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Protocol For A Pilot Clinical Trial Of The Senolytic Drug Combination Dasatinib Plus Quercetin To Mitigate Age-Related Health And Cognitive Decline In Mental Disorders [Version 2; Peer Review: 1 Approved, 2 Approved With Reservations], Abigail Schweiger, Breno Diniz, Ginger Nicol, Julie Schweiger, Andes E Dasklakis-Perez, Eric J Lenze Jan 2024

Protocol For A Pilot Clinical Trial Of The Senolytic Drug Combination Dasatinib Plus Quercetin To Mitigate Age-Related Health And Cognitive Decline In Mental Disorders [Version 2; Peer Review: 1 Approved, 2 Approved With Reservations], Abigail Schweiger, Breno Diniz, Ginger Nicol, Julie Schweiger, Andes E Dasklakis-Perez, Eric J Lenze

2020-Current year OA Pubs

BACKGROUND: Major depressive disorder (MDD) and schizophrenia are linked to accelerated aging leading to reduced lifespan, health span and cognitive decline. Cellular senescence, in which cells lose proliferative capacity and develop a senescence-associated secretory phenotype (SASP), plays a role in this process. Emerging research suggests that the senolytic regimen of dasatinib+quercetin (D+Q) reduces senescent cells, potentially mitigating age-related health and cognitive decline. This pilot study aims to assess the feasibility and safety of D+Q in older adults with schizophrenia, schizoaffective disorder, and treatment-resistant depression (TRD).

METHODS: This single-center study will recruit 30 participants total aged 50 years or older with …


What Mediation Romantics Can Learn From The Model T (Or Maybe The Chevrolet Trax), Nancy A. Welsh Jan 2024

What Mediation Romantics Can Learn From The Model T (Or Maybe The Chevrolet Trax), Nancy A. Welsh

Faculty Scholarship

When mediation was reintroduced to the U.S. in the 1970s, it was infused with a democracy-and-self-determination-enhancing, social justice ethos. As the process has been very successfully institutionalized, however, these ambitions have been scaled backalthough, at least arguably, certain "mediative elements" have actually been adopted (or coopted) by other procedural innovations. Perhaps it is time for those of us frustrated with the evolution of mediation to reconcile ourselves to the reality and value of a "basic" model of mediation designed for the sole purpose of getting parties from dispute to settlement-in much the same way that the basic model of a …


Making The Most Of Sushi In Alma: Tips For Smooth Maintenance And Reporting, Marie Day, Laura Beane Jan 2024

Making The Most Of Sushi In Alma: Tips For Smooth Maintenance And Reporting, Marie Day, Laura Beane

Faculty Articles

SUSHI is a widely used protocol in academic libraries. This article discusses maintaining SUSHI vendor accounts in Alma, troubleshooting irregularities, and finding technical support. This article also includes sample analyses for the ACRL survey 60B Digital/Electronic Circulation or Usage and 63 E-serials Usage using COUNTER 5 reports.


Discovery: The Student Journal Of Dale Bumpers College Of Agricultural, Food And Life Sciences - Volume 25 2024, Several Authors Jan 2024

Discovery: The Student Journal Of Dale Bumpers College Of Agricultural, Food And Life Sciences - Volume 25 2024, Several Authors

Discovery, The Student Journal of Dale Bumpers College of Agricultural, Food and Life Sciences

No abstract provided.


Evaluating Efficiency And Accuracy Of Three Texture Analysis Methods For Blackberry Fruit, Rhys M. Brock, Carmen Johns, Katelyn Lust-Moore, Margaret Worthington Jan 2024

Evaluating Efficiency And Accuracy Of Three Texture Analysis Methods For Blackberry Fruit, Rhys M. Brock, Carmen Johns, Katelyn Lust-Moore, Margaret Worthington

Discovery, The Student Journal of Dale Bumpers College of Agricultural, Food and Life Sciences

