. Following Braun and Clarke’s (2006) six- phase approach, …

Weight Recidivism Post-Bariatric Surgery: A Lifestyle Modifications Educational Intervention, Kimeshia N. Johnson

Electronic Theses and Dissertations

Weight recidivism after bariatric surgery is a frustrating phenomenon for bariatric surgery patients and healthcare professionals. A 90-day lifestyle modification intervention for patients at least 18 months postsurgery was performed in the primary care setting to determine if a structured program could promote or maintain weight loss. The intervention aimed to investigate if participation in a structured lifestyle modification program would impact the body mass index of bariatric patients at least 18 months postsurgical intervention. In coordination with a nutritionist specializing in addiction and obesity education, a booklet detailing the guidelines for a 12-week program was provided to 41 bariatric …

‘Making A Positive Environmental Impact’: Exploring The Role Of Volunteering At A Campus Community Garden, Dina Izenstark, Barbara Ann Boone

Faculty Research, Scholarly, and Creative Activity

Promoting sustainability in higher education is a social and environmental imperative. This paper explores how and why volunteering at a campus community garden (CCG) can serve as a unique context for promoting sustainability. Twenty-five undergraduate students between the ages of 18 and 27, who had volunteered at a campus garden, participated in individual semi-structured interviews. A majority of participants identified as female (80%) and Asian American (52%). Using reflexive thematic analysis, we first found students were motivated to volunteer for personal and academic reasons as well as to learn more about gardening. Childhood gardening experiences influenced participants’ re-engagement as adults. …

Cardiac Autonomic Dysfunction In Patients With Cancer: Exploring The Role Of Physical Exercise, Anita Borsati, Linda Toniolo, Christian Ciurnelli, Francesco Bettariga, Silvia Teresa Riva, Paolo Frada, Lorenzo Belluomini, Ilaria Trestini, Daniela Tregnago, Jessica Insolda, Marco Sposito, Federico Schena, Michele Milella, Robert U. Newton, Sara Pilotto, Alice Avancini

Research outputs 2022 to 2026

Purpose: Cardiovascular diseases are a leading cause of non-cancer mortality among patients with cancer, with cardiac autonomic dysfunction identified as a significant predictor of future cardiovascular conditions. Despite the importance of autonomic dysfunction as a prognostic marker being well-established in healthy individuals and other chronic conditions, its role in patients with cancer remains underexplored. This narrative review aims to synthesize existing literature on the role of cardiac autonomic dysfunction in patients with cancer and explore the potential of physical exercise as a non-pharmacological intervention to modulate the autonomic nervous system positively. Methods: This review examines methods for assessing cardiac autonomic …

Exposure To Different Motives Of Scientists Moderates Responses To Scientific Consensus: The Case Of Cultured Meat, Kimin Eom, Bryan Kwok Cheng Choy

Research Collection School of Social Sciences

This research examines how exposure to different motives of scientists affects the impact of scientific consensus on public attitudes toward cultured meat. While scientific consensus on the safety of cultured meat generally increased positive attitudes toward it, this effect depended on information about scientists’ motives. Exposure to information about scientists’ financial motives weakened the positive effect of scientific consensus because it undermined trust in scientists. Information about scientists’ prosocial motives did not influence the scientific consensus effect. These findings suggest that perceived motives can shift trust in experts, thereby affecting the influence of experts on public attitudes.

Cysteine Depletion Triggers Adipose Tissue Thermogenesis And Weight Loss, Aileen H Lee, Irina Shchukina, Prabhakar Sairam Andhey, Maxim N Artyomov, Et Al.

2020-Current year OA Pubs

Caloric restriction and methionine restriction-driven enhanced lifespan and healthspan induces 'browning' of white adipose tissue, a metabolic response that increases heat production to defend core body temperature. However, how specific dietary amino acids control adipose thermogenesis is unknown. Here, we identified that weight loss induced by caloric restriction in humans reduces thiol-containing sulfur amino acid cysteine in white adipose tissue. Systemic cysteine depletion in mice causes lethal weight loss with increased fat utilization and browning of adipocytes that is rescued upon restoration of cysteine in diet. Mechanistically, cysteine-restriction-induced adipose browning and weight loss requires sympathetic nervous system-derived noradrenaline signalling via …

Vitamin K: Metabolism, Genetic Influences, And Chronic Disease Outcomes, Montana Dupuy, Nicola P. Bondonno, Pratik Pokharel, Allan Linneberg, Itamar Levinger, Carl Schultz, Jonathan M. Hodgson, Marc Sim

Research outputs 2022 to 2026

Vitamin K refers to a group of lipid-soluble vitamins that exist in two natural isoforms; phylloquinone (PK, vitamin K1) and menaquinones (MKs, vitamin K2). Phylloquinone, the primary dietary source, is found abundantly in green vegetables and plant oils. Menaquinones (MK-4 through MK-13) are synthesized by anaerobic bacteria and may be obtained through the diet from fermented foods and animal products (e.g., meats, dairy and eggs). Originally recognized for its role in blood coagulation, vitamin K is an essential cofactor for the posttranslational carboxylation of vitamin K-dependent proteins (VKDPs), which are implicated in various physiological processes including; blood coagulation, calcium homeostasis, …

Baseline Habitual Dietary Nitrate Intake And Alzheimer's Disease Related Neuroimaging Biomarkers In The Australian Imaging, Biomarkers And Lifestyle Study Of Ageing, Anjana Rajendra, Nicola P. Bondonno, Kevin Murray, Liezhou Zhong, Stephanie R. Rainey-Smith, Samantha L. Gardener, Lauren C. Blekkenhorst, Vincent Doré, Victor L. Villemagne, Simon M. Laws, Belinda M. Brown, Kevin Taddei, Colin L. Masters, Christopher C. Rowe, Ralph N. Martins, Jonathan M. Hodgson, Catherine P. Bondonno

Research outputs 2022 to 2026

Background: Dietary nitrate, as a nitric oxide (NO) precursor, may support brain health and protect against dementia. Objective: Our primary aim was to investigate whether dietary nitrate is associated with neuroimaging markers of brain health linked with Alzheimer's disease (AD). Participants: Study participants were cognitively unimpaired individuals from the Australian Imaging, Biomarkers and Lifestyle Study of Ageing (AIBL) who had β-amyloid positron emission tomography (PET) scans (n = 554) and magnetic resonance imaging (MRI) scans (n = 335) and had completed a Food Frequency Questionnaire at baseline. Methods: Source-specific nitrate intakes were estimated using comprehensive nitrate food composition databases. Rates …