Digital Commons Network^™

The Law Of The New Musical Author, Eyal Brook

Cardozo Arts & Entertainment Law Journal

The process of musical creation has been transformed materially in the Digital Age due to technological developments, both regarding the technologies for making music and regarding novel stylistic developments. New musical practices, based on novel technology, afford entirely new modes of creative authorship. The effects of such shifts have redefined the nature of music and the role of musicians in fundamental ways. This article opens a new debate regarding the identity ofthe new musical author and the changes to the musical creative process.

As such changes have impacted the musical creative process, there are necessary changes required to adapt the …

Consumer Justice: Do Europeans Know Something We Do Not?, Magdalena Tulibacka

Emory International Law Review

No abstract provided.

Comparative Reasoning In Court Rulings In The Aftermath Of Dieselgate, Maria José Azar-Baud

Emory International Law Review

No abstract provided.

Cathepsin D And Its Relation With Lipid Profile In Coronary Atherosclerosis Patients, Israa Saad Salim, Walaa Ismael Jassim, Ahmed Saadi Hassan

Al-Esraa University College Journal for Medical Sciences

Background: Coronary atherosclerosis is a long lasting and continuously evolving disease with multiple clinical manifestations ranging from asymptomatic to stable angina, acute coronary syndrome (ACS), heart failure (HF) and sudden cardiac death (SCD). The onset and advancement of coronary atherosclerosis are influenced by both genetic and environmental factors. Objectives: The study aimed to find out if cathepsin D a good indicator to diagnose atherosclerosis and cardiovascular diseases and its relation with lipid profile. Materials and Methods: The study conducted with the participation of 150 subjects (100 patients with coronary atherosclerosis and 50 healthy control). Age for all subject was in …

Beginnings: Nsw Teachers' Views On The Early Stages Of Implementing A New National Curriculum, Julie-Anne Seach

Theses

This PhD study researched NSW teachers’ conceptions of curriculum change after the introduction of a new Australian national curriculum. One key rationale for the development of a national curriculum in Australia was to raise the standard of education by providing excellent curriculum to students in all Australian states and territories. However, educational standards improve through a combination of many factors, including quality teaching.

A curriculum’s success is dependent on the teachers who implement it. While the curriculum itself garnered considerable attention, how classroom teachers responded to it was likely to be a contributing factor to its overall success. Yet, there …

Educators’ Perspectives On University Technology Transfer Processes In The Philippines: A Case Study, Leni Garcia, Kenbert Alan Ting, Mark Van Hoorebeek

Asia-Pacific Intellectual Property Management and Innovation Book Series

As universities extend the scope of their tasks as educational institutions to include technology transfer and commercialization of their faculty’s and students’ research outputs, it becomes necessary to investigate internal systems that facilitate such processes. Existing literature on technology transfer in the Philippines is mostly focused on the transfer of a specific technology, industry–academe research and development (R&D) collaboration, the experience in a specific industry, or the experience in public Philippine higher education institutions (HEIs). The perspectives of educators and researchers who are the recipients of technology transfer services within Philippine HEIs have, so far, not yet been investigated. This …

Perceptions Of Young Members Of The Aeta Community About Their Intellectual Property Rights For Their Traditional Knowledge Systems: Uniquely Magbukun, Juan Kristopier D. Angeles, Xyra M. Angeles

Asia-Pacific Intellectual Property Management and Innovation Book Series

Traditional knowledge systems are innovative and practically address the needs of Indigenous peoples. In the past decades, efforts from various stakeholders have been made to acknowledge Indigenous peoples in policy debates on intellectual property (IP) dialogues. Sharing of ideas and community experiences was practiced among indigenous communities, such as the Aeta community of the Magbukun tribe in Bataan. The said Aeta community has long opened its door to researchers and nonlocals. However, due to the educational assimilation among the young participants, they formed this call for mimicry and recognition of their tradition that made them believe that both public and …

A Star Fell On Florida And The Magic Circle, Stetson Kennedy

The Marjorie Kinnan Rawlings Journal of Florida Literature

No abstract provided.

Temporary Protection For Ukrainians In The European Union: Why Now And When Again, Maryellen Fullerton

Faculty Scholarship

No abstract provided.

Racing And Erasing Parental Rights, Cynthia Godsoe

Faculty Scholarship

No abstract provided.

Kinship Care And Adoption Myopia, Cynthia Godsoe

Faculty Scholarship

No abstract provided.

