Digital Commons Network^™

The Immunological Benefits Of Breast Feeding (Review Article), Ahmed Al-Harbi, Asmaa Shetawi

Iraqi Postgraduate Medical Journal

Breast feeding (BF) provides infants with the most suitable nutrients from birth tell weaning. The major part of mother breast milk (MBM) is water in which the other components dissolve. These components include nutrients and immune factors. The concentration of these components varies by time after delivery. Breast milk even provides infants with various types of bacterial species that contribute for development of infant microbiota.Components that are regarded important for shaping of infant immune response include different factors. MBM contains oligosaccharides which are associated with guts defenses, cytokines that participate in inflammation and immune cells activation, immunoglobulins that arm infant’s …

Assessment Of Preoperative Factors In Relation With Difficulty Of Laparoscopic Cholecystectomy, Ahmed Nayyef, Hayder Alkawaz

Iraqi Postgraduate Medical Journal

IntroductionLaparoscopic cholecystectomy is the gold standard for treatment of gallbladder diseases It is relatively a simple and quick procedure, but it can be difficult, and needs special instruments and an experienced surgeon. Moreover, in specific situations, conversion from laparoscopic to open approach is still required. However, identifying the preoperative patient-related factors, and anticipating the need to convert from laparoscopic cholecystectomy to open surgery can help identifying high-risk patients and redefine the surgical strategy needed Aim:Assessing laparoscopic cholecystectomies, by identifying the preoperative factors that predict the difficulty of laparoscopic cholecystectomy.Patients and MethodA prospective cross-sectional study conducted in Al Yarmouk Teaching Hospital …

Inhibition Of Srebp-1c Rescues Hepatic Cyp7b1 Expression And Bile Acid Synthesis In Malnourished Mice, Xiaoyang Wan, Krishnakant G Soni, Jong Min Choi, Sun Yun Jung, Margaret E Conner, Geoffrey A Preidis

Faculty, Staff and Students Publications

Malnutrition decreases intestinal bile acids, resulting in inefficient nutrient absorption and impaired catch-up growth. Mechanisms by which bile acid depletion occurs in malnutrition are unknown. Using a mouse model of early-life malnutrition, we explored bile acid homeostasis, focusing on transcriptional repression of CYP7B1, a rate-limiting enzyme in the alternative pathway of bile acid biosynthesis, by SREBP-1c, a master regulator of lipid metabolism. Mice were maintained on a low-protein low-fat or isocaloric control chow until eight weeks of age when livers were harvested for proteome profiling, western blot, RT-qPCR, and chromatin immunoprecipitation. Cultured hepatocytes and mice were treated with the SREBP-1c …

Metabolomic Data May Support The Development Of Personalized Nutrition Approaches To Type 2 Diabetes Management, Danielle J Lee, Shragvi Balaji, Jerome I Rotter, Alexis C Wood

Faculty, Staff and Students Publications

Diet is a major modifiable risk factor for type 2 diabetes (T2D), and suboptimal diets continue to contribute substantially to the population burden of T2D. Personalized nutrition proponents argue that specializing recommendations to interindividual differences in diet-health relationships will yield reductions in disease risk. However, how to personalize diet, and to whom, to reduce T2D risk remains unclear. Metabolites offer promise in this respect, as they capture (in part) dietary intake after the processes of digestion, processing, and absorption. The incorporation of metabolite data into diet-health studies therefore offers the opportunity to examine how the effects of food on the …

Quality Of Life Outcomes Following Total Temporomandibular Joint Replacement: A Systematic Review Of Long-Term Efficacy, Functional Improvements, And Complication Rates Across Prosthesis Types, Luis Eduardo Almeida, Samuel Zammuto, Louis G. Mercuri

School of Dentistry Faculty Research and Publications

Introduction:

Total temporomandibular joint replacement (TMJR) is a well-established surgical solution for patients with severe TMJ disorders. It aims to relieve chronic pain, restore jaw mobility, and significantly enhance quality of life. This systematic review evaluates QoL outcomes following TMJR, analyzes complication profiles, compares custom versus stock prostheses, explores pediatric applications, and highlights technological innovations shaping the future of TMJ reconstruction.