A major objective of the University of Arkansas System Division of Agriculture (UADA) Fruit Breeding program is to improve the texture of blackberry (Rubus subgenus Rubus Watson). Blackberry varieties with improved fruit firmness transport and store well and may maintain superior quality under challenging postharvest conditions than softer varieties. Increased firmness may also make cultivars less susceptible to red drupelet reversion (RDR), a postharvest disorder of blackberries in which fully black drupelets revert to red after harvest. This research project aims to assess the efficiency and accuracy of three methods applied in evaluating blackberry firmness. The study compares instrumental analysis …


Thematic Mapping Of Apidae Holdings Within The University Of Arkansas Arthropod Museum, Baylie L. Day, Ashley P.G. Dowling, Austin Jones Jan 2024

Thematic Mapping Of Apidae Holdings Within The University Of Arkansas Arthropod Museum, Baylie L. Day, Ashley P.G. Dowling, Austin Jones

Discovery, The Student Journal of Dale Bumpers College of Agricultural, Food and Life Sciences

Museum biological collections store species data that can be utilized in research on biodiversity, environmental change, invasive species, public health, and disease. The University of Arkansas Arthropod Museum, which began in 1905, houses over 750,000 specimens and has not yet been digitized. Making data publicly accessible via the internet makes the data available to the entire scientific community. The goal of this project was to create a digital resource to allow greater access to the University of Arkansas Arthropod Museum holdings. To do so, data from Bombus (bumble bee) and Xylocopa (carpenter bee) specimens were entered into a database in …


Fast Fashion, Luxury Fashion, And Their Sustainability Efforts, Danielle L. Illum, Lance Cheramie Jan 2024

Fast Fashion, Luxury Fashion, And Their Sustainability Efforts, Danielle L. Illum, Lance Cheramie

Discovery, The Student Journal of Dale Bumpers College of Agricultural, Food and Life Sciences

The apparel industry can be divided into two categories: fast fashion and luxury fashion. It’s no secret that the apparel industry has a negative impact on our world in terms of sustainability, greenwashing, pollution, and human rights issues. Although the entire apparel industry plays a role in this, fast fashion seems to be at the forefront of these issues. It is necessary to understand the growth and consumer obsession with fast fashion to grasp its negative impact. In the same way, understanding the importance of luxury fashion to the consumer along with the strides being made by luxury fashion companies …


“There’S A Lifestyle, An Appreciation, A Beauty”: An Interpretative Phenomenological Analysis Of Masters Rowers, Jason Rich, Pamela Beach, Heidi K. Byrne Jan 2024

“There’S A Lifestyle, An Appreciation, A Beauty”: An Interpretative Phenomenological Analysis Of Masters Rowers, Jason Rich, Pamela Beach, Heidi K. Byrne

Articles

Masters rowing has seen a measurable increase in participation, with masters rowers engaged in the sport for competition, health, and recreation reasons. Unlike other masters sports, masters rowing has a unique high level of synchronous, cooperative, and interdependent elements. To better understand the benefits and challenges of participation in competitive masters rowing, the purpose of this study was to explore the lived experiences of competitive masters rowers. Twelve competitive masters rowers were recruited and interviewed. Utilizing an interpretative phenomenological analysis approach to guide data collection, analysis, and interpretation, the analysis revealed four major themes: navigating community relationships, finding a reason …


Not Just Bony Fish: All Nonmammalian And Nonavian Animals Are Neglected In Both Welfare And General Research, Jennifer A. Mather Ph.D. Jan 2024

Not Just Bony Fish: All Nonmammalian And Nonavian Animals Are Neglected In Both Welfare And General Research, Jennifer A. Mather Ph.D.

Animal Sentience

The lack of research on fish welfare highlighted by Oldfield & Bonano (2024) is only part of a more general problem: a relative neglect of animals other than mammals and birds. The causes are our lack of knowledge, our negative view of what we consider to be “lower” animals and our underestimation of their intelligence and sensitivity. Our estimation will increase as our knowledge increases. As a broader view spreads to the public through the media, it should gradually increase the demand to expand both research and welfare, especially beyond mammals and birds.