Carfilzomib-Loaded Ternary Polypeptide Nanoparticles Stabilized By Polycationic Complexation, Preye Mike Agbana, Ji Eun Park, Piotr G. Rychahou, Kyung-Bo Kim, Younsoo Bae

Markey Cancer Center Faculty Publications

Carfilzomib (CFZ) is a second-generation proteasome inhibitor showing great efficacy in multiple myeloma treatment, yet its clinical applications for other diseases such as solid cancers are limited due to low aqueous solubility and poor biostability. Ternary polypeptide nanoparticles (tPNPs) are drug carriers that we previ- ously reported to overcome these pharmaceutical limitations by entrapping CFZ in the core of the nanopar- ticles and protecting the drugs from degradation in biological media. However, preclinical studies revealed that tPNPs would require further improvement in particle stability to suppress initial burst drug release and thus achieve prolonged inhibition of proteasome activity with CFZ …

A Community-Engaged, Mixed-Methods Approach To Prioritizing Needs In A Statewide Assessment Of Community Cancer Needs, Jessica R. Thompson, Todd Burus, Caree R. Mcafee, Christine Stroebel, Madeline Brown, Keeghan Francis, Melinda Rogers, Jennifer Redmond Knight, Elaine Russell, Connie L. Sorrell, Elizabeth A. Westbrook, Pamela C. Hull

Markey Cancer Center Faculty Publications

Introduction Kentucky has the highest all-site cancer incidence and death rate in the US. In 2021, the University of Kentucky Markey Cancer Center convened a steering committee to conduct a statewide community cancer needs assessment (CNA). The goal of the final CNA phase was to gather community input on prioritizing Kentucky’s cancer-related needs and ways to address them. Methods In 2021, we recruited 162 people to participate in online concept mapping, a participatory mixed method, to explore connections and identify priority areas. Fifty-one community members and 111 organizational partners participated in survey-based activities to prioritize 80 items representing key CNA …

Impact Of Age >70 Years On Oncological Outcomes In Patients With Non-Muscle-Invasive Bladder Cancer Treated With Bacillus Calmette-Guérin., Roberto Contieri, Valentina Grajales, Wei Shen Tan, Alberto Martini, Akshay Sood, Patrick J. Hensley, Kelly Bree, Niyati Lobo, Graciela M. Nogueras-Gonzalez, Charles C. Guo, Neema Navai, Colin P. Dinney, Ashish M. Kamat

Markey Cancer Center Faculty Publications

OBJECTIVE: To evaluate the impact of age on oncological outcomes in a large contemporary cohort of patients with non-muscle-invasive bladder cancer (NMIBC) treated with adequate Bacillus Calmette-Guérin (BCG).

PATIENTS AND METHODS: We performed an Institutional Review Board-approved retrospective study analysing patients with NMIBC treated with adequate BCG at our institution from 2000 to 2020. Adequate BCG was defined as per United States Food and Drug Administration (FDA) guidelines as being receipt of at least five of six induction BCG instillations with a minimum of two additional doses (of planned maintenance or of re-induction) of BCG instillations within a span of …

Retinoic Acid-Mediated Inhibition Of Mouse Coronavirus Replication Is Dependent On Irf3 And Camkk, Justin H. Franco, Ryan A. Harris, William G. Ryan, Roger Travis Taylor, Robert E. Mccullumsmith, Saurabh Chattopadhyay, Zhixing K. Pan

Markey Cancer Center Faculty Publications

The ongoing COVID-19 pandemic has revealed the shortfalls in our understanding of how to treat coronavirus infections. With almost 7 million case fatalities of COVID-19 globally, the catalog of FDA-approved antiviral therapeutics is limited compared to other medications, such as antibiotics. All-trans retinoic acid (RA), or activated vitamin A, has been studied as a potential therapeutic against coronavirus infection because of its antiviral properties. Due to its impact on different signaling pathways, RA’s mechanism of action during coronavirus infection has not been thoroughly described. To determine RA’s mechanism of action, we examined its effect against a mouse coronavirus, mouse hepatitis …

Sedimentation Of Large, Soluble Proteins Up To 140 Kda For 1h-Detected Mas Nmr And 13c Dnp Nmr – Practical Aspects, Dallas Bell, Florian Lindemann, Lisa Gerland, Hanna Aucharova, Alexander Klein, Daniel Friedrich, Matthias Hiller, Kristof Grohe, Tobias Meier, Barth Van Rossum, Anne Diehl, Jon Hughes, Leonard J. Mueller, Rasmus Linser, Anne-Frances Miller, Hartmut Oschkinat