Methods:

A systematic search of PubMed, Embase, and the Cochrane Library was conducted throughout April 2025 in accordance with PRISMA 2020 guidelines. Sixty-four studies were included, comprising 2387 patients. Results: Primary outcomes assessed were QoL improvement, pain reduction, and …

Impact Of The Adjunctive Use Of Omega-3 In Periodontitispatients With Diabetes On Local And Systemic Chemerin Levels:A Randomized Clinical Trial, Dalia Ghalwash, Ahmed M. Ammar, Ayman El-Gawish, Ahmed Hamdy

Dentistry

Aims: The present study aspired to evaluate the impact of the adjunctive use of omega-3 with nonsurgical periodontal therapy onclinical parameters as well as local and systemic chemerin levels as a marker of cardiovascular disease risk in periodontitis patientswith diabetes.Methods: This randomized clinical trial was performed on thirty periodontitis patients with type II diabetes divided into two equalgroups, both treated by nonsurgical periodontal treatment with the adjunctive use of daily 1000 mg Omega-3FAs in group I onlyfor 6 months. Patients were reexamined after 2 weeks (baseline), 3, and 6 months for recording the clinical parameters as follows:plaque index (PI), gingival …

The Effect Of Individual Variation On Epidemiological Dynamics: From Super-Spreaders To Landscapes Of Risk, Alexis Shannon Beagle

Dissertations and Doctoral Documents, University of Nebraska-Lincoln, 2023–

Individuals that make up a population always display some level of variation between members. At the smallest scale, individuals always maintain genetic variation, but variation continues to arise at other scales of biological organization from physiological or immunological variation within individuals to variation in behavior between individuals that can be both genetically and environmentally mediated. The role of individual variation is particularly important in the context of infectious diseases because there is strong evidence that infections are highly heterogenous, indicating that patterns of individual variation drive a significant portion of the epidemiological patterns we observe. Individual variation leads to heterogeneity …

Open Repository @ Binghamton Monthly Additions And Top Downloads - June 2025, Caitlin Holton

Library Created Resources

Newly added work in the Open Repository @ Binghamton (ORB) from 6/1/2025-6/30/2025. Top downloads from same time frame.

Through A Mother's Eyes: The Psychology Of Color, Katie Kutz

Theses

This project investigates the intersection of color psychology, maternal experience, and visual perception through a series of five artworks. Using a qualitative methodology, this project draws upon interdisciplinary research such as neuroscience, marketing, art history, and personal experiences as a mother. This work explores how sensory changes during pregnancy and postpartum influence the emotional perception of color, and how this can be represented in art. Inspired by artists that have explored the theme of motherhood such as Mary Cassatt, Käthe Kollwitz, Paula Modersohn-Becker, Jenny Saville, and Alice Neel, this project uses an emotionally charged approach to depicting motherhood. Color changing …

Psychosocial Supports For The Physical And Mental Health Of Youth With Autism And Other Neurodevelopmental Disabilities., Melissa Campbell, Elizabeth Hastings, Paige Mcardle, Darren Olsen, Kathryn Benton, Cy Nadler

Manuscripts, Articles, Book Chapters and Other Papers

One in six youth has a neurodevelopmental disability (NDD), and autism diagnostic rates continue to rise. Before and after a diagnosis, families need trusted sources of guidance to navigate co-occurring medical and psychological conditions, and to manage unique stressors including transition to adulthood. However, medical professionals from all specialty areas struggle to identify resources to support the complex psychosocial and healthcare needs of these patients and their families. This primer on psychosocial supports for youth with autism will explore the major mental and physical health stressors faced by affected youth and families, and discuss opportunities for primary care and other …

Volumetric And Diffusion Tensor Imaging Abnormalities Are Associated With Behavioral Changes Post-Concussion In A Youth Pig Model Of Mild Traumatic Brain Injury., Sanjida Islam, Alesa Netzley, Chenyang Li, Jiangyang Zhang, Bianca Dávila-Montero, Ana Vazquez, Shaun Subbaiah, Avner Moeded, Kirk Munoz, Aimee Colbath, Jie Huang, Ricardo Mejia-Alvarez, Jane Manfredi, Galit Pelled