Editorial Note: Designing Microlearning For How People Learn, Joseph Rene Corbeil, Maria Elena Corbeil Jan 2024

Editorial Note: Designing Microlearning For How People Learn, Joseph Rene Corbeil, Maria Elena Corbeil

Teaching and Learning Faculty Publications

Although the term microlearning has been around since 2005 (Hug, 2005), it has regained popularity in recent years due to the increasing mobility and competing priorities of adult learners. Today’s learners seek smaller, focused lessons that deal with a single topic and can be consumed quickly. Yet, there are still many questions surrounding what microlearning entails, how it should be designed, who it is intended for, and how the learning in microlearning can be assessed. This special issue aims to explore the design, development, implementation, and assessment of microlearning, with an emphasis on designing microlearning experiences with today’s learners in …


Gender Difference On Internal Equity: Evidence From The Hospitality Industry In Ghana, Patricia Peprah Jan 2024

Gender Difference On Internal Equity: Evidence From The Hospitality Industry In Ghana, Patricia Peprah

Faculty Publications

It is a hypothetical position that employees in the hospitality industry in Ghana experience salary disparities based on the gender of the employee. Pay disparities exist because of unconscious biases in areas such as hiring, promotions, performance reviews, and salary decisions. In ensuring equal pay for equal work to fulfill the International Labor Organization (ILO) convention, this study investigated the internal equity pay of the employees in Ghana's hospitality industry based on equal work. This quantitative association study adopted a self-constructed research instrument to measure internal equity pay and randomly selected 350 respondents in the hospitality industry in Ghana to …


A Systematic Review Of Adolescent Girls’ Perception Of Body Image And Self-Esteem Through Participatory Digital Storytelling Groups, Alecia R. Jones Jan 2024

A Systematic Review Of Adolescent Girls’ Perception Of Body Image And Self-Esteem Through Participatory Digital Storytelling Groups, Alecia R. Jones

Theses and Dissertations

Adolescent girls face increased pressure to conform to societal standards. As social beings, adolescent girls gravitate to social media as an outlet for peer interaction, community, and validation. Research has found that at the critical age of adolescence, 12-18, girls experience appearance comparison on social media, which can lead to internalizing unrealistic beauty standards and negative self-appraisal. Digital storytelling emerges as a source of encouragement, providing a platform for empowerment, self-expression, community engagement, and a safe space for adolescent girls to share their body image and self-esteem experiences. This Systematic Review sought to synthesize findings of qualitative and mixed-methods studies …


Perceptions Of Classroom Technology Use Among Adult English Learners, Mandy Chien Jan 2024

Perceptions Of Classroom Technology Use Among Adult English Learners, Mandy Chien

Theses and Dissertations

The purpose of this study was to assess adult English Learners’ perceptions of using Microsoft Teams in classes. Specifically, the study aims to explore the strength and direction of the correlation between the elements of the technology acceptance model (TAM) and using Microsoft Teams in English language courses. This study addressed the following research question: What are the strengths and directions of the correlations between the elements of the technology acceptance model and the use of Microsoft Teams among adult ELs?

The researcher utilized a quantitative methods approach to investigate the relationship between TAM variables and the use of Microsoft …


Psychosocial Factors Impacting Identity Development In Biracial-Biethnic Youth: A Socioecological Analysis, Melanie S. David Jan 2024

Psychosocial Factors Impacting Identity Development In Biracial-Biethnic Youth: A Socioecological Analysis, Melanie S. David

Theses and Dissertations

A mixed methods systematic review with socioecological analysis was conducted to identify specific psychosocial factors impacting identity development and well-being and biracial-biethnic youth. Findings from this review aimed to summarize and synthesize the most recent research literature on biracial-biethnic youth, with particular attention to factors contributing to negative identity development, psychosocial stressors (e.g., substance use) that impact both identity and well-being, and protective factors that promote well-being. This systematic review also aimed to utilize a socioecological framework to better understand on what level these psychosocial factors occur and the interaction between the individual and the larger environment. Methods. Data was …


Exploring The Perceived Effects Of Online And Hybrid Learning On The Experiences Of Students In Nigerian Universities, Amaechi Ugwu Jan 2024

Exploring The Perceived Effects Of Online And Hybrid Learning On The Experiences Of Students In Nigerian Universities, Amaechi Ugwu