Markey Cancer Center Faculty Publications

Solution NMR is typically applied to biological systems with molecular weights < 40 kDa whereas magic-angle-spinning (MAS) solid-state NMR traditionally targets very large, oligomeric proteins and complexes exceeding 500 kDa in mass, including fibrils and crystalline protein preparations. Here, we propose that the gap between these size regimes can be filled by the approach presented that enables investigation of large, soluble and fully protonated proteins in the range of 40–140 kDa. As a key step, ultracentrifugation produces a highly concentrated, gel-like state, resembling a dense phase in spontaneous liquid-liquid phase separation (LLPS). By means of three examples, a Sulfolobus acidocaldarius bifurcat- ing electron transfer flavoprotein (SaETF), tryptophan synthases from Salmonella typhimurium (StTS) and their dimeric β-subunits from Pyrococcus furiosus (PfTrpB), we show that such samples yield well-resolved proton-detected 2D and 3D NMR spectra at 100 kHz MAS without heterogeneous broadening, similar to diluted liquids. Herein, we provide practical guidance on centrifugation conditions and tools, sample behavior, and line widths expected. We demonstrate that the observed chemical shifts correspond to those obtained from μM/low mM solutions or crystalline samples, indicating structural integrity. Nitrogen line widths as low as 20–30 Hz are observed. The presented approach is advantageous for proteins or nucleic acids that cannot be deuterated due to the expression system used, or where relevant protons cannot be re-incorporated after expression in deuterated medium, and it circumvents crystallization. Importantly, it allows the use of low-glycerol buffers in dynamic nuclear polarization (DNP) NMR of proteins as demonstrated with the cyanobacterial phytochrome Cph1.

Interactions Between Multiple Stressors, Nanomaterials And A Pathogen, In Caenorhabditis Elegans, Jarad Cochran

Theses and Dissertations--Plant and Soil Sciences

Metal and metal oxide nanoparticles (NP), which have received interest for use in agriculture, show in vitro and in vivo toxicity at relatively low concentrations. Silver nanoparticles (Ag NP) and zinc oxide nanoparticles (ZnO NP) cause adverse effects in model soil organisms under environmentally relevant conditions. In most toxicity assessments of nanomaterials, model organisms are exposed to a single stressor. Though single stressor experiments are essential to understanding the fate and effects of released NP, in nature, organisms are affected by multiple stressors, including pathogens, which might exacerbate or mitigate negative effects of NP exposure. There is limited research on …

The Case For Waivable Employee Rights: A Contrarian View, William Corbett

Journal Articles

No abstract provided.

The Once And Future Clean Air Act: Impacts Of The Inflation Reduction Act On Epa's Regulatory Authority, Nicholas Bryner

Journal Articles

The Clean Air Act is one of Congress's greatest success stories. The major piece of legislation, passed in the context of environmental and public health crises, has driven technological change through regulation that has dramatically improved air quality even in a prolonged period of economic growth. In the context of climate change, however, despite many efforts since the 1990s, the Clean Air Act has not proven to be a successful legislative tool. Instead, the Act has faced complex obstacles in the statutory language and a trend in Supreme Court jurisprudence-leading up to and including the June 2022 decision in West …

Judicial Fidelity, Caprice L. Roberts

Journal Articles

Judicial critics abound. Some say the rule of law is dead across all three branches of government. Four are dead if you count the media as the fourth estate. All are in trouble, even if one approves of each branch’s headlines, but none of them are dead. Not yet.

Pundits and scholars see the latest term of the Supreme Court as clear evidence of partisan politics and unbridled power. They decry an upheaval of laws and norms demonstrating the dire situation across the federal judiciary. Democracy is not dead even when the Court issues opinions that overturn precedent, upends longstanding …

Local Government Regulation Of Ccs, Keith B. Hall

Journal Articles

Carbon capture and storage is being used in an increasing number of locations in the United States as a tool to address climate change, and many more projects are in the planning stages. Although government, industry, and some prominent environmental organizations support the use of CCS, some environmental organizations and many citizens who live in the vicinity of proposed CCS projects oppose CCS. This has prompted several local governments to enact ordinances that attempt to prohibit or regulate CCS. These ordinances take many forms-moratoria, zoning restrictions and setbacks, effective bans, outright bans, construction and operational restrictions, and various other types …

Taxonomic Revision Of The Soil Genus Trichocoleus (Trichocoleusaceae, Cyanobacteria), Including Four New Species From White Sands National Park, New Mexico, Amanda Szinte

Masters Theses

Cyanobacteria have never received molecular characterization in the gypsum soils at White Sands National Park. These gypsiferous soils support distinctive plant communities and considerable microbial taxonomic diversity in their biological soil crusts. Employing a polyphasic approach characterizing both morphology and sequencing of the 16S rRNA gene and associated 16S-23S ITS region, six strains of Trichocoleus isolated from White Sands biocrusts were fully characterized. Phylogenetic analyses including other as-yet-unnamed Trichocoleus strain sequences and the three previously described species, T. desertorum, T. caatingensis, and T. badius, led to a revision of the genus and identification of 17 unnamed species-level groups within Trichocoleus. …

Systems Check: A Qualitative Case Study Of Educators And Parent-Educators Supporting Adolescent Readers From An Ecological Systems Perspective, Kristi Nicole Grooms