Manuscripts, Articles, Book Chapters and Other Papers

Mild traumatic brain injury (mTBI) caused by sports-related incidents in children and youth often leads to prolonged cognitive impairments but remains difficult to diagnose. In order to identify clinically relevant imaging and behavioral biomarkers associated concussion, a closed-head mTBI was induced in adolescent pigs. Twelve (n = 4 male and n = 8 female), 16-week old Yucatan pigs were tested; n = 6 received mTBI and n = 6 received a sham procedure. T1-weighted imaging was used to assess volumetric alterations in different regions of the brain and diffusion tensor imaging (DTI) to examine microstructural damage in white matter. The …

The Pediatric Experience Collaborative: Paving The Way In Pediatric Experience., Lauren Hamilton, Trenton House, Taylor B. Sewell, Harris Baden, Brianna Combs, Sara L. Toomey, Shehzad Saeed, Jana Rojas, Molly Warneke, Maureen Hoff, Andréa Aken'ova, Lisa Rubino, Dana Ileana Williams, Samuel P. Hanke

Manuscripts, Articles, Book Chapters and Other Papers

Positive patient experience is associated with improved patient outcomes, but efforts to improve patient experience are often underprioritized, especially with respect to pediatric care. To address this challenge, leaders at several US children's hospitals established the Pediatric Experience Collaborative (PEC) in 2016 to leverage their collaboration and scale to optimize patient, family, and provider experiences. Since then, the PEC has steadfastly incorporated the patient and family perspective in all its endeavors (e.g., installing a family member as one of the organization's co-chairs); has created both structured opportunities and unstructured opportunities for learning and connection; and has embarked on multi-institutional research …

Sharksrx Newsletter Summer 2025, Nova Southeastern University

NSU Sharks Rx

No abstract provided.

Step By Step, Patrick M. Filanowski, Jeremy A. Steeves, Emily Slade

Biostatistics Faculty Publications

Background/Objectives: Although public health organizations encourage family walking, no studies have examined children’s physical activity and enjoyment during outdoor parent–child walks. This study addresses those gaps by examining children’s moderate-to-vigorous physical activity (MVPA) and enjoyment during outdoor walks with their parents, along with parental barriers and their relationship with parent’s self-efficacy and co-activity minutes. Methods: Fifty parent–child dyads (children aged 6–12 years) completed 10 min, self-paced outdoor walks while wearing waist-worn ActiGraph monitors. Parents reported perceived barriers to walking outdoors with their child and self-efficacy for supporting their child’s daily physical activity. Results: Children reported high enjoyment (mean = 5.1 …

The Evaluation Of Anti-Factor Xa Levels In Hospitalised Patients Receiving Low Molecular Weight Heparin (Lmwh): A Prospective Study, Tandzile Thandwayinkosi Simelane

Master of Medicine in Clinical Pathology

Background 

Patients admitted to the hospital have been reported to have coagulation abnormalities due to various factors including immobilisation, preexisting disease, and current illness. The overall incidence of venous thromboembolism (VTE) in critically ill patients varies from 15% to well over 50%, even with the use of prophylactic measures in most patients. Low molecular weight heparin (LMWH) and unfractionated heparin (UFH) are the recommended drugs for VTE prophylaxis in inpatient care. Although not standardly recommended, the laboratory can offer monitoring of anti-Factor Xa using the gold standard method of chromogenic anti-Factor X assay. The anti-Factor Xa levels are notably affected …

Chronic Illness Education 2025: Prevention And Management, Alyusuf Elnaggar, Brenna Hairston, Carly Ghanem, Fatima Bhatti, James Wairagu, Lucy Yu, Najeeb Baig, Ryan Murphy

Patient Education Projects

No abstract provided.

Chronic Illness Education 2025: Risk Factors And Prevention Of Cardiovascular Disease, Christopher Matti, Clayton Kramm, Ghala Alhasan, Hadi Elmenini, Julia Miller, Maxine Kugelmas, Moshood Osinusi, Nievalinda Strong

Patient Education Projects

No abstract provided.