Theses and Dissertations

Recent years have seen an apparent increase in the popularity and acceptance of online and hybrid learning as alternative models of learning at universities and other institutions of higher education in Nigeria. However, there is doubt whether the increase in popularity and acceptance of online and hybrid learning has translated to better learning conditions or satisfaction for students and graduates of higher education. These issues among others have made online and hybrid learning models to represent an area of growing academic interest by scholars. The main purpose of this study was to explore the perceived effects of online and hybrid …


Utilizing Social Media As An Assistive Technology Tool For Children With Autism Spectrum Disorder, Meaghan Donahue Jan 2024

Utilizing Social Media As An Assistive Technology Tool For Children With Autism Spectrum Disorder, Meaghan Donahue

Theses and Dissertations

The number of children diagnosed with autism has continued to rise since 2000 at startling rates, leading to an increased need for schools to discover innovative ways to meet the unique learning needs of these students. Technology has proven to be adaptable and successful in teaching social skills to children with autism. Assistive technology and the continuing development of online platforms offer unique opportunities for children with special needs to access the general education curriculum. This combined with the increased usage of social media among school-aged children, make it a potential tool for learning. Understanding how social media can be …


The Great Race, Willard Bullock Jan 2024

The Great Race, Willard Bullock

Theses and Dissertations

No abstract provided.


Impact Of Supervisors’ Person-Centered Listening On Sense Of Belonging Among Occupationally Minoritized Healthcare Professionals, Nelu Nedelea Jan 2024

Impact Of Supervisors’ Person-Centered Listening On Sense Of Belonging Among Occupationally Minoritized Healthcare Professionals, Nelu Nedelea

Theses and Dissertations

Significant gender and racial disparities are evident when comparing the composition of the U.S. healthcare workforce to the general U.S. population. Latinx individuals are underrepresented across all professions, while non-White individuals and women are occupational minorities in executive roles and in physician, surgeon, and advanced practitioner roles. Lack of diversity poses problems for underrepresented healthcare professionals, their organizations, and their patients. While diverse professionals experience various forms of microaggression, discrimination, prejudice, and diminished sense of belonging in their fields, these conditions can compromise communication among the various healthcare professionals involved with a patient, in turn, potentially threatening patient safety and …


Mandated Sexual Violence Prevention In Higher Education: A Quantitative Analysis Of Student Response To Sexual Harassment And Violence Through A Framework Of Organizational Culture, Andrew L. Jones Jan 2024

Mandated Sexual Violence Prevention In Higher Education: A Quantitative Analysis Of Student Response To Sexual Harassment And Violence Through A Framework Of Organizational Culture, Andrew L. Jones

Theses and Dissertations

Sexual violence (SV) is a global public health crisis of pandemic proportions. Sexual harassment (SH) and violence are pervasive on college campuses, negatively impacting students, faculty, and staff. To address this, U.S. universities are required by federal law to implement EBP programs to foster awareness, knowledge, attitudes, and skills/behaviors (competencies) to prevent or mitigate sexual misconduct. Improving these competencies can increase students’ capacity to respond to SH and SV they experience or witness positively impacting retention, health, wellness, and graduation outcomes. Additionally, recent empirical evidence has linked organizational culture (i.e., values, shared beliefs, and artifacts) and competencies to effectively responding …


On Writing For Screen And Television, David L. Espey Jan 2024

On Writing For Screen And Television, David L. Espey

Theses and Dissertations

No abstract provided.


Leadership Best Practices In Fostering Collaboration For Transformative Change In International Nongovernmental Organizations: A Phenomenological Study, Colton Manley Jan 2024

Leadership Best Practices In Fostering Collaboration For Transformative Change In International Nongovernmental Organizations: A Phenomenological Study, Colton Manley

Theses and Dissertations

For nearly a century, International Non-Governmental Organizations (INGOs) have spearheaded humanitarian relief and development efforts worldwide. However, the increasing complexity and interconnectivity of global challenges demand a fundamental shift in the operations of INGOs. Collaboration has emerged a key strategy in driving systemic change and addressing the root causes of complex issues. Leaders play a pivotal role in fostering these essential relationships and cultivating a collaborative ecosystem. While leadership remains paramount, there is a critical need to understand how INGO leaders can cultivate transformative collaboration, a collaborative approach aimed at addressing the root causes of complex issues and driving systemic …