Theses and Dissertations

In spite of decades of research and an abundance of well-intentioned intervention efforts, supporting adolescent readers, particularly at the middle level, remains a significant area of concern for educators in the United States. The struggles are present for educators working to help underperforming readers reach grade-level and keep advanced readers motivated and engaged. At home, parents and guardians experience similar challenges. Data on adolescent comprehension performance continues to be frustrating in terms of producing consistent positive results. This qualitative action research study investigated the ongoing challenge of supporting adolescent readers, specifically within the context of 7th grade, through a systems …

Young Children's 21st Century Mathematical Skills And The Role Of The Early Childhood Environment In Developing These Skills, Mistelle Moore

Theses

This research examined the preparation of young children in an Early Years school environment in the development of 21st Century mathematical skills including critical thinking, problem-solving, innovation, collaboration, creativity, and communication. The research used a field-based case study using qualitative data collection methods, and the data were reviewed using thematic analysis. The research explores the pedagogical strategies employed by an Early Years teacher and the interplay of various stakeholders in nurturing 21st Century mathematics competencies among young learners. Key findings of the research indicated that there were eight elements that Early Years teachers should apply in their mathematics lessons as …

Influences Of Professors' Personality Traits, Teaching Styles, And Generational Affiliation On Technology Acceptance: A Mixed-Methods Exploration Of Blended Learning Readiness, Joey K. Freeman

Education Dissertations

The abrupt transition to emergency remote teaching during the COVID-19 pandemic offered minimal time to prepare, resulting in faculty reliance on prior pedagogical practices in the shift to an online instructional environment. Although the pandemic altered the learning environment in the short-term, it also offered a glimpse of how higher education institutions (HEIs) could transform their learning environments in the long-term. Though a body of literature exists on factors that influence technology acceptance, a limited number of studies have explored personality traits, teaching styles, and generational affiliation. An adapted Technology Acceptance Model considered these variables as antecedents to perceptions, attitudes, …

School Librarians’ Self-Efficacy As Educational Technology Coaches, Becky P. Johnson

Education Dissertations

Although school librarians adapt and continue to thrive through radical changes, one in five school librarian positions are cut due to a loss of funding. One way school librarians can promote their knowledge in digital and information literacy and their skills as education leaders is to serve as educational technology (EdTech) coaches in their school community. With the influx of EdTech in schools, districts are shifting budgets and quickly adding technology-focused jobs, which leaves other positions at risk for job loss. This exploratory mixed-methods study examined the self-efficacy of school librarians to serve as EdTech coaches through the lens of …

Biomechanical Outcomes Of Distinct Tka Surgical Alignments And Implant Designs, Alexis Kathleen Nelson-Tranum

Theses and Dissertations (ETD)

Introduction. Total knee arthroplasty (TKA) has advanced over the past two decades from traditional post-operative neutral alignment methods with an overall goal of implant longevity to ones that are more personalized to better replicate individual native knee kinematics. Personalizing TKA knee kinematics to better replicate a patient’s native knee kinematics has evolved in response to a reported 20% dissatisfaction by patients with their TKA. These personalization advancements include innovations in surgical alignment techniques include the kinematic alignment (KA) and joint line obliquity (JLO) restoration, in contrast to the mechanical alignment (MA) technique that places everyone into the same mold. Additionally, …

Multi-Physics Modeling Of Immersion Cooled Electric Power Apparatuses, Reza Ilka

Theses and Dissertations--Electrical and Computer Engineering

Electric power conversion apparatuses such as electromagnetic transformers and power electronic converters play a backbone role in the global power and energy industries, such as power transmission and distribution, electrified transportation vehicle systems, industry automation, and the like. To investigate the performance (efficiency, reliability, etc.) of such critical power conversion apparatuses, high-fidelity multi-physics modeling becomes critical which involves dedicated coupling among multiple physical domains, including electrical, magnetic, thermal, mechanical, and material engineering. Nevertheless, the majority of the existing models for these power conversion apparatuses focus only on one or two physical domains, and the modeling fidelity needs to be further …

Inclusive Publishing Strategies For Journal Staff And Prospective Authors In The Digital Humanities, Rachel Schrauben Yeates

Master's Projects

In this project, I will share the inclusive strategies and solutions to common pitfalls I observed in my exploratory review of a selection of DH online journals and share Inclusivity Guides tailored to journal staff and prospective authors to perform a quick audit of journal site design and content. I paid special attention to the information available to researchers considering submitting their work for publication. Which journals leave a good impression and provide potential authors with enough information to confidently submit their work? How can prospective authors assess a journal’s commitment to furthering and practicing inclusivity in their field, and …

Prepared Foods Photos V. Chicken Joes, Southern District Of New York

Historical and Topical Legal Documents

No abstract provided.