Investigating The Ecology Of The Homeless Court: The Promise Of Quasi-Experimental And Statistical Learning Methods, Dylan Wong

Theses and Dissertations

Interactions with the legal system are a crucial factor in maintaining homelessness. Difficulties in addressing legal issues are barriers to accessing services and finding employment and housing. Across the United States, the homeless court is an emerging legal program that has been developed to break this cycle, but they appear to face numerous capacity and coordination problems. Few empirical and systematic investigations have been conducted on homeless court programs. Further, previous studies of homeless courts focus their process and outcome measures on the priorities of the legal system. An investigation into the ecology, or environmental context, of homeless persons would …

Knowledge, Attitudes, And Practices Of Healthcare Workers Regarding Early Childhood Development: A Mixed-Methods Study At Secondary Care Maternal And Child Care Hospitals In Karachi, Pakistan, Sarosh Hirani, Shelina Bhamani, Hajra Malik, Samira Lakhani, Adeeb Kanji, Khairunnissa Hooda

Journal of Asian Midwives (JAM)

Introduction: Early childhood development (ECD) is a critical period that lays the foundation for a child's future growth and overall well-being. Healthcare settings play a significant role in shaping these developmental outcomes. However, there is limited research evaluating healthcare professionals' knowledge, attitude, and practices on ECD in Pakistan. This study aims to assess the awareness, attitudes, and practices of healthcare providers working in secondary hospitals regarding ECD.
Methods: A sequential explanatory mixed-methods approach was used. The study initially recruited healthcare workers, including physicians, nurses, trainees, and midwives from two secondary care hospitals. Participants completed the Caregiver Knowledge of Child Development …

Development And Validation Of Risk Assessment Tools For Hypertensive Disorder In Pregnancy, Vanitha K, Hepsibah Sharmil, Vijayalakshmi Kandasamy

Journal of Asian Midwives (JAM)

Aims and Background: Hypertensive disorders in pregnancy (HDP) have significant impact on both mothers and newborns leading to complications such as Eclampsia, Preterm delivery, Renal and cardiac problems, Intra Uterine Growth Retardation (IUGR) and Intra Uterine Fetal Death (IUFD). Early screening of hypertensive disorders in pregnancy is essential in the prevention and management of these complications. This research study aims to develop and validate a risk assessment tool for hypertensive disorders in pregnancy.
Materials and methods: A mixed-method research was carried out from December 2023 to December 2024 consisting of two steps. Step one involved the development of …

The Guardian The Month Of July 2025, Wright State Student Body

The Guardian Student Newspaper

News articles from The Guardian for the Month of July 2025. The Guardian is the official student-run newspaper for Wright State University. It has been published regularly since March of 1965.

Nsu Library Link - Summer 2025 - Volume 2.1, Nova Southeastern University

NSU Florida Link Newsletter

No abstract provided.

Implementing A Screening Tool To Increase Palliative Care Referrals For Patients With Metastatic Cancer, Rebecca N. Hegwood

Doctor of Nursing Practice Projects

Background: Palliative care (PC), when prescribed early for patients with metastatic cancer, has proven beneficial to the oncology patient and family by improving quality of life, decreasing stressors, and preventing premature discontinuation of therapy.

Purpose: This Doctor of Nursing quality improvement project aimed to determine if implementing a screening tool for patients newly diagnosed with metastatic cancer would increase PC referrals.

Project Design: The Five Item Palliative Care Screening Tool evaluated patients with a new metastatic cancer diagnosis. Secondary data was used to initiate a PC referral if the patient scored a five or greater on the screening tool. Project …

Customizing Ai Strategies Across Multiple Generations, Matthew Harrer

Theses

This project investigates how artificial intelligence can help brands and marketers connect more effectively with Generation X, Millennials, and Generation Z. The literature review lays the groundwork that focuses on consumer behaviors and the integration of AI into digital marketing practices for each generation. The second part of the project involves a secondary data analysis of 21 recent marketing surveys and reports that explores topics related to trust, personalization, and social media. By integrating the findings into an insightful guidebook, marketers will be able to maximize these insights into clear actionable strategies.

Fostering Resilience Through Near Peer Mentorship In Elementary School, Bway Paw

School of Education and Leadership Student Capstone Projects

Near-peer mentoring involves pairing students with peers who are close in age but slightly more advanced in experience ensures the students' needs are met in ways that feel supportive and accessible. This capstone project explores how peer mentoring fosters social-emotional resilience in elementary students. The project is designed for a ten-week curriculum using the Minnesota SEL standard, which uses CASEL’s five competencies to be integrated into the classroom. Frameworks that carry this project include Bandura's social learning theory and self-efficacy, Vygotsky's Zone of Proximal Development (ZPD), Identity-Based Motivation (IBM), along with Masten’s ordinary magic. Research on resilience highlights that resilience …