Not At The Expense Of Me: Best Practices For Black Women Diversity, Equity, Inclusion, And Social Justice Practitioners In Higher Education, Brittney Michelle Elese Fink Jan 2024

Not At The Expense Of Me: Best Practices For Black Women Diversity, Equity, Inclusion, And Social Justice Practitioners In Higher Education, Brittney Michelle Elese Fink

Theses and Dissertations

This qualitative research paper investigated the intersection of the COVID-19 pandemic and the year 2020 in sparking a phenomenon of hiring chief diversity officers (CDOs) in higher education. By exploring the interplay between the pandemic, racial justice movements, evolving higher education landscape, and institutional accountability, this study aimed to understand the motivations behind the increased hiring of CDOs during this transformative period. Additionally, this research examined the specific effects of this phenomenon on Black women diversity, equity, inclusion and social justice (DEI&J) professionals in higher education. The findings contribute to a deeper understanding of the opportunities and challenges faced by …


The Success Strategies Of The Iranian-American Women Who Initially Received Their Primary And/Or Secondary Education In The Post-Revolution Iranian Education System In Attaining Higher Education Degrees In The United States, Niloufar Mirhashemi Jan 2024

The Success Strategies Of The Iranian-American Women Who Initially Received Their Primary And/Or Secondary Education In The Post-Revolution Iranian Education System In Attaining Higher Education Degrees In The United States, Niloufar Mirhashemi

Theses and Dissertations

The driving theme for this research was cultural discontinuity as experienced in the American academic institutions. Cultural discontinuity is understood as a way in which the cultural practices and values of students’ home culture affect the academic achievements of the students usually, resulting in low academic accomplishments. This phenomenon can be triggered by the existing disparities and gaps in the educational and cultural structures of a society. This research investigated the encounters, challenges, and perspectives of women born in Iran who initially received their primary and/or secondary education in the post-revolution Iranian education system and later obtained college degrees in …


Beyond The Classroom: Unraveling The Impact Of Student Engagement On Graduation Rates In New York City, Kimberly Mccall Jan 2024

Beyond The Classroom: Unraveling The Impact Of Student Engagement On Graduation Rates In New York City, Kimberly Mccall

Theses and Dissertations

This study critically examined the impact of student engagement on high school graduation rates amidst the educational disruptions ushered in by the COVID-19 pandemic, with a concentrated focus on the United States. It evaluated the essential engagement factors--rigorous instruction, collaborative teaching, supportive environments, and trust--and their role in addressing disparities in graduation outcomes (New York City Panorama, 2022; Wang & Degol, 2014). Anchored in the theoretical frameworks of Bronfenbrenner’s ecological systems theory (Bronfenbrenner, 1979), social-emotional learning theory (Durlak et al., 2011; Williamson et al., 2015), and Vygotsky’s sociocultural theory (Vygotsky, 1987), this research utilized a comprehensive quantitative analysis of data …


Blogging Mastery: Analyzing The Key Strategies Behind Successful Blogs, Michael Llamas Jan 2024

Blogging Mastery: Analyzing The Key Strategies Behind Successful Blogs, Michael Llamas

Theses and Dissertations

Bloggers in the digital landscape have the power to shape consumer behavior and influence their peers. However, successfully running a blog demands time and commitment, similar to operating a small business. Yet, there is scant literature regarding successful practices and strategies that bloggers use to build their blogs and remain successful. This study explores bloggers' most effective methods and strategies to establish themselves in their respective niches. The qualitative research study uses transcendental phenomenology to examine the lived experiences of successful bloggers, aiming to provide insights into their successful strategies, best practices, challenges, and insights for new bloggers. Twelve bloggers …


Strategic Framework For Achieving Successful Sustainable Tourism In Egypt, Maher Abdelwahab Jan 2024