Childhood Obesity Body Mass Index And Gut Microbiome: A Cluster Randomized Controlled Pilot Feasibility Study, Marilyn Frenn, Nita Salzman, Vy Lam, Mary Holtz, Andrea Moosreiner, Mauricio Garnier-Villarreal, Maharaj Singh

College of Nursing Faculty Research and Publications

Background:

Prebiotic fiber has been examined as a way to foster gut bacteria less associated with obesity. Tests of prebiotic fiber in reducing obesity have occurred mainly in animals, adults, and Caucasians when the highest obesity rates are in African American and Latinx youth. Response to prebiotic fiber is determined by the pre-existing intestinal microbiota. The type of microbiota varies based on diet and physical activity (PA), so it is important to examine acceptability and response to prebiotic fiber in those most at risk for obesity.

Methods:

This cluster randomized controlled feasibility trial included an online program designed to improve …

Navigating Through Difficult Roads And Terrains: Novice Teachers’ Challenges In Teaching In Remote Mountainous Settings In The Philippines, Albert C. Albina, Sarah Jean A. Salmorin, Dannyla N. Cainos, Rhea Mae C. Montano

The Rural Educator

In rural areas, the adaptation of urban-originating elementary teachers to remote mountainous school locations poses substantial challenges and necessitates innovative strategies. This study primarily explored the lived experiences of newly hired elementary teachers residing in urban areas but assigned to remote mountainous locations, specifically focusing on their adaptation processes, the challenges they encountered, and support mechanisms that influenced their teaching roles. Using a descriptive phenomenological approach and reflexive thematic analysis, this study involved in-depth interviews with nine newly hired urban-originating elementary teachers who were assigned to teach in rural schools in the Municipality of Santa Catalina, Basay, and Bayawan City, …

Distinct Patterns Of Weight Gain, Age, And Subcortical Microstructure In Early Adolescence, Shana Adise, Zhaolong Adrian Li, Jonatan Ottino-González, Filip Morys, Peter A Chiarelli, Tamara Hershey

2020-Current year OA Pubs

IMPORTANCE: Associations between childhood obesity and brain microstructural differences have been observed. It remains unknown whether these associations are driven by sex-specific excessive weight gain. Restriction spectrum imaging characterizes brain tissue microstructural health via water diffusion, where the restricted normalized isotropic (RNI) compartment assesses neuronal and glial cellularity, which may reflect neuroinflammation, synaptic pruning, or both.

OBJECTIVE: To identify associations among RNI scaling factor values, normal neurodevelopment, and weight gain during early adolescence.

DESIGN, SETTING, AND PARTICIPANTS: This cohort study used data from the Adolescent Brain Cognitive Development (ABCD) Study, a 10-year, ongoing, multisite longitudinal cohort study conducted among youths …

Where Should The Cancer Control Interventions Target: A Geospatial Hotspot Analysis For Major Cancer Mortality 2018 To 2022 In The United States, Chongliang Luo, Saira Khan, Liyan Jin, Aimee S James, Graham A Colditz, Bettina F Drake

2020-Current year OA Pubs

BACKGROUND: Identifying changes in geographic disparities of cancer mortality reveals locations where cancer prevention and control efforts should be focused/targeted. We use recent cancer surveillance data to demonstrate the geographic disparity of major cancer mortality rates in the United States and its shift compared with previous data.

METHODS: This cross-sectional study used the 2018 to 2022 county-level mortality rates of colorectal, lung, breast, and prostate cancers from the Centers for Disease Control mortality data. Counties with suppressed death counts were imputed by spatial regression models. Getis-Ord Gi* statistics were used to evaluate the spatial clustering of county mortality. Identified hotspot …

Cultural Competency Of Teachers And Its Effect On Their Instructional Practices, Martin Sims

Theses and Dissertations

Core content teachers at S Middle School participate in a study that reveals how increased cultural competency levels among 7^th-grade core content teachers positively influences their instructional practices. The increased cultural competency led to a more inclusive and effective learning environment across all core content areas. Throughout the study, teachers reflected on their own cultural identities while also considering the diverse cultural backgrounds of their students in each class period. As a result, teachers gained a deeper understanding of how cultural factors shape students' learning experiences and needs. The participants adjusted their teaching strategies to better connect with …