Strategic Framework For Achieving Successful Sustainable Tourism In Egypt, Maher Abdelwahab

Theses and Dissertations

This phenomenological study explored the lived experiences of tourism leaders who operate a tour operator company in Egypt. It sought to examine how the lack of collaborative leadership adversely affects tourism. The study further investigated the challenges the tourism industry faces, and the strategies tour companies’ leaders use to achieve successful sustainable tourism. The study revealed the connection between the challenges, strategies, competitiveness, factors of success, and recommendations to create a strategic framework for successful sustainable tourism. The strategic framework promoted collective tourism leadership and sustainable tourism as significant economic drive in Egypt to reduce poverty, develop society, and bring …


Educators’ Experiences And Perspectives On Teaching Sexuality Education To High School Students In Vietnam, Tram Van Jan 2024

Educators’ Experiences And Perspectives On Teaching Sexuality Education To High School Students In Vietnam, Tram Van

Theses and Dissertations

This qualitative phenomenological study explored experiences of teaching sex education and identified challenges to sexuality education among 10 Vietnamese high school educators. Sexuality education high-school teachers in Vietnam participated in in-depth interviews focused on (a) experiences associated with teaching sex education in Vietnamese high schools and (b) how high school educators’ experiences with professional training related to sex education influenced their teaching practices. This research explored teacher characteristics, curricula, professional development, and environmental factors. Study data were collected via Zoom interviews, enabling the researcher to engage participants in their subjective viewpoints and overcome the hurdles of long-distance travel and health …


The Art Of Online Arbitrage: Essential Practices For Third-Party Sellers, Jesse Llamas Jan 2024

The Art Of Online Arbitrage: Essential Practices For Third-Party Sellers, Jesse Llamas

Theses and Dissertations

The topic of arbitrage is an essential concept in the financial world. It involves taking advantage of price discrepancies for an asset or security across different markets. The emerging third-party retail and online e-commerce arbitrage sellers industry is growing and becoming a popular income source for many individuals. While there is various research on arbitrage and its impact on the economy, there is scant literature on third-party retail e-commerce arbitrage selling. The goal of this research is to build upon existing scholarly work by examining optimal methods, tactics, and obstacles encountered by e-commerce arbitrage sellers who operate through third-party retail …


Quantitative Study On The Efficacy Of Online And Hybrid Learning Formats As Related To The Success Indicators Of Equity, Ali Kowsari Jan 2024

Quantitative Study On The Efficacy Of Online And Hybrid Learning Formats As Related To The Success Indicators Of Equity, Ali Kowsari

Theses and Dissertations

This research involved a quantitative secondary analysis using the Integrated Postsecondary Education Data System (IPEDS) to investigate factors leading to disparities in academic success. Focusing on the role of course modality, the research aimed to address the need to enhance equity in academic achievement, considering age, gender, race, and socioeconomic status. Special attention was given to online and hybrid modalities from 2017 to 2021, encompassing both pre- and post-pandemic data to observe shifts in higher education to more online and hybrid practices. The research was rooted in Astin’s student involvement theory and Rawls’ theory of justice, and it sought to …


My Secret Struggle: Starving, Purging, And Numbing My Emotions. An Autoethnographic Analysis Of My Lifelong Battle With Anxiety, Depression, And Eating Disorders, Hasmek G. Siwajian Jan 2024

My Secret Struggle: Starving, Purging, And Numbing My Emotions. An Autoethnographic Analysis Of My Lifelong Battle With Anxiety, Depression, And Eating Disorders, Hasmek G. Siwajian

Theses and Dissertations

Adolescent females and young adult women between the ages of 12 and 25 are at a higher risk of engaging in self-destructive and life-threatening behaviors linked to anxiety, depression, and eating disorders when they do not have access to suitable treatment options or coping mechanisms (Garcia et al., 2020). This study highlights the heightened vulnerability of adolescent females and young adult women aged 12 to 25 who engage in self-destructive behaviors associated with anxiety, depression, and eating disorders when adequate treatment options or coping mechanisms are lacking. Through an autoethnographic approach, the researcher delves into her daily struggles and breakthroughs …